{"title":"Medalla europea «Eguzkilore 2011» de la Sociedad Vasca de Hipertensión Arterial y Riesgo Cardiovascular","authors":"Gregorio Mediavilla-Tris, Jesús Iturralde-Iriso, Julen Ocharan-Corcuera","doi":"10.1016/j.gmb.2011.07.001","DOIUrl":"10.1016/j.gmb.2011.07.001","url":null,"abstract":"","PeriodicalId":35686,"journal":{"name":"Gaceta Medica de Bilbao","volume":"108 3","pages":"Pages 96-97"},"PeriodicalIF":0.0,"publicationDate":"2011-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.gmb.2011.07.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"106027791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-04-01DOI: 10.1016/j.gmb.2011.03.003
Ana Moreno Rodrigo , Alfonso Gutiérrez Macías , Idoia Madariaga Ordeñana , María Victoria Bárcena Robredo , Eva Lizarralde Palacios , Felipe Miguel De La Villa
Perihepatitis associated with pelvic inflammatory disease or Fitz-Hugh-Curtis syndrome is an inflammatory process that involves the liver capsule and adjacent peritoneum and is related to pelvic infections due to Chlamydia trachomatis and Neisseria gonorrhoeae. Diagnosis may be difficult because the clinical picture is nonspecific, especially when manifestations of pelvic inflammatory disease are scarce or absent. In the last few years, computed tomography has been shown to be a highly useful and non-invasive diagnostic procedure in the proper clinical context. We present two cases of perihepatitis associated with pelvic inflammatory disease, diagnosed with computed tomography.
{"title":"Perihepatitis asociada a enfermedad pélvica inflamatoria (síndrome de Fitz-Hugh-Curtis). Utilidad diagnóstica de la tomografía computarizada","authors":"Ana Moreno Rodrigo , Alfonso Gutiérrez Macías , Idoia Madariaga Ordeñana , María Victoria Bárcena Robredo , Eva Lizarralde Palacios , Felipe Miguel De La Villa","doi":"10.1016/j.gmb.2011.03.003","DOIUrl":"https://doi.org/10.1016/j.gmb.2011.03.003","url":null,"abstract":"<div><p>Perihepatitis associated with pelvic inflammatory disease or Fitz-Hugh-Curtis syndrome is an inflammatory process that involves the liver capsule and adjacent peritoneum and is related to pelvic infections due to <em>Chlamydia trachomatis</em> and <em>Neisseria gonorrhoeae</em>. Diagnosis may be difficult because the clinical picture is nonspecific, especially when manifestations of pelvic inflammatory disease are scarce or absent. In the last few years, computed tomography has been shown to be a highly useful and non-invasive diagnostic procedure in the proper clinical context. We present two cases of perihepatitis associated with pelvic inflammatory disease, diagnosed with computed tomography.</p></div>","PeriodicalId":35686,"journal":{"name":"Gaceta Medica de Bilbao","volume":"108 2","pages":"Pages 49-51"},"PeriodicalIF":0.0,"publicationDate":"2011-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.gmb.2011.03.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91664063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-04-01DOI: 10.1016/j.gmb.2011.03.001
Ricardo Franco-Vicario
{"title":"Premios Dr. José Carrasco/D. Máximo de Aguirre 2011 (5a edición)","authors":"Ricardo Franco-Vicario","doi":"10.1016/j.gmb.2011.03.001","DOIUrl":"10.1016/j.gmb.2011.03.001","url":null,"abstract":"","PeriodicalId":35686,"journal":{"name":"Gaceta Medica de Bilbao","volume":"108 2","pages":"Pages 37-39"},"PeriodicalIF":0.0,"publicationDate":"2011-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.gmb.2011.03.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"105183018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-04-01DOI: 10.1016/j.gmb.2010.11.001
Ángel Cosme , Evelia Ojeda , Luis Bujanda , María Dolores De Juan , José María Alustiza , Agustín Castiella , Eva Zapata , Alejandra Gómez
Introduction
Hereditary hemochromatosis (HH) type I is due to mutations in the HFE gene, located on chromosome 6 (6p21.3). This disease is characterized by increased intestinal iron absorption and progressive storage in the liver, skin, pancreas, bones, heart and endocrine organs. Patient prognosis depends on early diagnosis and prompt treatment of the disease.
Patients and methods
We reviewed the medical records of family members (eight men and five women) with HH type I, studied and followed-up between 1985 and 2008 in Hospital Donostia, San Sebastian (Spain). Molecular studies were performed of the HFE gene and of iron overload parameters in all the family members (N = 17) belonging to two generations. In family members with the C282Y/H63D mutation and incomplete phenotype, liver iron quantification and monitoring was done by magnetic resonance imaging (MRI).
