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Thyroidectomy in elderly ; is it safe? 老年人甲状腺切除术;安全吗?
Pub Date : 2022-12-31 DOI: 10.47723/kcmj.v18i3.878
Mumtaz Khudhur Hanna Alnaser, Z. Kamal, W. Wardia, Bashar Hazim Basheer
Background: The prevalence of thyroid nodules rise with age and different data available about the risks of thyroid surgery in old age people. In general, old age could be a predictor of perioperative mortality and morbidity. The aim of this study is to prove if there is increased risk accompanying thyroidectomy in elderly patients.Subjects and Methods: Prospective study of one surgeon of study sample undergoing thyroid surgery at Al-Kindy teaching hospital and Saint Raphael hospital .This study was including two groups; group (A) involved patients 65 years and older, group (B) involved patients below 65 years old who were subjected to thyroidectomy. Taking in consideration histopathology results, indications of surgery (compressive symptoms, suspicious or confirmed malignancy, toxic goiter and recurrent goiter) and complications (including rates of temporary and permanent hypocalcaemia, temporary and permanent RLN paralysis, postoperative hematoma, wound infection and seroma), in addition to the risk of perioperative mortality. Results: There were 574 patients below 65 years and 127 elderly patients (>=65 years) who underwent thyroidectomy between January 2015 and December of 2018. There were no deaths in either group; no one had bilateral RLN paralysis. Old age patients had a lower frequency of complications in comparison to the younger counterparts, including transient hypocalcaemia (3.1% vs 14.8%, respectively) and temporary RLN injury (0% vs 0.69%, respectively), in addition to permanent RLN injury (0% vs 0.34%, respectively).Conclusions: Thyroidectomy in elderly is safe as compared to younger patients regarding perioperative complications
背景:甲状腺结节的患病率随着年龄的增长而上升,关于老年人甲状腺手术的风险有不同的数据。一般来说,年龄可能是围手术期死亡率和发病率的预测因子。本研究的目的是证明老年患者甲状腺切除术是否会增加风险。对象和方法:前瞻性研究,研究样本为一名在Al-Kindy教学医院和Saint Raphael医院接受甲状腺手术的外科医生。A组为65岁及以上的患者,B组为65岁以下行甲状腺切除术的患者。考虑组织病理学结果、手术指征(压迫症状、可疑或确诊的恶性肿瘤、中毒性甲状腺肿和复发性甲状腺肿)和并发症(包括暂时性和永久性低钙血症、暂时性和永久性RLN麻痹、术后血肿、伤口感染和血肿),以及围手术期死亡风险。结果:2015年1月至2018年12月,本院共有574例65岁以下患者行甲状腺切除术,127例老年患者(>=65岁)行甲状腺切除术。两组均无死亡病例;没有人出现双侧RLN瘫痪。与年轻患者相比,老年患者的并发症发生率较低,包括短暂性低钙血症(分别为3.1%对14.8%)和暂时性RLN损伤(分别为0%对0.69%),以及永久性RLN损伤(分别为0%对0.34%)。结论:在围手术期并发症方面,老年人甲状腺切除术比年轻人安全
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引用次数: 0
The Association between CRP Levels with Comorbidities, Species, and Complications of Severe Malaria CRP水平与严重疟疾合并症、种类和并发症的关系
Pub Date : 2022-12-31 DOI: 10.47723/kcmj.v18i3.867
Salih Abdelwahab, Abdelsalam MA Nail, G. Modawe
Background: Malaria remains a leading cause of mortality in sub-Saharan Africa (including Sudan). C-reactive protein (CRP) is useful as   a marker of severity in malaria. African studies have shown that serum CRP levels correlate with parasite burden and complications in malaria, especially falciparum. However, there are no data on CRP levels in Sudanese malaria patients.This study aims to evaluate the association between CRP levels with comorbidities, species, and complications of severe malariaSubjects and Methods: A cross-sectional study enrolled 65 severe malaria patients at Khartoum state hospitals during the period from April to June2021. Manifestations of severe malaria were defined according to WHO criteria. Data regarding demographics, presenting symptoms & signs, laboratory investigations, complications, length of hospital stay and outcomes were collected. CRP was classified as elevated when the measured level was >10 mg/l.Results: Among 65 patients, 33(50.8%) were females and 32(49.2%) were males, and mean age was 48±21 years. The main manifestation of severe malaria diagnosis criteria was anemia in 26(40%) patients. Most of the patients had density 1+ (n=53; 81.5%) and were infected by P. falciparum (n=61; 93.8%). The overall case fatality rate for malaria was 8% (n=15 patients). The mean of CRP was 72±57 mg/L and 84% (n=55) of patients had elevated levels above 10 mg/L (ranged from 10-100 mg/L in 52%, and above 100 mg/L in 32%). The elevated CRP levels were significantly DM (P= 0.048), high malaria parasite density in blood film (P= 0.001), P. falciparum (P= 0.33), presence of complications (P= 0.001) and death (P= 0.003)Conclusion: Elevated CRP levels were found in a considerable proportion of severe malaria patients. CRP is an effective biomarker in assessing malaria severity and poor prognosis in term of complications development and mortality.
