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A rare case of frontotemporal dementia with amyotrophic lateral sclerosis 一例罕见的额颞叶痴呆伴肌萎缩侧索硬化症
Q4 Psychology Pub Date : 2021-07-01 DOI: 10.4103/amh.amh_2_21
M. Bhat, G. Kini, S. Amithabh, A. Kakunje
Frontotemporal dementia (FTD) is a neurodegenerative disorder characterized by progressive degeneration of the frontal and temporal lobes which typically presents with cognitive symptoms. Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive degeneration of upper and lower motor neurons, leading to symptoms of motor weakness. We present a case of behavioral variant of FTD with ALS. The patient presented with changes in his behavior followed by impaired memory and progressive weakness of bilateral upper limbs. Patient eventually developed difficulty swallowing and recognizing faces too. The case highlights the association between FTD and ALS.
额颞叶痴呆(FTD)是一种以额叶和颞叶进行性变性为特征的神经退行性疾病,通常表现为认知症状。肌萎缩侧索硬化症(ALS)是一种神经退行性疾病,其特征是上下运动神经元进行性退化,导致运动无力症状。我们报告了一例伴有ALS的FTD行为变异病例。患者表现为行为改变,随后记忆力受损,双侧上肢逐渐衰弱。患者最终出现吞咽困难和面部识别困难。该病例强调了FTD和ALS之间的关联。
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引用次数: 0
Fluvoxamine-induced galactorrhea: A case series 氟伏沙明致溢乳1例
Q4 Psychology Pub Date : 2021-07-01 DOI: 10.4103/AMH.AMH_54_20
Hiral Kotadia, K. Rawat, S. Reddy
Galactorrhea is a very distressing symptom, especially for unmarried females, and medication-induced galactorrhea is a common etiological factor. Among psychotropics, antipsychotic-induced galactorrhea is commonly reported. However, there is dearth of literature regarding antidepressant-induced galactorrhea. There have been few case reports of galactorrhea induced by the use of selective serotonin reuptake inhibitors such as escitalopram and sertraline. Fluvoxamine is one of the routine first-line medications prescribed for obsessive–compulsive disorder (OCD). However, reports about fluvoxamine-induced galactorrhea have been scant. We report two cases of OCD who developed galactorrhea on treatment with fluvoxamine. One patient had hyperprolactinemia while other had euprolactinemic galactorrhea. In both cases, galactorrhea reversed on stopping of fluvoxamine. The complex interaction of serotonin and dopamine in the pathophysiology of hyperprolactinemia is discussed.
溢乳是一种非常痛苦的症状,尤其是对未婚女性来说,药物诱导的溢乳是常见的病因。在抗精神病药物中,抗精神病药引起的溢乳是常见的报道。然而,关于抗抑郁药引起的溢乳的文献却很少。很少有使用选择性血清素再摄取抑制剂如艾司西酞普兰和舍曲林引起溢乳的病例报告。氟伏沙明是治疗强迫症(OCD)的常规一线药物之一。然而,关于氟伏沙明引起的溢乳的报道却很少。我们报告两例强迫症患者在氟伏沙明治疗后出现溢乳。一名患者患有高泌乳素血症,另一名患者则患有泌乳素血症性溢乳。在这两种情况下,氟伏沙明停药后,溢乳逆转。讨论了血清素和多巴胺在高泌乳素血症病理生理学中的复杂相互作用。
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引用次数: 0
Impact of pandemic on the mental health of doctors working in a district COVID-19 hospital 大流行对某地区COVID-19医院医生心理健康的影响
Q4 Psychology Pub Date : 2021-07-01 DOI: 10.4103/amh.amh_74_20
Therissa Benerji, Sarath Bodepudi, Srikanth Lella, M. Kodali
Background: COVID-19 pandemic can significantly affect the mental health of doctors as they stand in the front line of this crisis. The psychiatric consequences, in part, can be due to the stress the doctors are subjected to due to their close involvement in the treatment of infected patients. Some of the other reasons are related to the fear of transmission to their families and concerns about the health of self and family, stigmatization, and rejection. Aims: To assess the levels of depression, anxiety, and stress among doctors working in district COVID hospital, note the possible association of life events with the mental health of the doctors during the current situation and address the coping styles they have sought to endure the current crisis. Materials and Methods: An online survey is conducted to assess the psychological responses of doctors during the COVID-19 outbreak. It consisted of four subsections covering (1) sociodemographic data and information on individuals' working conditions, (2) Depression Anxiety and Stress Scale-21, (3) presumptive stressful life events scale, (4) Brief-COPE. Statistical Analysis Used: Statistical analysis was done using SPSS version 25. Results: Of the 353 participants, 80 had symptoms of depression, 151 anxiety, and 74 stress. Significant levels of depression were found among doctors involved in the direct care of patients with COVID-19 compared to those not involved in direct care. Undesirable events were found to be greater in number than desirable events. Concerning coping strategies, we found the more frequent use of adaptive coping strategies compared with maladaptive coping strategies among respondents. Conclusion: COVID-19 pandemic has a sizeable psychological impact on the mental health of doctors involved in direct and indirect care of patients with COVID-19.
