Pub Date : 2022-06-30DOI: 10.17966/jmi.2022.27.2.38
Ju Yeong Lee, E. Choi
{"title":"Skin Infection Caused by Mycobacterium abscessus in a\u0000Healthy Adult","authors":"Ju Yeong Lee, E. Choi","doi":"10.17966/jmi.2022.27.2.38","DOIUrl":"https://doi.org/10.17966/jmi.2022.27.2.38","url":null,"abstract":"","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45558206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-30DOI: 10.17966/jmi.2022.27.2.43
W. Jin, S. Hong, Seung Hee Jang, Hyojin Kim
{"title":"Pigmentary Changes on Facial Mask-covered Area:\u0000is it Related to Alteration of Microenvironment\u0000in the Era of COVID-19?","authors":"W. Jin, S. Hong, Seung Hee Jang, Hyojin Kim","doi":"10.17966/jmi.2022.27.2.43","DOIUrl":"https://doi.org/10.17966/jmi.2022.27.2.43","url":null,"abstract":"","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43007157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-30DOI: 10.17966/jmi.2022.27.2.25
Lee Jungsoo, J. Yun, Sung-Min Park, Kihyuk Shin, Hoonsoo Kim, Byung-Soo Kim, M. Kim, H. Ko
Background: Dermatologic diseases are generally managed at an outpatient clinic and most cases have very low mortality rates. However, some dermatologic diseases are life-threatening and only a few studies have assessed their mortality rates and associated factors. Objective: To investigate the mortality of inpatients with dermatological diseases. Methods: This retrospective study was conducted by reviewing the medical records of patients who died in the dermatology ward at a tertiary hospital in Korea in a period of 17 years. Patient demographics, dermatologic diseases, immediate cause of death, comorbidities, and clinical factors related with mortality were investigated. Results: The total number of inpatients in the dermatology ward during the study period was 740. Thirteen patients (1.76%, 5 men and 8 women) expired while they were admitted in the hospital. The median age of the patients was 63.8 years (range, 18 to 86), and the maximum number of deaths occurred in patients over 70 years old (7 out of 13 patients, 53.8%). Drug reactions were the most common dermatologic complication resulting in admission, followed by bullous disease, generalized pustular psoriasis, and dermatomyositis. Most patients had multiple comorbidities, including hypertension, diabetes mellitus, kidney disease, and angina. Sepsis due to infection was the most common cause of death. Conclusion: Infection was the most important factor contributing to mortality. Old age, immunosuppression, and comorbidities were important factors that contributed to mortality in dermatologic inpatients.
{"title":"Assessment of Mortality among Inpatient Cases with\u0000Severe Dermatologic Diseases: Infection and Sepsis,\u0000the Most Common cause of Mortality","authors":"Lee Jungsoo, J. Yun, Sung-Min Park, Kihyuk Shin, Hoonsoo Kim, Byung-Soo Kim, M. Kim, H. Ko","doi":"10.17966/jmi.2022.27.2.25","DOIUrl":"https://doi.org/10.17966/jmi.2022.27.2.25","url":null,"abstract":"Background: Dermatologic diseases are generally managed at an outpatient clinic and most cases have very low\u0000mortality rates. However, some dermatologic diseases are life-threatening and only a few studies have assessed\u0000their mortality rates and associated factors.\u0000Objective: To investigate the mortality of inpatients with dermatological diseases.\u0000Methods: This retrospective study was conducted by reviewing the medical records of patients who died in the\u0000dermatology ward at a tertiary hospital in Korea in a period of 17 years. Patient demographics, dermatologic\u0000diseases, immediate cause of death, comorbidities, and clinical factors related with mortality were investigated.\u0000Results: The total number of inpatients in the dermatology ward during the study period was 740. Thirteen\u0000patients (1.76%, 5 men and 8 women) expired while they were admitted in the hospital. The median age of the\u0000patients was 63.8 years (range, 18 to 86), and the maximum number of deaths occurred in patients over 70 years\u0000old (7 out of 13 patients, 53.8%). Drug reactions were the most common dermatologic complication resulting in\u0000admission, followed by bullous disease, generalized pustular psoriasis, and dermatomyositis. Most patients had\u0000multiple comorbidities, including hypertension, diabetes mellitus, kidney disease, and angina. Sepsis due to infection\u0000was the most common cause of death.\u0000Conclusion: Infection was the most important factor contributing to mortality. Old age, immunosuppression, and\u0000comorbidities were important factors that contributed to mortality in dermatologic inpatients.","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45499991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-30DOI: 10.17966/jmi.2022.27.2.32
Jungsoon Lee, J. Yun, Kihyuk Shin, H. Ko, Byungsoo Kim, M. Kim, Hoonsoo Kim