背景:在撒哈拉以南非洲(包括苏丹),疟疾仍是造成死亡的主要原因。C反应蛋白(CRP)可作为疟疾严重程度的标志物。非洲研究表明,血清CRP水平与疟疾,尤其是恶性疟原虫的寄生虫负担和并发症相关。然而,没有关于苏丹疟疾患者CRP水平的数据。本研究旨在评估CRP水平与严重疟疾合并症、物种和并发症之间的关系。受试者和方法:一项横断面研究纳入了2021年4月至6月期间喀土穆州立医院的65名严重疟疾患者。根据世界卫生组织的标准确定了严重疟疾的表现。收集了有关人口统计学、症状和体征、实验室调查、并发症、住院时间和结果的数据。结果:65例患者中,女性33例(50.8%),男性32例(49.2%),平均年龄48±21岁。26名(40%)患者的贫血是严重疟疾诊断标准的主要表现。大多数患者的密度为1+(n=53;81.5%),并感染恶性疟原虫(n=61;93.8%)。疟疾的总病死率为8%(n=15名患者)。CRP的平均值为72±57 mg/L,84%(n=55)的患者的CRP水平高于10 mg/L(52%为10-100 mg/L,32%为100 mg/L以上)。CRP水平升高的是DM(P=0.048)、血膜中高疟原虫密度(P=0.001)、恶性疟原虫(P=0.033)、并发症(P=0.001和死亡(P=0.003)。结论:在相当大比例的重症疟疾患者中发现CRP水平升高。CRP是评估疟疾严重程度和并发症发展和死亡率的不良预后的有效生物标志物。
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引用次数: 0
Pulmonary CT findings in Patients Recovered from COVID-19 Pneumonia COVID-19肺炎恢复期患者肺部CT表现
Pub Date : 2022-12-31 DOI: 10.47723/kcmj.v18i3.828
Sura Abass Fadhil, Muna Abdulghani
Background: The COVID-19 infection is a more recent pandemic disease all over the world and studying the pulmonary findings on survivors of this disease has lately commenced.Objective: We aimed to estimate the cumulative percentage of whole radiological resolution after 3 months from recovery and to define the residual chest CT findings and exploring the relevant affecting factors.Subjects and Methods: Patients who had been previously diagnosed with COVID-19 pneumonia confirmed by RT-PCR test and had radiological evidence of pulmonary involvement by Chest CT during the acute illness were included in the present study. The radiological data of chest CT scan of all patients were collected and analyzed after recovery (confirmed by negative RT- PCR) three months after their initial diagnosis of having COVID 19 pneumonia.Results: A total of 40 patients who had a second CT scans were assessed; there were 27 (67.5%) male and 13 (32.5%) female, with a mean age of 40.3 years old. The collective percentage of whole radiological resolution was 65% (26 patients). Patients >40 years old showed a significantly lower cumulative percentage of complete radiological resolution than patients ≤40 years old at the 3 months follow-up. The predominant patterns of abnormalities observed at discharge were ground-glass opacity (GGO), fibrous stripe and reticular opacities.Conclusion: Lung findings in COVID-19 pneumonia patients can be resolved completely during medium-term follow up with no sequelae. The older age and co-morbidities are the main significant risk factors for residual radiological findings of COVID-19 disease.