背景:新冠肺炎大流行可能会严重影响医生的心理健康,因为他们站在这场危机的前线。精神方面的后果在一定程度上可能是由于医生密切参与感染患者的治疗而承受的压力。其他一些原因与害怕传播给家人以及对自身和家人健康的担忧、污名化和排斥有关。目的:评估在地区新冠肺炎医院工作的医生的抑郁、焦虑和压力水平,注意在当前情况下生活事件与医生心理健康的可能联系,并解决他们在当前危机中寻求的应对方式。材料和方法:进行一项在线调查,以评估新冠肺炎爆发期间医生的心理反应。它由四个子部分组成,涵盖(1)关于个人工作条件的社会人口统计数据和信息,(2)抑郁、焦虑和压力量表-21,(3)假定压力生活事件量表,(4)简要COPE。使用的统计分析:使用SPSS 25版进行统计分析。结果:353名参与者中,80人有抑郁症状,151人有焦虑症状,74人有压力症状。与未参与直接护理的医生相比,参与直接护理新冠肺炎患者的医生抑郁症水平显著。不良事件的数量多于理想事件。关于应对策略,我们发现在受访者中,与不适应的应对策略相比,适应性应对策略的使用频率更高。结论:新冠肺炎大流行对参与新冠肺炎患者直接和间接护理的医生的心理健康有相当大的心理影响。
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引用次数: 0
The male nursing students' childhood traumas and attitudes toward violence: A cross-sectional study in Turkey 土耳其护生童年创伤与暴力态度的横断面研究
Q4 Psychology Pub Date : 2021-07-01 DOI: 10.4103/amh.amh_16_21
S. Çelik, A. Öztürk, E. Karahan
Context: To prevent domestic violence against women, it is critical to identify men's attitudes toward violence itself. Aims: This study aimed to examine the relationship between the experience of childhood trauma and attitudes toward violence in male nursing students. Methods: This study included 276 male nursing students. Data were collected using a descriptive information form, the Childhood Trauma Questionnaire Short Form (CTQ-SF) and the Attitudes toward Violence Scale (ATVS). Results: Participants' mean age was 21.61 ± 2.01, 47.5% of them experienced violence, and 31.2% witnessed it. They had low levels of childhood trauma and negative attitudes toward violence. There was a weak-positive relationship between their ATVS mean scores and the mean emotional abuse, physical abuse, and sexual abuse subscale scores (CTQ-SF) (P < 0.05). Conclusions: Nursing training programs should include courses on violence and its perception in society to increase awareness. Because childhood trauma negatively affects the violence perception, there should be support programs provided to students who have experienced it.
