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Characteristics of COVID-19 Infection among Nursing Home Residents 疗养院居民新冠肺炎感染特点
Q3 Arts and Humanities Pub Date : 2020-12-31 DOI: 10.5671/CA.44.4.4
Maja Mizdrak, Tina Tičinović Kurir, Ivan Mizdrak, I. Jerković, Ante Mayer
Given high risk of infection-related mortality due to impaired immunity, elderly patients are at increased risk with COVID-19. In its diagnostic procedure clinical laboratory medicine has a pivotal role. The aim of this study was to investigate clinical and laboratory specificities in Croatian population of nursing home residents affected by coronavirus. One hundred and six residents of nursing homes that were hospitalized due to COVID-19 infection, were included in this retrospective study. Clinical and laboratory findings at three time points were extracted from medical records. There were 86 females and 20 males, with median of age 84 (min-max: 47–97) years. Patients were divided into three groups: Survivors (S), patients who are still alive (N=65), In-Hospital Non-Survivors (IHNS), patients who died from coronavirus during hospitalization (N=31) and Out-of-Hospital Non-Survivors (OHNS), patients who recovered from infection but died during the period of three months of the follow-up (N=10). We have established differences between these three groups in laboratory findings (p<0.05). At the admission, survivors had lower values of lactate dehydrogenase, aspartate transaminase, sedimentation ratio, ferritin and C-reactive protein, OHNS were in the middle, and IHNS had the highest values. Leukocytes and absolute lymphocyte count were greater in OHNS group, and same between survivors and IHNS. After 7 days, we noticed increase in leukocyte and neutrophils count among IHNS. Assessing of complete blood count, differential blood count, reactants of acute infection and combination of their ratios might predict worse outcome in nursing home residents due to coronavirus infection.
鉴于免疫功能受损导致感染相关死亡的高风险,老年患者感染COVID-19的风险增加。临床检验医学在其诊断过程中起着举足轻重的作用。本研究的目的是调查克罗地亚受冠状病毒感染的养老院居民的临床和实验室特异性。106名因COVID-19感染住院的养老院居民纳入本回顾性研究。从医疗记录中提取三个时间点的临床和实验室结果。女性86例,男性20例,年龄中位数84岁(最小-最大47 ~ 97岁)。患者分为三组:幸存者(S),仍然活着的患者(N=65),院内非幸存者(IHNS),住院期间死于冠状病毒的患者(N=31)和院外非幸存者(OHNS),感染后康复但在随访三个月期间死亡的患者(N=10)。我们确定了这三组在实验室结果上的差异(p<0.05)。入院时,存活者乳酸脱氢酶、天冬氨酸转氨酶、沉降比、铁蛋白和c反应蛋白较低,OHNS居中,IHNS最高。白细胞和绝对淋巴细胞计数OHNS组高于IHNS组,存活者与IHNS组差异无统计学意义。7天后,我们注意到IHNS的白细胞和中性粒细胞计数增加。评估全血细胞计数、差异血细胞计数、急性感染反应物及其组合比率可能会预测因冠状病毒感染导致的养老院居民预后较差。
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引用次数: 0
Model-Based Analysis of Changes in the Morphological Characteristics of Moscow Students for the Last Two Decades 近二十年来莫斯科学生形态特征变化的模型分析
Q3 Arts and Humanities Pub Date : 2020-12-31 DOI: 10.5671/CA.44.4.5
M. Negasheva, S. Zimina, I. Sineva, E. Godina
The aim of the paper is to develop a model of changes in morphological characteristics of young males and females body structure at the beginning of the 21st century. For this purpose the results of Moscow students’ annual screenings from 2000 to 2018 were analyzed (total number of 17–18-year-olds − 6,433 individuals). As a result, five factors describing the trends of changes were revealed and further analysis demonstrated variants of their values over time. An original model was developed, which reflected real morphological transformations in the body parameters of the young generation for the last 20 years. For both sex groups a trend towards macrosomia (gr. macros − big, soma- body) was revealed. For the boys some increase in linear traits was found with a decrease in muscularity. In girls, parabolic association between athletic characteristics and the year of investigation was found: the decrease in muscularity for the first decade, and its increase for the second one.