Results
The homozygous C282Y mutation was present in three family members, the heterozygous mutation (associated with H63D) in three, and the heterozygous mutation alone in six. Liver biopsy revealed fibrosis and / or cirrhosis in four family members (three with C282Y/C282Y and another with C282Y/-) aged over 40 years with hepatomegaly, arthralgia, and in some cases, skin pigmentation, fatigue, and hypogonadism. Liver MRI in two family members with the heterozygous mutation (C282Y/H63D) and transferrin saturation greater than 50% showed no iron overload after several years of monitoring, avoiding the need for phlebotomy.
Conclusions
We present the clinical manifestations of HH type 1 in this family and the molecular alterations found. Liver MRI should be incorporated into the monitoring of individuals with impaired iron metabolism and HFE gene mutations.
遗传性血色素沉着症(HH) I型是由于位于6号染色体(6p21.3)的HFE基因突变引起的。这种疾病的特点是肠道铁吸收增加，并逐渐在肝脏、皮肤、胰腺、骨骼、心脏和内分泌器官中储存。患者预后取决于疾病的早期诊断和及时治疗。患者和方法我们回顾了1985年至2008年在西班牙圣塞巴斯蒂安多诺斯蒂亚医院(Donostia, San Sebastian)研究和随访的HH I型家庭成员(8男5女)的医疗记录。我们对所有两代家族成员(N = 17)的HFE基因和铁过载参数进行了分子研究。在C282Y/H63D突变且表型不完全的家族成员中，通过磁共振成像(MRI)进行肝铁定量和监测。结果C282Y纯合突变3例，与H63D相关的杂合突变3例，单独杂合突变6例。肝活检显示，4名年龄超过40岁的家族成员(3名患有C282Y/C282Y, 1名患有C282Y/-)出现纤维化和/或肝硬化，伴有肝肿大、关节痛，部分病例伴有皮肤色素沉着、疲劳和性腺功能减退。两名杂合突变(C282Y/H63D)且转铁蛋白饱和度大于50%的家族成员，经过数年的监测，肝脏MRI显示未出现铁超载，避免了放血的需要。结论总结了该家族HH 1型的临床表现及分子改变。肝脏MRI应纳入监测铁代谢受损和HFE基因突变的个体。
{"title":"Características clínicas y evolutivas de una familia con hemocromatosis hereditaria tipo 1","authors":"Ángel Cosme , Evelia Ojeda , Luis Bujanda , María Dolores De Juan , José María Alustiza , Agustín Castiella , Eva Zapata , Alejandra Gómez","doi":"10.1016/j.gmb.2010.11.001","DOIUrl":"https://doi.org/10.1016/j.gmb.2010.11.001","url":null,"abstract":"<div><h3>Introduction</h3><p>Hereditary hemochromatosis (HH) type I is due to mutations in the <em>HFE</em> gene, located on chromosome 6 (6p21.3). This disease is characterized by increased intestinal iron absorption and progressive storage in the liver, skin, pancreas, bones, heart and endocrine organs. Patient prognosis depends on early diagnosis and prompt treatment of the disease.</p></div><div><h3>Patients and methods</h3><p>We reviewed the medical records of family members (eight men and five women) with HH type I, studied and followed-up between 1985 and 2008 in Hospital Donostia, San Sebastian (Spain). Molecular studies were performed of the <em>HFE</em> gene and of iron overload parameters in all the family members (N<!--> <!-->=<!--> <!-->17) belonging to two generations. In family members with the C282Y/H63D mutation and incomplete phenotype, liver iron quantification and monitoring was done by magnetic resonance imaging (MRI).</p></div><div><h3>Results</h3><p>The homozygous C282Y mutation was present in three family members, the heterozygous mutation (associated with H63D) in three, and the heterozygous mutation alone in six. Liver biopsy revealed fibrosis and / or cirrhosis in four family members (three with C282Y/C282Y and another with C282Y/-) aged over 40<!--> <!-->years with hepatomegaly, arthralgia, and in some cases, skin pigmentation, fatigue, and hypogonadism. Liver MRI in two family members with the heterozygous mutation (C282Y/H63D) and transferrin saturation greater than 50% showed no iron overload after several years of monitoring, avoiding the need for phlebotomy.</p></div><div><h3>Conclusions</h3><p>We present the clinical manifestations of HH type 1 in this family and the molecular alterations found. Liver MRI should be incorporated into the monitoring of individuals with impaired iron metabolism and <em>HFE</em> gene mutations.</p></div>","PeriodicalId":35686,"journal":{"name":"Gaceta Medica de Bilbao","volume":"108 2","pages":"Pages 42-48"},"PeriodicalIF":0.0,"publicationDate":"2011-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.gmb.2010.11.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91664062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-04-01DOI: 10.1016/j.gmb.2011.03.002
