Pub Date : 2023-06-01DOI: 10.20862/0042-4676-2023-104-1-21-29
A. Petraikin, Z. R. Artyukova, N. Kudryavtsev, D. Semenov, A. Smorchkova, S. S. Repin, E. Akhmad, F. A. Petriaikin, L. A. Nisovtsova, A. V. Vladzimirskyy
Objective: to conduct the study of age distribution of bone mineral density (BMD) by the database of dualenergy X-ray absorptiometry (DXA) and to compare it with datа of population NHANES study. Material and methods. We used data from the densitometry of three-zone (total hip (TH), femoral neck (FN), and lumbar spine) measured by DXA from two outpatient clinics. The obtained data were compared with NHANES III for TH and FN and with NHANES 2005-08 for lumbar spine. The BMD value was corrected with the calibration coefficient for each DXA scanner. Adjustments were also made for the population distribution by sex and age. Results. Compared with NHANES for FN and TH, the obtained BMD values were significantly decreased for patients aged less than 50 years (men and women). The BMD values for FN and TH were unsignificantly decreased in men older 50 years. In women older 50 years unsignificantly decreased BMD values for FN and a significantly increased BMD values for TH were observed. The BMD values were decreased for lumbar spine in men and women throughout this age interval (more than 50 years old). Conclusion. The population BMD distribution in men and women was assessed by DXA method. The obtained dependence of the BMD for FN in women older 50 years was in good agreement with the results given by Russian and foreign authors.
目的:利用双能x线骨密度仪(DXA)数据库研究骨密度(BMD)的年龄分布,并与人口NHANES研究数据进行比较。材料和方法。我们使用了来自两个门诊诊所的DXA测量的三个区域(全髋关节(TH),股骨颈(FN)和腰椎)的密度测量数据。将获得的数据与NHANES III (TH和FN)和NHANES 2005-08(腰椎)进行比较。用每个DXA扫描仪的校准系数校正BMD值。按性别和年龄划分的人口分布也作了调整。结果。与FN和TH的NHANES相比,年龄小于50岁的患者(男性和女性)获得的BMD值显着降低。在50岁以上的男性中,FN和TH的骨密度值没有明显下降。在50岁以上的女性中,观察到FN骨密度值无显著下降,而TH骨密度值显著增加。在这个年龄段(超过50岁),男性和女性腰椎的骨密度值都有所下降。结论。采用DXA法评估男女人群骨密度分布。所获得的骨密度对50岁以上妇女FN的依赖性与俄罗斯和国外作者给出的结果很好地一致。
{"title":"Analysis of Age Distribution of Bone Mineral Density by Dual-Energy X-Ray Absorptiometry","authors":"A. Petraikin, Z. R. Artyukova, N. Kudryavtsev, D. Semenov, A. Smorchkova, S. S. Repin, E. Akhmad, F. A. Petriaikin, L. A. Nisovtsova, A. V. Vladzimirskyy","doi":"10.20862/0042-4676-2023-104-1-21-29","DOIUrl":"https://doi.org/10.20862/0042-4676-2023-104-1-21-29","url":null,"abstract":"Objective: to conduct the study of age distribution of bone mineral density (BMD) by the database of dualenergy X-ray absorptiometry (DXA) and to compare it with datа of population NHANES study. Material and methods. We used data from the densitometry of three-zone (total hip (TH), femoral neck (FN), and lumbar spine) measured by DXA from two outpatient clinics. The obtained data were compared with NHANES III for TH and FN and with NHANES 2005-08 for lumbar spine. The BMD value was corrected with the calibration coefficient for each DXA scanner. Adjustments were also made for the population distribution by sex and age. Results. Compared with NHANES for FN and TH, the obtained BMD values were significantly decreased for patients aged less than 50 years (men and women). The BMD values for FN and TH were unsignificantly decreased in men older 50 years. In women older 50 years unsignificantly decreased BMD values for FN and a significantly increased BMD values for TH were observed. The BMD values were decreased for lumbar spine in men and women throughout this age interval (more than 50 years old). Conclusion. The population BMD distribution in men and women was assessed by DXA method. The obtained dependence of the BMD for FN in women older 50 years was in good agreement with the results given by Russian and foreign authors.","PeriodicalId":34090,"journal":{"name":"Vestnik rentgenologii i radiologii","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48295330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-27DOI: 10.20862/0042-4676-2022-103-4-6-88-93
Е. V. Meskikh, N. Nudnov, G. Z. Mukhutdinova, V. О. Vorob’eva
Will the detected lung foci in patients with a burdened oncological history (breast cancer) always be metastatic? In response to the question posed, we present a clinical case of pulmonary sarcoidosis mimicking the metastatic lesion of metaplastic breast cancer. And we remind of the need for a differential diagnosis, despite the oncological history of a patient and radiation diagnostics data.
