Objective: To evaluate anaesthetic outcome, patient outcome and timing of perioperative antithrombotic therapy in relation to intrathecal injection in patients undergoing infrainguinal revascularisation surgery, for peripheral artery disease (PAD) in spinal anaesthesia.Material and Methods: A one-year prospective observational study was conducted; from May 2019 to May 2020, in a tertiary care centre. This included all consecutive patients undergoing infrainguinal revascularisation surgery for PAD under spinal anaesthesia. Preoperative antithrombotics were stopped, as per standard guidelines, to achieve a normal coagulation profile before spinal anaesthesia. Perioperative data related to the patients, antithrombotics, anaesthesia, surgery, and complications were recorded. Primary outcomes measured were anaesthetic outcome in terms of spinal success and spinal safety. Secondary outcomes measured were timing of perioperative antithrombotic therapy in relation to intrathecal injection and patient outcomes defined as: good, morbidity or mortality.Results: A total of 102 patients were evaluated, with a mean age of 54.69±16.36 years (91% males, 9% females): 58% had medical comorbidities. A single dose of intravenous (IV) unfractionated heparin (5,000-7,500 IU) was given intraoperatively at 24.97±3.69 minutes after intrathecal injection. Anaesthetic outcome was good in all patients; in terms of spinal safety (100%), as none of the patients developed spinal related complications. All had spinal success (100%), as no patient required conversion to general anaesthesia. Postoperatively, 98% (100) of patients had good outcomes, and mortality only occurred in 2% (2) of patients.Conclusion: Spinal anaesthesia is safe and effective for infrainguinal revascularisation surgery. If the patient has a normal preoperative coagulation profile, and the timeline to stop antithrombotic therapy is strictly followed, administration of IV unfractionated heparin (5,000-7,500 IU); at approximately 25 minutes after intrathecal injection, was found to be safe.
{"title":"Evaluation of Safety of Spinal Anaesthesia in Patients Receiving Perioperative Antithrombotic Therapy Undergoing Infrainguinal Revascularisation Surgeries: A One-Year Prospective Clinical Research","authors":"Udita Naithani, Anjuri Goyal, Surendra Kumar Sethi, R. Navaria, Riyaz Ahamed, Vandana Gakkhar","doi":"10.31584/jhsmr.20231021","DOIUrl":"https://doi.org/10.31584/jhsmr.20231021","url":null,"abstract":"Objective: To evaluate anaesthetic outcome, patient outcome and timing of perioperative antithrombotic therapy in relation to intrathecal injection in patients undergoing infrainguinal revascularisation surgery, for peripheral artery disease (PAD) in spinal anaesthesia.Material and Methods: A one-year prospective observational study was conducted; from May 2019 to May 2020, in a tertiary care centre. This included all consecutive patients undergoing infrainguinal revascularisation surgery for PAD under spinal anaesthesia. Preoperative antithrombotics were stopped, as per standard guidelines, to achieve a normal coagulation profile before spinal anaesthesia. Perioperative data related to the patients, antithrombotics, anaesthesia, surgery, and complications were recorded. Primary outcomes measured were anaesthetic outcome in terms of spinal success and spinal safety. Secondary outcomes measured were timing of perioperative antithrombotic therapy in relation to intrathecal injection and patient outcomes defined as: good, morbidity or mortality.Results: A total of 102 patients were evaluated, with a mean age of 54.69±16.36 years (91% males, 9% females): 58% had medical comorbidities. A single dose of intravenous (IV) unfractionated heparin (5,000-7,500 IU) was given intraoperatively at 24.97±3.69 minutes after intrathecal injection. Anaesthetic outcome was good in all patients; in terms of spinal safety (100%), as none of the patients developed spinal related complications. All had spinal success (100%), as no patient required conversion to general anaesthesia. Postoperatively, 98% (100) of patients had good outcomes, and mortality only occurred in 2% (2) of patients.Conclusion: Spinal anaesthesia is safe and effective for infrainguinal revascularisation surgery. If the patient has a normal preoperative coagulation profile, and the timeline to stop antithrombotic therapy is strictly followed, administration of IV unfractionated heparin (5,000-7,500 IU); at approximately 25 minutes after intrathecal injection, was found to be safe.","PeriodicalId":36211,"journal":{"name":"Journal of Health Science and Medical Research","volume":"24 52","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139156026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wainik Sookmee, T. Liabsuetrakul, Siriwimon Tantarattanapong, P. Wuthisuthimethawee
Objective: To assess the emergency department length of stay (EDLOS) and mortality in each Emergency Severity Index (ESI) triage level. In addition to identifying the cut-off point of EDLOS to predict 72-hour in-hospital mortality among adult non-traumatic patients in the ED of a university hospital.Material and Methods: A cross-sectional study was conducted by retrieving patient data from the hospital information system; from January 1, 2014, to December 31, 2018. Patient characteristics, EDLOS, and in-hospital mortality rates were analyzed using the R program. The cut-off values of EDLOS, via the area under the curve for the best prediction of 72-hour in-hospital mortality in patients at different ESI levels, were analyzed by multivariate analysis. Statistical significance was defined as a p-value of ≤0.05.Results: Data from 71,247 patients with 123,356 visits were enrolled. EDLOS significantly decreased across ESI levels and the in-hospital mortality rates were highest in ESI 1, followed by ESI 2 and ESI 3. The predictive ability of EDLOS was the highest for ESI 4, followed by ESI 3. The cut-off point of EDLOS at 3.58 hours showed the best sensitivity, which was a significant risk factor for mortality after adjusting for other significant variables. An EDLOS longer than 4 hours was a significant factor for poor survival in patients with ESI 2 and ESI 3.Conclusion: A practical cut-off point of 4 hours EDLOS can be used to predict 72-hour in-hospital mortality. Healthcare providers in the ED should consider EDLOS as a safety indicator for quality assurance.
