中华放射医学与防护杂志最新文献

{"title":"Current status of the application of radiodiagnosis and radiotherapy resources in Huai'an City in 2020","authors":"B. Huo, Z. Xu, X. Chen","doi":"10.3760/cma.j.issn.0254-5098.2021.07.006","DOIUrl":"https://doi.org/10.3760/cma.j.issn.0254-5098.2021.07.006","url":null,"abstract":"Objective: To investigate the current status of the radiodiagnosis and radiotherapy resources and medical exposure frequencies in Huai'an City. Methods: According to the monitoring data in the \" Radiological Health Information Management Platform of Jiangsu Province\" in 2020, a descriptive analysis was conducted on the personnel, equipment, and exposure frequencies in the institutes engaged in radiation-based diagnosis and treatment in Huai'an. Results: A total of 181 hospitals were investigated in 2020, including 7 tertiary hospitals(3.9%), 24 secondary hospitals(13.3%), 126 primary hospitals(69.6%), and 24 ungraded hospitals(13.3%). There were 1 397 radiation workers, including 948 males and 449 females, and 459 pieces of radiation equipment, including 420 for radio diagnosis, 13 for radiotherapy, 4 for nuclear medicine, and 22 for interventional radiology. The hospitals of different grades greatly differed in the number of radiation workers and equipment. There were 80.1, 20.9, 2.2, and 2.0 radiation workers and 15.7, 5.5, 1.4, and 1.6 pieces of radiation equipment in the tertiary hospitals, secondary hospitals, primary hospitals, and ungraded hospitals, respectively on average. There were 2 903 246, 27 648, 8 087, and 17 874 receiving radiodiagnosis, radiotherapy, nuclear medicine, and interventional radiology, respectively in 2020. The medical exposure frequencies in the whole city were calculated to be 599.50 per 1 000 population, including 334.59 treated with conventional X-rays, 239.82 receiving CT scan, 14.18 for breast and dentistry, 3.62 receiving interventional radiology, 5.61 treated with radiotherapy, and 1.69 receiving nuclear medicine. Conclusions: The radiodiagnosis and radiotherapy resources are unbalanced in the hospitals of different grades in Huai'an City. Therefore, it is necessary to pay more attention to the reasonable allocation of medical resources. Meanwhile, radiation workers in secondary hospitals may be more prone to job burnout. Facing the normalization of the prevention and control of COVID-19 epidemic, the supervision and management of radiological health should be strengthened to ensure the legitimacy of radiological diagnosis and radiotherapy and theoptimization of protection. The frequencies of medical exposure are consistent with the local economic level. To analyze the differences in medical exposure frequencies and predict the developmental trends in different regions, it is necessary to establish a more accurate prediction model. Copyright © 2021 by the Chinese Medical Association.","PeriodicalId":36403,"journal":{"name":"中华放射医学与防护杂志","volume":"6 1","pages":"509-513"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88914822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Infection control status of novel coronavirus pneumonia and radiation safety at CT workplace","authors":"W. Tang, L. Mei, Y. Xia, K. Ma, G. Sun, L. Tang","doi":"10.3760/cma.j.issn.0254-5098.2021.07.007","DOIUrl":"https://doi.org/10.3760/cma.j.issn.0254-5098.2021.07.007","url":null,"abstract":"CT is an important imaging tool for the diagnosis of novel coronavirus pneumonia (COVID-19), therefore, it's necessary to strictly control the disinfection of CT workplace and equipment and biosafety to avoid the place from becoming a potential infection source and to reduce the risk of infection of patients and radiological staff. It is also necessary to reduce the CT scan dose to minimize the radiation hazards on patients under the premise of ensuring the CT image quality and diagnostic efficiency. Based on the survey that novel coronavirus residues after disinfection at some CT workplace in domestic and overseas and the application of low-dose CT scan in diagnosis of COVID-19, as well as the current situation of radiological protection management in emergency hospital, this paper summarizes and proposes suggestions on infection control and