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Effect of Sharbat-i-Anar Sheerin (pomegranate juice) in nausea and vomiting in pregnancy: A pre- and post-interventional study 石榴汁对妊娠期恶心呕吐的影响:干预前和干预后的研究
Pub Date : 2023-01-01 DOI: 10.4103/hmj.hmj_10_23
Ismath Shameem, None Meharunnisa, Vandana Rajak, Siddiqui Sumaiya, K Radhika
Background: Qay’al-hamal (Nausea and vomiting in pregnancy) is the most common gastrointestinal symptom of pregnancy, occurring in 80-85% of all pregnancies during the first trimester. The severity of nausea and vomiting in pregnancy (NVP) affects both the mother and foetus. Aims and Objectives: The objective planned for the study was to evaluate the effect of Sharbat-i-Anar Sheerin (Pomegranate Juice) in NVP. Materials and Methods: An open observational study was carried out in the Dept. of Ilmul Qabalat wa Amraze Niswan, National Institute of Unani Medicine Hospital, Bengaluru. Pregnant women 18-35 years of age, having singleton pregnancy in 6-12 weeks of gestational age with NVP (n=30) were included based on mild to moderate Pregnancy Unique Quantification of Emesis (PUQE-24) score and patients with severe NVP, systemic diseases, multiple gestation, ectopic and molar pregnancy were excluded. Sharbat-i-Anar Sheerin (20 ml) twice daily was administered orally on empty stomach for four weeks. The main outcome measure was a reduction in PUQE score. Results: 96.7% of pregnant women achieved a reduction in PUQE score and only 3.3% had no reduction. Mean±SD of PUQE score before, during treatment (on 1st and 2nd follow up), and after treatment (on 1st and 2nd follow up) was 7.73±1.66, 6.03±1.83, 4.97±1.75, 4.13±1.25, 3.7±0.95 respectively (P <0.001). Conclusion: This trial provides evidence of improved effectiveness and safety of Sharbat-i-Anar Sheerin in women with NVP. Moreover, no adverse effect of the research drug was noted during the trial.
背景:妊娠期恶心和呕吐(Qay 'al-hamal)是妊娠期最常见的胃肠道症状,发生在妊娠早期80-85%的妊娠。妊娠期恶心和呕吐(NVP)的严重程度影响母亲和胎儿。目的和目的:本研究的目的是评价石榴汁对NVP的影响。材料和方法:在班加罗尔国立Unani医学医院Ilmul Qabalat wa Amraze Niswan部门进行了一项开放的观察性研究。根据轻至中度妊娠呕吐独特量化(PUQE-24)评分纳入年龄为18-35岁、孕龄6-12周单胎妊娠且NVP的孕妇(n=30),排除重度NVP、全身性疾病、多胎妊娠、异位妊娠和磨牙妊娠患者。空腹口服Sharbat-i-Anar Sheerin (20 ml),每日2次,连续4周。主要结局指标为PUQE评分降低。结果:96.7%的孕妇PUQE评分降低,仅有3.3%的孕妇PUQE评分未降低。治疗前、治疗中(第1、2次随访)、治疗后(第1、2次随访)PUQE评分的均值±SD分别为7.73±1.66、6.03±1.83、4.97±1.75、4.13±1.25、3.7±0.95 (P <0.001)。结论:该试验提供了sharbati - anar Sheerin治疗NVP妇女的有效性和安全性的证据。此外,在试验期间未发现研究药物的不良反应。
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引用次数: 0
Intensive 360° (Capsule) versus conventional phototherapy in neonatal jaundice 强化360°(胶囊)与常规光疗治疗新生儿黄疸的比较
Pub Date : 2023-01-01 DOI: 10.4103/hmj.hmj_59_23
AmmarMohammed Haidar Shehadeh, AamerKamel Sammak, Rikaz Bizzari
Background: Neonatal jaundice is a common condition affecting a high percentage of neonates. In severe cases, if left untreated, it could lead to damaging neurologic complications. Capsule phototherapy is an innovative model of phototherapy that could be faster and more effective than conventional phototherapy. However, to date, only a few studies have compared its effect with conventional phototherapy. Methods: This article is a retrospective, non-randomised and observational study conducted in the neonatal unit at Hatta Hospital, Dubai. All infants above 35-week gestation who presented with neonatal jaundice above the threshold for intensive phototherapy were included in the study. Babies were exposed to conventional intensive phototherapy if the bilirubin level crossed the intensive phototherapy level and to capsule phototherapy once