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Stressbusters: a pilot study investigating the effects of OMT on stress management in medical students. 压力克星:一项情节研究,调查 OMT 对医学生压力管理的影响。
IF 1.4 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-12-19 eCollection Date: 2025-05-01 DOI: 10.1515/jom-2024-0020
Robert Valencia, Gowtham Anche, Gabriela Do Rego Barros, Victor Arostegui, Henal Sutaria, Emily McAllister, Mary Banihashem, Mikhail Volokitin

Context: Medical students report high levels of perceived stress and burnout, especially during the preclinical years. The combination of physical stressors from poor posture, poor sleep quality, and mental stressors from the rigorous curriculum stimulates the sympathetic nervous system (SNS) to secrete cortisol. Previous studies have shown that persistent elevated cortisol levels are associated with negative health outcomes.

Objectives: We conducted an Institutional Review Board (IRB)-approved study to determine if regular osteopathic manipulative treatments (OMTs) could impact the stress levels of first-year osteopathic medical students (OMSs) at Touro College of Osteopathic Medicine (TouroCOM) Harlem campus by measuring physiologic stress through changes in weekly salivary cortisol levels, perceived emotional and psychological stress levels, and cognitive function.

Methods: We recruited 10 first-year OMSs who were not currently receiving external OMT outside of weekly coursework; other forms of external stress management, such as yoga or meditation, were not controlled for in this study. Utilizing a random number generator, the 10 student respondents were split into a control group that received no treatment and a treatment group that received 15 min of weekly OMT for 6 weeks. The treatment consisted of condylar decompression, paraspinal inhibition, and supine rib raising, which are techniques that are known to balance the SNS and parasympathetic nervous system (PNS). Cortisol levels were quantified by enzyme-linked immunosorbent assay (ELISA) cortisol immunoassay via salivary samples collected at the beginning of each weekly session, prior to treatment for the treatment group, at the same time of day each week. We also measured participants' weekly subjective perception of stress utilizing the College Student Stress Scale (CSSS) and cognitive function utilizing the Lumosity Performance Index (LPI). We conducted a two-tailed, unpaired t-test as well as a U test for the cortisol levels, given the smaller sample size and potential for a nonnormal distribution.

Results: A lower cortisol level was correlated to a higher optical density (OD), the logarithmic measure of percent transmission of light through a sample; analysis of our data from the ELISA cortisol immunoassay showed an average weekly change in OD (∆OD) for the treatment group of 0.0215 and an average weekly ∆OD of -0.0044 in the control group. The t-test showed p=0.0497, and our U test showed a p=0.0317. Both tests indicated a statistically significant decrease across the weekly salivary cortisol levels in the treatment group utilizing a p<0.05. An additional effect-size analysis supported our finding of a significant decrease in weekly cortisol levels in the treatment group, Cohen's d=1.460. Based on the CSSS responses, there was no significant difference in perceived stress b

背景:医学生报告高水平的感知压力和倦怠,特别是在临床前几年。不良姿势造成的身体压力、睡眠质量差以及严格课程造成的精神压力会刺激交感神经系统(SNS)分泌皮质醇。先前的研究表明,持续升高的皮质醇水平与负面的健康结果有关。目的:我们进行了一项机构审查委员会(IRB)批准的研究,通过测量每周唾液皮质醇水平、感知情绪和心理压力水平以及认知功能的变化,来确定常规整骨手法治疗(OMTs)是否会影响托罗整骨医学院(Touro College of osteopathic Medicine, TouroCOM)哈莱姆校区一年级整骨医学生(OMSs)的压力水平。方法:我们招募了10名目前在每周课程之外没有接受外部OMT的一年级OMSs;其他形式的外部压力管理,如瑜伽或冥想,在这项研究中没有受到控制。利用随机数生成器,将10名学生受访者分为不接受治疗的对照组和每周接受15 分钟OMT的治疗组,持续6周。治疗包括髁突减压、椎管旁抑制和仰卧肋抬高,这些技术已知可以平衡SNS和副交感神经系统(PNS)。皮质醇水平通过酶联免疫吸附法(ELISA)定量,皮质醇免疫分析法通过每周疗程开始时收集的唾液样本,治疗组在治疗前,每周同一时间。我们还利用大学生压力量表(CSSS)测量了参与者每周对压力的主观感知,并利用亮度表现指数(LPI)测量了参与者的认知功能。我们对皮质醇水平进行了双尾非配对t检验和U检验,因为样本量较小,而且可能是非正态分布。结果:较低的皮质醇水平与较高的光密度(OD)相关,OD是光通过样品透射百分比的对数测量;ELISA皮质醇免疫测定数据分析显示,治疗组平均每周OD变化(∆OD)为0.0215,对照组平均每周∆OD为-0.0044。t检验p=0.0497, U检验p=0.0317。两项测试都表明,在pd=1.460的情况下,治疗组每周唾液皮质醇水平有统计学显著下降。根据CSSS反应,对照组和治疗组在感知应激方面无显著差异(p=0.8655,双尾)。LPI分析显示认知表现差异无统计学意义(p=0.9265,双尾)。结论:我们的研究支持了针对SNS和PNS的OMT对皮质醇水平有显著影响的说法。虽然皮质醇水平的降低在统计学上是显著的,但更广泛的生理影响尚不清楚。需要进一步的研究来确定这种减少是否转化为有意义的临床益处。
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引用次数: 0
An osteopathic assessment of lower extremity somatic dysfunctions in runners. 跑步者下肢躯体功能障碍的骨科评估。
IF 1.4 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-12-05 eCollection Date: 2025-03-01 DOI: 10.1515/jom-2024-0006
Abbey Santanello, Mikhail Volokitin, Pamela Matthew, Anthony Modica, Chase McKellar, Krisha Thakkar, Mollie Schear, Angela Tai, Jeffrey Nagler, Sergio Suarez

Context: Runners often experience acute/chronic pain due to pre-existing structural somatic dysfunction and/or acquired various overuse injuries of the lower extremity, specifically affecting the ligaments, tendons, muscles, and bones. Common structural and function dysfunctions include but are not limited to patellofemoral pain syndrome (PFPS), Achilles tendonitis, iliotibial band syndrome (ITBS), ligamentous and muscle tears, muscle sprains/strains, stress fractures, pes planus, plantar fasciitis, and shin splints.

