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Recuperemos nuestra esencia 恢复我们的本质
Q4 Medicine Pub Date : 2021-12-27 DOI: 10.31157/archneurosciencesmex.v26i4.328
R. Revuelta-Gutiérrez
The National Institute of Neurology and Neurosurgery is one of the great Institutions of the health sector, which has been and is a source of pride for the country and I want to emphasize that the creation of this Institute was due to a great character in world Neurosurgery, the teacher Don Manuel Velasco Suárez; It is very important to know that this institution was conceived and created last century and inaugurated in 1964 to be a unique work in the world, since with the great visionary mind of Don Manuel, I place in the same physical space the three great branches of Neurosciences: Neurosurgery, Neurology and Psychiatry, which did not exist.
国家神经病学和神经外科研究所是卫生部门的伟大机构之一,一直是国家的骄傲,我想强调的是,这个研究所的建立要归功于世界神经外科的伟大人物,唐·曼努埃尔·贝拉斯科老师Suárez;重要的是要知道,这个机构是在上个世纪构思和创建的,并于1964年落成,是世界上独一无二的工作,因为有了唐·曼努埃尔伟大的远见卓识,我把神经科学的三个伟大分支:神经外科、神经病学和精神病学放在同一个物理空间里,而这三个分支当时并不存在。
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引用次数: 0
Primary alveolar soft tissue sarcoma of the central nervous system. Case report 原发性中枢神经系统肺泡软组织肉瘤。病例报告
Q4 Medicine Pub Date : 2021-11-30 DOI: 10.31157/archneurosciencesmex.v26i4.289
Eliezer Villanueva-Castro, M. Sangrador-Deitos, Jorge F Aragón-Arreola, Gerardo Cano-Velázquez, J. Gómez-Amador, M. Tena-Suck
Background: Alveolar soft part sarcoma (ASPS) is a rare, slow-growing soft tissue tumor with uncertain etiology; it is considered among the least common sarcomas, representing 0.2-1% of these cases in large studies. These tumors usually appear during childhood or young patients, with predominance in females. Case description: We introduce the case of ASPS in a 62-year-old man, who presented with 7 months of progressive headache and diplopia. The brain MRI showed an infiltrative lesion in the anterior fossa that extended to the right orbital roof. The possibility of metastasis was ruled out.  The patient underwent resection of the tumor with posteriorly good visual and neurologic recovery. Histologic characterization demonstrated homogeneous eosinophilic cells with a solid, vascularized pattern, cells with large and binucleated nucleoli, and vessels with endothelial and myoepithelial hyperplasia; numerous apoptotic bodies and mitosis figures were also present, but no necrosis. On immunohistochemistry, cells exhibited positive CD56, NSE in membrane form, and slight myogenin; vessels were strongly positive for myogenin, myoglobin, CD34, CD31, factor VIII, vimentin, and nestin as well as for HBM45, CD20, GFAP, and S-100; cytokeratin showed fine extracellular and intracellular filaments; GATA and TTF1 were negative.  Some clear cells were observed to be positive for CD68. The piece was diagnosed as a non-meningeal alveolar sarcoma of the soft tissue with solid pattern. Discussion and Conclusion: This case corresponds to the second tumor of this kind presented at our institution, the first one reported, and perhaps, one of the oldest patients to develop it worldwide.
