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Optimum standardization of cause-of-death certification procedures in healthcare facilities: A medicolegal initiative 医疗机构死因证明程序的最佳标准化:一项医学法律倡议
Q3 Medicine Pub Date : 2023-01-01 DOI: 10.1016/j.fsir.2023.100329
Mamdouh Kamal Zaki , Zahraa Khalifa Sobh
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引用次数: 0
Analysis of prescription eyewear for personal identification in forensic optometry 法医验光中个人鉴定处方眼镜的分析
Q3 Medicine Pub Date : 2023-01-01 DOI: 10.1016/j.fsir.2023.100326
R. Aparna , R. Shanti Iyer , Mebin Wilson Thomas
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引用次数: 0
Autopsy, histological and toxicological findings in deaths associated with new psychoactive substances (NPS): a study with 12 autopsies 与新型精神活性物质(NPS)有关的死亡的尸检、组织学和毒理学发现:一项对12例尸检的研究
Q3 Medicine Pub Date : 2023-01-01 DOI: 10.1016/j.fsir.2023.100322
A. Levasseur , A. Knapp-Gisclon , C. Mayer-Duverneuil , I. Etting , G. Lorin de la Grandmaison , J.-C. Alvarez
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引用次数: 1
Health and Justice: Experiences of the forensic medical examination after sexual assault 卫生和司法:性侵犯后法医检查的经验
Q3 Medicine Pub Date : 2022-12-01 DOI: 10.1016/j.fsir.2022.100297
Suzanne Manning, Helena Rattray-Te Mana

Sexual assault is a chronic problem around the globe, and those who choose to report a sexual assault are faced with further traumatic experiences within the justice system. There are many points at which these experiences could be improved, to support the complainant through the process. This qualitative evidence synthesis focused on the forensic medical examination (FME) as a point for potential improvement. Literature that focused on patient and medical practitioner experiences of the FME were reviewed and analyzed for themes that might suggest ways in which the FME process could be made better from the patient’s perspective. Three themes were identified. One related to the tension between the dual aims of the FME, of providing therapeutic healthcare and evidence for police investigation and prosecution. For the patients, these dual aims needed to be seen as healthcare first and forensic evidence as a secondary decision. The second theme was around the experience of the FME as traumatic, and the need for specialist training for practitioners was affirmed. Although women practitioners were preferred, the behavior and skills of the practitioner was more important. Their practice needed to be trauma-informed and patient-centered. The third theme was around optimizing the FME in terms of collecting the evidence that would have the most impact on the subsequent police and judicial processes, depending on the situation. For this optimization, further research is needed to trace the linkages between evidence and justice outcomes.

性侵犯在全球都是一个长期存在的问题,那些选择报告性侵犯的人在司法系统中面临着进一步的创伤经历。在许多方面,这些经历可以得到改善,以支持投诉人完成整个过程。这种定性证据综合侧重于法医检查,作为可能改进的一个方面。我们回顾和分析了关于病人和医生对FME体验的文献,以寻找从病人的角度改进FME过程的方法。确定了三个主题。其中一个与FME的双重目标之间的紧张关系有关,即提供治疗性保健和为警方调查和起诉提供证据。对于患者来说,这些双重目标需要被视为医疗保健第一和法医证据作为次要的决定。第二个主题是关于FME的创伤性经历,并肯定了对从业者进行专业培训的必要性。虽然女性从业者优先,但从业者的行为和技能更重要。他们的实践需要了解创伤并以病人为中心。第三个主题是围绕根据情况,在收集对随后的警察和司法程序产生最大影响的证据方面优化FME。为了实现这一优化,需要进一步研究证据与司法结果之间的联系。
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引用次数: 1
A new implementation of a semi-continuous method for DNA mixture interpretation 一种半连续DNA混合解释方法的新实现
Q3 Medicine Pub Date : 2022-12-01 DOI: 10.1016/j.fsir.2022.100281
Jacob Alfieri , Michael D. Coble , Carole Conroy , Angela Dahl , Douglas R. Hares , Bruce S. Weir , Charles Wolock , Edward Zhao , Hanley Kingston , Timothy W. Zolandz

