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Loneliness and health: An umbrella review 孤独与健康:综述
Q4 Psychology Pub Date : 2022-10-01 DOI: 10.4103/hm.hm_51_22
N. Rezaei, A. Saghazadeh
Loneliness has been associated with different health outcomes in the following domains: general health, well-being, physical health, mental health, sleep, and cognitive function. However, the most significant associations fall into mental health- and well-being-related outcomes. Moreover, loneliness is an identified risk factor for all-cause mortality. This article overviews the systematic and meta-analytic studies, which have investigated epidemiology and etiology, associated medical and neuropsychiatric conditions, and interventions for loneliness. Meta-analyses have associated higher levels/prevalence of loneliness with pathological conditions, including physical (cardiovascular diseases, obesity, and cancer) and mental health conditions (dementia, cognitive impairment, depression, anxiety, suicide, substance abuse, frailty, and addiction). Furthermore, loneliness commonly occurs to people during particular physiological conditions, for example, childhood, adulthood, elderly, pregnancy, and taking care of others. Moreover, young adults commonly experience transient loneliness. For all these pathological/physiological conditions, COVID-19 has been confirmed as a loneliness-worsening condition. Genetic background, in addition to environmental factors, plays a role in the etiology of loneliness. Biomarkers mainly include neural correlates, including aberrations in the structure/function of cognitive or emotional control-related brain regions, inflammatory correlates, and anthropometric measures. The current interventions for loneliness alleviation are mostly focused on older people, for whom the evidence derived from systematic or meta-analytic studies shows none-to-moderate benefits and substantial heterogeneity across studies. The evidence is not adequate to conclude about the effectiveness of interventions in youth. In addition to the need for pathology- and population-specific interventions for loneliness reduction/prevention, there is a need to survey loneliness longitudinally to examine the causality of loneliness-health associations.
孤独感与以下领域的不同健康结果有关:总体健康、幸福感、身体健康、心理健康、睡眠和认知功能。然而,最重要的关联属于心理健康和幸福相关的结果。此外,孤独是全因死亡率的一个已确定的风险因素。本文综述了系统和荟萃分析研究,这些研究调查了流行病学和病因、相关的医学和神经精神状况以及孤独的干预措施。Meta-analysis将较高水平/患病率的孤独与病理状况相关,包括身体状况(心血管疾病、肥胖和癌症)和心理健康状况(痴呆症、认知障碍、抑郁症、焦虑症、自杀、药物滥用、虚弱和成瘾)。此外,孤独感通常发生在特定的生理条件下,例如童年、成年、老年、怀孕和照顾他人。此外,年轻人通常会经历短暂的孤独。对于所有这些病理/生理状况,新冠肺炎已被证实是一种孤独的恶化状况。除了环境因素外,遗传背景在孤独的病因中也起着一定作用。生物标志物主要包括神经相关性,包括认知或情绪控制相关大脑区域的结构/功能异常、炎症相关性和人体测量。目前缓解孤独感的干预措施主要集中在老年人身上,从系统或荟萃分析研究中获得的证据表明,对他们来说,没有到中等程度的益处,而且研究之间存在很大的异质性。这些证据不足以对干预措施对青年的有效性作出结论。除了需要针对病理学和人群的干预措施来减少/预防孤独感外,还需要纵向调查孤独感,以检验孤独感与健康之间的因果关系。
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引用次数: 0
Necklace pattern left ventricular noncompaction cardiomyopathy with plethora of paradoxic septal premature ventricular complexes: A case report and literature review 项链型左室非压实性心肌病伴悖论性室间隔过早心室复合体过多:1例报告及文献复习
Q4 Psychology Pub Date : 2022-10-01 DOI: 10.4103/hm.hm_69_21
Debasish Das, Abhinav Kumar, A. Banerjee, Tutan Das, S. Singh, Manaranjan Dixit
We report an extremely rare case of left ventricular noncompaction (LVNC) cardiomyopathy sparing the anterior ventricular wall in an interesting “necklace” pattern in parasternal short axis view in a 76-year-old female with frequent palpitation and shortness of breath for the last 6 months. Interestingly, the patient had a plethora of basal septal premature ventricular complexes (PVCs) both from the anterior and posterior aspects of the paradoxically thinned-out basal septum and they were not from the segment of noncompacted (NC) myocardium. Our case is unique and the first to describe the LVNC in an interesting shape of “necklace” sparing the left ventricular anterior, anteroseptal, and anterolateral wall and paradoxically arising plethora of septal PVCs from the thinned-out basal septum deteriorating the left ventricular function rapidly in an elderly female in her seventh decade of life. Although commonly in LVNC, the PVCs arise from the NC segment, in this unique case plethora of PVCs paradoxically arising from the basal septum were contributing toward rapid deterioration of left ventricular systolic function in an elderly patient in her seventh decade of life without the presence of conventional risk factors.
