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Cryptorchidism: a comprehensive assessment of the terminology and classification 隐睾症:对术语和分类的综合评估
Pub Date : 2021-07-10 DOI: 10.21886/2308-6424-2021-9-2-7-15
V. Sizonov, A. Makarov, I. M. Kagantsov, M. Kogan
The analysis of literature data (PubMed database, Google Scholar) is presented, devoted to the problematic study of the cryptorchidism's terminology and classification. The literature periodically calls for systematization terms used in describing the position undescended testis. Due to the confusion in terminology, it is difficult to generalize and analyze the data obtained. The same position of the undescended testis is described differently by various authors, which led to the appearance of many authors' cryptorchidism classifications at the beginning of the 21st century. This review of the literature states the fact that, over time, no consensus has been found regarding the classification of undescended testicles. Currently, there is a need to generalize the available data to select the optimal treatment algorithm. If the treatment algorithm for the palpable testicles is well studied, then the choice of a treatment method for the cryptorchidism non-palpable forms remains debated in the surgical community.
通过对文献资料(PubMed数据库,Google Scholar)的分析,对隐睾症的术语和分类进行了有问题的研究。文献定期要求系统化术语用于描述隐睾的位置。由于术语的混淆,很难概括和分析所获得的数据。不同作者对隐睾的相同位置描述不同,导致21世纪初出现了许多作者的隐睾分类。这篇文献的回顾表明,随着时间的推移,没有共识已经发现关于隐睾的分类。目前需要对现有数据进行归纳,选择最优的治疗算法。如果可触及睾丸的治疗算法研究得很好,那么对于隐睾不可触及形式的治疗方法的选择在外科社区仍然存在争议。
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引用次数: 2
Selective serotonin reuptake inhibitors and spermatogenesis 选择性血清素再摄取抑制剂与精子发生
Pub Date : 2021-07-10 DOI: 10.21886/2308-6424-2021-9-2-74-79
M. Korshunov, E. Korshunova, Yu.V. Kastrikin, S. Darenkov
Introduction. According to the WHO data, depression is a common disease among women and men of reproductive age. One line of the correction of depressive disorders is selective serotonin reuptake inhibitors (SSRIs). The ingestions have shown that using SSRIs harms sperm quality. The literature date of evaluation of male fertility after discontinuation of antidepressants is quite limited.Purpose of the study. To evaluate the influence of Fluoxetine intake on semen parameters, sperm DNA fragmentation and hormonal status.Materials and methods. Twenty-five men (mean age - 35.2 ± 4.5 yo) with depression were included in the study. Fluoxetine (20 mg per day) was prescribed to all the patients for 12 wk. Semen parameters, sperm DNA fragmentation, sex hormones levels were measured before-after treatment and 3 mo behind discontinuation.Results. After 12 weeks of the treatment the mean semen volume decreased from 3.1 ± 0.7 to 2.9 ± 0.7 ml (p = 0.638), sperm concentration - from 39.4 ± 18.5 to 34.3 ± 16.8 mln/ml (p = 0.384), sperm motility decreased from 41.7 ± 7.6 to 35.5 ± 7.8% (p < 0.05), the mean percent of normal morphology form - from с 12.7 ± 2.8 to 10.7 ± 2.2% (p < 0.001). Sperm DNA fragmentation increased 16.2 ± 4.9 to 22.2 ± 4.3% (p < 0.001). The mean semen volume, sperm concentration, motility, percentage of normal morphology increased and reverted to the normal levels after 3 mounts of drug discontinuation. Sperm DNA fragmentation index decreased, and it had the values less than before the treatment that positively correlated with the reduction of depression's symptoms. It was not significant dynamics in hormonal parameters before and after the therapy.Conclusion. Using fluoxetine has a reversible negative effect on male fertility. It is important to inform the patients about the temporary side effects of SSRIs in fatherhood planning cases.
