Pub Date : 2024-10-11DOI: 10.1016/j.patter.2024.101058
J Scott Christianson
The advent of easy-to-use large language models (LLMs) such as ChatGPT has started an arms race in academia between students who use AI and faculty trying to detect that use. This unproductive battle must end, and faculty can help broker peace by rethinking assignments and using LLMs where appropriate.
{"title":"End the AI detection arms race.","authors":"J Scott Christianson","doi":"10.1016/j.patter.2024.101058","DOIUrl":"10.1016/j.patter.2024.101058","url":null,"abstract":"<p><p>The advent of easy-to-use large language models (LLMs) such as ChatGPT has started an arms race in academia between students who use AI and faculty trying to detect that use. This unproductive battle must end, and faculty can help broker peace by rethinking assignments and using LLMs where appropriate.</p>","PeriodicalId":36242,"journal":{"name":"Patterns","volume":"5 10","pages":"101058"},"PeriodicalIF":6.7,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11573885/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142682915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-10eCollection Date: 2024-11-08DOI: 10.1016/j.patter.2024.101074
Hao Cui, Taha Yasseri
Current societal challenges exceed the capacity of humans operating either alone or collectively. As AI evolves, its role within human collectives will vary from an assistive tool to a participatory member. Humans and AI possess complementary capabilities that, together, can surpass the collective intelligence of either humans or AI in isolation. However, the interactions in human-AI systems are inherently complex, involving intricate processes and interdependencies. This review incorporates perspectives from complex network science to conceptualize a multilayer representation of human-AI collective intelligence, comprising cognition, physical, and information layers. Within this multilayer network, humans and AI agents exhibit varying characteristics; humans differ in diversity from surface-level to deep-level attributes, while AI agents range in degrees of functionality and anthropomorphism. We explore how agents' diversity and interactions influence the system's collective intelligence and analyze real-world instances of AI-enhanced collective intelligence. We conclude by considering potential challenges and future developments in this field.
{"title":"AI-enhanced collective intelligence.","authors":"Hao Cui, Taha Yasseri","doi":"10.1016/j.patter.2024.101074","DOIUrl":"10.1016/j.patter.2024.101074","url":null,"abstract":"<p><p>Current societal challenges exceed the capacity of humans operating either alone or collectively. As AI evolves, its role within human collectives will vary from an assistive tool to a participatory member. Humans and AI possess complementary capabilities that, together, can surpass the collective intelligence of either humans or AI in isolation. However, the interactions in human-AI systems are inherently complex, involving intricate processes and interdependencies. This review incorporates perspectives from complex network science to conceptualize a multilayer representation of human-AI collective intelligence, comprising cognition, physical, and information layers. Within this multilayer network, humans and AI agents exhibit varying characteristics; humans differ in diversity from surface-level to deep-level attributes, while AI agents range in degrees of functionality and anthropomorphism. We explore how agents' diversity and interactions influence the system's collective intelligence and analyze real-world instances of AI-enhanced collective intelligence. We conclude by considering potential challenges and future developments in this field.</p>","PeriodicalId":36242,"journal":{"name":"Patterns","volume":"5 11","pages":"101074"},"PeriodicalIF":6.7,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11573907/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142682992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-09eCollection Date: 2024-11-08DOI: 10.1016/j.patter.2024.101073
Chumphol Bunkhumpornpat, Ekkarat Boonchieng, Varin Chouvatut, David Lipsky
Class imbalance is a challenge that affects the prediction rate on a minority class. To remedy this problem, various SMOTEs (synthetic minority over-sampling techniques) have been designed to populate synthetic minority instances. Some SMOTEs operate on the border of a minority class, while others concentrate on the class core. Unfortunately, it is difficult to put the right SMOTE to the right dataset because distributions of classes are varied and might not be obvious. This paper proposes a new technique, called FLEX-SMOTE, that is flexible enough to be used with all sorts of datasets. The key idea is that an over-sampled region is selected based on the characteristics of minority classes. This approach is based on a density function that is used to describe the distributions of minority classes. Herein, we have included experimental results showing that FLEX-SMOTE can significantly improve the predictive performance of a minority class.
