Pub Date : 2019-05-30DOI: 10.21593/KJHNO/2019.35.1.13
Yong Ju Lee, Y. Koh, S. Yoon, H. Ryu, H. Kim, H. Shin
Background/Objectives: Despite multiple approaches of treatments for salivary duct carcinoma, there has been a need for more successful treatment methods because of its poor prognosis. Treatment options like immunotherapy using new technologies have been attempted. Based on recent study results indicating that targeting programmed death receptors are effective in treating various cancers, this study aimed to identify the frequency of PD-L1 expression and its impact on survival rate in salivary duct carcinoma. Materials & Methods: We studied 33 patients with salivary gland cancer who were available for histologic specimens. We examined the expression of PD-L1 in the tissues and analyzed the association with the survival rate and the association with various clinical parameters. Results: According to this study and review of similar studies, we discovered that the expression of PD-L1 in salivary duct carcinoma was lower than other types of cancers. The impact of PD-L1 on survival rate also showed inconsistency in salivary duct carcinoma. Conclusion: Immunotherapy by PD-1/PD-L1 checkpoint blockade in salivary duct carcinoma needs further evaluation for clinical application.
{"title":"Analysis of PD-L1 expression in salivary duct carcinoma with its efficacy as a tumor marker","authors":"Yong Ju Lee, Y. Koh, S. Yoon, H. Ryu, H. Kim, H. Shin","doi":"10.21593/KJHNO/2019.35.1.13","DOIUrl":"https://doi.org/10.21593/KJHNO/2019.35.1.13","url":null,"abstract":"Background/Objectives: Despite multiple approaches of treatments for salivary duct carcinoma, there has been a need for more successful treatment methods because of its poor prognosis. Treatment options like immunotherapy using new technologies have been attempted. Based on recent study results indicating that targeting programmed death receptors are effective in treating various cancers, this study aimed to identify the frequency of PD-L1 expression and its impact on survival rate in salivary duct carcinoma. Materials & Methods: We studied 33 patients with salivary gland cancer who were available for histologic specimens. We examined the expression of PD-L1 in the tissues and analyzed the association with the survival rate and the association with various clinical parameters. Results: According to this study and review of similar studies, we discovered that the expression of PD-L1 in salivary duct carcinoma was lower than other types of cancers. The impact of PD-L1 on survival rate also showed inconsistency in salivary duct carcinoma. Conclusion: Immunotherapy by PD-1/PD-L1 checkpoint blockade in salivary duct carcinoma needs further evaluation for clinical application.","PeriodicalId":336823,"journal":{"name":"Korean Society for Head and Neck Oncology","volume":"464 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115731783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-30DOI: 10.21593/KJHNO/2019.35.1.45
Geonho Lee, Ho-Ryun Won, B. Koo, J. Chang
Osseous choristoma is a rare, benign proliferative osseous lesion, which is defined as the growth of normal tissue in an abnormal location. The etiopathogenesis for its formation is unknown, but various hypotheses have been proposed. Treatment of choice is en-bloc resection, and no recurrence has been reported. Here, we report the two cases of osseous choristoma, presented with a mass on the base of the tongue with/without globus symptom and were treated with surgical excision.
{"title":"Two cases of osseous choristoma on tongue base","authors":"Geonho Lee, Ho-Ryun Won, B. Koo, J. Chang","doi":"10.21593/KJHNO/2019.35.1.45","DOIUrl":"https://doi.org/10.21593/KJHNO/2019.35.1.45","url":null,"abstract":"Osseous choristoma is a rare, benign proliferative osseous lesion, which is defined as the growth of normal tissue in an abnormal location. The etiopathogenesis for its formation is unknown, but various hypotheses have been proposed. Treatment of choice is en-bloc resection, and no recurrence has been reported. Here, we report the two cases of osseous choristoma, presented with a mass on the base of the tongue with/without globus symptom and were treated with surgical excision.","PeriodicalId":336823,"journal":{"name":"Korean Society for Head and Neck Oncology","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115785292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-30DOI: 10.21593/KJHNO/2019.35.1.1
J. Kim
In head and neck reconstruction, microsurgeons are faced with various demands, such as thin resurfacing, or three-dimensional reconstruction, and therefore, conventional flap as well as perforator flaps are all useful for the functional and aesthetic reconstruction successfully. Among perforator flaps, the pros and cons of anterolateral thigh perforator flap(ALTp) and thoracodorsal perforator flap(TAp) is compared and selected depending on the surgeon’s preference, recipient site condition or patient status. Both flaps can be elevated in a chimeric pattern by combining different aspects of tissue components. Customized or tailored reconstruction as well as 3 dimensional reconstructions are all available with perforator flaps and it is useful in head and neck reconstruction. The most outstanding update in head and neck reconstruction is the perforator based island flap (PBIF) compared to conventional flaps. The conventional local flap has evolved on behalf of the perforator concept and its design becomes more flexible and freestyle with less limitations. Actually, random pattern flap is now a misnomer and most conventional local flaps turn into PBIFs. Finally we can say all conventional donor site becomes universal, depending on the surgeons’ preference or idea. Moreover, there is no more “flap of choice” and postoperative results are quite variable by surgeons’ ability. Operative procedures and plans are very flexible to freestyle flap. With all these advantages, surgeons should be armed with both conventional and perforator concepts for solving any defects or problems.
