S. Isa, A. Norliana JA, Ismaliza I, A. Yusof, R. Hami
Objective: Information regarding the level of chronic kidney disease (CKD) knowledge and its associated factors among high-risk patients is crucial for the planning of CKD prevention strategies. This study aimed to determine the level of CKD knowledge and its associated factors among patients with a recent diagnosis of diabetes mellitus (DM) attending follow-ups at a primary healthcare clinic in Penang. Material and Methods: This cross-sectional study involved the consecutive sampling of 100 recently diagnosed DM patients (within 5 years) attending diabetic follow-up at the Kepala Batas Health Clinic. The level of CKD knowledge was assessed using a self-administered validated questionnaire. Demographic characteristics were described using frequencies, percentages, means and standard deviations. Associated factors of CKD knowledge were determined using multiple logistic regression analysis. The level of statistical significance was set at p-value<0.05. Results: As high as 81.0% of the participants scored less than four out of seven marks for CKD knowledge. The mean score was 2.61, while the median score was 3.0. Educational level was identified as the single determinant of CKD knowledge among the study participants.Conclusion: In this study, patients with a recent diagnosis of DM attending follow-up in primary healthcare showed a poor level of CKD knowledge. To ensure the success of the CKD prevention programme among high-risk groups, healthcare providers must provide relevant and effective education to all diabetic patients in the early phase after DM diagnosis; particularly among those with a lower education background.
{"title":"CKD Knowledge and Its Associated Factors Among Patients with Type 2 Diabetes Mellitus Attending Follow-up in a Penang Primary Health Clinic","authors":"S. Isa, A. Norliana JA, Ismaliza I, A. Yusof, R. Hami","doi":"10.31584/jhsmr.2023981","DOIUrl":"https://doi.org/10.31584/jhsmr.2023981","url":null,"abstract":"Objective: Information regarding the level of chronic kidney disease (CKD) knowledge and its associated factors among high-risk patients is crucial for the planning of CKD prevention strategies. This study aimed to determine the level of CKD knowledge and its associated factors among patients with a recent diagnosis of diabetes mellitus (DM) attending follow-ups at a primary healthcare clinic in Penang. Material and Methods: This cross-sectional study involved the consecutive sampling of 100 recently diagnosed DM patients (within 5 years) attending diabetic follow-up at the Kepala Batas Health Clinic. The level of CKD knowledge was assessed using a self-administered validated questionnaire. Demographic characteristics were described using frequencies, percentages, means and standard deviations. Associated factors of CKD knowledge were determined using multiple logistic regression analysis. The level of statistical significance was set at p-value<0.05. Results: As high as 81.0% of the participants scored less than four out of seven marks for CKD knowledge. The mean score was 2.61, while the median score was 3.0. Educational level was identified as the single determinant of CKD knowledge among the study participants.Conclusion: In this study, patients with a recent diagnosis of DM attending follow-up in primary healthcare showed a poor level of CKD knowledge. To ensure the success of the CKD prevention programme among high-risk groups, healthcare providers must provide relevant and effective education to all diabetic patients in the early phase after DM diagnosis; particularly among those with a lower education background. ","PeriodicalId":36211,"journal":{"name":"Journal of Health Science and Medical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41602557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Taemkaew, C. Churungsuk, K. Khanungwanitkul, W. Keeratichananont, P. Tanutit, T. Liabsuetrakul
Objective: Lung cancer is the leading cause of cancer-related deaths. Although, previous research have shown that patients with non-small-cell lung cancer (NSCLC), with a higher body mass index (BMI), have a lower risk of death, only a few studies have examined the effects of body composition. Hence, this study examined the prognostic value of skeletal muscle mass and fat mass in patients with non-metastatic NSCLC. Material and Methods: This was a retrospective cohort study; from 2008 to 2012. Eighty-eight of 130 non-metastatic NSCLC patients underwent computed tomography to assess paravertebral skeletal muscle, subcutaneous adipose tissue (SAT), and visceral adipose-tissue (VAT) at the 3rd lumbar vertebral level. Spearman correlation analysis was used to analyze body-composition correlations. Cox regression analysis was used to determine prognostic markers. Results: Higher SAT and VAT indices were associated with a higher-survival probability (HR, 0.79; p-value=0.001 and, HR 0.88; p-value=0.016, respectively). In contrast, higher SAT density and VAT/SAT ratio were associated with a lower survival probability (HR 1.16, p-value=0.012; HR 1.28, p-value=0.006, respectively). Lower performance status and TNM stage 3 were associated with lower-survival probability (HR 2.60; p-value=0.004, HR 1.92; p-value=0.035, respectively).Conclusion: The VAT index predicts a better prognosis for patients with non-metastatic lung cancer; however, visceral-fat distribution, as measured by a high VAT/SAT ratio, is associated with a worse prognosis.
