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Cardiac Hypertrophy: Neonatal Pregnancy Disorder 心脏肥厚:新生儿妊娠障碍
Pub Date : 2022-08-08 DOI: 10.21608/eajbsz.2022.253273
Roba Abdo Ateef Roba Abdo Ateef, S. Fathy
a family history, of pre-gestational diabetes mellitus (PGDM), preeclampsia, or hypertension are at high risk of carrying a fetus with cardiac hypertrophy. These inborn developmental defects might include various cardiac defects along with fetal cardiomyopathy. Symptoms of the disease vary from minor to major and may include chest pain, as well as dyspnea. It is diagnosed based on medical history, a physical exam and echocardiogram results. Protection and treatment of the unborn fetus with cardiac hypertrophy can be achieved via lifestyle adjustment, obesity avoidance, medications and sometimes procedures. The aim of the current research is to address the etiology, diagnosis, pathogenesis and protection from cardiac hypertrophy as a teratological disorder in embryo.
有妊娠前糖尿病(PGDM)、先兆子痫或高血压家族史的人有患心脏肥厚胎儿的高风险。这些先天发育缺陷可能包括各种心脏缺陷以及胎儿心肌病。该病的症状轻重不一,可能包括胸痛和呼吸困难。它是根据病史、体检和超声心动图结果诊断的。保护和治疗心脏肥厚的未出生胎儿可以通过调整生活方式、避免肥胖、药物治疗和有时手术来实现。本研究的目的是探讨胚胎畸形疾病心脏肥厚的病因、诊断、发病机制和预防措施。
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引用次数: 0
Influence of Honeydew Melon, (Cucumis melo L.) Fruit Fractions on The Diabetic Hypercholesterolemic Rats 蜜瓜(cucummelo L.)的影响水果提取物对糖尿病高胆固醇血症大鼠的影响
Pub Date : 2022-08-04 DOI: 10.21608/eajbsz.2022.251818
M. Aly-Aldin
This study aimed to investigate the effect of replacing corn starch in the standard diet of diabetic hypercholesterolemic rats with 3, 6 and 9% levels of honeydew melon fruit powder, peeled honeydew melon fruit powder and honeydew melon peels powder (melon fractions) on the body weight gain, insulin, organs weight, blood glucose, total cholesterol, LDL, triglyceride, kidney functions, liver functions, catalase enzyme, glutathione S-transferase enzyme and malondialdehyde. Data showed diabetes and hypercholesterolemia caused a significant increase in body weight gain, organs weight, blood glucose, total cholesterol, LDL, triglyceride, kidney functions, liver functions and malondialdehyde as well as a significant decrease in insulin, catalase enzyme and glutathione S-transferase enzyme of rats. The feeding with any level of melon fractions restored the normal liver weight and AST level in diabetic hypercholesterolemic rats to the normal values in negative control rats. Also, feeding with 9% melon fractions restored the normal body weight gain, insulin, kidney weight, heart weight, urea, creatinine, ALT, catalase enzyme, glutathione S-transferase enzyme and malondialdehyde in diabetic hypercholesterolemic rats to the normal values in negative control rats. Although glucose, total cholesterol, LDL, triglyceride, and ALP in diabetic hypercholesterolemic rats were decreased by increasing the melon fraction levels but did not return to normal values in negative control rats.
本研究旨在探讨用3、6、9%水平的蜜瓜果粉、去皮蜜瓜果粉和蜜瓜去皮粉(甜瓜部分)替代糖尿病高胆固醇血症大鼠标准日粮中的玉米淀粉对其体重增加、胰岛素、器官重量、血糖、总胆固醇、低密度脂蛋白、甘油三酯、肾功能、肝功能、过氧化氢酶、谷胱甘肽s -转移酶和丙二醛的影响。数据显示,糖尿病和高胆固醇血症导致大鼠体重增加、脏器重量、血糖、总胆固醇、LDL、甘油三酯、肾功能、肝功能和丙二醛显著增加,胰岛素、过氧化氢酶和谷胱甘肽s -转移酶显著降低。饲喂任意水平的甜瓜提取物均可使糖尿病高胆固醇血症大鼠的正常肝脏重量和AST水平恢复到阴性对照大鼠的正常水平。另外,9%甜瓜分饲能使糖尿病高胆固醇血症大鼠的体重增加、胰岛素、肾重、心重、尿素、肌酐、ALT、过氧化氢酶、谷胱甘肽s -转移酶、丙二醛恢复到阴性对照大鼠的正常水平。葡萄糖、总胆固醇、低密度脂蛋白、甘油三酯和ALP在糖尿病高胆固醇血症大鼠中通过增加甜瓜部分水平而降低,但在阴性对照大鼠中没有恢复到正常值。
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引用次数: 1
Extraction and Identification of Bioactive Compounds from Archachatina marginata (Giant African Land Snail). 非洲巨蜗牛中生物活性物质的提取与鉴定。