Objectives: The purpose of this study is to assess the correlation between acute and chronic pain, overuse injuries, and observational and palpatory findings upon evaluation to establish common trends of somatic dysfunctions and determine possible etiology of the pain/injury.

Methods: A total of 103 individuals were recruited (54.4% female, 45.6% male) aged 23-67 years old who consistently run at least 1 mile each week. They were categorized based on their weekly mileage - Novice (1-5 miles per week), Moderate (6-15), Advanced (15+) - with the intention to have a diversity of running types and to assess the data at various levels of commitment to running. The average was 7.8 miles/week with the range at 1 to 28 miles per week. The subjects included Touro students and individuals in the community. A history was collected through an anonymous survey on the individual's running habits, chronic/acute injuries, and any other relevant medical information. Data analyzing investigators were blinded to subjects' identifying information. Additionally, an osteopathic assessment was performed by two student investigators for reliability purposes and conducted under supervision by a board-certified osteopathic physician.

Results: Analysis of the data suggested an existing correlation between the number of somatic dysfunctions and years of running. A slight correlation was found between somatic dysfunctions and miles per week, sports injuries, time per week, and lower extremity pain. Finally, statistical correlations were also identified between the presence of pes planus and limb length discrepancy with three distinct muscular hypertonicities.

Conclusions: Runners' pains and injuries of the lower extremity are complex, and injury treatment and prevention is equally multifaceted. An association was found between both pes planus and limb length discrepancy with lower extremity muscle hypertonicity, suggesting the interrelated nature of these somatic dysfunctions. The survey concluded that many runners continue to run in pain and/or after significant injury but do not necessarily capitalize on existing support such as fitted shoes, custom arches, and osteopathic treatment that may help to minimize their risk of or treat injury. The intention of the research is to bring awareness to practitioners to the most common somatic dysfunctions such

背景:跑步者经常经历急性/慢性疼痛,这是由于先前存在的结构性躯体功能障碍和/或下肢获得的各种过度使用损伤,特别是影响韧带、肌腱、肌肉和骨骼。常见的结构和功能障碍包括但不限于髌股疼痛综合征(PFPS)、跟腱炎、髂胫束综合征(ITBS)、韧带和肌肉撕裂、肌肉扭伤/拉伤、应力性骨折、扁平足、足底筋膜炎和胫夹板。目的:本研究的目的是评估急性和慢性疼痛、过度使用损伤之间的相关性,以及评估后的观察和触诊结果,以建立躯体功能障碍的共同趋势,并确定疼痛/损伤的可能病因。方法:总共招募了103人(54.4%女性,45.6%男性),年龄在23-67岁,每周至少跑步1英里。他们根据每周的跑步里程进行分类——新手(每周1-5英里),中度(6-15英里),高级(15英里以上)——目的是让跑步类型多样化,并评估不同程度的跑步数据。平均为7.8英里/周,范围为1至28英里/周。研究对象包括图罗大学的学生和社区中的个人。通过匿名调查收集个人跑步习惯、慢性/急性损伤和任何其他相关医疗信息的历史。数据分析研究者不知道受试者的身份信息。此外,为了可靠性目的,由两名学生调查员进行整骨疗法评估,并在委员会认证的整骨疗法医生的监督下进行。结果:对数据的分析表明,身体功能障碍的数量与跑步年数之间存在相关性。身体功能障碍与每周运动里程、运动损伤、每周运动时间和下肢疼痛之间存在轻微的相关性。最后,我们还发现了三种不同的肌肉高张力的平足与肢体长度差异之间的统计学相关性。结论:跑步者下肢疼痛和损伤是复杂的,损伤的治疗和预防同样是多方面的。扁平足和肢体长度差异与下肢肌肉高张力之间存在关联,提示这些躯体功能障碍具有相互关联的性质。调查得出的结论是,许多跑步者在疼痛和/或严重受伤后继续跑步,但没有必要利用现有的支持,如合脚的鞋子、定制的足弓和整骨疗法,这些可能有助于减少他们的风险或治疗受伤。这项研究的目的是让从业者意识到最常见的躯体功能障碍,这样他们就可以建议跑步者进行步态分析和/或整骨疗法,这不仅可以更快地减轻伤害,还可以预防未来的伤害。
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引用次数: 0
Osteopathic approach to injuries of the overhead thrower's shoulder. 整骨疗法治疗头顶投掷运动员肩部损伤。
IF 1.4 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-12-02 eCollection Date: 2025-06-01 DOI: 10.1515/jom-2024-0031
Arthur J De Luigi, George Raum, Benjamin W King, Robert L Bowers

Overhead sports place a significant amount of stress on the shoulder. There are a variety of activities and sports with overhead athletes including both throwing (baseball, softball, football, cricket) and nonthrowing (tennis, swimming, volleyball) sports. Although all of these overhead motions can lead to pathology, a large focus has been on the consequences of overhead throwing. Overhead-throwing sports place forces on the joints, muscles, tendons, and ligaments that vary through the spectrum of athletes, as does the potential injuries that may be caused by these forces. The primary joints that are commonly injured in overhead sports are the shoulder and the elbow. The goal of this article is to discuss the impact of overhead motions on the shoulder, with a primary focus on throwing, as well as to highlight the osteopathic approach to assessment, treatment, management, and prevention.