{"title":"Body Composition as Prognostic Markers for Survival of Patients with Non-Metastatic Non-Small-Cell Lung Cancer","authors":"K. Taemkaew, C. Churungsuk, K. Khanungwanitkul, W. Keeratichananont, P. Tanutit, T. Liabsuetrakul","doi":"10.31584/jhsmr.2023980","DOIUrl":"https://doi.org/10.31584/jhsmr.2023980","url":null,"abstract":"Objective: Lung cancer is the leading cause of cancer-related deaths. Although, previous research have shown that patients with non-small-cell lung cancer (NSCLC), with a higher body mass index (BMI), have a lower risk of death, only a few studies have examined the effects of body composition. Hence, this study examined the prognostic value of skeletal muscle mass and fat mass in patients with non-metastatic NSCLC. Material and Methods: This was a retrospective cohort study; from 2008 to 2012. Eighty-eight of 130 non-metastatic NSCLC patients underwent computed tomography to assess paravertebral skeletal muscle, subcutaneous adipose tissue (SAT), and visceral adipose-tissue (VAT) at the 3rd lumbar vertebral level. Spearman correlation analysis was used to analyze body-composition correlations. Cox regression analysis was used to determine prognostic markers. Results: Higher SAT and VAT indices were associated with a higher-survival probability (HR, 0.79; p-value=0.001 and, HR 0.88; p-value=0.016, respectively). In contrast, higher SAT density and VAT/SAT ratio were associated with a lower survival probability (HR 1.16, p-value=0.012; HR 1.28, p-value=0.006, respectively). Lower performance status and TNM stage 3 were associated with lower-survival probability (HR 2.60; p-value=0.004, HR 1.92; p-value=0.035, respectively).Conclusion: The VAT index predicts a better prognosis for patients with non-metastatic lung cancer; however, visceral-fat distribution, as measured by a high VAT/SAT ratio, is associated with a worse prognosis.","PeriodicalId":36211,"journal":{"name":"Journal of Health Science and Medical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45608117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wiyakarn Sanghuachang, Pornpat Hengudomsub, Nujjaree Chaimongkol, N. Kotchabhakdi
Objective: To explore the feasibility of neurobic exercise intervention among older adults with mild cognitive impairment (MCI). Material and Methods: This pilot study used a two-group pre-post test, with a follow-up design. Older adults with MCI were randomly assigned to the intervention group (n=10) or the control group (n=10). Measurements included: the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) and the Common Objects Memory Test (COMT). Acceptability was assessed using a satisfaction and helpfulness rating scale and open-ended questions. Results: The intervention group had a significant reduction in IQCODE relative change score, indicating improvement in cognitive decline, and had a significantly higher COMT relative change score, indicating improvement in cognitive performance at 3 and 6 weeks. Participants reported high satisfaction with the overall activities, and rated the intervention helpful. Conclusion: The neurobic exercise intervention was feasible and acceptable for Thai community-dwelling older adults.