the bilirubin level reached 2.5 mg/dL below the exchange transfusion level. The rate of bilirubin decline and the time needed to reach below the intensive phototherapy level was compared between babies under either model of phototherapy. Results: The efficacy difference was significant, as the mean serum bilirubin decreased 1.29 ± 0.45 mg/dL/h and 0.31 ± 0.13 mg/dL/h in capsule and intensive phototherapy, respectively. The difference was about 0.98 ± 0.23 mg/dL/h, with a P = 0.0001. The duration of treatment in capsule phototherapy was much shorter at 6.45 ± 2.3 h in comparison to 22 ± 10.8 h in intensive phototherapy (difference of 15.5 ± 6.8 h, P = 0.0001). Conclusion: Capsule phototherapy resulted in a faster decline of serum bilirubin level, and therefore, a shorter treatment duration than intensive phototherapy. However, more robust clinical trials with a higher number of subjects are required before suggesting capsule phototherapy, as the standard treatment for severe neonatal jaundice.
背景:新生儿黄疸是影响高比例新生儿的常见疾病。在严重的情况下,如果不及时治疗,可能会导致破坏性的神经系统并发症。胶囊光疗是一种创新的光疗模式,比传统的光疗更快、更有效。然而,迄今为止,只有少数研究将其与传统光疗的效果进行了比较。方法:本文是一项回顾性、非随机、观察性研究,在迪拜哈塔医院新生儿病房进行。所有妊娠35周以上的新生儿黄疸高于强化光治疗阈值的婴儿都被纳入研究。如果婴儿胆红素水平超过强化光疗水平,则接受常规强化光疗,一旦胆红素水平低于交换输血水平2.5 mg/dL,则接受胶囊光疗。比较两种光疗模式下的婴儿胆红素下降率和达到低于强化光疗水平所需的时间。结果:两组疗效差异显著,胶囊组和强化光疗组血清平均胆红素分别降低1.29±0.45 mg/dL/h和0.31±0.13 mg/dL/h。差异约为0.98±0.23 mg/dL/h, P = 0.0001。胶囊光疗的治疗时间为6.45±2.3 h,明显短于强化光疗的22±10.8 h(差异为15.5±6.8 h, P = 0.0001)。结论:胶囊光疗可使血清胆红素水平下降更快,治疗时间比强化光疗短。然而,在建议将胶囊光疗作为新生儿严重黄疸的标准治疗方法之前,需要更多受试者参与的更强有力的临床试验。
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引用次数: 0
N-Terminal pro-B-Type natriuretic peptide correlates with prevalence of microvascular complications in emirati adults with type 2 diabetes mellitus 阿联酋成人2型糖尿病患者中n端前b型利钠肽与微血管并发症发生率相关
Pub Date : 2023-01-01 DOI: 10.4103/hmj.hmj_91_22
PierreSamir Raoof, Alaaeldin Bashier, Marwan Zidan
Background: Pro-B-type natriuretic peptide (BNP) is a well-known predictor of congestive heart failure. No published data, to our knowledge, are available on the correlation of NT-proBNP with microvascular complications of type 2 diabetes in the Emirati population. Aims and Objectives: We aimed to evaluate the correlation between N-terminal-proBNP (NT-proBNP) and microvascular complications in patients with type 2 diabetes and to evaluate the correlation between NT-proBNP and metabolic parameters in patients with type 2 diabetes. Materials and Methods: This was a cross-sectional study conducted from 1st January 2016 to 31st December 2016. Eligible participants with type 2 diabetes were assessed for the evidence of nephropathy, neuropathy and retinopathy as well as biochemical testing for metabolic parameters. They were divided into two groups based on NT-proBNP level (100 pg/mL). Results: The total number of patients recruited was 236; 39.5% (n = 93) had an NT-proBNP of ≥100 pg/mL (Group A), and 60.5% (n = 143) had an NT-proBNP of <100 pg/mL (Group B). The odds ratio (OR) for patients with NT-proBNP ≥100 (Group A) to develop retinopathy was 2.196 (95% confidence interval [CI] 1.307–3.689, P = 0.003), the OR for Group A to develop neuropathy was 1.607 (95% CI 1.046–2.469, P = 0.031), while the OR for Group A to develop microalbuminuria was 1.082 (95% CI 0.855–1.369, P = 0.515). Conclusion: NT-proBNP is related to the prevalence of microvascular complications in patients with type 2 diabetes mellitus. Using NT-proBNP as a marker can define the population of patients at risk who may benefit from the therapeutic interventions to delay microvascular complication.