背景:肺泡软组织肉瘤(Alveolar soft part sarcoma, ASPS)是一种罕见的、生长缓慢的软组织肿瘤,病因不明;它被认为是最不常见的肉瘤之一,在大型研究中占这些病例的0.2% -1%。这些肿瘤通常出现在儿童或年轻患者,以女性为主。病例描述:我们介绍一名62岁男性的ASPS病例,他表现为7个月的进行性头痛和复视。脑部MRI显示前窝浸润性病变延伸至右眶顶。转移的可能性已被排除。患者术后视力及神经功能恢复良好,行肿瘤切除术。组织学特征显示均质嗜酸性细胞呈实心血管化模式,核仁大且双核,血管内皮和肌上皮增生;可见大量凋亡小体和有丝分裂图,但未见坏死。免疫组化显示细胞CD56阳性,膜状NSE阳性,肌原素轻微;血管中肌原蛋白、肌红蛋白、CD34、CD31、因子VIII、vimentin和巢蛋白以及HBM45、CD20、GFAP和S-100呈强阳性;细胞角蛋白呈胞外和胞内细丝;GATA、TTF1均为阴性。部分透明细胞CD68阳性。片被诊断为非脑膜肺泡肉瘤的软组织实型。讨论与结论:该病例是我们医院报告的第二例此类肿瘤,也是第一例报道的肿瘤,可能是世界上最古老的肿瘤患者之一。
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引用次数: 0
Comparaciones entre el control motor de insectos y mamíferos 昆虫和哺乳动物运动控制的比较
Q4 Medicine Pub Date : 2021-11-12 DOI: 10.31157/archneurosciencesmex.vi.320
Mireya Alcaraz-Zubeldia
Esta reflexión está inspirada en el artículo “Neurobiología del control motor en Insectos”. La presencia de un generador central de patrones (GCP) en mamíferos es difícil de generalizar. Sin embargo, se discuten una serie de analogías funcionales entre insectos y mamíferos, entre las que destaca el patrón trípode de la marcha
这一反思的灵感来自《昆虫运动控制的神经生物学》这篇文章。在哺乳动物中存在中央模式发生器(GCP)是很难概括的。然而,我们讨论了昆虫和哺乳动物之间的一些功能相似之处,包括三脚架步态模式。
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引用次数: 0
Efecto anticonvulsivo y antidepresivo del extracto etanólico de hojas de Annona reticulata en rata 番荔枝叶乙醇提取物对大鼠抗惊厥、抗抑郁的作用
Q4 Medicine Pub Date : 2021-10-18 DOI: 10.31157/archneurosciencesmex.v26i3.218
Veronica Baron Flores, E. Martínez-Rodríguez, D. Hernández-López, M. Romero-Paredes, M. E. González-Trujano, A. Diaz-Ruiz, Camilo Ríos-Castañeda
La depresión, la ansiedad y la epilepsia son afecciones del Sistema Nervioso Central (SNC) que causan sufrimiento y morbilidad entre la población mexicana. Si bien existen fármacos para su terapéutica, en ocasiones éstos resultan ineficaces y promueven efectos adversos que conllevan a la falta de apego por parte del paciente. Especies del género Annona son utilizadas en la medicina tradicional Mexicana por sus propiedades inhibitorias del SNC, de los cuales ya se han reportado sus propiedades como ansiolítico-sedantes y anticonvulsivos, además de sus propiedades como anticancerígenos, antioxidantes y anti-inflamatorios. El objetivo de este estudio consistió en realizar un cernimiento de los posibles efectos inhibidores en el SNC de la especie Annona reticulata (A. reticulata) sobre modelos experimentales en roedores. Método: A. reticulata se utilizó preparada como un extracto etanólico, para evaluar sus efectos como ansiolitico y antidepresivo en la prueba de nado forzado y como anticonvulsivo en la prueba de crisis convulsivas inducidas con pentilentetrazol en ratas, también se probó su efecto como ansiolítico en la prueba de enterramiento de canicas. Imipramina, valproato de sodio y diazepam se utilizaron como fármacos de referencia, respectivamente. Resultados: A. reticulata redujo la conducta depresiva, además aumentó la latencia y disminuyó la severidad de las crisis convulsivas, y disminuyó la respuesta tipo ansiedad de los ratones. Conclusión: este estudio da evidencia preclínica de las propiedades como antidepresivo, ansiolítico y anticonvulsivo de las hojas de A. reticulata, reforzando su potencial en la búsqueda de alternativas para afecciones del SNC.