Pub Date : 2022-08-03 DOI: 10.21608/eajbsz.2022.251817
O. O., O. A., K. R., Saanu, I., Olusegun-Joseph, S., Apena, O.
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引用次数: 0
Effect of Aging on Testis Structure, GLUT2, MTOR Expression and Testosterone Level in Spermatogenesis of The Rats 衰老对大鼠睾丸结构、GLUT2、MTOR表达及睾丸激素水平的影响
Pub Date : 2022-08-03 DOI: 10.21608/eajbsz.2022.252142
Maiada Moustafa, B. Hassan
Background : Male ageing has been previously associated with declining sperm parameters, disrupted hormone secretion and increased time to pregnancy. Aging is a natural ongoing process characterized by morphological and structural degeneration and like other organs. Glucose is essential for testicular function; the uptake of carbohydrate-derived glucose by cells is mediated by glucose transporters (GLUTs). MTOR is also involved in the maintenance and restructuring of the blood-testis barrier (BTB), a key event in the seminiferous epithelium cycle Aim of the work : In the present study, we aimed to investigate the relationship between aging and the expression of GLUT2 and MTOR in the testis, the quality of the spermatogenesis process as well as the testosterone level. Materials and methods: Eighteen rats were classified into the following experimental age groups, premature, mature and aged the rats were weighed and sacrificed by decapitation under a mild dose of anesthetic ether testicular tissue was existed for histological, histochemical, immunohistochemical and molecular techniques. Results: In the aged group, Hematoxylin and Eosin stain, showed a decreased number of sperms that were observed in the lumen of seminiferous tubules, weak PAS reaction in basement membranes moderate immunohistochemical reaction for GLUT2 and MTOR antibodies, also decreased level of testosterone hormone was observed. Conclusion : spermatogenesis process is affected badly by aging that was clear histologically in testicular tissue and the decreased level of testosterone hormone.
背景:男性衰老以前与精子参数下降、激素分泌中断和怀孕时间延长有关。衰老是一种自然的持续过程,其特征是形态和结构的退化,就像其他器官一样。葡萄糖对睾丸功能至关重要;细胞对糖源性葡萄糖的摄取是由葡萄糖转运蛋白(GLUTs)介导的。MTOR还参与了血睾丸屏障(BTB)的维持和重建,这是精细胞上皮周期的一个关键事件。工作目的:在本研究中,我们旨在研究睾丸中GLUT2和MTOR的表达、精子发生过程的质量以及睾酮水平与衰老的关系。材料与方法:将18只大鼠分为早产、成熟和老年三组,称重后在小剂量麻醉醚下斩首处死,取睾丸组织进行组织学、组织化学、免疫组织化学和分子技术分析。结果:老龄组精小管腔内精子数量减少,基底膜PAS反应弱,GLUT2、MTOR抗体免疫组化反应中等,睾酮水平下降。结论:衰老对精子发生过程有明显影响,组织学上表现为睾丸组织衰老和睾丸激素水平下降。
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引用次数: 0
A comparative Study on Bioaccumulation of BTEX and Oxidative Stress Biomarker Response in Parasitised and Non -Parasitised Parachanna obscura (GUNTHER, 1861) from Lekki Lagoon, Lagos, Nigeria 尼日利亚Lekki Lagoon, Lagos, Lekki Lagoon寄生和未寄生的伞蛾(GUNTHER, 1861) BTEX生物积累和氧化应激生物标志物反应的比较研究
Pub Date : 2022-07-30 DOI: 10.21608/eajbsz.2022.251637
A. Bamidele, Ehinlaiye Efi, O. O., O. C., I. Omoregie
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引用次数: 0
The Role of Electrotaenia malopteruri (Fritsch,1886) (Cestoda: Proteocephalidae) in the Fish host Gut Polycyclic Aromatic Hydrocarbons Accumulation, Lipid Profile and Histopathological Alterations in Lekki Lagoon 马氏电带绦虫(Electrotaenia malopteruri, Fritsch,1886)在Lekki泻湖鱼类宿主肠道多环芳烃积累、脂质分布和组织病理学改变中的作用
