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Incidence and management of deep surgical site infection following spinal deformity surgery: 8 818 cases at a single institution 脊柱畸形手术后深部手术部位感染的发生率和处理:8188例单一机构病例
Q4 Medicine Pub Date : 2020-02-16 DOI: 10.3760/CMA.J.ISSN.0253-2352.2020.04.005
Muyi Wang, Bin Wang, Y. Qiu, Ze-zhang Zhu, C. Du, Liang Xu, Qinshuang Zhou, Bo Yang
Objective To investigate the incidence and management of deep surgical site infection(SSI) after the spinal deformity surgery. Methods This study retrospectively reviewed a consecutive cohort of 8818 patients with spinal deformity who received spinal deformity surgery between January1998 and December 2017 at our center. The diagnosis of deep SSI was based on the clinical symptoms, imaging data and laboratory findings. Early infection and late infection were defined as deep infections occurring 3 months after the initial procedure, respectively. All deep SSIs were first treated with irrigation and debridement, closed suction irrigation system and antibiotics. If the infection cannot be eradicated, dressing change is recommended within 2 years after the initial surgery. The instrumentation can be removed 2 years after the initial surgery with careful evaluation of the fusion mass. The posterior-anterior and lateral radiographs were used to measure the coronal parameters and sagittal alignment. Results Sixty patients were diagnosed as deep SSI after spinal deformity surgery, including 11 patients with early infection and 49 patients with late infection. No significant difference was observed in terms of age, gender ratio, surgical approach and fusion levels between the two groups. Deep SSI seemed to be more likely to occur between 2 and 5 years after surgery. Incidence of SSI was lowest in the patients with idiopathic scoliosis and ankylosing spondylitis, and highest in the patients with neuromuscular and syndromic scoliosis. There was a high rate of negative culture in the primary culture. Staphylococcus aureus and Escherichia coli were the most common organisms in the early infection, while patients with late infection had a high rate of low-virulent skin flora. In the early infection group, nine patients retained instrumentation while the implants were removed 2 years after the primary surgery in 2 patients. In patients with late infection, instrumentation was retained in 5 cases and removed in 10 cases until 2 years after the primary surgery. 34 cases were infected 2 years after the primary surgery and the implants were removed directly. One patient underwent reoperation with instrumentation 1 month after implant removal, another patient underwent reoperation 3 years after implant removal due to progression of deformity. Significant loss of coronal correction was noted at the latest follow-up. Conclusion The rate of deep SSI after spinal deformity surgery was 0.68%, of which the incidence of early infection and delayed infection was 0.12% and 0.56%, respectively. An increased risk of SSI in patients with neuromuscular and syndromic scoliosis was noted. If the infection cannot be eradicated after repeated debridement, we recommend instrumentation removal 2 years after the initial surgery, but there is still a high risk of loss of correction in these patients. Key words: Scoliosis; Kyphosis; Spinal fusion; Infection; Treat
目的探讨脊柱畸形术后深部手术部位感染的发生率及处理方法。方法本研究回顾性分析了1998年1月至2017年12月在我中心接受脊柱畸形手术的8818名脊柱畸形患者的连续队列。深部SSI的诊断是基于临床症状、影像学数据和实验室检查结果。早期感染和晚期感染分别定义为初次手术后3个月发生的深度感染。所有深部SSI首先采用冲洗和清创术、封闭抽吸冲洗系统和抗生素进行治疗。如果感染无法根除,建议在初次手术后2年内更换敷料。可以在初次手术后2年内取出器械,仔细评估融合块。使用前后侧位X线片测量冠状面参数和矢状面排列。结果60例脊柱畸形术后诊断为深部SSI,其中早期感染11例,晚期感染49例。在年龄、性别比例、手术方式和融合水平方面,两组之间没有观察到显著差异。深部SSI似乎更有可能发生在手术后2至5年之间。SSI的发生率在特发性脊柱侧弯和强直性脊柱炎患者中最低,在神经肌肉性和综合征性脊柱侧侧凸患者中最高。在原代培养中,阴性培养率较高。金黄色葡萄球菌和大肠杆菌是早期感染最常见的生物体,而晚期感染患者的皮肤低毒力菌群比例较高。在早期感染组中,9名患者保留了器械,2名患者在初次手术后2年移除了植入物。在晚期感染患者中,5例保留了器械,10例移除器械,直到初次手术后2年。34例患者在初次手术后2年被感染,植入物被直接移除。一名患者在植入物移除后1个月接受了器械再次手术,另一名患者因畸形进展在植入物取出后3年接受了再次手术。在最近的随访中注意到冠状位矫正的显著损失。结论脊柱畸形术后深部SSI发生率为0.68%,其中早期感染和延迟感染的发生率分别为0.12%和0.56%。神经肌肉和综合征性脊柱侧弯患者发生SSI的风险增加。如果反复清创术后感染无法根除,我们建议在初次手术后2年取出器械,但这些患者仍有很高的矫正失败风险。关键词:脊柱侧弯;Kyphosis;脊柱融合术;感染;治疗结果
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引用次数: 0