{"title":"Feasibility Testing of Neurobic Exercise Intervention in Older Adults with Mild Cognitive Impairment","authors":"Wiyakarn Sanghuachang, Pornpat Hengudomsub, Nujjaree Chaimongkol, N. Kotchabhakdi","doi":"10.31584/jhsmr.2023979","DOIUrl":"https://doi.org/10.31584/jhsmr.2023979","url":null,"abstract":"Objective: To explore the feasibility of neurobic exercise intervention among older adults with mild cognitive impairment (MCI). Material and Methods: This pilot study used a two-group pre-post test, with a follow-up design. Older adults with MCI were randomly assigned to the intervention group (n=10) or the control group (n=10). Measurements included: the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) and the Common Objects Memory Test (COMT). Acceptability was assessed using a satisfaction and helpfulness rating scale and open-ended questions. Results: The intervention group had a significant reduction in IQCODE relative change score, indicating improvement in cognitive decline, and had a significantly higher COMT relative change score, indicating improvement in cognitive performance at 3 and 6 weeks. Participants reported high satisfaction with the overall activities, and rated the intervention helpful. Conclusion: The neurobic exercise intervention was feasible and acceptable for Thai community-dwelling older adults.","PeriodicalId":36211,"journal":{"name":"Journal of Health Science and Medical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45511397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: To analyze and compare the effects of Vibrapole exercises and elastic band exercises on abdominal strength in young healthy individuals. Material and Methods: In this experimental study, 80 healthy, young individuals between the age groups of 18-24 were screened and recruited and then allocated into 2 groups. Group A- abdominal strengthening exercise using vibrapole (n= 40) and Group B- abdominal strengthening exercise using an elastic band (n=40). The intervention was administered for 3 days/week, for 4 weeks to both groups. Progression was adjusted after 2 weeks, by increasing repetitions of exercises from 10 to 20. Outcome measures, including: surface Electromyography (EMG), pressure biofeedback and 7 stage sit-up test, were assessed pre and post-intervention. The analysis was performed with a 95% confidence interval. Results: Group A and B showed significant improvement (p-value<0.001) when analyzed individually for surface EMG, pressure biofeedback and 7-stage sit-up test. Group A showed more improvement in abdominal strength than group B in surface EMG (Mean Difference–Group A: 159.27+48.84 and Group B 126.32+39.96) and in 7-stage sit-up test (Mean Difference–Group A: 2.12+0.64 and Group B 1.67+0.57) as p-value<0.01. Pressure Biofeedback showed non-significant differences among the groups (p-value=0.2201). Conclusion: This study concludes that strengthening exercises using Vibrapole was more effective in increasing abdominal muscle strength than elastic band exercises. Hence Vibrapole can be used by physiotherapists as an effective tool to improve abdominal strength.
{"title":"Efficacy of Vibrapole Abdominal Strengthening Exercises on Strength in Healthy Young Individuals: An Experimental Study","authors":"Manisha Rathi, Preeti Gazbare, Nirali Ruparel","doi":"10.31584/jhsmr.2023977","DOIUrl":"https://doi.org/10.31584/jhsmr.2023977","url":null,"abstract":"Objective: To analyze and compare the effects of Vibrapole exercises and elastic band exercises on abdominal strength in young healthy individuals. Material and Methods: In this experimental study, 80 healthy, young individuals between the age groups of 18-24 were screened and recruited and then allocated into 2 groups. Group A- abdominal strengthening exercise using vibrapole (n= 40) and Group B- abdominal strengthening exercise using an elastic band (n=40). The intervention was administered for 3 days/week, for 4 weeks to both groups. Progression was adjusted after 2 weeks, by increasing repetitions of exercises from 10 to 20. Outcome measures, including: surface Electromyography (EMG), pressure biofeedback and 7 stage sit-up test, were assessed pre and post-intervention. The analysis was performed with a 95% confidence interval. Results: Group A and B showed significant improvement (p-value<0.001) when analyzed individually for surface EMG, pressure biofeedback and 7-stage sit-up test. Group A showed more improvement in abdominal strength than group B in surface EMG (Mean Difference–Group A: 159.27+48.84 and Group B 126.32+39.96) and in 7-stage sit-up test (Mean Difference–Group A: 2.12+0.64 and Group B 1.67+0.57) as p-value<0.01. Pressure Biofeedback showed non-significant differences among the groups (p-value=0.2201). Conclusion: This study concludes that strengthening exercises using Vibrapole was more effective in increasing abdominal muscle strength than elastic band exercises. Hence Vibrapole can be used by physiotherapists as an effective tool to improve abdominal strength.","PeriodicalId":36211,"journal":{"name":"Journal of Health Science and Medical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48048750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: To determine the effect of immediate skin-to-skin contact (SSC) between mothers and their newborns on episiotomy pain.Material and Methods: This randomized controlled trial enrolled 60 participants who underwent vaginal delivery. The participants were divided into two groups: an immediate SSC group and a no SSC group (n=30 for each group). SSC was initiated within 10 minutes after birth with a contact duration of at least 30 minutes. Episiotomy pain severity was evaluated using a visual analog scale (VAS) at one hour after birth in both groups. The pain scores were analyzed using the Mann-Whitney U test and the optimum contact time for reducing episiotomy wound pain was evaluated by a receiver operating characteristic (ROC) curve.Results: The median VAS of episiotomy pain at one hour after delivery in the SSC group was statistically significantly lower than the no SSC group (1.9 (0.8-3.1) vs. 3.4 (2-5.2) cm, p-value<0.001). The contact time for optimal pain reduction was at least 30 minutes of SSC.Conclusion: Immediate SSC contact between a mother and her neonate after delivery can effectively reduce episiotomy pain.