背景:COVID-19感染是最近在世界范围内发生的大流行疾病,最近开始研究该疾病幸存者的肺部检查结果。目的:评估患者康复后3个月的累积放射全分辨率,明确胸部残余CT表现,探讨相关影响因素。对象与方法:本研究纳入经RT-PCR检测证实的既往诊断为COVID-19肺炎且急性发病期间胸部CT有肺部受累影像学证据的患者。所有患者在首次诊断为COVID - 19肺炎3个月后恢复(经RT- PCR阴性证实),收集胸部CT扫描资料并进行分析。结果:共评估了40例进行第二次CT扫描的患者;男性27例(67.5%),女性13例(32.5%),平均年龄40.3岁。26例患者放射学全分辨率65%。在3个月的随访中,年龄≤40岁的患者放射学完全消退的累积百分比明显低于年龄≤40岁的患者。出院时观察到的主要异常模式是磨玻璃样混浊(GGO),纤维条纹和网状混浊。结论:COVID-19肺炎患者的肺部病变可在中期随访中完全解决,无后遗症。老年和合并症是COVID-19残留放射学表现的主要重要危险因素。
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引用次数: 0
Changing the Trends in Surgery during the COVID-19 Times: An Experience from the Eastern Uttar Pradesh State, India 新冠肺炎时期外科手术趋势的变化:印度北方邦东部的经验
Pub Date : 2022-12-31 DOI: 10.47723/kcmj.v18i3.870
P. Pandey, S. Bharat, Ashutosh Gupta
Background: The COVID-19 pandemic has an immense effect not only on the social and economic lives of people but also on the surgical lives of surgeons, residents, nursing staff, and patients as well as ground level staff. Amidst this COVID pandemic, emergency surgeries were being done but at a decreased rate, whereas elective cases depended on the will of hospitals, surgeons, and patients. Study aims to promulgate a "Neo–Surgical Check Box" by amalgamating the WHO surgical checklist and the results obtained from the questionnaires.Subjects and Methods: After receiving ethical clearance from the Institute Ethical Committee, an online questionnaire with 50 questions divided into three sections was distributed to 235 surgeons in Uttar Pradesh.Results:Two hundred and eight surgeons had responded, out of which 154 were male and 54 were female. Only 41.4% (86) were actually conducting the surgery. The emergency surgery rate was 60.3%, whereas 18.6% of elective surgeries were done, 11.8% of surgeries were avoided, and the rate of minimal access surgery was 9.3%.Conclusion: The "Neo-Surgical Check Box" will not only increase the number of surgeries per day but also provide protection to the healthcare workers while handling not only COVID-positive patients but also any airborne communicable diseases.
背景:新冠肺炎大流行不仅对人们的社会和经济生活产生了巨大影响,而且对外科医生、住院医生、护理人员、患者和基层工作人员的手术生活也产生了巨大的影响。在这场新冠肺炎疫情中,紧急手术正在进行,但速度有所下降,而选择性病例则取决于医院、外科医生和患者的意愿。该研究旨在通过合并世界卫生组织手术检查表和问卷调查结果来发布“新外科检查箱”。受试者和方法:在获得研究所伦理委员会的伦理许可后,向北方邦的235名外科医生分发了一份包含50个问题的在线问卷,分为三个部分。结果:208名外科医生做出了回应,其中154名为男性,54名为女性。只有41.4%(86)的人真正进行了手术。急诊手术率为60.3%,择期手术率为18.6%,避免手术率为11.8%,结论:“新手术复选框”不仅可以增加每天的手术次数,还可以为医护人员提供保护,同时不仅可以处理新冠肺炎阳性患者,还可以处理任何空气传播的传染病。
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引用次数: 0
Molecular Microbiology in Clinical Practice: Current and Future Applications 分子微生物学在临床实践中的应用现状与展望
Pub Date : 2022-12-31 DOI: 10.47723/kcmj.v18i2.857
Tracy Biney-Assan, M. Kron
Technological advances have yielded new molecular biology-based methods for the diagnosis of infectious diseases.  The newest and most powerful molecular diagnostic tests are available at regional and national reference laboratories, as well as at specialized centers that are certified to conduct metagenomic testing.  Metagenomic assays utilize advances in DNA extraction technology, DNA sequence library construction, high throughput DNA sequencing and automated data analysis to identify millions of individual strands of DNA extracted from clinical samples.  At present, metagenomic assays are only possible at a small number of special research, academic and commercial laboratories.  Continued research in human and pathogen genomic organization and host-pathogen interactions, represent important future goals that will maximize the information obtained from metagenomic assays.  