While illicit opioids have not been historically significant in Brazil, these numbers have increased in the last few years. This change in the drug scenario is mainly associated with synthetic opioids, a class of new psychoactive substances (NPS). In this context, the present article describes detailed information about the recent cases of synthetic opioids seized in Brazil, especially the nitazenes group.
All the analyses were carried out by the Superintendence of the Technical-Scientific Police - Narcotics Control Center (STSP-NCC) in São Paulo, between July 2022 and April 2023. The synthetic opioids were mainly found in herbal fragments.
Nitazenes, were the most frequent drugs detected in the seizures that took place in the State of São Paulo. There was a total of 140 cases of opioids seizures and 95 % out of those belonging to the nitazene group, while only 5 % consisted of other opioids (morphine and fentanyl). Nitazenes were found 28.6 % isolated and 71.4 % mixed with other active compounds, being MDMB-4en-PINACA the most prevalent (30 % of the samples). Non-nitazenes were found 27.1 % mixed and 72.9 % isolated. Nitazenes and non-nitazene opioids were not found in association in any sample.
This is the first consistent report of nitazene opioids apprehensions in Brazil. Also, as far as we know, it is the first report in which nitazenes were detected in the form of herbal fragments. The effect of smoking a potent opioid together with synthetic cannabinoids is unpredictable and most users cannot be aware of what they are using.
Illegal activities associated with deforestation for the lumber and furniture industries pose significant threats to plant and animal biodiversity, as well as natural resources. Accurate identification of wood sources is vital, yet traditional laboratory techniques often fall short in precisely determining the chemical composition of samples for classification. This study aims to leverage ATR-FTIR spectroscopy alongside machine learning algorithms to construct a robust model for discerning the geographical origins of wood samples from India. By systematically comparing various machine learning classifiers, we address the limitations of subjective visual interpretation and evaluate their accuracy using wood spectral data. Logistic regression emerges as the most effective classifier for distinguishing Eucalyptus (75 % accuracy), Dalbergia (68 % accuracy), and Populus (81.5 % accuracy) species. Through a methodology encompassing data pre-processing, classifier selection, and performance evaluation, this research offers promising tools for combating challenges posed by illegal wood trafficking and transportation. The outcomes hold significant potential for enhancing wildlife crime prevention efforts by facilitating the tracing illicit timber sources, apprehension of perpetrators, and implementation of preventive measures.

