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Non-destructive sampling of poison frogs for toxin analysis in forensic casework 法医案件中毒蛙毒素分析的无损取样
Q3 Medicine Pub Date : 2025-04-17 DOI: 10.1016/j.fsir.2025.100414
Irene Kuiper, Aleksandar Dragutinovic, Leo Peschier, Rene de Bruyn
Poison frogs is the common name for several genera of frogs which occur naturally in Central- and South-America, Australia and Madagascar and which contain a wide variety of toxins. Their colourful appearance and minute size resulted in their extraction from their natural habitat for illegal trade, threatening population sizes. In order to fight this illegal trade, the poison frog’s ability to excrete environmentally acquired toxins via their skin can be used in criminal investigations. Since the frogs are not able to produce the toxins de novo, these alkaloid toxins have ultimately originated from their environment and are excreted through the skin, especially when stressed. Due to the reliance on a toxin-containing food source, we show that the presence of toxins in poison frogs can be used to distinguish between captive breeding and wild-capture in actual forensic case work. We describe the application of a gas chromatography-mass-spectrometry (GC-MS) analysis on non-destructively derived samples from living frogs in five seizures, the biological interpretation of presence and absence of toxins and the criminalistic interpretation of the findings given propositions of both the prosecutor and the defendant.
毒蛙是几种天然存在于中南美洲、澳大利亚和马达加斯加的蛙类的统称,它们含有各种各样的毒素。它们鲜艳的外表和微小的体型导致它们从自然栖息地被非法交易,威胁到它们的种群规模。为了打击这种非法贸易,毒蛙通过皮肤分泌环境获得毒素的能力可以用于刑事调查。由于青蛙不能从头产生毒素,这些生物碱毒素最终来自它们的环境,并通过皮肤排出,尤其是在受到压力的时候。由于依赖于含毒素的食物来源,我们表明毒素在毒蛙中的存在可以用来区分圈养繁殖和野生捕获在实际的法医案件工作。我们描述了气相色谱-质谱(GC-MS)分析在五次缉获中对活青蛙的非破坏性衍生样品的应用,毒素存在和不存在的生物学解释以及检察官和被告给出的命题的调查结果的刑事解释。
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引用次数: 0
Species identification of avian feathers in Japanese Habouki using feather morphological and molecular testing 利用羽毛形态学和分子检测对日本Habouki鸟类羽毛进行种类鉴定
Q3 Medicine Pub Date : 2025-04-11 DOI: 10.1016/j.fsir.2025.100415
Nana Ushine , Isao Nishiumi , Higuchi Aki , Aki Tanaka , Ayano Mori , Nanami Tsuchiya , Shin-ichi Hayama
Habouki is a tool used in Japanese tea ceremonies consisting of a bundle of feathers from birds of prey and waterfowl. Habouki often include feathers from avian species that are legally protected. In this study, we examined three types of Habouki (Zabaki, Tsukamibane, and Mitsubane) suspected of containing feathers from legally protected species and conducted species identification through feather morphological examination and molecular analysis. Morphological examinations and molecular biological analyses targeting cytochrome c oxidase subunit 1 region were conducted using the barbs of Habouki feathers. Genetic analysis revealed that Zabaki contained feathers from Aquila chrysaetos (genetic difference between Habouki feather and the control sample; 0.02 %), Tsukamibane contained Cygnus columbianus (0.16 %), and Mitsubane contained Ciconia boyciana (0.05 %). In the morphological examinations based on shape, color, and size, the Zabaki feather was presumed to be the rectrices of the Golden Eagle (Aquila chrysaetos), the Tsukamibane feather was the tertials of Whooper Swan (Cygnus cygnus) and Tundra Swan (Cygnus columbianus), and the Mitsubane feather was the secondary and tertial feathers of the Japanese White Stork (Ciconia boyciana). Habouki are currently not being produced. To safeguard the continuity of Japanese tea ceremony culture, it is crucial to protect Habouki and prevent illegal activities such as poaching. When determining whether feathers belong to rare species, it is recommended to conduct feather morphological examinations rather than molecular biological examinations, which destroy Habouki.