头顶运动对肩膀造成很大的压力。这里有各种各样的活动和运动,包括投掷(棒球、垒球、足球、板球)和非投掷(网球、游泳、排球)运动。尽管所有这些头顶运动都可能导致病理,但人们一直关注的是头顶投掷的后果。抛顶运动对关节、肌肉、肌腱和韧带施加的力量因运动员的不同而不同,这些力量可能造成潜在的伤害。在头顶运动中最常受伤的关节是肩膀和肘部。本文的目的是讨论头顶运动对肩部的影响,主要集中在投掷,以及强调整骨疗法的评估、治疗、管理和预防。
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引用次数: 0
Elbow injuries in overhead throwing athletes: clinical evaluation, treatment, and osteopathic considerations. 高空投掷运动员的肘部损伤:临床评估、治疗和整骨疗法考虑因素。
IF 1.4 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-11-29 eCollection Date: 2025-05-01 DOI: 10.1515/jom-2024-0032
Benjamin W King, George M Raum, Arthur J De Luigi, Robert L Bowers

Injury to the elbow is very common in the throwing athlete and can potentially lead to long absences from play and, in the most severe scenarios, medical retirement. The throwing motion is a highly complex series of movements through the entire kinetic chain that results in very high angular velocities and valgus forces at the elbow joint. The repetitive nature of overhead throwing in combination with the high levels of accumulated force at the elbow puts both pediatric and adult athletes at risk of both acute and chronic overuse injuries of the elbow. This review provides an update on common injuries in the throwing athlete and covers clinical presentation, diagnosis, and treatment of these injuries.

肘部受伤在投掷运动员中非常常见,有可能导致运动员长期缺席比赛,最严重的情况下还可能导致退役。投掷动作是整个运动链中一系列高度复杂的运动,会在肘关节处产生极高的角速度和外翻力。高空投掷的重复性加上肘部累积的高水平力量,使儿童和成年运动员都面临肘部急性和慢性过度运动损伤的风险。本综述介绍了投掷运动员常见损伤的最新情况,包括这些损伤的临床表现、诊断和治疗。
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引用次数: 0
The role of osteopathic manipulative treatment for dystonia: a literature review. 整骨疗法对肌张力障碍的作用:文献综述。
IF 1.4 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-11-25 eCollection Date: 2025-04-01 DOI: 10.1515/jom-2024-0094
Davong D Phrathep, Zach Abdo, Mariam Tadros, Emily Lewandowski, John Evans

Context: Dystonia is a movement disorder that causes involuntary muscle contractions leading to abnormal movements and postures, such as twisting. Dystonia is the third most common movement disorder in the United States, with as many as 250,000 people affected. Because of its complexity, dystonia presents a significant challenge in terms of management and treatment. Despite limited research, osteopathic manipulative treatment (OMT) has been considered as an adjunctive treatment due to its inexpensive and noninvasive nature, as opposed to other modalities such as botulinum toxin injections, deep brain stimulation (DBS), and transcranial magnetic stimulation, which are often expensive and inaccessible. OMT treatments performed in case studies and series such as balanced ligamentous tension/articular ligamentous strain (BLT/ALS), muscle energy (ME), high-velocity low-amplitude (HVLA), and myofascial release (MFR) have shown reduction of pain and muscle hypertonicity, including in patients with dystonia.

Objectives: The studies reviewed in this paper provide a snapshot of the literature regarding the current evidence of OMT's role for dystonia.

Methods: A medical reference librarian conducted a thorough literature search across multiple databases including PubMed and Google Scholar to find articles relevant to the use of OMT for dystonia. The search employed a combination of Medical Subject Headings (MeSH) terms and keywords related to osteopathic medicine and dystonia to ensure precise retrieval of relevant articles within the last 20 years. Despite limited research on the topic, all four relevant reports found in the literature were selected for review.

Results: Of the four relevant reports, case series and studies highlighted the potential benefits of OMT in managing dystonia, particularly cervical dystonia and foot dystonia. OMT has shown promising results addressing pain, stiffness, and impaired motor function. In cases of foot dystonia in Parkinson's disease, OMT has helped improve gait and reduce pain by targeting somatic dysfunctions (SDs) associated with dystonia, such as abnormalities in foot progression angle (FPA) and musculoskeletal imbalances. Also, OMT has been found to alleviate symptoms of cervical dystonia, including tremors, muscle spasms, and neck stiffness. These interventions performed in case studies and series led to improvements in gait biomechanics in foot dystonia and overall symptom severity in patients with cervical dystonia.

Conclusions: Currently, botulinum toxin, oral medications, physical therapy, and rehabilitation are commonly utilized in managing dystonia. The studies reviewed in this paper suggest that these treatments may lead to improvements in pain and muscle hypertonicity in patients with dystonia. It is important to investigate whether factors such as the type of dystonia (eg, focal vs. segmental) a