{"title":"Rare Form of Breast Cancer and Lung Foci: Do We Always Have to Wait for Metastases?","authors":"Е. V. Meskikh, N. Nudnov, G. Z. Mukhutdinova, V. О. Vorob’eva","doi":"10.20862/0042-4676-2022-103-4-6-88-93","DOIUrl":"https://doi.org/10.20862/0042-4676-2022-103-4-6-88-93","url":null,"abstract":"Will the detected lung foci in patients with a burdened oncological history (breast cancer) always be metastatic? In response to the question posed, we present a clinical case of pulmonary sarcoidosis mimicking the metastatic lesion of metaplastic breast cancer. And we remind of the need for a differential diagnosis, despite the oncological history of a patient and radiation diagnostics data.","PeriodicalId":34090,"journal":{"name":"Vestnik rentgenologii i radiologii","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42034378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-27DOI: 10.20862/0042-4676-2022-103-4-6-101-107
I. I. Litovets, T. S. Litovets
Meningoencephalocele is a rare pathology. By origin, it can be congenital and acquired. As a rule, congenital menigoencephaloceles are combined with various congenital skull structure anomalies, and are rarely asymptomatic. This pathology is most often solitary, and cases of multiple meningoencephalocele in one patient are extremely rare. The presented clinical case demonstrates an accidental finding: an unusual variant of symmetrically located bilateral naso-orbital meningoencephalocele with asymptomatic course in a 17-year-old patient.
{"title":"A Rare Case of Asymptomatic Bilateral Naso-Orbital Meningoencephalocele","authors":"I. I. Litovets, T. S. Litovets","doi":"10.20862/0042-4676-2022-103-4-6-101-107","DOIUrl":"https://doi.org/10.20862/0042-4676-2022-103-4-6-101-107","url":null,"abstract":"Meningoencephalocele is a rare pathology. By origin, it can be congenital and acquired. As a rule, congenital menigoencephaloceles are combined with various congenital skull structure anomalies, and are rarely asymptomatic. This pathology is most often solitary, and cases of multiple meningoencephalocele in one patient are extremely rare. The presented clinical case demonstrates an accidental finding: an unusual variant of symmetrically located bilateral naso-orbital meningoencephalocele with asymptomatic course in a 17-year-old patient.","PeriodicalId":34090,"journal":{"name":"Vestnik rentgenologii i radiologii","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43940467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-27DOI: 10.20862/0042-4676-2022-103-4-6-94-100
E. Yelshibayeva, R. U. Kapi, D. Mardenkyzy, S. K. Gadylkan, M. M. Khoyshibay, A. N. Sapkina
Pancreatic adenocarcinoma is the most pervasive form of cancer with high mortality rates. Being obscure at the early stages, non-specific symptoms and their onset only in the late stages of the disease lead to detection of the III–IV stages cancer on initial diagnistics. Gastrointestinal stromal tumor (GIST) is an intramucosal tumor of gastrointestinal tract, which is a derivate of interstitial cells of Cajal. The unicity of the presented clinical case is the rareness of GIST, which was an incidental finding during diagnostics of pancreatic adenocarcinoma. Diagnosed by intravenous contrast computed tomography, synchronous pancreatic and duodenal double cancer was confirmed histologically after Whipple surgery. The opportunities of intravenous contrast computed tomography in diagnostics of synchronous cancer were demonstrated.