{"title":"Contribution of Perforator Flaps in the Flap Selection for Head and Neck Reconstruction","authors":"J. Kim","doi":"10.21593/KJHNO/2019.35.1.1","DOIUrl":"https://doi.org/10.21593/KJHNO/2019.35.1.1","url":null,"abstract":"In head and neck reconstruction, microsurgeons are faced with various demands, such as thin resurfacing, or three-dimensional reconstruction, and therefore, conventional flap as well as perforator flaps are all useful for the functional and aesthetic reconstruction successfully. Among perforator flaps, the pros and cons of anterolateral thigh perforator flap(ALTp) and thoracodorsal perforator flap(TAp) is compared and selected depending on the surgeon’s preference, recipient site condition or patient status. Both flaps can be elevated in a chimeric pattern by combining different aspects of tissue components. Customized or tailored reconstruction as well as 3 dimensional reconstructions are all available with perforator flaps and it is useful in head and neck reconstruction. The most outstanding update in head and neck reconstruction is the perforator based island flap (PBIF) compared to conventional flaps. The conventional local flap has evolved on behalf of the perforator concept and its design becomes more flexible and freestyle with less limitations. Actually, random pattern flap is now a misnomer and most conventional local flaps turn into PBIFs. Finally we can say all conventional donor site becomes universal, depending on the surgeons’ preference or idea. Moreover, there is no more “flap of choice” and postoperative results are quite variable by surgeons’ ability. Operative procedures and plans are very flexible to freestyle flap. With all these advantages, surgeons should be armed with both conventional and perforator concepts for solving any defects or problems.","PeriodicalId":336823,"journal":{"name":"Korean Society for Head and Neck Oncology","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129906273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-30DOI: 10.21593/KJHNO/2019.35.1.37
Seok Jung Hong, Mi Ji Lee, Seung Woo Kim
Angioimmunoblastic T-cell lymphoma (AITL) is a rare subtype of malignant lymphoma (ML), accounting for only 1 to 2% of all non-Hodgkin’s lymphoma (NHL). Although ML of the parotid gland is rare, the majority are B-cell types. The AITL occurring synchronously in the parotid gland and lateral neck has not been reported earlier. It is classified as a high-grade malignancy with aggressive clinical features, and the prognosis is worse than any other type of NHL. We recently encountered a 72-year-old man with multiple mass on the ipsilateral parotid tail and lateral neck, and he was finally diagnosed as AITL. We report the unique and rare disease entity with a brief literature review.
{"title":"A Case of Angioimmunoblastic T-cell Lymphoma Involving the Ipsilateral Parotid and Lateral Neck","authors":"Seok Jung Hong, Mi Ji Lee, Seung Woo Kim","doi":"10.21593/KJHNO/2019.35.1.37","DOIUrl":"https://doi.org/10.21593/KJHNO/2019.35.1.37","url":null,"abstract":"Angioimmunoblastic T-cell lymphoma (AITL) is a rare subtype of malignant lymphoma (ML), accounting for only 1 to 2% of all non-Hodgkin’s lymphoma (NHL). Although ML of the parotid gland is rare, the majority are B-cell types. The AITL occurring synchronously in the parotid gland and lateral neck has not been reported earlier. It is classified as a high-grade malignancy with aggressive clinical features, and the prognosis is worse than any other type of NHL. We recently encountered a 72-year-old man with multiple mass on the ipsilateral parotid tail and lateral neck, and he was finally diagnosed as AITL. We report the unique and rare disease entity with a brief literature review.","PeriodicalId":336823,"journal":{"name":"Korean Society for Head and Neck Oncology","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132714000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-30DOI: 10.21593/KJHNO/2018.34.2.69
Ji Hoon Park, B. Lee, Jong Kyu Lee, S. Jang, Jin Hwan Kim, Jung Won Kim, Dong Jin Lee