我们报告一例极其罕见的左心室非压实性心肌病(LVNC),在胸骨旁短轴位上以有趣的“项链”模式保留前心室壁,患者为76岁女性,过去6个月频繁心悸和呼吸急促。有趣的是,患者有大量的基底间隔早室性复合体(室性早搏),均来自似是而非变薄的基底间隔前部和后部,而不是来自非紧致(NC)心肌段。我们的病例是独特的,并且是第一个描述LVNC以有趣的“项链”形状保留左心室前壁、前间隔壁和前外侧壁的病例,并且矛盾地从变薄的基底间隔产生过多的室间隔室性早衰,导致一位老年女性在她生命的第七十岁时左心室功能迅速恶化。尽管在LVNC中,室性早搏通常起源于NC段,但在这个独特的病例中,大量的室性早搏矛盾地起源于基底隔,导致了一位70多岁的老年患者左室收缩功能的快速恶化,而没有传统的危险因素。
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引用次数: 0
Is noise exposure a risk factor for cardiovascular diseases? A literature review 噪音暴露是心血管疾病的危险因素吗?文献综述
Q4 Psychology Pub Date : 2022-10-01 DOI: 10.4103/hm.hm_48_22
A. Faria, A. Caldas, I. Laher
We are exposed to noise on a daily basis, and noise pollution is increasingly becoming more intense, especially with more people living in the urban areas. Cardiovascular diseases (CVDs) are the leading cause of mortality worldwide and of global public health concern. Preventing and treating CVDs requires a better understanding of the associated risk factors. There is emerging evidence that noise pollution, especially related to the various forms of transport, is likely a contributor to the pathogenesis and aggravation of CVDs. We review key epidemiological data that address the link between excessive noise exposure and CVDs in humans and present proposed pathophysiological mechanisms underlying this association.
我们每天都暴露在噪音中,噪音污染越来越严重,尤其是随着越来越多的人生活在城市地区。心血管疾病(cvd)是世界范围内死亡的主要原因,也是全球公共卫生关注的问题。预防和治疗心血管疾病需要更好地了解相关风险因素。越来越多的证据表明,噪音污染,特别是与各种形式的运输有关的噪音污染,可能是心血管疾病发病和恶化的一个因素。我们回顾了主要的流行病学数据,这些数据解决了过度噪声暴露与人类心血管疾病之间的联系,并提出了这种联系背后的病理生理机制。
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引用次数: 1
Psychosocial stressors in psychosomatic cardiology: A narrative review 心身心脏病学中的社会心理压力源:叙述性回顾
Q4 Psychology Pub Date : 2022-10-01 DOI: 10.4103/hm.hm_26_22
T. Theorell
The definition of a psychosocial stressor and reactions to it is discussed in relation to individual and environmental factors. The relation of this model to psychophysiological stress reactions and regeneration, as well as its significance for cardiovascular diseases, is described. Three classes of psychosocial stressors (life changes, work conditions, and family conflicts) are then described in relation to cardiovascular illness and risk factors. Particular emphasis is on longitudinal studies of patients. Heart contractility and urinary adrenaline excretion are discussed in detail. Epidemiological data on psychosocial stressors and cardiovascular disease outcomes (mainly myocardial infarction) are also discussed.
