Artificial intelligence (AI) is considered one of the most revolutionary technological developments today. But can it replace teachers in education? A new proposal in São Paulo, Brazil, suggests this might be possible, but it raises significant concerns about educational quality and equity.
Rapid advances in human brain organoid technologies have prompted the question of their consciousness. Although brain organoids resemble many facets of the brain, their shortcomings strongly suggest that they do not fit any of the operational definitions of consciousness. As organoids gain internal processing systems through statistical learning and closed loop algorithms, interact with the external world, and become embodied through fusion with other organ systems, questions of biosynthetic consciousness will arise.
Reconstructing neuronal morphology is vital for classifying neurons and mapping brain connectivity. However, it remains a significant challenge due to its complex structure, dense distribution, and low image contrast. In particular, AI-assisted methods often yield numerous errors that require extensive manual intervention. Therefore, reconstructing hundreds of neurons is already a daunting task for general research projects. A key issue is the lack of specialized training for challenging regions due to inadequate data and training methods. This study extracted 2,800 challenging neuronal blocks and categorized them into multiple density levels. Furthermore, we enhanced images using an axial continuity-based network that improved three-dimensional voxel resolution while reducing the difficulty of neuron recognition. Comparing the pre- and post-enhancement results in automatic algorithms using fluorescence micro-optical sectioning tomography (fMOST) data, we observed a significant increase in the recall rate. Our study not only enhances the throughput of reconstruction but also provides a fundamental dataset for tangled neuron reconstruction.
To make explainable artificial intelligence (XAI) systems trustworthy, understanding harmful effects is important. In this paper, we address an important yet unarticulated type of negative effect in XAI. We introduce explainability pitfalls (EPs), unanticipated negative downstream effects from AI explanations manifesting even when there is no intention to manipulate users. EPs are different from dark patterns, which are intentionally deceptive practices. We articulate the concept of EPs by demarcating it from dark patterns and highlighting the challenges arising from uncertainties around pitfalls. We situate and operationalize the concept using a case study that showcases how, despite best intentions, unsuspecting negative effects, such as unwarranted trust in numerical explanations, can emerge. We propose proactive and preventative strategies to address EPs at three interconnected levels: research, design, and organizational. We discuss design and societal implications around reframing AI adoption, recalibrating stakeholder empowerment, and resisting the “move fast and break things” mindset.
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