目的：评估急诊科住院时间（EDLOS）和死亡率：评估每个急诊严重程度指数（ESI）分诊级别的急诊科住院时间（EDLOS）和死亡率。此外，确定 EDLOS 的临界点，以预测某大学附属医院急诊科非外伤性成人患者 72 小时院内死亡率：通过从医院信息系统中检索患者数据，开展了一项横断面研究；研究时间为 2014 年 1 月 1 日至 2018 年 12 月 31 日。使用 R 程序分析了患者特征、EDLOS 和院内死亡率。通过对不同ESI水平患者72小时院内死亡率的最佳预测曲线下面积，对EDLOS的临界值进行了多变量分析。统计显著性定义为 p 值≤0.05：结果：共收集了 71,247 名患者的数据，访问次数达 123,356 次。EDLOS 的预测能力在 ESI 4 中最高，其次是 ESI 3。EDLOS 的临界点为 3.58 小时，显示出最佳灵敏度，在调整其他重要变量后，它是死亡率的重要风险因素。EDLOS 超过 4 小时是导致 ESI 2 和 ESI 3 患者存活率低的重要因素：结论：EDLOS 4 小时这一实用的临界点可用于预测 72 小时的院内死亡率。急诊室的医护人员应将 EDLOS 作为保证质量的安全指标。
{"title":"Emergency Department Length of Stay and in-Hospital Mortality of Non-Traumatic Patients in a University Hospital","authors":"Wainik Sookmee, T. Liabsuetrakul, Siriwimon Tantarattanapong, P. Wuthisuthimethawee","doi":"10.31584/jhsmr.20231018","DOIUrl":"https://doi.org/10.31584/jhsmr.20231018","url":null,"abstract":"Objective: To assess the emergency department length of stay (EDLOS) and mortality in each Emergency Severity Index (ESI) triage level. In addition to identifying the cut-off point of EDLOS to predict 72-hour in-hospital mortality among adult non-traumatic patients in the ED of a university hospital.Material and Methods: A cross-sectional study was conducted by retrieving patient data from the hospital information system; from January 1, 2014, to December 31, 2018. Patient characteristics, EDLOS, and in-hospital mortality rates were analyzed using the R program. The cut-off values of EDLOS, via the area under the curve for the best prediction of 72-hour in-hospital mortality in patients at different ESI levels, were analyzed by multivariate analysis. Statistical significance was defined as a p-value of ≤0.05.Results: Data from 71,247 patients with 123,356 visits were enrolled. EDLOS significantly decreased across ESI levels and the in-hospital mortality rates were highest in ESI 1, followed by ESI 2 and ESI 3. The predictive ability of EDLOS was the highest for ESI 4, followed by ESI 3. The cut-off point of EDLOS at 3.58 hours showed the best sensitivity, which was a significant risk factor for mortality after adjusting for other significant variables. An EDLOS longer than 4 hours was a significant factor for poor survival in patients with ESI 2 and ESI 3.Conclusion: A practical cut-off point of 4 hours EDLOS can be used to predict 72-hour in-hospital mortality. Healthcare providers in the ED should consider EDLOS as a safety indicator for quality assurance.","PeriodicalId":36211,"journal":{"name":"Journal of Health Science and Medical Research","volume":"7 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139000170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kan Komany, Woranan Kirisattayakul, Napat Ritlumlert, Sutthirak Tangruangkiat, P. Pairodsantikul, Saiwaroon Teankuae, Supannika Kawvised
Objective: This study aimed to develop an in-house breast phantom, and assess students’ knowledge and satisfaction after using it for mammographic positioning training.Material and Methods: The breast phantom was designed in a half-body shape, and constructed primarily using gelcoat resin, polyurethane foam, and thermoreversible gel. Additionally, silicone type RA-210, known for its high flexibility, tensile strength, elongation at break (620%), and ability to revert to its original shape, was incorporated. This study evaluated the effectiveness of the breast phantom utility in improving students’ knowledge through a nine-item questionnaire; employing a one-group pre-post design. The participants, consisting of 63 Radiologic Technology students, whom rated their satisfaction with the phantom for training purposes using a five-point Likert scale.Results: The mean knowledge score for the breast phantom positioning significantly improved from 5.35±1.61 points (pretest) to 7.32±1.20 points (post-test), following training (p-value<0.001). The students expressed high overall satisfaction with this training aid (4.49±0.58 points).Conclusion: Our breast phantom demonstrates its potential as an effective educational tool that enhances Radiologic Technology students’ understanding of mammographic positioning. However, further research is warranted to develop more advanced phantoms and to explore alternative experimental designs for effective teaching methods.