radiological protection for CT workplace to strengthen the defense line of COVID-19 prevention and control. Copyright © 2021 by the Chinese Medical Association.","PeriodicalId":36403,"journal":{"name":"中华放射医学与防护杂志","volume":"17 1","pages":"514-518"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75012934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The application value of low-dose CT scan in pregnant women with COVID-19","authors":"Liang Li, Li Wang, Feifei Zeng, F. Liu, Zhoufeng Peng, Baojun Xie, Changsheng Liu, Y. Zha","doi":"10.3760/CMA.J.ISSN.0254-5098.2020.05.001","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-5098.2020.05.001","url":null,"abstract":"","PeriodicalId":36403,"journal":{"name":"中华放射医学与防护杂志","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84472756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility study of using fluoroscopy time as warning indicator for radiation dose in cardiovascular interventions","authors":"Hai-Wen Ding, Yongchun Wang","doi":"10.3760/CMA.J.ISSN.0254-5098.2020.03.014","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-5098.2020.03.014","url":null,"abstract":"Objective \u0000To collect the date of radiation dose in reference air kerma(AK) and dose-area product (DAP) values in order to evaluate the feasibility of fluoroscopy time as a monitoring and warning indicator of radiation exposure in cardiovascular interventions. \u0000 \u0000 \u0000Methods \u0000The study conducted a retrospective analysis of 736 patients who underwent coronary angiography(CAG)and percutaneous coronary intervention(PCI)from November 2016 to January 2018 in Shanghai Changhai Hospital. Based on the imaging equipments(a Siemens Ceiling system and a Siemens Biplane system)and cardiovascular interventions(CAG and PCI), the fluoroscopy time, AK values and DAP values were collected. The correlation of the radiation dose and fluoroscopy time was analyzed using Spearman correlation statistics. \u0000 \u0000 \u0000Results \u0000The mean values of fluoroscopy time, fluoroscopy AK, total AK, fluoroscopy DAP and total DAP were(8.9±7.8)min, (472±474), (703±595)mGy, (4 578±4 085)and(6 253±4 938)μGy·m2 for Ceiling system and(8.6±7.3)min, (510±509), (733±614)mGy, (4 255±3 781)and (5 681±4 432)μGy·m2 for Biplane system, respectively. The mean values of CAG and PCI fluoroscopy time were(2.4±0.9)and(15.7±4.9)min, respectively.The ratio of fluoroscopy radiation dose (AK and DAP) to total dose was 74% and 78% in PCI procedures. There was a strongly correlation between fluoroscopy time and total AK (r=0.822) or total DAP (r=0.844) in cardiovascular interventions (P<0.001). \u0000 \u0000 \u0000Conclusions \u0000The radiation dose of fluoroscopy acquisition is the main source of overall radiation dose in cardiovascular interventions. Radiation dose is expected to increase as fluoroscopy time increases.The fluoroscopy timer as a protective tool of radiation exposure has a good reference and warning value in the clinical application of cardiovascular interventions. \u0000 \u0000 \u0000Key words: \u0000Cardiovascular intervention; Radiation dose; Fluoroscopy time","PeriodicalId":36403,"journal":{"name":"中华放射医学与防护杂志","volume":"2009 1","pages":"237-240"},"PeriodicalIF":0.0,"publicationDate":"2020-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86257828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of the effects of immunity index and blood inflammatory markers pre- and post-radiotherapy on prognosis of clinical stage III esophageal cancer patients","authors":"Chunyan Song, Shuchai Zhu, W. Shen, Sina Gao, Xingyu Du, Yan Zhao, Jinrui Xu","doi":"10.3760/CMA.J.ISSN.0254-5098.2020.03.006","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-5098.2020.03.006","url":null,"abstract":"Objective \u0000To study the effects of immunity index and blood inflammatory markers pre- and post-radiotherapy on prognosis of esophageal cancer patients with clinical stage Ⅲ. \u0000 \u0000 \u0000Methods \u0000A total of 84 esophageal cancer patients with clinical stage Ⅲ (T4N1M0) in Fourth Hospital of Hebei Medical University were analyzed, from May 2010 to April 2012. Intensity-modulated radiotherapy was delivered with a dose of 56-66 Gy/1.8-2.0 Gy