{"title":"Histologycally Confirmed Synchronous Pancreatic and Duodenal Double Cancer","authors":"E. Yelshibayeva, R. U. Kapi, D. Mardenkyzy, S. K. Gadylkan, M. M. Khoyshibay, A. N. Sapkina","doi":"10.20862/0042-4676-2022-103-4-6-94-100","DOIUrl":"https://doi.org/10.20862/0042-4676-2022-103-4-6-94-100","url":null,"abstract":"Pancreatic adenocarcinoma is the most pervasive form of cancer with high mortality rates. Being obscure at the early stages, non-specific symptoms and their onset only in the late stages of the disease lead to detection of the III–IV stages cancer on initial diagnistics. Gastrointestinal stromal tumor (GIST) is an intramucosal tumor of gastrointestinal tract, which is a derivate of interstitial cells of Cajal. The unicity of the presented clinical case is the rareness of GIST, which was an incidental finding during diagnostics of pancreatic adenocarcinoma. Diagnosed by intravenous contrast computed tomography, synchronous pancreatic and duodenal double cancer was confirmed histologically after Whipple surgery. The opportunities of intravenous contrast computed tomography in diagnostics of synchronous cancer were demonstrated.","PeriodicalId":34090,"journal":{"name":"Vestnik rentgenologii i radiologii","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43999645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-27DOI: 10.20862/0042-4676-2022-103-4-6-108-116
S. Mironov, V. Sergienko
Thyroid scintigraphy is a method that formed more than 60 years ago and retains its importance for the diagnosis and assessment of the risk of nodular malignancy. The review examines the use of the scintigraphic method in functional and metabolic assessment of nodular goiter. Prerequisites for functional thyroid nodes screening with short-lived 99mTc-pertechnetate are outlined. Information is provided on the principles of its preparation and pharmacokinetics, as well as variants of the thyroid nodes functional activity, their possible malignant potential and indications for metabolic screening. The characteristic of metabolic activity allows to assess the risk of functionally “cold” thyroid nodes malignancy. The main stages of the use of nonspecific tumorotropic radiopharmaceuticals, the mechanism of their accumulation and metabolism in the thyroid tumors, the possibilities of the differential diagnosis of various types of nodular formations are presented. Modern views on the diagnostic capabilities of two-phase scintigraphy with 99mTс-methylisobutylisonitrile are reflected taking into account the relationship of radiopharmaceuticals accumulation with factors of proliferative activity and ultrastructural cell types, a variant of oncocytic pathology and multidrug-resistant protein expression.