介绍。根据世界卫生组织的数据,抑郁症是育龄女性和男性的常见病。治疗抑郁症的一种方法是选择性血清素再摄取抑制剂(SSRIs)。摄入表明,使用SSRIs会损害精子质量。关于停用抗抑郁药后男性生育能力评价的文献资料相当有限。研究目的:目的:评价氟西汀对精液参数、精子DNA片段化及激素状态的影响。材料和方法。25名患有抑郁症的男性(平均年龄- 35.2±4.5岁)被纳入研究。氟西汀(20mg / d)给予所有患者12周。在治疗前后和停药后3个月分别测量精液参数、精子DNA碎片、性激素水平。治疗12周后,平均精液量从3.1±0.7 ml下降到2.9±0.7 ml (p = 0.638),精子浓度从39.4±18.5下降到34.3±1680 mln/ml (p = 0.384),精子活动力从41.7±7.6下降到35.5±7.8% (p < 0.05),正常形态的平均百分比从12.7±2.8下降到10.7±2.2% (p < 0.001)。精子DNA断裂率增加16.2±4.9 ~ 22.2±4.3% (p < 0.001)。停药3次后,平均精液量、精子浓度、活动力、正常形态百分率均恢复到正常水平。精子DNA断裂指数下降,且其值低于治疗前,与抑郁症症状的减轻呈正相关。治疗前后激素参数变化无显著性变化。使用氟西汀对男性生育能力有可逆的负面影响。在计划生育病例中,告知患者ssri类药物的暂时副作用是很重要的。
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引用次数: 0
XVII Congress «Men's health»: an event report 第十七届大会"男子健康":活动报告
Pub Date : 2021-07-10 DOI: 10.21886/2308-6424-2021-9-2-157-163
N. Sorokin, A. Kamalov
The congress report details the structure and content of the 3-day meetings. Keynote speakers provided specific points of view on various topics in their presentations. The variety of scientific meetings made it possible to interest a wide audience of physicians of various specialities. The multidisciplinarity of the congress as the most important feature was realized with the highest potential.
大会报告详细介绍了为期三天的会议的结构和内容。主讲人在演讲中就不同主题提出了具体的观点。各种各样的科学会议使各种专业的医生引起了广泛的兴趣。大会的多学科性作为其最重要的特点,发挥了最大的潜力。
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引用次数: 0
Urogenital tuberculosis in children 0 - 14 years old in the structure of other localizations of tuberculosis 泌尿生殖道结核多发于0 - 14岁儿童结构中的其他部位结核
Pub Date : 2021-07-10 DOI: 10.21886/2308-6424-2021-9-2-34-44
I. V. Drozdetskaya, A. Mordyk, N. I. Porkulevich
Introduction. Extrapulmonary tuberculosis (EPTB) still has many features: there is a different approach to its definition in different countries, there is no screening, diagnosis is extremely difficult and requires financial costs, and bacteriological verification does not exceed 46%, complex restorative and reconstructive operations are used in treatment. the proportion of patients with isolated extrapulmonary localizations among tuberculosis patients is low.Purpose of the study. To study the structure of tuberculosis (TB) in children with the accentuation of EPTB in the current conditions to determine the development areas of preventive and diagnostic measures.Materials and methods. A retrospective two-stage study was carried out in the period from 1989 to 2018 among in-patient children aged 0 - 14 yrs. At the first stage, the structure of clinical forms of TB was assessed in 2306 children. Three comparison groups were formed following ten-year periods. At the second stage, 4 groups were identified according to age: early age, preschool age, primary school age, prepubertal age. The data obtained in the course of the study were statistically processed using the Microsoft Office 2007 (Microsoft Corp., USA) and Biostat 2009 (AnalystSoft Inc., USA) software package. The differences between the groups were determined using the χ2 test, and significant differences were considered when the value of the p < 0.05 criterion.Results. It was found that throughout the entire observation period in the region, the predominant localization of the specific process was respiratory TB. The proportion of isolated extrapulmonary lesions in children decreased from 11.1% in the period from 1999 to 2008 to 3.4% in the period from 2009 to 2018 (p = 0.000). At the same time, the most