{"title":"Effect of Immediate Postpartum Skin-to-Skin Contact Between Mothers and Newborns on Episiotomy Pain: A Randomized Controlled Trial","authors":"Chanikan Taechavichitpisal, Nopporn Rodpenpear","doi":"10.31584/jhsmr.2023978","DOIUrl":"https://doi.org/10.31584/jhsmr.2023978","url":null,"abstract":"Objective: To determine the effect of immediate skin-to-skin contact (SSC) between mothers and their newborns on episiotomy pain.Material and Methods: This randomized controlled trial enrolled 60 participants who underwent vaginal delivery. The participants were divided into two groups: an immediate SSC group and a no SSC group (n=30 for each group). SSC was initiated within 10 minutes after birth with a contact duration of at least 30 minutes. Episiotomy pain severity was evaluated using a visual analog scale (VAS) at one hour after birth in both groups. The pain scores were analyzed using the Mann-Whitney U test and the optimum contact time for reducing episiotomy wound pain was evaluated by a receiver operating characteristic (ROC) curve.Results: The median VAS of episiotomy pain at one hour after delivery in the SSC group was statistically significantly lower than the no SSC group (1.9 (0.8-3.1) vs. 3.4 (2-5.2) cm, p-value<0.001). The contact time for optimal pain reduction was at least 30 minutes of SSC.Conclusion: Immediate SSC contact between a mother and her neonate after delivery can effectively reduce episiotomy pain.","PeriodicalId":36211,"journal":{"name":"Journal of Health Science and Medical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45766588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kittisak Agsornwong, T. Morasert, Kornkrit Limsommut, Phongsak Nitikaroon, Osaree Akaraborworn, Jintana Srisompong, Direk Deesiri, Kavalin Chuencharoensuk, Kanchanat Sangnak, N. Chierakul, S. Iamsirithaworn
Objective: During the third and fourth wave of the coronavirus disease 2019 (COVID-19); from April to September 2021 all hospitals in Bangkok Metropolitan Region reached surge capacity. Hence, Bussarakham Field Hospital (BH) was established to address this crisis. This study aimed to identify factors associated with in-hospital mortality in BH, Thailand’s largest field hospital for COVID-19. Material and Methods: This was a retrospective study among all adult COVID-19 patients, confirmed by Reverse transcription-polymerase chain reaction (RT-PCR), admitted to BH from May to September 2021. The data on potential factors associated with treatment outcome (survived or deceased) were retrieved from the standard admission records for COVID-19 and discharge summaries. A multivariable logistic regression model was performed to explore factors associated with in-hospital mortality. Results: A total of 18,173 patients were enrolled with death occurring in 224 patients during hospitalization. The mortality rate was 1.23%. The adjusted odds ratios (95% CIs) of male gender, aged >65 years, having diabetes mellitus, pregnancy, lower respiratory tract (LRT) symptoms at initial presentation, pneumonia with hypoxemia at initial presentation were: 1.91 (1.35, 2.70), 5.37 (3.75, 7.69), 2.55 (1.75, 3.71), 6.40 (2.15, 19.08), 2.81 (1.88, 4.19) and 3.11 (1.35, 7.15) respectively. Conclusion: The pre-existing factors that increased mortality risk consisted of elderly age, diabetes mellitus and pregnancy. In addition, patients who presented with LRT symptoms or pneumonia with hypoxemia also had a higher mortality risk. Therefore, clinical triage should be carefully performed in field hospitals during any pandemic.
