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Advancing Musculoskeletal Care Using AI and Digital Health Applications: A Review of Commercial Solutions. 利用人工智能和数字健康应用推进肌肉骨骼护理:商业解决方案综述。
IF 1.6 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-05-30 DOI: 10.1177/15563316251341321
Johannes Pawelczyk, Moritz Kraus, Sebastian Voigtlaender, Sebastian Siebenlist, Marco-Christopher Rupp

Artificial intelligence (AI) and digital health (DH) solutions are reshaping musculoskeletal (MSK) care across diagnostics, treatment planning, workflow optimization, and administrative burden reduction. AI-enabled triage systems enhance patient flow efficiency, while automated scheduling, symptom checkers, and AI-powered virtual assistants streamline pre-visit interactions. In MSK radiographic diagnostics, AI augments imaging interpretation, enabling automated fracture detection, opportunistic screening, and quantitative imaging, improving diagnostic accuracy and standardization. Preoperative planning solutions facilitate implant templating, surgical navigation, and patient-specific instrumentation, reducing variability and enhancing surgical precision. Concurrently, digital scribes and AI-driven documentation tools alleviate administrative overhead, mitigating clinician burnout and enabling refocused patient engagement. Predictive analytics optimize treatment pathways by leveraging multimodal patient data for risk stratification and personalized decision support. However, algorithmic bias, model generalizability, regulatory hurdles, and legal ambiguities present substantial implementation barriers, necessitating rigorous validation, adaptive governance, and seamless clinical integration. The U.S. and EU regulatory landscapes diverge in their approaches to AI oversight, with the former favoring expedited market access and the latter imposing stringent compliance mandates under the EU AI Act. AI's integration into MSK care demands robust validation frameworks, standardized interoperability protocols, and dynamic regulatory pathways balancing safety and innovation. Emerging generalist foundation models, open-source large language models (LLMs), and specialized AI-driven medical applications herald a paradigm shift toward precision MSK care. These innovations will require prospective clinical validation to ensure patient benefit and mitigate risk. Addressing ethical considerations, ensuring equitable access, and fostering interdisciplinary collaboration remain paramount in translating AI's potential into tangible improvements in MSK healthcare delivery.

人工智能(AI)和数字健康(DH)解决方案正在从诊断、治疗计划、工作流程优化和行政负担减轻等方面重塑肌肉骨骼(MSK)护理。支持人工智能的分诊系统提高了患者流程效率,而自动调度、症状检查器和人工智能驱动的虚拟助手简化了就诊前的互动。在MSK放射诊断中,人工智能增强了成像解释,实现了自动骨折检测、机会性筛查和定量成像,提高了诊断的准确性和标准化。术前计划解决方案有助于植入物模板、手术导航和患者特定的器械,减少可变性并提高手术精度。同时,数字抄写员和人工智能驱动的文档工具减轻了管理开销,减轻了临床医生的倦怠,并使患者重新关注。预测分析通过利用多模式患者数据进行风险分层和个性化决策支持来优化治疗途径。然而,算法偏差、模型可泛化性、监管障碍和法律模糊性构成了实质性的实施障碍,需要严格的验证、适应性治理和无缝的临床整合。美国和欧盟的监管格局在人工智能监管方面存在分歧,前者倾向于加快市场准入,后者则根据《欧盟人工智能法案》(EU AI Act)实施严格的合规要求。将人工智能集成到MSK护理中需要强大的验证框架、标准化的互操作性协议以及平衡安全和创新的动态监管途径。新兴的多面手基础模型、开源大型语言模型(llm)和专门的人工智能驱动的医疗应用预示着向精确MSK护理的范式转变。这些创新将需要前瞻性临床验证,以确保患者受益并降低风险。在将人工智能的潜力转化为MSK医疗保健服务的切实改进方面,解决伦理问题、确保公平获取和促进跨学科合作仍然至关重要。
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引用次数: 0
Large Language Models in Spine Surgery: A Promising Technology. 脊柱外科中的大型语言模型:一项有前途的技术。
IF 1.6 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-05-29 DOI: 10.1177/15563316251340696
Romil Shah, Joseph H Schwab

Large language models (LLMs) offer potential applications across medical specialties; in spine surgery, opportunities exist to enhance patient care, streamline research, and improve clinical practice. This review explores the current and potential applications of LLMs in spine surgery, assessing their possibilities and limitations across patient education, research, clinical practice, and perioperative assistance.