Ungual melanoma is known to be frequently misdiagnosed, and the primary misdiagnosis of ungual melanoma includes onychomycosis. We report a very rare case of onychomycosis concealing ungual melanoma in situ. A 52- year-old male patient presented with a yellow to brown thickened left great toenail that had existed for 10 years. In the front view, Hutchinson's sign which refers periungual extension of brown-black pigmentation from melanonychia was also observed on his hyponychium. First, fungal infection of his toenail was confirmed with positive KOH result. Next, a nail biopsy after nail avulsion was done to assess Breslow depth and to determine surgical margin. And ungual melanoma was diagnosed with immunohistochemical stains. Non-amputative wide local excision with 5 mm surgical margin followed by skin grafting was done Unfortunately in three years ungual melanoma in situ has recurred 2 times and then progressed to invasive malignant melanoma, so he was referred to the Department of plastic surgery for further invasive surgical treatment and regularly monitored to check the recurrence. According to a prior retrospective study, 52% of ungual melanomas were clinically misdiagnosed. Thus, proper diagnosis of ungual melanoma is very important for the patients' better prognosis. It would be important for physicians to examine the nail plate as well as the underneath structures for patients with nail disease including onychomycosis.
{"title":"Ungual Melanoma Disguised by Onychomycosis","authors":"Jungsoon Lee, J. Yun, Kihyuk Shin, H. Ko, Byungsoo Kim, M. Kim, Hoonsoo Kim","doi":"10.17966/jmi.2022.27.2.32","DOIUrl":"https://doi.org/10.17966/jmi.2022.27.2.32","url":null,"abstract":"Ungual melanoma is known to be frequently misdiagnosed, and the primary misdiagnosis of ungual melanoma\u0000includes onychomycosis. We report a very rare case of onychomycosis concealing ungual melanoma in situ. A 52-\u0000year-old male patient presented with a yellow to brown thickened left great toenail that had existed for 10 years. In\u0000the front view, Hutchinson's sign which refers periungual extension of brown-black pigmentation from melanonychia\u0000was also observed on his hyponychium. First, fungal infection of his toenail was confirmed with positive KOH\u0000result. Next, a nail biopsy after nail avulsion was done to assess Breslow depth and to determine surgical margin.\u0000And ungual melanoma was diagnosed with immunohistochemical stains. Non-amputative wide local excision with\u00005 mm surgical margin followed by skin grafting was done Unfortunately in three years ungual melanoma in situ\u0000has recurred 2 times and then progressed to invasive malignant melanoma, so he was referred to the Department\u0000of plastic surgery for further invasive surgical treatment and regularly monitored to check the recurrence. According\u0000to a prior retrospective study, 52% of ungual melanomas were clinically misdiagnosed. Thus, proper diagnosis of\u0000ungual melanoma is very important for the patients' better prognosis. It would be important for physicians to\u0000examine the nail plate as well as the underneath structures for patients with nail disease including onychomycosis.","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47783239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-30DOI: 10.17966/10.17966/jmi.2022.27.2.36
Hyun-Min Seo, Ki Yeon Kim, J. H. Park, S. Park, J. Kim
{"title":"Primary Syphilis Resembling Pyogenic Granuloma","authors":"Hyun-Min Seo, Ki Yeon Kim, J. H. Park, S. Park, J. Kim","doi":"10.17966/10.17966/jmi.2022.27.2.36","DOIUrl":"https://doi.org/10.17966/10.17966/jmi.2022.27.2.36","url":null,"abstract":"","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49382174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-31DOI: 10.17966/jmi.2022.27.1.1
Young-Hoon Hwang, W. Park
As the coronavirus disease 2019 (COVID-19) pandemic continues, a new disease, COVID-19-associated pulmonary aspergillosis (CAPA), is on the rise. CAPA is a secondary fungal infection in patients with critical COVID-19 receiving mechanical ventilation in intensive care units (ICUs). Although the incidence rate of CAPA is estimated to be 10.2% in ICU patients, CAPA appears to be associated with an increase in overall mortality. CAPA is like classical invasive pulmonary aspergillosis (IPA) but has an ambiguous clinical manifestation and occurs without typical host factors. It is also like influenza-associated pulmonary aspergillosis but differs in clinical characteristics. For research and clinical practice, the European Confederation for Medical Mycology and the International Society for Human and Animal Mycology proposed novel case definition criteria for CAPA. Although CAPA management is not much different from typical IPA, areas of uncertainty remain that require further investigation.