背景:前b型利钠肽(BNP)是众所周知的充血性心力衰竭的预测因子。据我们所知,在阿联酋人群中,NT-proBNP与2型糖尿病微血管并发症的相关性尚无已发表的数据。目的和目的:我们旨在评估n端probnp (NT-proBNP)与2型糖尿病患者微血管并发症的相关性,并评估NT-proBNP与2型糖尿病患者代谢参数的相关性。材料和方法:这是一项横断面研究,于2016年1月1日至2016年12月31日进行。对符合条件的2型糖尿病患者进行肾病、神经病变和视网膜病变的证据评估,以及代谢参数的生化测试。根据NT-proBNP水平(100 pg/mL)分为两组。结果:共招募患者236例;39.5% (n = 93)的中位数水平以上病人≥100 pg / mL (A组)和60.5% (n = 143)的中位数水平以上病人< 100 pg / mL (B组),比值比(或)患者中位数水平以上病人≥100 (A组)开发视网膜病变是2.196(95%可信区间(CI) 1.307 - -3.689, P = 0.003), A组开发的或神经病变是1.607 (95% CI 1.046 - -2.469, P = 0.031),而A组开发微蛋白尿或为1.082 (95% CI 0.855 - -1.369, P = 0.515)。结论:NT-proBNP与2型糖尿病患者微血管并发症的发生率有关。使用NT-proBNP作为一种标记物,可以确定可能从治疗干预中获益的高危患者群体,以延缓微血管并发症。
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引用次数: 0
A cross-sectional survey on knowledge, beliefs and attitude towards childhood COVID-19 vaccination amongst the parents attending a tertiary care hospital in Kolkata for child health services 在加尔各答一家三级保健医院接受儿童保健服务的父母对儿童COVID-19疫苗接种的知识、信念和态度的横断面调查
Pub Date : 2023-01-01 DOI: 10.4103/hmj.hmj_86_22
M. Datta, Abhishek Reja, Pushpak Das
Background: Before starting the coronavirus vaccination drive in children, it is necessary to know about the knowledge, attitude and perceptions of the parents regarding vaccinating their children. This study aimed to explore the knowledge of the parents of children aged <12 years on coronavirus infection and vaccine and to assess their beliefs and attitude about COVID vaccination amongst the 0–11 years of age group. It also aimed to find out the factors to prefer government facility for COVID vaccination. Materials and Methods: An observational, descriptive, hospital-based cross-sectional study was conducted by interviewing parents who attended Medical College, Kolkata, during November–December, 2021. The data were analysed with the Statistical Package for Social Sciences (SPSS). Results: A total of 106 respondents were interviewed (50.9% males and 49.1% females). All the respondents heard about coronavirus disease and vaccines, almost everybody knew how to prevent transmission of the virus. 56.6% respondents were aware of the correct age group for vaccination and 77.4% considered the vaccines to be safe. Regarding the factors amongst parents to prefer government facilities, significant associations were found with the level of education, employment status, number of children and vaccination status of the parents. Statistical significance level was at P< 0.05. Conclusion: Majority of parents considered existing vaccines as safe for children and almost everyone thought of vaccination as social responsibility. Most parents wanted the vaccines to be given from immunisation clinics or through schools. They also had a clear preference for government facilities.