本文的目的是建立一个21世纪初年轻男性和女性身体结构形态特征变化的模型。为此,分析了2000年至2018年莫斯科学生的年度筛查结果(17-18岁的总人数为6433人)。结果,揭示了描述变化趋势的五个因素,进一步的分析表明了它们的值随时间的变化。开发了一个原始模型,反映了过去20年年轻一代身体参数的真实形态变化。对于两个性别组,都显示出巨大儿的趋势(gr.macross-big,soma-body)。对于男孩来说,随着肌肉的减少,线性特征有所增加。在女孩中,运动特征与调查年份之间存在抛物线关系:第一个十年肌肉发达度下降,第二个十年增加。
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引用次数: 1
Governance in/of Cancer Care and Stewardship in Cancer Control 癌症护理的治理和癌症控制中的管理
Q3 Arts and Humanities Pub Date : 2020-12-30 DOI: 10.5671/CA.44.4.7
M. Jelenc, M. Vidovič, Edit Marosi, P. Nagy, A. Federici, Mateja Lam
In the literature in the field of cancer care, especially in the literature concerning national cancer control programmes, the terms governance and stewardship in/of cancer care are used, but usually not explained or defined. Therefore, we planned a systematic literature review in order to find the definitions of the terms governance and stewardship in/of cancer care. It was planned to create new definitions of the mentioned terms in case of unsuccessful finds. A literature review using PubMed, Google and MeSH as well as an opportunistic search for extra articles and chapters from books and grey literature was performed. Most of the found and analysed articles did not give exact explanation of the terms governance/stewardship in/of cancer care or they cited older articles (published before the year 2000) where the terms are used mostly in the field of clinical governance or in the completely other fileds, mostly banking, economy, religion or spirituality. Therefore, it was decided in the working group of experts from different European countries collaborating within in the work package Governance of integrated and comprehensive cancer care in the frame of the Innovative Partnership for the Action Against Cancer Joint Action project on cancer to create new definitions which we are presenting for the first time. The new definitions will facilitate the understanding of the leadership tasks in the area of cancer care and cancer control and will be particularly useful in the field of cancer programmes.
在癌症护理领域的文献中,特别是关于国家癌症控制方案的文献中使用了癌症护理的治理和管理,但通常没有解释或定义。因此,我们计划进行一次系统的文献综述,以找到癌症护理中的治理和管理术语的定义。计划在发现不成功的情况下为上述术语创建新的定义。使用PubMed、Google和MeSH进行了文献综述,并对书籍和灰色文献中的额外文章和章节进行了机会主义搜索。大多数被发现和分析的文章没有对癌症护理中的治理/管理术语做出确切解释,或者它们引用了较旧的文章(2000年之前发表),其中这些术语主要用于临床治理领域或完全其他的文件,主要是银行、经济、宗教或精神。因此,来自不同欧洲国家的专家组成的工作组决定,在癌症癌症联合行动创新伙伴关系项目框架内,在癌症综合综合护理治理工作包内进行合作,以创建我们首次提出的新定义。新的定义将有助于理解癌症护理和癌症控制领域的领导任务,并将在癌症方案领域特别有用。
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引用次数: 0
The Socio-Cultural Context of Breastfeeding in the Nineteenth and Twentieth Centuries 19和20世纪母乳喂养的社会文化背景
Q3 Arts and Humanities Pub Date : 2020-12-30 DOI: 10.5671/CA.44.4.8
Anđela Runjić Babić
This paper will give a historical account of breastfeeding and explain the socio-cultural context in which the shift from breastfeeding to bottle feeding occurred in the western industrialized nations in the course of the nineteenth and twentieth centuries. Whereas in the nineteenth century most infants were breastfed by the middle of the twentieth century bottle-feeding had become the norm. The growth of artificial infant feeding was related to economic conditions as well as the socio- cultural changes within the burgeoning industrial societies. Aside from the rise of infant formula industry one of the major factors that affected the decline in breastfeeding rates was the shift of breastfeeding from a natural practice into an object of medicine and science. Other cultural factors including religious beliefs, feminism and the changing roles of women within society have affected women's infant feeding choices. Throughout these socio-historical developments breastfeeding was promoted as the best option for infant health. However, concern over breastfeeding rates was also a concern over women's proper mothering behavior and a desire to control women and their mothering practices.