{"title":"Coronavirus Disease 2019-Associated Pulmonary\u0000Aspergillosis","authors":"Young-Hoon Hwang, W. Park","doi":"10.17966/jmi.2022.27.1.1","DOIUrl":"https://doi.org/10.17966/jmi.2022.27.1.1","url":null,"abstract":"As the coronavirus disease 2019 (COVID-19) pandemic continues, a new disease, COVID-19-associated pulmonary\u0000aspergillosis (CAPA), is on the rise. CAPA is a secondary fungal infection in patients with critical COVID-19 receiving\u0000mechanical ventilation in intensive care units (ICUs). Although the incidence rate of CAPA is estimated to be 10.2%\u0000in ICU patients, CAPA appears to be associated with an increase in overall mortality. CAPA is like classical invasive\u0000pulmonary aspergillosis (IPA) but has an ambiguous clinical manifestation and occurs without typical host factors.\u0000It is also like influenza-associated pulmonary aspergillosis but differs in clinical characteristics. For research and\u0000clinical practice, the European Confederation for Medical Mycology and the International Society for Human and\u0000Animal Mycology proposed novel case definition criteria for CAPA. Although CAPA management is not much\u0000different from typical IPA, areas of uncertainty remain that require further investigation.","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43510030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-31DOI: 10.17966/jmi.2022.27.1.9
Dong Heon Lee, H. Jung
Seborrheic dermatitis (SD) is a chronic inflammatory skin disease in which scaling and erythema occur on various body parts, such as the scalp, eyebrows, nasolabial folds, and ears. Although it is a common skin disease, its pathogenesis remains unclear. It has various causes, including microorganisms and immune and nervous system abnormalities that act in a complex manner. The skin mycobiome/microbiome, an important factor in SD occurrence, is being actively studied. Among the skin microorganisms related to SD, Malassezia and Cutibacterium have been extensively studied. Recently, it was revealed that various microorganisms are related in several ways. The study of changes in mycobiome/microbiome involves comparing types and abundances of microorganisms and degrees of microbial diversity; patients and healthy individuals; the lesion and nonlesion areas; and affected body parts. Several studies on the mycobiome/microbiome associated with SD have shown relatively consistent results; however, some have revealed different outcomes. These variations occur because of differences in individuals, study groups, and sampling/study methodology. Therefore, further research is needed for the application the results of these studies in the treatment of SD.