背景:在开始为儿童接种冠状病毒疫苗之前,有必要了解父母对为孩子接种疫苗的知识、态度和看法。本研究旨在探索<12岁儿童的父母对冠状病毒感染和疫苗的了解,并评估他们对0-11岁年龄组新冠疫苗接种的信念和态度。它还旨在找出更喜欢政府设施接种新冠疫苗的因素。材料和方法:通过采访2021年11月至12月在加尔各答医学院就读的家长,进行了一项观察性、描述性、基于医院的横断面研究。数据采用社会科学统计软件包(SPSS)进行分析。结果:共有106名受访者接受了采访(50.9%为男性,49.1%为女性)。所有受访者都听说过冠状病毒疾病和疫苗,几乎每个人都知道如何防止病毒传播。56.6%的受访者知道接种疫苗的正确年龄组,77.4%的受访者认为疫苗是安全的。关于父母更喜欢政府设施的因素,发现与父母的教育水平、就业状况、子女数量和疫苗接种状况有显著关联。统计学显著性水平为P<0.05。结论:大多数家长认为现有疫苗对儿童安全,几乎每个人都认为接种疫苗是一种社会责任。大多数家长希望通过免疫诊所或学校接种疫苗。他们对政府设施也有明显的偏好。
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引用次数: 0
A prognostic hypoxia gene signature is associated with a dampened tumour immune microenvironment in cervical cancer 预后缺氧基因标记与宫颈癌肿瘤免疫微环境受损有关
Pub Date : 2023-01-01 DOI: 10.4103/hmj.hmj_60_22
R. Khouzam, G. Venkatesh, S. Rao, S. Chouaib
Background: Hypoxia, or low oxygen, is a condition that is characteristic of solid tumours, including cervical cancer. Hypoxia is associated with worse survival in this disease and supports tumorigenic characteristics of stemness, survival, metastasis and angiogenesis, as well as immune resistance. Aims: In this work, we aimed to determine the prognostic significance of a previously derived in vitro eight-gene hypoxia signature in cervical cancer, and to investigate the interplay between the hypoxic and immune features of the cervical tumour microenvironment (TME). Subjects and Methods: The 240 patients with cervical squamous cell carcinoma obtained from the Cancer Genome Atlas Pan-Cancer study were first given a hypoxia score and an immune score (IS) and subsequently subjected to survival analysis. CIBERSORTx was also applied to determine the fractions of immune cells residing in the hypoxia high versus hypoxia low patient groups. Results: We show that the eight-gene hypoxia signature is predictive of worse prognosis in patients with cervical cancer and is associated with a less immunogenic TME. Furthermore, by combining the hypoxia score with an IS to stratify patients based on both their hypoxic and immune status, we achieve an enhancement in survival prediction, with the hypoxia high/immune low subgroup of patients showing the worse probability of overall and disease-specific survival. Conclusions: It is clear from this work that the interplay between the hypoxic and immune microenvironment can contribute to cervical cancer patients' survival. Furthermore, patients with tumours that are both highly hypoxic and immune deprived should be considered for hypoxia-targeted therapy when planning treatment modalities to improve survival.
背景:低氧或低氧是一种实体瘤的特征,包括宫颈癌症。缺氧与这种疾病的生存率较差有关,并支持干性、生存率、转移和血管生成的肿瘤发生特征以及免疫抵抗。目的:在这项工作中,我们旨在确定先前获得的体外八基因缺氧信号在宫颈癌症中的预后意义,并研究宫颈肿瘤微环境(TME)的缺氧和免疫特征之间的相互作用。受试者和方法:从癌症基因组图谱泛癌研究中获得的240例宫颈鳞状细胞癌患者首先进行缺氧评分和免疫评分(IS),随后进行生存分析。CIBERSORTx还用于确定缺氧高与缺氧低患者组中的免疫细胞的组分。结果:我们发现八基因缺氧信号可预测癌症患者的预后恶化,并与免疫原性较低的TME相关。此外,通过将缺氧评分与IS相结合,根据患者的缺氧和免疫状态对其进行分层,我们提高了生存预测,缺氧高/免疫低亚组患者的总体和疾病特异性生存概率较差。结论:从这项工作中可以清楚地看出,缺氧和免疫微环境之间的相互作用有助于宫颈癌症患者的生存。此外,在规划治疗模式以提高生存率时,应考虑对高度缺氧和免疫剥夺的肿瘤患者进行缺氧靶向治疗。
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引用次数: 0
Perspectives of doctors and nurses about the implementation of respectful maternity care in a teaching hospital in India 医生和护士对印度一家教学医院实施尊重产妇护理的看法
Pub Date : 2023-01-01 DOI: 10.4103/hmj.hmj_72_22
Indrani Das, M. Datta, S. Samanta