背景:肌张力障碍是一种运动障碍疾病,会引起肌肉不自主收缩,导致异常动作和姿势,如扭动。肌张力障碍是美国第三大最常见的运动障碍,患者多达 25 万人。由于其复杂性,肌张力障碍在管理和治疗方面提出了巨大的挑战。尽管研究有限,但骨科手法治疗(OMT)因其廉价和非侵入性的特点,已被认为是一种辅助治疗方法,而肉毒素注射、脑深部刺激(DBS)和经颅磁刺激等其他方法通常价格昂贵且难以使用。在病例研究和系列研究中进行的 OMT 治疗,如平衡韧带张力/关节韧带拉伤(BLT/ALS)、肌肉能量(ME)、高速度低振幅(HVLA)和肌筋膜松解(MFR)等,都显示出疼痛和肌肉张力过高的减轻,包括肌张力障碍患者:本文回顾的研究提供了有关 OMT 在肌张力障碍中作用的现有证据的文献快照:一位医学参考图书管理员在多个数据库(包括 PubMed 和 Google Scholar)中进行了全面的文献检索,以找到与使用 OMT 治疗肌张力障碍相关的文章。该检索结合使用了医学主题词表(MeSH)中与整骨疗法和肌张力障碍相关的术语和关键词,以确保精确检索到过去 20 年内的相关文章。尽管对该主题的研究有限,但还是选择了文献中发现的所有四篇相关报告进行综述:结果:在四篇相关报告中,病例系列和研究强调了局部治疗法在治疗肌张力障碍方面的潜在益处,尤其是颈部肌张力障碍和足部肌张力障碍。在治疗疼痛、僵硬和运动功能受损方面,OMT 显示出了良好的效果。在帕金森病患者的足部肌张力障碍病例中,通过针对与肌张力障碍相关的躯体功能障碍(SDs),如足前倾角度(FPA)异常和肌肉骨骼失衡,OMT 有助于改善步态和减轻疼痛。此外,还发现 OMT 可减轻颈肌张力障碍的症状,包括震颤、肌肉痉挛和颈部僵硬。在病例研究和系列研究中进行的这些干预措施改善了足部肌张力障碍患者的步态生物力学以及颈肌张力障碍患者的整体症状严重程度:目前,肉毒毒素、口服药物、物理治疗和康复治疗是治疗肌张力障碍的常用方法。本文回顾的研究表明,这些治疗方法可改善肌张力障碍患者的疼痛和肌肉张力过高。研究肌张力障碍的类型(如局灶性与节段性)及其潜在病因(如特发性、创伤、感染、自身免疫、药物副作用)等因素是否会影响治疗效果非常重要。建议进一步研究探讨 OMT 在肌张力障碍治疗中的作用。
{"title":"The role of osteopathic manipulative treatment for dystonia: a literature review.","authors":"Davong D Phrathep, Zach Abdo, Mariam Tadros, Emily Lewandowski, John Evans","doi":"10.1515/jom-2024-0094","DOIUrl":"10.1515/jom-2024-0094","url":null,"abstract":"<p><strong>Context: </strong>Dystonia is a movement disorder that causes involuntary muscle contractions leading to abnormal movements and postures, such as twisting. Dystonia is the third most common movement disorder in the United States, with as many as 250,000 people affected. Because of its complexity, dystonia presents a significant challenge in terms of management and treatment. Despite limited research, osteopathic manipulative treatment (OMT) has been considered as an adjunctive treatment due to its inexpensive and noninvasive nature, as opposed to other modalities such as botulinum toxin injections, deep brain stimulation (DBS), and transcranial magnetic stimulation, which are often expensive and inaccessible. OMT treatments performed in case studies and series such as balanced ligamentous tension/articular ligamentous strain (BLT/ALS), muscle energy (ME), high-velocity low-amplitude (HVLA), and myofascial release (MFR) have shown reduction of pain and muscle hypertonicity, including in patients with dystonia.</p><p><strong>Objectives: </strong>The studies reviewed in this paper provide a snapshot of the literature regarding the current evidence of OMT's role for dystonia.</p><p><strong>Methods: </strong>A medical reference librarian conducted a thorough literature search across multiple databases including PubMed and Google Scholar to find articles relevant to the use of OMT for dystonia. The search employed a combination of Medical Subject Headings (MeSH) terms and keywords related to osteopathic medicine and dystonia to ensure precise retrieval of relevant articles within the last 20 years. Despite limited research on the topic, all four relevant reports found in the literature were selected for review.</p><p><strong>Results: </strong>Of the four relevant reports, case series and studies highlighted the potential benefits of OMT in managing dystonia, particularly cervical dystonia and foot dystonia. OMT has shown promising results addressing pain, stiffness, and impaired motor function. In cases of foot dystonia in Parkinson's disease, OMT has helped improve gait and reduce pain by targeting somatic dysfunctions (SDs) associated with dystonia, such as abnormalities in foot progression angle (FPA) and musculoskeletal imbalances. Also, OMT has been found to alleviate symptoms of cervical dystonia, including tremors, muscle spasms, and neck stiffness. These interventions performed in case studies and series led to improvements in gait biomechanics in foot dystonia and overall symptom severity in patients with cervical dystonia.</p><p><strong>Conclusions: </strong>Currently, botulinum toxin, oral medications, physical therapy, and rehabilitation are commonly utilized in managing dystonia. The studies reviewed in this paper suggest that these treatments may lead to improvements in pain and muscle hypertonicity in patients with dystonia. It is important to investigate whether factors such as the type of dystonia (eg, focal vs. segmental) a","PeriodicalId":36050,"journal":{"name":"Journal of Osteopathic Medicine","volume":" ","pages":"203-211"},"PeriodicalIF":1.4,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142693715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improving peripheral artery disease screening and treatment: a screening, diagnosis, and treatment tool for use across multiple care settings. 改善外周动脉疾病的筛查和治疗:可在多种医疗环境中使用的筛查、诊断和治疗工具。
IF 1.4 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-10-31 eCollection Date: 2025-04-01 DOI: 10.1515/jom-2024-0050
Kelly M Rudd, Kristie K Roberts, Cooper M Hamilton

Peripheral artery disease (PAD) is an atherosclerotic disease that contributes to significant morbidity and mortality, including loss of limb, myocardial infarction (MI), stroke, and death. Treatment options are often underutilized. A major limiting factor in PAD care is the ability to efficiently identify and screen at-risk patients. A PAD patient screening and clinician decision support tool was created to improve access to high-quality, evidence-based care to drive improved clinical outcomes. The tool identifies known PAD risk factors and presenting symptoms, in combination with objective data obtained via the ankle-brachial index (ABI). The tool utilizes this data to drive PAD diagnosis, risk assessment, and treatment, and it is adaptable across multiple care settings, by varied health professions. The implementation of a PAD screening and treatment toolkit enhances anticoagulation and PAD stewardship, and it has been integrated into use across various care settings.

外周动脉疾病(PAD)是一种动脉粥样硬化性疾病,可导致严重的发病率和死亡率,包括肢体缺失、心肌梗死(MI)、中风和死亡。治疗方案往往未得到充分利用。PAD 护理的一个主要限制因素是有效识别和筛查高危患者的能力。我们创建了一个 PAD 患者筛查和临床医生决策支持工具,以提高获得高质量循证护理的机会,从而改善临床疗效。该工具结合通过踝肱指数(ABI)获得的客观数据,识别已知的 PAD 危险因素和主要症状。该工具利用这些数据来推动 PAD 诊断、风险评估和治疗,并可适用于多种医疗环境和不同的医疗专业。PAD 筛查和治疗工具包的实施加强了抗凝和 PAD 管理,并已在各种护理环境中整合使用。
{"title":"Improving peripheral artery disease screening and treatment: a screening, diagnosis, and treatment tool for use across multiple care settings.","authors":"Kelly M Rudd, Kristie K Roberts, Cooper M Hamilton","doi":"10.1515/jom-2024-0050","DOIUrl":"10.1515/jom-2024-0050","url":null,"abstract":"<p><p>Peripheral artery disease (PAD) is an atherosclerotic disease that contributes to significant morbidity and mortality, including loss of limb, myocardial infarction (MI), stroke, and death. Treatment options are often underutilized. A major limiting factor in PAD care is the ability to efficiently identify and screen at-risk patients. A PAD patient screening and clinician decision support tool was created to improve access to high-quality, evidence-based care to drive improved clinical outcomes. The tool identifies known PAD risk factors and presenting symptoms, in combination with objective data obtained via the ankle-brachial index (ABI). The tool utilizes this data to drive PAD diagnosis, risk assessment, and treatment, and it is adaptable across multiple care settings, by varied health professions. The implementation of a PAD screening and treatment toolkit enhances anticoagulation and PAD stewardship, and it has been integrated into use across various care settings.</p>","PeriodicalId":36050,"journal":{"name":"Journal of Osteopathic Medicine","volume":" ","pages":"163-171"},"PeriodicalIF":1.4,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142548072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of the Strong Hearts program at two years post program completion. 强心计划完成两年后的效果。
IF 1.4 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-10-30 eCollection Date: 2025-05-01 DOI: 10.1515/jom-2024-0083
Bruce E Murphy, Peyton D Card, Leybi Ramirez-Kelly, Brandon Wensley, Robert E Heidel