frequent localization (60.4 - 77.8% of cases) among EPTB remains urinary TB. In the dynamics from 1989 to 2018, the number of cases of the disease with combined forms of tuberculosis increased (from 3.1% to 7.2%; p = 0.000), mainly due to the establishment of several localizations of the lesion. The frequency of bacteriological confirmation of the diagnosis was significantly different at various localizations of the specific process. In children of the compared periods of childhood, the predominant localization of the specific process was isolated respiratory TB. The isolated extrapulmonary process localizations were more common in the age groups 7 - 11 and 12 - 14 yo, where it accounted for 10.8 - 12.4% of TB cases (p = 0.000). The localization of the EPTB also depended on the children's age. So, young children often developed damage to the osteoarticular system, in preschool children - the genitourinary and lymphatic (peripheral lymphadenopathy) systems, in younger schoolchildren and preschoolers - the genitourinary system. The frequency of bacteriological confirmation of the EPTB increased with the age. The combined forms of a specific process were more often observed in the age group of
介绍。肺外结核(EPTB)仍有许多特点:不同国家对其定义的方法不同,没有筛查,诊断极其困难并需要财政费用,细菌学验证不超过46%,治疗中使用复杂的修复和重建手术。孤立性肺外定位在肺结核患者中的比例较低。研究目的:目的:研究目前情况下EPTB加重儿童结核(TB)的结构,确定预防和诊断措施的发展领域。材料和方法。在1989年至2018年期间,对0 - 14岁住院儿童进行了回顾性两阶段研究。在第一阶段,对2306名儿童的结核病临床形态结构进行了评估。每隔十年形成三个比较组。第二阶段按年龄分为4组:幼儿、学龄前、小学、青春期前。研究过程中获得的数据使用Microsoft Office 2007 (Microsoft Corp., USA)和Biostat 2009 (AnalystSoft Inc., USA)软件包进行统计处理。各组间差异采用χ2检验,以p < 0.05为差异有统计学意义。结果发现,在整个观察期,该地区的特定过程的主要定位是呼吸道结核。儿童孤立性肺外病变比例从1999 - 2008年的11.1%下降到2009 - 2018年的3.4% (p = 0.000)。同时,EPTB中最常见的定位仍然是尿路结核(60.4 ~ 77.8%)。在1989年至2018年的动态中,该疾病合并结核病的病例数有所增加(从3.1%增加到7.2%;P = 0.000),主要是由于建立了病变的几个定位。在特定过程的不同部位,细菌学确诊的频率有显著差异。在儿童的比较时期,主要定位的具体过程是孤立的呼吸道结核。孤立性肺外过程定位在7 ~ 11岁和12 ~ 14岁年龄组更为常见,占结核病例的10.8 ~ 12.4% (p = 0.000)。EPTB的定位也与儿童的年龄有关。因此,年幼的儿童通常会对骨关节系统造成损害,学龄前儿童会对泌尿生殖系统和淋巴系统(外周淋巴结病)造成损害,学龄儿童和学龄前儿童会对泌尿生殖系统造成损害。细菌学证实EPTB的频率随年龄增加而增加。某一特定过程的合并形式多见于7 - 11岁年龄组,其余年龄组分别为77.4%、87.1%和95.0%。呼吸道结核及其他器官结核细菌学确诊以7 ~ 11岁年龄组(19.4%)多见,12 ~ 14岁年龄组(12.9%)、4 ~ 6岁年龄组(10.0%)、早期年龄组(9.7%)多见,远高于单纯呼吸道结核确诊。由于重组结核过敏原和CT广泛引入临床实践,儿童EPTB并没有失去其地位。它更常与呼吸道结核合并发现。在EPTB中,泌尿生殖系统结核占多数,这可以与其他器官的损害相比加以证实。提高儿科医生和儿科医生对EPTB发生频率的认识水平,就有可能对其发展的可能性形成警觉性,并在早期阶段及时发现疾病。
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引用次数: 0
Recurrent varicocele 精索静脉曲张复发
Pub Date : 2021-07-10 DOI: 10.21886/2308-6424-2021-9-2-132-141
S. Kotov, N. D. Korochkin, A. Klimenko
Varicocele is one of the most common problems in modern reproductive medicine. The incidence of varicocele in the structure of the general male population is 15%, 40% of which have problems with fertility. Among the causes of male infertility, varicocele ranks second after idiopathic, thus being the most common curable cause of male infertility. While researching the pathophysiological mechanisms of infertility in varicocele, the question of the reasons for the varicocele relapses, both after surgical and endovascular methods of treatment remains open, as well as the tactics of managing such patients. The review aimed to systematize knowledge about the problem of recurrent varicocele, to analyze the frequency and etiology of relapses after various methods of primary treatment, as well as to select the optimal diagnostic and treatment option for varicocele recurrence.