大型语言模型(llm)提供了跨医学专业的潜在应用;在脊柱外科,机会存在,以加强病人护理,简化研究,并改善临床实践。这篇综述探讨了llm在脊柱外科中的当前和潜在应用,评估了它们在患者教育、研究、临床实践和围手术期协助方面的可能性和局限性。
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引用次数: 0
Artificial Intelligence in the Diagnosis and Prognostication of the Musculoskeletal Patient. 人工智能在肌肉骨骼患者诊断和预测中的应用。
IF 1.6 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-05-28 DOI: 10.1177/15563316251339660
Miguel M Girod, Sami Saniei, Marisa N Ulrich, Lainey G Bukowiec, Kellen L Mulford, Michael J Taunton, Cody C Wyles

As artificial intelligence (AI) advances in healthcare, encompassing robust applications for the diagnosis and prognostication of musculoskeletal diseases, clinicians must increasingly understand the implications of machine learning and deep learning in their practice. This review article explores computer vision algorithms and patient-specific, multimodal prediction models; provides a simple framework to guide discussion on the limitations of AI model development; and introduces the field of generative AI.

随着人工智能(AI)在医疗保健领域的进步,包括在肌肉骨骼疾病的诊断和预测方面的强大应用,临床医生必须越来越多地了解机器学习和深度学习在他们的实践中的影响。这篇综述文章探讨了计算机视觉算法和针对患者的多模态预测模型;提供了一个简单的框架来指导关于人工智能模型开发局限性的讨论;并介绍了生成式人工智能领域。
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引用次数: 0
The State of Telemedicine, Telerehabilitation, and Virtual Care in Musculoskeletal Health: A Narrative Review. 远程医疗、远程康复和虚拟护理在肌肉骨骼健康中的现状:一个叙述性的回顾。
IF 1.6 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-05-28 DOI: 10.1177/15563316251341229
Mitchell A Johnson, Tyler Khilnani, Abigail Hyun, Troy B Amen, Nathan H Varady, Benedict U Nwachukwu, Joshua S Dines

Telemedicine has become an increasingly important component of musculoskeletal care, with recent advances in virtual physical examinations, enhanced patient education, and expanded access to treatment and telerehabilitation. Emerging applications of artificial intelligence, including virtual triaging and remote patient monitoring, promise to further augment telemedicine's effectiveness and scope. Despite limitations and a continued preference for in-person visits among some patients, telemedicine can be a valuable tool for musculoskeletal health practitioners, offering new ways to deliver high-quality, timely, and cost-effective care.

远程医疗已成为肌肉骨骼保健日益重要的组成部分,最近在虚拟体检、加强患者教育以及扩大获得治疗和远程康复方面取得了进展。人工智能的新兴应用,包括虚拟分诊和远程患者监护,有望进一步扩大远程医疗的有效性和范围。尽管有局限性,而且一些患者仍然倾向于亲自就诊,但远程医疗对肌肉骨骼健康从业者来说是一个有价值的工具,它提供了提供高质量、及时和具有成本效益的护理的新方法。
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引用次数: 0
Artificial Intelligence in Value-Based Health Care. 基于价值的医疗保健中的人工智能。
IF 1.6 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-05-28 DOI: 10.1177/15563316251340074
Romil Shah, Kevin J Bozic, Prakash Jayakumar

Artificial intelligence (AI) presents new opportunities to advance value-based healthcare in orthopedic surgery through 3 potential mechanisms: agency, automation, and augmentation. AI may enhance patient agency through improved health literacy and remote monitoring while reducing costs through triage and reduction in specialist visits. In automation, AI optimizes operating room scheduling and streamlines administrative tasks, with documented cost savings and improved efficiency. For augmentation, AI has been shown to be accurate in diagnostic imaging interpretation and surgical planning, while enabling more precise outcome predictions and personalized treatment approaches. However, implementation faces substantial challenges, including resistance from healthcare professionals, technical barriers to data quality and privacy, and significant financial investments required for infrastructure. Success in healthcare AI integration requires careful attention to regulatory frameworks, data privacy, and clinical validation.