Context: This is a follow-up to the original published article, Effects of the Strong Hearts Program after a Major Cardiovascular Event in Patients with Cardiovascular Disease.

Objectives: This study evaluated the long-term efficacy of the Strong Hearts program up to 2 years after program completion.

Methods: All study participants who initially completed the Strong Hearts program between 2020 and 2021 (n=128) were contacted at 12 months and 24 months following the date of program completion. A phone survey was conducted to see if any significant post-cardiovascular events or readmissions to the hospital occurred, and self-reported dates of any occurrences were recorded. Hospital readmissions and cardiac-related procedures were cross-referenced with the hospital's electronic medical record. A chi-square goodness-of-fit analysis was utilized to compare the observed rates of categorical outcomes vs. expected rates yielded from the empirical literature.

Results: The rate of all-cause readmission at 6 months post-program completion was 2/120 (1.7 %), compared to the expected rate of 50 %, χ2(1) = 112.13, p<0.001. The readmission rate at 1 year post-program completion was 17/120 (14.2 %), vs. the expected rate of 45 %, χ2(1) = 46.09, p<0.001, and at 2 years post-program completion, the readmission rate was 24/120 (20.0 %) compared to the expected rate of 53.8 %, χ2(1) = 56.43, p<0.001. Ten participants (8.3 %) had a subsequent cardiac procedure within 2 years of completing the program, including two requiring percutaneous coronary intervention (1.7 %) and eight requiring coronary artery bypass grafting (CABG, 6.7 %), compared to the expected rates of 13.4 and 57.74 %, χ2(1)=153.08, p<0.001, respectively. Mortality at 2 years post-program completion was 2/128 (1.6 %), compared to 23.4 %, χ2(1)=34.13, p<0.001.

Conclusions: Efficacy of the Strong Hearts program continued at 6 months, 1 year, and 2 years post-program completion in terms of all-cause readmission, subsequent cardiac event, and all-cause mortality.

背景:这是对最初发表的文章《心血管疾病患者重大心血管事件后的强心计划效果》的后续研究:本研究评估了 "强心计划 "在计划完成后两年内的长期疗效:在项目完成后的 12 个月和 24 个月,与 2020 年至 2021 年间初步完成 Strong Hearts 项目的所有研究参与者(128 人)取得联系。他们接受了电话调查,以了解是否发生了重大心血管事件或再次入院,并记录了自我报告的发生日期。再入院情况和心脏相关程序与医院的电子病历进行了交叉对比。利用卡方拟合优度分析将观察到的分类结果比率与经验文献得出的预期比率进行比较:结果:计划完成后 6 个月的全因再入院率为 2/120(1.7%),而预期率为 50%,χ2(1) = 112.13,p2(1) = 46.09,p2(1) = 56.43,p2(1)=153.08,p2(1)=34.13,p结论:在全因再入院、后续心脏事件和全因死亡率方面,"强心 "计划的疗效在计划完成后的 6 个月、1 年和 2 年仍在持续。
{"title":"Effects of the Strong Hearts program at two years post program completion.","authors":"Bruce E Murphy, Peyton D Card, Leybi Ramirez-Kelly, Brandon Wensley, Robert E Heidel","doi":"10.1515/jom-2024-0083","DOIUrl":"10.1515/jom-2024-0083","url":null,"abstract":"<p><strong>Context: </strong>This is a follow-up to the original published article, Effects of the Strong Hearts Program after a Major Cardiovascular Event in Patients with Cardiovascular Disease.</p><p><strong>Objectives: </strong>This study evaluated the long-term efficacy of the Strong Hearts program up to 2 years after program completion.</p><p><strong>Methods: </strong>All study participants who initially completed the Strong Hearts program between 2020 and 2021 (n=128) were contacted at 12 months and 24 months following the date of program completion. A phone survey was conducted to see if any significant post-cardiovascular events or readmissions to the hospital occurred, and self-reported dates of any occurrences were recorded. Hospital readmissions and cardiac-related procedures were cross-referenced with the hospital's electronic medical record. A chi-square goodness-of-fit analysis was utilized to compare the observed rates of categorical outcomes vs. expected rates yielded from the empirical literature.</p><p><strong>Results: </strong>The rate of all-cause readmission at 6 months post-program completion was 2/120 (1.7 %), compared to the expected rate of 50 %, χ<sup>2</sup>(1) = 112.13, p<0.001. The readmission rate at 1 year post-program completion was 17/120 (14.2 %), vs. the expected rate of 45 %, χ<sup>2</sup>(1) = 46.09, p<0.001, and at 2 years post-program completion, the readmission rate was 24/120 (20.0 %) compared to the expected rate of 53.8 %, χ<sup>2</sup>(1) = 56.43, p<0.001. Ten participants (8.3 %) had a subsequent cardiac procedure within 2 years of completing the program, including two requiring percutaneous coronary intervention (1.7 %) and eight requiring coronary artery bypass grafting (CABG, 6.7 %), compared to the expected rates of 13.4 and 57.74 %, χ<sup>2</sup>(1)=153.08, p<0.001, respectively. Mortality at 2 years post-program completion was 2/128 (1.6 %), compared to 23.4 %, χ<sup>2</sup>(1)=34.13, p<0.001.</p><p><strong>Conclusions: </strong>Efficacy of the Strong Hearts program continued at 6 months, 1 year, and 2 years post-program completion in terms of all-cause readmission, subsequent cardiac event, and all-cause mortality.</p>","PeriodicalId":36050,"journal":{"name":"Journal of Osteopathic Medicine","volume":" ","pages":"225-227"},"PeriodicalIF":1.4,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142523262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perspectives of osteopathic medical students on preclinical urology exposure: a single institution cross-sectional survey. 骨科医学生对泌尿外科临床前接触的看法:一项单一机构横断面调查。
IF 1.4 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-10-23 eCollection Date: 2025-02-01 DOI: 10.1515/jom-2023-0284
Ryan Wong, Harvey N Mayrovitz