Habouki是日本茶道中使用的一种工具,由一束猛禽和水禽的羽毛组成。Habouki通常包括受法律保护的鸟类的羽毛。本研究对三种疑似含有法律保护物种羽毛的鸟(Zabaki、Tsukamibane和mitsubishi)进行了检测,并通过羽毛形态学检查和分子分析进行了物种鉴定。利用Habouki羽倒刺进行了细胞色素c氧化酶亚基1区的形态学检查和分子生物学分析。遗传分析表明,Zabaki含有金凤蝶羽毛(Habouki羽毛与对照样本遗传差异);冢毒班含哥伦比亚Cygnus(0.16 %),三菱班含白鹤Cygnus boyciana(0.05 %)。根据形状、颜色和大小的形态学检查,认为扎崎羽是金鹰(Aquila chrysaetos)的羽毛,冢冢羽是大天鹅(Cygnus Cygnus)和苔原天鹅(Cygnus columbianus)的三甲羽毛,三菱羽是日本白鹳(Ciconia boyciana)的二甲羽毛和三甲羽毛。Habouki目前还没有生产。为了维护日本茶道文化的延续性,保护好Habouki,防止偷猎等非法活动至关重要。在确定羽毛是否属于稀有物种时,建议进行羽毛形态学检查,而不是分子生物学检查,因为分子生物学检查会破坏Habouki。
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引用次数: 0
A proof-of-concept study into turmeric spice as an improvised fluorescent latent fingermark detection powder for limited resource jurisdictions 姜黄香料作为一种临时荧光潜在手印检测粉末的概念验证研究
Q3 Medicine Pub Date : 2025-03-25 DOI: 10.1016/j.fsir.2025.100413
Thais Lópes , Maame Gyamfuah Buckman , Georgina Sauzier , Rodrigo M. Barros , Simon W. Lewis
Latent fingermarks are a crucial form of physical evidence for crime scene investigations; however, limited-resource jurisdictions, such as some states in Brazil, face challenges in identifying fingermarks due to lower access to commercial fingermark developers. The study of unconventional and alternative techniques for fingermark detection that are low-cost, easily available, and sustainable in line with the UN SDGs presents great value for under-resourced jurisdictions. Household items and easily available materials such as spices fit perfectly in such contexts as improvised fingermark powders. Turmeric is a globally accessible culinary spice which contains high levels of the fluorescent compound curcumin. This research reports for the first time the application of turmeric spice powder as fluorescent dusting powder for latent fingermark detection. Turmeric spice powders from different sources were evaluated for their performance as dusting powders and were subsequently characterised by optical microscopy, Fourier transform infrared spectroscopy, and fluorescence spectrophotometry. All turmeric powders exhibited high fluorescence intensities and were demonstrated to be suitable as fluorescent fingermark powders without further processing, though specimens with homogeneous particle size distribution and pure turmeric composition performed better. These preliminary results indicate that turmeric is a suitable fingermark powder without further modification and is a potential alternative to commercial powders for jurisdictions with limited resources.
潜在的手印是犯罪现场调查的重要物证。然而,资源有限的司法管辖区,如巴西的一些州,在识别指纹方面面临着挑战,因为很难接触到商业指纹开发商。研究低成本、容易获得、可持续的符合联合国可持续发展目标的非常规和替代指纹检测技术,对资源不足的司法管辖区具有巨大价值。家庭用品和容易获得的材料,如香料,非常适合这种情况下,如临时手印粉。姜黄是一种全球通用的烹饪香料,它含有高水平的荧光化合物姜黄素。本研究首次报道了姜黄香料粉作为荧光粉尘粉在潜在手印检测中的应用。研究了不同来源的姜黄香料粉末的除尘性能,并用光学显微镜、傅里叶变换红外光谱和荧光分光光度法对其进行了表征。所有姜黄粉均表现出高荧光强度,无需进一步处理即可作为荧光手印粉,但粒度分布均匀且成分纯的姜黄粉表现更好。这些初步结果表明,姜黄是一种合适的手印粉,无需进一步改性,在资源有限的司法管辖区是一种潜在的商业粉末替代品。
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引用次数: 0
Establishing a system of professional self-government of forensic scientists in Ukraine 在乌克兰建立法医专家专业自治制度
Q3 Medicine Pub Date : 2025-03-08 DOI: 10.1016/j.fsir.2025.100412
Nataliia Martynenko
The article highlights the experience of establishing and operation of the system of professional self-government of forensic scientists in the UK and France. The relevance of the issues studied in the article is due to the need to ensure strategic self-governance in the field of forensic science in Ukraine, which will involve all the main stakeholders. It is emphasized that there is a current need to reform forensic science activity. The author proposes a model of professional self-government of forensic scientists which will take into account: the system of subjects of forensic science activity operating in the state; the possibility of ensuring effective exercise of professional rights and protection of professional interests of forensic scientists, whether public or private, etc. The article substantiates the expediency of establishing the following organizational forms of self-government of forensic scientists: working groups of forensic scientists by type of forensic examination; the Council of Forensic Scientists of Ukraine; and the Congress of Forensic Scientists of Ukraine. It is proposed to name the professional self-governing organization that will unite all forensic scientists of Ukraine – the Forensic Science Academy of Ukraine. From this perspective, the author proposes amendments to the current Law of Ukraine “On Forensic Expertise”. The author concludes that organizations which exercise professional self-government of forensic scientists should lobby for the interests of their profession and perform a wide range of public functions.
