Pub Date : 2022-12-31DOI: 10.17966/jmi.2022.27.4.89
H. Yang, Min Jae Kim, J. Mun
{"title":"Squamous Cell Carcinoma of the Scalp with\u0000Tinea Capitis and Bacterial Infection","authors":"H. Yang, Min Jae Kim, J. Mun","doi":"10.17966/jmi.2022.27.4.89","DOIUrl":"https://doi.org/10.17966/jmi.2022.27.4.89","url":null,"abstract":"","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47540692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-31DOI: 10.17966/jmi.2022.27.4.82
Su Min Lee, S. Yun, J. Lee
Leukonychia is the white discoloration of the nail, and it is a common chromatic abnormality of the nail. Leukonychia can be caused by various systemic conditions; however, a fungal infection is also a probable cause. Herein, we report two cases that presented with varying patterns of single-nail leukonychia and were diagnosed with fungal leukonychia based on potassium hydroxide (KOH) examination and fungal culture. A 59-year-old man presented with asymptomatic complete whitish discoloration of the right fourth fingernail. KOH examination revealed many septate hyphae, and Trichophyton rubrum was identified through fungal culture and 18S rRNA sequencing. A 32-year-old man presented with asymptomatic longitudinal ridges and pitting with partial whitish discoloration of the second left fingernail persistent for 5 years. KOH examination revealed many short hyphae, and Scedosporium species was identified on fungal culture.
{"title":"Two Cases of Single-fingernail Fungal Leukonychia with\u0000Varying Manifestations","authors":"Su Min Lee, S. Yun, J. Lee","doi":"10.17966/jmi.2022.27.4.82","DOIUrl":"https://doi.org/10.17966/jmi.2022.27.4.82","url":null,"abstract":"Leukonychia is the white discoloration of the nail, and it is a common chromatic abnormality of the nail. Leukonychia can be caused by various systemic conditions; however, a fungal infection is also a probable cause. Herein, we report two cases that presented with varying patterns of single-nail leukonychia and were diagnosed with fungal leukonychia based on potassium hydroxide (KOH) examination and fungal culture. A 59-year-old man presented with asymptomatic complete whitish discoloration of the right fourth fingernail. KOH examination revealed many septate hyphae, and Trichophyton rubrum was identified through fungal culture and 18S rRNA sequencing. A 32-year-old man presented with asymptomatic longitudinal ridges and pitting with partial whitish discoloration of the second left fingernail persistent for 5 years. KOH examination revealed many short hyphae, and Scedosporium species was identified on fungal culture.","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46379352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-31DOI: 10.17966/jmi.2022.27.4.91
Jin Seon Bang, Y. Jang
{"title":"Pemphigus Vulgaris in a Healthy Adult after\u0000COVID-19 Vaccination","authors":"Jin Seon Bang, Y. Jang","doi":"10.17966/jmi.2022.27.4.91","DOIUrl":"https://doi.org/10.17966/jmi.2022.27.4.91","url":null,"abstract":"","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49163755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-31DOI: 10.17966/jmi.2022.27.4.75
Young-Hoon Hwang, Donghwan Kim, C. K. Kang, P. G. Choe, W. Park, N. Kim, M. Oh
Background: Coronavirus disease 2019 (COVID-19)-associated pulmonary aspergillosis (CAPA) is a life-threatening invasive fungal infection in critically ill patients with COVID-19. However, only a few studies have reported CAPA in the Republic of Korea. Objective: To describe clinical characteristics of CAPA in patients at a tertiary care hospital in the Republic of Korea. Methods: This retrospective, observational consecutive case series study was conducted by reviewing the electronic medical records of patients who developed CAPA at Seoul National University Hospital from January 1, 2020, to August 31, 2021. CAPA was defined by European Confederation of Medical Mycology/International Society for Human and Animal Mycology (ECMM/ISHAM) consensus criteria. Patient demographics, comorbidities, corticosteroid use, clinical presentation, treatment, and outcomes were investigated. Results: Eleven patients were diagnosed with probable CAPA according to the ECMM/ISHAM criteria. One patient had classical host factor for invasive pulmonary aspergillosis before admission. All patients received corticosteroid therapy before CAPA diagnosis. The mean total corticosteroid administered before CAPA diagnosis was 220 mg of dexamethasone equivalent dose (range, 80~572 mg), and the mean duration of steroid therapy was 15 days (range, 4~34 days). The median time from intensive care unit admission to CAPA diagnosis was 12 days (range, 5~36 days). All individuals showed aggravation on chest X-rays. Ten patients were diagnosed with positive serum galactomannan (GM), and one was diagnosed with positive GM in a bronchoalveolar lavage specimen. Of the 11 patients, 8 received voriconazole-based antifungal therapy for a median of 30.5 days. Only two patients survived after antifungal treatment. Conclusion: These cases illustrate CAPA complicated in critically ill COVID-19 patients. The challenges in diagnosis and poor outcomes of CAPA emphasize the clinical suspicion and needs for further investigation.