背景:为了防止对妇女的家庭暴力,确定男性对暴力本身的态度是至关重要的。目的:本研究旨在探讨男护生童年创伤经历与暴力态度的关系。方法:研究对象为276名男护生。采用描述性信息表、儿童创伤问卷简表(CTQ-SF)和暴力态度量表(ATVS)收集数据。结果:参与者平均年龄为21.61±2.01岁,有暴力经历者占47.5%,亲历者占31.2%。他们的童年创伤程度较低,对暴力持消极态度。他们的ATVS平均得分与精神虐待、身体虐待和性虐待分量表平均得分呈弱正相关(P < 0.05)。结论:护理培训计划应包括暴力及其在社会中的认知课程,以提高认识。因为童年创伤会对暴力认知产生负面影响,所以应该为经历过暴力的学生提供支持项目。
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引用次数: 8
Yoga therapy in psychiatry: Myths and misconceptions 精神病学中的瑜伽疗法:神话和误解
Q4 Psychology Pub Date : 2021-01-01 DOI: 10.4103/amh.amh_64_21
R. Karri, A. Bhavanani, M. Ramanathan, V. Mopidevi
Yoga is a philosophy, a science, and an art, the value of which is underrecognized. Many myths and misconceptions are prevailing among the common people as well as mental health professionals, resulting in an underutilization of this effective tool that has the potential for health promotion and disease prevention. It has been established to be an effective adjunct in treating many psychiatric and psychosomatic problems. Scientific, evidence.based data are accumulating from global research institutions. Salutogenesis or wellness concept with a holistic approach is the hallmark of the yoga. This article is a review attempting to dispel some of the popular myths and misconceptions.
瑜伽是一门哲学,一门科学,也是一门艺术,它的价值被低估了。在普通民众和精神卫生专业人员中普遍存在许多神话和误解,导致这一具有促进健康和预防疾病潜力的有效工具未得到充分利用。它已被证实是治疗许多精神和心身问题的有效辅助手段。科学证据。基于全球研究机构的数据正在积累。健康的概念与整体的方法是瑜伽的标志。这篇文章是一篇综述,试图消除一些流行的神话和误解。
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引用次数: 0
Attitude towards COVID-19 vaccine among the general public in south India: A cross sectional study 印度南部公众对COVID-19疫苗的态度:一项横断面研究
Q4 Psychology Pub Date : 2021-01-01 DOI: 10.4103/amh.amh_33_21
G. Godasi, R. Donthu, A. Mohammed, R. Pasam, Sri Tiruveedhula
Introduction: Coronavirus disease-19 (COVID-19) is a novel infection that sets off a pandemic in a short period. Research has been going on to develop safe and effective vaccines and around 150 are in the process of development. In India, two vaccines have been given emergency approval. There has been a rise in hesitancy toward vaccination not only in India but also worldwide. Materials and Methodology: The study included 697 participants who were not vaccinated. The study questionnaire was administered through online Google Forms and included informed consent, sociodemographic details, questions related to COVID-19 infection and vaccine, and vaccine attitude examination (VAX) scale. Results: Among the 697 participants, 216 (31%) were not willing to get vaccinated. Those with prevailing mental (P = 0.011) or physical health (P < 0.001) problems were of negative opinion toward vaccination because of unforeseen complications. Participants with lower education (P = 0.041), skilled to semi-skilled job (P = 0.028), and joint family (P = 0.006) opined that vaccination was more of commercial profiteering for manufacturing companies. Participants who were married (P = 0.010) and living in a joint family (P = 0.009) setting were more inclined toward a preference for natural immunity. Conclusion: The study highlights that 69% of participants were willing to take the COVID-19 vaccine. Various measures can be taken by different stakeholders to improve the positive attitude. As medical professions, we can improve the positive attitude by actively taking the vaccine and educating the local people about the benefits.