心理社会压力源的定义及其反应与个人和环境因素有关。描述了该模型与心理生理应激反应和再生的关系,以及它对心血管疾病的意义。然后描述了三类心理社会压力源(生活变化、工作条件和家庭冲突)与心血管疾病和风险因素的关系。特别强调对患者的纵向研究。详细讨论了心脏收缩力和尿肾上腺素排泄。还讨论了心理社会压力源和心血管疾病结果(主要是心肌梗死)的流行病学数据。
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引用次数: 2
Perceived stress and cardiovascular disease in a community-based population 社区人群的感知压力和心血管疾病
Q4 Psychology Pub Date : 2022-10-01 DOI: 10.4103/hm.hm_55_22
Yasi Zhang, Aijie Zhang, Jianbang Xiang, Yi-qiang Zhan
Background: Perceived stress plays an important role in the pathogenesis of cardiovascular diseases (CVDs). Their associations with CVDs in the Chinese population are less investigated. The present study aims to investigate the associations of perceived stress with well-defined CVDs in a population-based survey in Shenzhen, China. Methods: In the community-based survey, we recruited 2,287 participants aged 18 years and over from 8 communities in Shenzhen, China. Perceived stress was assessed using the modified Chinese version of the Perceived Stress Scale with 14 items and a five-point Likert scale. CVDs including coronary heart disease, heart failure, and atrial fibrillation were ascertained from electronic health records and confirmed by family physicians. Potential confounders included age, sex, educational attainment, occupation, smoking, and alcohol-drinking habits. Multivariable logistic regression models were employed to estimate the magnitude of the associations. Results: Overall, the average perceived stress score was 37.2 (standard error: 7.2 and range: 14–70) among the participants. The prevalence of CVDs was 2.7%. After controlling for age, sex, educational attainment, occupation, smoking, and alcohol-drinking habits, a higher perceived stress score was significantly associated with higher risks of CVDs (odds ratio [OR]: 1.25, 95% confidence interval [CI]: 1.01–1.55). The associations were comparable among men (OR: 1.20, 95% CI: 1.01–1.43) and women (OR: 1.29, 95% CI: 1.02–1.63). We also examined the potential nonlinear relationship using restricted cubic spines and found that the relationship was almost linear. Conclusions: Our analysis showed that higher perceived stress was associated with higher risks of CVDs among adults. Future studies are warranted to clarify the biological mechanisms and shed light on these associations.
背景:感知压力在心血管疾病(CVD)的发病机制中起着重要作用。在中国人群中,他们与心血管疾病的关系研究较少。本研究旨在调查在中国深圳进行的一项基于人群的调查中,感知压力与明确的心血管疾病之间的关系。方法:在社区调查中,我们从中国深圳的8个社区招募了2287名18岁及以上的参与者。使用改良的中文版感知压力量表评估感知压力,该量表包含14个项目和一个5分的Likert量表。心血管疾病,包括冠心病、心力衰竭和心房颤动,从电子健康记录中确定,并由家庭医生确认。潜在的混杂因素包括年龄、性别、教育程度、职业、吸烟和饮酒习惯。采用多变量逻辑回归模型来估计关联的大小。结果:总体而言,参与者的平均感知压力得分为37.2(标准误差:7.2,范围:14-70)。CVDs的患病率为2.7%。在控制了年龄、性别、教育程度、职业、吸烟和饮酒习惯后,感知压力评分越高,患心血管疾病的风险越高(比值比[OR]:1.25,95%置信区间[CI]:1.01–1.55)。男性(OR:1.20,95%CI:1.01–1.43)和女性(OR:1.29,95%CI:1.02–1.63)之间的相关性可比几乎是线性的。结论:我们的分析表明,在成年人中,感知压力越高,患心血管疾病的风险越高。未来的研究有必要澄清生物学机制并阐明这些关联。
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引用次数: 0
A narrative review on obstructive sleep apnea in China: A sleeping giant in disease pathology 中国阻塞性睡眠呼吸暂停研究述评:疾病病理学中的沉睡巨人
Q4 Psychology Pub Date : 2022-10-01 DOI: 10.4103/hm.hm_49_22
Yuxi Wei, Yu Liu, N. Ayas, I. Laher
We review the aspects of obstructive sleep apnea (OSA), which is the most common respiratory disorder of sleep in China. Approximately 176 million people in China have apnea/hypopnea index ≥5/h, ranking first among the ten countries with the highest prevalence rates. Two-thirds of patients do not receive treatment at all or withdraw after only brief treatment in a survey nested in two centers in China. Drowsiness and progressive cognitive impairment related to OSA decrease work performance and add to workplace errors and accidents. Many patients with OSA remain undiagnosed. Untreated OSA increases the risk of developing cardiovascular diseases and metabolic diseases. Undiagnosed and untreated OSA patients place a great burden on healthcare costs and services, and thus enormous economic burdens across most countries across the world, due to the global epidemic of obesity, an important contributor to OSA. Continuous positive airway pressure is the first-line treatment for OSA in China; however, adherence levels are poor. Effective and less labor-intensive methods that improve adherence need to be further investigated. Traditional Chinese medicine and acupuncture are promising treatments but with unproven efficacy.