A new calculation module within the PopStats module of the CODIS software package, based on the underlying mathematics presented in the MixKin software package, has been developed for assigning the Likelihood Ratio (LR) of DNA mixture profiles. This module uses a semi-continuous model that allows for population structure and allelic drop-out and drop-in but does not require allelic peak heights or other laboratory-specific parameters. This new implementation (named SC Mixture), like MixKin, does not specify or estimate a probability of drop-out. Instead, each contributor to a mixture has an independent drop-out rate, and the probability of the mixture profile for a specified proposition concerning the contributors is integrated over the range of possible drop-out rates. The allelic drop-in rate and the population structure parameter, theta, used by the software are specified by the user. The user can examine up to five contributors to a mixture, however, conditioning on assumed contributors and limiting the number of unknowns in both numerator and denominator hypotheses greatly improves performance. We report results from an extensive validation study performed for ten mixtures with each of one (single source), two, three, four, or five contributors, with four combinations of drop-in rate and a population structure parameter. Each mixture was run as a complete profile or with the random removal of alleles to simulate drop-out. All 1620 combinations were evaluated with PopStats, MixKin, and LRmix and considerable consistency was found among the results with all three packages.

基于MixKin软件包提供的基础数学,在CODIS软件包的PopStats模块中开发了一个新的计算模块,用于分配DNA混合谱的似然比(LR)。该模块使用半连续模型,允许种群结构和等位基因的缺失和缺失,但不需要等位基因峰值高度或其他实验室特定参数。这个新的实现(名为SC混合物),像MixKin一样,不指定或估计退出的概率。相反,混合物的每个贡献者都有一个独立的退出率,并且关于贡献者的特定命题的混合物轮廓的概率在可能的退出率范围内进行集成。该软件使用的等位基因滴入率和种群结构参数theta由用户指定。用户最多可以检查混合物的五个贡献者,然而,根据假设的贡献者进行调节并限制分子和分母假设中的未知数数量大大提高了性能。我们报告了一项广泛的验证研究的结果,该研究对10种混合物进行了验证,每种混合物有一个(单一来源)、两个、三个、四个或五个贡献者,有四种跌落率和种群结构参数的组合。每个混合物作为一个完整的档案运行或随机去除等位基因来模拟辍学。使用PopStats、MixKin和LRmix对所有1620种组合进行了评估,并且在所有三种包装的结果中发现了相当大的一致性。
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引用次数: 0
An assessment of dental age in a select South African sample using the Willems scoring systems 使用Willems评分系统对选定南非样本的牙齿年龄进行评估
Q3 Medicine Pub Date : 2022-12-01 DOI: 10.1016/j.fsir.2022.100296
S. Ishwarkumar , P. Pillay , M. Chetty , KS Satyapal

Purpose

Age estimation plays a pivotal role in the forensics sciences, medico-legal and clinical dentistry fields. The Willems method has gained significant recognition over the past two decades; however, the accuracy of it varies between population groups and across different regions within a country. Consequently, the present study aimed to investigate the reliability of the Willems scoring systems to a select South African population.

Methods

A cross-sectional assessment of 600 digital panoramic radiographs of patients (n = 600: 300 South African Black and 300 South African Indian) between 5.00 and 19.99 years old were employed retrospectively. The dental age was calculated utilizing the Willems et al. (2001) and Willems et al. (2018) scoring systems. Discrepancies between the chronological and dental ages were statistically analyzed.

Results

An over-estimation of dental age utilizing the Willems et al. (2001) and Willems et al. (2018) scoring systems was recorded in the selected sample of KwaZulu-Natal. A significant statistical difference between the chronological age and estimated dental age was recorded for both methodologies. Therefore, this study attempted to increase the accuracy of the Willems scoring system in a selected sample of South Africa by generating the following two novel population-specific age predictive models (excluding and including third molars).

Conclusion

The population-specific model performed better than the Willems scoring systems for the select sample, with the lowest mean errors and an insignificant statistical discrepancy noted between the chronological and dental ages (p-value >0.05). Therefore, these population-specific models may be used for forensic and medico-legal cases within this region.

