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Psychometric properties of Kessler's Psychological Distress Scale (K10) in cancer patients 癌症患者Kessler心理困扰量表(K10)的心理测量特征
Q4 Psychology Pub Date : 2022-07-01 DOI: 10.4103/amh.amh_104_21
Manish N. Thakre, Harshal Sathe, M. Talapalliwar
Context: Kessler's Psychological Distress Scale (K10) is a self-rated, easy-to-apply scale to measure psychological distress. The suitability of its use in treatment-seeking cancer patients in the clinical setup has not been studied. Aims: The aim was to assess the psychometric properties and associations of K10 with sociodemographic and clinical variables and depression levels in the cancer patients visiting the hospital. Settings and Design: The research was a cross-sectional, observational, descriptive study conducted in the oncology outpatient department of a public hospital. Materials and Methods: The data were collected from 155 cancer patients using semi-structured pro forma for sociodemographic and illness-related information. K10 and Patient Health Questionnaire-9 were used to quantify psychological distress and depression. Statistical Analysis Used: The factor structure of Kessler's 10-item scale was assessed by confirmatory factor analysis, and Cronbach's alpha was calculated as a measure of internal consistency. Given the nonnormal distribution of quantitative data, nonparametric tests were used to analyze the association of K10 scores with sociodemographic and clinical variables and depression scores. Results: The K10 showed good internal consistency (Cronbach's alpha = 0.914) in the cancer patients. In confirmatory factor analysis using structural equation modeling, the single-factor and two-factor models could not adequately fit across goodness-of-fit indices. There was a significant association between the levels of psychological distress and depression in cancer patients. Conclusion: K10, in its current form, is a reliable instrument to measure psychological distress. However, a need-based modification of the existing scale is required in treatment-seeking cancer patients.
背景:Kessler心理困扰量表(K10)是一种自评的、易于应用的心理困扰量表。其在寻求治疗的癌症患者中使用的适用性尚未进行临床研究。目的:目的是评估到医院就诊的癌症患者的心理测量特性以及K10与社会人口学、临床变量和抑郁水平的关系。背景和设计:本研究是一项横断面、观察性、描述性研究,在一家公立医院肿瘤门诊进行。资料与方法:采用半结构化的社会人口学和疾病相关信息表格收集155例癌症患者的数据。使用K10和患者健康问卷-9来量化心理困扰和抑郁。使用统计分析:采用验证性因子分析评估Kessler十项量表的因子结构,并计算Cronbach’s alpha作为内部一致性的度量。鉴于定量数据的非正态分布,采用非参数检验分析K10评分与社会人口学、临床变量和抑郁评分的相关性。结果:K10在肿瘤患者中具有良好的内部一致性(Cronbach’s alpha = 0.914)。在结构方程模型的验证性因子分析中,单因素和双因素模型在拟合优度指标上不能充分拟合。癌症患者的心理困扰程度和抑郁程度之间存在显著关联。结论:目前形式的K10是一种可靠的心理困扰测量工具。然而,在寻求治疗的癌症患者中,需要对现有的量表进行基于需求的修改。
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引用次数: 0
Quantitative electroencephalography – A promising biomarker in children with attention deficit/hyperactivity disorder 定量脑电图——一种有前途的注意力缺陷/多动障碍儿童生物标志物
Q4 Psychology Pub Date : 2022-07-01 DOI: 10.4103/amh.amh_24_22
Mini Sharma, Manoj Kumar, S. Kushwaha, D. Kumar
Background: Attention-deficit/hyperactivity disorder (ADHD) is marked by inattention, hyperactivity, and impulsivity. Experimental studies have reported increased theta activity and reduced beta activity on electroencephalography (EEG), although theta wave tends to appear during meditative, drowsy, hypnotic, or sleeping states. Aims: We aimed to study EEG changes in children with significant severity of ADHD. Settings and Design: A cross-sectional study was designed for the children with ADHD presenting to the Child and Adolescent Psychiatry Outpatient Department (OPD) of IHBAS. Methodology: A total of 33 ADHD children in the age group of 5–12 years attending OPD were included in the study after qualifying the inclusion and exclusion criteria for the study. DSM-5 criteria were used to make the diagnosis of ADHD and severity was assessed using Conners' Rating Scale-Revised Parent short version. The children with more than 50% score on the Conners Scale were included in the study. The quantification of the recorded EEG was done using Fast Fourier Transformation by New Natus NeuroWorks computer software. Statistical Analysis: The data were analyzed using SPSS version 23.0. Results: Around 3/4th of participants in the study showed elevated theta: beta ratio results on qEEG. Conclusions: Although ADHD is marked by inattention, hyperactivity, and impulsivity, children with ADHD showed marked elevated theta: beta ratio indicating raised slow-wave changes in cortical activity, thus concluding quantitative EEG as a promising biomarker in children with ADHD.