我们综述了阻塞性睡眠呼吸暂停(OSA)的各个方面,OSA是中国最常见的睡眠呼吸系统疾病。中国约有1.76亿人呼吸暂停/低通气指数≥5/h,在患病率最高的十个国家中排名第一。在中国两个中心进行的一项调查中,三分之二的患者根本没有接受治疗,或者只接受了短暂的治疗就退出了治疗。与OSA相关的嗜睡和进行性认知障碍会降低工作表现,并增加工作失误和事故。许多OSA患者仍未得到诊断。未经治疗的OSA会增加患心血管疾病和代谢性疾病的风险。由于肥胖的全球流行,未经诊断和治疗的OSA患者给医疗成本和服务带来了巨大负担,从而给世界上大多数国家带来了巨大的经济负担,肥胖是OSA的重要原因。在中国,持续气道正压通气是OSA的一线治疗方法;然而,依从性水平很差。需要进一步研究提高依从性的有效且劳动密集度较低的方法。中医和针灸是有前景的治疗方法,但疗效尚未得到证实。
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引用次数: 1
A case report of iatrogenic radial artery pseudoaneurysm: Avoidable complication with the need of early intervention 医源性桡动脉假性动脉瘤1例:可避免的并发症需要早期干预
Q4 Psychology Pub Date : 2022-10-01 DOI: 10.4103/hm.hm_17_22
Anshuman Darbari, Rahul Sharma, Rahul Dev, Ruhi Sharma
It is crucial to clinically differentiate true aneurysms from pseudoaneurysms. Here, we are reporting a case of postintervention, iatrogenic distal radial artery pseudoaneurysm, which was successfully managed surgically. The present case scenario signifies the clinical features of pseudoaneurysm and relevant discussion with early treatment needs for this iatrogenic complication.
临床上区分真动脉瘤和假动脉瘤是至关重要的。在此,我们报告了一例介入治疗后的医源性桡骨远端动脉假性动脉瘤,该瘤已通过手术成功治疗。目前的病例说明了假性动脉瘤的临床特征,并对这种医源性并发症的早期治疗需求进行了相关讨论。
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引用次数: 0
Does psychosocial stress lead to spontaneous coronary artery dissection? A review of the evidence 心理压力会导致自发性冠状动脉夹层吗?证据审查
Q4 Psychology Pub Date : 2022-10-01 DOI: 10.4103/hm.hm_36_22
S. Rabkin
Spontaneous coronary artery dissection (SCAD) is the acute development of a false lumen within the coronary artery wall by the spontaneous formation of an intramural hematoma which may compromise coronary (blood) flow by compression of the true lumen. Psychological factors have been implicated in its pathophysiology, but a synthesis of available data has not been previously undertaken. A literature search was conducted with the terms coronary artery dissection or spontaneous coronary artery dissection AND the terms psychological stress, anxiety, or depression. Initial studies in the field reported that psychological stress, anxiety, or depression was associated with SCAD and that acute stress may have a role in producing the SCAD. Recent studies with control groups of either acute coronary syndromes or acute myocardial infarction have produced discordant results. A meta-analysis of these studies, in this review, using a fixed effects model, showed that there was no significant association between SCAD and either moderate-to-high psychological stress or moderate-to-severe depression. However, one study reported that patients with SCAD were two-fold more likely to have experienced an emotional precipitant in the 24 h prior to the event. Assessment of patients with SCAD found long-term psychological consequences, and in some cases similar to posttraumatic stress disorder. In conclusion, chronic psychological stress, anxiety, or depression is not associated with the development of SCAD, however acute emotional stress may be a factor precipitating SCAD in some patients. Further research is necessary to examine the biological basis for SCAD and how acute stress might play a role in its pathogenesis.
自发性冠状动脉夹层(SCAD)是指由于壁内血肿的自发形成而导致冠状动脉壁内假管腔的急性发展,这种血肿可能会通过压缩真管腔而影响冠状动脉(血液)流动。心理因素与它的病理生理学有关,但以前没有对现有数据进行综合。文献检索使用术语冠状动脉夹层或自发性冠状动脉夹层以及术语心理压力、焦虑或抑郁。该领域的初步研究报告称,心理压力、焦虑或抑郁与SCAD有关,急性压力可能在产生SCAD中发挥作用。最近对急性冠状动脉综合征或急性心肌梗死对照组的研究产生了不一致的结果。在这篇综述中,使用固定效应模型对这些研究进行的荟萃分析表明,SCAD与中度至高度心理压力或中度至重度抑郁症之间没有显著关联。然而,一项研究报告称,SCAD患者在事件发生前24小时内经历情绪激动的可能性高出两倍。对SCAD患者的评估发现了长期的心理后果,在某些情况下类似于创伤后应激障碍。总之,慢性心理压力、焦虑或抑郁与SCAD的发展无关,但急性情绪压力可能是一些患者诱发SCAD的因素。需要进一步研究SCAD的生物学基础,以及急性应激如何在其发病机制中发挥作用。
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引用次数: 0
Impact of Sleep on Cardiovascular Health: A Narrative Review 睡眠对心血管健康的影响:叙述性综述
Q4 Psychology Pub Date : 2022-07-01 DOI: 10.4103/hm.hm_29_22
O. Sum-ping, Y. Geng
Sleep is a universal biological function but remains poorly understood and a relatively new field of science and medicine. Over the past decade, there have been rapidly accumulating scientific and clinical data around sleep, including the effects of various sleep aspects on cardiovascular health. Much of the research in the field has focused on sleep-disordered breathing, particularly obstructive sleep apnea. However, other sleep pathologies including hypersomnolence disorders, sleep-related movement disorders, and parasomnia disorders have been linked with cardiovascular health. Other areas of sleep, such as sleep duration, timing, and circadian rhythms, also have a demonstrated association with heart health. In this review, we provide an updated summary of the literature connecting sleep and cardiovascular disease.