Prediction of mechanical complications after corrective surgeries in adult degenerative scoliosis: modification and validation of the global alignment and proportion (GAP) score 成人退行性脊柱侧弯矫正术后机械并发症的预测:整体排列和比例(GAP)评分的修改和验证
Q4 Medicine Pub Date : 2020-02-16 DOI: 10.3760/CMA.J.ISSN.0253-2352.2020.04.001
H. Ma, B. Shi, Zhen Liu, Ze-zhang Zhu
Objective To modify the global alignment and proportion (GAP) score according to the spinopelvic alignment of healthy volunteers and to validate the reliability of the GAP score and the modified GAP (M-GAP) score in the prediction of mechanical failure after corrective surgeries in adult degenerative scoliosis (ADS). Methods Clinical and radiographical data of 66 ADS patients undergoing correction surgeries in our center between January 2014 and January 2017 were retrospectively reviewed. The average age of the cohort was 60.2±7.1 years, including 13 male patients and 53 female patients. The predictive ability of GAP score to the mechanical failure was validated with Fisher's exact test and Linear-by-linear association test. Sagittal spinopelvic parameters were measured on lateral full-spine X-rays of 67 healthy volunteers aged between 50 and 70. The average age of these subjects was 58.2±5.4 years. Values of spinal and pelvic parameters including pelvic incidence (PI), sacral slope (SS), lumbar lordosis (LL), global tilt (GT) and sagittal vertical axis (SVA) were measured. Simple linear regression analysis was conducted between PI and SS, LL and GT, respectively. The equations of regression analysis were used to calculate patients' ideal SS, LL and GT, and to establish the modified GAP (M-GAP) score. The predictive ability of M-GAP score to the mechanical failure was also validated. Results Sagittal spinal and pelvic parameters of healthy subjects were measured and illustrated. The correlations between SS, LL and PI were SS=0.40×PI+12, LL=0.46×PI+22 and GT=0.46×PI-5. According to the GAP score, the postoperative sagittal spinopelvic alignment was proportioned in 16 (24.2%) cases, moderately disproportioned in 32 (48.5%) cases and severely disproportioned in 18 (27.3%) cases according to the original GAP score, and the occurrence of mechanical complication was 18.8% (3/16), 12.5% (4/32) and 22.2%(4/18) respectively. The GAP categories were not significantly correlated with the prevalence of mechanical failure (P=0.633), and no significant linear correlation was found (χ2=5.022, P=0.822). After re-evaluation of M-GAP score, the postoperative sagittal spinopelvic alignment was proportioned in 32 (48.5%) cases, moderately disproportioned in 25 (37.9%) cases and severely disproportioned in 9 (13.6%) cases, and the occurrence of mechanical failure was 6.3% (2/32), 24.0% (6/25) and 30%(3/9), respectively. The prevalence of mechanical failure was statistically different between proportioned, moderately disproportioned and severely disproportioned spinopelvic alignment patients classified by M-GAP score (P=0.048), and there was a statistically significant linear association between the M-GAP categories and the occurrence of mechanical complications (χ2=0.093, P=0.034). Conclusion Poor predictive ability of the original GAP score to the mechanical failure was detected in ADS patients. However, the modified GAP score seemed to be a relia
目的根据健康志愿者的脊柱骨盆排列,修改整体排列和比例(GAP)评分,验证GAP评分和改良GAP评分在预测成人退行性脊柱侧凸(ADS)矫正术后机械故障中的可靠性。方法回顾性分析2014年1月至2017年1月在我中心接受矫正手术的66例ADS患者的临床和放射学资料。队列的平均年龄为60.2±7.1岁,包括13名男性患者和53名女性患者。采用Fisher精确检验和线性关联检验验证GAP评分对机械失效的预测能力。在67名年龄在50岁至70岁之间的健康志愿者的横向全脊柱X光片上测量了矢状棘盆腔参数。这些受试者的平均年龄为58.2±5.4岁。测量脊柱和骨盆参数的值,包括骨盆发生率(PI)、骶骨斜率(SS)、腰椎前凸(LL)、整体倾斜(GT)和矢状垂直轴(SVA)。分别对PI和SS、LL和GT进行简单线性回归分析。采用回归分析方程计算患者的理想SS、LL和GT,并建立修正的GAP(M-GAP)评分。M-GAP评分对机械失效的预测能力也得到了验证。结果对健康受试者的矢状位脊柱和骨盆参数进行了测量和说明。SS、LL和PI的相关性分别为:SS=0.40×PI+12、LL=0.46×PI+22和GT=0.46×PI-5。根据GAP评分,术后脊柱-骨盆矢状位排列与原始GAP评分成比例的有16例(24.2%),中等比例的有32例(48.5%),严重比例的有18例(27.3%),机械并发症的发生率分别为18.8%(3/16),12.5%(4/32)和22.2%(4/18)。GAP分类与机械故障的发生率无显著相关性(P=0.633),也无显著线性相关性(χ2=5.022,P=0.822)。重新评估M-GAP评分后,术后脊柱-骨盆矢状位排列比例为32例(48.5%),中等比例为25例(37.9%),严重比例为9例(13.6%),机械故障发生率分别为6.3%(2/32)、24.0%(6/25)和30%(3/9)。按M-GAP评分分类的比例失调、中度失调和严重失调的脊柱-骨盆排列患者的机械故障发生率有统计学差异(P=0.048),M-GAP评分与机械并发症的发生呈显著的线性相关(χ2=0.093,P=0.034)。然而,改良GAP评分似乎是ADS患者机械衰竭的可靠预测指标。关键词:成人;腰椎;椎间盘退变;脊柱侧弯;术后并发症
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引用次数: 0
