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Estudio de la actividad antibacteriana en un hospital terciario. Evolución durante el período 2000-2005 某三级医院抗菌活性研究。2000-2005年期间的演变
Q4 Medicine Pub Date : 2011-01-01 DOI: 10.1016/j.gmb.2011.02.001
A. Alberte Castiñeiras , Ángel San Miguel Hernández , M.J. Rodríguez Barbero , C. Alberte Pérez , P. Pérez Pascual

Knowledge of the antibiotic resistance in a specific healthcare area is essential for suitable application of the antibiotic policy, which can be understood as the use of recommendations for the application and consumption of antimicrobial agents, as well as for education and continual surveillance to achieve the most effective, rational and least expensive antibiotic therapy possible.

We performed a study of antimicrobial susceptibility between 2000 and 2005 in the Health Area of the West of Valladolid (Spain) corresponding to the Rio Hortega University Hospital, with a catchment area of approximately 235,0000 inhabitants.

The microorganisms tested were obtained from isolates of distinct samples from patients with infectious processes. The agents were considered causal. The most frequently isolated agents were described.

The antibiotics tested were those that showed acceptable in vitro and in vivo activity against each isolated species. The criteria considered were clinical effectiveness, the prevalence of resistance, a low possibility of developing resistance, indications for clinical use and being the first treatment choice or alternative. The results were expressed in percentages of susceptibility or sensitivity to the antibiotics analyzed.

The sensitivity criteria of the National Committee on Clinical Laboratory Standards (USA) were followed. The category of SENSITIVE to a given antibiotic implies that the infection caused by the isolated bacterium can suitably be treated with the routine dosage of this antibiotic. The RESISTANT category implies that isolated bacteria are not inhibited with the routine dosage of this antibiotic.

The antibiotic types studied followed general lines and the following agents were taken as representative of their class: Ampicillin (ampicillin and amoxicillin derivatives), Amoxicillin/clavulanic acid(ampicillin/sulbactam), Cefalotin (cefazolin, cefaclor, cephradine, cefalexin, etc), Cefoxitin (cefmetazole), Cefotaxime (ceftriaxone, imipenem, meropenem), Gentamicin (netilmicin, tobramycin), Ciprofloxacin (ofloxacin), Ofloxacin (levofloxacin). In Enterococci: Gentamicin synergy (gentamicin, tobramycin, netilmicin and amikacin). Streptomycin synergy (streptomycin).

The results obtained in the study were grouped in different antibiotic activities:

  • 1.

    Antibiotic activity against Gram-positive bacteria: a. Antibiotic activity against to Staphylococcus aureus. b. Antibiotic activity against S epidermidis. c. Antibiotic activity against Enterococcus faecalis d. Antibiotic activity against E. faecium. e. Antibiotic activity against Streptococcus agalactiae.

  • 2.

    Antibiotic activity against Gram-negative bacteria. a. Antibiotic activity against Enterobacteriaceae. Antibiotic activity against Escherichia coli. Antibiotic activity against

