CHILD`S HEALTH最新文献

{"title":"Rehabilitation of children with Lyme arthritis","authors":"S. Nykytyuk, S. Levenets, S. Klymnyuk, L. Martynyuk, D.S. Pyvovarchuk, O.B. Dyakiv, G. Gabor","doi":"10.22141/2224-0551.18.4.2023.1601","DOIUrl":"https://doi.org/10.22141/2224-0551.18.4.2023.1601","url":null,"abstract":"Background. Lyme disease is a common tick-borne infection. Untimely diagnosis and treatment lead to the chronicity of the process with the development of late lesions of various systems and organs and possible disability. The purpose of the study was to develop a program of rehabilitation measures for children with Lyme disease. Material and methods. The research was conducted on the basis of the Ternopil Regional Children’s Hospital. Twenty children, residents of the Ternopil region, who applied to the Ternopil Regio­nal Children’s Hospital for tick bites and, as a result, diagnosed Lyme arthritis, took part in the study. To assess the severity of pain, we used scales and questionnaires for the diagnosis of DN4 neuropathic pain. Laboratory and instrumental studies were performed such as evaluation of the level of malondialdehyde, diene conjugates, superoxide dismutase. Results. Clinical examination of tick-affected children with Lyme disease showed that the most common primary clinical manifestation is a typical skin lesion — erythema migrans. In case of arthritis, all children notice inflammatory changes and pain in the joints. As a result of the conducted studies, the activation of peroxidation in children with Lyme disease was detected (an increase in the level of malondialdehyde and a decrease in superoxide dismutase, diene conjugates). It was shown that combined therapy with the use of magnetic laser therapy leads to the normalization of lipid peroxidation. Conclusions. All children with Lyme arthritis have a pain syndrome of varying severity. In patients with Lyme disease, there is an increase in the activity of lipid peroxidation and a decrease in the functional capacity of the antioxidant defense system. Children who underwent traditional treatment for Lyme arthritis reported a partial normalization of lipid peroxidation as evidenced by a significantly decreased level of diene conjugates compared to controls. In the group of patients who underwent combined treatment for Lyme arthritis (antibacterial therapy + magnetic laser therapy), the activity of antioxidant defense was normalized. Combination of magnetic laser therapy with antibacterial therapy demonstrates an improvement of pain status and faster rehabilitation of children.","PeriodicalId":338009,"journal":{"name":"CHILD`S HEALTH","volume":"138 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127522418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of single-nucleotide variants of the orsomucoid-1-like protein 3 gene with phenotypes of atopic march in children","authors":"V. Dytiatkovskyi","doi":"10.22141/2224-0551.18.3.2023.1586","DOIUrl":"https://doi.org/10.22141/2224-0551.18.3.2023.1586","url":null,"abstract":"Background. The problem of atopic march (AM), namely its progression from monoorganic phenotypes of atopic dermatitis (AD), allergic rhinitis/rhinoconjunctivitis (AR/ARC), bronchial asthma (BA) to their multiorgan combinations, is one of the biggest in the modern pediatrics. One of the most important causes for the development of these pathologies are single nucleotide variants (SNV) of the causative genes, orsomucoid-1-like protein 3 (ORMDL3), in particular rs_7216389 ORMDL3. The roles of T- and C-alleles in relation to monoorganic and polyorganic AM phenotypes have not been sufficiently studied. The objective was to study associations of the SNVs rs_7216389 ORMDL3 in the development of different AM phenotypes in children. Materials and methods. There were 293 children recruited into the main group and 105 controls aged 3 to 18 years. Children of the main group had monoorganic and polyorganic phenotypes of AM: AD, AR/ARC, BA, AD+AR/ARC, BA+AR/ARC, AD+AR/ARC+BA. Children of the control group suffered from organic and functional digestive pathology without clinical or paraclinical signs of AM. All children were genotyped for C/C, T/T, C/T variants of SNV rs_7216389 ORMDL3 by allelic discrimination method based on real time polymerase chain reaction with restriction fragment length polymorphism of the buccal swab obtained from each patient. Spearman’s correlation coefficient (rs) was used to determine associations; risks and protective effects were determined using logistic regression analysis by calculating odds ratios (OR) and 95% confidence intervals (CI). The results obtained were significant at p < 0.05 according to the Student’s test. Results. Risks and associations for the monoorganic AR/ARC phenotype: C/C SNV rs_7216389 ­ORMDL3: rs = 0.197, OR = 0.33 (95% CI 0.14–0.78, p < 0.05); T/T SNV rs_7216389 ORMDL3: rs = 0.246, OR = 3.21 (95% CI 1.57–6.59, p < 0.05). For the monoorganic BA phenotype: T/T SNV rs_7216389 ORMDL3: rs = 0.192, CI = 2.97 (95% CI 1.08–8.14, p < 0.05). For the polyorganic AD+AR/ARC phenotype: C/C SNV