{"title":"Effectiveness of a Developed In-House Breast Phantom in Enhancing the Knowledge of Mammographic Positioning in Radiologic Technology Students: A Quasi-Experimental Study in Thailand","authors":"Kan Komany, Woranan Kirisattayakul, Napat Ritlumlert, Sutthirak Tangruangkiat, P. Pairodsantikul, Saiwaroon Teankuae, Supannika Kawvised","doi":"10.31584/jhsmr.20231017","DOIUrl":"https://doi.org/10.31584/jhsmr.20231017","url":null,"abstract":"Objective: This study aimed to develop an in-house breast phantom, and assess students’ knowledge and satisfaction after using it for mammographic positioning training.Material and Methods: The breast phantom was designed in a half-body shape, and constructed primarily using gelcoat resin, polyurethane foam, and thermoreversible gel. Additionally, silicone type RA-210, known for its high flexibility, tensile strength, elongation at break (620%), and ability to revert to its original shape, was incorporated. This study evaluated the effectiveness of the breast phantom utility in improving students’ knowledge through a nine-item questionnaire; employing a one-group pre-post design. The participants, consisting of 63 Radiologic Technology students, whom rated their satisfaction with the phantom for training purposes using a five-point Likert scale.Results: The mean knowledge score for the breast phantom positioning significantly improved from 5.35±1.61 points (pretest) to 7.32±1.20 points (post-test), following training (p-value<0.001). The students expressed high overall satisfaction with this training aid (4.49±0.58 points).Conclusion: Our breast phantom demonstrates its potential as an effective educational tool that enhances Radiologic Technology students’ understanding of mammographic positioning. However, further research is warranted to develop more advanced phantoms and to explore alternative experimental designs for effective teaching methods. ","PeriodicalId":36211,"journal":{"name":"Journal of Health Science and Medical Research","volume":"7 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139000860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maneerat Puwanant, S. Jaruratanasirikul, Praenapa Chaithaweesup, Sasivara Boonrusmee, Kanjana Chimrung, H. Sriplung
Objective: To determine complementary food intake, food group diversity and nutritional adequacy of 6-12-month-old infants in southern Thailand.Material and Methods: A total of 120 healthy infants, aged 6-12 months, were enrolled: from December 2020 to November 2021. A 24-hour food record was used to assess the type, amount and frequency of food intake in each infant. The infants’ food intake was classified into seven food groups. Macronutrient and micronutrient intakes were analysed using the INMUCAL software program; the standard program for the calculation of nutrients in Thai food.Results: Of the 120 infants, 10 (8.3%) received breast and/or formula feeding without complementary food; 30 (25%) received 1, 66 (55%) received 2, and 14 (11.7%) 3-4 received complementary meals a day. The 4 most common supplementary foods given to the infants were rice mixed with vitamin A-rich fruits or vegetables, meat, eggs, or other fruits (mostly bananas). Infants who received 1 complementary meal, with 1-3 food groups a day, had significantly higher percentages of micronutrient inadequacies (iron, magnesium, selenium and vitamin E) than those receiving at least 2 complementary meals; with at least 4 food groups a day.Conclusion: Infants in southern Thailand who were fed <4 food groups with <2 complementary meals a day were at risk of micronutrient inadequacies; such as iron, magnesium, selenium and vitamin E. Therefore, infants aged 6-7 months should be given a minimum meal frequency (MMF) of 2 meals, with a minimum dietary diversity (MDD) of 4 food groups per day.