Pub Date : 2022-07-28 DOI: 10.21608/eajbsz.2022.251636
A. N., A. B., U. D.;, O. C., S. K.
Background : This study investigates the contamination of Polycyclic Aromatic Hydrocarbon residues in the environmental media, Malapterurus electricus , and the parasite, Electrotaenia malopteruri , in the Epe axis of the Lekki Lagoon. The paper also investigates the role of the intestinal parasite in the host-gut PAH accumulation and the effect on the gut lipid profile, anti-oxidants and histological alterations. Grab samples of surface water, sediment, fish liver, intestines and intestinal parasites were collected and analyzed for PAH residues using gas chromatography. The intestines of infected and non-infested fish and the parasite were analyzed for pathological alterations, lipid profile and antioxidant enzymes. Results : The prevalence of the cestode parasite, Electrotaenia malopteruri was 37.21%, among these infected fishes, 14 (16.28%) were females while 18 (20.93%) were males. Among PAHs congeners with 2-3 and 4-6 aromatic cyclic rings, naphthalene had the highest bio-concentration in the fish organs from the environmental media. The fish intestine bioaccumulated naphthalene 181 times more than the surface water concentrations, and 48 times more than the sediment. Other congeners that bioaccumulated in the fish intestine were fluorine, pyrene, dibenz (a,h)anthracene, dibenzo(a,l)pyrene, and benzo(g,h,i)perylene. The parasite bioaccumulated benz (a)anthracene, chrysene, benzo(a)pyrene, and benzo (g,h, i)perylene 18, 23, 3 and 2 times more than the host intestine respectively. The cholesterone, triglycerides and low-density lipid levels in Electrotaenia malopteruri were higher than that in the intestines of the infected and non-infected individuals. The intestinal anti-oxidants induced in the infected and non-infected individuals and in the parasite,
背景:研究了Lekki泻湖Epe轴环境介质Malapterurus electricus和寄生虫Electrotaenia malopteruri中多环芳烃残留物的污染情况。本文还探讨了肠道寄生虫在宿主肠道多环芳烃积累中的作用及其对肠道脂质谱、抗氧化剂和组织学改变的影响。采集地表水、沉积物、鱼肝、肠道和肠道寄生虫的抓样,用气相色谱法分析多环芳烃残留。对感染鱼和未感染鱼以及寄生虫的肠道进行病理改变、脂质特征和抗氧化酶分析。结果:马氏电带绦虫感染率为37.21%,其中雌性14条(16.28%),雄性18条(20.93%);在具有2-3和4-6个芳香环的多环芳烃同系物中,萘在环境介质鱼类器官中的生物浓度最高。鱼肠中积累的萘是地表水浓度的181倍,是沉积物浓度的48倍。在鱼肠中生物积累的其他同系物有氟、芘、二苯并(a,h)蒽、二苯并(a, 1)芘和苯并(g,h,i)苝。该寄生虫的苯并(a)蒽、甲苯、苯并(a)芘和苯并(g,h, i)苝的累积量分别是宿主肠道的18倍、23倍、3倍和2倍。马氏带绦虫的胆固醇、甘油三酯和低密度脂含量高于感染和未感染个体的肠道。在感染和未感染个体以及寄生虫中诱导的肠道抗氧化剂,
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引用次数: 0
Ectoparasites Associated with Migratory Birds, Eastern Desert, Red Sea, Egypt 与候鸟有关的外寄生虫,东部沙漠,红海,埃及
Pub Date : 2022-07-18 DOI: 10.21608/eajbsz.2022.249312
S. Riad
Chewing lice, ticks, mites, and other ectoparasites can infect migratory birds and transmit to resident birds. Ectoparasites cause allergic reactions, irritation, anorexia, decrease in economic income, and may transmit some pathogens between birds. Our current study examined and detected ectoparasites on migratory birds in the Eastern Desert and Gabel El Zeit area, Red Sea, Egypt. During this study, we examined eighty-two migratory birds to detect ectoparasites between March 2019 and May 2022. In this period, we collect 82 newly dead migratory birds belonging to 7 orders; 36 birds of Ciconiiformes, 35 birds of Accipitriformes, four birds of Coraciiformes, two birds of Falconiformes, two birds of Pterocliformes, two birds of Suliformes, and one bird of Columbiformes were examined for ectoparasites. The collected ectoparasites from the migratory birds were preserved freezing or in 70% ethanol until identified as species in the laboratory examination. A total of twenty-six ectoparasite species were collected, belonging to 16 lice, four ticks, four flies, and two mites on migratory birds. Concluded that more studies should be conducted aimed at studying ectoparasites on all species of soaring birds migrating through Egypt.