rs_7216389 ORMDL3: rs = 0.146, OR = 0.42 (95% CI 0.16–1.11, p = 0.05–0.1); T/T SNV rs_7216389 ­ORMDL3: rs = 0.265, OR = 3.64 (95% CI 1.62–8.18, p < 0.05). For the polyorganic BA+AR/ARC phenotype: C/C SNV rs_7216389 ORMDL3: rs = 0.163, OR = 0.42 (95% CI 0.19–0.93, p < 0.05); T/T SNV rs_7216389 ORMDL3: rs = 0.255, OR = 3.34 (95% CI 1.63–6.82, p < 0.01). The C/T SNV rs7216389 ORMDL3 genotype did not reveal significant associations or impact on the development of any AM phenotypes in children. Conclusions. The T-allele SNV rs7216389 ORMDL3 has an inductive impact on the development of AM in children — the homozygous T/T genotype of SNV rs7216389 ORMDL3 is significantly associated with and increases the risk of developing the monoorganic AR/ARC and BA phenotypes, as well as polyorganic AD+AR/ARC and BA+AR/ARC phenotypes. The C-allele SNV rs7216389 ORMDL3 has a protective impact on the development of AM in children — the homozygous ge","PeriodicalId":338009,"journal":{"name":"CHILD`S HEALTH","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121684976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of dental caries in pediatric patients with atopic dermatitis","authors":"T. Volosovets, I. Dikova, O. Mozyrska, N. Slyusar","doi":"10.22141/2224-0551.18.3.2023.1583","DOIUrl":"https://doi.org/10.22141/2224-0551.18.3.2023.1583","url":null,"abstract":"Background. Children with atopic dermatitis may be at increased risk of developing dental caries. This problem is poorly understood and needs attention. The aim of this study was to investigate the oral health status of children and adolescents with atopic dermatitis. Materials and methods. One hundred children with atopic dermatitis aged 2 to 17 years, median of 6 [3.5; 10], and 103 children without atopic dermatitis, median age 7 [5; 12.5] years, were included in the study. Clinical parameters included age, sex, age of onset and severity of atopic dermatitis according to the SCORing AD index (SCORAD). Patients with at least one type of caries at any stage of progression (from white spots to carious lesions with pulpal damage) were included in the caries group. The risk of caries in the atopic dermatitis group and in healthy children, and the significance of the presence of asthma and allergic rhinitis for the development of caries were evaluated using the odds ratio (OR) with a 95% confidence interval (CI). Results were considered statistically significant at the p < 0.05 level. Results. Caries was detected in 46 % of children with atopic dermatitis and 22 % controls (OR = 2.9630, CI 1.6131–5.4424, p = 0.0005). In the group of allergic rhinitis, 24 patients were found to have caries, and among those without allergic rhinitis, 22 children had caries. It was found that patients with concomitant allergic rhinitis were significantly more likely to develop caries (OR = 3.4406, CI 1.4693–8.0563, p = 0.0044). No such significance was found depending on the presence of asthma (OR = 1.3986, CI 0.4913–3.9814, p = 0.5). Conclusions. Children with atopic dermatitis have a significantly higher risk of dental caries than healthy children. Based on the results of our study, clinicians should be aware of dental manifestations in patients with atopic dermatitis and recommend regular dental examinations for early caries detection.","PeriodicalId":338009,"journal":{"name":"CHILD`S HEALTH","volume":"93 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117343825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of rhinomanometry in evaluating the effectiveness of laser surgical treatment in children with chronic hypertrophic rhinitis","authors":"D.F. Fuculița","doi":"10.22141/2224-0551.18.3.2023.1580","DOIUrl":"https://doi.org/10.22141/2224-0551.18.3.2023.1580","url":null,"abstract":"Background. Rhinomanometry is an objective way of assessing nasal patency. Due to advances in technology and the use of microcomputers connected to measuring instruments, the use of this approach has increased. Rhinomanometry evaluates nasal resistance by measuring airflow and transnasal pressure gradient. With the help of this examination, the presence of a nasal respiratory obstruction is detected, and it is evaluated which nosological structure continuously causes it, in this case the hypertrophy of the inferior nasal turbinates. The purpose of the research is to evaluate the effectiveness of the functional examination such as the anterior rhinomanometry in monitoring the results of laser surgical treatment in children with chronic hypertrophic rhinitis. Materials and methods. The given study was carried out in the pediatric otorhinolaryngology clinic of the Emilian Coţaga Republican Children’s Clinical Hospital. The research involved a group of 120 children with hypertrophic chronic rhinitis, aged between 8–17 years, divided into three groups of 40 children each, treated surgically by 3 techniques: group 1 — cauterization of the inferior nasal turbinates with bipolar forceps, group 2 — shaver mucotomy and group 3 — diode laser surgery. In all patients, rhinomanometry was performed as an objective