{"title":"FLEX-SMOTE: Synthetic over-sampling technique that flexibly adjusts to different minority class distributions.","authors":"Chumphol Bunkhumpornpat, Ekkarat Boonchieng, Varin Chouvatut, David Lipsky","doi":"10.1016/j.patter.2024.101073","DOIUrl":"10.1016/j.patter.2024.101073","url":null,"abstract":"<p><p>Class imbalance is a challenge that affects the prediction rate on a minority class. To remedy this problem, various SMOTEs (synthetic minority over-sampling techniques) have been designed to populate synthetic minority instances. Some SMOTEs operate on the border of a minority class, while others concentrate on the class core. Unfortunately, it is difficult to put the right SMOTE to the right dataset because distributions of classes are varied and might not be obvious. This paper proposes a new technique, called FLEX-SMOTE, that is flexible enough to be used with all sorts of datasets. The key idea is that an over-sampled region is selected based on the characteristics of minority classes. This approach is based on a density function that is used to describe the distributions of minority classes. Herein, we have included experimental results showing that FLEX-SMOTE can significantly improve the predictive performance of a minority class.</p>","PeriodicalId":36242,"journal":{"name":"Patterns","volume":"5 11","pages":"101073"},"PeriodicalIF":6.7,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11573909/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142682996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01eCollection Date: 2024-11-08DOI: 10.1016/j.patter.2024.101064
Patrick Kuckertz, Jan Göpfert, Oliver Karras, David Neuroth, Julian Schönau, Rodrigo Pueblas, Stephan Ferenz, Felix Engel, Noah Pflugradt, Jann M Weinand, Astrid Nieße, Sören Auer, Detlef Stolten
The reuse of research software is central to research efficiency and academic exchange. The application of software enables researchers to reproduce, validate, and expand upon study findings. The analysis of open-source code aids in the comprehension, comparison, and integration of approaches. Often, however, no further use occurs because relevant software cannot be found or is incompatible with existing research processes. This results in repetitive software development, which impedes the advancement of individual researchers and entire research communities. In this article, the DataDesc (Data Description) framework is presented-an approach to describing data models of software interfaces with machine-actionable metadata. In addition to a specialized metadata schema, an exchange format and support tools for easy collection and the automated publishing of software documentation are introduced. This approach practically increases the FAIRness, i.e., findability, accessibility, interoperability, and reusability, of research software as well as effectively promotes its impact on research.
{"title":"DataDesc: A framework for creating and sharing technical metadata for research software interfaces.","authors":"Patrick Kuckertz, Jan Göpfert, Oliver Karras, David Neuroth, Julian Schönau, Rodrigo Pueblas, Stephan Ferenz, Felix Engel, Noah Pflugradt, Jann M Weinand, Astrid Nieße, Sören Auer, Detlef Stolten","doi":"10.1016/j.patter.2024.101064","DOIUrl":"10.1016/j.patter.2024.101064","url":null,"abstract":"<p><p>The reuse of research software is central to research efficiency and academic exchange. The application of software enables researchers to reproduce, validate, and expand upon study findings. The analysis of open-source code aids in the comprehension, comparison, and integration of approaches. Often, however, no further use occurs because relevant software cannot be found or is incompatible with existing research processes. This results in repetitive software development, which impedes the advancement of individual researchers and entire research communities. In this article, the DataDesc (Data Description) framework is presented-an approach to describing data models of software interfaces with machine-actionable metadata. In addition to a specialized metadata schema, an exchange format and support tools for easy collection and the automated publishing of software documentation are introduced. This approach practically increases the FAIRness, i.e., findability, accessibility, interoperability, and reusability, of research software as well as effectively promotes its impact on research.</p>","PeriodicalId":36242,"journal":{"name":"Patterns","volume":"5 11","pages":"101064"},"PeriodicalIF":6.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11573911/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142682994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-30eCollection Date: 2024-10-11DOI: 10.1016/j.patter.2024.101063
Euijeong Song, Minsuh Kim, Siyoung Lee, Hui-Wen Liu, Jihyun Kim, Dong-Hee Choi, Roger Kamm, Seok Chung, Ji Hun Yang, Tae Hwan Kwak
Organoids and 3D imaging techniques are crucial for studying human tissue structure and function, but traditional 3D reconstruction methods are expensive and time consuming, relying on complete z stack confocal microscopy data. This paper introduces VONet, a deep learning-based system for 3D organoid rendering that uses a fully convolutional neural network to reconstruct entire 3D structures from a minimal number of z stack images. VONet was trained on a library of over 39,000 virtual organoids (VOs) with diverse structural features and achieved an average intersection over union of 0.82 in performance validation. Remarkably, VONet can predict the structure of deeper focal plane regions, unseen by conventional confocal microscopy. This innovative approach and VO dataset offer significant advancements in 3D bioimaging technologies.