Background: An important component of the mother-and-baby-friendly birthing facility is respectful maternity care (RMC) during delivery. Aims and Objectives: The objectives of this study were to identify resident doctors' and staff nurses' opinions on the provision of RMC at their workplace, to explore the association between opinion on RMC and respondent's characteristics, and to explore the perceived barriers. Materials and Methods: A facility-based observational, descriptive study of the cross-sectional design was thus conducted among 78 resident doctors and staff nurses posted in the labour room of the study hospital. Data were collected by a predesigned, self-administered questionnaire. Variables included were demographic, service related and opinion on prevalent RMC practice at the respondents' workplace. SPSS version 17 was used for data analysis. Results: Providers' mean age was 30.5 years, and the mean work experience of 3.1 years. About two-thirds of the respondents were resident doctors and 83.3% were female. More than 60% of providers were trained on RMC. Providers reported desirable practices on most items related to RMC except in providers introducing themselves to women, allowing birthing companions and allowing women to assume the position of choice. Opinion about RMC was significantly associated with training status. Uncooperative women were considered the most important barrier to providing optimum RMC. Conclusion: It can be concluded from this study that training providers can reinforce good practices related to RMC and improve the quality of care at birth.
背景:母婴友好分娩设施的一个重要组成部分是分娩期间的尊重产妇护理(RMC)。目的和目的:本研究的目的是确定住院医生和护士对在工作场所提供RMC的意见,探索RMC意见与受访者特征之间的联系,并探索感知障碍。材料和方法:因此,在研究医院产房的78名住院医生和护士中,对横断面设计进行了一项基于设施的观察性描述性研究。数据是通过预先设计的自我管理问卷收集的。变量包括人口统计、服务相关以及对受访者工作场所普遍RMC实践的看法。数据分析采用SPSS 17版软件。结果:提供者的平均年龄为30.5岁,平均工作经验为3.1年。大约三分之二的受访者是住院医生,83.3%是女性。超过60%的供应商接受过RMC培训。提供者报告了与RMC相关的大多数项目的可取做法,除了提供者向女性介绍自己、允许生育伴侣和允许女性担任选择的职位。关于RMC的意见与训练状态显著相关。不合作的妇女被认为是提供最佳RMC的最重要障碍。结论:从这项研究中可以得出结论,培训提供者可以加强与RMC相关的良好实践,提高出生时的护理质量。
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引用次数: 0
Antibiotic consumption in a tertiary care hospital during the pre-COVID-19 and COVID-19 years: A pharmacy-based, retrospective study 在COVID-19前和COVID-19年,三级保健医院的抗生素使用:一项基于药学的回顾性研究
Pub Date : 2023-01-01 DOI: 10.4103/hmj.hmj_82_23
Sarmila Nath, Tanmoy Gangopadhyay, Shritama Banerjee, Pragnadyuti Mandal, DilipKumar Khatua
{"title":"Antibiotic consumption in a tertiary care hospital during the pre-COVID-19 and COVID-19 years: A pharmacy-based, retrospective study","authors":"Sarmila Nath, Tanmoy Gangopadhyay, Shritama Banerjee, Pragnadyuti Mandal, DilipKumar Khatua","doi":"10.4103/hmj.hmj_82_23","DOIUrl":"https://doi.org/10.4103/hmj.hmj_82_23","url":null,"abstract":"","PeriodicalId":34280,"journal":{"name":"Hamdan Medical Journal","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135311642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A rare presentation of psoas abscess causing necrotising fasciitis and meleney's gangrene extending to the perianal region 罕见的腰肌脓肿,引起坏死性筋膜炎及梅氏坏疽,并延伸至肛周
Pub Date : 2023-01-01 DOI: 10.4103/hmj.hmj_84_23
DoaaMohamad Hassan, AlaaAllam Ibrahim Ismail, HasanEbrahim Badawi, AbanobEshak Wanis, AbdullahiMohammed Haji Sufi, MashhourGhonaim Mohammed, AmirMounir Henry