{"title":"Scintigraphy in Thyroid Nodular Pathology","authors":"S. Mironov, V. Sergienko","doi":"10.20862/0042-4676-2022-103-4-6-108-116","DOIUrl":"https://doi.org/10.20862/0042-4676-2022-103-4-6-108-116","url":null,"abstract":"Thyroid scintigraphy is a method that formed more than 60 years ago and retains its importance for the diagnosis and assessment of the risk of nodular malignancy. The review examines the use of the scintigraphic method in functional and metabolic assessment of nodular goiter. Prerequisites for functional thyroid nodes screening with short-lived 99mTc-pertechnetate are outlined. Information is provided on the principles of its preparation and pharmacokinetics, as well as variants of the thyroid nodes functional activity, their possible malignant potential and indications for metabolic screening. The characteristic of metabolic activity allows to assess the risk of functionally “cold” thyroid nodes malignancy. The main stages of the use of nonspecific tumorotropic radiopharmaceuticals, the mechanism of their accumulation and metabolism in the thyroid tumors, the possibilities of the differential diagnosis of various types of nodular formations are presented. Modern views on the diagnostic capabilities of two-phase scintigraphy with 99mTс-methylisobutylisonitrile are reflected taking into account the relationship of radiopharmaceuticals accumulation with factors of proliferative activity and ultrastructural cell types, a variant of oncocytic pathology and multidrug-resistant protein expression.","PeriodicalId":34090,"journal":{"name":"Vestnik rentgenologii i radiologii","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44647685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-26DOI: 10.20862/0042-4676-2022-103-4-6-28-35
Yulduz Khodjibekova, M. Khodjibekov, B. R. Akhmedov, A. Pattokhov, A. S. Nigmatdjanov
Objective: to determine the diagnostic significance of computed tomography texture analysis (CTTA) in differentiating head and neck tumors.Material and methods. The study included 118 patients aged from 4 to 80 years with a verified diagnosis of benign and malignant (37 and 81, respectively) head and neck tumors. CTTA was performed using the LIFEx program, version 6.30. Thirty eight (38) texture indices extracted from routine CT images were tested by regression analysis with creation of logistic texture models with associations of four indices as independent predictors.Results. The possibility of using derived models – probability textural indices for benign and malignant tumors differentiation was established: area under ROC-curve (AUC) 0.854 ± 0.035 (p < 0.001); for differentiation of locally spread from locally limited tumors: AUC 0.840 ± 0.049 (p < 0.001); for differentiation of moderately, poorly, and undifferentiated cancer (G2, G3, G4) from well-differentiated (G1) head and neck cancer: AUC 0.826 ± 0.085 (p < 0.001).Conclusion. CT images texture analysis allows to make non-invasive prognosis of benign or malignant nature of a visualized head and neck tumor, as well as to determine the extent and degree of tumor malignancy.
{"title":"Texture Analysis of CT Images in Head and Neck Tumors Differentiation","authors":"Yulduz Khodjibekova, M. Khodjibekov, B. R. Akhmedov, A. Pattokhov, A. S. Nigmatdjanov","doi":"10.20862/0042-4676-2022-103-4-6-28-35","DOIUrl":"https://doi.org/10.20862/0042-4676-2022-103-4-6-28-35","url":null,"abstract":"Objective: to determine the diagnostic significance of computed tomography texture analysis (CTTA) in differentiating head and neck tumors.Material and methods. The study included 118 patients aged from 4 to 80 years with a verified diagnosis of benign and malignant (37 and 81, respectively) head and neck tumors. CTTA was performed using the LIFEx program, version 6.30. Thirty eight (38) texture indices extracted from routine CT images were tested by regression analysis with creation of logistic texture models with associations of four indices as independent predictors.Results. The possibility of using derived models – probability textural indices for benign and malignant tumors differentiation was established: area under ROC-curve (AUC) 0.854 ± 0.035 (p < 0.001); for differentiation of locally spread from locally limited tumors: AUC 0.840 ± 0.049 (p < 0.001); for differentiation of moderately, poorly, and undifferentiated cancer (G2, G3, G4) from well-differentiated (G1) head and neck cancer: AUC 0.826 ± 0.085 (p < 0.001).Conclusion. CT images texture analysis allows to make non-invasive prognosis of benign or malignant nature of a visualized head and neck tumor, as well as to determine the extent and degree of tumor malignancy.","PeriodicalId":34090,"journal":{"name":"Vestnik rentgenologii i radiologii","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47622046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-26DOI: 10.20862/0042-4676-2022-103-4-6-78-87
А. D. Strutynskaya, M. Karnaushkina, L. I. Dvoretskiy, I. Tyurin
Objective: to study associations between laboratory and radiological biomarkers of COVID-19, to develop prognostic model of deterioration and lethal outcome in a patient with COVID-19.Material and methods. The study included 162 patients with COVID-19 stratified according to the presence or absence of deterioration during hospitalization. We evaluated chest computed tomography (CT) data, assessed empirically and using a semi-quantitative scale, blood cell counts and parameters of biochemical blood test. The predictive model was built using gradient boosting and artificial neural network with sigmoid activation function.Results. Both CT signs (crazy-paving pattern, bronchial dilatation inside a lesion, peripheral distribution of symptoms, absence of a predominant distribution pattern, lesion grade and extent), and most of laboratory markers were associated with deterioration and its criteria. The CT severity index correlated positively with the levels of leukocytes, neutrophils, urea, aspartate aminotransferase, lactate dehydrogenase, creatine phosphokinase, glucose, C-reactive protein, and negatively with the concentrations of albumin, calcium and the number of lymphocytes. Based on the results of the selection and training of classifying models, the optimal method for stratifying patients with COVID-19 on the basis of deterioration during hospitalization, the need for transfer to the intensive care unit, mechanical ventilation, and adverse outcome was gradient boosting.Conclusion. The prognostic model obtained in our study, based on a combination of radiological and laboratory parameters, makes it possible to predict the nature of COVID-19 course with high reliability.