本文着重介绍了英法两国法医学专家职业自治制度的建立和运行经验。本文所研究问题的相关性是由于需要确保乌克兰法医科学领域的战略自治,这将涉及所有主要利益攸关方。报告强调,目前有必要改革法医科学活动。笔者提出了一种法医学专家职业自治的模式,该模式考虑到:司法科学活动主体制度在国家范围内运作;确保公共或私人法医科学家有效行使专业权利和保护专业利益的可能性等。文章论证了建立法医学工作者自治组织形式的可行性:按鉴定类型组成法医学工作者工作小组;乌克兰法医科学家理事会;以及乌克兰法医科学家大会。建议将团结乌克兰所有法医科学家的专业自治组织命名为乌克兰法医科学院。从这一角度出发,笔者提出了对乌克兰现行《司法鉴定法》的修改建议。法医学专家职业自治组织应当为法医学专家的职业利益进行游说,并履行广泛的公共职能。
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引用次数: 0
Enhancing forensic sex identification through AI-based analysis of the foramen magnum 通过基于人工智能的枕骨大孔分析增强法医性别鉴定
Q3 Medicine Pub Date : 2025-02-07 DOI: 10.1016/j.fsir.2025.100411
Sirinart Chomean , Natipong Chatthai , Napakorn Sangchay , Chollanot Kaset
Sex estimation from skeletal remains is an essential task in forensic anthropology. Traditional morphological analysis, while effective, can be time-consuming and subject to inter-observer variability. This study evaluates artificial intelligence (AI)-based methods, specifically object detection and instance segmentation, for sex estimation using the foramen magnum (FM). A total of 600 adult dry skull images (300 males, 300 females) were labeled and augmented to create a dataset of 2280 images, which was split into training (92 %), validation (5 %), and test (3 %) sets. The models were trained using Roboflow and assessed based on sensitivity, specificity, accuracy, positive predictive value (PPV), and negative predictive value (NPV), with additional validation performed on 30 independent skulls. The object detection model demonstrated strong performance, achieving high precision (95.0 %) and recall (100.0 %) in training, with precision values of 93.0 % and 89.0 % in validation and test sets, respectively, while maintaining 100.0 % recall across datasets. In the independent test set, the model achieved 75.0 %specificity. The instance segmentation method yielded lower performance, with specificity of 68.75 %. The overall accuracy of the object detection method was 65.68 % (95 % CI: 46.19 % - 81.64 %), outperforming the instance segmentation method, which achieved an accuracy of 62.69 % (95 % CI: 43.22 % - 79.55 %). Although AI-based methods, particularly object detection, show potential for forensic sex estimation from foramen magnum, the results indicate that their accuracy remains lower than traditional morphometric approaches. Future research should focus on integrating additional cranial features and expanding the training dataset to enhance model reliability and generalizability.
骨骸性别鉴定是法医人类学的一项重要工作。传统的形态分析虽然有效,但可能耗时且受观察者之间差异的影响。本研究评估了基于人工智能(AI)的方法,特别是对象检测和实例分割,用于使用枕骨大孔(FM)进行性别估计。总共600张成人干颅骨图像(300张男性,300张女性)被标记和增强,创建了2280张图像的数据集,该数据集分为训练集(92张 %),验证集(5张 %)和测试集(3张 %)。使用Roboflow对模型进行训练,并根据敏感性、特异性、准确性、阳性预测值(PPV)和阴性预测值(NPV)进行评估,并在30个独立颅骨上进行额外验证。目标检测模型表现出较强的性能,在训练中实现了较高的准确率(95.0 %)和召回率(100.0 %),在验证集和测试集上的准确率分别为93.0 %和89.0 %,同时在数据集上保持了100.0 %的召回率。在独立测试集中,该模型的特异性达到了75.0 %。实例分割方法的效果较差,特异性为68.75 %。目标检测方法的总体准确率为65.68 %(95 % CI: 46.19 % ~ 81.64 %),优于实例分割方法,后者的准确率为62.69 %(95 % CI: 43.22 % ~ 79.55 %)。尽管基于人工智能的方法,特别是物体检测,显示出从枕骨大孔进行法医性别估计的潜力,但结果表明,它们的准确性仍然低于传统的形态测量方法。未来的研究应集中于整合额外的颅骨特征和扩展训练数据集,以提高模型的可靠性和泛化性。
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引用次数: 0
Firearm fatalities in Dammam: A forensic retrospective study 达曼的枪支死亡:一项法医回顾性研究
Q3 Medicine Pub Date : 2025-02-05 DOI: 10.1016/j.fsir.2025.100410
Magdy Kharoshah , Maram Aabdulghani AlFarayedhi , Abdullah AlBouijan , Noua AlOtaibi , AbdulRahman Waheed AlDossary , Ibrahim AlAboudi , Sahar Issa