简介:冠状病毒病-19 (COVID-19)是一种短时间内引发大流行的新型感染。开发安全有效疫苗的研究一直在进行,大约有150种疫苗正在开发过程中。在印度,已经紧急批准了两种疫苗。不仅在印度,而且在世界范围内,对疫苗接种的犹豫有所增加。材料和方法:该研究包括697名未接种疫苗的参与者。研究问卷通过在线谷歌表格进行,包括知情同意、社会人口学详细信息、与COVID-19感染和疫苗相关的问题以及疫苗态度检查(VAX)量表。结果:697名参与者中,216名(31%)不愿意接种疫苗。普遍存在精神(P = 0.011)或身体健康(P < 0.001)问题的患者由于不可预见的并发症而对疫苗接种持否定态度。受教育程度较低(P = 0.041)、熟练至半熟练工作(P = 0.028)和共同家庭(P = 0.006)的参与者认为疫苗接种更多的是制造公司的商业暴利。已婚(P = 0.010)和生活在联合家庭(P = 0.009)的参与者更倾向于选择自然免疫。结论:该研究强调,69%的参与者愿意接种COVID-19疫苗。不同的利益相关者可以采取各种措施来改善积极的态度。作为医疗专业人员,我们可以通过积极接种疫苗和教育当地人接种疫苗的好处来提高他们的积极态度。
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引用次数: 7
Effectiveness of buprenorphine in detoxification and naltrexone in relapse prevention of tramadol-dependent patients: A case series 丁丙诺啡解毒和纳曲酮预防曲马多依赖患者复发的有效性:一个病例系列
Q4 Psychology Pub Date : 2021-01-01 DOI: 10.4103/amh.amh_39_21
V. Avula
Tramadol hydrochloride is a centrally acting synthetic analgesic drug. Its analgesic properties are weak agonist at mu- and kappa-opioid receptors, blockade of reuptake serotonin (5-HT), and norepinephrine at synaptic cleft inhibiting pain transmission. This case series is about the treatment of nine patients who were dependent on tramadol. All patients satisfied criteria for opioid dependency International Classification of Diseases, 10th Revision diagnostic criteria. WHO treatment guidelines for opioid detoxification using Buprenorphine and relapse prevention using oral naltrexone were followed. Detoxification with buprenorphine did not alleviate all withdrawal symptoms. Craving toward tramadol and the cost of naltrexone was a reason to relapse in patients. Cost and failure to address craving lead to noncompliance with naltrexone. Partial agonists like buprenorphine and long-acting agonist like methadone should be used to detoxify and prevent relapse in patients dependent on tramadol.
盐酸曲马多是一种中枢作用的合成镇痛药。其镇痛特性是μ和κ阿片受体的弱激动剂,阻断再摄取血清素(5-HT),以及突触间隙的去甲肾上腺素抑制疼痛传递。本系列病例是关于9名依赖曲马多的患者的治疗。所有患者均符合阿片类药物依赖性国际疾病分类第10版诊断标准。遵循世界卫生组织使用丁丙诺啡进行阿片类药物解毒和使用口服纳曲酮预防复发的治疗指南。丁丙诺啡排毒并不能缓解所有的戒断症状。对曲马多的渴望和纳曲酮的成本是患者复发的原因。成本和未能解决渴望导致不遵守纳曲酮。丁丙诺啡等部分激动剂和美沙酮等长效激动剂应用于依赖曲马多的患者的解毒和预防复发。
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引用次数: 0
A prospective study of major depressive disorder among COVID 19 survivors at a tertiary care hospital 三级护理医院COVID-19幸存者重度抑郁障碍的前瞻性研究
Q4 Psychology Pub Date : 2021-01-01 DOI: 10.4103/AMH.AMH_72_20
Kajalpreet Kaur, V. Patel, Parveen Kumar, D. Vasavada, L. Nerli, D. Tiwari
Background: The COVID-19 pandemic has impacted physical health, wellbeing, and mental health, which has a disastrous effect on the health system. Among disorders emerging in the aftermath of a disaster, depression is the second most common. Aim: The current study was aimed to estimate the prevalence of major depressive disorder (MDD) at two-time points in individuals who have been hospitalized for the treatment of COVID 19. Materials and Methods: A prospective study was carried out from May 2020 to October 2020 at a tertiary care center among patients discharged after recovery from novel coronavirus (COVID 19). A diagnostic clinical interview was conducted to diagnose MDD, and its severity in patients who had recovered from COVID 19 using “Patient Health Questionnaire (PHQ-9)” at the time of discharge and 1 month after their discharge from the hospital. Statistical Analysis: Descriptive statistics and Chi-square test were used for the analysis, P < 0.05 was considered statistically significant. Results: A total of 440 participants participated in the study. Out of them, 30.90% of participants met the criteria for MDD at the time of discharge and 19.5% at 1 month post-discharge. Participants who stayed for more than 14 days, were admitted to intensive care unit (ICU) and those with co-morbid medical illness had a higher prevalence of MDD. Conclusion: High prevalence of MDD was observed at the time of discharge among hospitalized participants. Longer duration of hospital stay and admission in ICU is associated with more unpleasant events, subsequently resulting in higher rates of morbidity, such as depression.