人工智能(AI)通过代理、自动化和增强三种潜在机制为骨科手术提供了新的机会,以推进基于价值的医疗保健。人工智能可以通过提高卫生知识和远程监测来加强患者代理,同时通过分诊和减少专家就诊来降低成本。在自动化方面,人工智能优化了手术室调度,简化了管理任务,节省了成本,提高了效率。在增强方面,人工智能已被证明在诊断成像解释和手术计划方面是准确的,同时能够实现更精确的结果预测和个性化治疗方法。然而,实施面临着巨大的挑战,包括来自医疗保健专业人员的阻力、数据质量和隐私方面的技术障碍,以及基础设施所需的大量财务投资。医疗保健人工智能集成的成功需要仔细关注监管框架、数据隐私和临床验证。
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引用次数: 0
Orthopedic Residency Programs: What are Our Current Goals? An International Society of Orthopedic Centers (ISOC) Delphi Consensus. 骨科住院医师项目:我们当前的目标是什么?国际骨科中心协会(ISOC)德尔菲共识。
IF 1.6 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-05-28 DOI: 10.1177/15563316251337359
David Figueroa, Luis Moya, José Arteaga, Alex Vaisman, Mathias Bostrom, Carolina Acuña, Domenico Alesi, Fernando Radice, Francisco Figueroa, Felipe Toro, Meir Liebergall, Mark Stegeman, Magnus Tagil, Mario Lenza, Parag Sancheti, Amar Ranawat, Rafael Calvo, Rodrigo Guiloff, Laura Robbins, Sebastian Irarrazaval, Stefano Zaffagnini, Tobias Jung, Tobias Winkler
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引用次数: 0
Artificial Intelligence and Digital Applications in Musculoskeletal Healthcare: Ready or Not, Here It Comes! 人工智能和数字应用在肌肉骨骼保健:准备好了吗,它来了!
IF 1.6 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-05-20 DOI: 10.1177/15563316251341314
Kyle N Kunze
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引用次数: 0
Competencies of Large Language Models About Piriformis Syndrome: Quality, Accuracy, Completeness, and Readability Study. 梨状肌综合征大语言模型的能力:质量、准确性、完整性和可读性研究。
IF 1.6 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-05-20 DOI: 10.1177/15563316251340697
Burak Tayyip Dede, Muhammed Oğuz, Bülent Alyanak, Fatih Bağcıer, Mustafa Turgut Yıldızgören

Background:The proliferation of artificial intelligence has led to widespread patient use of large language models (LLMs). Purpose: We sought to characterize LLM responses to questions about piriformis syndrome (PS). Methods: On August 15, 2024, we asked 3 LLMs-ChatGPT-4, Copilot, and Gemini-to respond to the 25 most frequently asked questions about PS, as tracked by Google Trends. We evaluated the accuracy and completeness of the responses according to the Likert scale. We used the Ensuring Quality Information for Patients (EQIP) tool to assess the quality of the responses and assessed readability using Flesch-Kincaid Reading Ease (FKRE) and Flesch-Kincaid Grade Level (FKGL) scores. Results: The mean completeness scores of the responses obtained from ChatGPT, Copilot, and Gemini were 2.8 ± 0.3, 2.2 ± 0.6, and 2.6 ± 0.4, respectively. There was a significant difference in the mean completeness score among LLMs. In pairwise comparisons, ChatGPT and Gemini were superior to Copilot. There was no significant difference between the LLMs in terms of mean accuracy scores. In readability analyses, no significant difference was found in terms of FKRE scores. However, a significant difference was found in FKGL scores. A significant difference between LLMs was identified in the quality analysis performed according to EQIP scores. Conclusion: Although the use of LLMs in healthcare is promising, our findings suggest that these technologies need to be improved to perform better in terms of accuracy, completeness, quality, and readability on PS for a general audience.