了解特定卫生保健领域的抗生素耐药性对于适当实施抗生素政策至关重要,这可以理解为使用抗菌剂的应用和消费建议,以及教育和持续监测,以实现最有效、合理和最便宜的抗生素治疗。我们在2000年至2005年期间对巴利亚多利德西部卫生区(西班牙)的抗微生物药物敏感性进行了一项研究,该地区与里约奥尔特加大学医院相对应,集水区约有23.5万居民。所测试的微生物是从感染过程患者的不同样本分离物中获得的。这些因素被认为是因果关系。描述了最常被分离的药剂。测试的抗生素是那些在体外和体内对每个分离物种都显示出可接受的活性的抗生素。考虑的标准是临床有效性、耐药发生率、发生耐药的可能性低、临床使用的适应症以及作为第一治疗选择或替代方案。结果以对所分析抗生素的敏感性百分比表示。按照美国国家临床实验室标准委员会的敏感性标准。对某一抗生素敏感的类别意味着由分离的细菌引起的感染可以适当地用这种抗生素的常规剂量治疗。耐药类别意味着这种抗生素的常规剂量不能抑制分离的细菌。所研究的抗生素种类遵循一般路线,以下列药物为代表:氨苄西林(氨苄西林及阿莫西林衍生物)、阿莫西林/克拉维酸(氨苄西林/舒巴坦)、头孢丁(头孢唑林、头孢克洛、头孢定、头孢氨苄等)、头孢西丁(头孢美唑)、头孢噻肟(头孢曲松、亚胺培南、美罗培南)、庆大霉素(奈替米星、妥布霉素)、环丙沙星(氧氟沙星)、氧氟沙星(左氧氟沙星)。肠球菌:庆大霉素协同作用(庆大霉素、妥布霉素、奈替霉素和阿米卡星)。链霉素协同(链霉素)。本研究得到的结果按不同的抗生素活性进行分组:对革兰氏阳性细菌的抗生素活性:a.对金黄色葡萄球菌的抗生素活性。b.对表皮葡萄球菌的抗生素活性。c.对粪肠球菌的抗生素活性d.对粪肠球菌的抗生素活性e.对无乳链球菌的抗生素活性。抗革兰氏阴性菌的抗生素活性。a.对肠杆菌科的抗生素活性。对大肠杆菌的抗生素活性。对肺炎克雷伯菌和产氧克雷伯菌的抗生素活性。对阴沟肠杆菌的抗生素活性。对粘质沙雷氏菌的抗生素活性。对奇异变形杆菌的抗生素活性。2 .对摩根氏菌的抗菌活性。对非发酵革兰氏阴性杆菌(NFGNB)的抗菌活性。对铜绿假单胞菌的抗菌活性。鲍曼不动杆菌的抗菌活性。对嗜麦芽寡养单胞菌的抗菌活性。对各种微生物的抗生素活性。a.抗卡他氏布氏菌的抗生素活性。b.抗流感嗜血杆菌的抗生素活性。因此,尽管存在许多耐抗生素细菌,但仍有一些菌株经常引起感染,无法用普通抗生素治疗。因此,应改变常规的治疗方案。这些细菌通常毒性特别强,会引起严重的感染。
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引用次数: 0
Q4 Medicine Pub Date : 2011-01-01 DOI: 10.1016/j.gmb.2011.02.002
Pedro Gorrotxategi Gorrotxategi
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引用次数: 0
Q4 Medicine Pub Date : 2011-01-01 DOI: 10.1016/j.gmb.2011.02.003
Ricardo Franco Vicario
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引用次数: 0
El gasto sanitario público en el País Vasco, 1995-2008: comparación con el conjunto de las comunidades autónomas 1995-2008年巴斯克地区的公共卫生支出:与所有自治社区的比较
Q4 Medicine Pub Date : 2011-01-01 DOI: 10.1016/j.gmb.2011.02.006
Juan Simó Miñana

Objective

To determine the growth and distribution of public expenditure on health among health sectors in the Basque Country from 1995 to 2008 and compare them with those in the 17 autonomous regions in Spain as a whole.

Method

Public expenditure on health in the Basque Country among health sectors and its annual growth were determined and compared with average expenditure in Spain's 17 autonomous regions through a retrospective longitudinal study. Demographic variables such as regional income (GDP per capita) and population aging were also analyzed.

Results

Between 2002 and 2008, the per capita public expenditure on health in the Basque Country was 10% higher than the average in the autonomous regions and growth was 1.3% higher. Per capita pharmaceutical expenditure in the Basque Country was 2% lower than the regional average, growth was 27% higher than this average, and its weight in public expenditure on health grew 0.950% annually. The annual growth of hospital expenditure in the Basque Country was 15% higher than that in primary care (3.571% vs. 3.097%) and the weight of primary care in public expenditure on health decreased 2.6 times more than that of hospital care. On average during the period, both sectors exceeded the regional average of per capita expenditure by 16-17%. However, per capita expenditure on hospital staff in the Basque Country was 20-30% higher than the regional average while that on primary care staff was 10-15% higher than this average.

Conclusions

Between 1995 and 2008, Basque hospital and primary care maintained their budgetary superiority over the regional average. In hospital staff, this budgetary superiority was double that in primary care compared with the regional average. Pharmaceutical expenditure was within the regional average.