类器官和三维成像技术对研究人体组织结构和功能至关重要,但传统的三维重建方法依赖于完整的z堆栈共聚焦显微镜数据,既昂贵又耗时。本文介绍的 VONet 是一种基于深度学习的三维类器官渲染系统,它使用完全卷积神经网络从最少的 z 叠加图像重建整个三维结构。VONet 在一个包含 39,000 多个具有不同结构特征的虚拟类器官(VO)的库中进行了训练,并在性能验证中取得了 0.82 的平均交集比结合率。值得注意的是,VONet 可以预测传统共聚焦显微镜无法看到的更深焦平面区域的结构。这种创新方法和 VO 数据集为三维生物成像技术带来了重大进步。
{"title":"VONet: A deep learning network for 3D reconstruction of organoid structures with a minimal number of confocal images.","authors":"Euijeong Song, Minsuh Kim, Siyoung Lee, Hui-Wen Liu, Jihyun Kim, Dong-Hee Choi, Roger Kamm, Seok Chung, Ji Hun Yang, Tae Hwan Kwak","doi":"10.1016/j.patter.2024.101063","DOIUrl":"10.1016/j.patter.2024.101063","url":null,"abstract":"<p><p>Organoids and 3D imaging techniques are crucial for studying human tissue structure and function, but traditional 3D reconstruction methods are expensive and time consuming, relying on complete z stack confocal microscopy data. This paper introduces VONet, a deep learning-based system for 3D organoid rendering that uses a fully convolutional neural network to reconstruct entire 3D structures from a minimal number of z stack images. VONet was trained on a library of over 39,000 virtual organoids (VOs) with diverse structural features and achieved an average intersection over union of 0.82 in performance validation. Remarkably, VONet can predict the structure of deeper focal plane regions, unseen by conventional confocal microscopy. This innovative approach and VO dataset offer significant advancements in 3D bioimaging technologies.</p>","PeriodicalId":36242,"journal":{"name":"Patterns","volume":"5 10","pages":"101063"},"PeriodicalIF":6.7,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11573902/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142682989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Manual review is an integral part of any study. As the cost of data generation continues to decrease, the rapid rise in large-scale multi-omic studies calls for a modular, flexible framework to perform what is currently a tedious, error-prone process. We developed AnnoMate, a Python-based package built with Plotly Dash that creates interactive, highly customizable dashboards for reviewing and annotating data. Its object-oriented framework enables easy development and modification of custom dashboards for specific manual review tasks. We utilized this framework to implement “reviewer” dashboards for various tasks often performed in cancer genome sequencing studies.
{"title":"AnnoMate: Exploring and annotating integrated molecular data through custom interactive visualizations","authors":"Claudia Chu, Conor Messer, Samantha Van Seters, Mendy Miller, Kristy Schlueter-Kuck, Gad Getz","doi":"10.1016/j.patter.2024.101060","DOIUrl":"https://doi.org/10.1016/j.patter.2024.101060","url":null,"abstract":"<p>Manual review is an integral part of any study. As the cost of data generation continues to decrease, the rapid rise in large-scale multi-omic studies calls for a modular, flexible framework to perform what is currently a tedious, error-prone process. We developed <em>AnnoMate</em>, a Python-based package built with Plotly Dash that creates interactive, highly customizable dashboards for reviewing and annotating data. Its object-oriented framework enables easy development and modification of custom dashboards for specific manual review tasks. We utilized this framework to implement “reviewer” dashboards for various tasks often performed in cancer genome sequencing studies.</p>","PeriodicalId":36242,"journal":{"name":"Patterns","volume":"19 1","pages":""},"PeriodicalIF":6.5,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142250275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-13DOI: 10.1016/j.patter.2024.101049
Erik-Jan van Kesteren
For over 30 years, synthetic data have been heralded as a solution to make sensitive datasets accessible. However, despite much research effort, its adoption as a tool for research with sensitive data is lacking. This article argues that to make progress in this regard, the data science community should focus on improving the accessibility of existing privacy-friendly synthesis techniques.
{"title":"To democratize research with sensitive data, we should make synthetic data more accessible","authors":"Erik-Jan van Kesteren","doi":"10.1016/j.patter.2024.101049","DOIUrl":"https://doi.org/10.1016/j.patter.2024.101049","url":null,"abstract":"<p>For over 30 years, synthetic data have been heralded as a solution to make sensitive datasets accessible. However, despite much research effort, its adoption as a tool for research with sensitive data is lacking. This article argues that to make progress in this regard, the data science community should focus on improving the accessibility of existing privacy-friendly synthesis techniques.</p>","PeriodicalId":36242,"journal":{"name":"Patterns","volume":"8 1","pages":""},"PeriodicalIF":6.5,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142196804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-13DOI: 10.1016/j.patter.2024.101061
Andrew L. Hufton
No Abstract
无摘要
{"title":"Balancing innovation and integrity in peer review","authors":"Andrew L. Hufton","doi":"10.1016/j.patter.2024.101061","DOIUrl":"https://doi.org/10.1016/j.patter.2024.101061","url":null,"abstract":"No Abstract","PeriodicalId":36242,"journal":{"name":"Patterns","volume":"85 1","pages":""},"PeriodicalIF":6.5,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142196802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-13DOI: 10.1016/j.patter.2024.101040
Mol Mir, Stephanie H. Nowotarski
The “stacking cell puzzle” is a data visualization project consisting of a three-dimensional puzzle made with electron microscopy data of planarian cells.