preoperative and postoperative examination on the 7th day, after one month, one year and in 12 months. Results. The analysis of the functional examination results demonstrates that the surgical interventions had a beneficial effect in terms of the recovery of the space parameters of the nasal cavities. A more pronounced improvement of the endonasal architectural indices is determined in group 3 where the diode laser surgical technique was used compared to group 2 — only shaver mucotomy and group 1 where the standard surgical technique of cauterization with bipolar forceps was practiced. Conclusions. The functional rhinomanometric results were statistically different after the surgical treatment in all study groups that indicates an important diagnostic value of this examination in the monitoring of postoperative dynamics.","PeriodicalId":338009,"journal":{"name":"CHILD`S HEALTH","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120990171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prediction of the chronicity of inflammatory diseases of the urinary system in children","authors":"H. O. Lezhenko, N. A. Zakharchenko","doi":"10.22141/2224-0551.18.3.2023.1582","DOIUrl":"https://doi.org/10.22141/2224-0551.18.3.2023.1582","url":null,"abstract":"Background. The purpose was stratification of factors that lead to the chronicity of inflammatory diseases of the urinary system in children, as well as creation of a mathematical model for predicting their course. Materials and methods. The research group consisted of 97 children (average age — 10.0 ± 1.3 years). The main group was divided into subgroups: the first one — 43 children with acute urinary tract infections (UTIs), the second one — 34 patients with chronic UTIs. The control group consisted of 20 conditionally healthy children. The content of 1,25(OH)2D3, vitamin D-binding protein, inducible nitric oxide synthase (NOS2), cystatin C, cathelicidin, hepcidin, lactoferrin, interleukins 6, 15 was investigated by immunoenzymatic analysis. The impact of factor characteristics on the process of UTI chronicity was evaluated using factor and cluster analyses. A logistic regression equation was used to predict the probability of developing chronic UTIs. The quality of the constructed model was assessed by its sensitivity and specificity, and receiver operator characteristic (ROC) analysis was also used. Results. It was found that 6 factors had the greatest significance: the factor of functional disorders of the urinary tract, the factor of comorbid conditions, the protective factor, the immune factor, chronic foci of the disease, and the NOS2 factor. According to the results of logistic regression, the model for predicting the probability of developing chronic UTI in children had the form of an equation that included 6 variables (early manifestation of the disease, vitamin D level, vesicoureteral reflux, dysmetabolic nephropathy, neurogenic bladder, UTI in the mother in childhood). The classification ability of the model was determined based on the data of the training sample and was 75.0 %. The sensitivity of the model was 78.3 %, and the specificity was 76.5 %. The area under the ROC curve that corresponded to our mathematical model was equal to 0.776. The Gini index was 55.2 %, which corresponds to the good quality of the model. Conclusions. The process of chronicity of the inflammatory process in the urinary system in children occurs under the conditions of the interaction of some pathological factors. The leading risk factors for the chronicity of the inflammatory process are the presence of functional disorders of the urinary tract, early manifestation of the disease, the level of vitamin D, intestinal dysfunction, and the presence of UTI in the mother in childhood.","PeriodicalId":338009,"journal":{"name":"CHILD`S HEALTH","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116856514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Congenital heart defect — aortopulmonary window: diagnostic features in infants","authors":"A. Malska, O. Kuryliak, T. Yalynska, O. V. Stogova","doi":"10.22141/2224-0551.18.3.2023.1591","DOIUrl":"https://doi.org/10.22141/2224-0551.18.3.2023.1591","url":null,"abstract":"Aortopulmonary window (APW) is a congenital heart defect characterized by the presence of an abnormal connection between the pulmonary artery and the proximal part of the aortic arch directly above the level of the semilunar valves. It is one of the rarest cardiac defects (frequency of 0.2–0.6 %). APW occurs as an isolated cardiac lesion or in association with other anomalies such as coarctation of the aorta, interrupted aortic arch, tetra­logy of Fallot, and atrial septal defect or patent ductus arteriosus. Treatment of APW comprises surgical correction of the defect, which should be performed immediately after diagnosis in order to prevent the development of pulmonary hypertension. Postoperative complications after surgical correction of APW occur rarely and depend on the association of this defect with other congenital heart defects, especially with an