{"title":"Prognostic Value of Radiological and Laboratory Biomarkers for Assessing Risk of Adverse Outcome in Patients with COVID-19","authors":"А. D. Strutynskaya, M. Karnaushkina, L. I. Dvoretskiy, I. Tyurin","doi":"10.20862/0042-4676-2022-103-4-6-78-87","DOIUrl":"https://doi.org/10.20862/0042-4676-2022-103-4-6-78-87","url":null,"abstract":"Objective: to study associations between laboratory and radiological biomarkers of COVID-19, to develop prognostic model of deterioration and lethal outcome in a patient with COVID-19.Material and methods. The study included 162 patients with COVID-19 stratified according to the presence or absence of deterioration during hospitalization. We evaluated chest computed tomography (CT) data, assessed empirically and using a semi-quantitative scale, blood cell counts and parameters of biochemical blood test. The predictive model was built using gradient boosting and artificial neural network with sigmoid activation function.Results. Both CT signs (crazy-paving pattern, bronchial dilatation inside a lesion, peripheral distribution of symptoms, absence of a predominant distribution pattern, lesion grade and extent), and most of laboratory markers were associated with deterioration and its criteria. The CT severity index correlated positively with the levels of leukocytes, neutrophils, urea, aspartate aminotransferase, lactate dehydrogenase, creatine phosphokinase, glucose, C-reactive protein, and negatively with the concentrations of albumin, calcium and the number of lymphocytes. Based on the results of the selection and training of classifying models, the optimal method for stratifying patients with COVID-19 on the basis of deterioration during hospitalization, the need for transfer to the intensive care unit, mechanical ventilation, and adverse outcome was gradient boosting.Conclusion. The prognostic model obtained in our study, based on a combination of radiological and laboratory parameters, makes it possible to predict the nature of COVID-19 course with high reliability.","PeriodicalId":34090,"journal":{"name":"Vestnik rentgenologii i radiologii","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44539183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-26DOI: 10.20862/0042-4676-2022-103-4-6-36-51
I. S. Gabdulganieva, N. R. Munirova, A. R. Zaripova, V. Anisimov
Objective: to study the computed tomography (CT) and magnetic resonance imaging (MRI) manifestations of rhinocerebral mucormycosis (RCM) in patients with diabetes mellitus and new coronavirus infection, to develop attentive attitude of radiologists for early detection of this pathology, rapid surgery and followup examinations.Material and methods. Totally 53 head (facial skull, soft facial tissues and brain) CT and MRI studies were performed in 13 patients with RCM. The number of CT and MRI studies varied from 1 to 9 per one patient, depending on the severity of his condition and clinical indications; the follow-up period was 1–4 months. All patients received surgical aid; diagnosis was verified by microscopy of surgical samples of excised necrotic tissues. A detailed descriptive analysis of pathological changes on CT and MRI characterizing RCM was carried out. The sequence of pathological signs manifestations was described, the prevalence of the lesion was estimated for planning the scope of surgical intervention. A comparative analysis of the identified RCM signs with the literature data was performed.Results. Lesions of the nasal cavity and paranasal sinuses in RCM were found in 100% of our observations, with approximately equal single and bilateral lesions of 54% and 46%, respectively. Lesions of the perimaxillar fatty tissue and pterygoid fossa were determined in 77% of patients, unilateral orbital lesions – in 23%, superior orbital vein and cavernous sinus thrombosis – in 31%, facial soft tissue lesion – in 15.5%, intracranial spread through the perineural spaces – in 7.7%, internal carotid artery arteritis – in 15.5%. Brain substance and meninges involvement in the pathological process was observed in the form of cerebritis in 23% of patients and meningitis in 46%. The formation of brain abscess was noted in follow