To illustrate the power and limitations of metagenomics, we report on a previously healthy 27 year old woman with work related exposure to ill animals, and who developed a rapidly progressive, severe diffuse interstitial pneumonitis that ultimately ended in the need for a double lung transplant.   Metagenomic testing on DNA extracted from pleural fluid and nasopharyngeal swabs demonstrated the presence of expected normal bacterial flora along with some unexpected herpesvirus and non-HIV retroviral elements integrated into the patients DNA.  Although no specific pathogen was ultimately identified to explain this patient’s severe disease, the sample preparation and data analysis methods detailed herein illustrate the powerful benefits and limitations of metagenomic testing.
技术进步产生了新的基于分子生物学的传染病诊断方法。最新、最强大的分子诊断测试可在地区和国家参考实验室以及经认证可进行宏基因组测试的专业中心进行。宏基因组分析利用DNA提取技术、DNA序列库构建、高通量DNA测序和自动化数据分析的进步来识别从临床样本中提取的数百万条DNA。目前,宏基因组分析只能在少数特殊研究、学术和商业实验室进行。对人类和病原体基因组组织以及宿主-病原体相互作用的持续研究,代表着重要的未来目标,将最大限度地利用宏基因组分析获得的信息。为了说明宏基因组学的力量和局限性,我们报道了一名先前健康的27岁女性,她与工作有关,接触了生病的动物,并患上了快速进展的严重弥漫性间质性肺炎,最终需要进行双肺移植。从胸腔液和鼻咽拭子中提取的DNA的宏基因组测试表明,患者DNA中存在预期的正常菌群,以及一些意想不到的疱疹病毒和非HIV逆转录病毒成分。尽管最终没有确定具体的病原体来解释该患者的严重疾病,但本文详细介绍的样本制备和数据分析方法说明了宏基因组检测的强大优势和局限性。
{"title":"Molecular Microbiology in Clinical Practice: Current and Future Applications","authors":"Tracy Biney-Assan, M. Kron","doi":"10.47723/kcmj.v18i2.857","DOIUrl":"https://doi.org/10.47723/kcmj.v18i2.857","url":null,"abstract":"Technological advances have yielded new molecular biology-based methods for the diagnosis of infectious diseases.  The newest and most powerful molecular diagnostic tests are available at regional and national reference laboratories, as well as at specialized centers that are certified to conduct metagenomic testing.  Metagenomic assays utilize advances in DNA extraction technology, DNA sequence library construction, high throughput DNA sequencing and automated data analysis to identify millions of individual strands of DNA extracted from clinical samples.  At present, metagenomic assays are only possible at a small number of special research, academic and commercial laboratories.  Continued research in human and pathogen genomic organization and host-pathogen interactions, represent important future goals that will maximize the information obtained from metagenomic assays.  To illustrate the power and limitations of metagenomics, we report on a previously healthy 27 year old woman with work related exposure to ill animals, and who developed a rapidly progressive, severe diffuse interstitial pneumonitis that ultimately ended in the need for a double lung transplant.   Metagenomic testing on DNA extracted from pleural fluid and nasopharyngeal swabs demonstrated the presence of expected normal bacterial flora along with some unexpected herpesvirus and non-HIV retroviral elements integrated into the patients DNA.  Although no specific pathogen was ultimately identified to explain this patient’s severe disease, the sample preparation and data analysis methods detailed herein illustrate the powerful benefits and limitations of metagenomic testing.","PeriodicalId":34748,"journal":{"name":"mjlh klyh Tb lkndy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47516227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gingival Pigmentation Pattern in Correlation to Skin Color in a Group of Kurdish People in Sulaimani City 苏莱曼尼市一群库尔德人的牙龈色素沉着模式与肤色的关系
Pub Date : 2022-12-31 DOI: 10.47723/kcmj.v18i3.874