背景:人工智能的扩散导致患者广泛使用大型语言模型(llm)。目的:我们试图描述LLM对梨状肌综合征(PS)问题的反应。方法:在2024年8月15日,我们询问了3位法学硕士(chatgpt -4, Copilot和gemini),以回答谷歌Trends跟踪的关于PS的25个最常见问题。我们根据李克特量表评估回答的准确性和完整性。我们使用确保患者质量信息(EQIP)工具来评估应答的质量,并使用Flesch-Kincaid阅读难度(FKRE)和Flesch-Kincaid分级水平(FKGL)评分来评估可读性。结果:ChatGPT、Copilot和Gemini的平均完整度评分分别为2.8±0.3、2.2±0.6和2.6±0.4。llm的平均完整性评分有显著差异。在两两比较中,ChatGPT和Gemini优于Copilot。在平均准确性得分方面,llm之间没有显著差异。在可读性分析中,在FKRE得分方面没有发现显著差异。然而,FKGL评分有显著差异。在根据EQIP评分进行的质量分析中,llm之间存在显著差异。结论:虽然llm在医疗保健中的应用很有前景,但我们的研究结果表明,这些技术需要改进,以便在PS上为普通受众提供更好的准确性、完整性、质量和可读性。
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引用次数: 0
Artificial Intelligence and Musculoskeletal Surgical Applications. 人工智能与肌肉骨骼外科应用。
IF 1.6 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-05-20 DOI: 10.1177/15563316251339596
Felix C Oettl, Bálint Zsidai, Jacob F Oeding, Kristian Samuelsson

Artificial intelligence (AI) has emerged as a transformative force in orthopedic surgery. Potentially encompassing pre-, intra-, and postoperative processes, it can process complex medical imaging, provide real-time surgical guidance, and analyze large datasets for outcome prediction and optimization. AI has shown improvements in surgical precision, efficiency, and patient outcomes across orthopedic subspecialties, and large language models and agentic AI systems are expanding AI utility beyond surgical applications into areas such as clinical documentation, patient education, and autonomous decision support. The successful implementation of AI in orthopedic surgery requires careful attention to validation, regulatory compliance, and healthcare system integration. As these technologies continue to advance, maintaining the balance between innovation and patient safety remains crucial, with the ultimate goal of achieving more personalized, efficient, and equitable healthcare delivery while preserving the essential role of human clinical judgment. This review examines the current landscape and future trajectory of AI applications in orthopedic surgery, highlighting both technological advances and their clinical impact. Studies have suggested that AI-assisted procedures achieve higher accuracy and better functional outcomes compared to conventional methods, while reducing operative times and complications. However, these technologies are designed to augment rather than replace clinical expertise, serving as sophisticated tools to enhance surgeons' capabilities and improve patient care.

人工智能(AI)已经成为整形外科的一股变革力量。它可以处理复杂的医学成像,提供实时手术指导,并分析大型数据集,以预测和优化结果,潜在地涵盖术前、术中和术后过程。人工智能在骨科亚专科的手术精度、效率和患者预后方面都有所提高,大型语言模型和人工智能代理系统正在将人工智能的应用范围从手术应用扩展到临床文档、患者教育和自主决策支持等领域。人工智能在骨科手术中的成功实施需要仔细关注验证、法规遵从性和医疗保健系统集成。随着这些技术的不断发展,保持创新和患者安全之间的平衡仍然至关重要,最终目标是实现更加个性化、高效和公平的医疗保健服务,同时保留人类临床判断的基本作用。本文回顾了人工智能在骨科手术中应用的现状和未来轨迹,重点介绍了技术进步及其临床影响。研究表明,与传统方法相比,人工智能辅助手术具有更高的准确性和更好的功能结果,同时减少了手术时间和并发症。然而,这些技术旨在增强而不是取代临床专业知识,作为提高外科医生能力和改善患者护理的复杂工具。
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引用次数: 0
Amino Acid Supplementation May Help Prevent Muscle Wasting After Orthopedic Surgery, but Additional Studies Are Warranted: A Systematic Review of Randomized Clinical Trials. 补充氨基酸可能有助于防止骨科手术后肌肉萎缩,但需要进一步的研究:随机临床试验的系统回顾。
IF 1.3 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-05-01 Epub Date: 2025-01-08 DOI: 10.1177/15563316241308265
Elizabeth Brown, Samantha A Mohler, Shiloah A Kviatkovsky, Lindsay E Blake, J Ryan Hill, Jeffrey B Stambough, Paul M Inclan