up examinations in 15.5% of patients, skull bones osteomyelitis was diagnosed in 46%. The mortality rate was 15%. In cases of long-term observation, the manifestations of pathological changes started from the nasal cavity, then spreaded in the perimaxillary adipose tissue and orbit, and were followed by the development of intracranial complications.Conclusion. The accumulated experience in identifying the combination of CT and MRI signs and patterns of RCM combined with clinical and anamnestic data allows to increase the alertness of clinicians and radiologists for earlier diagnosis and selection of the optimal volume of surgical intervention.
{"title":"Rhinocerebral Mucormycosis in Patients with Diabetes Mellitus After a New Coronavirus Infection (COVID-19): СT and MRI Patterns Data","authors":"I. S. Gabdulganieva, N. R. Munirova, A. R. Zaripova, V. Anisimov","doi":"10.20862/0042-4676-2022-103-4-6-36-51","DOIUrl":"https://doi.org/10.20862/0042-4676-2022-103-4-6-36-51","url":null,"abstract":"Objective: to study the computed tomography (CT) and magnetic resonance imaging (MRI) manifestations of rhinocerebral mucormycosis (RCM) in patients with diabetes mellitus and new coronavirus infection, to develop attentive attitude of radiologists for early detection of this pathology, rapid surgery and followup examinations.Material and methods. Totally 53 head (facial skull, soft facial tissues and brain) CT and MRI studies were performed in 13 patients with RCM. The number of CT and MRI studies varied from 1 to 9 per one patient, depending on the severity of his condition and clinical indications; the follow-up period was 1–4 months. All patients received surgical aid; diagnosis was verified by microscopy of surgical samples of excised necrotic tissues. A detailed descriptive analysis of pathological changes on CT and MRI characterizing RCM was carried out. The sequence of pathological signs manifestations was described, the prevalence of the lesion was estimated for planning the scope of surgical intervention. A comparative analysis of the identified RCM signs with the literature data was performed.Results. Lesions of the nasal cavity and paranasal sinuses in RCM were found in 100% of our observations, with approximately equal single and bilateral lesions of 54% and 46%, respectively. Lesions of the perimaxillar fatty tissue and pterygoid fossa were determined in 77% of patients, unilateral orbital lesions – in 23%, superior orbital vein and cavernous sinus thrombosis – in 31%, facial soft tissue lesion – in 15.5%, intracranial spread through the perineural spaces – in 7.7%, internal carotid artery arteritis – in 15.5%. Brain substance and meninges involvement in the pathological process was observed in the form of cerebritis in 23% of patients and meningitis in 46%. The formation of brain abscess was noted in follow up examinations in 15.5% of patients, skull bones osteomyelitis was diagnosed in 46%. The mortality rate was 15%. In cases of long-term observation, the manifestations of pathological changes started from the nasal cavity, then spreaded in the perimaxillary adipose tissue and orbit, and were followed by the development of intracranial complications.Conclusion. The accumulated experience in identifying the combination of CT and MRI signs and patterns of RCM combined with clinical and anamnestic data allows to increase the alertness of clinicians and radiologists for earlier diagnosis and selection of the optimal volume of surgical intervention.","PeriodicalId":34090,"journal":{"name":"Vestnik rentgenologii i radiologii","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45051628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-26DOI: 10.20862/0042-4676-2022-103-4-6-18-27
K. S. Drzhevetskaya, G. P. Korzhenkova