interrupted aortic arch. In this article, we present a retrospective analysis of patients with APW for 2003–2022, who were examined at the Lviv Regional Children’s Hospital OHMATDYT, and 2 clinical cases of APW in 2- and 10-month-old boys.","PeriodicalId":338009,"journal":{"name":"CHILD`S HEALTH","volume":"115 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123250259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of vitamin D in the course of SARS-CoV-2 infection and long COVID in children (literature review)","authors":"L. Volianska, E. Burbela, T. Kosovska, V.O. Perestyuk, O. Boyarchuk","doi":"10.22141/2224-0551.18.3.2023.1590","DOIUrl":"https://doi.org/10.22141/2224-0551.18.3.2023.1590","url":null,"abstract":"Long-term observation of the SARS-CoV-2 pandemic in the pediatric population revealed the presence of persistent symptoms in 1 : 4 to 1 : 10 children four or more weeks after the onset of this infection. The question about the role of vitamin D in the course of COVID-19 and the development of long-term health conditions is still debatable. The purpose of this review is to generalize and clarify the effect of vitamin D on the course of ­COVID-19 and the post-COVID period in children. Electronic search for scientific publications was done in the PubMed, Scopus, ResearchGate, Wiley Online Library and Google Scholar databases from 2019 to February 2023. Analysis of studies on COVID-19, the post-COVID period, and the impact of hypovitaminosis D on their course attests to the ambiguity of published results in the pediatric cohort. A number of resear­chers have linked vitamin D deficiency to higher mortality, higher hospitalization rates, and longer hospital stays. Hypovitaminosis D impairs the functioning of the immune system in an organism infected with the pandemic coronavirus, which increases the risk of severe course and mortality. But this hypothesis still needs in-depth study to understand the essence of the effect of vitamin D supplementation on the course of the coronavirus infection and long COVID. The hypothesis about the relationship between hypovitaminosis D and immunosuppression during infection with a pandemic coronavirus and its potential role in the formation of long-term health conditions after acute COVID-19 is still under permanent study.","PeriodicalId":338009,"journal":{"name":"CHILD`S HEALTH","volume":"129 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129709180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic tonsillitis in adolescents: clinical features and the role of ultrasound diagnosis in the northern region of Ukraine","authors":"Yuliia A Manko, O. I. Smiian, A. Loboda, S. V. Popov, P. I. Sichnenko, O. Vasylieva, K. Smiian, I. Vysotsky, T. Aleksakhina","doi":"10.22141/2224-0551.18.3.2023.1579","DOIUrl":"https://doi.org/10.22141/2224-0551.18.3.2023.1579","url":null,"abstract":"Background. Chronic tonsillitis is the most common disease among children and adolescents in the structure of pathology of the ENT organs. Untimely diagnosis and irrational treatment lead to decompensation of chronic tonsillitis and the development of lesions of many organs and systems of the child’s body of tonsillogenic origin. The aim of the work was to study the clinical features and ultrasound changes of the palatine tonsils in adolescents with chronic tonsillitis. Materials and methods. We have examined 47 children aged 13 to 17 years suffering from chronic tonsillitis: group I — 27 patients with compensated chronic tonsillitis, group II — 20 patients suffering from decompensated chronic tonsillitis. The control group consisted of 16 practically healthy children, representative in terms of age and gender. We used clinical methods, ultrasonography of the palatine tonsils, and statistical methods. The study was approved by the Institutional Bioethics Committee and it conforms to the principles outlined in the Declaration of Helsinki. Results. According to the results of an ultrasound examination of the palatine tonsils in children with chronic tonsillitis, the main changes were an increase in their transverse dimensions by more than 15 mm, deepening of lacunae, thickening of the capsule, fibrous changes. In addition, in patients with tonsillogenic lesions of the cardiovascular system and a decompensated form of chronic tonsillitis, the pathological signs of the disease according to ultrasound were more significant and were manifested by unclear contours, increased echogenicity, heterogeneous hyperechoic structure, diffuse fibrous and cystic changes of the palatine tonsils. Conclusions. Ultrasonography of the palatine tonsils is a non-invasive, painless, accessible and informative method for studying the structure of the tonsils in normal and pathological conditions. It allows for a more thorough assessment of their changes in compensated and decompensated forms of chronic tonsillitis.","PeriodicalId":338009,"journal":{"name":"CHILD`S HEALTH","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129312359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parental presence in the