Context: There is an increasing number of medical school graduates opting for surgical specialties, and the osteopathic applicant match rate for urology is lower than that of allopathic applicants. Factors influencing this may include a lack of interest, perceived challenges in matching into urology, insufficient urology mentorship, limited research opportunities, and inadequate osteopathic representation in urology.

Objectives: The objective of this survey is to assess osteopathic medical students' perspectives on pursuing urology and enhancing preclinical exposure to and knowledge of urology.

Methods: A 20-question survey addressing experiences and the factors influencing osteopathic medical students' specialty selection and their interest in and perception of urology was designed by the investigators on Research Electronic Data Capture (REDCap) software. This survey was distributed via email listserv to all current osteopathic medical students attending Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine over 2 months. Responses were collected and analyzed utilizing Fisher's exact test.

Results: Among 150 respondents, 91 % found mentors crucial in selecting a medical specialty, 95 % emphasized the importance of early exposure, and 68 % lacked familiarity with urology, with more M1 students unfamiliar with urology compared to M2 (70.4 % vs. 59 %). A larger proportion of combined M1 and M2 (preclinical) students are considering urology as a specialty compared to M3 and M4 (clinical) students who are actively on rotations (56.5 % vs. 28.6 %; p=0.0064). Also, a greater percentage of males are considering urology compared to females (64.2 % vs. 42.7 %; p=0.0164). Among those considering urology (n=75), 57.3 % lack awareness of urology's scope, and 84 % report no preclinical discussions with urologists. Those students who report that they are considering urology value early exposure significantly more than others (98.7 % vs. 78.7 %; p=0.0001). They also express greater interest in having a core urology course (73.3 % vs. 38.7 %; p<0.0001). More urology-considering students are interested in extracurricular urology-related workshops, seminars, or conferences (61.3 % vs. 17.3 %; p<0.0001). Students who are considering urology as a specialty show greater interest in having a mentorship program (85.3 % vs. 28 %; p<0.0001).

Conclusions: Results suggested that increased urology exposure during the preclinical years is important. Urology elective offerings and urology mentorship are of high interest among those considering urology. However, additional investigation is needed to determine the impact of preclinical urology curricula implementation on urology match outcomes.