精索静脉曲张是现代生殖医学中最常见的问题之一。精索静脉曲张在一般男性人群中的发病率为15%,其中40%有生育问题。在男性不育的原因中,精索静脉曲张排在特发性之后,是男性不育最常见的可治愈的原因。在研究精索静脉曲张不孕的病理生理机制的同时,精索静脉曲张复发的原因,手术和血管内治疗方法,以及处理此类患者的策略等问题仍未解决。本文旨在系统梳理精索静脉曲张复发问题的认识,分析精索静脉曲张在各种初级治疗方法后复发的频率和病因,为精索静脉曲张复发选择最佳的诊断和治疗方案。
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引用次数: 2
Temporary urethral stent with perineal fixation for posterior urethral stenosis (preliminary results) 会阴固定临时尿道支架治疗后尿道狭窄(初步结果)
Pub Date : 2021-07-10 DOI: 10.21886/2308-6424-2021-9-2-80-85
P. Kyzlasov, A. Mustafaev, D. Ostrovsky, A. Martov
Introduction. Urethroplasty is the “gold standard” treatment of urethral stenosis. However, often in connection with old and senile age, as well as due to the presence of concomitant diseases, it is not possible to carry out urethroplasty due to its certain invasiveness. In such cases, one of the methods of treatment is the installation of a urethral stent. But this method has not found practical application due to the frequent migration of stent and the high frequency of its incrustation. The approach developed by us avoids stent migration.Purpose of the study. To evaluate the immediate results of the placement of a urethral stent with fixation through the perineum.Materials and methods. A total of 18 patients with urethral stenosis aged 68 to 84 years have been operated on since February 2019. Ten patients had stenosis of the urethrocystoneoanastomosis after radical prostatectomy, 6 patients had iatrogenic stenosis of the prostatic urethra, 1 patient had post-radiation stenosis of the bulbo-membranous urethra. All patients in the preoperative and postoperative periods underwent: IPSS-QoL questioning, uroflowmetry, bladder ultrasound with residual urine volume evaluation, urethroscopy, ascending and micturition urethrocystography. The first stage was an internal optical urethrotomy according to the standard technique. Then, a urethral stent was installed in the area of dissected stenosis. The second stage was an incision in the perineum, the urethra was isolated, and under optical control, through the perineum, the stent was fixed to the urethra with non-absorbable suture material. The stent was removed endoscopically after 6 months.Results. The median surgery duration averaged 45 minutes. Patients were discharged 2 to 3 days after surgery. The maximum observation period was 20 months. During the observation period, not a single case of stent migration was recorded. All patients showed a persistent increase in Qmax and no residual urine. Six patients had a stress component of urinary incontinence, 4 patients had total urinary incontinence. According to control urethrocystoscopy 6 months after stent removal, clinically insignificant urethral stenosis was noted in all patients. In all cases, moderate signs of stent encrustation were identified. Dysuric phenomena disturbed 5 patients, who were stopped by rectal suppositories with NSAIDs, as well as taking herbal uroseptics. The data from the IPPS-QoL questionnaires confirm the positive effect of the treatment.Conclusions. Temporary placement of a urethral stent for urethral stenosis is an effective minimally invasive treatment. The technique of fixation through the perineum allows preventing migration in all cases. This approach to treatment significantly improves the quality of life of patients who were contraindicated for urethroplasty for one reason or another. However, the technique requires longer observation and analysis.