本文将给出母乳喂养的历史记录,并解释从母乳喂养到奶瓶喂养的转变发生在19世纪和20世纪的西方工业化国家的社会文化背景。而在19世纪,大多数婴儿是母乳喂养的,到20世纪中叶,奶瓶喂养已经成为常态。人工喂养婴儿的增长与新兴工业社会的经济条件和社会文化变化有关。除了婴儿配方奶粉工业的兴起外,影响母乳喂养率下降的一个主要因素是母乳喂养从一种自然做法转变为医学和科学的对象。其他文化因素,包括宗教信仰、女权主义和妇女在社会中角色的变化,也影响了妇女喂养婴儿的选择。在这些社会历史发展过程中,母乳喂养被认为是婴儿健康的最佳选择。然而,对母乳喂养率的关切也是对妇女适当的养育行为的关切,以及控制妇女及其养育做法的愿望。
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引用次数: 1
3D Cell Technology in Biomedical Research 生物医学研究中的三维细胞技术
Q3 Arts and Humanities Pub Date : 2020-12-13 DOI: 10.5671/ca.44.3.10
Katarina Mišković Špoljarić, Marijana Jukić, Teuta Opačak-Bernardi, L. Glavaš‐Obrovac
Traditional two dimensional cell culture has enabled great strides in biomedicine but needs to be improved to be able to keep up with the demands of modern biomedical research. 2D monolayer culture cannot replicate tissue responses and needs to be supplemented with extensive animal research. Growing cells in three dimensional scaffolds provides a more functional model for biomedical research than traditional monolayer culture. Depending on the needs and the complexity of the model there are several ways that 3D models can be initiated. Simple spheroids can be grown in low adherence plates and in hanging drops while larger spheroids and co-cultured ones need to be grown in systems with greater support such as hydro gels. The system that offers the greatest flexibility is the magnetic levitation approach. In the paper we offer a brief resume to various 3D methods and their characteristics to ease the choice of methods for implementing 3D cell culture techniques .
传统的二维细胞培养使生物医学取得了长足进步,但需要改进才能跟上现代生物医学研究的要求。2D单层培养不能复制组织反应,需要补充广泛的动物研究。在三维支架中生长细胞为生物医学研究提供了比传统单层培养更具功能的模型。根据模型的需要和复杂性,有几种方法可以启动3D模型。简单的球体可以在低粘附板和悬滴中生长,而较大的球体和共培养的球体需要在具有更大支撑的系统中生长,如水凝胶。提供最大灵活性的系统是磁悬浮方法。在本文中,我们简要介绍了各种3D方法及其特点,以便于选择实现3D细胞培养技术的方法。
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引用次数: 0
Aneurysmal Bone Cyst of the Cervical Spine 颈椎动脉瘤性骨囊肿
Q3 Arts and Humanities Pub Date : 2020-12-13 DOI: 10.5671/ca.44.3.8
Irina Bagić, D. Mužević, Gordan Reljac, Vjenceslav Vrtarić, M. Kovačević
Aneurysmal bone cyst (ABC) is a non-neoplastic locally destructive primary bone lesion mostly occurring within the first two decades of life with female predominance. Cervical spine ABCs are a very rare clinical entity with particularly demanding surgical resection limited by the involvement of nearby neurovascular structures and a risk for cervical spine instability. We present a case of a 17-year-old patient with a symptomatic ABC of the cervical spine who underwent surgical removal of the osseous lesion with good postoperative outcome. There are different therapeutic strategies for ABC management, but complete surgical removal of the cyst remains one of the most important predictors of favorable outcome, although it can be often limited, especially in the cervical region. Previously described lesions have a very high recurrence rate and therefore different additional methods, such as radiotherapy, embolization and sclerosation have been used in addition to surgical resection. Further studies are necessary for development of evidence-based treatment regimens for cervical spine ABCs in pediatric population.