per fraction. Flow cytometry was used to analyze the distribution of T-lymphocyte subsets (CD3, CD4, CD8, CD4/CD8) and natural killer cells (CD56) in the peripheral blood pre- and post- radiotherapy. Neutrophil-lymphocyte ratio (NLR) pre- and post- radiotherapy were also tested. The correlation of immunity index and blood inflammatory markers with prognosis was analyzed by univariate and multivariate analysis. \u0000 \u0000 \u0000Results \u0000For all patients, the 1-, 3- and 5-year overall survival (OS) rates were 78.57%, 34.52% and 19.59%, respectively. The median OS time was 22.60 months. The 1-, 3- and 5-year progression free survival (PFS) rates were 69.05%, 27.38% and 12.09%, respectively. The median PFS time was 21.20 months. The objective response rate was 61.90%, with 11 patients of complete remission (CR) and 41 patients of partial remission (PR). Univariate analysis revealed that NLR before radiotherapy, T-lymphocyte subsets (CD3, CD4 and CD4/CD8) after radiotherapy were significantly associated with OS and PFS (OS: χ2=7.851, 4.443, 8.381, 5.972, P<0.05, PFS: χ2= 7.475, 6.290, 9.659, 8.738, P<0.05). Multivariate COX regression analysis showed that NLR before radiotherapy, T-lymphocyte subsets (CD4, CD4/CD8) after radiotherapy were independent prognostic factors for OS (χ2=10.464, 4.292, 5.507, P<0.05). The NLR before radiotherapy and CD4/CD8 after radiotherapy were independent prognostic factors for PFS (χ2=10.835, 8.545, P<0.05). \u0000 \u0000 \u0000Conclusions \u0000Radiotherapy may influence the immune function. NLR before radiotherapy and CD4/CD8 after radiotherapy are of great value in predicting the prognosis of esophageal cancer patients. \u0000 \u0000 \u0000Key words: \u0000Immune system; Blood inflammatory markers; Radiotherapy; Esophageal cancer; Prognosis","PeriodicalId":36403,"journal":{"name":"中华放射医学与防护杂志","volume":"76 1","pages":"189-195"},"PeriodicalIF":0.0,"publicationDate":"2020-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90147602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analyzing quality of life and influencing factors in patients with bone metastasis of hepatocellular carcinoma before and after radiotherapy by bone pain scale","authors":"Chong Geng, Su-ping Sun, T. Ye, Hua Hui, Min Wang, Shaodong Tong","doi":"10.3760/CMA.J.ISSN.0254-5098.2020.03.010","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-5098.2020.03.010","url":null,"abstract":"Objective \u0000To study the effect of radiotherapy on the quality of life (QOL) of patients with bone metastasis of hepatocellular carcinoma by analyzing the Function Assessment of Cancer Treatment(FACT), and to analyze the influence of clinical factors on the improvement of the QOL after radiotherapy. \u0000 \u0000 \u0000Methods \u0000The FACT bone pain scale in 43 patients with bone metastasis of hepatocellular carcinoma before and after radiotherapy was retrospectively analyzed. The changes in QOL score before and after radiotherapy were analyzed by T test from five aspects: overall QOL score, general functional status, pain degree, physical function and social psychology. Further analysis was made on the scores of patients whose QOL had not been improved. Chi-square test was used to analyze the correlation between clinical factors and QOL improvement after radiotherapy. \u0000 \u0000 \u0000Results \u0000After radiotherapy, the QOL of patients were improved in all aspects compared with those before radiotherapy, and there were statistical differences (t=7.621, 5.887, 9.407, 7.785, 4.487, P<0.05). In patients whose QOL did not improve after radiotherapy, the scores of overall QOL and psychosocial assessment decreased significantly, and there were significant differences (t=3.381, 4.982, P<0.05). Among the clinical factors, soft tissue mass at bone metastasis site and radiotherapy prescription dose had significant effects on the improvement of patients′ life after radiotherapy (χ2=5.180, 7.457, P<0.05). Whether there were soft tissue masses in bone metastases before radiotherapy, the improvement rates of QOL after radiotherapy were 50.00% and 85% respectively. The improvement rates of QOL after radiotherapy were 44.44% and 84% in patients with prescription dose