S. Amin, S. H. Azeez
Background: Melanin pigmentation of the gingiva appears in all ethnicities. Excessive pigmentation is an esthetic concern that has increased awareness about depigmentation procedures. This epidemiological study aims to find the correlation between skin color and gingival pigmentation in Sulaimani Governorate, Kurdistan/Iraq.Subjects and Methods: A total of 820 apparently healthy and non-smokers, including 338 males and 482 females with healthy gingiva, aged between (18-40 years old) were enrolled in this study. Clinical examination on the participants’ gingivae was performed to assess color, and the distribution of pigmentations. Afterward the of participants skin color were visually examined and divided into six groups according to the Fitzpatrick scale.Results: Skin color of (53%) of our participants was medium to light brown. Most of the pigmentations were observed in the attached gingiva and interdental papilla (26.83%) and least being in the marginal gingiva and interdental papilla (9.27%). A statistically significant correlation was found between the participants’ skin color, and the intensity of their gingival pigmentations  Conclusion: Darker-skinned subjects haveeavieringival pigmentation compared toair-skinned people in Sulaimani Governorate, Kurdistan/ Iraq. The intensity of gingival pigmentation increases with age with the highest rate of gingival pigmentation was in the upper and lower second premolar to premolar area.
背景:黑色素沉着的牙龈出现在所有种族。过度色素沉着是一种美学问题,它提高了人们对色素沉着程序的认识。这项流行病学研究旨在发现伊拉克库尔德斯坦苏莱曼尼省的肤色与牙龈色素沉着之间的相关性。受试者和方法:共有820名明显健康和非吸烟者,包括338名男性和482名患有健康牙龈的女性,年龄在18-40岁之间。对参与者的牙龈进行临床检查,以评估颜色和色素沉着的分布。之后,对参与者的肤色进行视觉检查,并根据Fitzpatrick量表将其分为六组。结果:我们的参与者(53%)的皮肤颜色为中等至浅棕色。色素沉着主要发生在附着的牙龈和齿间乳头(26.83%),最少发生在边缘牙龈和齿际乳头(9.27%),结论:在库尔德斯坦/伊拉克苏莱曼尼省,与空气皮肤的人相比,深色皮肤的受试者有更多的牙龈色素沉着。牙龈色素沉着的强度随着年龄的增长而增加,其中牙龈色素沉着率最高的是第二前磨牙至前磨牙的上部和下部区域。
{"title":"Gingival Pigmentation Pattern in Correlation to Skin Color in a Group of Kurdish People in Sulaimani City","authors":"S. Amin, S. H. Azeez","doi":"10.47723/kcmj.v18i3.874","DOIUrl":"https://doi.org/10.47723/kcmj.v18i3.874","url":null,"abstract":"Background: Melanin pigmentation of the gingiva appears in all ethnicities. Excessive pigmentation is an esthetic concern that has increased awareness about depigmentation procedures. This epidemiological study aims to find the correlation between skin color and gingival pigmentation in Sulaimani Governorate, Kurdistan/Iraq.\u0000Subjects and Methods: A total of 820 apparently healthy and non-smokers, including 338 males and 482 females with healthy gingiva, aged between (18-40 years old) were enrolled in this study. Clinical examination on the participants’ gingivae was performed to assess color, and the distribution of pigmentations. Afterward the of participants skin color were visually examined and divided into six groups according to the Fitzpatrick scale.\u0000Results: Skin color of (53%) of our participants was medium to light brown. Most of the pigmentations were observed in the attached gingiva and interdental papilla (26.83%) and least being in the marginal gingiva and interdental papilla (9.27%). A statistically significant correlation was found between the participants’ skin color, and the intensity of their gingival pigmentations  \u0000Conclusion: Darker-skinned subjects haveeavieringival pigmentation compared toair-skinned people in Sulaimani Governorate, Kurdistan/ Iraq. The intensity of gingival pigmentation increases with age with the highest rate of gingival pigmentation was in the upper and lower second premolar to premolar area.","PeriodicalId":34748,"journal":{"name":"mjlh klyh Tb lkndy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49244606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative study on Various Tube Voltages and Contrast Media Doses in CT Pulmonary Angiography to detect Pulmonary Thromboembolism 不同管电压和造影剂剂量在CT肺血管造影中检测肺血栓栓塞的比较研究