背景:注意缺陷/多动障碍(ADHD)以注意力不集中、多动和冲动为特征。实验研究报告了脑电图(EEG)上的θ波活动增加和β波活动减少,尽管θ波倾向于在冥想、昏昏欲睡、催眠或睡眠状态下出现。目的:我们旨在研究严重ADHD儿童的脑电图变化。背景和设计:一项横断面研究是为在IHBAS儿童和青少年精神病学门诊(OPD)就诊的ADHD儿童设计的。方法:在符合研究的纳入和排除标准后,共有33名5-12岁的ADHD儿童在OPD就诊。采用DSM-5标准对ADHD进行诊断,并采用Conners评定量表-修订家长简短版对ADHD的严重程度进行评估。康纳斯量表得分在50%以上的儿童被纳入研究。用New Natus NeuroWorks软件对记录的脑电图进行快速傅立叶变换定量分析。统计分析:采用SPSS 23.0版本对数据进行分析。结果:大约3/4的参与者在qEEG上显示出高的θ: β比值。结论:尽管ADHD以注意力不集中、多动和冲动为特征,但ADHD儿童的theta: beta比明显升高,表明皮层活动的慢波变化增加,因此定量脑电图是一种有希望的ADHD儿童生物标志物。
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引用次数: 0
Neuroleptic-induced tardive dystonia in young patients suffering from psychosis 年轻精神病患者的抗精神病药诱导的迟发性肌张力障碍
Q4 Psychology Pub Date : 2022-07-01 DOI: 10.4103/amh.amh_10_22
Amey Y. Angane, Aditya R. Anvekar, Prerna Keshari, V. Unnithan
Tardive dystonia is one of the extrapyramidal syndromes that start after long-term use of dopamine receptor antagonists. Tardive dystonia is underdiagnosed and often misdiagnosed; some of the treatment possibilities are hardly known among psychiatrists and are notorious for being resistant to treatment. Here, we present a set of two cases who had come with neuroleptic-induced tardive dystonia, initially given oral tetrabenazine and injectable botulinum toxin, but they did not respond. They got better after treatment with the combination of oral baclofen and electroconvulsive therapy (ECT). ECT is thought to prevent the super sensitization of postsynaptic dopamine receptors that contribute to the development of tardive states. Baclofen is a presynaptic gamma-aminobutyric acid receptor agonist primarily used to treat spasticity. Both may have acted synergistically to treat the dystonia. Tardive dystonia needs to be ruled out in patients with a history of long-term antipsychotic medication use. Consultant liaison with psychiatrists will be of paramount importance in the timely management of these cases. The combination of ECT and baclofen may be an effective choice for patients of schizophrenia with tardive dystonia developed in the course of neuroleptic treatment. However, further controlled studies are needed to develop and refine the guidelines for managing it.