Background

Numerous nations have released studies on lethal firearm injuries. Nonetheless, there has been little documentation of their occurrence and pattern in various parts of Saudi Arabia and other Arab Countries.

Methods

The present study was conducted to investigate fatal firearm injuries in Dammam, Saudi Arabia, during 2013–2023. All investigated victims were referred to the mortuary of the Forensic Medicine Department, Dammam.

Results

The study investigated all firearm deaths in Dammam. Most of the victims were Saudi Nationals. Homicidal victims (N = 88) surpassed the suicidal cases (N = 24). Rifled weapons were the most common weapon used in both groups. Head wounds were much more common in suicides (70.8 %) compared to homicides (34.1 %) (p = 0.001). Toxicological findings confirmed more Cannabis in homicide cases and more Ethanol in suicide cases.

Conclusions

The current findings were contradictory to the pattern seen in other countries where suicides were the predominant group.
许多国家已经发布了关于致命火器伤害的研究报告。然而,在沙特阿拉伯和其他阿拉伯国家的不同地区,几乎没有关于其发生和模式的文件。方法对2013-2023年沙特阿拉伯达曼地区的致命火器伤害进行调查。所有被调查的受害者都被送到达曼法医部的太平间。结果该研究调查了达曼所有枪支死亡事件。大多数遇难者是沙特国民。杀人者(N = 88人)超过了自杀者(N = 24人)。膛线武器是两组人中最常用的武器。头部受伤在自杀(70.8% %)中比在他杀(34.1% %)中更为常见(p = 0.001)。毒理学调查结果证实,大麻在杀人案件中占比更高,酒精在自杀案件中占比更高。结论:目前的研究结果与其他国家的模式相矛盾,在其他国家,自杀是主要群体。
{"title":"Firearm fatalities in Dammam: A forensic retrospective study","authors":"Magdy Kharoshah ,&nbsp;Maram Aabdulghani AlFarayedhi ,&nbsp;Abdullah AlBouijan ,&nbsp;Noua AlOtaibi ,&nbsp;AbdulRahman Waheed AlDossary ,&nbsp;Ibrahim AlAboudi ,&nbsp;Sahar Issa","doi":"10.1016/j.fsir.2025.100410","DOIUrl":"10.1016/j.fsir.2025.100410","url":null,"abstract":"<div><h3>Background</h3><div>Numerous nations have released studies on lethal firearm injuries. Nonetheless, there has been little documentation of their occurrence and pattern in various parts of Saudi Arabia and other Arab Countries.</div></div><div><h3>Methods</h3><div>The present study was conducted to investigate fatal firearm injuries in Dammam, Saudi Arabia, during 2013–2023. All investigated victims were referred to the mortuary of the Forensic Medicine Department, Dammam.</div></div><div><h3>Results</h3><div>The study investigated all firearm deaths in Dammam. Most of the victims were Saudi Nationals. Homicidal victims (N = 88) surpassed the suicidal cases (N = 24). Rifled weapons were the most common weapon used in both groups. Head wounds were much more common in suicides (70.8 %) compared to homicides (34.1 %) (p = 0.001). Toxicological findings confirmed more Cannabis in homicide cases and more Ethanol in suicide cases.</div></div><div><h3>Conclusions</h3><div>The current findings were contradictory to the pattern seen in other countries where suicides were the predominant group.</div></div>","PeriodicalId":36331,"journal":{"name":"Forensic Science International: Reports","volume":"11 ","pages":"Article 100410"},"PeriodicalIF":0.0,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143377828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fatal poisonings in Nordic countries in 2022 among people who use drugs 2022年北欧国家吸毒人群的致命中毒