{"title":"Clinical Characteristics and Factors Associated with Mortality of Patients with COVID-19 at Bussarakham Field Hospital: Thailand","authors":"Kittisak Agsornwong, T. Morasert, Kornkrit Limsommut, Phongsak Nitikaroon, Osaree Akaraborworn, Jintana Srisompong, Direk Deesiri, Kavalin Chuencharoensuk, Kanchanat Sangnak, N. Chierakul, S. Iamsirithaworn","doi":"10.31584/jhsmr.2023975","DOIUrl":"https://doi.org/10.31584/jhsmr.2023975","url":null,"abstract":"Objective: During the third and fourth wave of the coronavirus disease 2019 (COVID-19); from April to September 2021 all hospitals in Bangkok Metropolitan Region reached surge capacity. Hence, Bussarakham Field Hospital (BH) was established to address this crisis. This study aimed to identify factors associated with in-hospital mortality in BH, Thailand’s largest field hospital for COVID-19. Material and Methods: This was a retrospective study among all adult COVID-19 patients, confirmed by Reverse transcription-polymerase chain reaction (RT-PCR), admitted to BH from May to September 2021. The data on potential factors associated with treatment outcome (survived or deceased) were retrieved from the standard admission records for COVID-19 and discharge summaries. A multivariable logistic regression model was performed to explore factors associated with in-hospital mortality. Results: A total of 18,173 patients were enrolled with death occurring in 224 patients during hospitalization. The mortality rate was 1.23%. The adjusted odds ratios (95% CIs) of male gender, aged >65 years, having diabetes mellitus, pregnancy, lower respiratory tract (LRT) symptoms at initial presentation, pneumonia with hypoxemia at initial presentation were: 1.91 (1.35, 2.70), 5.37 (3.75, 7.69), 2.55 (1.75, 3.71), 6.40 (2.15, 19.08), 2.81 (1.88, 4.19) and 3.11 (1.35, 7.15) respectively. Conclusion: The pre-existing factors that increased mortality risk consisted of elderly age, diabetes mellitus and pregnancy. In addition, patients who presented with LRT symptoms or pneumonia with hypoxemia also had a higher mortality risk. Therefore, clinical triage should be carefully performed in field hospitals during any pandemic.","PeriodicalId":36211,"journal":{"name":"Journal of Health Science and Medical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45723069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Waratsuda Samuthtai, J. Patumanond, Pawitrabhorn Samuthtai, T. Charernboon, Kijja Jearwattanakanok, J. Khorana
Objective: A prediction model: "TERMINAL-24,” was developed and internally validated for use in predicting early mortality of multiple trauma patients in the Emergency Department. In this study this model's external validity and generalizability was evaluated.Material and Methods: A retrospective cohort was used for the construction of two datasets. Temporal external validation used the dataset from the same location at a different period, and geographic external validation used the dataset from a different location.Results: In total, 1,932 patients underwent temporal external validation, with 14 (0.7%) patients dyeing within 8 hours, 35 (1.8%) patients died between 8 and 24 hours, and 1,883(97.5%) patients were alive at 24 hours. From this, 2,336 patients were eligible for geographical external validation, with 106 (4.5%) patients having died at the emergency room, 143 (6.1%) patients died in hospital and 2,087 (89.3%) patients survived. The TERMINAL-24 score was applied to both datasets, with a benchmark of 4 or higher (range 0-5). In the temporal dataset, this score showed a mortality of greater than 20% (specificity 0.97) area under the receiver operating characteristic curve (AuROC) 0.91 (95% Confidence interval (CI) 0.85-0.96); whereas, it demonstrated a mortality of greater than 60% (specificity 0.99) AuROC 0.92 (95%CI 0.89-0.94) in the geographical dataset.Conclusion: TERMINAL-24 was effective at predicting early death in the emergency room. It was successfully implemented within the same hospital; hoever, the cut-point should be adapted for application in other institutions with unspecified time of death. Prospective studies at different hospitals should be planned to generalize this scoring system for clinical practice.