背景:新冠肺炎大流行影响了身体健康、幸福感和心理健康,对卫生系统产生了灾难性影响。在灾难后出现的疾病中,抑郁症是第二常见的。目的:目前的研究旨在评估因治疗COVID 19而住院的患者在两个时间点的重度抑郁障碍(MDD)的患病率。材料和方法:于2020年5月至2020年10月在一家三级护理中心对新型冠状病毒(COVID 19)康复后出院的患者进行前瞻性研究。在出院时和出院后1个月,使用“患者健康问卷(PHQ-9)”进行诊断性临床访谈,以诊断新冠肺炎19康复患者的MDD及其严重程度。统计学分析:采用描述性统计和卡方检验进行分析,P<0.05被认为具有统计学意义。结果:共有440名参与者参与了这项研究。其中,30.90%的参与者在出院时符合MDD标准,19.5%在出院后1个月符合MDD标准。停留超过14天的参与者被送入重症监护室(ICU),而那些患有合并疾病的参与者的MDD患病率更高。结论:住院患者出院时MDD的患病率较高。住院时间和入住重症监护室的时间越长,越会发生不愉快的事件,从而导致更高的发病率,如抑郁症。
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引用次数: 3
Proportion of subjects remaining abstinent following alcohol de-addiction treatment and factors associated with abstinence - A 3 months prospective cohort study 戒酒治疗后保持戒断的受试者比例及与戒断相关的因素——一项为期3个月的前瞻性队列研究
Q4 Psychology Pub Date : 2021-01-01 DOI: 10.4103/AMH.AMH_49_20
Ariya Nair, Praveen Arathil, Dinesan Narayanan
Aims: The aim is to study prevalence of abstinence rates for 3 months follow-up in individuals of alcohol dependence undergoing de-addiction treatment. Also to assess for possible co-relation between sociodemographic, clinical, personality, cognitive functioning and laboratory variables of relapsed and abstinent individuals. Subjects and Methods: Eighty-six individuals who were admitted for alcohol deaddiction treatment were taken for the study after taking consent. Sociodemographic and clinical variables were assessed using a pro forma. The Mini-International Neuropsychiatric Interview was administered to rule out other disorders. Clinical Institute Withdrawal Assessment of Alcohol, revised scale to assess the severity of withdrawal. Personality was assessed using 16PF. The Tower of London (ToL) test was used to assess executive function. Individuals were followed up after discharge till 3 months from the admission date to assess for the maintenance of abstinence. Results: Out of 86 individuals, only 24 individuals maintained abstinence at 3 months. About 72.08% of those who had previous deaddiction treatment did not maintain abstinence or were lost to follow-up. Duration of hospitalization was significantly more in abstinent individuals (15.63 ± 6.31, P = 0.001). On 16PF individuals who did not maintain abstinence had higher perfectionism scores (5.97 ± 1.9, P = 0.027) similarly on the ToL test they had lower scores on the total number of problems solved on the minimum number of moves (7.02 ± 1.76, P = 0.001). Conclusion: There is the low rate of abstinence among individuals having undergone deaddiction treatment at the end of 3 months. Modifying treatment for individuals who have past relapses, personality disturbances, and avoiding early discharge may help in increasing the abstinence rate.