Mireia de la Peña Trigueros, Alfonso Gutiérrez Macías, Rafael Estrada Vicente, Felipe Miguel de la Villa
{"title":"Utilidad del octreótido long-acting release en el sangrado digestivo de origen oscuro","authors":"Mireia de la Peña Trigueros, Alfonso Gutiérrez Macías, Rafael Estrada Vicente, Felipe Miguel de la Villa","doi":"10.1016/j.gmb.2011.03.002","DOIUrl":"https://doi.org/10.1016/j.gmb.2011.03.002","url":null,"abstract":"","PeriodicalId":35686,"journal":{"name":"Gaceta Medica de Bilbao","volume":"108 2","pages":"Pages 57-59"},"PeriodicalIF":0.0,"publicationDate":"2011-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.gmb.2011.03.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91664064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-04-01DOI: 10.1016/j.gmb.2011.04.001
Julian Aguirrezabal Iñarritu
{"title":"Presentación de la XXXIII Reunión de la Sociedad Española de Odontopediatría","authors":"Julian Aguirrezabal Iñarritu","doi":"10.1016/j.gmb.2011.04.001","DOIUrl":"https://doi.org/10.1016/j.gmb.2011.04.001","url":null,"abstract":"","PeriodicalId":35686,"journal":{"name":"Gaceta Medica de Bilbao","volume":"108 2","pages":"Pages 40-41"},"PeriodicalIF":0.0,"publicationDate":"2011-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.gmb.2011.04.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91664046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-04-01DOI: 10.1016/j.gmb.2011.04.002
José Undabeitia , Juan Jesús Aurrecoechea , Maria Luisa Jáuregui , Nora Cívicos , Lara Galbarriatu , Edurne Ruiz De Gopegui , Ianire Hernández , Gregorio Catalán , Gaizka Bilbao , Guillermo Carbayo , Iñigo Pomposo
We report the case of a 77-year-old woman who was admitted to our hospital with cauda equina syndrome. An urgent magnetic resonance imaging scan showed lumbar spinal canal compression at L4-L5 and L5-S1. An urgent laminectomy was performed and cystic lesions were extracted. On pathological examination, the lesions were identified as synovial cysts. The patient required rehabilitation and achieved good functional recovery, although sensory deficit remains in the sacral segments.
{"title":"Quiste sinovial lumbar como causa de síndrome de cauda equina. Presentación de un caso y revisión de la literatura","authors":"José Undabeitia , Juan Jesús Aurrecoechea , Maria Luisa Jáuregui , Nora Cívicos , Lara Galbarriatu , Edurne Ruiz De Gopegui , Ianire Hernández , Gregorio Catalán , Gaizka Bilbao , Guillermo Carbayo , Iñigo Pomposo","doi":"10.1016/j.gmb.2011.04.002","DOIUrl":"https://doi.org/10.1016/j.gmb.2011.04.002","url":null,"abstract":"<div><p>We report the case of a 77-year-old woman who was admitted to our hospital with cauda equina syndrome. An urgent magnetic resonance imaging scan showed lumbar spinal canal compression at L4-L5 and L5-S1. An urgent laminectomy was performed and cystic lesions were extracted. On pathological examination, the lesions were identified as synovial cysts. The patient required rehabilitation and achieved good functional recovery, although sensory deficit remains in the sacral segments.</p></div>","PeriodicalId":35686,"journal":{"name":"Gaceta Medica de Bilbao","volume":"108 2","pages":"Pages 52-56"},"PeriodicalIF":0.0,"publicationDate":"2011-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.gmb.2011.04.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90011023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-01-01DOI: 10.1016/j.gmb.2011.02.008
Guillermo Quindós
{"title":"In memoriam a José Pontón","authors":"Guillermo Quindós","doi":"10.1016/j.gmb.2011.02.008","DOIUrl":"https://doi.org/10.1016/j.gmb.2011.02.008","url":null,"abstract":"","PeriodicalId":35686,"journal":{"name":"Gaceta Medica de Bilbao","volume":"108 1","pages":"Pages 30-32"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.gmb.2011.02.008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137332185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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