{"title":"Complementary Feeding: Food Group Diversity and Probability of Nutrient Adequacy among 6-12-Month-Old Infants in Southern Thailand","authors":"Maneerat Puwanant, S. Jaruratanasirikul, Praenapa Chaithaweesup, Sasivara Boonrusmee, Kanjana Chimrung, H. Sriplung","doi":"10.31584/jhsmr.20231016","DOIUrl":"https://doi.org/10.31584/jhsmr.20231016","url":null,"abstract":"Objective: To determine complementary food intake, food group diversity and nutritional adequacy of 6-12-month-old infants in southern Thailand.Material and Methods: A total of 120 healthy infants, aged 6-12 months, were enrolled: from December 2020 to November 2021. A 24-hour food record was used to assess the type, amount and frequency of food intake in each infant. The infants’ food intake was classified into seven food groups. Macronutrient and micronutrient intakes were analysed using the INMUCAL software program; the standard program for the calculation of nutrients in Thai food.Results: Of the 120 infants, 10 (8.3%) received breast and/or formula feeding without complementary food; 30 (25%) received 1, 66 (55%) received 2, and 14 (11.7%) 3-4 received complementary meals a day. The 4 most common supplementary foods given to the infants were rice mixed with vitamin A-rich fruits or vegetables, meat, eggs, or other fruits (mostly bananas). Infants who received 1 complementary meal, with 1-3 food groups a day, had significantly higher percentages of micronutrient inadequacies (iron, magnesium, selenium and vitamin E) than those receiving at least 2 complementary meals; with at least 4 food groups a day.Conclusion: Infants in southern Thailand who were fed <4 food groups with <2 complementary meals a day were at risk of micronutrient inadequacies; such as iron, magnesium, selenium and vitamin E. Therefore, infants aged 6-7 months should be given a minimum meal frequency (MMF) of 2 meals, with a minimum dietary diversity (MDD) of 4 food groups per day.","PeriodicalId":36211,"journal":{"name":"Journal of Health Science and Medical Research","volume":"18 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139003016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shanaya Phal Desai, Christine Kurian, Semanti Das, Stena Jesima Rebello, Sayanti Acharyya, K. Paari
Probiotics have emerged as a potential alternative for treating various diseases affecting general population. Mounting data suggests that probiotics can be beneficial for older individuals, who often have weakened immune systems and are more susceptible to illnesses. Dysbiosis commonly occurs in elderly individuals, which is implicated as a major reason for various diseases. The effectiveness of probiotics is influenced by the specific strain and the dosage administered. Extensive studies have shown how probiotics affect prevalent issues, such as functional bowel diseases and other gastrointestinal disorders. Probiotics exert their effects by synthesizing different microbial peptides, such as bacteriocins, antibiotics, lipopolysaccharides, short-chain fatty acids, butyric acid, propionic acid and other specific secretory metabolites. The common probiotics that are found to benefit the health of elderly populations include Lactobacillus, Bifidobacterium lactis, Bacillus subtilis, Bifidobacterium longum and Bifidobacterium breve Further research is necessary to delve into the mechanism of action for both existing and novel probiotic strains for use in combating or aiding in diseases. Genetically, modified probiotics can be potentially used in the future to deliver immunity-restoring genes and as oral mode of vaccination in humans. Fecal microbiota transplantation has been gaining interest, used to restore gut conditions, and has also been linked to alleviating neurodegenerative diseases. The focus of this review was to present the available evidence on the immunomodulatory effects of probiotics in the elderly population; aiming to gain a better understanding of their mechanism of action and to assess the progress made in utilizing probiotics as therapeutic interventions.
{"title":"A Revitalising Approach towards Aging: Unveiling the Potential Use of Probiotics for Wellness in Elderly Populations","authors":"Shanaya Phal Desai, Christine Kurian, Semanti Das, Stena Jesima Rebello, Sayanti Acharyya, K. Paari","doi":"10.31584/jhsmr.20231015","DOIUrl":"https://doi.org/10.31584/jhsmr.20231015","url":null,"abstract":"Probiotics have emerged as a potential alternative for treating various diseases affecting general population. Mounting data suggests that probiotics can be beneficial for older individuals, who often have weakened immune systems and are more susceptible to illnesses. Dysbiosis commonly occurs in elderly individuals, which is implicated as a major reason for various diseases. The effectiveness of probiotics is influenced by the specific strain and the dosage administered. Extensive studies have shown how probiotics affect prevalent issues, such as functional bowel diseases and other gastrointestinal disorders. Probiotics exert their effects by synthesizing different microbial peptides, such as bacteriocins, antibiotics, lipopolysaccharides, short-chain fatty acids, butyric acid, propionic acid and other specific secretory metabolites. The common probiotics that are found to benefit the health of elderly populations include Lactobacillus, Bifidobacterium lactis, Bacillus subtilis, Bifidobacterium longum and Bifidobacterium breve Further research is necessary to delve into the mechanism of action for both existing and novel probiotic strains for use in combating or aiding in diseases. Genetically, modified probiotics can be potentially used in the future to deliver immunity-restoring genes and as oral mode of vaccination in humans. Fecal microbiota transplantation has been gaining interest, used to restore gut conditions, and has also been linked to alleviating neurodegenerative diseases. The focus of this review was to present the available evidence on the immunomodulatory effects of probiotics in the elderly population; aiming to gain a better understanding of their mechanism of action and to assess the progress made in utilizing probiotics as therapeutic interventions.","PeriodicalId":36211,"journal":{"name":"Journal of Health Science and Medical Research","volume":"83 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139008066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Theresia CT Novy, Joudy Gessal, Andrew Suwadi, Ivan Christian Channel, Grace Fonda