目的:研究接受戒毒治疗的酒精依赖患者3个月随访的禁欲率。同时评估复发和禁欲个体的社会人口学、临床、个性、认知功能和实验室变量之间可能的共同关系。受试者和方法:86名接受酒精抑制治疗的患者在征得同意后被纳入研究。使用形式评估社会形态和临床变量。迷你国际神经精神病学访谈是为了排除其他疾病。临床研究所酒精戒断评估,用于评估戒断严重程度的修订量表。人格评估采用16PF。伦敦塔(ToL)测试用于评估执行功能。出院后随访至入院后3个月,以评估禁欲的维持情况。结果:在86个个体中,只有24个个体在3个月时保持禁欲。约72.08%的既往接受过戒毒治疗的患者没有保持禁欲或失去了随访。禁欲个体的住院时间明显更长(15.63±6.31,P=0.001)。在不保持禁欲的16PF个体中,完美主义得分更高(5.97±1.9,P=0.027)。同样,在ToL测试中,他们在最小移动次数下解决的问题总数上得分更低(7.02±1.76,P=0.001在3个月结束时接受戒毒治疗的个体中的禁欲。对既往有复发、人格障碍的患者进行改良治疗,避免提前出院,可能有助于提高禁欲率。
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引用次数: 1
Defeat and entrapment in the pathogenesis of suicidal behavior 自杀行为发病机制中的失败和陷阱
Q4 Psychology Pub Date : 2021-01-01 DOI: 10.4103/AMH.AMH_50_20
S. Nukala, Srinivas Singisetti, Archana Vinnakota, Shvetha Chilikuri, Abhilash Garapati, Vidya Sanapala, Laxman Nambaru
Introduction: Human behavior is very complex and driven by different motivations. At times, we find a deviant escape behavior in some situations, characterized by streaks of self-destruction or “suicidal behavior.” Defeat and entrapment have been hypothesized as central to this behavior. Aim: We aimed to study the relationship between defeat, entrapment, suicidal ideation, and suicidal attempt. Materials and Methods: This study was a cross-sectional study of fifty patients who attempted suicide and survived the attempt. When medically fit for psychological assessment, they were approached in a person in the hospital psychiatric ward. These patients were subjected to a detailed psychiatric interview, and any psychiatric illness in the patients was diagnosed using the Diagnostic and Statistical Manual of Mental Disorders V criteria. They were assessed on the defeat and entrapment scales by Gilbert and Allan. The Modified Scale for Suicidal Ideation by Ivan W. Miller was used to determine the presence or absence of suicidal ideation and severity of suicidal ideation. Results: The presence of a current depressive disorder diagnosis and planning of attempt had a significant association with higher scores on internal entrapment, total entrapment, defeat, and suicidal ideation scales. The scores on defeat, internal entrapment, total entrapment, and suicidal ideation scales correlated positively and highly significantly. Conclusion: Entrapment and defeat are identified as important in the pathogenesis of depression and self-harm. Arrested escape and flight appear as motivation for suicidal behavior.
引言:人类行为非常复杂,由不同的动机驱动。有时,我们会在某些情况下发现一种异常的逃跑行为,其特征是一连串的自我毁灭或“自杀行为”。失败和诱捕被认为是这种行为的核心。目的:我们旨在研究失败、诱捕、自杀意念和自杀企图之间的关系。材料和方法:本研究是对50名自杀未遂并在自杀未遂后幸存的患者进行的横断面研究。当他们的身体状况适合进行心理评估时,他们会在医院精神科病房的一个人那里接受治疗。这些患者接受了详细的精神科访谈,并使用《精神障碍诊断和统计手册》第五版标准对患者的任何精神疾病进行诊断。吉尔伯特和艾伦对他们的失败和诱捕程度进行了评估。Ivan W.Miller的《自杀意念修正量表》用于确定自杀意念的存在与否以及自杀意念的严重程度。结果:当前抑郁障碍的诊断和尝试计划的存在与内部诱捕、总诱捕、失败和自杀意念量表的高分显著相关。失败、内部诱捕、总诱捕和自杀意念量表的得分呈正相关且高度显著。结论:压抑和挫败在抑郁症和自残的发病机制中具有重要意义。逃跑和逃亡被捕似乎是自杀行为的动机。
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引用次数: 0
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Archives of Mental Health
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