目的估计在法医学、医学法律和临床牙科领域起着举足轻重的作用。在过去的二十年里,Willems方法获得了极大的认可;然而,它的准确性在不同的人口群体和一个国家的不同地区有所不同。因此,本研究旨在调查威廉姆斯评分系统的可靠性,以选择南非人口。方法回顾性分析600例年龄在5.00 ~ 19.99岁的患者(n = 600: 300名南非黑人和300名南非印第安人)的数字全景x线片的横截面评估。使用Willems et al.(2001)和Willems et al.(2018)评分系统计算牙龄。统计分析实足年龄与牙龄之间的差异。结果利用Willems et al.(2001)和Willems et al.(2018)评分系统在夸祖鲁-纳塔尔省的选定样本中记录了对牙齿年龄的高估。两种方法记录了实足年龄和估计牙龄之间的显著统计差异。因此,本研究试图通过生成以下两种新型人群特定年龄预测模型(不包括和包括第三磨牙)来提高Willems评分系统在南非选定样本中的准确性。结论针对特定人群的模型在选择样本时优于Willems评分系统,平均误差最小,实足年龄与牙龄之间的统计学差异不显著(p值>0.05)。因此,这些针对特定人群的模型可用于该区域的法医和医学法律案件。
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引用次数: 0
Commentary on “Mantrailing as evidence in court?” Forensic Science International: Reports, 3 (2021), 100204 《国际法医学:报告》,3(2021),100204
Q3 Medicine Pub Date : 2022-12-01 DOI: 10.1016/j.fsir.2022.100305
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引用次数: 1
A morphometric assessment of developing permanent dentition for age and sex estimation in a select South African sample 发展恒牙的年龄和性别估计的形态计量学评估在一个选择的南非样本
Q3 Medicine Pub Date : 2022-12-01 DOI: 10.1016/j.fsir.2022.100294
S. Ishwarkumar , P. Pillay , M. Chetty , KS Satyapal

Dentition plays a crucial role in the fields of forensic science, forensic odontology and anthropology for age and sex estimation. The aim of this study was to determine the degree of sexual dimorphism and age prediction capabilities of permanent dentition using morphometric analysis. Six hundred digital panoramic radiographs (n = 600), belonging to 300 South African Black and 300 South African Indian, aged between 5.00 and 19.99 years were retrospectively examined using a cross-sectional design. The Pearson Correlation Coefficient tests were conducted to determine if a correlation exist between age, sex and each morphometric parameter. “Stepwise Regression Analysis” and “supervised machine learning classification” with a recursive feature elimination and logistic regression were then utilized to parsimoniously prune the morphometric parameters to determine the best models for age and sex estimation, respectively. Males generally displayed larger tooth dimensions than females, with the South African Black population group having larger tooth dimensions than the South African Indian population group. The morphometric parameters of the dentitions showed little sexual dimorphism, with weak correlations less than 0.1, in this study. However, strong correlations between age and the tooth length of the second and third maxillary and mandibular molars (R2 > 0.89) were recorded for the select South African Black and Indian population groups. In conclusion, the sex estimation formulae generated in this study had low performance accuracies for both population groups. However, the age estimation formulae developed from “Stepwise Regression Analysis” in this study were reliable predictors of age, with the tooth and root lengths displaying the best models for age estimation for the South African Black and Indian sample (R2 > 0.9).

牙列在法医科学、法医牙科学和人类学的年龄和性别估计中起着至关重要的作用。本研究的目的是利用形态计量学分析来确定恒牙列性别二态性的程度和年龄预测能力。600张数码全景x线照片(n = 600),属于300名南非黑人和300名南非印第安人,年龄在5.00至19.99岁之间,采用横断面设计回顾性检查。进行Pearson相关系数检验以确定年龄、性别和各形态计量参数之间是否存在相关性。然后利用递归特征消除和逻辑回归的“逐步回归分析”和“监督机器学习分类”来简化形态计量参数,以分别确定年龄和性别估计的最佳模型。男性的牙齿尺寸通常比女性大,南非黑人群体的牙齿尺寸比南非印第安人群体的牙齿尺寸大。在本研究中,牙列的形态计量学参数显示出很少的性别二态性,弱相关小于0.1。然而,年龄与第二、第三上颌磨牙和下颌磨牙的牙长有很强的相关性(R2 >0.89),记录了南非黑人和印度人口群体。总之,本研究中产生的性别估计公式对两个人群的性能准确性都很低。然而,本研究中从“逐步回归分析”中开发的年龄估计公式是年龄的可靠预测因子,其中牙齿和牙根长度显示出南非黑人和印度人样本年龄估计的最佳模型(R2 >0.9)。
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引用次数: 0
Age estimation using vertebral bone spurs; Testing the efficacy of three methods on a European population 使用脊椎骨刺进行年龄估计;在欧洲人群中测试三种方法的有效性
Q3 Medicine Pub Date : 2022-12-01 DOI: 10.1016/j.fsir.2022.100301
Iris F. Sluis , Bjørn P. Bartholdy , Menno L.P. Hoogland , Sarah A. Schrader