介绍。尿道成形术是治疗尿道狭窄的“金标准”。然而,通常与老年和老年有关,以及由于存在伴随疾病,由于其一定的侵入性,不可能进行尿道成形术。在这种情况下,治疗方法之一是安装尿道支架。但由于支架移位频繁,结皮频率高,该方法尚未得到实际应用。我们开发的方法避免了支架的迁移。研究目的:目的:评价经会阴固定尿道支架的即刻效果。材料和方法。2019年2月以来,共收治18例68 ~ 84岁尿道狭窄患者。根治性前列腺切除术后尿道结石吻合口狭窄10例,医源性前列腺尿道狭窄6例,放射后球膜性尿道狭窄1例。所有患者术前、术后均行:IPSS-QoL询问、尿流量测定、膀胱超声伴残尿量评估、尿道镜检查、升尿尿尿道造影术。第一阶段是按照标准技术进行内光学尿道切开术。然后在解剖狭窄区放置尿道支架。第二阶段为会阴切口,隔离尿道,在光学控制下,通过会阴,用不可吸收的缝合材料将支架固定在尿道上。6个月后,内镜下取出支架。平均手术时间为45分钟。术后2 ~ 3天出院。最长观察期为20个月。观察期间未发生一例支架移位。所有患者均表现为Qmax持续升高,无尿残。应激性尿失禁6例,完全性尿失禁4例。支架取出后6个月对照尿道镜检查,所有患者均发现临床上不明显的尿道狭窄。在所有病例中,均发现中度支架结痂迹象。5例患者出现排尿困难现象,经直肠栓剂加非甾体抗炎药停用,同时服用消毒药。IPPS-QoL问卷的数据证实了治疗的积极效果。临时放置尿道支架治疗尿道狭窄是一种有效的微创治疗方法。通过会阴的固定技术可以防止所有病例的移位。这种治疗方法显著提高了因某种原因禁忌行尿道成形术患者的生活质量。然而,这项技术需要更长的观察和分析时间。
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引用次数: 0
The effectiveness of extracorporeal shock wave lithotripsy for lower calyx stones in children 体外冲击波碎石治疗儿童下肾盏结石的疗效观察
Pub Date : 2021-07-09 DOI: 10.21886/2308-6424-2021-9-2-56-63
I. V. Klyuka, V. Sizonov, Olesya A. Shaldenko, Yulia V. Lukash, B. Mikael, Chibichyan, M. I. Kogan
Introduction. According to current clinical guidelines, the use of extracorporeal shock wave lithotripsy (ESWL) for lower calyx stones is indicated when their size is less than 1 cm. This is due to the low efficiency and high frequency of repeated procedures for larger stones.Purpose of the study. To examine the results of ESWL usage in the treatment of children with lower calyx stones of various sizes.Materials and methods. ESWL was performed on 33 children with lower calyx stones during 2013 - 2018 yrs. Patients were divided into 2 groups: Group I - 24 (72.7%) patients with primary stones, Group II - 9 (27.3%) patients after ESWL of kidney pelvis stones that migrated to the lower calyx. Both groups are divided into subgroups: a - children with stones less than 1 cm and b - with stones more than 1 cm. ESWL was performed under general anesthesia and ultrasound guidance. In all patients after ESWL we used the inversion technique. The result was considered positive in case of the complete elimination of stones was achieved.Results. After the first ESWL session, stone-free status was achieved in 21/33 (63.6%) patients of all groups, after the second ESWL session in 26/33 (78.8%), after 3 sessions - 30/33 (90.9%). In subgroups Ia and IIa, there were 14/22 (63.6%) children after the first ESWL with complete elimination of calculi, and after subsequent sessions, the success rate was 90.9% (20/22 calculi). After the first ESWL session in subgroups Ib and IIb, complete elimination of stones was achieved in 7/11 (63.6%) children, after repeated sessions in 10/11 (90.9%) children.Conclusions. ESWL demonstrates a high efficiency in the treatment of lower calyx stones less and more than 1 cm, both after the first and third sessions, and in the treatment of primary and residual (migrated) stones.