pediatric intensive care unit","authors":"V. Snisar, S. Egorov","doi":"10.22141/2224-0551.18.3.2023.1589","DOIUrl":"https://doi.org/10.22141/2224-0551.18.3.2023.1589","url":null,"abstract":"Background. Currently, parental presence at the bedside of critically ill children in the pediatric intensive care unit (PICU) is a necessary family-oriented condition. In the published sources, there is enough evidence that shows the special emotional state of parents, their complex interactions with the medical staff of the PICU, as well as the attitude of doctors and nurses to parental presence in the department, especially during the manipulation on patients. In Ukraine, only in some pediatric medical centers parents were allowed to visit their children in the PICU, but permanent stay at the patient’s bedside was not allowed. In 2016, the order of the Ministry of Health of Ukraine No. 592 “On the approval of the Procedure for the admission of visitors to patients undergoing inpatient treatment in the intensive care unit” determined the procedure and rules for the admission of visitors to a patient who was in the intensive care unit. However, this Order established only rules for the admission of visitors to adult patients undergoing inpatient treatment in the intensive care units. The purpose of the work is to consider various strategic directions for ensuring access of parents to their sick children in the PICU and try to adapt some issues to the current state of our pediatric intensive care. Results. The article discusses issues such as the ethical and practical situation regarding the visiting and presence of parents at the bedside of a critically ill child in the PICU. The concepts of “visiting” or “presence” are considered, and the conditions are defined when parents can only visit, and when they can stay at the bedside of a sick child for a long time; the possibility of their presence during manipulations and procedures; the role of doctors and nurses in communicating with parents in the intensive care unit and the impact on their emotional state. Conclusions. Given the real need for parents to be present and visit their children in the intensive care unit, we must be careful and prudent in making this decision. You can face a lot of problems and inconveniences, but you must strive to change the established principles, because the presence of fa­mily members, their participation in providing assistance to children will improve the psychological environment in the intensive care unit and increase the humaneness of the work of its medical staff.","PeriodicalId":338009,"journal":{"name":"CHILD`S HEALTH","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131446404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Healthcare-associated infections in children in Ukraine during 2009–2021","authors":"O. Korniychuk, I. Tymchuk, S.Y. Pavliy, Y. Konechnyi","doi":"10.22141/2224-0551.18.3.2023.1588","DOIUrl":"https://doi.org/10.22141/2224-0551.18.3.2023.1588","url":null,"abstract":"Background. Healthcare-associated infections (HCAIs) now include the development of infectious processes in various organ systems of patients and at hospitals of different work directions. It is believed that HCAIs are infections that first occur 48 hours or later after hospitalization or 30 days after receiving medical care. The aim of our research was a retrospective analysis of the incidence of HCAIs among children in Ukraine during 2009–2021. Materials and methods. Statistical analysis of the prevalence of registered cases of HCAIs in Ukraine for 2009–2021, according to the Center for Public Health of the Ministry of Health of Ukraine. Results. On average, 966 ± 489 cases of HCAIs were registered annually in Ukraine among children of various ages. According to the age distribution, the number of annual cases of HCAIs among newborns of up to 1 month of age averaged 65.8 %, for those aged 1 month to 1 year — 5.9 %, from 1 to 17 years — 28.3 %. According to the nosological structure of HCAIs, infections of certain conditions occurring in the perinatal period prevailed among children. On average, the number of such diseases for 2010–2021 was 49.5 ± 7.5 % (among children 0–17 years old) and 13.8 % of the total cases of HCAIs in Ukraine. Conclusions. In recent years, there has been an underestimation of HCAI cases in Ukraine among adult patients and children. Nevertheless, indicators provided by institutions of some regions (Odesa and Kyiv regions) make it possible, with a certain degree of probability, to get an idea of the structure of HCAI incidence in the country. According to the age structure, HCAIs in children (0–17 years) for 2009–2021 accounted for 22.06 % of the total number of HCAIs. Most cases during the specified period were recorded among newborns, 65.8 % of all children with HCAIs. Therefore, the primary efforts should be aimed at reducing HCAIs among newborns.","PeriodicalId":338009,"journal":{"name":"CHILD`S HEALTH","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114845018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}