{"title":"External Validation of the TERMINAL-24 Score in Predicting Mortality in Patients with Multiple Trauma","authors":"Waratsuda Samuthtai, J. Patumanond, Pawitrabhorn Samuthtai, T. Charernboon, Kijja Jearwattanakanok, J. Khorana","doi":"10.31584/jhsmr.2023974","DOIUrl":"https://doi.org/10.31584/jhsmr.2023974","url":null,"abstract":"Objective: A prediction model: \"TERMINAL-24,” was developed and internally validated for use in predicting early mortality of multiple trauma patients in the Emergency Department. In this study this model's external validity and generalizability was evaluated.Material and Methods: A retrospective cohort was used for the construction of two datasets. Temporal external validation used the dataset from the same location at a different period, and geographic external validation used the dataset from a different location.Results: In total, 1,932 patients underwent temporal external validation, with 14 (0.7%) patients dyeing within 8 hours, 35 (1.8%) patients died between 8 and 24 hours, and 1,883(97.5%) patients were alive at 24 hours. From this, 2,336 patients were eligible for geographical external validation, with 106 (4.5%) patients having died at the emergency room, 143 (6.1%) patients died in hospital and 2,087 (89.3%) patients survived. The TERMINAL-24 score was applied to both datasets, with a benchmark of 4 or higher (range 0-5). In the temporal dataset, this score showed a mortality of greater than 20% (specificity 0.97) area under the receiver operating characteristic curve (AuROC) 0.91 (95% Confidence interval (CI) 0.85-0.96); whereas, it demonstrated a mortality of greater than 60% (specificity 0.99) AuROC 0.92 (95%CI 0.89-0.94) in the geographical dataset.Conclusion: TERMINAL-24 was effective at predicting early death in the emergency room. It was successfully implemented within the same hospital; hoever, the cut-point should be adapted for application in other institutions with unspecified time of death. Prospective studies at different hospitals should be planned to generalize this scoring system for clinical practice.","PeriodicalId":36211,"journal":{"name":"Journal of Health Science and Medical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41362780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: According to World Health Organization (WHO) recommendations, vaccination can save millions of lives,and it is widely known as one of the most successful and cost-effective health interventions. Nevertheless, some peopleare reluctant to be vaccinated because of potential side effects. This study aimed to analyze the effects of knowledge,attitudes, and behavior related to the coronavirus disease 2019 (COVID-19) vaccine acceptance.Material and Methods: This is a quantitative study that employed the cross-sectional approach and was conducted from December 2021 to February 2022. Data were collected from 520 samples aged 22-64 years chosen via simple random sampling. The data collection was carried out using a questionnaire via Google Forms. To analyze the acceptance of the COVID-19 vaccination program in the community, multiple linear regressions using the SPSS software version 25 were employed.Results: Knowledge (b=0.11, SE=0.05, 95% CI=0.01 to 0.21, p-value=0.030), attitude (b=0.08, SE=0.03, 95% CI=0.03 to 0.13, p-value=0.003), and behavior (b=0.07, SE=0.02, 95% CI=0.03 to 0.10, p-value<0.001) affected the COVID-19 vaccine acceptance. The higher the knowledge about the COVID-19 vaccine, the higher the public acceptance of the vaccination program. Likewise, the more positive the public’s attitude towards the COVID-19 vaccine, the higher its acceptance of the vaccination. The better the public’s behavior related to COVID-19 vaccination, the higher the level of acceptance of the COVID-19 vaccine.Conclusion: Comprehensive knowledge, positive attitudes, and good behavior related to the COVID-19 vaccinationaffect the acceptance of COVID-19 vaccine by the public of Indonesia. Even when people have received a completeCOVID-19 vaccination, they should remain disciplined in implementing the recommended health protocols of the relevant institutions and organizations.