介绍。根据目前的临床指南,当下萼结石小于1cm时,应采用体外冲击波碎石(ESWL)治疗。这是由于对较大的宝石进行重复程序的效率低和频率高。研究目的:目的探讨ESWL在治疗不同大小的儿童下萼结石中的应用效果。材料和方法。2013 - 2018年对33例下萼结石患儿进行体外冲击波碎石治疗。患者分为2组:原发性结石患者I - 24例(72.7%),肾盂结石经ESWL移至下肾盏患者II - 9例(27.3%)。两组都分为亚组:a -结石小于1厘米的儿童,b -结石大于1厘米的儿童。超声引导下全身麻醉行体外冲击波碎石。在所有ESWL后的患者中,我们使用了内翻技术。如果完全消除了结石,结果被认为是积极的。第一次ESWL治疗后,21/33例(63.6%)患者无结石,第二次ESWL治疗后26/33例(78.8%)无结石,第3次ESWL治疗后30/33例(90.9%)无结石。在Ia亚组和IIa亚组中,第一次ESWL后结石完全消除的患儿有14/22(63.6%),后续治疗的成功率为90.9%(20/22)。在Ib和IIb亚组的第一次ESWL治疗后,7/11(63.6%)的儿童完全消除了结石,10/11(90.9%)的儿童在重复治疗后完全消除了结石。ESWL在第一次和第三次治疗后,对于小于和大于1厘米的下萼结石,以及原发性和残余(迁移)结石的治疗都显示出高效率。
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引用次数: 1
Percutaneous antegrade ureterolithotripsy for proximal ureteral stones: overview own experience use 经皮输尿管顺行碎石术治疗输尿管近端结石:综述自己的使用经验
Pub Date : 2021-07-09 DOI: 10.21886/2308-6424-2021-9-2-92-99
S. Popov, R. Guseinov, N. Gadjiev, A. V. Davydov, V. Obidnyak, R. S. Barhitdinov, V. V. Perepelitsa
Introduction. Currently, a large number of techniques are used in the treatment of patients with ureteral stones: extracorporeal shock-wave lithotripsy (ESWL), retrograde ureterolithotripsy (RULT), laparoscopic and retro-peritoneoscopic ureterolithotomy.Purpose of the study. To evaluate the possibilities and effectiveness of percutaneous antegrade ureterolithotripsy in the treatment of patients with proximal ureteral stones in comparison with transurethral contact ureterolithotripsy.Materials and methods. Twenty-eight patients with urolithiasis were treated, who underwent percutaneous antegrade ureterolithotripsy (PAULT) and 27 patients of the control group, who underwent RULT. All patients included in the study underwent a standard preoperative examination: complete blood count and urine analysis, bacteriological urine culture, biochemical tests, and X-ray research methods. Plain urography, renal ultrasound, computed tomography were used as imaging methods. The OLYMPUS URF-V3 8.4 Ch (Olympus Europa SE & Co. KG., Germany) video uretero-renoscope was used for PAULT in patients of the main group; lithotripsy was performed using thulium laser. The results of the study were subjected to statistical processing in order to determine the statistical significance of the differences between the data obtained. Quantitative variables were described using the arithmetic mean (M) and standard deviation (5). Qualitative variables were estimated by absolute and relative frequencies (percentages). The data were considered reliable at p values < 0.05.Results. The average time of surgical intervention in patients of the main group from the moment of placement of the ureteral catheter was 47 ± 12 min, with access without preliminary renal catheterization: 28 ± 4 min. Average time of surgical intervention in patients of the control group: 42.0 ± 10.7 minutes. The presented data indicate a significant (p < 0.05) greater cases' number of complete stone removal among patients of the main group compared with patients in the control group (74.0%).Conclusion. PAULT is preferred among choice treatment methods for patients with proximal ureteral large stones, for whom RULT and ESWL cannot be performed with a high level of “stone-free” rate and a minimum number of complications.