Q3 Medicine Pub Date : 2025-01-27 DOI: 10.1016/j.fsir.2025.100408
Pirkko Kriikku , Hilde Marie E. Edvardsen , Gunilla Thelander , Svava Thordardottir , Charlotte Uggerhøj Andersen , Ilkka Ojanperä , Anna K. Jönsson , Joachim Frost , Simon Kjær Hermansen , Gerd J.M. Delaveris , Kirsten Wiese Simonsen
The present study is a survey of fatal poisonings occurring in 2022 among people who use drugs (PWUD) in the Nordic countries. This is the eighth report in a series of studies on PWUD conducted about every fifth year since 1984 by a working group representing Denmark, Finland, Iceland, Norway and Sweden.Data on the number of deaths, gender, age, place of death, main intoxicant, and drugs detected in blood were recorded. National data were compared between the Nordic countries as well as with the earlier studies. The death rate (number of deaths per 100,000 inhabitants) among PWUD in 2022 was highest in Norway (8.03), followed by Iceland (7.20) and Finland (5.95), and lowest in Denmark (5.09). This rate increased in all countries compared to 2017, except in Sweden, which saw a decrease from 6.46 to 5.91. The change was only statistically significant in Norway. Most deaths occurred among men, with women accounting for 16–23 %. The median age at the time of death among PWUD was 40–43 years in Denmark, Norway and Sweden, while it was about ten years younger in Finland and Iceland (median age 33 years). Opioids were the main cause of PWUD death in all countries. The proportion of opioid deaths amounted to 73–89 % and was lowest in Denmark and highest in Iceland. New psychoactive substances (NPS) were sporadically detected in all countries but were rarely the main intoxicant. The largest diversity of NPS was detected in Finland and Sweden.
本研究是对2022年北欧国家吸毒者(PWUD)中发生的致命中毒的调查。这是由一个代表丹麦、芬兰、冰岛、挪威和瑞典的工作组自1984年以来每隔五年进行的一系列关于和平与发展问题的研究中的第八份报告。记录了有关死亡人数、性别、年龄、死亡地点、主要麻醉品和血液中检测到的药物的数据。北欧国家之间的国家数据以及与早期研究的数据进行了比较。2022年,贫困地区居民的死亡率(每10万居民死亡人数)最高的是挪威(8.03),其次是冰岛(7.20)和芬兰(5.95),最低的是丹麦(5.09)。与2017年相比,所有国家的这一比率都有所上升,但瑞典从6.46下降到5.91。这一变化仅在挪威有统计学意义。大多数死亡发生在男性中,女性占16 - 23% %。丹麦、挪威和瑞典的PWUD患者死亡时的中位年龄为40-43岁,而芬兰和冰岛的中位年龄约年轻10岁(中位年龄33岁)。阿片类药物是所有国家puwud死亡的主要原因。阿片类药物死亡比例为73-89 %,丹麦最低,冰岛最高。在所有国家都偶尔发现新的精神活性物质(NPS),但很少是主要的麻醉剂。芬兰和瑞典的NPS多样性最大。
{"title":"Fatal poisonings in Nordic countries in 2022 among people who use drugs","authors":"Pirkko Kriikku ,&nbsp;Hilde Marie E. Edvardsen ,&nbsp;Gunilla Thelander ,&nbsp;Svava Thordardottir ,&nbsp;Charlotte Uggerhøj Andersen ,&nbsp;Ilkka Ojanperä ,&nbsp;Anna K. Jönsson ,&nbsp;Joachim Frost ,&nbsp;Simon Kjær Hermansen ,&nbsp;Gerd J.M. Delaveris ,&nbsp;Kirsten Wiese Simonsen","doi":"10.1016/j.fsir.2025.100408","DOIUrl":"10.1016/j.fsir.2025.100408","url":null,"abstract":"<div><div>The present study is a survey of fatal poisonings occurring in 2022 among people who use drugs (PWUD) in the Nordic countries. This is the eighth report in a series of studies on PWUD conducted about every fifth year since 1984 by a working group representing Denmark, Finland, Iceland, Norway and Sweden.Data on the number of deaths, gender, age, place of death, main intoxicant, and drugs detected in blood were recorded. National