Pub Date : 2022-12-31 DOI: 10.47723/kcmj.v18i3.808
Shaymaa Khalid Abdul-Qader, A. A. Fadhil
Background: Lowering the amount of iodinated contrast material and tube voltage may increase pulmonary artery opacification and thrombus identification without compromising picture quality.Objectives: To explore the efficiency of using lower tube voltage and a lower contrast medium dose for conducting computed tomography for pulmonary angiography (CTPA) aiming to increase its accuracy in detecting pulmonary thromboembolism (PTE).Subjects and Methods:100 patients scheduled for CTPA with a preoperative diagnosis of PTE were grouped into two: group A, (50 patients) got 1 mL/kg at 120 kV and group B, (50 patients) received 0.5 mL/kg at 80 kV.The technique of bolus tracking was implemented.Values of midpoint of multiple pulmonary artery divisions were used to assess attenuation.Significant values are those that exceed 300 Hounsfield units (HU). The dosage of radiation received by the patient, defined as the effective dose, was compared between groups.Results: Total mean attenuationdata for the pulmonary arteries have shown to be substantially greater in group-B compared to group-A (39110.4HU vs. 335.97.9HU, P=0.001). Moreover, total dose length product (DLP) values were substantially lower in group-B (934.9 mGy.cm vs. 384.443 mGy.cm, P=0.001). While effective dose values have shown to be significantly lower in group-B (2.90.3 mSv vs. 13.21.8 mSv, P 0.001).Conclusion: Low-kilovoltage technique and low quantity of iodinated contrast are useful in conducting (CTPA) with high accuracy in detection of pulmonary thromboembolism.
背景:在不影响图像质量的情况下,降低碘化造影剂的量和显像管电压可能会增加肺动脉混浊和血栓识别。目的:探讨使用较低的管电压和较低的造影剂剂量进行肺动脉造影计算机断层扫描(CTPA)的效率,以提高其检测肺血栓栓塞症(PTE)的准确性。受试者和方法:将100名术前诊断为PTE的CTPA患者分为两组:a组,(50例患者)在120kV下给药1mL/kg,B组(50例)在80kV下给药0.5mL/kg。使用多个肺动脉分区的中点值来评估衰减。显著值是指超过300 Hounsfield单位(HU)的值。将患者接受的辐射剂量(定义为有效剂量)在各组之间进行比较。结果:B组肺动脉的总平均衰减数据明显高于A组(39110.4HU对335.97.9HU,P=0.001)。此外,B组的总剂量-长度乘积(DLP)值明显较低(934.9 mGy.cm vs.384.443 mGy.ccm,P=0.001)。而B组的有效剂量值显著较低(2.90.3 mSv vs.13.21.8 mSv,P=0.001血栓栓塞。
{"title":"Comparative study on Various Tube Voltages and Contrast Media Doses in CT Pulmonary Angiography to detect Pulmonary Thromboembolism","authors":"Shaymaa Khalid Abdul-Qader, A. A. Fadhil","doi":"10.47723/kcmj.v18i3.808","DOIUrl":"https://doi.org/10.47723/kcmj.v18i3.808","url":null,"abstract":"Background: Lowering the amount of iodinated contrast material and tube voltage may increase pulmonary artery opacification and thrombus identification without compromising picture quality.\u0000Objectives: To explore the efficiency of using lower tube voltage and a lower contrast medium dose for conducting computed tomography for pulmonary angiography (CTPA) aiming to increase its accuracy in detecting pulmonary thromboembolism (PTE).\u0000Subjects and Methods:100 patients scheduled for CTPA with a preoperative diagnosis of PTE were grouped into two: group A, (50 patients) got 1 mL/kg at 120 kV and group B, (50 patients) received 0.5 mL/kg at 80 kV.The technique of bolus tracking was implemented.Values of midpoint of multiple pulmonary artery divisions were used to assess attenuation.Significant values are those that exceed 300 Hounsfield units (HU). The dosage of radiation received by the patient, defined as the effective dose, was compared between groups.