迟发性肌张力障碍是在长期使用多巴胺受体拮抗剂后开始的锥体外系综合征之一。迟发性肌张力障碍诊断不足,常被误诊;一些治疗的可能性在精神科医生中几乎不为人所知,并且因抗拒治疗而臭名昭著。在这里,我们介绍了一组两名患者,他们患有神经抑制剂诱导的迟发性肌张力障碍,最初口服四苯那嗪和注射肉毒杆菌毒素,但没有反应。口服巴氯芬联合电休克治疗后病情好转。ECT被认为可以防止突触后多巴胺受体的超敏,这种受体有助于发展迟缓状态。巴氯芬是一种突触前γ-氨基丁酸受体激动剂,主要用于治疗痉挛。两者可能协同作用治疗肌张力障碍。有长期抗精神病药物使用史的患者需要排除迟发性肌张力障碍。顾问与精神科医生的联络对于及时处理这些病例至关重要。ECT和巴氯芬联合治疗可能是精神分裂症患者在抗精神病药物治疗过程中出现的迟发性肌张力障碍的有效选择。然而,还需要进一步的对照研究来制定和完善管理它的指导方针。
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引用次数: 0
Dr DS Raju oration award-andhra pradesh psychiatry conference 2021-2022 拉朱博士奖-安得拉邦精神病学2021-2022年会议
Q4 Psychology Pub Date : 2022-07-01 DOI: 10.4103/amh.amh_61_22
G. Ramanarao
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引用次数: 0
A cross-sectional study of frequency, type, and lethality of deliberate self-harm in bipolar affective disorder patients presenting to tertiary care center 双相情感障碍患者在三级护理中心故意自残的频率、类型和致死率的横断面研究
Q4 Psychology Pub Date : 2022-07-01 DOI: 10.4103/amh.amh_135_21
Fakirappa B Ganiger, Somashekhar Bijjal, A. Safeekh, Manisha Sharma
Introduction: Deliberate self-harm (DSH) is one of the leading causes of death and a major public health problem worldwide. According to the World Health Organization, DSH has increased by 60% over the past 50 years, of which 90% of victims had a psychiatric disorder. Aims and Objectives: The aim is to analyze the frequency, type, and lethality of DSH in bipolar affective disorder (BPAD) patients. Materials and Methods: This study included 150 patients diagnosed to have BPAD. Specially designed sociodemographic pro forma was used to record basic profile. DSH inventory was administered on BPAD patients who presented with DSH to analyze the type and lethality. Diagnosis of BPAD was made according to the International Classification of Diseases, tenth revision. Data were recorded, compiled, and analyzed using frequency and percentage with the IBM SPSS Statistics for Windows, Version 24.0. Results: The frequency of DSH was found to be 33%, out of which 38 (35%) patients had manic episode and 11 (30%) patients had depressive episode. The most common type of DSH was found to be cutting self with sharp or blunt objects and consumption of poison with frequency of 12 (24.5%) each. The second most common DSH was banging head, which was present in (11) 22.4% of patients. Conclusion: BPAD is associated with increased risk of DSH compared to the general population. The most common type of DSH was cutting self with sharp objects followed by consumption of poison. Patients who presented with DSH in depressive episode and severe mania had more lethal modes of DSH.
蓄意自残(DSH)是导致死亡的主要原因之一,也是世界范围内的一个主要公共卫生问题。根据世界卫生组织的数据,在过去的50年里,DSH增加了60%,其中90%的受害者患有精神疾病。目的和目的:目的是分析双相情感障碍(BPAD)患者DSH的频率、类型和致死率。材料和方法:本研究纳入了150例诊断为BPAD的患者。特别设计的社会人口统计表格用于记录基本概况。对出现DSH的BPAD患者进行DSH清查,分析DSH的类型和致死率。BPAD的诊断依据《国际疾病分类》第十版。使用IBM SPSS Statistics for Windows, Version 24.0对数据进行记录、编译和分析,使用频率和百分比。结果:DSH发生率为33%,其中狂躁发作38例(35%),抑郁发作11例(30%)。最常见的DSH类型是用锐器或钝器自残和服毒,频率各为12例(24.5%)。第二常见的DSH是撞击头,出现在11.22.4%的患者中。结论:与一般人群相比,BPAD与DSH风险增加有关。最常见的DSH类型是用尖锐物体割伤自己,然后服用毒药。在抑郁发作和严重躁狂中出现DSH的患者有更多致命的DSH模式。
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引用次数: 0
Anxiety, Depression and Barriers to Mental Health Services among patients with Neurological disorders: Brief report from a tertiary care centre in South India 神经系统疾病患者的焦虑、抑郁和获得精神健康服务的障碍:印度南部一个三级保健中心的简要报告
Q4 Psychology Pub Date : 2022-07-01 DOI: 10.4103/amh.amh_177_21
R. Innamuri, A. Mukherjee, Bhuvaneshwari Sethuraman, A. Rachana, V. Mathew
There is high prevalence of psychological distress in patients diagnosed with neurological disorders. A cross-sectional study was done among inpatients from the department of neurology in a tertiary care centre in South India to assess prevalence of anxiety, depression, and barriers to mental health-care utilization. Anxiety and depression were estimated using the Hospital Anxiety and Depression Scale (HADS). There is a high prevalence of psychological distress among the study participants. Proactive inquiry and screening of distress by the treating team may help identify psychological distress. Patients are more conforming and open to treating doctor. Barriers to mental health-care utilization included stigma, patient perception regarding treating doctor's attitude, patients' perception regarding distress, and doctor's perception regarding patient distress. There is a need for measures to alleviate stigma.