data were compared between the Nordic countries as well as with the earlier studies. The death rate (number of deaths per 100,000 inhabitants) among PWUD in 2022 was highest in Norway (8.03), followed by Iceland (7.20) and Finland (5.95), and lowest in Denmark (5.09). This rate increased in all countries compared to 2017, except in Sweden, which saw a decrease from 6.46 to 5.91. The change was only statistically significant in Norway. Most deaths occurred among men, with women accounting for 16–23 %. The median age at the time of death among PWUD was 40–43 years in Denmark, Norway and Sweden, while it was about ten years younger in Finland and Iceland (median age 33 years). Opioids were the main cause of PWUD death in all countries. The proportion of opioid deaths amounted to 73–89 % and was lowest in Denmark and highest in Iceland. New psychoactive substances (NPS) were sporadically detected in all countries but were rarely the main intoxicant. The largest diversity of NPS was detected in Finland and Sweden.</div></div>","PeriodicalId":36331,"journal":{"name":"Forensic Science International: Reports","volume":"11 ","pages":"Article 100408"},"PeriodicalIF":0.0,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143136034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PSA is not suitable as a reliable marker for seminal fluid in rectal samples collected post-mortem PSA不适合作为死后直肠精液样本的可靠标记物
Q3 Medicine Pub Date : 2025-01-26 DOI: 10.1016/j.fsir.2025.100409
Corine Müller, Elie Pascolo Tièche, Martin Zieger
Prostate-specific antigen (PSA) tests are used in forensic examinations of sexual offences to indicate the presence of seminal fluid. Based on a retrospective analysis of 484 forensic samples collected in sexual assault cases, we observed a significant enrichment of potentially misleading tests for seminal fluid, for samples collected post-mortem. Reduced reliability of PSA testing for the indication of the presence of ejaculate in samples collected post-mortem has already been reported previously. However, previous studies either included only a small number of rectal samples, particularly from female cadavers, or were based on vaginal swabs. In our study, 34 female and 67 male rectal swab samples collected post-mortem were analysed. The rate of positive SERATEC® PSA Semiquant tests was 33 % for women and 67 % for men. Using male specific qPCR, male DNA was detected in only one of the female samples, indicating a high false-positive rate for both sexes when using SERATEC® PSA Semiquant tests as indicators for the presence of seminal liquid post mortem. Different degrees of decomposition showed no significant correlation with the PSA positivity rate. As expected, a significant correlation between the sex of the deceased individuals and the PSA test result could be demonstrated. The study demonstrates the very limited probative value of PSA as a marker for seminal fluid post mortem.
前列腺特异性抗原(PSA)测试用于性犯罪的法医检查,以表明精液的存在。基于对在性侵犯案件中收集的484个法医样本的回顾性分析,我们观察到,在死后收集的样本中,精液的检测可能会有很大的误导性。PSA检测在死后采集的样本中是否存在射精的可靠性降低,此前已有报道。然而,以前的研究要么只包括少数直肠样本,特别是来自女性尸体的样本,要么是基于阴道拭子。在我们的研究中,分析了34名女性和67名男性在死后收集的直肠拭子样本。SERATEC®PSA半定量检测阳性率女性为33% %,男性为67% %。使用男性特异性qPCR,仅在一个女性样本中检测到男性DNA,这表明当使用SERATEC®PSA Semiquant测试作为死后精液存在的指标时,两性的假阳性率都很高。不同分解程度与PSA阳性率无显著相关性。正如预期的那样,死亡个体的性别和PSA检测结果之间存在显著的相关性。该研究表明PSA作为死后精液标记物的证明价值非常有限。