背景:越来越多的医学院毕业生选择外科专业,而骨科医生申请泌尿外科的匹配率低于全科医生申请者。影响因素可能包括缺乏兴趣、认为泌尿外科匹配存在挑战、泌尿外科导师不足、研究机会有限以及泌尿外科的骨科医生代表不足:本调查旨在评估骨科医学生对攻读泌尿外科以及加强临床前接触和了解泌尿外科的看法:研究人员利用研究电子数据采集(REDCap)软件设计了一项包含 20 个问题的调查,内容涉及影响骨科医学生专业选择的经验和因素,以及他们对泌尿外科的兴趣和看法。该调查通过电子邮件列表服务向诺瓦东南大学基兰-帕特尔骨科医学院的所有骨科医学生发放,为期两个月。收集到的回复采用费雪精确检验法进行分析:在150名受访者中,91%的人认为导师对选择医学专业至关重要,95%的人强调早期接触的重要性,68%的人不熟悉泌尿科,与M2相比,更多的M1学生不熟悉泌尿科(70.4%对59%)。与正在轮转的 M3 和 M4(临床)学生相比,更多的 M1 和 M2(临床前)学生正在考虑将泌尿外科作为一个专业(56.5% 对 28.6%;P=0.0064)。此外,与女生相比,考虑选择泌尿外科的男生比例更高(64.2% 对 42.7%;P=0.0164)。在考虑就读泌尿外科的学生(人数=75)中,57.3% 的学生对泌尿外科的范围缺乏了解,84% 的学生表示没有与泌尿科医生进行过临床前讨论。那些表示正在考虑泌尿外科的学生对早期接触的重视程度明显高于其他学生(98.7% 对 78.7%;P=0.0001)。他们还对开设泌尿外科核心课程表示出更大的兴趣(73.3% 对 38.7%;P=0.0001):结果表明,在临床前几年增加泌尿外科的接触非常重要。泌尿外科选修课和泌尿外科导师制在考虑就读泌尿外科的学生中兴趣很高。然而,要确定泌尿外科临床前课程的实施对泌尿外科匹配结果的影响,还需要进行更多的调查。
{"title":"Perspectives of osteopathic medical students on preclinical urology exposure: a single institution cross-sectional survey.","authors":"Ryan Wong, Harvey N Mayrovitz","doi":"10.1515/jom-2023-0284","DOIUrl":"10.1515/jom-2023-0284","url":null,"abstract":"<p><strong>Context: </strong>There is an increasing number of medical school graduates opting for surgical specialties, and the osteopathic applicant match rate for urology is lower than that of allopathic applicants. Factors influencing this may include a lack of interest, perceived challenges in matching into urology, insufficient urology mentorship, limited research opportunities, and inadequate osteopathic representation in urology.</p><p><strong>Objectives: </strong>The objective of this survey is to assess osteopathic medical students' perspectives on pursuing urology and enhancing preclinical exposure to and knowledge of urology.</p><p><strong>Methods: </strong>A 20-question survey addressing experiences and the factors influencing osteopathic medical students' specialty selection and their interest in and perception of urology was designed by the investigators on Research Electronic Data Capture (REDCap) software. This survey was distributed via email listserv to all current osteopathic medical students attending Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine over 2 months. Responses were collected and analyzed utilizing Fisher's exact test.</p><p><strong>Results: </strong>Among 150 respondents, 91 % found mentors crucial in selecting a medical specialty, 95 % emphasized the importance of early exposure, and 68 % lacked familiarity with urology, with more M1 students unfamiliar with urology compared to M2 (70.4 % vs. 59 %). A larger proportion of combined M1 and M2 (preclinical) students are considering urology as a specialty compared to M3 and M4 (clinical) students who are actively on rotations (56.5 % vs. 28.6 %; p=0.0064). Also, a greater percentage of males are considering urology compared to females (64.2 % vs. 42.7 %; p=0.0164). Among those considering urology (n=75), 57.3 % lack awareness of urology's scope, and 84 % report no preclinical discussions with urologists. Those students who report that they are considering urology value early exposure significantly more than others (98.7 % vs. 78.7 %; p=0.0001). They also express greater interest in having a core urology course (73.3 % vs. 38.7 %; p<0.0001). More urology-considering students are interested in extracurricular urology-related workshops, seminars, or conferences (61.3 % vs. 17.3 %; p<0.0001). Students who are considering urology as a specialty show greater interest in having a mentorship program (85.3 % vs. 28 %; p<0.0001).</p><p><strong>Conclusions: </strong>Results suggested that increased urology exposure during the preclinical years is important. Urology elective offerings and urology mentorship are of high interest among those considering urology. However, additional investigation is needed to determine the impact of preclinical urology curricula implementation on urology match outcomes.</p>","PeriodicalId":36050,"journal":{"name":"Journal of Osteopathic Medicine","volume":" ","pages":"71-77"},"PeriodicalIF":1.4,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142509574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The negative effects of long COVID-19 on cardiovascular health and implications for the presurgical examination. 长 COVID-19 对心血管健康的负面影响及对手术前检查的影响。
IF 1.4 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-10-17 eCollection Date: 2025-03-01 DOI: 10.1515/jom-2024-0109
Hannah L Stimart, Brittany Hipkins
<p><strong>Context: </strong>In 2019, emergence of the novel and communicable severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection took scientific communities by surprise and imposed significant burden on healthcare systems globally. Although the advent of this disease piqued the interest of academic centers, healthcare systems, and the general public, there is still much yet to be elucidated regarding epidemiology, pathophysiology, and long-term impacts of coronavirus disease 2019 (COVID-19). It has been established that long COVID-19 can impact multiple organ systems, including the cardiovascular system, unfavorably. Although the pathophysiology of this damage is not well understood, adverse sequelae may range from chest pain and arrhythmias to heart failure (HF), myocardial infarction, or sudden cardiac death. For any postacute COVID-19 patient requiring a surgical procedure, the potential for cardiac injury secondary to long COVID-19 must be considered in the preoperative cardiac examination.</p><p><strong>Objectives: </strong>This literature review serves to add to the growing body of literature exploring postacute cardiovascular outcomes of COVID-19, with a focus on presurgical cardiac clearance in the adult patient. Specifically, this review studies the prevalence of cardiovascular symptomatology including chest pain, arrhythmias, blood pressure changes, myo-/pericarditis, HF, cardiomyopathy, orthostatic intolerance, and thromboembolism. Although current evidence is scarce in both quality and quantity, it is the goal that this review will highlight the negative impacts of long COVID-19 on cardiovascular health and encourage providers to be cognizant of potential sequelae in the context of the presurgical examination.</p><p><strong>Methods: </strong>For this study, peer-reviewed and journal-published articles were selected based on established inclusion and exclusion criteria to address the question "How does long COVID-19 impact the presurgical cardiac examination of an adult scheduled to undergo a noncardiac procedure?" Inclusion criteria included human studies conducted in adult patients and published in peer-reviewed journals up until May 2024 examining the effects of long-COVID-19 infection on the cardiovascular system. Exclusion criteria eliminated unpublished reports, preprints, duplicate articles, literature regarding coronavirus strains other than COVID-19, studies regarding post-COVID-19 vaccination complications, animal studies, and studies conducted in people younger than 18 years of age. A total of 6,675 studies were retrieved from PubMed and Google Scholar. Following screening, 60 studies were included in final consideration.</p><p><strong>Results: </strong>Cardiovascular symptoms of postacute COVID-19 infection were encountered with the following percentages prevalence (total numbers of articles mentioning symptom/total number of articles [60]): chest pain (83.3), arrhythmias (88.3), hypertension (40.0), hyp
背景:2019 年,新型传染性严重急性呼吸系统综合征冠状病毒 2(SARS-CoV-2)感染的出现令科学界措手不及,并给全球医疗保健系统带来了沉重负担。尽管这种疾病的出现引起了学术中心、医疗保健系统和公众的兴趣,但关于冠状病毒病 2019(COVID-19)的流行病学、病理生理学和长期影响,仍有许多问题有待阐明。已经证实,长期的 COVID-19 会对包括心血管系统在内的多个器官系统产生不利影响。虽然这种损害的病理生理学尚不十分清楚,但不良后遗症的范围可能从胸痛和心律失常到心力衰竭(HF)、心肌梗塞或心脏性猝死。对于任何需要进行外科手术的急性 COVID-19 后患者,在术前心脏检查中必须考虑长 COVID-19 继发心脏损伤的可能性:本文献综述旨在补充日益增多的探讨 COVID-19 急性期后心血管后果的文献,重点关注成年患者的术前心脏检查。具体而言,本综述研究了心血管症状的发生率,包括胸痛、心律失常、血压变化、心肌炎/心包炎、心房颤动、心肌病、正压性不耐受和血栓栓塞。虽然目前的证据在质量和数量上都很匮乏,但本综述旨在强调长期 COVID-19 对心血管健康的负面影响,并鼓励医疗服务提供者在术前检查时认识到潜在的后遗症:本研究根据既定的纳入和排除标准选择同行评审和期刊发表的文章,以解决 "长 COVID-19 对计划接受非心脏手术的成人的术前心脏检查有何影响?纳入标准包括截至 2024 年 5 月在同行评审期刊上发表的、针对成人患者进行的人类研究,这些研究探讨了长 COVID-19 感染对心血管系统的影响。排除标准包括未发表的报告、预印本、重复文章、有关 COVID-19 以外冠状病毒毒株的文献、有关接种 COVID-19 疫苗后并发症的研究、动物研究以及在 18 岁以下人群中开展的研究。从 PubMed 和 Google Scholar 共检索到 6675 项研究。经过筛选,60 项研究被纳入最终考虑范围:结果:急性 COVID-19 感染后出现的心血管症状的比例如下(提及症状的文章总数/文章总数 [60]):胸痛(83.3)、心律失常(88.3)、高血压(40.0)、低血压(16.7)、心肌炎(80.0)、心包炎(51.7)、HF(70.0)、心肌病(55.0)、正压性不耐受(56.7)和血栓栓塞事件(85.0):持续的 COVID 症状可能会对患者的体格检查、血液化验、心电图 (ECG)、影像学检查和/或超声心动图检查产生负面影响。由于心脏性猝死、心肌炎、中风和心肌梗死的风险增加,即使在急性 COVID-19 感染前身体健康的人也会出现此类风险,因此与长期 COVID 相关的心脏疾病需要手术前候选人特别注意。在获得更多具体的科学证据之前,应根据已采用的最佳实践对这些患者进行护理,临床医生应保持较低的门槛,在手术前进行更广泛的心脏检查。
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引用次数: 0
Reduction in deep organ-space infection in gynecologic oncology surgery with use of oral antibiotic bowel preparation: a retrospective cohort analysis. 使用口服抗生素肠道制剂减少妇科肿瘤手术中的深部器官间隙感染:一项回顾性队列分析。
IF 1.4 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-10-09 eCollection Date: 2025-05-01 DOI: 10.1515/jom-2024-0099
Kathryn Kennedy, Jennifer Gaertner-Otto, Eav Lim