咀嚼虱子、蜱虫、螨虫和其他体表寄生虫可以感染候鸟并传播给留鸟。体外寄生虫引起过敏反应、刺激、厌食、经济收入减少,并可能在鸟类之间传播某些病原体。本研究对埃及红海东部沙漠和Gabel El Zeit地区候鸟体外寄生虫进行了检测。在这项研究中,我们在2019年3月至2022年5月期间检查了82只候鸟,以检测体外寄生虫。在此期间,共收集到7目新死亡候鸟82只;共检出镜形目鸟类36只,镜形目鸟类35只,喙形目鸟类4只,隼形目鸟类2只,翼形目鸟类2只,刺形目鸟类2只,锥形目鸟类1只。将采集到的候鸟体外寄生虫用冷冻或70%乙醇保存,直至实验室鉴定为物种。共采集候鸟体表寄生虫26种,其中虱类16种,蜱类4种,蝇类4种,螨类2种。结论:应开展更多的研究,以研究穿越埃及的所有飞禽的体外寄生虫。
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引用次数: 2
Herbaceous Weeds as Potential Host Plants for Tetranychus urticae and Predation Efficacy of Typhlodromips capsicum on Preferred Host Plants 草本杂草作为荨麻叶螨潜在寄主植物及辣椒斑蝽对首选寄主植物的捕食效果
Pub Date : 2022-07-03 DOI: 10.21608/eajbsz.2022.247110
E. Mostafa, Abdel-Wahab M. Ali
Tetranychidae), is one of the most serious polyphagous pests worldwide. During intercropping periods, TSSM transfers to available green plants either economic or weeds. The objective of the current study was to determine the host suitability of alternative host plants. The selected promotive host plant for TSSM growth received the phytoseiid predator Typhlodromips capsicum Mostafa to feed on TSSM based on biological features and reproductive potential for prey and predator. Leaves of cheeseweed, bindweed and mint were promotive for TSSM females' longevity which lasted for 16.9, 16.3 and 16.3 days, respectively. The highest significant deposited eggs per TSSM female was recorded on cheeseweed leaves (43.6 eggs, and 3.57eggs/day) with a sex ratio of 2.6: 1 (72.25 % females). Based on TSSM longevity and fecundity, slender amaranth, groundsel, fleabane, wild oat and Jimson weed were less suitable host plants as sorted in descending order. The longevity, prey consumption and fecundity of T. capsicum females were studied on the most suitable plants for TSSM comprising rocket, parsley, mint, bindweed and cheeseweed as sorted in ascending order. The longevity of T. capsicum females on TSSM preferred plants were closely related and the highest significant prey consumption (total 75 and daily 3.95 prey individuals) reared on cheeseweed leaves accompanied by the greatest number of deposited eggs per female (total 38 eggs, and 2.54 eggs/day). The alternative host plants may play a role as a reservoir plant for phytophagous mites also provide food and habitat required for predators conservation during absence periods of major crops to keep biodiversity and natural balance.