The natural history of radiological presentations in Chiari malformation type I with scoliosis: a cross-sectional study Chiari畸形I型伴脊柱侧弯的放射学表现的自然史:一项横断面研究
Q4 Medicine Pub Date : 2020-02-16 DOI: 10.3760/CMA.J.ISSN.0253-2352.2020.04.002
Zhong He, X. Qin, Rui Yin, Y. Qiu
Objective To investigate the radiological presentations in relation to different ages in scoliosis associated with Chiari malformation typeⅠ(CMI). Methods A retrospective analysis was performed on 80 patients diagnosed with scoliosis associated with CMI from June 2010 to June 2018, who were classified into three groups according to their age: Children(age≤10 years), Adolescents (age 11-18 years) and Adults (age≥19 years). Curves were classified into typical and atypical patterns in the coronal plane. The coronal and sagittal radiographical parameters were measured in the three groups. Moreover, cerebellar tonsillar descent and syringomyelia patterns were measured on MRI, and the parameters among the three groups were compared statistically. Results The incidence of atypical curve patterns in Children (10 patients), Adolescents (44 patients) and Adults (26 patients) was 30.0%, 15.9%, and 50.0%, respectively (χ2=2.654, P=0.265). There was no statistical difference in the distribution of curve patterns among CMI patients with different age. In the coronal profile, Cobb angle (F=16.751, P<0.001) and flexibility (F=3.285, P=0.044) of main curve, Cobb angle of secondary curve (F=9.805, P<0.001) and coronal balance(CB) (F=5.249, P=0.007) showed statistical difference. The elderly patients tended to have larger Cobb angle of main and secondary curve with worse flexibility of main curve, and CB in Adolescents was better than the other two groups. In the sagittal profile, TK (F=4.324, P=0.017), LL (F=4.590, P=0.013), PI (F=5.501, P=0.006), and PT (F=3.220, P=0.045) showed statistical difference in the three groups, which were increasing significantly with aging. MRI parameters showed that younger patients were more likely to have a higher degree of cerebellar tonsillar descent (χ2=18.479, P<0.001) and distended syringomyelia (χ2=23.074, P=0.003). Conclusion With aging, Cobb angle of main curve is progressive, and the flexibility is worse, suggesting that early surgical intervention should be performed to reduce the risk of surgery. In addition, cerebellar tonsillar descent and syringomyelia in elderly patients are milder than young patients, indicating that there might be spontaneous remission. Key words: Arnold-Chiari malformation; Scoliosis; Syringomyelia; Age factors; Cross-sectional studies
目的探讨不同年龄段脊柱侧弯合并Chiari畸形Ⅰ型(CMI)的影像学表现。方法对2010年6月至2018年6月诊断为脊柱侧弯合并CMI的80例患者进行回顾性分析,根据年龄分为三组:儿童(年龄≤10岁)、青少年(年龄11-18岁)和成人(年龄≥19岁)。冠状面上的曲线分为典型和非典型两种。测量了三组患者的冠状面和矢状面放射学参数。此外,在MRI上测量小脑扁桃体下降和脊髓空洞症模式,并对三组之间的参数进行统计学比较。结果儿童(10例)、青少年(44例)和成人(26例)不典型曲线型的发生率分别为30.0%、15.9%和50.0%(χ2=2.654,P=0.0265),不同年龄CMI患者的曲线型分布无统计学差异。冠状剖面中,主曲线的Cobb角(F=16.751,P<0.001)和柔韧性(F=3.285,P=0.044)、次曲线的Cobbl角(F=9.805,P<0.001。老年患者的主、副曲线Cobb角较大,主曲线柔韧性较差,青少年CB优于其他两组。在矢状面上,TK(F=4.324,P=0.017)、LL(F=4.590,P=0.013)、PI(F=5.501,P=0.006)和PT(F=3.20,P=0.045)在三组中显示出统计学差异,这些差异随着年龄的增长而显著增加。MRI参数显示,年龄较小的患者更有可能出现更高程度的小脑扁桃体下降(χ2=18.479,P<0.001)和扩张性脊髓空洞症(χ2=23.074,P=0.003)。此外,老年患者的小脑扁桃体下降和脊髓空洞症比年轻患者轻,表明可能有自发缓解。关键词:Arnold-Chiari畸形;脊柱侧弯;脊髓空洞症;年龄因素;横断面研究
{"title":"The natural history of radiological presentations in Chiari malformation type I with scoliosis: a cross-sectional study","authors":"Zhong He, X. Qin, Rui Yin, Y. Qiu","doi":"10.3760/CMA.J.ISSN.0253-2352.2020.04.002","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0253-2352.2020.04.002","url":null,"abstract":"Objective \u0000To investigate the radiological presentations in relation to different ages in scoliosis associated with Chiari malformation typeⅠ(CMI). \u0000 \u0000 \u0000Methods \u0000A retrospective analysis was performed on 80 patients diagnosed with scoliosis associated with CMI from June 2010 to June 2018, who were classified into three groups according to their age: Children(age≤10 years), Adolescents (age 11-18 years) and Adults (age≥19 years). Curves were classified into typical and atypical patterns in the coronal plane. The coronal and sagittal radiographical parameters were measured in the three groups. Moreover, cerebellar tonsillar descent and syringomyelia patterns were measured