抑郁、焦虑和癫痫是中枢神经系统(cns)的疾病,在墨西哥人口中造成痛苦和疾病。虽然有治疗药物,但它们有时是无效的,并促进不良反应,导致患者缺乏依恋。番荔枝属植物因其抑制中枢神经系统的特性而被用于墨西哥传统医学,除了具有抗癌、抗氧化和抗炎的特性外,还报道了其抗焦虑、镇静和抗惊厥的特性。本研究的目的是在啮齿动物的实验模型中确定网状番荔枝(A.网状番荔枝)对中枢神经系统可能的抑制作用。方法:a . reticulata准备像etanólico提取物,用于评估其ansiolitico之类的效果和抗抑郁强迫游泳测试,并在测试的镇咳危机convulsivas诱导大鼠与pentilentetrazol等的影响,也得到证实ansiolítico掩埋测试的大理石雕塑。分别以丙咪嗪、丙戊酸钠和地西泮为对照药物。结果:网状A. reticulata降低了小鼠的抑郁行为,增加了潜伏期,降低了癫痫发作的严重程度,降低了小鼠的焦虑样反应。结论:本研究提供了抗抑郁、抗焦虑和抗惊厥特性的临床前证据,加强了其寻找中枢神经系统疾病替代方案的潜力。
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引用次数: 0
Síndrome acento extranjero en Esclerosis Múltiple, revisión y presentación de un caso. 多发性硬化症的外国口音综合征,个案回顾与介绍。
Q4 Medicine Pub Date : 2021-10-15 DOI: 10.31157/archneurosciencesmex.v26i3.225
V. Barriga-Maldonado, Diego Rubén Posadas-Pinto, Miriam Cruz-Guillermo, Diana Citlalli López-Hernández, I. Treviño-Frenk
Introducción: El Síndrome de Acento Extranjero (SAE) una entidad rara, los pacientes desarrollan cambios en el ritmo y tono del habla (prosodia), percibidos como un acento diferente al de su lengua natal. Existen tres tipos de SAE: neurogénico, psicogénico y mixto. El SAE es infrecuente en EM, y aún más como síntoma debut. Objetivo. Revisión del SAE, tipos, fisiopatología y presentación en EM y evolución. Desarrollo. El SAE Las lesiones corticales en EM se correlacionan con deterioro cognitivo, discapacidad motora, síntomas psiquiátricos, alteraciones del lenguaje, síntomas conversivos y crisis epilépticas. La mayoría de los casos publicados de SAE han sufrido lesión en el hemisferio dominante, en corteza prerrolándica y áreas adyacentes, áreas motoras frontales de asociación, en putamen, ganglios basales, fosa posterior (protuberancia, cerebelo), por diferentes etiologías siendo la más frecuente la vascular. Compartimos un caso clínico: mujer, 44 años debuta con SAE interpretado inicialmente como infarto cerebral en quien finalmente se concluyó el diagnóstico de esclerosis múltiple. Ha tenido mejoría parcial de los síntomas posterior a rehabilitación fonoaudiológica.  Conclusiones. SAE es una presentación infrecuente de debut de EM. Debe considerarse la etiología desmielinizante en pacientes jóvenes, con escasos o sin factores de riesgo vascular y apoyarse en estudios complementarios de neuroimágenes.