叶螨科(Tetranychidae)是世界上最严重的多食性害虫之一。在间作期间,TSSM转移到可用的绿色经济植物或杂草上。本研究的目的是确定替代寄主植物的寄主适宜性。根据食饵和捕食者的生物学特性和繁殖潜力,选择促进TSSM生长的寄主植物,让植物类捕食者辣椒霉(Typhlodromips capsicum Mostafa)以TSSM为食。芝士草、旋花草和薄荷叶对TSSM雌虫的寿命有促进作用,分别为16.9、16.3和16.3 d。每只TSSM雌虫在芝士草叶片上产卵量最高(43.6个,3.57个/d),雌雄比为2.6:1(雌性占72.25%)。根据TSSM的寿命和繁殖力,细长苋菜、groundsel、fleabane、野生燕麦和Jimson weed的适宜寄主植物由高到低排序。研究了辣椒雌虫的寿命、食用量和繁殖力,从高到低依次为红箭菜、欧芹、薄荷、旋花和奶酪草。辣椒粉虱雌虫在TSSM偏好植物上的寿命密切相关,以芝士草叶为食,其食用量最高(75个,每日3.95个),产卵量最高(38个,2.54个/d)。替代寄主植物可作为植食性螨的储存库植物,并在主要作物缺失期为捕食者保护提供所需的食物和栖息地,以保持生物多样性和自然平衡。
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引用次数: 0
A survey of Carnivora Diversity in Bisha district, Southwestern Saudi Arabia 沙特阿拉伯西南部比沙地区食肉动物多样性调查
Pub Date : 2022-06-30 DOI: 10.21608/eajbsz.2022.275175
A. Alqahtani
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引用次数: 0
Protective Effect of Honey Against Zinc Oxide Nanoparticles' Toxicity in Maternal and Foetal Livers of Rat 蜂蜜对氧化锌纳米颗粒对大鼠母胎肝脏毒性的保护作用
Pub Date : 2022-06-30 DOI: 10.21608/eajbsz.2022.246775
Nehad M. Ibrahim, A. Kandil, Ranina Ali., Ranya Yahya, Yasmin M. Mansour, Maiada Moustafa
(ZnO-NPs) used in many industries such as the food industry as additives and are a group of high crystallinity-nano particles. It is a toxic substance, especially when inhaled due to Zn2+ ion that is probably the main toxic material in vivo. The present work was planned to study the protective effect of honey on pregnant rats' livers which received ZnO-NPs and their fetal livers. The pregnant rats were divided into six groups each was 6:8 pregnant rats. The first group served as a control group and received the distilled water. The 2 nd group was administered 10 ml/kg per day of honey from the 6 th to 15 th day of gestation. The 3 rd and 4 th groups were administrated two doses of ZnONPs (10 and 50 mg/kg/day) respectively from the 6 th to 15 th day of gestation. The 5 th and 6 th groups received 10 ml/kg per day of honey before administration of ZnONPs (10 and 50 mg/kg/day). Animals of all groups received the administrated materials orally then they were sacrificed on the 20 th day of gestation. The obtained results showed an increase in the pathological changes in the liver and an increase in the changes in the liver function with the two doses of ZnONPs as compared to the normal control group. Using natural honey reduces the histopathological changes caused by ZnONPs administration.
(ZnO-NPs)是一组高结晶度的纳米颗粒,在食品工业等许多工业中用作添加剂。它是一种有毒物质,特别是由于Zn2+离子吸入,可能是体内主要的有毒物质。本实验拟研究蜂蜜对注射ZnO-NPs的孕鼠肝脏及胎儿肝脏的保护作用。将怀孕大鼠分为6组,每组6∶8。第一组作为对照组,饮用蒸馏水。第二组在妊娠第6 ~ 15天给予蜂蜜10 ml/kg / d。第3组和第4组在妊娠第6 ~ 15天分别给予ZnONPs 10和50 mg/kg/d。第5组和第6组在给予ZnONPs(10和50 mg/kg/d)之前,先给予蜂蜜10 ml/kg /d。各组动物口服给药后,于妊娠第20天处死。结果显示,与正常对照组相比,两剂量ZnONPs使肝脏病理改变增加,肝功能改变增加。使用天然蜂蜜可以减少由ZnONPs引起的组织病理变化。
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引用次数: 0
期刊
Egyptian Academic Journal of Biological Sciences B Zoology
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