Context: Deep organ-space infection (OSI) following gynecologic surgery is a source of patient morbidity and mortality. There is currently conflicting evidence regarding the use of bowel preparation prior to gynecologic surgery to reduce the rates of infection. For the additional purpose of improving patient recovery at our own institution, a retrospective cohort study compared the rate of deep OSI in patients who received oral antibiotic bowel preparation per Nichols-Condon bowel preparation with metronidazole and neomycin.

Objectives: The primary aim of this study was to compare the rate of deep organ-space surgical site infection in gynecologic surgery before and after institution of an oral antibiotic bowel preparation, thus assessing whether the preparation is associated with decreased infection rate. The secondary objective was to identify other factors associated with deep organ-space site infection.

Methods: A retrospective cohort study was performed. Demographic and surgical data were collected via chart review of 1,017 intra-abdominal surgeries performed by gynecologic oncologists at a single institution from April 1, 2019 to December 1, 2021. Of these, 778 met the inclusion criteria; 444 did not receive preoperative oral antibiotic bowel preparation, and 334 did receive preoperative bowel preparation. Odds ratios (ORs) were calculated, and a logistic regression model was utilized for categorical variables. Multivariable regression analysis was performed.

Results: A total of 778 patients were included. Deep OSI rate in patients who did not receive oral antibiotic bowel preparation was 2.3 % compared to 0.3 % (OR 0.13, confidence interval [CI] 0.06-1.03, p=0.02) in patients who did. Receiving oral antibiotic bowel preparation predicted absence of deep OSI (OR 0.04, CI 0.00-0.87, p=0.04). Laparotomy (OR 20.1, CI 1.6-250.2, p=0.02) and Asian race (OR 60.8, CI 2.6-1,380.5, p=0.01) were related to increased rates of deep OSI.

Conclusions: Oral antibiotic bowel preparation predicts a reduced risk of deep OSI. This preparation is inexpensive and low-risk, and thus these clinically significant results support a promising regimen to improve surgical outcomes, and provide guidance for prospective larger studies.

背景:妇科手术后的深部器官间隙感染(OSI)是导致患者发病和死亡的原因之一。目前,关于在妇科手术前使用肠道准备以降低感染率的证据并不一致。为了改善患者的恢复情况,本机构还进行了一项回顾性队列研究,比较了接受口服抗生素肠道准备和使用甲硝唑和新霉素进行尼可康肠道准备的患者的深部 OSI 发生率:本研究的主要目的是比较妇科手术中口服抗生素肠道准备前后的深部器官间隙手术部位感染率,从而评估该准备是否与感染率降低有关。次要目标是确定与深部器官间隙部位感染相关的其他因素:进行了一项回顾性队列研究。从 2019 年 4 月 1 日至 2021 年 12 月 1 日,通过病历审查收集了由一家机构的妇科肿瘤专家实施的 1,017 例腹腔内手术的人口统计学和手术数据。其中,778例符合纳入标准;444例未接受术前口服抗生素肠道准备,334例接受了术前肠道准备。计算了比值比 (OR),并对分类变量采用了逻辑回归模型。进行了多变量回归分析:结果:共纳入 778 名患者。未接受口服抗生素肠道准备的患者的深度 OSI 率为 2.3%,而接受口服抗生素肠道准备的患者的深度 OSI 率为 0.3%(OR 0.13,置信区间 [CI]0.06-1.03,P=0.02)。接受口服抗生素肠道准备的患者不会出现深部 OSI(OR 0.04,CI 0.00-0.87,P=0.04)。开腹手术(OR 20.1,CI 1.6-250.2,P=0.02)和亚洲人种(OR 60.8,CI 2.6-1,380.5,P=0.01)与深部OSI发生率增加有关:结论:口服抗生素肠道制剂可降低深部 OSI 的风险。结论:口服抗生素肠道准备可降低深部 OSI 的风险。这种准备方法成本低、风险小,因此这些具有临床意义的结果支持了一种可改善手术预后的方案,并为更大规模的前瞻性研究提供了指导。
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引用次数: 0
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Journal of Osteopathic Medicine
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