{"title":"Knowledge, Attitude, and Behavior Related to COVID-19 Vaccine Acceptance: A Cross-Sectional Study","authors":"Reny Nugraheni, Wahyu Sri Astutik","doi":"10.31584/jhsmr.2023973","DOIUrl":"https://doi.org/10.31584/jhsmr.2023973","url":null,"abstract":"Objective: According to World Health Organization (WHO) recommendations, vaccination can save millions of lives,and it is widely known as one of the most successful and cost-effective health interventions. Nevertheless, some peopleare reluctant to be vaccinated because of potential side effects. This study aimed to analyze the effects of knowledge,attitudes, and behavior related to the coronavirus disease 2019 (COVID-19) vaccine acceptance.Material and Methods: This is a quantitative study that employed the cross-sectional approach and was conducted from December 2021 to February 2022. Data were collected from 520 samples aged 22-64 years chosen via simple random sampling. The data collection was carried out using a questionnaire via Google Forms. To analyze the acceptance of the COVID-19 vaccination program in the community, multiple linear regressions using the SPSS software version 25 were employed.Results: Knowledge (b=0.11, SE=0.05, 95% CI=0.01 to 0.21, p-value=0.030), attitude (b=0.08, SE=0.03, 95% CI=0.03 to 0.13, p-value=0.003), and behavior (b=0.07, SE=0.02, 95% CI=0.03 to 0.10, p-value<0.001) affected the COVID-19 vaccine acceptance. The higher the knowledge about the COVID-19 vaccine, the higher the public acceptance of the vaccination program. Likewise, the more positive the public’s attitude towards the COVID-19 vaccine, the higher its acceptance of the vaccination. The better the public’s behavior related to COVID-19 vaccination, the higher the level of acceptance of the COVID-19 vaccine.Conclusion: Comprehensive knowledge, positive attitudes, and good behavior related to the COVID-19 vaccinationaffect the acceptance of COVID-19 vaccine by the public of Indonesia. Even when people have received a completeCOVID-19 vaccination, they should remain disciplined in implementing the recommended health protocols of the relevant institutions and organizations.","PeriodicalId":36211,"journal":{"name":"Journal of Health Science and Medical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49022095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: To assess the risk factors and Surgical Site Infections (SSI) in patients with surgical antibiotic prophylaxis (SAP) within the Indian population. Material and Methods: A prospective cohort study, consisting of 1,362 patients, with the age of 18 and above; admitted for various surgical procedures, and prescribed with SAP were included. In order to determine the significance of categorical data, the chi-square test, and Multiple binary logistic regression via the backward wald method was used to identify the risk factors. Various risk factors and their association to SSI were assessed, with a probability value of ≤0.05 being considered as a significant level. Result: In total, 171 SSI were observed; with an incidence of 12.6% [95% CI=11.1-16.6] among all study patients (1,362). Cefotaxime was the most prescribed SAP in this study. In total 59.6% had gram-positive organisms and 40.4% had gram-negative organisms. Type of surgery, female gender, smoking and alcohol, diabetes with hypertension, microbial growth, American Society of Anesthesiologists (ASA) score (class III), hospital guidelines, and pre-operative hospital stays (>7 days) were the significant risk factors (p-value<0.05) associated with SSI. There was no significant association with drain use, nor redosing (p-value>0.05). Conclusion: This study emphasizes the significant risk factors; such as age, female gender, types of surgery, ASA score, nonadherence to hospital guidelines, monomicrobial and polymicrobial growth and poor compliance to SAP being associated with SSI in surgical patients. These risk factors allow a better understanding related to SSI, which may have therapeutic implications.
{"title":"Risk Factors and Surgical Site Infection in Patients with Surgical Antibiotic Prophylaxis in the Indian Population: A Prospective Cohort Study","authors":"Karthik Sankar, Deepika Anbalagan, Balaswetha Baskaran, Vysali Segaran, Yogitha Prabakar, Sridhar Raghu, Vidhya Krishna, Venkatesan Singaram, Xavier Santhiyagu, M. Rajanandh","doi":"10.31584/jhsmr.2023971","DOIUrl":"https://doi.org/10.31584/jhsmr.2023971","url":null,"abstract":"Objective: To assess the risk factors and Surgical Site Infections (SSI) in patients with surgical antibiotic prophylaxis (SAP) within the Indian population. Material and Methods: A prospective cohort study, consisting of 1,362 patients, with the age of 18 and above; admitted for various surgical procedures, and prescribed with SAP were included. In order to determine the significance of categorical data, the chi-square test, and Multiple binary logistic regression via the backward wald method was used to identify the risk factors. Various risk factors and their association to SSI were assessed, with a probability value of ≤0.05 being considered as a significant level. Result: In total, 171 SSI were observed; with an incidence of 12.6% [95% CI=11.1-16.6] among