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引用次数: 0
Necrophilia a case report from Mozambique 莫桑比克报告一例恋尸癖
Q3 Medicine Pub Date : 2025-01-22 DOI: 10.1016/j.fsir.2025.100407
Katia Robledo Querol , Bonifacio Rodrigues Cebola , Susanna Caminada , Manuel González Rodríguez , Enani Rogerio Uamusse , Nolton Francisco Jeque , Justin Stebbing , Samantha Lundringan , Damiano Pizzol , Lee Smith
Necrophilia is a paraphilia in which the primary source of pleasure comes from having sex with, or sexually abusing the dead. The etiology is unknown and includes multiple social, environmental and contextual factors. Its prevalence is probably underestimated, and, especially in low-income settings, the reporting is limited. We report on a 17-year-old female cadaver characterized by generalized coldness, fixed lividity in the posterior plane, cadaveric relaxation phase, presence of a green abdominal stain in the right iliac fossa and chromatic phase of putrefaction; exhumed and sexually violated after burial. We also provide a review of the existing literature.
恋尸癖是一种性癖好,其中快乐的主要来源来自与死者发生性关系,或对死者进行性虐待。病因不明,包括多种社会、环境和背景因素。它的流行可能被低估了,特别是在低收入环境中,报告是有限的。我们报告一例17岁的女性尸体,其特征是全身发冷,后平面固定积液,尸体松弛期,右侧髂窝腹部出现绿色染色和腐色期;被挖出来,埋葬后遭到性侵犯。我们也提供了现有的文献综述。
{"title":"Necrophilia a case report from Mozambique","authors":"Katia Robledo Querol ,&nbsp;Bonifacio Rodrigues Cebola ,&nbsp;Susanna Caminada ,&nbsp;Manuel González Rodríguez ,&nbsp;Enani Rogerio Uamusse ,&nbsp;Nolton Francisco Jeque ,&nbsp;Justin Stebbing ,&nbsp;Samantha Lundringan ,&nbsp;Damiano Pizzol ,&nbsp;Lee Smith","doi":"10.1016/j.fsir.2025.100407","DOIUrl":"10.1016/j.fsir.2025.100407","url":null,"abstract":"<div><div>Necrophilia is a paraphilia in which the primary source of pleasure comes from having sex with, or sexually abusing the dead. The etiology is unknown and includes multiple social, environmental and contextual factors. Its prevalence is probably underestimated, and, especially in low-income settings, the reporting is limited. We report on a 17-year-old female cadaver characterized by generalized coldness, fixed lividity in the posterior plane, cadaveric relaxation phase, presence of a green abdominal stain in the right iliac fossa and chromatic phase of putrefaction; exhumed and sexually violated after burial. We also provide a review of the existing literature.</div></div>","PeriodicalId":36331,"journal":{"name":"Forensic Science International: Reports","volume":"11 ","pages":"Article 100407"},"PeriodicalIF":0.0,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143136171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of latent tuberculosis and mycobacterial infections in medicolegal cases with pleural adhesions: An observational study 医学上的胸膜粘连病例中潜伏结核和分枝杆菌感染的患病率:一项观察性研究
Q3 Medicine Pub Date : 2025-01-17 DOI: 10.1016/j.fsir.2025.100406
Jayanthi Yadav , Ujjawal Khurana , Shubham Richariya , Shashank Purwar , Sangita Moirangthem , Johann Aibantyllilang Blah