\u0000Results: Total mean attenuationdata for the pulmonary arteries have shown to be substantially greater in group-B compared to group-A (39110.4HU vs. 335.97.9HU, P=0.001). Moreover, total dose length product (DLP) values were substantially lower in group-B (934.9 mGy.cm vs. 384.443 mGy.cm, P=0.001). While effective dose values have shown to be significantly lower in group-B (2.90.3 mSv vs. 13.21.8 mSv, P 0.001).\u0000Conclusion: Low-kilovoltage technique and low quantity of iodinated contrast are useful in conducting (CTPA) with high accuracy in detection of pulmonary thromboembolism.","PeriodicalId":34748,"journal":{"name":"mjlh klyh Tb lkndy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41364253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lifestyle Medicine: A Promising tool to Restoring Health 生活方式医学:恢复健康的有希望的工具
Pub Date : 2022-12-31 DOI: 10.47723/kcmj.v18i3.932
E. Hameed, Laith Thamer Al-Ameri
Lifestyle Medicine is the application of evidence-based lifestyle approaches for the prevention, treatment, and even the reversal of lifestyle-related chronic diseases such as diabetes, hypertension, heart disease, obesity, polycystic ovarian diseases, dementia, arthritis, and cancers
生活方式医学是基于证据的生活方式方法的应用,用于预防、治疗甚至逆转与生活方式相关的慢性疾病,如糖尿病、高血压、心脏病、肥胖、多囊卵巢疾病、痴呆、关节炎和癌症
{"title":"Lifestyle Medicine: A Promising tool to Restoring Health","authors":"E. Hameed, Laith Thamer Al-Ameri","doi":"10.47723/kcmj.v18i3.932","DOIUrl":"https://doi.org/10.47723/kcmj.v18i3.932","url":null,"abstract":"Lifestyle Medicine is the application of evidence-based lifestyle approaches for the prevention, treatment, and even the reversal of lifestyle-related chronic diseases such as diabetes, hypertension, heart disease, obesity, polycystic ovarian diseases, dementia, arthritis, and cancers","PeriodicalId":34748,"journal":{"name":"mjlh klyh Tb lkndy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44405758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Efficiency of Corn Solution as a Cytological Fixative in Buccal Smear 玉米溶液作为口腔涂片细胞学固定剂的效果
Pub Date : 2022-12-31 DOI: 10.47723/kcmj.v18i3.839
Jalal Eldein Mahmoud Nour Wara, Mohammed Abdulelah Abuzeid Abdulrahem, Tasabeeh Mustafa Alzain Salem, Waad Akram Albager Mohammed, Walaa Tamim Eldar Khalaf Allah Abuzeid, Maha Hamid Omer Bushara, Amna Mohammed Hassan, A. Idris
Background: Corn Syrup is food syrup higher of carbohydrate, depending on grade. The study aimed to assess efficiency of Corn syrup as cytological fixative.Subjects and methods: This was laboratory based study, it has been conducted at Elrazi University included   apparently 30 healthy students have been involved in this study.Results: Out of 30 smears fixed with 95% alcohol, 76.7% (n=23) shows excellent nuclear stain, 23.3% (n= 7)   shows good nuclear stain. 70% (n=21) show excellent cytoplasmic stain, 26.7% (n=8) shows good cytoplasmic stain, 3.3% (n=1) shows poor cytoplasmuc stain.   Out of 30 smears fixed with corn solution, 60% (n=18) shows excellent nuclear stain, 40% (n=12) good nuclear stain, 3.3 % (n=1) shows excellent cytoplasmic stain, 83.3% (n=25) shows good cytoplasmic stain, 13.3% (n=4) shows bad cytoplasmic stain.Conclusion: Study concluded that Corn syrup can be used as cytological fixative alternatively to 95% ethyl alcohol.