{"title":"Clinical Characteristics of Patients with Probable Coronavirus Disease 2019-associated Pulmonary Aspergillosis at a Tertiary Care Hospital in the Republic of Korea: A Case Series","authors":"Young-Hoon Hwang, Donghwan Kim, C. K. Kang, P. G. Choe, W. Park, N. Kim, M. Oh","doi":"10.17966/jmi.2022.27.4.75","DOIUrl":"https://doi.org/10.17966/jmi.2022.27.4.75","url":null,"abstract":"Background: Coronavirus disease 2019 (COVID-19)-associated pulmonary aspergillosis (CAPA) is a life-threatening invasive fungal infection in critically ill patients with COVID-19. However, only a few studies have reported CAPA in the Republic of Korea.\u0000Objective: To describe clinical characteristics of CAPA in patients at a tertiary care hospital in the Republic of Korea.\u0000Methods: This retrospective, observational consecutive case series study was conducted by reviewing the electronic medical records of patients who developed CAPA at Seoul National University Hospital from January 1, 2020, to August 31, 2021. CAPA was defined by European Confederation of Medical Mycology/International Society for\u0000Human and Animal Mycology (ECMM/ISHAM) consensus criteria. Patient demographics, comorbidities, corticosteroid use, clinical presentation, treatment, and outcomes were investigated.\u0000Results: Eleven patients were diagnosed with probable CAPA according to the ECMM/ISHAM criteria. One patient had classical host factor for invasive pulmonary aspergillosis before admission. All patients received corticosteroid therapy before CAPA diagnosis. The mean total corticosteroid administered before CAPA diagnosis was 220 mg of dexamethasone equivalent dose (range, 80~572 mg), and the mean duration of steroid therapy was 15 days (range, 4~34 days). The median time from intensive care unit admission to CAPA diagnosis was 12 days (range, 5~36 days). All individuals showed aggravation on chest X-rays. Ten patients were diagnosed with positive serum\u0000galactomannan (GM), and one was diagnosed with positive GM in a bronchoalveolar lavage specimen. Of the 11 patients, 8 received voriconazole-based antifungal therapy for a median of 30.5 days. Only two patients survived after antifungal treatment.\u0000Conclusion: These cases illustrate CAPA complicated in critically ill COVID-19 patients. The challenges in diagnosis and poor outcomes of CAPA emphasize the clinical suspicion and needs for further investigation.","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46065847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-30DOI: 10.17966/jmi.2022.27.3.57
E. Yoo, S. Yoo, Marianne Isabel A. Sayo, J. H. Lee
types of scabies, although rare. If Darier's disease does not improve with proper treatment, it should be distinguished clinically and histologically from scabies.
疥疮的种类，虽然罕见。如果达里尔氏病经适当治疗不能改善，应在临床和组织学上与疥疮区分开来。
{"title":"A Case of Scabies Resembling Darier's Disease","authors":"E. Yoo, S. Yoo, Marianne Isabel A. Sayo, J. H. Lee","doi":"10.17966/jmi.2022.27.3.57","DOIUrl":"https://doi.org/10.17966/jmi.2022.27.3.57","url":null,"abstract":"types of scabies, although rare. If Darier's disease does not improve with proper treatment, it should be distinguished clinically and histologically from scabies.","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45347723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-30DOI: 10.17966/jmi.2022.27.3.51
Jinkyeong Kim, S. Yun, J. Lee
Fusarium species are widely distributed throughout the environment, and rarely cause infection in healthy individuals. Herein, we report a rare case of cutaneous infection by Fusarium solani in a healthy patient. A 64-year-old patient presented with a tender, erythematous, deep-seated nodule above the left ankle after an intralesional triamcinolone injection for lipoma was administered at a private clinic 1 month ago. Fungal hyphae were identified in subcutaneous tissue by skin biopsy using Gomori methenamine silver stain. Lactophenol cotton blue staining, fungal culturing, and 28S rRNA sequencing confirmed the presence of F. solani. After diagnosis, the patient was successfully treated with oral itraconazole.