Shoulder pain is a medical condition that may affect the well-being and compromise the quality of life of an individual, especially in the elderly. A supraspinatus tear is the most common cause of shoulder pain. Several treatments are available for this problem, such as surgical and conservative treatment. The surgical approach is found to be more efficacious but has a high rate of recurrence. Prolotherapy is one of the novel pain treatment modalities that could provide significant pain relief in musculoskeletal diseases. In this case report, we report a 53-year-old woman, who came to the outpatient clinic complaining of pain in her right shoulder for three months. The pain had been getting worse in the previous seven days, felt continuously throughout the day, and exacerbated when she raised her arm. The physical examination revealed a limited range of motion of active abduction and flexion with a positive drop arm test of the right shoulder. An ultrasound revealed a tear-drop appearance. The patient was treated with interventional pain management using dextrose prolotherapy. After undergoing prolotherapy treatment for three sessions over two months, the patient was declared completely healed from the supraspinatus tear. In conclusion, prolotherapy coupled with an ultrasound-guided procedure appears to be beneficial in alleviating pain and completely healing supraspinatus tears.
{"title":"Interventional Pain Management Using Dextrose Prolotherapy in Treating a Partial Supraspinatus Tear: A Case Report","authors":"Theresia CT Novy, Joudy Gessal, Andrew Suwadi, Ivan Christian Channel, Grace Fonda","doi":"10.31584/jhsmr.20231014","DOIUrl":"https://doi.org/10.31584/jhsmr.20231014","url":null,"abstract":"Shoulder pain is a medical condition that may affect the well-being and compromise the quality of life of an individual, especially in the elderly. A supraspinatus tear is the most common cause of shoulder pain. Several treatments are available for this problem, such as surgical and conservative treatment. The surgical approach is found to be more efficacious but has a high rate of recurrence. Prolotherapy is one of the novel pain treatment modalities that could provide significant pain relief in musculoskeletal diseases. In this case report, we report a 53-year-old woman, who came to the outpatient clinic complaining of pain in her right shoulder for three months. The pain had been getting worse in the previous seven days, felt continuously throughout the day, and exacerbated when she raised her arm. The physical examination revealed a limited range of motion of active abduction and flexion with a positive drop arm test of the right shoulder. An ultrasound revealed a tear-drop appearance. The patient was treated with interventional pain management using dextrose prolotherapy. After undergoing prolotherapy treatment for three sessions over two months, the patient was declared completely healed from the supraspinatus tear. In conclusion, prolotherapy coupled with an ultrasound-guided procedure appears to be beneficial in alleviating pain and completely healing supraspinatus tears.","PeriodicalId":36211,"journal":{"name":"Journal of Health Science and Medical Research","volume":"6 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139275065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rapphon Sawaddisan, R. Ransing, Chonnakarn Jatchavala
Objective: To compare the Thai versions of the Patient Health Questionnaire (PHQ-9) and the Edinburgh Postnatal Depression Scale (EPDS) and examine the associated factors with the degree of concordance for assessing depression in pregnant Thai women. Material and Methods: This was a cross-sectional study conducted in November-December 2022. The Thai versions of both the PHQ-9 and EPDS were completed by pregnant women at the Antenatal Care Clinic, Songklanagarind Hospital, Thailand. Descriptive data analysis and multivariate logistic regression were performed using The R Program to categorize “normal” and “increased risk of antenatal depression” and examine the statistical agreement, associated factors, and concordance between the two tools.Results: Of the 135 pregnant Thai women enrolled in the study, most lived in non-restive areas of southern Thailand (80.7%) with a mean age of 31.7 years. Most participants were found “normal” for antenatal depression screening by the Thai versions of both the PHQ-9 and the EPDS (89.6% and 88.9%, respectively). Complete concordance between the PHQ-9 and EPDS tests was found in 122 of the women, with 84.4% of all women found ‘normal’ and 5.9% found to have “increased risk of antenatal depression” with both questionnaires. The overall agreement between the 2 questionnaires was statistically significant (Kappa=0.4979, p-value<0.0001, Z=5.79). The statistical analysis identified no demographic factors associated with the concordance.Conclusion: The Thai versions of the PHQ-9 and the EPDS for antenatal depression screening had significantly moderate agreement. The statistical analysis found no factors associated with the concordance.