on MRI, and the parameters among the three groups were compared statistically. \u0000 \u0000 \u0000Results \u0000The incidence of atypical curve patterns in Children (10 patients), Adolescents (44 patients) and Adults (26 patients) was 30.0%, 15.9%, and 50.0%, respectively (χ2=2.654, P=0.265). There was no statistical difference in the distribution of curve patterns among CMI patients with different age. In the coronal profile, Cobb angle (F=16.751, P<0.001) and flexibility (F=3.285, P=0.044) of main curve, Cobb angle of secondary curve (F=9.805, P<0.001) and coronal balance(CB) (F=5.249, P=0.007) showed statistical difference. The elderly patients tended to have larger Cobb angle of main and secondary curve with worse flexibility of main curve, and CB in Adolescents was better than the other two groups. In the sagittal profile, TK (F=4.324, P=0.017), LL (F=4.590, P=0.013), PI (F=5.501, P=0.006), and PT (F=3.220, P=0.045) showed statistical difference in the three groups, which were increasing significantly with aging. MRI parameters showed that younger patients were more likely to have a higher degree of cerebellar tonsillar descent (χ2=18.479, P<0.001) and distended syringomyelia (χ2=23.074, P=0.003). \u0000 \u0000 \u0000Conclusion \u0000With aging, Cobb angle of main curve is progressive, and the flexibility is worse, suggesting that early surgical intervention should be performed to reduce the risk of surgery. In addition, cerebellar tonsillar descent and syringomyelia in elderly patients are milder than young patients, indicating that there might be spontaneous remission. \u0000 \u0000 \u0000Key words: \u0000Arnold-Chiari malformation; Scoliosis; Syringomyelia; Age factors; Cross-sectional studies","PeriodicalId":36405,"journal":{"name":"中华骨科杂志","volume":"40 1","pages":"199-207"},"PeriodicalIF":0.0,"publicationDate":"2020-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48600901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The long-term results of growth friendly non-fusion technique in the treatment of early-onset scoliosis 生长友好型非融合技术治疗早发性脊柱侧凸的远期效果
Q4 Medicine Pub Date : 2020-02-16 DOI: 10.3760/CMA.J.ISSN.0253-2352.2020.04.004
Liang Xu, Xu Sun, Bo Yang, C. Du, Qingshuang Zhou, Muyi Wang, Bin Wang, Yang Yu, B. Qian, Ze-zhang Zhu
Objective To evaluate long-term results of growth friendly non-fusion technique (GF) in the treatment of early-onset scoliosis (EOS). Methods From August 2008 to October 2019, a total of 26 EOS patients (mean age 7.2±2.4 years old) who had completed surgery with GF treatment, including 12 males and 14 females, were reviewed retrospectively. Among them, 16 patients underwent growing rod treatment while 10 patients underwent vertical expandable prosthetic titanium rib (VEPTR) treatment. All patients had minimum 2 lengthening procedure during distraction period and over 2-year follow-up after graduation. Radiographic data were collected before and after index surgery as well as at graduation and the latest follow-up. Complications were also recorded during distraction period and after graduation. Results A total of 145 lengthening procedures were performed in 26 patients, averagely 5.6 procedures per patient. The mean age at graduation was 12.6±1.6 years old. The average follow-up was 4.7±1.4 years duringdistraction period, and 2.9±0.9 years after graduation.The main Cobb angle was significantly decreased from 81.2°±17.3° to 41.1°±13.1°(t=8.124, P<0.001)after the index surgery, but slightly increased to 48.8°±15.4° at the end of distraction. After definitive spinal fusion, the main Cobb angle was notably decreased from 52.8°±16.1° to 45.4°±14.8° in 16 patients(t=2.415, P=0.035), with an average correction rate of 14.1%±9.4%. At the latest follow-up, the main Cobb angle was 45.2°±15.6° and the average correction rate was 44.3%±15.5% when comparing with the value before the index surgery. The thoracic and spinal height were significantly increased after initial surgery. During distraction period, the average gain of thoracic and spinal height was 3.3±0.9 cm and 5.6±1.9 cm, with the growth rate of 0.6±0.3 cm and 1.0±0.4 cm per distraction, respectively. A total of 36complications were recorded in 14 patients. There were 27 complications occurred during distraction period and 9 after graduation. Conclusion Surgical management of EOS with growing rod and VEPTR could effectively correct the spinal deformity and maintain spinal growth. The complication rate after graduation was relative lower than distraction period. However, the correction of definitive spinal fusion during graduation was relative lower. Key words: Child; Scoliosis; Orthopedic fixation devices; Follow-up studies; Spinal fusion