目的确定1995年至2008年巴斯克地区卫生部门公共卫生支出的增长和分布情况,并将其与西班牙17个自治区的情况进行比较。方法通过回顾性纵向研究,确定巴斯克地区卫生部门的公共卫生支出及其年增长率,并与西班牙17个自治区的平均支出进行比较。人口统计变量如地区收入(人均GDP)和人口老龄化也进行了分析。结果2002 - 2008年,巴斯克地区人均卫生公共支出比自治区平均水平高10%,增长率比自治区平均水平高1.3%。巴斯克地区的人均药品支出比区域平均水平低2%,增长率比该平均水平高27%,其在公共卫生支出中的权重每年增长0.950%。巴斯克地区医院支出的年增长率比初级保健高15%(3.571%比3.097%),初级保健在公共卫生支出中的权重下降幅度是医院保健的2.6倍。在此期间,这两个部门的人均支出平均超过区域平均水平16-17%。然而,巴斯克地区医院工作人员的人均支出比地区平均水平高出20-30%,而初级保健工作人员的人均支出比地区平均水平高出10-15%。结论1995年至2008年间,巴斯克地区医院和初级保健机构的预算优势高于地区平均水平。在医院工作人员中,与地区平均水平相比,这种预算优势是初级保健的两倍。药品支出在区域平均水平之内。
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引用次数: 0
Morir en casa con dignidad. Una posibilidad, si hay apoyo y cuidados de calidad 在家里有尊严地死去。如果有高质量的支持和护理,这是一种可能性
Q4 Medicine Pub Date : 2011-01-01 DOI: 10.1016/j.gmb.2011.02.004
Juan Gérvas
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引用次数: 6
Discurso leído en la entrega del Premio Ilustre de Bilbao a la Academia 在向学院颁发毕尔巴鄂杰出奖时宣读的讲话
Q4 Medicine Pub Date : 2011-01-01 DOI: 10.1016/j.gmb.2011.02.007
Juan Goiria
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引用次数: 0
Medalla Europea “Eguzkilore 2009” de la Sociedad Vasca de Hipertensión Arterial y Riesgo Cardiovascular 巴斯克高血压和心血管风险学会“Eguzkilore 2009”欧洲奖章
Q4 Medicine Pub Date : 2010-10-01 DOI: 10.1016/S0304-4858(10)70034-2
Julen Ocharan-Corcuera, Jesús Iturralde-Iriso, Gregorio Mediavilla-Tris
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引用次数: 0
Priapismo: concepciones clínicas, diagnósticas y de tratamiento 阴茎勃起:临床、诊断和治疗概念
Q4 Medicine Pub Date : 2010-10-01 DOI: 10.1016/S0304-4858(10)70033-0
Jon Kepa Balparda-Arias

Priapism is defined as a clinical entity in which there's a sustained penile erection, not related to any sort of sexual stimulation. It may represent a true urologic emergency, taking into account that the low flow variant has been strongly related to permanent sexual dysfunction. Treatment will depend on whether the disease is of the ischemic or the non ischemic variant, with the therapeutics of the first including cavernosal aspiration, intracavernosal injection with constrictive agents and surgical management.

Laburpena

Priapismoa, hain zuzen, sexu-kitzikapenarekin loturarik ez duen zakilaren erekzio iraunkorra da. Urologia-arazo larria izan daiteke; izan ere, Fluxu Baxua izeneko aldagaiak zuzeneko harremana dauka sexu-disfuntzio iraunkorrarekin. Tratamendu egokia zein den erabakitzeko, oro har, aldagai iskemikoa eta ez-iskemikoa bereizi behar dira. Lehenengoari aurre egiteko tratamendua, beraz, leizeetako xurgapenean, sendagai basokontriktoreen instilazioan eta kirurgia-terapeutikan oinarritutakoa izan liteke.

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引用次数: 2
Tratamiento percutáneo del osteoma osteoide mediante ablación por radiofrecuencia guiada por TC, en niños y adolescentes ct引导射频消融经皮治疗儿童和青少年类骨瘤
Q4 Medicine Pub Date : 2010-10-01 DOI: 10.1016/S0304-4858(10)70031-7
Serafín García Mata

Computed tomography-guided radiofrequency ablation was performed under general anesthesia and in outpatient surgery. Symptoms resolved within 0–5 days. Pain resolved in all patients without complications. There were no recurrences during a follow-up of between 9 months and 3 years. No physeal involvement was observed, even when the lesion was close to the physis.

在全身麻醉和门诊手术中进行计算机断层扫描引导射频消融。症状在0-5天内解决。所有患者疼痛缓解,无并发症。随访9个月至3年无复发。没有观察到物理受累,即使当病变靠近物理。
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引用次数: 2
In memoriam al Prof. Dr. José María Rivera-Pomar 纪念约瑟夫博士María里维拉-波马尔教授
Q4 Medicine Pub Date : 2010-10-01 DOI: 10.1016/S0304-4858(10)70038-X
Carmen de la Hoz Torres
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引用次数: 0
期刊
Gaceta Medica de Bilbao
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