动脉瘤性骨囊肿(ABC)是一种非肿瘤性局部破坏性的原发性骨病变,多发生在生命的前20年,以女性为主。颈椎abc是一种非常罕见的临床疾病,由于累及附近的神经血管结构和颈椎不稳定的风险,特别需要手术切除。我们报告了一个17岁的颈椎症状性ABC患者的病例,他接受了手术切除骨性病变,术后效果良好。对于ABC治疗有不同的治疗策略,但完全手术切除囊肿仍然是预后良好的最重要预测因素之一,尽管它通常是有限的,特别是在宫颈区域。先前描述的病变具有非常高的复发率,因此除了手术切除外,还使用了不同的附加方法,如放疗、栓塞和硬化。需要进一步研究以证据为基础的儿童颈椎abc治疗方案。
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引用次数: 1
Health-Related Concepts and Cognitive Linguistics 健康相关概念与认知语言学
Q3 Arts and Humanities Pub Date : 2020-12-13 DOI: 10.5671/ca.44.3.12
M. Raguž, Marijan Jukic, H. Roguljić
Human behavior is governed by concepts. Concepts are cognitive representations of reality. Cognitive linguistics suggests that there are cognitive models affecting the formation of concepts in human mind, such as cognitive metaphor and a prototype model. We used the example of an ancient procedure – trepanation in order to show the connection between the procedure and the concept of the skull as a container, which is a metaphor. Most important concepts in medical systems are health and disease. There is no agreement about their exact definition, although there have been many studies focusing on that. Based on the previous research, we suggest possible benefits from approaching the disease as a prototype category. In all studies so far there have always been consistencies in rating entities qualifying as a disease which is a feature of a prototype category – membership gradience. Entities perceived as diseases by respondents in studies so far have not been the same, but they share certain features. It is more likely for an entity to be considered a disease if it can lead to death, for example. In our opinion there are common core features determining disease as a cognitive category. Further cross-cultural studies could answer what features an entity needs to have in order to be considered a disease.Stressing such features could improve patients’cooperation when a new disease appears.
人的行为受概念支配。概念是对现实的认知表征。认知语言学认为,人类心理中存在着影响概念形成的认知模型,如认知隐喻和原型模型。我们使用了一个古老手术的例子——钻孔,以展示该手术与头骨作为容器的概念之间的联系,这是一个隐喻。医疗系统中最重要的概念是健康和疾病。关于它们的确切定义,目前还没有达成一致,尽管已经有许多研究聚焦于此。基于之前的研究,我们提出了将该疾病作为原型类别可能带来的好处。在迄今为止的所有研究中,对符合疾病资格的实体的评级总是一致的,这是原型类别的一个特征——成员等级。到目前为止,在研究中被受访者视为疾病的实体并不相同,但它们有某些共同的特征。例如,如果一个实体会导致死亡,那么它更有可能被视为一种疾病。在我们看来,疾病作为一个认知范畴有着共同的核心特征。进一步的跨文化研究可以回答一个实体需要具备哪些特征才能被视为一种疾病。当出现新的疾病时,强调这些特征可以改善患者的操作。
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引用次数: 0
Prognostički pokazatelji prve iponovljene hospitalizacije kod pacijenata sa srčanim zatajivanjem s reduciranomejekcijskom frakcijom lijeve klijetke 左细胞剂量减少的心力衰竭患者首次更新住院的预后指征
Q3 Arts and Humanities Pub Date : 2020-12-13 DOI: 10.5671/ca.44.3.5
Kristina Selthofer-Relatić, Jure Mirat, Kristina Kralik, Jadranka Arambašić, Anto Stažić, Matko Tomić
Heart failure with reduced ejection fraction (HFrEF) is a progressive clinical syndrome defined by changes in the myocardial structure, which lead to predominant systolic myocardial function impairment, with a left ventricle ejection of fraction ≤40%. The rehospitalization burden in HFrEF patients (pts) remains very high, with poor quality of life, increased mortality and large healthcare expenditures. In this research project, we investigated the risk factors for first and repeated hospitalization in pts with HFrEF. This retrospective study included 50 adult pts with a diagnosis of HFrEF and who were within the age range of 55 to 89 years old and of both sexes. Demographic and clinical data (HFrEF etiology, renal function parameters, complete blood count, markers of inflammation, electrocardiogram, troponin I, NTproBNP, echocardiographic parameters and comorbidities data) were collected from the pts’ medical histories. Statistical analysis was performed via Fischer’s exact test, the Shapiro-Wilk test and the Spearman correlation coefficient. This study included 70% male and 30% female HFrEF pts. Males were younger in both group of pts and had a higher incidence of rehospitalization. The most important HFrEF etiologic risk factors are arterial hypertension (82%), coronary heart disease (54%), atrial fibrillation (52%) and diabetes mellitus (40%). The most important noncardiac comorbidity related with the first HFrEF hospitalization is pneumonia (P=0.03), while progression of left ventricle systolic and diastolic dysfunction is related to rehospitalization risk (left ventricle end systolic diameter, P=0.003; diastolic dysfunction degree, P=0.04). The troponin level was associated with an increased risk of rehospitalization, but this was not statistically significant at this sample size (troponin I, p=0.10). Following the first and repeated hospitalizations of HFrEF pts, comorbidities, ageing and gender difference are crucial to HFrEF development, while echocardiographic parameters and biomarkers critically affect HFrEF rehospitalization risk.