介绍。目前,输尿管结石患者的治疗采用了大量的技术:体外冲击波碎石术(ESWL)、逆行输尿管碎石术(RULT)、腹腔镜和后腹膜镜输尿管取石术。研究目的:目的探讨经皮输尿管顺行碎石术与经尿道接触输尿管碎石术治疗输尿管近端结石的可行性和有效性。材料和方法。28例尿石症患者行经皮输尿管顺行碎石术(pult),对照组27例行RULT。所有纳入研究的患者都进行了标准的术前检查:全血细胞计数和尿液分析,细菌学尿液培养,生化检查和x线研究方法。影像学方法包括尿路平片、肾脏超声、计算机断层扫描。OLYMPUS URF-V3 8.4 Ch (OLYMPUS Europa SE & Co. KG)。主组患者采用输尿管镜(德国)视频输尿管镜;采用铥激光碎石。对研究结果进行统计处理,以确定所得数据之间差异的统计显著性。定量变量用算术平均值(M)和标准差(5)来描述。定性变量用绝对频率和相对频率(百分比)来估计。当p值< 0.05时,认为数据可靠。主组患者自输尿管置管时刻起平均手术介入时间为47±12 min,未行前期肾置管时平均手术介入时间为28±4 min。对照组患者平均手术介入时间为42.0±10.7 min。本组资料显示,主组患者结石完全取出例数(74.0%)明显高于对照组(p < 0.05)。输尿管近端大结石患者首选的治疗方法是PAULT,对于输尿管近端大结石患者,RULT和ESWL不能以高的“无石”率和最少的并发症进行治疗。
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引用次数: 0
The significance of coronavirus infection in the development of reproductive and lower urinary tract lesions 冠状病毒感染在生殖和下尿路病变发生中的意义
Pub Date : 2021-07-08 DOI: 10.21886/2308-6424-2021-9-2-125-131
Александра Т. Атаджанова, Khalid S. Ibishev, Aleksandra T. Atadzhanova, Eldar A. Mamedov, Oleg N. Vasilyev
The impact of COVID-19 on the organs of the genitourinary system is of particular interest to the urologist. There is insufficient information about this influence up to date. The studies are actively developing and require long-term data analysis to determine possible long-term complications, persistent changes in physiological parameters and anatomical and histological structures, as well as to establish the possibility of regression of these changes and complications. The results obtained will undoubtedly improve not only the diagnosis, treatment and prevention of coronavirus infection and its complications, but also make it possible to predict certain disease's outcomes and changes in the function of organs and systems. In turn, this will give an understanding of the measures that need to be taken to completely avoid or minimize these complications and changes.This review focuses on the impact of COVID-19 on genitourinary organs, particularly its place in the development of the lower urinary tract and reproductive organs lesions, as well as the role of androgens in the course of SARS-CoV-2.
COVID-19对泌尿生殖系统器官的影响是泌尿科医生特别感兴趣的。到目前为止,关于这种影响的信息还不充分。这些研究正在积极开展,需要长期的数据分析,以确定可能的长期并发症,生理参数和解剖组织学结构的持续变化,并确定这些变化和并发症回归的可能性。所获得的结果无疑不仅将改善冠状病毒感染及其并发症的诊断、治疗和预防,而且还可以预测某些疾病的结局和器官和系统功能的变化。反过来,这将使人们了解为完全避免或尽量减少这些并发症和变化而需要采取的措施。本文综述了COVID-19对泌尿生殖器官的影响,特别是其在下尿路和生殖器官病变发展中的作用,以及雄激素在SARS-CoV-2过程中的作用。
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引用次数: 3
Peyronie's disease and the first user experience of Peyroflex® 佩罗尼氏病和Peyroflex®的首次用户体验
Pub Date : 2021-07-08 DOI: 10.21886/2308-6424-2021-9-2-150-156
G. Shirin, N. Fedorova
The article deals with the current issues of the etiology, pathogenesis and clinical course of Peyronie's disease. The diagnostic possibilities of using ultrasound sonography are demonstrated. The international data on known treatment options for Peyronie's disease are reviewed. The author describes his own user experience of the Peyroflex® at an early stage of the disease and gives a preliminary assessment of its effectiveness.
本文就佩罗尼氏病的病因、发病机制及临床病程等方面的研究进展作一综述。本文论证了超声诊断的可能性。本文回顾了关于佩罗尼氏病已知治疗方案的国际数据。作者描述了他自己在疾病早期阶段使用Peyroflex®的用户体验,并对其有效性进行了初步评估。
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引用次数: 1
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Vestnik Urologii
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