Age-at-death estimation is an essential step in both bioarchaeological and forensic studies when human remains are found, as this can also contribute to the identification of the individual. It is critical that age-at-death methods be tested verified in various populations, to obtain the most accurate estimation, making research into new age-at-death methods also imperative. Since osteophyte formation on the vertebral column increases with age, this can be used as a possible method of age-at-death estimation. Snodgrass (2004), Watanabe and Terazawa (2006) and Praneatpolgrang et al. (2019) have tested this method before and have provided promising results. We test the efficacy of Snodgrass (2004), Watanabe and Terazawa (2006), and Praneatpolgrang et al. (2019) on a 19th-century archivally recorded Dutch population. A total of 88 individuals, 40 males, and 48 females were scored for the degree of osteophyte formation on the vertebral column. In addition to testing the three methods above, population-specific regression equations were developed and tested. Accuracy percentages for estimating the age-at-death based on the mean osteophyte score of the entire vertebral column were obtained for all three methods (73.86%, 76.14%, and 72.73%, respectively). In this study, a general pattern of osteophyte formation could be established, which is useful for estimating the age at death. We therefore recommend that this method can be used, cautiously as a means of age-at-death estimation.

在发现人类遗骸时,估计死亡年龄是生物考古和法医研究的一个重要步骤,因为这也有助于个人身份的确定。至关重要的是,死亡年龄方法必须在各种人群中进行测试和验证,以获得最准确的估计,因此研究新的死亡年龄方法也势在必行。由于脊柱骨赘的形成随着年龄的增长而增加,这可以作为估计死亡年龄的一种可能方法。Snodgrass(2004)、Watanabe和Terazawa(2006)以及Praneatpolgrang等人(2019)之前已经测试过这种方法,并提供了有希望的结果。我们测试了Snodgrass (2004), Watanabe和Terazawa(2006)以及Praneatpolgrang等人(2019)对19世纪荷兰人口档案记录的有效性。共有88个人,40名男性和48名女性对脊柱骨赘形成的程度进行了评分。除了测试上述三种方法外,还开发并测试了特定人群的回归方程。三种方法均获得了基于整个脊柱平均骨赘评分估计死亡年龄的准确率(分别为73.86%、76.14%和72.73%)。在这项研究中,骨赘形成的一般模式可以建立,这对估计死亡年龄是有用的。因此,我们建议可以谨慎地使用这种方法作为估计死亡年龄的手段。
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引用次数: 1
Allele frequencies of 15 autosomal STR loci among 540 Myanmarese individuals in Thailand 泰国540名缅甸人15个常染色体STR基因座的等位基因频率
Q3 Medicine Pub Date : 2022-12-01 DOI: 10.1016/j.fsir.2022.100282
Tayawee Romgaew , Sunisa Aobaom

Allele frequencies of 15 autosomal STR loci were established from 540 unrelated Myanmarese individuals using the Thailand Office of Police Forensic Science database. The DNA profiles were provided anonymized with only nationality and gender acknowledged. The allele frequencies were calculated under Hardy-Weinberg equilibrium. The range of allele frequencies was 0.0009–0.5389. Heterozygosity ranged from 0.6204 to 0.8759, probability of identity from 0.0271 to 0.2100, and probability of paternity exclusion from 0.3645 to 0.7579. The information provided in this paper concerns the Myanmarese population in Thailand and could be used for forensic statistical analysis and further individual identification.

利用泰国警察法医科学办公室数据库,从540名无血缘关系的缅甸人中建立了15个常染色体STR位点的等位基因频率。DNA档案是匿名提供的,只承认国籍和性别。在Hardy-Weinberg平衡下计算等位基因频率。等位基因频率范围为0.0009 ~ 0.5389。杂合度范围为0.6204 ~ 0.8759,同一性概率范围为0.0271 ~ 0.2100,父系排除概率范围为0.3645 ~ 0.7579。本文提供的资料涉及在泰国的缅甸人,可用于法医统计分析和进一步的个人鉴定。
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引用次数: 2
期刊
Forensic Science International: Reports
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