{"title":"A rare presentation of psoas abscess causing necrotising fasciitis and meleney's gangrene extending to the perianal region","authors":"DoaaMohamad Hassan, AlaaAllam Ibrahim Ismail, HasanEbrahim Badawi, AbanobEshak Wanis, AbdullahiMohammed Haji Sufi, MashhourGhonaim Mohammed, AmirMounir Henry","doi":"10.4103/hmj.hmj_84_23","DOIUrl":"https://doi.org/10.4103/hmj.hmj_84_23","url":null,"abstract":"","PeriodicalId":34280,"journal":{"name":"Hamdan Medical Journal","volume":"78 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135313111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epidemiology of pica amongst pregnant women and its clinical, psychological, basic science, realities and myths in UAE 阿联酋孕妇异食癖的流行病学及其临床、心理、基础科学、现实和神话
Pub Date : 2023-01-01 DOI: 10.4103/hmj.hmj_6_23
Hana Iqbal, Batool Khan, Sabila Siddiqui, Hafez Ahmed
Background: Pica is an eating disorder that affects pregnant women which is manifested by craving for ingestion of non-food items that are unusual in kind or quantity e.g. soil, ice, dirt, hair, chalk. Although there is a rich literature describing this behavior from most parts of the world, there is a dearth of studies reporting this behavior in UAE. Aims and Objectives: This cross-sectional exploration study sought to determine the prevalence of pica, its various patterns of presentation, causes, related misconceptions and its impact on behavior and health of pregnant women and their infants in Dubai, UAE. Materials and Method: A random sample of pregnant women (n = 60) were interviewed using an online questionnaire during 2020. Results: The results showed that 57.9% of interviewed women practiced pica, with pagophagia having the highest prevalence (20.4%) followed by sapophagia (8.2%), amylophagia (2%), geophagia (2%), baking soda (2%), coffee ground (2%), roses (2%), paper (2%) and many other rare forms collectively adding up to 59.4%. Age and level of education were not significantly related to the practice of pica. Interestingly, 32.8% of the interviewed women reported that other family members also practiced many patterns of pica during their pregnancies. Effects, myths or misconceptions of pica are also addressed in the study. Conclusion: Several patterns of pica are highly prevalent among pregnant women in the UAE, with pagophagia and sapophagia being the most commonly encountered forms. More than half of the women showed symptoms of stress and anxiety which highlights the importance of studying the pica as a “stress mediator during pregnancy. Iron deficiency anemia and malnutrition are the biggest contributors to the development of pica following pregnancy. In this study, 25% of the respondents had both anaemia and pica. Majority of women were uncertain of the harmful effects of pica which clearly points at the lack of knowledge and understanding of pica. 17.5% of the respondents considered pica to be important for a healthy pregnancy. Given the results, there is no significant relation between the level of education and the practice of pica as 63.3% were graduates of college and University. Our study concluded that pica in pregnant women is associated with weight gain, anemia and polycythemia among their babies.