{"title":"Mycobiome and Microbiome in Seborrheic Dermatitis","authors":"Dong Heon Lee, H. Jung","doi":"10.17966/jmi.2022.27.1.9","DOIUrl":"https://doi.org/10.17966/jmi.2022.27.1.9","url":null,"abstract":"Seborrheic dermatitis (SD) is a chronic inflammatory skin disease in which scaling and erythema occur on various\u0000body parts, such as the scalp, eyebrows, nasolabial folds, and ears. Although it is a common skin disease, its\u0000pathogenesis remains unclear. It has various causes, including microorganisms and immune and nervous system\u0000abnormalities that act in a complex manner. The skin mycobiome/microbiome, an important factor in SD occurrence,\u0000is being actively studied. Among the skin microorganisms related to SD, Malassezia and Cutibacterium have been\u0000extensively studied. Recently, it was revealed that various microorganisms are related in several ways. The study\u0000of changes in mycobiome/microbiome involves comparing types and abundances of microorganisms and degrees\u0000of microbial diversity; patients and healthy individuals; the lesion and nonlesion areas; and affected body parts.\u0000Several studies on the mycobiome/microbiome associated with SD have shown relatively consistent results; however,\u0000some have revealed different outcomes. These variations occur because of differences in individuals, study groups,\u0000and sampling/study methodology. Therefore, further research is needed for the application the results of these\u0000studies in the treatment of SD.","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44755526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-31DOI: 10.17966/jmi.2022.27.1.21
Hyun-Min Seo, S. Park, J. H. Park, Ki Yeon Kim, J. Kim
{"title":"Scarring Alopecia After Kerion Celsi in Adults","authors":"Hyun-Min Seo, S. Park, J. H. Park, Ki Yeon Kim, J. Kim","doi":"10.17966/jmi.2022.27.1.21","DOIUrl":"https://doi.org/10.17966/jmi.2022.27.1.21","url":null,"abstract":"","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42267228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-31DOI: 10.17966/jmi.2022.27.1.19
Narang Hong, H. D. Kook, Dong Heon Lee, Jiyoung Ahn, M. Park, H. Jung
{"title":"Pilomatricoma Developed After SARS-CoV-2\u0000mRNA Vaccine Inoculation","authors":"Narang Hong, H. D. Kook, Dong Heon Lee, Jiyoung Ahn, M. Park, H. Jung","doi":"10.17966/jmi.2022.27.1.19","DOIUrl":"https://doi.org/10.17966/jmi.2022.27.1.19","url":null,"abstract":"","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47598647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-31DOI: 10.17966/jmi.2022.27.1.14
Tae-Kwon Kim, Yongwoo Choi, J. Choi, Joonsoo Park
Most superficial fungal infections of the skin are caused due to dermatophytosis or yeasts. However, it is rare for Cryptococcus species to cause infections. Among the fungal infections by Cryptotoccus species, Cryptococcus (C.) neoformans and C. gattii are the most common pathogenic species. However, other rare infections have been reported. Subcutaneous cryptococcosis due to Naganishia (N.) diffluens (formerly Cryptococcus diffluens) was first reported in Turkey. We present the case of a 53-year-old man who had mild pruritic annular, erythematous, scaly patches with inner small, crusted papules and nodules on both axilla and trunk for 3 months. A potassium hydroxide test on his abdomen scales was positive. Fungal culture, light microscopic findings, and the sequencing of an internal transcribed spacer of rRNA gene confirmed the presence of N. diffluens. As a result we diagnosed the patient with a superficial fungal infection caused by N. diffluens and treated it successfully with oral itraconazole and topical isoconazole.
{"title":"A Case of Superficial Fungal Infection caused by\u0000Naganishia diffluens","authors":"Tae-Kwon Kim, Yongwoo Choi, J. Choi, Joonsoo Park","doi":"10.17966/jmi.2022.27.1.14","DOIUrl":"https://doi.org/10.17966/jmi.2022.27.1.14","url":null,"abstract":"Most superficial fungal infections of the skin are caused due to dermatophytosis or yeasts. However, it is rare for\u0000Cryptococcus species to cause infections. Among the fungal infections by Cryptotoccus species, Cryptococcus\u0000(C.) neoformans and C. gattii are the most common pathogenic species. However, other rare infections have been\u0000reported. Subcutaneous cryptococcosis due to Naganishia (N.) diffluens (formerly Cryptococcus diffluens) was\u0000first reported in Turkey. We present the case of a 53-year-old man who had mild pruritic annular, erythematous,\u0000scaly patches with inner small, crusted papules and nodules on both axilla and trunk for 3 months. A potassium\u0000hydroxide test on his abdomen scales was positive. Fungal culture, light microscopic findings, and the sequencing\u0000of an internal transcribed spacer of rRNA gene confirmed the presence of N. diffluens. As a result we diagnosed the\u0000patient with a superficial fungal infection caused by N. diffluens and treated it successfully with oral itraconazole\u0000and topical isoconazole.","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44685776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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