{"title":"Cutaneous Infection by Fusarium solani in an\u0000Immunocompetent Patient","authors":"Jinkyeong Kim, S. Yun, J. Lee","doi":"10.17966/jmi.2022.27.3.51","DOIUrl":"https://doi.org/10.17966/jmi.2022.27.3.51","url":null,"abstract":"Fusarium species are widely distributed throughout the environment, and rarely cause infection in healthy individuals. Herein, we report a rare case of cutaneous infection by Fusarium solani in a healthy patient. A 64-year-old patient presented with a tender, erythematous, deep-seated nodule above the left ankle after an intralesional triamcinolone\u0000injection for lipoma was administered at a private clinic 1 month ago. Fungal hyphae were identified in subcutaneous tissue by skin biopsy using Gomori methenamine silver stain. Lactophenol cotton blue staining, fungal culturing, and 28S rRNA sequencing confirmed the presence of F. solani. After diagnosis, the patient was successfully treated with oral itraconazole.","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45557822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-30DOI: 10.17966/jmi.2022.27.3.55
H. Oh, S. Yoo, Marianne Isabel A. Sayo, J. H. Lee
Previous reports of sparganosis have verified the effects of immunosuppressive therapy to the onset of sparganosis 2 . Other reports have also found the absence of eosinophilia, presumably related to the immunosuppressive state of the patient. This indicates that the normal predictive value of eosinophilia on blood tests is unlikely to be present in patients with immunosuppression cases of multiple sparganosis which has been most frequently reported in immunocompromised patients. This underscores the importance of not only sus-pecting a parasitic infection in immunocompromised patients with a movable mass, but also taking all necessary steps to avoid the parasite from disseminating throughout the body including close observation.
{"title":"Clinical and Histopathological Findings of Multiple\u0000Sparganosis in a Patient with Primary Myelofibrosis","authors":"H. Oh, S. Yoo, Marianne Isabel A. Sayo, J. H. Lee","doi":"10.17966/jmi.2022.27.3.55","DOIUrl":"https://doi.org/10.17966/jmi.2022.27.3.55","url":null,"abstract":"Previous reports of sparganosis have verified the effects of immunosuppressive therapy to the onset of sparganosis 2 . Other reports have also found the absence of eosinophilia, presumably related to the immunosuppressive state of the patient. This indicates that the normal predictive value of eosinophilia on blood tests is unlikely to be present in patients with immunosuppression cases of multiple sparganosis which has been most frequently reported in immunocompromised patients. This underscores the importance of not only sus-pecting a parasitic infection in immunocompromised patients with a movable mass, but also taking all necessary steps to avoid the parasite from disseminating throughout the body including close observation.","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48506651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-30DOI: 10.17966/jmi.2022.27.3.60
Hyunmin Lee, T. Kim, Jisung Kim, Joonsoo Park
{"title":"Histopathological Findings of Primary\u0000Cutaneous Cryptococcosis","authors":"Hyunmin Lee, T. Kim, Jisung Kim, Joonsoo Park","doi":"10.17966/jmi.2022.27.3.60","DOIUrl":"https://doi.org/10.17966/jmi.2022.27.3.60","url":null,"abstract":"","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44477236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-30DOI: 10.17966/jmi.2022.27.3.45
H. D. Kook, Jiyoung Ahn, H. Jung
As coronavirus disease 2019 (COVID-19) spreads worldwide, various vaccines are being developed against the SARS-CoV-2 virus. These vaccines had to be developed in a relatively short period; therefore, they had to be manufactured using a method different from that of conventional vaccines. In addition, many people were vaccinated in a short period, and various side effects related to vaccination have been reported. In this article, we describe the injection site reactions and some unique skin reactions associated with COVID-19 vaccination, such as drug eruptions, bullous lesions, and foreign body reactions, with their possible causes.
{"title":"Cutaneous Adverse Reaction After COVID-19 Vaccination","authors":"H. D. Kook, Jiyoung Ahn, H. Jung","doi":"10.17966/jmi.2022.27.3.45","DOIUrl":"https://doi.org/10.17966/jmi.2022.27.3.45","url":null,"abstract":"As coronavirus disease 2019 (COVID-19) spreads worldwide, various vaccines are being developed against the SARS-CoV-2 virus. These vaccines had to be developed in a relatively short period; therefore, they had to be manufactured using a method different from that of conventional vaccines. In addition, many people were vaccinated in a short period, and various side effects related to vaccination have been reported. In this article, we describe the injection site reactions and some unique skin reactions associated with COVID-19 vaccination, such as drug eruptions, bullous lesions, and foreign body reactions, with their possible causes.","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44569616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-30DOI: 10.17966/jmi.2022.27.2.41
Hyun-Min Seo, J. H. Park, Ki Yeon Kim, J. Kim
{"title":"Gradual Improvement of Fungal Melanonychia:\u0000A Report of Serial Images","authors":"Hyun-Min Seo, J. H. Park, Ki Yeon Kim, J. Kim","doi":"10.17966/jmi.2022.27.2.41","DOIUrl":"https://doi.org/10.17966/jmi.2022.27.2.41","url":null,"abstract":"","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42616117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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