Objective and Background

Pleural adhesions, fibrous bands between pleural layers, are common in autopsies and often associated with Tuberculosis (TB). This study aims to determine the prevalence of latent TB and mycobacterial infections in medicolegal cases with pleural adhesions. The focus is on various diagnostic approaches and implications of the study for TB management in a high-burden setting like India.

Materials and Methods

The observational study spanned two years, involving 743 autopsies at AIIMS Bhopal. Tissue samples from 82 cases with pleural adhesions were analyzed after obtaining consent and a detailed history. Diagnostic methods, including direct smear microscopy, Mycobacteria Growth Indicator (MGIT), Lowenstein–Jensen (LJ) media, and PCR, were employed.

Observation

Of 164 cases with pleural adhesions, 15 (18.29 %) were positive for Mycobacterium, including 11 MTB and 4 NTM cases. Diagnostic methods revealed the challenges in detecting latent TB. Incidental diagnoses were prevalent, emphasizing the need for heightened awareness. Advanced techniques (MGIT, LJ, PCR) improved detection rates. The study highlights latent TB's impact in India, suggesting the importance of research, surveillance, and interventions for effective TB control. Addressing latent TB becomes crucial in global eradication efforts.

Conclusion

The study emphasizes India's TB burden, with pleural adhesions acting as clinical markers. Incidental diagnoses and the role of latent TB in the population underscore the need for enhanced research and diagnostic strategies. Diagnostic challenges, including limited symptoms, necessitate advanced techniques. The study discusses the multifaceted challenge of latent TB diagnosis and the importance of interventions.
目的和背景胸膜粘连,即胸膜层之间的纤维带,在尸检中很常见,通常与肺结核(TB)有关。本研究旨在确定医学上胸膜粘连病例中潜伏性结核和分枝杆菌感染的患病率。重点是各种诊断方法和该研究对印度等高负担国家结核病管理的影响。材料和方法这项观察性研究历时两年,涉及博帕尔医学研究所的743例尸体解剖。我们对82例胸膜粘连患者的组织样本进行了分析。诊断方法包括直接涂片镜检、分枝杆菌生长指示剂(MGIT)、Lowenstein-Jensen培养基(LJ)和PCR。164例胸膜粘连患者中分枝杆菌阳性15例(18.29 %),其中MTB 11例,NTM 4例。诊断方法揭示了检测潜伏性结核病的挑战。偶然诊断很普遍,强调需要提高认识。先进的技术(MGIT、LJ、PCR)提高了检出率。这项研究突出了潜伏性结核病在印度的影响,表明了研究、监测和干预措施对有效控制结核病的重要性。处理潜伏性结核病在全球根除工作中至关重要。结论该研究强调印度的结核病负担,胸膜粘连可作为临床标志。偶然诊断和潜伏性结核病在人群中的作用强调了加强研究和诊断策略的必要性。诊断方面的挑战,包括有限的症状,需要先进的技术。该研究讨论了潜伏性结核病诊断的多方面挑战和干预措施的重要性。
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引用次数: 0
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Forensic Science International: Reports
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