堆叠细胞拼图 "是一个数据可视化项目,包括一个利用扁平动物细胞电子显微镜数据制作的三维拼图。
{"title":"The stacking cell puzzle","authors":"Mol Mir, Stephanie H. Nowotarski","doi":"10.1016/j.patter.2024.101040","DOIUrl":"https://doi.org/10.1016/j.patter.2024.101040","url":null,"abstract":"<p>The “stacking cell puzzle” is a data visualization project consisting of a three-dimensional puzzle made with electron microscopy data of planarian cells.</p>","PeriodicalId":36242,"journal":{"name":"Patterns","volume":"453 1","pages":""},"PeriodicalIF":6.5,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142196803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-12DOI: 10.1016/j.patter.2024.101059
Mingxuan Liu, Yilin Ning, Yuhe Ke, Yuqing Shang, Bibhas Chakraborty, Marcus Eng Hock Ong, Roger Vaughan, Nan Liu
The escalating integration of machine learning in high-stakes fields such as healthcare raises substantial concerns about model fairness. We propose an interpretable framework, fairness-aware interpretable modeling (FAIM), to improve model fairness without compromising performance, featuring an interactive interface to identify a “fairer” model from a set of high-performing models and promoting the integration of data-driven evidence and clinical expertise to enhance contextualized fairness. We demonstrate FAIM’s value in reducing intersectional biases arising from race and sex by predicting hospital admission with two real-world databases, the Medical Information Mart for Intensive Care IV Emergency Department (MIMIC-IV-ED) and the database collected from Singapore General Hospital Emergency Department (SGH-ED). For both datasets, FAIM models not only exhibit satisfactory discriminatory performance but also significantly mitigate biases as measured by well-established fairness metrics, outperforming commonly used bias mitigation methods. Our approach demonstrates the feasibility of improving fairness without sacrificing performance and provides a modeling mode that invites domain experts to engage, fostering a multidisciplinary effort toward tailored AI fairness.
机器学习与医疗保健等高风险领域的整合不断升级,引起了人们对模型公平性的极大关注。我们提出了一个可解释的框架--公平感知可解释建模(FAIM),以在不影响性能的情况下提高模型的公平性,其特点是从一组高性能模型中识别出 "更公平 "模型的交互式界面,并促进数据驱动的证据和临床专业知识的整合,以提高情境公平性。我们利用两个真实世界的数据库--重症监护医学信息市场 IV 急诊部(MIMIC-IV-ED)和新加坡中央医院急诊部(SGH-ED)收集的数据库--预测入院情况,证明了 FAIM 在减少种族和性别交叉偏见方面的价值。对于这两个数据集,FAIM 模型不仅表现出令人满意的判别性能,而且还能显著减轻偏差,这是用公认的公平性指标来衡量的,优于常用的减轻偏差方法。我们的方法证明了在不牺牲性能的情况下提高公平性的可行性,并提供了一种可邀请领域专家参与的建模模式,促进了多学科合作,以实现量身定制的人工智能公平性。
{"title":"FAIM: Fairness-aware interpretable modeling for trustworthy machine learning in healthcare","authors":"Mingxuan Liu, Yilin Ning, Yuhe Ke, Yuqing Shang, Bibhas Chakraborty, Marcus Eng Hock Ong, Roger Vaughan, Nan Liu","doi":"10.1016/j.patter.2024.101059","DOIUrl":"https://doi.org/10.1016/j.patter.2024.101059","url":null,"abstract":"<p>The escalating integration of machine learning in high-stakes fields such as healthcare raises substantial concerns about model fairness. We propose an interpretable framework, fairness-aware interpretable modeling (FAIM), to improve model fairness without compromising performance, featuring an interactive interface to identify a “fairer” model from a set of high-performing models and promoting the integration of data-driven evidence and clinical expertise to enhance contextualized fairness. We demonstrate FAIM’s value in reducing intersectional biases arising from race and sex by predicting hospital admission with two real-world databases, the Medical Information Mart for Intensive Care IV Emergency Department (MIMIC-IV-ED) and the database collected from Singapore General Hospital Emergency Department (SGH-ED). For both datasets, FAIM models not only exhibit satisfactory discriminatory performance but also significantly mitigate biases as measured by well-established fairness metrics, outperforming commonly used bias mitigation methods. Our approach demonstrates the feasibility of improving fairness without sacrificing performance and provides a modeling mode that invites domain experts to engage, fostering a multidisciplinary effort toward tailored AI fairness.</p>","PeriodicalId":36242,"journal":{"name":"Patterns","volume":"195 1","pages":""},"PeriodicalIF":6.5,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142196805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}