{"title":"Concordance of the Thai versions of the Patient Health Questionnaire and Edinburgh Post-natal Depression Scale for antenatal depression","authors":"Rapphon Sawaddisan, R. Ransing, Chonnakarn Jatchavala","doi":"10.31584/jhsmr.2023985","DOIUrl":"https://doi.org/10.31584/jhsmr.2023985","url":null,"abstract":"Objective: To compare the Thai versions of the Patient Health Questionnaire (PHQ-9) and the Edinburgh Postnatal Depression Scale (EPDS) and examine the associated factors with the degree of concordance for assessing depression in pregnant Thai women. Material and Methods: This was a cross-sectional study conducted in November-December 2022. The Thai versions of both the PHQ-9 and EPDS were completed by pregnant women at the Antenatal Care Clinic, Songklanagarind Hospital, Thailand. Descriptive data analysis and multivariate logistic regression were performed using The R Program to categorize “normal” and “increased risk of antenatal depression” and examine the statistical agreement, associated factors, and concordance between the two tools.Results: Of the 135 pregnant Thai women enrolled in the study, most lived in non-restive areas of southern Thailand (80.7%) with a mean age of 31.7 years. Most participants were found “normal” for antenatal depression screening by the Thai versions of both the PHQ-9 and the EPDS (89.6% and 88.9%, respectively). Complete concordance between the PHQ-9 and EPDS tests was found in 122 of the women, with 84.4% of all women found ‘normal’ and 5.9% found to have “increased risk of antenatal depression” with both questionnaires. The overall agreement between the 2 questionnaires was statistically significant (Kappa=0.4979, p-value<0.0001, Z=5.79). The statistical analysis identified no demographic factors associated with the concordance.Conclusion: The Thai versions of the PHQ-9 and the EPDS for antenatal depression screening had significantly moderate agreement. The statistical analysis found no factors associated with the concordance.","PeriodicalId":36211,"journal":{"name":"Journal of Health Science and Medical Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43062382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
W. Wichaidit, Rassamee Chotipanvithayakul, S. Assanangkornchai
Objective: to describe: 1) the prevalence of electronic cigarette use among Thai secondary school students, stratified by grade levels and sex; 2) the extent that depressive symptoms were associated with former and current use of electronic cigarette.Material and Methods: We conducted a cross-sectional study from secondary school students in Thailand in years 7, 9, and 11 of the 12-years educational system. We randomly sampled 113 schools in 21 provinces and Bangkok, randomly sampled classrooms in the school, and invited all students present in the sampled classrooms to participate in the study. All data were collected using self-administered questionnaires. We measured depressive symptoms using the Patient Health Questionnaire-2 (PHQ-2) instrument, and measured electronic cigarette use with adapted versions of existing instruments. Data analyses included descriptive statistics and logistic regression analyses with adjustment for sampling weights.Results: A total of 23,659 students responded and provided adequately completed questionnaires. Approximately 12.3% of the participants reported a lifetime history of using electronic cigarette. Electronic cigarette use was more common among males and older students. There seemed to be a threshold in the association between the level of depressive symptoms and ever vs. never use of electronic cigarette, and the association was strongest at a PHQ-2 score of 6 vs. 0 (adjusted odd ratio (OR)=1.72; 95% confidence interval (CI)=0.98, 3.03). A similar association was found between current vs. former or never use of electronic cigarette and having a PHQ-2 score of 6 vs. 0 (adjusted OR=1.84; 95% CI=0.96, 3.52).Conclusion: We found associations between depressive symptoms and electronic cigarette use. However, limitations with regard to the lack of temporality, measurement issues, and lack of generalizability should be considered as caveats in the interpretation of the study findings.