简介:外国口音综合征(SAE)是一种罕见的疾病,患者在说话的节奏和音调(韵律)上发生变化,被认为是与母语不同的口音。有三种类型的SAE:神经源性、心理源性和混合性。在多发性硬化症中,SAE是罕见的,尤其是作为一种初始症状。目标。回顾SAE,类型,病理生理学和表现在ms和进化。发展。ms的皮质损伤与认知障碍、运动障碍、精神症状、语言障碍、转换症状和癫痫发作相关。大多数已发表的SAE病例均在显性半球、前倾皮层及邻近区域、前额运动区、壳核、基底神经节、后窝(突起、小脑)发生损伤,病因不同,最常见的是血管病变。我们分享了一个临床病例:44岁的女性首次出现SAE,最初被解释为脑梗死,最终被诊断为多发性硬化症。他在语言康复后的症状有部分改善。结论。在这种情况下,患者可能会出现神经退行性疾病,如多发性硬化症(ms),这是一种罕见的多发性硬化症首次表现。
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引用次数: 0
José María Morelos y Pavón frente a un caso de Trastorno Psicótico Compartido: Nocupétaro, Intendencia de Valladolid, Nueva España (1799-1801). jose maria Morelos y pavon面对一个共同的精神病病例:nocupetaro,巴利亚多利德,新西班牙(1799-1801)。
Q4 Medicine Pub Date : 2021-10-15 DOI: 10.31157/archneurosciencesmex.v26i3.281
César Campos-Farfán
Resumen El trastorno psicótico compartido o folie à deux es un síndrome psiquiátrico de presentación más frecuente de lo que tradicionalmente se creía o consignaba la literatura especializada hasta hace algunos pocos años. Dos factores han contribuido de manera determinante para que empiece a ser considerado como una entidad clínicamente significativa: a) una mejor evaluación familiar y del entorno social de los enfermos diagnosticados como psicóticos y, b) la identificación precisa de los casos, muchos de los cuales son rescatados de la literatura y la historia, a veces con más carácter anecdótico que científico. Es importante señalar que entre más se hurga en el pasado, se ha encontrado que es tan antiguo como lo puede ser la humanidad misma. En el presente trabajo de investigación se describe un caso que presenció unos de los héroes más significativos del continente americano y el mundo occidental. La importancia radica no sólo en la trascendencia del personaje involucrado, sino que además se trata de una variante clínica raramente descrita denominada psicosis alucinatoria inducida.    
最后,我们分析了在西班牙和葡萄牙进行的一项研究的结果,该研究的目的是确定一种新的治疗方法,该方法基于一种新的治疗方法,该方法基于一种新的治疗方法,该方法基于一种新的治疗方法,该方法基于一种新的治疗方法。两个因素促成了以决定性的方式开始被视为实体临床意义:(a)更好地评估患者的家庭和社会环境的诊断疾病,(b)确定准确的病例,其中有许多是获救文学和历史,有时比科学轶事。值得注意的是,人们对过去的研究越多,就会发现它和人类本身一样古老。在这篇研究论文中,我们描述了一个案例,见证了美洲大陆和西方世界最重要的英雄之一。它的重要性不仅在于所涉及的角色的重要性,而且还在于它是一种罕见的临床变体,被称为诱发幻觉精神病。
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引用次数: 0
Nocardia abscessus brain abscess in an immunocompetent patient with bronchiectasis 免疫功能正常的支气管扩张患者的脑脓肿
Q4 Medicine Pub Date : 2021-10-04 DOI: 10.31157/archneurosciencesmex.v26i3.264
A. Camiro-Zúñiga, A. Rodriguez-Alcocer, Juan Steta-Orozco, Javier Tejeda-Maldonado, Luis Espinosa-Aguilar, Maria Alejandra González-Patiño, Estefanía Murrieta-Peralta, J. Romero-Figueroa, J. Calleja-Castillo
A 56 year-old woman presented with new onset focal seizure with a history of bronchiectasis. Brain abscess was diagnosed by magnetic resonance. She was confirmed to be immunocompetent and had histoplasmosis, tuberculosis, and infective endocarditis ruled out. Nocardia sp. was isolated from the brain abscess and identified as Nocardia abscessus complex by 16S rRNA sequencing. She was discharged on trimethoprim/sulfamethoxazole. Nocardia sp. is a cause of brain abscesses in patients with underlying pulmonary structural disease like bronchiectasis. Nocardia identification is of paramount importance as it is not treated with empiric antimicrobial therapy.