Objective: approbation of the project of mass breast cancer mammographic screening in the Kaluga Region.Material and methods. From April 2018 to December 2019, screening mammography was performed in 35,439 women aged from 38 to 93 years (mean age 57.33 ± 8.07 years). The study was carried out on mobile mammography complexes assembled on Russian KamAZ vehicles with Russian-made equipment from Amiko company. Mammography was performed in frontal and oblique projections. BI-RADS ACR international classification was used to standardize the identified changes and assess the sensitivity and specificity of the study method.Results. Out of the total number of women examined, pathological changes (BI-RADS IV–V) were assumed according to mammography data in 778 (2.2%) cases, of which 700 (1.98%) patients appealed to an oncological institution. Benign processes were found in 394 (1.11%) patients, breast cancer in 164 (0.46%). Without verification of the diagnosis, 137 (0.39%) patients remained under the supervision of oncologists. Distribution of detected tumors by stages for 2 years of observation: stage 0 – 7, stage 1 – 73, stage 2 – 56, stage 3 – 13, stage 4 – 3. The stage was not set in 4 cases. The total number of those examined with verification of the diagnosis in the oncological institution was 596. The proportion of correct diagnoses was 94%. The total number of diagnostic errors that would occur in the absence of a true double scan accounted for 36 (6%) cases.Conclusion. The proposed screening method makes it possible to increase the breast cancer detection in the early preclinical stages of the disease, to provide the available diagnostics for the population due to mobile mammography complexes, and to speed up the process of diagnostics and further hospitalization for examination and necessary treatment according to the disease stage in a specialized oncological institution.
{"title":"Results of Two-Years Mammographic Screening in the Kaluga Region","authors":"K. S. Drzhevetskaya, G. P. Korzhenkova","doi":"10.20862/0042-4676-2022-103-4-6-18-27","DOIUrl":"https://doi.org/10.20862/0042-4676-2022-103-4-6-18-27","url":null,"abstract":"Objective: approbation of the project of mass breast cancer mammographic screening in the Kaluga Region.Material and methods. From April 2018 to December 2019, screening mammography was performed in 35,439 women aged from 38 to 93 years (mean age 57.33 ± 8.07 years). The study was carried out on mobile mammography complexes assembled on Russian KamAZ vehicles with Russian-made equipment from Amiko company. Mammography was performed in frontal and oblique projections. BI-RADS ACR international classification was used to standardize the identified changes and assess the sensitivity and specificity of the study method.Results. Out of the total number of women examined, pathological changes (BI-RADS IV–V) were assumed according to mammography data in 778 (2.2%) cases, of which 700 (1.98%) patients appealed to an oncological institution. Benign processes were found in 394 (1.11%) patients, breast cancer in 164 (0.46%). Without verification of the diagnosis, 137 (0.39%) patients remained under the supervision of oncologists. Distribution of detected tumors by stages for 2 years of observation: stage 0 – 7, stage 1 – 73, stage 2 – 56, stage 3 – 13, stage 4 – 3. The stage was not set in 4 cases. The total number of those examined with verification of the diagnosis in the oncological institution was 596. The proportion of correct diagnoses was 94%. The total number of diagnostic errors that would occur in the absence of a true double scan accounted for 36 (6%) cases.Conclusion. The proposed screening method makes it possible to increase the breast cancer detection in the early preclinical stages of the disease, to provide the available diagnostics for the population due to mobile mammography complexes, and to speed up the process of diagnostics and further hospitalization for examination and necessary treatment according to the disease stage in a specialized oncological institution.","PeriodicalId":34090,"journal":{"name":"Vestnik rentgenologii i radiologii","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43405321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-26DOI: 10.20862/0042-4676-2022-103-4-6-71-77
А. Nikogosova, А. B. Berdalin, I. Gubskiy, V. Lelyuk