在被诊断为神经系统疾病的患者中,心理困扰的患病率很高。在印度南部一家三级保健中心的神经内科住院患者中进行了一项横断面研究,以评估焦虑、抑郁的患病率和精神保健利用的障碍。使用医院焦虑和抑郁量表(HADS)评估焦虑和抑郁。在研究参与者中,心理困扰的患病率很高。治疗小组主动询问和筛选痛苦可能有助于识别心理痛苦。患者对治疗医生更加顺从和开放。利用精神卫生保健的障碍包括耻辱、患者对治疗医生态度的看法、患者对痛苦的看法以及医生对患者痛苦的看法。有必要采取措施减轻耻辱感。
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引用次数: 0
Stigma among COVID-19 patients in South India-A cross-sectional study 南印度COVID-19患者的耻辱感——横断面研究
Q4 Psychology Pub Date : 2022-07-01 DOI: 10.4103/amh.amh_189_21
Kannappa V. Shetty, Anekal C. Amaresha, Urmila Bamney, R. Rajkumar, Prerna Srivastava, G. Mahesh
Background: COVID-19 has a significant biopsychosocial impact on the lives of people who are infected, with the stigma associated with the illness being one of the major issues. However, the level of stigma based on demographics, gender differences, hospital-based or home-based care is yet to be explored. Hence, this study aimed to infer the level of stigma between these groups in the urban district of south India. Materials and Methods: This cross-sectional study recruited 50 participants who were recently infected with COVID-19 and were receiving either hospital or home-based care. The stigma was assessed using a standardized questionnaire which has four domains. MannWhitney U test was conducted to analyze the data. Results: Median age is 54 years and the majority of the participants are male (74%). The mean score of enacted stigma subscale was 4.48, disclosure fear was 2.34, internalized stigma was 2.82, perceived externalized stigma was 7.32 and the total stigma mean score was 17. The perceived externalized stigma subscale was higher in males (7.57 ± 5.96) when compared to females 6.62 ± 5.53. Total stigma scores were higher for males 17.2 ± 10.1 when compared to females 16.2 ± 10.5. The total stigma score was more (17 ± 10.3) among home isolated COVID patients as compared to hospitalized patients (16.9 ± 10.2). Conclusion: Increased levels of stigma among COVID-19 patients have various important psychosocial implications. This study highlights the need for larger prospective cohort studies to further understand stigma in the context of COVID-19.