一个56岁的妇女提出了新发作局灶性癫痫病史的支气管扩张。脑脓肿经磁共振诊断。她被证实免疫功能正常,排除了组织浆菌病、肺结核和感染性心内膜炎。从脑脓肿中分离到诺卡菌,经16S rRNA测序鉴定为脓肿诺卡菌复合体。出院时使用甲氧苄啶/磺胺甲恶唑。诺卡菌是支气管扩张等肺结构性疾病患者脑脓肿的病因。诺卡菌鉴定是至关重要的,因为它不是经验性抗菌治疗。
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引用次数: 0
Erasing “the purely arbitrary line”. 抹去“纯粹任意的界线”。
Q4 Medicine Pub Date : 2021-09-30 DOI: 10.31157/archneurosciencesmex.v26i3.318
S. Castillo-Torres, A. J. Lees
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引用次数: 0
Prevalence of attention deficit/hyperactivity disorder in Mexican university students 墨西哥大学生注意缺陷/多动障碍的患病率
Q4 Medicine Pub Date : 2021-09-30 DOI: 10.31157/archneurosciencesmex.v26i3.280
M. G. Yáñez-Téllez, Veronica Danahe Villaseñor-Valadez, Belén Prieto-Corona, Ana Natalia Seubert-Ravelo
Introduction: Attention-Deficit/Hyperactivity Disorder (ADHD) in adulthood causes relevant deterioration in daily functioning. Specifically, in educational scenarios, complications including an elevated rate of failed courses and desertion have been found. The reported prevalence of ADHD in adults varies widely, therefore studying specific populations becomes important. Objective: to determine the prevalence of ADHD in students at a public university using screening tools to determine the presence of current and retrospective symptomatology during childhood and to describe their sociodemographic characteristics. Method: the study was conducted with a probabilistic sample of undergraduate students (N = 1837), to whom the Adult Self Report Scale for ADHD (ASRS-6) and the Wender Utha Rating Scale (WURS) were administered to determine current and childhood ADHD symptoms. Results: the prevalence of ADHD in the studied population was 16.2%, with a significantly higher frequency in males (22.14%) than in females (13%). ADHD was most prevalent in Biology students (23.7%) and least in Nursery students (9.9%). Discussion and conclusion: results indicate a higher frequency of ADHD in Mexican undergraduate students than that reported in adult populations of other countries, but consistent with previous reports of Mexican undergraduate students and children. The association of ADHD and difficulties in academic, work, and social achievement in the studied population should be further investigated.
成人的注意力缺陷/多动障碍(ADHD)会导致相关的日常功能恶化。具体来说,在教育方面,已经发现了包括不及格率和逃学率上升在内的并发症。报道的ADHD在成人中的患病率差异很大,因此研究特定人群变得很重要。目的:利用筛查工具确定儿童时期当前和回顾性症状的存在,并描述其社会人口学特征,确定公立大学学生ADHD的患病率。方法:本研究以本科生为随机样本(N = 1837),采用成人ADHD自我报告量表(ASRS-6)和Wender Utha评定量表(WURS)确定其当前和儿童期ADHD症状。结果:研究人群ADHD患病率为16.2%,其中男性(22.14%)明显高于女性(13%)。ADHD以生物系学生最多(23.7%),幼儿园学生最少(9.9%)。讨论和结论:结果表明,墨西哥本科生的ADHD发病率高于其他国家的成年人,但与之前关于墨西哥本科生和儿童的报道一致。ADHD与研究人群在学业、工作和社会成就方面的困难之间的关系有待进一步调查。
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引用次数: 1
L’Etranger, the absurdism of a Nobel prize and the description of an unknown psychiatric disorder. 《陌生人》,诺贝尔奖的荒诞,以及对一种未知精神疾病的描述。
Q4 Medicine Pub Date : 2021-09-30 DOI: 10.31157/archneurosciencesmex.v26i3.284
P. García-Espinosa, José G Garza-Marichalar, S. Castillo-Torres
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引用次数: 0
期刊
Archivos de Neurociencias
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