目的评价生长友好型非融合技术(GF)治疗早发型脊柱侧凸(EOS)的远期疗效。方法回顾性分析2008年8月至2019年10月26例完成GF治疗手术的EOS患者(平均年龄7.2±2.4岁),其中男性12例,女性14例。其中16例采用生长棒治疗,10例采用垂直可膨胀假体钛肋骨(VEPTR)治疗。所有患者在牵引期间至少进行了2次延长手术,毕业后随访2年以上。收集指数手术前后、毕业及最近一次随访时的影像学资料。同时记录牵张期间及毕业后的并发症。结果26例患者共行145例延长手术,平均5.6例。平均毕业年龄为12.6±1.6岁。离校期间平均随访4.7±1.4年,毕业后平均随访2.9±0.9年。主Cobb角由指数术后的81.2°±17.3°显著降低至41.1°±13.1°(t=8.124, P<0.001),牵张结束时略有升高至48.8°±15.4°。16例患者经脊柱融合术后,主Cobb角由52.8°±16.1°显著降低至45.4°±14.8°(t=2.415, P=0.035),平均矫正率为14.1%±9.4%。最新随访时,与指数术前比较,主Cobb角为45.2°±15.6°,平均矫正率为44.3%±15.5%。术后胸椎高度和脊柱高度均明显增高。牵张期间胸椎和脊柱的平均高度分别增加3.3±0.9 cm和5.6±1.9 cm,每次牵张分别增加0.6±0.3 cm和1.0±0.4 cm。14例患者共发生36例并发症。牵张期并发症27例,毕业后并发症9例。结论采用生长棒和VEPTR对EOS进行手术治疗,可有效矫正脊柱畸形,维持脊柱生长。毕业后并发症发生率相对低于牵引期。然而,毕业期脊柱融合的矫正率相对较低。关键词:儿童;脊柱侧弯;骨科固定器械;后续研究;脊柱融合术
{"title":"The long-term results of growth friendly non-fusion technique in the treatment of early-onset scoliosis","authors":"Liang Xu, Xu Sun, Bo Yang, C. Du, Qingshuang Zhou, Muyi Wang, Bin Wang, Yang Yu, B. Qian, Ze-zhang Zhu","doi":"10.3760/CMA.J.ISSN.0253-2352.2020.04.004","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0253-2352.2020.04.004","url":null,"abstract":"Objective \u0000To evaluate long-term results of growth friendly non-fusion technique (GF) in the treatment of early-onset scoliosis (EOS). \u0000 \u0000 \u0000Methods \u0000From August 2008 to October 2019, a total of 26 EOS patients (mean age 7.2±2.4 years old) who had completed surgery with GF treatment, including 12 males and 14 females, were reviewed retrospectively. Among them, 16 patients underwent growing rod treatment while 10 patients underwent vertical expandable prosthetic titanium rib (VEPTR) treatment. All patients had minimum 2 lengthening procedure during distraction period and over 2-year follow-up after graduation. Radiographic data were collected before and after index surgery as well as at graduation and the latest follow-up. Complications were also recorded during distraction period and after graduation. \u0000 \u0000 \u0000Results \u0000A total of 145 lengthening procedures were performed in 26 patients, averagely 5.6 procedures per patient. The mean age at graduation was 12.6±1.6 years old. The average follow-up was 4.7±1.4 years duringdistraction period, and 2.9±0.9 years after graduation.The main Cobb angle was significantly decreased from 81.2°±17.3° to 41.1°±13.1°(t=8.124, P<0.001)after the index surgery, but slightly increased to 48.8°±15.4° at the end of distraction. After definitive spinal fusion, the main Cobb angle was notably decreased from 52.8°±16.1° to 45.4°±14.8° in 16 patients(t=2.415, P=0.035), with an average correction rate of 14.1%±9.4%. At the latest follow-up, the main Cobb angle was 45.2°±15.6° and the average correction rate was 44.3%±15.5% when comparing with the value before the index surgery. The thoracic and spinal height were significantly increased after initial surgery. During distraction period, the average gain of thoracic and spinal height was 3.3±0.9 cm and 5.6±1.9 cm, with the growth rate of 0.6±0.3 cm and 1.0±0.4 cm per distraction, respectively. A total of 36complications were recorded in 14 patients. There were 27 complications occurred during distraction period and 9 after graduation. \u0000 \u0000 \u0000Conclusion \u0000Surgical management of EOS with growing rod and VEPTR could effectively correct the spinal deformity and maintain spinal growth. The complication rate after graduation was relative lower than distraction period. However, the correction of definitive spinal fusion during graduation was relative lower. \u0000 \u0000 \u0000Key words: \u0000Child; Scoliosis; Orthopedic fixation devices; Follow-up studies; Spinal fusion","PeriodicalId":36405,"journal":{"name":"中华骨科杂志","volume":"40 1","pages":"217-225"},"PeriodicalIF":0.0,"publicationDate":"2020-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46528504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of biomechanical properties of cervical paravertebral foramen screws, lateral mass screws and pedicle screws 颈椎椎旁孔螺钉、侧块螺钉和椎弓根螺钉生物力学性能比较