心力衰竭伴射血分数降低(HFrEF)是一种以心肌结构改变为特征的进行性临床综合征,以收缩期心肌功能损害为主,左心室射血分数≤40%。HFrEF患者(患者)的再住院负担仍然很高,生活质量差,死亡率增加,医疗保健支出大。在本研究项目中,我们调查了HFrEF患者首次和多次住院的危险因素。这项回顾性研究包括50名诊断为HFrEF的成年患者,年龄在55至89岁之间,男女不限。从患者的病史中收集人口学和临床资料(HFrEF病因、肾功能参数、全血细胞计数、炎症标志物、心电图、肌钙蛋白I、NTproBNP、超声心动图参数和合并症数据)。采用Fischer精确检验、Shapiro-Wilk检验和Spearman相关系数进行统计分析。这项研究包括70%的男性和30%的女性HFrEF患者。两组患者中男性均较年轻,再住院率较高。最重要的HFrEF病因危险因素是动脉高血压(82%)、冠心病(54%)、心房颤动(52%)和糖尿病(40%)。与首次HFrEF住院相关的最重要的非心脏合并症是肺炎(P=0.03),而左心室收缩和舒张功能障碍的进展与再次住院风险相关(左心室收缩末期直径,P=0.003;舒张功能不全程度,P=0.04)。肌钙蛋白水平与再住院风险增加相关,但在该样本量下无统计学意义(肌钙蛋白I, p=0.10)。在HFrEF患者首次和多次住院后,合并症、年龄和性别差异对HFrEF的发展至关重要,而超声心动图参数和生物标志物对HFrEF再次住院的风险至关重要。
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引用次数: 1
Telemedicine for Diabetic Retinopathy Screening in Croatia 克罗地亚糖尿病视网膜病变筛查的远程医疗
Q3 Arts and Humanities Pub Date : 2020-12-13 DOI: 10.5671/ca.44.3.11
M. Tomić, P. Raštegorac, R. Vrabec, T. Poljičanin, D. Rahelić
Diabetic retinopathy (DR) is the leading cause of preventable blindness in working-age adults associated with devastating personal and socioeconomic consequences. The increasing use of anti-vascular endothelial growth factor (anti- VEGF) agents over the past decade and telemedicine implementation in systematic DR screening resulted in a declining trend of new blindness due to diabetes in several countries. Telemedicine is the remote delivery of healthcare services over the telecommunications infrastructure. It allows healthcare providers to evaluate, diagnose, and treat patients without the need for an in-person visit. Teleophthalmology is a telemedicine branch, mostly focused on diabetic retinopathy and retinopathy of prematurity. Screening for DR in Croatia is commonly performed annually, only by ophthalmologists using dilated slit-lamp biomicroscopic fundus examination. Due to the insufficient number of ophthalmologists and the lack of a formal call system, many diabetic patients do not perform annual screening. In an ideal DR screening model in Croatia, each diabetes center in university or general hospitals throughout Croatia (17 centers) would have one small digital fundus camera and an educated nurse who would perform dilated fundus photography. Electronic images from diabetes centers would be transferred for remote grading to the same hospitals’ ophthalmology departments or a central grading center for DR screening in Croatia. Grading for DR would be performed by an ophthalmologist, medical retina specialist. Patients would be annually invited by mail from the National Diabetes Registry to come to the nearest diabetes center for a fundus photographing and DR screening. Each patient with a positive result would be promptly referred to the medical retina specialist at the closest ophthalmology department for further examination and treatment.