目的:描述:1)泰国中学生电子烟使用的流行程度，按年级和性别分层;2)抑郁症状与以前和现在使用电子烟的相关程度。材料和方法:我们对泰国12年教育体系中7年级、9年级和11年级的中学生进行了横断面研究。我们随机抽取21个省和曼谷的113所学校，随机抽取学校的教室，并邀请所有在抽样教室里的学生参与研究。所有数据均采用自填问卷收集。我们使用患者健康问卷-2 (PHQ-2)仪器测量抑郁症状，并使用现有仪器的改进版本测量电子烟的使用情况。数据分析包括描述性统计和逻辑回归分析，并对抽样权重进行调整。结果:共有23659名学生参与并提供了完整的问卷。大约12.3%的参与者报告了使用电子烟的终生史。电子烟的使用在男性和年龄较大的学生中更为常见。抑郁症状水平与曾经和从未使用电子烟之间似乎存在关联的阈值，并且在PHQ-2评分为6比0时相关性最强(调整奇比(OR)=1.72;95%置信区间(CI)=0.98, 3.03)。目前、以前或从未使用电子烟与PHQ-2评分6比0之间也存在类似的关联(调整后or =1.84;95% ci =0.96, 3.52)。结论:我们发现抑郁症状与电子烟使用之间存在关联。然而，缺乏时效性、测量问题和缺乏概括性方面的局限性应被视为解释研究结果的注意事项。
{"title":"Use of Electronic Cigarettes among Secondary School Students and their Association with Depressive Symptoms: Findings from a National Secondary School Survey in Thailand","authors":"W. Wichaidit, Rassamee Chotipanvithayakul, S. Assanangkornchai","doi":"10.31584/jhsmr.2023984","DOIUrl":"https://doi.org/10.31584/jhsmr.2023984","url":null,"abstract":"Objective: to describe: 1) the prevalence of electronic cigarette use among Thai secondary school students, stratified by grade levels and sex; 2) the extent that depressive symptoms were associated with former and current use of electronic cigarette.Material and Methods: We conducted a cross-sectional study from secondary school students in Thailand in years 7, 9, and 11 of the 12-years educational system. We randomly sampled 113 schools in 21 provinces and Bangkok, randomly sampled classrooms in the school, and invited all students present in the sampled classrooms to participate in the study. All data were collected using self-administered questionnaires. We measured depressive symptoms using the Patient Health Questionnaire-2 (PHQ-2) instrument, and measured electronic cigarette use with adapted versions of existing instruments. Data analyses included descriptive statistics and logistic regression analyses with adjustment for sampling weights.Results: A total of 23,659 students responded and provided adequately completed questionnaires. Approximately 12.3% of the participants reported a lifetime history of using electronic cigarette. Electronic cigarette use was more common among males and older students. There seemed to be a threshold in the association between the level of depressive symptoms and ever vs. never use of electronic cigarette, and the association was strongest at a PHQ-2 score of 6 vs. 0 (adjusted odd ratio (OR)=1.72; 95% confidence interval (CI)=0.98, 3.03). A similar association was found between current vs. former or never use of electronic cigarette and having a PHQ-2 score of 6 vs. 0 (adjusted OR=1.84; 95% CI=0.96, 3.52).Conclusion: We found associations between depressive symptoms and electronic cigarette use. However, limitations with regard to the lack of temporality, measurement issues, and lack of generalizability should be considered as caveats in the interpretation of the study findings.","PeriodicalId":36211,"journal":{"name":"Journal of Health Science and Medical Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44298894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shavya Aggarwal, Vinay Kumar Meena, S. Saluja, R. Nawal, A. Verma, Vasundhra Chhabra, Kritika Kaushik, Monika Garhwal
Objective: This study aimed to evaluate the role of immature platelet fractions (IPFs) and the degree of thrombocytopenia and their association with the severity of hypertensive disease of pregnancy.Material and Methods: One-hundred-and-ten primigravida females between 20-30 years of age, with a singleton live pregnancy, who attended the ANC clinic at Mahila Chikitsalaya, at over 20 weeks of gestation, with hypertensive disease of pregnancy, from November 2019 to August 2021, were enrolled in the study. Blood samples were obtained from all subjects at a regular ANC visits and at the time of admission in hypertensive disease of pregnancy and samples were analyzed within 4 hours of collection using an automated hematology system. IPFs were quantified using an optical fluorescence method. The levels of thrombocytopenia and immature platelet fractions were statistically analyzed against the severity of the disease.Results: The mean IPF was highest in females with eclampsia (18.12±3.59%), followed by severe preeclampsia (14.81±2.91%), mild preeclampsia (10.55±3.26%) and was smallest in females with gestational hypertension (10.08± 0.91%). This increase in IPF with increasing severity of hypertensive disorder of pregnancy was found to be statistically significant (p-value<0.001). The mean platelet count was lowest in females with eclampsia (1.60±0.41 lac/mm3, followed by severe pre-eclampsia (1.65±0.36 lac/mm3), mild pre-eclampsia (1.90±0.47 lac/mm3) and highest in females with gestational hypertension (2.57±0.25 lac/mm3) (p-value<0.001)Conclusion: Higher IPFs had a negative correlation with lower platelet counts and was significantly correlated s with disease severity. Changes in IPF in HDP may occur before development of thrombocytopenia, thus providing an opportunity to plan preemptive management strategies to reduce fetomaternal morbidity and mortality.