Q4 Medicine Pub Date : 2020-02-16 DOI: 10.3760/CMA.J.ISSN.0253-2352.2020.04.006
Xi Chen, Xinyu Liu, Qing Yang, Yifan Liu, Suomao Yuan
Objective To investigate and compare the biomechanical strength of paravertebral foramen screws (PVFS), lateral mass screws (LMS) and pedicle screws (PS). Methods A total of 30 human cervical spine vertebrae (C3-C6) were harvested from 8 fresh-frozen cadaver specimens whose mean age was 45.3±11.2 years at death. The vertebrae were randomly divided into three groups for specific screws. For each vertebra, one side was randomly chosen for direct pullout strength test (speed 5 mm/s), and the other side for fatigue test (displacement ±1.0 mm, frequency 1 Hz, 500 cycles) and residual pullout strength test. 4.5 mm × 12 mm screws were used for PVFS, 3.5 mm × 14 mm screws for LMS, and 3.5 mm × 24 mm screws for PS. Results The direct pullout strength was 327.10±17.07 N for PVFS, 305.71 ± 11.63 N for LMS, and 635.67 ± 22.82 N for PS. The residual pullout strength was 265.62 ±18.19 N for PVFS, 192.80 ±17.10 N for LMS, and 494.89 ±41.79 N for PS. The residual pullout strength of PVFS, LMS and PS respectively, compared with the direct pullout strength, decreased by 18.8%, 36.93% and 22.15% (tPVFS=7.795, tLMS=17.267, tPS=9.349, P<0.001). The direct pullout strength of PS was higher than that of PVFS and LMS(t=34.245, t=40.741, P< 0.001), as well as PVFS was slightly higher than LMS (t=3.275, P=0.004). The residual pullout strength of PS was the highest, PVFS was the second, and LMS was the smallest (F=314.619, P<0.001). For the fatigue test, the load at the first cycle and the first time when the set position was reached of PVFS were higher than those of LMS (t=3.625, P=0.002; t=5.388, P<0.001) and PS (t=2.575, P=0.019; t=2.680, P=0.015), but there was no difference between those of LMS and PS (t=0.609, P=0.550; t=1.953, P=0.067). The load at the last cycle of PVFS and PS was higher than that of LMS (t=5.341, P<0.001; t=3.439, P=0.003), while there was no difference between PVFS and PS (t=1.606, P=0.126). Conclusion The direct pullout strength of PVFS was slightly higher than that of LMS, and the residual pullout strength was significantly higher than LMS. The property of fatigue resistance of PVFS was similar to PS and obviously better than LMS. In summary, PVFS can be used as an effective substitute for LMS and PS. Key words: Cervical vertebrae; Spinal fusion; Bone screws; Biomechanics
目的比较椎旁孔螺钉(PVFS)、侧块螺钉(LMS)和椎弓根螺钉(PS)的生物力学强度。方法从8具死亡时平均年龄为45.3±11.2岁的新鲜冷冻尸体标本中采集30块人颈椎(C3-C6)。脊椎被随机分为三组,用于特定的螺钉。对于每个椎骨,随机选择一侧进行直接拉拔强度试验(速度5mm/s),另一侧进行疲劳试验(位移±1.0mm,频率1Hz,500个循环)和残余拉拔强度试验。结果PVFS的直接拔出强度为327.10±17.07N,LMS为305.71±11.63N,PS为635.67±22.82N。PVFS的残余拔出强度分别为265.62±18.19N、192.80±17.10N和494.89±41.79N,LMS和PS的直接拉拔强度分别比直接拉拔强度下降18.8%、36.93%和22.15%(tPVFS=7.795,tLS=17.267,tPS=9.349,P<0.001),在疲劳试验中,PVFS的第一个循环和第一次到达设定位置时的载荷高于LMS(t=3.625,P=0.002;t=5.388,P<0.001)和PS(t=2.575,P=0.019;t=2.680,P=0.015),但LMS和PS之间没有差异(t=0.609,P=0.550;t=1.953,P=0.067)。PVFS和PS在最后一个周期的载荷高于LMS(t=5.341,P<0.001;t=3.439,P=0.003),而PVFS和PS之间没有差别(t=1.606,P=0.126)。结论PVFS的直接拔出强度略高于LMS,并且残余拔出强度显著高于LMS。PVFS的抗疲劳性能与PS相近,明显优于LMS。总之,PVFS可以作为LMS和PS的有效替代品。关键词:颈椎;脊柱融合术;骨螺钉;生物力学
{"title":"Comparison of biomechanical properties of cervical paravertebral foramen screws, lateral mass screws and pedicle screws","authors":"Xi Chen, Xinyu Liu, Qing Yang, Yifan Liu, Suomao Yuan","doi":"10.3760/CMA.J.ISSN.0253-2352.2020.04.006","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0253-2352.2020.04.006","url":null,"abstract":"Objective \u0000To investigate and compare the biomechanical strength of paravertebral foramen screws (PVFS), lateral mass screws (LMS) and pedicle screws (PS). \u0000 \u0000 \u0000Methods \u0000A total of 30 human cervical spine vertebrae (C3-C6) were harvested from 8 fresh-frozen cadaver specimens whose mean age was 45.3±11.2 years at death. The vertebrae were randomly divided into three groups for specific screws. For each vertebra, one side was randomly chosen for direct pullout strength test (speed 5 mm/s), and the other side for fatigue test (displacement ±1.0 mm, frequency 1 Hz, 