{"title":"A case of cavernous lymphangioma causing shoulder pain","authors":"Ji Hoon Park, B. Lee, Jong Kyu Lee, S. Jang, Jin Hwan Kim, Jung Won Kim, Dong Jin Lee","doi":"10.21593/KJHNO/2018.34.2.69","DOIUrl":"https://doi.org/10.21593/KJHNO/2018.34.2.69","url":null,"abstract":"","PeriodicalId":336823,"journal":{"name":"Korean Society for Head and Neck Oncology","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123089282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-30DOI: 10.21593/kjhno/2018.34.2.89
Soyeon Yoon, Mijoo Kim, Minbum Kim, H. Hong, K. Song
{"title":"A case of nasopharyngeal mucoepidermoid carcinoma in a 5 year-old female patient","authors":"Soyeon Yoon, Mijoo Kim, Minbum Kim, H. Hong, K. Song","doi":"10.21593/kjhno/2018.34.2.89","DOIUrl":"https://doi.org/10.21593/kjhno/2018.34.2.89","url":null,"abstract":"","PeriodicalId":336823,"journal":{"name":"Korean Society for Head and Neck Oncology","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131531329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-30DOI: 10.21593/KJHNO/2018.34.2.85
Sung Hwan Lim, M. A. Kim, Seung Woo Kim
{"title":"A Case of Neurogenic Tumor-like Cervical Arteriovenous Malformation","authors":"Sung Hwan Lim, M. A. Kim, Seung Woo Kim","doi":"10.21593/KJHNO/2018.34.2.85","DOIUrl":"https://doi.org/10.21593/KJHNO/2018.34.2.85","url":null,"abstract":"","PeriodicalId":336823,"journal":{"name":"Korean Society for Head and Neck Oncology","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127914170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-30DOI: 10.21593/kjhno/2018.34.2.53
Eunji Kim, K. Hong, Y. Hong
{"title":"Nasopharyngeal cancer found after treatment of unknown primary cancer in the head and neck","authors":"Eunji Kim, K. Hong, Y. Hong","doi":"10.21593/kjhno/2018.34.2.53","DOIUrl":"https://doi.org/10.21593/kjhno/2018.34.2.53","url":null,"abstract":"","PeriodicalId":336823,"journal":{"name":"Korean Society for Head and Neck Oncology","volume":"49 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132942477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-30DOI: 10.21593/kjhno/2018.34.2.73
T. Kang, H. Kim, Jae Gu Kim, K. Lee, D. Lee
Accepted : September 4, 2018 : October 2, 2018(1차) / October 18, 2018(2차) October 19, 2018(3차) : October 22, 2018 +Corresponding author: Dong Hoon Lee, MD, PhD Department of Otolaryngology-Head and Neck Surgery Chonnam National University Medical School and Hwasun Hospital, 160 Ilsimri, Hwasun, Jeonnam, South Korea 519-809 Tel: +82-61-379-8190, Fax: +82-61-379-7761 E-mail: leen3l@hanmail.net 대한두경부종양학회지, 제34권 제2호, 2018. pp.73-76 Korean Journal of Head & Neck Oncology, Vol.34, No.2 https://doi.org/10.21593/kjhno/2018.34.2.73 ISSN 1229-5183(Print) / ISSN 2586-2553(Online)
{"title":"IgG4-related chronic sclerosing sialadenitis in both submandibular glands that developed at intervals of months","authors":"T. Kang, H. Kim, Jae Gu Kim, K. Lee, D. Lee","doi":"10.21593/kjhno/2018.34.2.73","DOIUrl":"https://doi.org/10.21593/kjhno/2018.34.2.73","url":null,"abstract":"Accepted : September 4, 2018 : October 2, 2018(1차) / October 18, 2018(2차) October 19, 2018(3차) : October 22, 2018 +Corresponding author: Dong Hoon Lee, MD, PhD Department of Otolaryngology-Head and Neck Surgery Chonnam National University Medical School and Hwasun Hospital, 160 Ilsimri, Hwasun, Jeonnam, South Korea 519-809 Tel: +82-61-379-8190, Fax: +82-61-379-7761 E-mail: leen3l@hanmail.net 대한두경부종양학회지, 제34권 제2호, 2018. pp.73-76 Korean Journal of Head & Neck Oncology, Vol.34, No.2 https://doi.org/10.21593/kjhno/2018.34.2.73 ISSN 1229-5183(Print) / ISSN 2586-2553(Online)","PeriodicalId":336823,"journal":{"name":"Korean Society for Head and Neck Oncology","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114895532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-30DOI: 10.21593/KJHNO/2018.34.2.11
S. Jin, Jae-Gu Kim, K. Park, I. Chung, W. Chung, Dong‐Hoon Lee, Joon-Kyoo Lee, S. Lim, T. Yoon
{"title":"The treatment outcome of T2 laryngeal squamous cell carcinoma in one institution with long term follow-up: Radiotherapy alone vs Chemoradiotherapy","authors":"S. Jin, Jae-Gu Kim, K. Park, I. Chung, W. Chung, Dong‐Hoon Lee, Joon-Kyoo Lee, S. Lim, T. Yoon","doi":"10.21593/KJHNO/2018.34.2.11","DOIUrl":"https://doi.org/10.21593/KJHNO/2018.34.2.11","url":null,"abstract":"","PeriodicalId":336823,"journal":{"name":"Korean Society for Head and Neck Oncology","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121800077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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