all study patients (1,362). Cefotaxime was the most prescribed SAP in this study. In total 59.6% had gram-positive organisms and 40.4% had gram-negative organisms. Type of surgery, female gender, smoking and alcohol, diabetes with hypertension, microbial growth, American Society of Anesthesiologists (ASA) score (class III), hospital guidelines, and pre-operative hospital stays (>7 days) were the significant risk factors (p-value<0.05) associated with SSI. There was no significant association with drain use, nor redosing (p-value>0.05). Conclusion: This study emphasizes the significant risk factors; such as age, female gender, types of surgery, ASA score, nonadherence to hospital guidelines, monomicrobial and polymicrobial growth and poor compliance to SAP being associated with SSI in surgical patients. These risk factors allow a better understanding related to SSI, which may have therapeutic implications.","PeriodicalId":36211,"journal":{"name":"Journal of Health Science and Medical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43764963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yonten Jamisho, J. Pakpirom, Wisarut Srisintorn, T. Chanchayanon, Chanatthee Kitsiripant, Dararat Yongsata, Khantaros Saelim
Objective: To assess the factors associated with ineffective thoracic epidural analgesia (iTEA) in the post-anesthesia care unit (PACU) among patients requiring TEA. Material and Methods: This prospective cohort was conducted on 146 patients requiring post-operative TEA. The verbal numeric rating scale (VNRS) was employed to assess TEA effectiveness on PACU arrival at 10, 20, and 30 minutes after surgery; iTEA was determined if the VNRS score was more than 3 and 4 at rest and during activity, respectively. The patient characteristics, and intra- and post-operative epidural management were collected. The risk factors of iTEA were evaluated using mixed-effects models. Moreover, factors associated with severe pain at PACU discharge were evaluated using logistic regression analyses. Results: The incidence of iTEA on PACU arrival, and at 10, 20, and 30 minutes after PACU arrival were 53.4%, 51.4%, 50.7%, and 36.3%, respectively. Intra-operative intravenous morphine supplementation and the cumulative fentanyl equivalent dose (every 10 mcg) were significantly associated with preventing the risk of iTEA on PACU arrival (OR 0.27; 95% CI=0.07-0.92) and during PACU stay (OR 0.87; 95% CI=0.77-0.97) compared to those who did not receive opioids. Moreover, iTEA on PACU arrival was a significant risk for severe pain at 30 minutes (adjusted OR 4.77; 95% CI=1.57-18.10). Conclusion: This study demonstrates a high incidence of iTEA immediately after surgery, and that intravenous opioid supplementation during and after surgery reduces the risk of iTEA. Lastly, iTEA on PACU arrival is a strong predictor of severe pain at discharge from PACU.
{"title":"The Effectiveness of Intraoperative Thoracic Epidural Analgesia in Major Abdominal and Thoracic Surgery and Its Prediction of Severe Pain at Discharge from the Post-Anesthetic Care Unit: A Prospective Cohort Study","authors":"Yonten Jamisho, J. Pakpirom, Wisarut Srisintorn, T. Chanchayanon, Chanatthee Kitsiripant, Dararat Yongsata, Khantaros Saelim","doi":"10.31584/jhsmr.2023970","DOIUrl":"https://doi.org/10.31584/jhsmr.2023970","url":null,"abstract":"Objective: To assess the factors associated with ineffective thoracic epidural analgesia (iTEA) in the post-anesthesia care unit (PACU) among patients requiring TEA. Material and Methods: This prospective cohort was conducted on 146 patients requiring post-operative TEA. The verbal numeric rating scale (VNRS) was employed to assess TEA effectiveness on PACU arrival at 10, 20, and 30 minutes after surgery; iTEA was determined if the VNRS score was more than 3 and 4 at rest and during activity, respectively. The patient characteristics, and intra- and post-operative epidural management were collected. The risk factors of iTEA were evaluated using mixed-effects models. Moreover, factors associated with severe pain at PACU discharge were evaluated using logistic regression analyses. Results: The incidence of iTEA on PACU arrival, and at 10, 20, and 30 minutes after PACU arrival were 53.4%, 51.4%, 50.7%, and 36.3%, respectively. Intra-operative intravenous morphine supplementation and the cumulative fentanyl equivalent dose (every 10 mcg) were significantly associated with preventing the risk of iTEA on PACU arrival (OR 0.27; 95% CI=0.07-0.92) and during PACU stay (OR 0.87; 95% CI=0.77-0.97) compared to those who did not receive opioids. Moreover, iTEA on PACU arrival was a significant risk for severe pain at 30 minutes (adjusted OR 4.77; 95% CI=1.57-18.10). Conclusion: This study demonstrates a high incidence of iTEA immediately after surgery, and that intravenous opioid supplementation during and after surgery reduces the risk of iTEA. Lastly, iTEA on PACU arrival is a strong predictor of severe pain at discharge from PACU.","PeriodicalId":36211,"journal":{"name":"Journal of Health Science and Medical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48301054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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