of <40 Gy and≥40 Gy respectively. Multivariate analysis showed that soft tissue mass at bone metastasis site, the dose of radiotherapy prescription and numeric rating scale (NRS) of pain had more significant effects on QOL (OR=0.296, 0.020, 1.592, P<0.05). \u0000 \u0000 \u0000Conclusions \u0000Radiotherapy at bone metastasis sites can significantly improve the QOL of liver cancer patients with bone metastasis. Psychosocial status can affect the QOL of patients. In the case of soft tissue mass in bone metastasis site, the prescription dose of radiotherapy (≥40 Gy) can better improve the QOL. \u0000 \u0000 \u0000Key words: \u0000Bone Metastasis of Hepatocellular Carcinoma; Radiotherapy; Bone Pain Scale; Quality of Life","PeriodicalId":36403,"journal":{"name":"中华放射医学与防护杂志","volume":"10 1","pages":"216-220"},"PeriodicalIF":0.0,"publicationDate":"2020-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74738740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of cervical anterior flexion in CT examination of neck for preschool children with Dose Right technique","authors":"Bian Chuanzhen, Jian Zhang, Ying Wang","doi":"10.3760/CMA.J.ISSN.0254-5098.2020.03.015","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-5098.2020.03.015","url":null,"abstract":"Objective \u0000To analyze the influence on radiation dose and image quality of children neck CT with anterior flexion of cervical spine using self-made sponge pad with DoseRight technique. \u0000 \u0000 \u0000Methods \u0000A total of 125 children aged 1-5 years who underwent neck CT examination were consecutively collected prospectively. The patients were divided into control group and test group with computer random number method . The control group was supine on the scanning bed and fixed in the CT skull stent. The test group was supine on the scanning bed with a self-made sponge cushion under the neck to extend the head and droop the shoulder. The data was acquired with Philips Brilliance iCT and CTDIVOL was obtained from the dose report. SSDEED and SSDEWD were calculated seperately.The image quality by measuring the noise value and signal-to-noise ratio of the paravertebral muscle area at the middle level of the third cervical vertebra and thyroid area. Subjective evaluation of image quality by 5-point scoring systemwas performed. \u0000 \u0000 \u0000Results \u0000The noise values of paravertebral muscles and thyroid regions in the test group were lower than those in the control group(t=-6.93, -7.41, P<0.05), and the signal-to-noise ratios were higher than those in the control group (t=5.74, 6.14, P<0.05). The subjective score of the test group (4.32±0.70) was better than that of the control group (3.70±0.66), and the difference was statistically significant (Z=-4.27, P<0.05). The jaw-pharynx angle and the number of vertebra displayed of the test group were higher than those of the control group (t=4.94, 5.09, P<0.05). CTDIVOL, and in the control group were 22.1%, 26.0% and 27.1% higher than those in the test group (t=6.17, 5.11, 4.35, P<0.01). \u0000 \u0000 \u0000Conclusions \u0000is more accurate to indicate the CT radiation dose of children. The self-made sponge pad keeping the cervical spine in anterior flexion can reduce radiation dose and improve image quality. \u0000 \u0000 \u0000Key words: \u0000Neck; Preschool children; Radiation dose; Size-specific dose estimate","PeriodicalId":36403,"journal":{"name":"中华放射医学与防护杂志","volume":"134 1","pages":"241-246"},"PeriodicalIF":0.0,"publicationDate":"2020-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77359676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognosis and failure patterns of esophageal squamous cell carcinoma patients undergoing selective lymph node irradiation","authors":"W. Shen, Hong-mei Gao, Jinrui Xu, Shu-guang Li, You-mei Li, Shuchai Zhu","doi":"10.3760/CMA.J.ISSN.0254-5098.2020.03.007","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-5098.2020.03.007","url":null,"abstract":"Objective \u0000To investigate the prognosis and failure mode of patients with esophageal squamous cell carcinoma receiving selective lymph node irradiation (ENI). \u0000 \u0000 \u0000Methods \u0000A total of 179 eligible patients with esophageal