糖尿病性视网膜病变(DR)是导致工作年龄成年人可预防性失明的主要原因,它会带来毁灭性的个人和社会经济后果。在过去的十年中,抗血管内皮生长因子(anti- VEGF)药物的使用越来越多,以及远程医疗在系统DR筛查中的实施,导致一些国家因糖尿病导致的新失明呈下降趋势。远程医疗是通过电信基础设施远程提供医疗保健服务。它允许医疗保健提供者评估、诊断和治疗患者,而无需亲自访问。远眼医学是远程医疗的一个分支,主要针对糖尿病视网膜病变和早产儿视网膜病变。在克罗地亚,DR筛查通常每年进行一次,仅由眼科医生使用扩张型裂隙灯生物显微眼底检查。由于眼科医生数量不足和缺乏正式的呼叫系统,许多糖尿病患者不进行年度筛查。在克罗地亚理想的DR筛查模式中,克罗地亚各地大学或综合医院的每个糖尿病中心(17个中心)将配备一台小型数字眼底相机和一名受过教育的护士进行眼底扩张摄影。来自糖尿病中心的电子图像将被转移到同一家医院的眼科或克罗地亚DR筛查的中央分级中心进行远程分级。DR的分级将由眼科医生,医学视网膜专家进行。国家糖尿病登记处每年都会通过邮件邀请患者到最近的糖尿病中心进行眼底摄影和DR筛查。每一个阳性结果的病人将被立即转介到最近的眼科医学视网膜专家进行进一步的检查和治疗。
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引用次数: 0
Knowledge on Pre-Hospital Emergency Management of Tooth Avulsion among Croatian Kindergarten Teachers 克罗地亚幼儿园教师牙齿撕脱的院前急救处理知识
Q3 Arts and Humanities Pub Date : 2020-10-01 DOI: 10.5671/ca.44.3.4
Z. Uzarevic, M. Matijević, N. Matijevic, Vedrana Nikolašević, Vesnica Mlinarević, T. Velki, Zrinka Ivanišević
The aim of this study was to evaluate knowledge on pre-hospital emergency management of tooth avulsion among Croatian kindergarten teachers. A cross-sectional study was conducted among 33 educators in kindergarten (average 43.9±9.7 years). The questionnaire contained 10 close-ended questions with two or eleven possible answers. Statistical significance was determined using chi-square test. Majority of participants had no experience with tooth injury among children in kindergarten. Questions about the familiarity with the terms of a knocked-out tooth and tooth replantation and whether the knocked-out tooth should be replanted were confirmatively answered by 90.9%, 57.6% and 63.6% of participants, respectively. Only 9.1% of participants provided the correct answer that replantation should be done within 30 minutes. 78.8% of participants would choose correct medium for cleaning if avulsed tooth got dirty. Tooth would be transported in appropriate medium by 48.5% of participants. Correct answers on both the transport medium and the cleaning of knocked-out tooth were provided by 45.5% participants. 57.6% participants would seek help for replantation by visiting the nearest dentist. None of the participants had ever received any kind of information on management of a knocked-out tooth. The kindergarten teachers have a lack of knowledge for immediate response to tooth avulsion. Every kindergarten teacher should be well informed what should be done if some type of dental injury happens. The official communication between dental professionals and kindergarten teachers should be improved at local and regional level.
本研究的目的是评估克罗地亚幼儿园教师对牙齿撕脱伤院前急救的认识。对33名幼儿园教育工作者(平均43.9±9.7岁)进行了横断面研究。问卷包含10个封闭式问题,其中有两个或十一个可能的答案。采用卡方检验确定统计学显著性。大多数参与者在幼儿园儿童中没有牙齿损伤的经历。90.9%、57.6%和63.6%的参与者分别回答了关于熟悉被打掉的牙齿和牙齿再植的术语以及是否应该再植被打掉牙齿的问题。只有9.1%的参与者给出了正确答案,即应在30分钟内完成再植。78.8%的参与者会选择正确的清洁介质,如果撕脱的牙齿变脏。48.5%的参与者会在适当的介质中运输牙齿。45.5%的参与者对传输介质和牙齿脱落的清洁都给出了正确的答案。57.6%的参与者会去最近的牙医那里寻求再植的帮助。没有一名参与者收到过任何关于牙齿脱落管理的信息。幼儿园教师缺乏对牙齿撕脱的即时反应的知识。如果发生某种类型的牙齿损伤,每个幼儿园老师都应该被告知该怎么办。牙科专业人员和幼儿园教师之间的官方沟通应在地方和地区层面得到改善。
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引用次数: 0
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Collegium Antropologicum
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