睡眠是一种普遍的生物功能,但人们对它的理解仍然很差,它是一个相对较新的科学和医学领域。在过去的十年里,人们迅速积累了有关睡眠的科学和临床数据,包括各种睡眠方面对心血管健康的影响。该领域的大部分研究都集中在睡眠呼吸紊乱,特别是阻塞性睡眠呼吸暂停。然而,其他睡眠病理,包括嗜睡障碍、睡眠相关运动障碍和睡眠障碍,也与心血管健康有关。睡眠的其他方面,如睡眠持续时间、时间和昼夜节律,也与心脏健康有关。在这篇综述中,我们提供了有关睡眠和心血管疾病的文献的最新摘要。
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引用次数: 1
Effects of Perceived Stress with Musculoskeletal Pain in Hong Kong 感知压力对香港肌肉骨骼疼痛的影响
Q4 Psychology Pub Date : 2022-07-01 DOI: 10.4103/hm.hm_20_22
H. Wing, A. Low, Joey Lam
Objective: Previous psychological research has been made on the role of perceived stress on musculoskeletal pain among adolescents and people working in different job sectors. However, no research has been made on this subject toward the Chinese population and especially the Hong Kong population. Hence, the objective of this research is to evaluate the effects and relationship between perceived stress and musculoskeletal pain and identify the statistical reasoning results of the research through looking into the specific situation in Hong Kong. Methods: In this research, data from Perceived Stress Scale-14 and a self-made pain questionnaire on perceived stress and musculoskeletal pain were collected from the patients of a registered chiropractor in Hong Kong to provide an in-depth study of how musculoskeletal pain correlated with perceived stress and how an individual's mental health would further be affected by both subjects among the Hong Kong population. Results: The findings of the research indicated that perceived stress is correlated with a combination of rather than one type of musculoskeletal pain and there is a significant correlation between one's posture, musculoskeletal pain, and psychological distress. In addition, in terms of the situation in Hong Kong; the working lifestyle and the prevalence of sedentary lifestyle may act as a risk factor on the results related to one's posture being correlated to musculoskeletal pain and perceived stress. Conclusion: It is hoped that this research could enlighten people working in the clinical psychology and chiropractor industries in Hong Kong on the subject of perceived stress and musculoskeletal pain and inform psychology researchers from other countries the situation regarding bodily pain and perceived stress in Hong Kong.
目的:对青少年和不同职业人群的肌肉骨骼疼痛的知觉压力作用进行了心理学研究。然而,并没有针对中国人口,特别是香港人口进行这方面的研究。因此,本研究的目的是通过结合香港的具体情况,评估感知压力与肌肉骨骼疼痛之间的影响和关系,并确定研究的统计推理结果。方法:本研究以香港某注册脊医患者为研究对象,采用“压力感知量表-14”及自制压力感知与肌肉骨骼疼痛问卷,深入研究压力感知与肌肉骨骼疼痛的关系,以及压力感知对个体心理健康的影响。结果:研究结果表明,感知压力与肌肉骨骼疼痛的组合相关,而不是一种肌肉骨骼疼痛,一个人的姿势、肌肉骨骼疼痛和心理困扰之间存在显著的相关性。此外,就香港的情况而言;工作生活方式和久坐生活方式的流行可能是一个风险因素,其结果与一个人的姿势与肌肉骨骼疼痛和感知压力相关。结论:希望本研究能启发香港临床心理学及脊医业者对压力感知及肌肉骨骼疼痛的认识,并让其他国家的心理学研究者了解香港的身体疼痛及压力感知的情况。
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引用次数: 0
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Heart and Mind
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