500 cycles) and residual pullout strength test. 4.5 mm × 12 mm screws were used for PVFS, 3.5 mm × 14 mm screws for LMS, and 3.5 mm × 24 mm screws for PS. \u0000 \u0000 \u0000Results \u0000The direct pullout strength was 327.10±17.07 N for PVFS, 305.71 ± 11.63 N for LMS, and 635.67 ± 22.82 N for PS. The residual pullout strength was 265.62 ±18.19 N for PVFS, 192.80 ±17.10 N for LMS, and 494.89 ±41.79 N for PS. The residual pullout strength of PVFS, LMS and PS respectively, compared with the direct pullout strength, decreased by 18.8%, 36.93% and 22.15% (tPVFS=7.795, tLMS=17.267, tPS=9.349, P<0.001). The direct pullout strength of PS was higher than that of PVFS and LMS(t=34.245, t=40.741, P< 0.001), as well as PVFS was slightly higher than LMS (t=3.275, P=0.004). The residual pullout strength of PS was the highest, PVFS was the second, and LMS was the smallest (F=314.619, P<0.001). For the fatigue test, the load at the first cycle and the first time when the set position was reached of PVFS were higher than those of LMS (t=3.625, P=0.002; t=5.388, P<0.001) and PS (t=2.575, P=0.019; t=2.680, P=0.015), but there was no difference between those of LMS and PS (t=0.609, P=0.550; t=1.953, P=0.067). The load at the last cycle of PVFS and PS was higher than that of LMS (t=5.341, P<0.001; t=3.439, P=0.003), while there was no difference between PVFS and PS (t=1.606, P=0.126). \u0000 \u0000 \u0000Conclusion \u0000The direct pullout strength of PVFS was slightly higher than that of LMS, and the residual pullout strength was significantly higher than LMS. The property of fatigue resistance of PVFS was similar to PS and obviously better than LMS. In summary, PVFS can be used as an effective substitute for LMS and PS. \u0000 \u0000 \u0000Key words: \u0000Cervical vertebrae; Spinal fusion; Bone screws; Biomechanics","PeriodicalId":36405,"journal":{"name":"中华骨科杂志","volume":"40 1","pages":"236-243"},"PeriodicalIF":0.0,"publicationDate":"2020-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47971155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimization system of mesenchymal stem cells for tissue engineering chondrogenic differentiation 间充质干细胞向组织工程软骨分化的优化体系
Q4 Medicine Pub Date : 2020-02-16 DOI: 10.3760/CMA.J.ISSN.0253-2352.2020.04.007
Pan Wu, Zhuo Pei, W. Zeng
Articular cartilage defect is a common joint damage, however, due to the particularity of cartilage tissue, its repair ability is limited. Thus, articular cartilage damage often changes to more severe osteoarthritis which brings huge pain and economic burden to patients. The development of cartilage tissue engineering brings good news to these patients, but also faces great challenges. Because of the characteristics of mesenchymal stem cells(MSCs) including autologous source, amplification and cartilage differentiation potential, MSCs are often used as the seed cells of cartilage tissue engineering and got widely attention. In the commonly used treatment strategy of articular cartilage differentiated from mesenchymal cells, in vitro pre culture and differentiation showed good therapeutic effects.The mesenchymal stem cells collected from the patient were concentrated, cultured and induced differentiation in vitro, a certain number of differentiated chondrocytes were obtained, and then the cells and culture matrix were transplanted to the patient together. However, the tissue engineering cartilage obtained from mesenchymal stem cells cannot fully meet the requirements of clinical treatment. Moreover, due to the differences of disease type, degree and individuality, there are various optimized factors for the treatment of MSCs derived tissue-engineered cartilage transplantation. For the same type of disease treatment, the optimization system still has no unified recognized standard. In order to obtain better adapt to the human body and meet the clinical requirements of articular cartilage, this review focus onoptimized factors of MSCs in the treatment of orthopedic diseases, summarize and analysis the research status, and discuss the induced factorsfrom three aspects: environmental factors, scaffold selection and seed cells.It provides an idea for using mesenchymal stem cells to obtain better tissue-engineered cartilage and to establish a better optimization system.