背景:新冠肺炎对感染者的生活产生了重大的生物心理社会影响,与疾病相关的污名是主要问题之一。然而,基于人口统计、性别差异、医院或家庭护理的污名程度尚待探索。因此,本研究旨在推断印度南部城市地区这些群体之间的耻辱程度。材料和方法:这项横断面研究招募了50名最近感染新冠肺炎并接受医院或家庭护理的参与者。使用标准化问卷对污名进行了评估,该问卷有四个领域。对数据进行了Mann-Whitney U检验。结果:中位年龄为54岁,大多数参与者为男性(74%)。实施污名分量表的平均得分为4.48,披露恐惧为2.34,内化污名为2.82,感知外化污名为7.32,总污名平均得分为17。与女性6.62±5.53相比,男性的感知外化污名分量表更高(7.57±5.96)。男性的总污名得分为17.2±10.1,而女性为16.2±10.5。与住院患者(16.9±10.2)相比,居家隔离的COVID患者的总污名评分更高(17±10.3)。结论:新冠肺炎患者污名水平的增加具有各种重要的心理社会影响。这项研究强调需要进行更大规模的前瞻性队列研究,以进一步了解新冠肺炎背景下的污名。
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引用次数: 2
Correlation of factors associated with marital satisfaction-A cross-sectional study from an urban place in Andhra Pradesh 与婚姻满意度相关因素的相关性——来自安得拉邦城市地区的横断面研究
Q4 Psychology Pub Date : 2022-07-01 DOI: 10.4103/amh.amh_146_21
S. Goud, Adavi Swayntika, Vishal Indla, N. Kolli
Context: Marriage is an age-old tradition that has become an essential custom for the survival and evolution of human beings. Marital satisfaction is the most essential aspect of a marriage. It is an important psychological construct affecting individual and relational well-being. Multiple factors affect marital satisfaction, and research related to these factors is scarce in India. Aims: We aimed to study the association between various sociodemographic factors, attachment styles, sexual satisfaction, and marital satisfaction. Materials and Methods: It was a cross-sectional, correlational study done on 80 subjects who were selected by purposive sampling method. A semi-structured pro forma was used to collect sociodemographic data. ENRICH (Evaluation and Nurturing Relationship Issues, Communication, and Happiness Marital Satisfaction scale was used to assess marital satisfaction. Index of Sexual Satisfaction was used for rating sexual satisfaction. A relationship questionnaire was used to measure the adult attachment style. Descriptive and inferential statistical analyses were done to find the relation between different study variables. Results: Among sociodemographic variables, gender (P = 0.03), ongoing conflicts (P < 0.001), and the attachment style of the subjects (P < 0.001) had shown a statistically significant relationship with marital satisfaction. Problems in the area of sexual satisfaction had a negative correlation with marital satisfaction (r = −663, P < 0.001). Conclusions: Although marital satisfaction is culturally dependent, attachment styles, ongoing conflicts in one's relationship, and sexual satisfaction are some of the common factors associated with marital satisfaction across cultures.
背景:婚姻是一项古老的传统,已经成为人类生存和进化的基本习俗。婚姻满意度是婚姻最重要的方面。它是影响个体和关系幸福感的重要心理构念。影响婚姻满意度的因素多种多样,在印度对这些因素的研究较少。目的:研究不同社会人口学因素、依恋类型、性满意度和婚姻满意度之间的关系。材料与方法:采用目的抽样法,对80名被试进行横断面相关性研究。采用半结构化的形式来收集社会人口统计数据。采用婚姻满意度量表评估婚姻满意度。采用性满意度指数评价性满意度。采用关系问卷对成人依恋类型进行测量。通过描述性和推断性统计分析来发现不同研究变量之间的关系。结果:在社会人口学变量中,性别(P = 0.03)、持续冲突(P < 0.001)和依恋类型(P < 0.001)对婚姻满意度有显著的影响。性满意度方面的问题与婚姻满意度呈负相关(r = - 663, P < 0.001)。结论:尽管婚姻满意度是文化依赖的,但依恋类型、关系中的持续冲突和性满意度是跨文化婚姻满意度的一些共同因素。
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引用次数: 0
Disability associated with premenstrual dysphoric disorder: A prospective study 残疾与经前烦躁障碍的相关性:一项前瞻性研究
Q4 Psychology Pub Date : 2022-07-01 DOI: 10.4103/amh.amh_110_22
Anusha Nemani, S. Kampalli, Nooka Nadukuru
Introduction: Premenstrual dysphoric disorder (PMDD), a severe form of premenstrual syndrome (PMS), is a of emotional, behavioral, and physical symptoms that cause severe functional impairment. This prospective, observational study was performed on students to assess the prevalence, the factors associated with PMS and PMDD, and the functional impairment caused by PMDD in various aspects of life. Methodology: The present study was conducted on 224 consenting college students who attained menarche using standardized instruments such as the Daily Record of Severity of Problems, the Carolina Premenstrual Assessment Scoring System, and the Sheehan Disability Scale. Results: The prevalence of PMS and PMDD was 19.64% and 4.46%, respectively. disability scores and functional impairment in the study were comparable to other major mental illnesses. Conclusion: This study therefore emphasizes the need for identification and prompt management of PMS and PMDD so as to improve the quality of life.