Background: Essential amino acid (EAA) supplementation, including conditionally essential amino acid (CEAA) and branched-chain amino acids (BCAA) supplementation, has been suggested as a mechanism to optimize patient outcomes by counteracting the atrophy associated with orthopedic procedures. Purpose: We sought to investigate the effect of EAA supplementation in the perioperative period on patients undergoing orthopedic and spine surgery, specifically whether it is associated with (1) reductions in postoperative muscle atrophy and (2) improved postoperative function including range of motion, strength, and mobility. Methods: We conducted a systematic review of the literature. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were used, and the protocol was registered in the Prospective Register of Systematic Reviews (PROSPERO) database (CRD42023447774). Studies of interest were prospective, placebo-controlled, randomized clinical trials (RCTs) published between 2002 and 2023 evaluating the impact of EAA supplementation on patients undergoing orthopedic and spine surgery. Results: Ten RCTs evaluating EAA supplementation in trauma, adult reconstruction, and spine surgery were identified; half of these focused on adult reconstruction. The EAA supplementation dose (3.4-20 g), frequency (daily to 3 times per day), and duration (14-49 days) varied widely across studies. Seven studies reported parameters relating to muscle size and/or composition, with 3 studies reporting superior muscle size/composition in patients receiving perioperative EAA supplementation, when compared with controls. Three studies reported favorable mobility outcomes for patients receiving EAA. Meta-analysis was prohibited by variation in measurement and outcome variables across the studies. Conclusions: Pooled data from level I studies supports the use of EAA, BCAA, and CEAA supplementations across several orthopedic subspecialties. However, significant heterogeneity exists in the quantity, duration, and content of EAA administered. Further prospective studies are needed to determine optimal/standardized parameters for supplementation.

背景:补充必需氨基酸(EAA),包括补充条件性必需氨基酸(CEAA)和支链氨基酸(BCAA),已被认为是一种通过对抗骨科手术相关萎缩来优化患者预后的机制。目的:我们试图研究围手术期补充EAA对骨科和脊柱手术患者的影响,特别是它是否与(1)术后肌肉萎缩的减少和(2)术后功能的改善有关,包括运动范围、力量和活动能力。方法:我们对文献进行了系统的回顾。采用系统评价和荟萃分析首选报告项目(PRISMA)指南,该方案已在系统评价前瞻性注册(PROSPERO)数据库(CRD42023447774)中注册。相关研究是2002年至2023年间发表的前瞻性、安慰剂对照、随机临床试验(rct),评估补充EAA对骨科和脊柱手术患者的影响。结果:10项rct评估了EAA补充在创伤、成人重建和脊柱手术中的应用;其中一半集中在成人重建上。EAA的补充剂量(3.4- 20g)、频率(每天至每天3次)和持续时间(14-49天)在不同的研究中差异很大。7项研究报告了与肌肉大小和/或组成相关的参数,其中3项研究报告了与对照组相比,接受围手术期补充EAA的患者的肌肉大小/组成更优。三项研究报告了接受EAA治疗的患者活动能力良好。由于研究中测量和结果变量的差异,禁止进行meta分析。结论:来自一级研究的汇总数据支持EAA、BCAA和CEAA补充剂在几个骨科亚专科的应用。然而,在EAA给药的数量、持续时间和内容上存在显著的异质性。需要进一步的前瞻性研究来确定补充剂的最佳/标准化参数。
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引用次数: 0
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