squamous cell carcinoma were retrospectively analyzed. The prognostic value of tumor-related factors, the influencing factors of short-term curative effect and prognosis of patients, and the single and multi factor indexes of affecting the overall survival rate (OS), progression free survival rate (PFS) and recurrence of patients were analyzed.SPSS 19.0 software was used for statistical analysis. \u0000 \u0000 \u0000Results \u0000The 1, 3- and 5-year OS of the whole group were 77.1%, 40.1% and 26.0%, respectively, and 1-, 3- and 5-year PFS were 62.6%, 30.6%, and 20.3%, respectively. Multivariate analysis showed that hoarseness, cN stage, cTNM stage, GTV-transverse diameter (GTV-D) and GTV-volume/length (GTV-V/L) were independent factors affecting OS (P<0.05). The sonar, cTNM staging, and short-term efficacy were independent factors affecting PFS (P<0.05). Recurrence occurred in 75 patients (41.9%) in the whole group, and 61 patients (34.1%) had distant metastases. Among them, 9 patients (10.6%) had both recurrence and distant metastasis. Of the 75 patients with recurrence, 64(85.3%) had simple esophageal recurrence, 4(5.3%) had lymph node recurrence, and 7 (9.3%) had both. Recurrence occurred in 18 of the 63 patients who achieved CR after treatment. Only 2 patients had lymph node recurrence. Logistic multivariate analysis showed that the surrounding tissue/organ invasion, GTV-D and short-term were independent factors affecting the recurrence rate (P<0.05). \u0000 \u0000 \u0000Conclusions \u0000ENI is feasible in patients with esophageal squamous cell carcinoma, and the main mode of failure is esophageal recurrence. Pre-treatment sonar, larger GTV-D and GTV-V/L, more advanced clinical stage and poorer short-term efficacy are indicators of poor prognosis, while the peripheral tissue involvement, GTV-D and short-term efficacy are the independent factors that influence failure. \u0000 \u0000 \u0000Key words: \u0000Esophageal neoplasms/esophageal squamous cell carcinoma; Intensity modulated conformal radiotherapy; Elective nodal irradiation; Prognosis; Failure mode","PeriodicalId":36403,"journal":{"name":"中华放射医学与防护杂志","volume":"32 1","pages":"196-202"},"PeriodicalIF":0.0,"publicationDate":"2020-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76016039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dosimetric comparison study and short-term clinical outcomes of proton and carbon ion radiotherapy for thymic malignancies","authors":"Jian Chen, N. Ma, Yan Lu, K. Shahnazi, Jingfang Zhao, J. Lu, G. Jiang, J. Mao","doi":"10.3760/CMA.J.ISSN.0254-5098.2020.03.011","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-5098.2020.03.011","url":null,"abstract":"Objective \u0000To compare dose distributions between photon versus proton and carbon ion radiotherapy (particle therapy, PT) among patients with gross tumors, and to evaluate the safety and efficacy of PT for thymic malignancies (TM). \u0000 \u0000 \u0000Methods \u0000From Sept 2015 to Aug 2018, 19 patients with TM who underwent non-palliative PT using pencil beam scanning technique in our hospital and had at least one follow-up were retrospectively analyzed. Diseases staged from Ⅰ-ⅣB including 15 Ⅲ-ⅣB. All the patients had pathological diagnosis with 10 thymomas, 6 carcinomas and 3 neuroendocrine tumors of the thymus. A set of dosimetric comparisons were conducted in patients with gross tumors at a total dose of 66 GyE, in 33 fractions for photon or proton beams and in 22 fractions for carbon ion beams. Five patients without any local treatment and 7 patients after R2 resection received radical radiotherapy of proton 44.0-48.4 GyE in 20-22 fractions plus carbon ion 21.0-23.1 GyE in 7 fractions, 1 case after complete resection (R0 resection) had proton 45 GyE in 25 fractions, 5 cases after R1 resection had proton 60.0-61.6 GyE in 28-30 fractions and 1 case of recurrence after postoperative radiotherapy had only carbon ion 60 GyE in 20 fractions. \u0000 \u0000 \u0000Results \u0000The median follow up time was 19.0 (2.4-42.9) months. There were 13 patients with gross tumors, with a median largest diameter of 5.7 (2.7-12.8) cm. The dosimetric study showed that proton and carbon-ion plans significantly