经前烦躁障碍(PMDD)是经前综合征(PMS)的一种严重形式,是一种情绪、行为和身体症状,可导致严重的功能障碍。这项前瞻性的观察性研究对学生进行了评估患病率,与经前症候群和经前不悦症相关的因素,以及经前不悦症在生活各方面引起的功能障碍。方法:本研究采用标准化的工具,如问题严重程度每日记录、卡罗莱纳经前评估评分系统和希恩残疾量表,对224名同意初潮的大学生进行了研究。结果:经前综合症和经前不悦症的患病率分别为19.64%和4.46%。研究中的残疾得分和功能损伤与其他主要精神疾病相当。结论:本研究强调了对经前综合征和经前不悦症的识别和及时治疗的必要性,以提高患者的生活质量。
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引用次数: 0
Lower serum ferritin levels and higher inattentiveness in attention deficit hyperactivity disorder in a case–control study 一项病例对照研究中注意缺陷多动障碍患者血清铁蛋白水平较低和注意力不集中程度较高
Q4 Psychology Pub Date : 2022-07-01 DOI: 10.4103/amh.amh_19_22
B. Anand, Chemarthi Sireesha
Introduction: Attention deficit hyperactivity disorder (ADHD) has hyperactivity, impulsivity, and inattentiveness. Brain iron stores influence dopamine synthesis and behavior. Serum ferritin is a marker for iron stores. Few studies are there on serum ferritin levels in ADHD, and the results showed either way as low or equal to controls. Contradictory results were observed in two published Indian studies, hence the need for the study. Aims and Objectives: The objectives of this study were to compare serum ferritin and hematological indexes between children with ADHD and normal controls and also to compare ADHD subscales in two of ADHD groups divided on a cutoff serum value of below 15 ng/ml (World Health Organization criteria). Materials and Methods: Children with ADHD without comorbidities were compared with controls at a child and adolescent psychiatry unit, Hyderabad, India, after ethics committee approval. The assessments included Conners' Parent Rating Scale (CPRS)-Revised (S), serum ferritin, and hematological indexes. Results: Two-three children with ADHD and 38 normal children as controls participated. The mean (standard deviation [SD]) of serum ferritin levels in the ADHD group 28.26 (16.46) and controls 23.06 (18.88) was not statistically significant. Significantly higher mean values (14.60) on cognitive/inattention subscale was noticed In below (15 ng/ml) serum ferritin level group compared to the mean (11.50) in above (15 ng/ml) serum ferritin group. Negative nonsignificant correlation (r = −0.366) between cognitive-inattention subscale of ADHD and serum ferritin levels was noticed. Conclusions: Iron-deficiency state showed higher inattentiveness on CPRS subscale than noniron-deficiency state. There is a weak negative correlation between serum ferritin and inattentiveness.
注意缺陷多动障碍(ADHD)表现为多动、冲动和注意力不集中。脑铁储存影响多巴胺的合成和行为。血清铁蛋白是铁储备的标志。很少有关于ADHD患者血清铁蛋白水平的研究,结果显示两者都低于或等于对照组。在印度发表的两项研究中观察到相互矛盾的结果,因此需要进行这项研究。目的和目的:本研究的目的是比较ADHD儿童和正常对照之间的血清铁蛋白和血液学指标,并比较两个ADHD组中以低于15 ng/ml(世界卫生组织标准)的血清临界值划分的ADHD亚量表。材料和方法:经伦理委员会批准,在印度海德拉巴的儿童和青少年精神病学部门,将无合并症的ADHD儿童与对照组进行比较。评估包括康纳斯父母评定量表(CPRS -修订版)、血清铁蛋白和血液学指标。结果:2 - 3名ADHD儿童和38名正常儿童作为对照。ADHD组血清铁蛋白水平均值28.26(16.46),对照组23.06(18.88),差异无统计学意义(标准差[SD])。血清铁蛋白水平低于(15 ng/ml)组的认知/注意力不集中量表平均值(14.60)显著高于高于(15 ng/ml)组的平均值(11.50)。ADHD认知不注意分量表与血清铁蛋白水平呈显著负相关(r = - 0.366)。结论:缺铁状态在CPRS量表上的注意力不集中程度高于非缺铁状态。血清铁蛋白与注意力不集中呈弱负相关。
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引用次数: 0
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Archives of Mental Health
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