Objective: to analyze the X-ray liver attenuation values in hospitalized patients with novel coronavirus infection (COVID-19) in relation to the time of disease onset, the severity of pulmonary parenchymal involvement, and the disease outcome.Material and methods. Chest computed tomography (CT) findings in 635 patients hospitalized with COVID-19 were analyzed. CT was performed at various times after the disease onset. The attenuation (CT density) values of the visualized liver upper part were measured by selecting the region of interest on CT images. The extent of the affected lung parenchyma was assessed according to the five-step CT0–4 scale, where CT0 corresponds to the absence of viral pneumonia, CT1 – lung parenchyma involvement less than 25%, CT2 – 25–50% lung volume lesion, CT3 – 50–75% lung volume lesion, CT4 – lung parenchyma involvement more than 75%.Results. In patients with CT0, the liver attenuation was significantly higher than in those with CT1, CT2, CT3, and CT4 (p < 0.01). During the first week of the disease, there was a decrease in liver CT density followed by its increase and return to the initial values (p < 0.0005). The dynamics of liver attenuation in the group of patients who died did not differ significantly from those who survived and recovered (p = 0.107). In the early stage of the disease (0–4 days), the liver attenuation in the group of patients who subsequently died turned out to be significantly lower than in the survivors (p < 0.05).Conclusion. The course of COVID-19 is characterized by a transient decrease in liver CT density. The reduction in liver attenuation does not correlate with the volume of the affected lung parenchyma in patients with CT2–4. The dynamics of liver CT density is not associated with the disease outcome. There is a trend towards more pronounced values of liver attenuation decrease in the early stage of the disease in patients who subsequently died, which requires further research.
{"title":"Liver X-ray Attenuation in Patients with Novel Coronavirus Infection (Multislice Computed Tomography Study)","authors":"А. Nikogosova, А. B. Berdalin, I. Gubskiy, V. Lelyuk","doi":"10.20862/0042-4676-2022-103-4-6-71-77","DOIUrl":"https://doi.org/10.20862/0042-4676-2022-103-4-6-71-77","url":null,"abstract":"Objective: to analyze the X-ray liver attenuation values in hospitalized patients with novel coronavirus infection (COVID-19) in relation to the time of disease onset, the severity of pulmonary parenchymal involvement, and the disease outcome.Material and methods. Chest computed tomography (CT) findings in 635 patients hospitalized with COVID-19 were analyzed. CT was performed at various times after the disease onset. The attenuation (CT density) values of the visualized liver upper part were measured by selecting the region of interest on CT images. The extent of the affected lung parenchyma was assessed according to the five-step CT0–4 scale, where CT0 corresponds to the absence of viral pneumonia, CT1 – lung parenchyma involvement less than 25%, CT2 – 25–50% lung volume lesion, CT3 – 50–75% lung volume lesion, CT4 – lung parenchyma involvement more than 75%.Results. In patients with CT0, the liver attenuation was significantly higher than in those with CT1, CT2, CT3, and CT4 (p < 0.01). During the first week of the disease, there was a decrease in liver CT density followed by its increase and return to the initial values (p < 0.0005). The dynamics of liver attenuation in the group of patients who died did not differ significantly from those who survived and recovered (p = 0.107). In the early stage of the disease (0–4 days), the liver attenuation in the group of patients who subsequently died turned out to be significantly lower than in the survivors (p < 0.05).Conclusion. The course of COVID-19 is characterized by a transient decrease in liver CT density. The reduction in liver attenuation does not correlate with the volume of the affected lung parenchyma in patients with CT2–4. The dynamics of liver CT density is not associated with the disease outcome. There is a trend towards more pronounced values of liver attenuation decrease in the early stage of the disease in patients who subsequently died, which requires further research.","PeriodicalId":34090,"journal":{"name":"Vestnik rentgenologii i radiologii","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43461558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}