背景:异食癖是一种影响孕妇的饮食失调症,表现为渴望摄入种类或数量不寻常的非食物物品,如土壤、冰、泥土、头发、粉笔。尽管世界上大多数地方都有丰富的文献描述这种行为,但在阿联酋却缺乏报道这种行为的研究。目的和目的:本横断面探索性研究旨在确定异食癖的患病率,其各种表现形式,原因,相关误解及其对阿联酋迪拜孕妇及其婴儿行为和健康的影响。材料与方法:在2020年期间,随机抽取60名孕妇进行在线问卷调查。结果:57.9%的受访女性患有异食癖,其中食食癖患病率最高(20.4%),其次是食汤症(8.2%)、淀粉症(2%)、食土症(2%)、小苏打(2%)、咖啡粉(2%)、玫瑰(2%)、纸(2%)等多种罕见食食症,共占59.4%。年龄和受教育程度与异食癖的发生无显著相关。有趣的是,32.8%的受访女性报告说,其他家庭成员在怀孕期间也有多种异食癖。异食癖的影响、神话或误解也在研究中得到解决。结论:异食癖的几种类型在阿联酋孕妇中非常普遍,其中食尿癖和食尿癖是最常见的形式。超过一半的女性表现出压力和焦虑的症状,这凸显了研究异食癖作为孕期“压力媒介”的重要性。缺铁性贫血和营养不良是怀孕后发生异食癖的最大原因。在这项研究中,25%的受访者同时患有贫血和异食癖。大多数妇女不确定异食癖的有害影响,这显然表明缺乏对异食癖的知识和理解。17.5%的受访者认为异食癖对健康怀孕很重要。调查结果显示,受教育程度与异食癖的发生没有显著关系,因为63.3%的患者为大专以上学历。我们的研究得出结论,孕妇的异食癖与婴儿体重增加、贫血和红细胞增多症有关。
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引用次数: 0
Primary Papillary Thyroid Carcinoma Arising in a Branchial Cleft Cyst – Navigating a Hidden Malignancy on Histopathology 原发性乳头状甲状腺癌起源于鳃裂囊肿-组织病理学上的隐性恶性肿瘤
Pub Date : 2023-01-01 DOI: 10.4103/hmj.hmj_26_23
Swati Raj, Monika Singh, Mamta Gupta, Naveen Thapliyal
Rationale: Papillary thyroid carcinoma arising from ectopic thyroid tissue within a branchial cleft cyst is extremely rare. To the best of our knowledge, only 17 cases have been reported as Papillary carcinoma in branchial cyst, being primary or secondary in the archives. Only 7 cases are reported as primary, with only 5 cases having regional lymph node metastasis. Patient Concerns: We present a case report of an Indian male in his 30s, presented with complaints of a progressively enlarging, non-tender swelling in the left cervical region for 1 year. Diagnosis: The Contrast - enhanced computed tomography & Fine needle aspiration performed in an outside laboratory showed findings suggestive of branchial cyst. A clinical diagnosis of “branchial cyst” was formed. Interventions: The Cyst excision was done and sent for histopathological examination(HPE) for confirmation. Outcomes: Microscopic examination revealed papillary carcinoma arising from branchial cleft cyst with three out of seven lymph nodes identified showing metastatic deposits. The remaining four lymph nodes showed marked fibrosis and sinus histiocytosis. Then the patient was subjected for total thyroidectomy, which showed no evidence of malignancy on HPE, followed by I-131 radioactive ablation. Lessons: Primary PTC arising in a branchial cleft cyst is an incidental, extremely rare entity and should be kept in mind while dealing with a lateral cervical cystic lesion. They bear a high risk of regional lymph node metastasis. FNAC and radiological investigations alone cannot warrant the diagnosis. Histopathological examination is the key to unlocking the diagnosis and is considered the “gold standard”. Complete cyst excision and regional lymph node removal, along with precautionary hemi- or total thyroidectomy, are highly suggested to reduce metastasis and increase survival rates.
理由:由鳃裂囊肿内异位甲状腺组织引起的甲状腺乳头状癌极为罕见。据我们所知,文献中仅有17例报告为鳃裂囊肿乳头状癌,为原发性或继发性。仅7例为原发病例,仅有5例发生局部淋巴结转移。患者关注:我们提出一个病例报告,印度男性在他的30岁,提出了一个渐进扩大,非压痛性肿胀在左颈椎区域1年的投诉。诊断:在室外实验室进行的对比增强计算机断层扫描和细针穿刺显示提示鳃裂囊肿。临床诊断为鳃裂囊肿。干预措施:囊肿切除后送组织病理学检查(HPE)确认。结果:显微镜检查显示乳头状癌起源于鳃裂囊肿,7个淋巴结中有3个发现有转移性沉积。其余4个淋巴结有明显的纤维化和窦性组织细胞增生。患者行甲状腺全切除术,HPE未见恶性肿瘤,随后行I-131放射性消融术。结论:鳃裂囊肿引起的原发性PTC是一种偶然的、极其罕见的疾病,在处理宫颈外侧囊性病变时应牢记于心。他们有很高的区域淋巴结转移的风险。单凭FNAC和放射检查不能保证诊断。组织病理学检查是开启诊断的关键,被认为是“金标准”。完全囊肿切除和局部淋巴结切除,以及预防性半甲状腺或全甲状腺切除术,强烈建议减少转移和提高生存率。
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引用次数: 0
期刊
Hamdan Medical Journal
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