reduced the maximum dose to the spinal cord, the mean doses to the organs at risk (OARs) including the lung/heart/esophagus, and the integral dose of the exposed area about 25%-65% compared to photon plans. No other toxicities ≥ grade 3 were observed except one myocardial infarction (grade 4 late toxicity). There was no local failure observed. Metastasis to regional lymph node, lung, pleura, skull base, bone or liver occurred in 4 patients with Ⅲ-ⅣB stage disease in 6.1-22.8 months after treatment. The 2-year local control and overall survival rates were 100%, disease free survival and distant metastasis free survival rates were 64.6%. \u0000 \u0000 \u0000Conclusions \u0000For TMs, PT has significant advantages over photon in terms of sparing OARs, and is safe and effective in patients with TMs after short-time follow-up. \u0000 \u0000 \u0000Key words: \u0000Thymic malignancies; Proton; Carbon ion; Radiotherapy; Pencil beam scanning","PeriodicalId":36403,"journal":{"name":"中华放射医学与防护杂志","volume":"1 1","pages":"221-226"},"PeriodicalIF":0.0,"publicationDate":"2020-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89490284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A feasibility study of local adaptation of Lung SBRT RapidPlan commercial model","authors":"Haiyang Wang, Hao Wu, Xiaoyu Xiang, Yuliang Huang, Chenguang Li, Q. Hu, Yixiao Du, Jian Gong, Weibo Li, Yibao Zhang","doi":"10.3760/CMA.J.ISSN.0254-5098.2020.03.008","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-5098.2020.03.008","url":null,"abstract":"Objective \u0000To explore the feasibility and optimization effect of modifying the Henry Ford Hospital (HFHS) RapidPlan model for stereotactic body radiation therapy planning based on local requirements. \u0000 \u0000 \u0000Methods \u0000The following changes were made based on Henry Ford Health System(HFHS) Rapid Plan Lung SBRT model, taking the latest clinical guideline evidence and local clinical practice into account: Internal gross target volume(IGTV) and organ at risk(OAR) structure, lung, were added and set corresponding parameters.The upper value of planning target volume (PTV) was adjusted from 109% to 125%. The original training library was replaced with 73 local historical simultaneous integrated boosting plans, and statistical verification and outlier cleaning of the initial trained model were performed using Model Analytics software. Totally 10 cases not included in the model library were selected for independent verification, and automatic optimization result of the models before and after modifying were compared under the same beam condition. The following dosimetric parameters were compared after target dose normalization: conformal index (CI) of target volume, the mean doses, maximum doses and dose-volume parameters of OARs. \u0000 \u0000 \u0000Results \u0000The \" tail\" of the PTV′s DVH and the \" shoulder\" and \" tail\" of the IGTV′s DVH of model M(local) validation plan (M(local)_P) performs higher than the original model HFHS (HFHS_P). The PTV_CI (1.07±0.13) of Mlocal_P were significantly smaller than HFHS_P (1.25±0.24) (Z=-2.497, P<0.05). Except for Heart_D15 cm3 and Heart_Dmax, most of the Mlocal_P dosimetric parameters of OARs were lower than HFHS_P, and the standard deviation was smaller. However, the difference of between two plans was no more than 3.06%. 10 HFHS_P plans don′t satisfy dose parameters requirement, two of which PTV_CI values are 1.52 and 1.74, far beyond the clinically acceptable range. \u0000 \u0000 \u0000Conclusions \u0000Commercial model HFHS could be localized by replacing training library and adjusting parameters. Moreover, plans optimized by the modified model are local clinical acceptable in the aspects of target volume conformity and hotspots, and have a better performance in terms of OAR sparing and plan consistency. \u0000 \u0000 \u0000Key words: \u0000Radiotherapy planning; RapidPlan; Localize; Lung cancer; Stereotactic body radiation therapy","PeriodicalId":36403,"journal":{"name":"中华放射医学与防护杂志","volume":"23 1","pages":"203-208"},"PeriodicalIF":0.0,"publicationDate":"2020-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87469611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}