{"title":"Immature Platelet Fraction as a Predictive Marker of Severity in Hypertensive Disease of Pregnancy: a Prospective Cross-Sectional Study","authors":"Shavya Aggarwal, Vinay Kumar Meena, S. Saluja, R. Nawal, A. Verma, Vasundhra Chhabra, Kritika Kaushik, Monika Garhwal","doi":"10.31584/jhsmr.2023983","DOIUrl":"https://doi.org/10.31584/jhsmr.2023983","url":null,"abstract":"Objective: This study aimed to evaluate the role of immature platelet fractions (IPFs) and the degree of thrombocytopenia and their association with the severity of hypertensive disease of pregnancy.Material and Methods: One-hundred-and-ten primigravida females between 20-30 years of age, with a singleton live pregnancy, who attended the ANC clinic at Mahila Chikitsalaya, at over 20 weeks of gestation, with hypertensive disease of pregnancy, from November 2019 to August 2021, were enrolled in the study. Blood samples were obtained from all subjects at a regular ANC visits and at the time of admission in hypertensive disease of pregnancy and samples were analyzed within 4 hours of collection using an automated hematology system. IPFs were quantified using an optical fluorescence method. The levels of thrombocytopenia and immature platelet fractions were statistically analyzed against the severity of the disease.Results: The mean IPF was highest in females with eclampsia (18.12±3.59%), followed by severe preeclampsia (14.81±2.91%), mild preeclampsia (10.55±3.26%) and was smallest in females with gestational hypertension (10.08± 0.91%). This increase in IPF with increasing severity of hypertensive disorder of pregnancy was found to be statistically significant (p-value<0.001). The mean platelet count was lowest in females with eclampsia (1.60±0.41 lac/mm3, followed by severe pre-eclampsia (1.65±0.36 lac/mm3), mild pre-eclampsia (1.90±0.47 lac/mm3) and highest in females with gestational hypertension (2.57±0.25 lac/mm3) (p-value<0.001)Conclusion: Higher IPFs had a negative correlation with lower platelet counts and was significantly correlated s with disease severity. Changes in IPF in HDP may occur before development of thrombocytopenia, thus providing an opportunity to plan preemptive management strategies to reduce fetomaternal morbidity and mortality. ","PeriodicalId":36211,"journal":{"name":"Journal of Health Science and Medical Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49562762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dessy Triana, M. Martini, A. Suwondo, Muchlis Achsan Udji Sofro Achsan Udji Sofro, S. Hadisaputro, S. Suhartono
Objective: The causes for the increasing number of dengue cases are complex and multifactorial. The approach taken must combine influencing factors, and comprehensive prevention strategy is needed that includes all the components of factors that influence dengue disease to predict the incidence of the disease. This research aimed to analyze the relationship between population and climate components including population density, population density <15 years old, sanitation, temperature, humidity and rainfall, on the incidence rate of Dengue Hemorrhagic Fever (DHF).Material and Methods: This study used a cross-sectional design, with the research sample being all sub-districts in Bengkulu City, Indonesia (67 sub-districts). Data analysis was conducted using structural equation modeling to create a dengue modeling based on population and climate factors, through the SmartPLS application.Results: Population and climate factors had a significant relationship with the incidence rate of dengue, with p-values of 0.018 and 0.000, respectively. Population and climate factors had a percentage effect on the incidence rate of dengue (36.9%).Conclusion: Population and climate factors had an influence of 36.9% on the incidence of dengue. There were many factors affecting the incidence of dengue, so a more comprehensive modeling of the various influencing factors is needed. Dengue modeling is crucial as an early warning system for the early prevention of dengue outbreaks, so that the control strategies implemented can be more effective.
{"title":"Dengue Hemorrhagic Fever (DHF): Vulnerability Model Based on Population and Climate Factors in Bengkulu City","authors":"Dessy Triana, M. Martini, A. Suwondo, Muchlis Achsan Udji Sofro Achsan Udji Sofro, S. Hadisaputro, S. Suhartono","doi":"10.31584/jhsmr.2023982","DOIUrl":"https://doi.org/10.31584/jhsmr.2023982","url":null,"abstract":"Objective: The causes for the increasing number of dengue cases are complex and multifactorial. The approach taken must combine influencing factors, and comprehensive prevention strategy is needed that includes all the components of factors that influence dengue disease to predict the incidence of the disease. This research aimed to analyze the relationship between population and climate components including population density, population density <15 years old, sanitation, temperature, humidity and rainfall, on the incidence rate of Dengue Hemorrhagic Fever (DHF).Material and Methods: This study used a cross-sectional design, with the research sample being all sub-districts in Bengkulu City, Indonesia (67 sub-districts). Data analysis was conducted using structural equation modeling to create a dengue modeling based on population and climate factors, through the SmartPLS application.Results: Population and climate factors had a significant relationship with the incidence rate of dengue, with p-values of 0.018 and 0.000, respectively. Population and climate factors had a percentage effect on the incidence rate of dengue (36.9%).Conclusion: Population and climate factors had an influence of 36.9% on the incidence of dengue. There were many factors affecting the incidence of dengue, so a more comprehensive modeling of the various influencing factors is needed. Dengue modeling is crucial as an early warning system for the early prevention of dengue outbreaks, so that the control strategies implemented can be more effective.","PeriodicalId":36211,"journal":{"name":"Journal of Health Science and Medical Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49409987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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