背景:玉米糖浆是高碳水化合物的食品糖浆,取决于等级。本研究旨在评价玉米糖浆作为细胞学固定剂的效果。对象和方法:这是一项基于实验室的研究,在Elrazi大学进行,包括30名健康的学生参与了这项研究。结果:95%乙醇固定30张涂片,76.7% (n=23)为核染色优,23.3% (n= 7)为核染色良。70% (n=21)细胞质染色优良,26.7% (n=8)细胞质染色良好,3.3% (n=1)细胞质染色不良。在30张玉米溶液固定的涂片中,60% (n=18)为核染色优,40% (n=12)为核染色优,3.3% (n=1)为胞质染色优,83.3% (n=25)为胞质染色优,13.3% (n=4)为胞质染色差。结论:玉米糖浆可替代95%乙醇作为细胞学固定剂。
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引用次数: 0
Evaluation of Streptocin SH3, a Bacteriocin produced by Streptococcus sanguinis isolated from Human Dental Plaque 从人牙菌斑中分离的血链球菌产生的一种细菌素——链球菌SH3的评价
Pub Date : 2022-12-31 DOI: 10.47723/kcmj.v18i3.843
Shahad Fadhil Al-Taie, Muna T. Al- Musawi, Zaid S. Rasheed
Background: Bacteriocin is a peptidic toxin has many advantages to bacteria in their ecological niche and has strong antibacterial activity. Objective: The aim of this study was to evaluation of bacteriocin using Streptococcus sanguinis isolated from human dental caries. Subjects and Methods: Thirty five streptococcus isolates were diagnosed and tested for their production of bacteriocin, and then the optimal conditions for production of bacteriocin were determined.  After that, the purification of bacteriocin was made partially by ammonium sulfate at 95% saturation levels, followed by and gel filtration chromatography using Sephadex G-50 column. Finally, physical characteristics were also studied and determined the bacteriocin stability.Results: Among all streptococcal isolates, the S. sanguinis SH3 isolate with batter antimicrobial activity was selected, and used in further experiments. The optimum conditions for bacteriocin production were in Todd Hewitt broth (THB) supplemented with 1% glucose at 37°C for 24h under anaerobic conditions and inoculum size of (1.2 ˟ 109CFU/ml) and pH 7, where the inhibition zone diameter reached to 29 mm against Enterococcus faecalis. The purified bacteriocin had high inhibitory activity against S. pneumoniae, S. pyogenes, E. faecalis, E. faecium and  Leuconostoc mesenteroides. Streptocin SH3 keeps its effectiveness within the pH range 3-10, and temperature until 80ºC for 20 min.Conclusion: Bacteriocin produced from S. sanguinis has high activity against many pathogens and has high stability over wide ranges of temperature and pH, which makes it a good alternative in the medical and food preservation fields
背景:细菌素是一种肽毒素,对细菌的生态位有许多优势,具有很强的抗菌活性。目的:研究从人龋齿中分离的血链球菌对细菌素的影响。对象与方法:对35株分离链球菌进行产菌素检测,确定产菌素的最佳工艺条件。然后用硫酸铵在95%饱和度下部分纯化细菌素,然后用Sephadex G-50柱进行凝胶过滤层析。最后对其物理特性进行了研究,并确定了细菌素的稳定性。结果:在所有链球菌分离株中,筛选出抑菌活性较好的血链球菌SH3分离株,用于进一步的实验。产菌素的最佳条件为:在37℃、接种量(1.2˟109CFU/ml)、pH为7的厌氧条件下,添加1%葡萄糖的Todd Hewitt肉汤(THB)发酵24h,对粪肠球菌的抑菌带直径可达29 mm。纯化后的细菌素对肺炎链球菌、化脓性链球菌、粪肠球菌、粪肠球菌和肠系膜白色球菌具有较高的抑制活性。结论:从血链球菌中提取的细菌素对多种病原菌具有较高的活性,且在较宽的温度和pH范围内具有较高的稳定性,在医疗和食品保鲜领域具有良好的应用前景
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引用次数: 0
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