关节软骨缺损是一种常见的关节损伤,但由于软骨组织的特殊性,其修复能力有限。因此,关节软骨损伤往往演变为更严重的骨关节炎,给患者带来巨大的疼痛和经济负担。软骨组织工程的发展给这些患者带来了好消息,但也面临着巨大的挑战。由于间充质干细胞(MSCs)具有自体来源、扩增和软骨分化潜能等特点,常被用作软骨组织工程的种子细胞而受到广泛关注。在关节软骨间充质细胞分化的常用治疗策略中,体外预培养和分化均表现出良好的治疗效果。收集患者的间充质干细胞,在体外浓缩培养诱导分化,获得一定数量的分化软骨细胞,然后将细胞与培养基质一起移植到患者体内。然而,间充质干细胞获得的组织工程软骨还不能完全满足临床治疗的需要。此外,由于疾病类型、程度和个性的差异,MSCs来源的组织工程软骨移植治疗存在多种优化因素。对于同类型疾病的治疗,优化系统仍没有统一的公认标准。为了获得更好地适应人体和满足临床要求的关节软骨,本文重点对MSCs在骨科疾病治疗中的优化因素进行综述和分析,并从环境因素、支架选择和种子细胞三个方面对诱导因素进行探讨。这为利用间充质干细胞获得更好的组织工程软骨和建立更好的优化体系提供了思路。
{"title":"Optimization system of mesenchymal stem cells for tissue engineering chondrogenic differentiation","authors":"Pan Wu, Zhuo Pei, W. Zeng","doi":"10.3760/CMA.J.ISSN.0253-2352.2020.04.007","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0253-2352.2020.04.007","url":null,"abstract":"Articular cartilage defect is a common joint damage, however, due to the particularity of cartilage tissue, its repair ability is limited. Thus, articular cartilage damage often changes to more severe osteoarthritis which brings huge pain and economic burden to patients. The development of cartilage tissue engineering brings good news to these patients, but also faces great challenges. Because of the characteristics of mesenchymal stem cells(MSCs) including autologous source, amplification and cartilage differentiation potential, MSCs are often used as the seed cells of cartilage tissue engineering and got widely attention. In the commonly used treatment strategy of articular cartilage differentiated from mesenchymal cells, in vitro pre culture and differentiation showed good therapeutic effects.The mesenchymal stem cells collected from the patient were concentrated, cultured and induced differentiation in vitro, a certain number of differentiated chondrocytes were obtained, and then the cells and culture matrix were transplanted to the patient together. However, the tissue engineering cartilage obtained from mesenchymal stem cells cannot fully meet the requirements of clinical treatment. Moreover, due to the differences of disease type, degree and individuality, there are various optimized factors for the treatment of MSCs derived tissue-engineered cartilage transplantation. For the same type of disease treatment, the optimization system still has no unified recognized standard. In order to obtain better adapt to the human body and meet the clinical requirements of articular cartilage, this review focus onoptimized factors of MSCs in the treatment of orthopedic diseases, summarize and analysis the research status, and discuss the induced factorsfrom three aspects: environmental factors, scaffold selection and seed cells.It provides an idea for using mesenchymal stem cells to obtain better tissue-engineered cartilage and to establish a better optimization system.","PeriodicalId":36405,"journal":{"name":"中华骨科杂志","volume":"40 1","pages":"244-256"},"PeriodicalIF":0.0,"publicationDate":"2020-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46195042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application of 3D printed porous artificial vertebra in reconstruction of thoracolumbar tumor 3D打印多孔人工椎体在胸腰椎肿瘤重建中的应用
Q4 Medicine Pub Date : 2020-02-16 DOI: 10.3760/CMA.J.ISSN.0253-2352.2020.04.003
J. Ji, Yong‐cheng Hu
Objective To evaluate the clinical effectiveness of the reconstruction of the thoracic and lumbar spine using the 3D-printed vertebral body after total en bloc spondylectomy. Methods From December 2016 to September 2019, 33 patients with spinal tumors were treated with total en bloc spondylectomy, including 25 males and 8 females with an average age of 58.0 years(range, 15 to 76). The locations of the lesions contained: 29 in the thoracic and 4 in the lumbar. The surgical segments includeda single vertebra in 30 cases, 2 vertebrae in 2 cases, and 3 vertebrae in 1 case. The tumor type: the primary malignant tumor in 6 cases, the metastatic tumor in 27 cases. The preoperative Tomita score was 2-5 points (mean 3.9 points), while Tokuhashi score was 9-15 points (average 11.1 points). Divided into two groups according to different reconstruction methods during total spinal resection, 33 patients with thoracolumbar vertebral body malignant tumors were divided into 3D printed artificial vertebral body reconstruction group (21 patients, 3D printed artificial vertebral body was used for anterior column reconstruction) and titanium Mesh reconstruction group (12 cases, titanium mesh implanted with allograft bone was used for reconstruction). The main observation indicators included the degree of spinal nerve damage and pain recovery, the local tumor control rate, and the incidence of prosthesis sinking. The visual analogue scale (VAS) at 24 hours and 3 months after operation was compared with that before operation using paired design t test. Results All cases were followed up for 3 to 31 months. There was no statistically significant difference in intraoperative blood loss (t=2.042, P>0.05), surgical time (t=0.591, P>0.05), and postoperative drainage (t=0.118, P>0.05) between the two groups. The visual analogue scale (VAS) between the two groups at preoperative, 24 hours and 3 months after operation was not statistically different (P<0.05). The Frankel grading of 31 patients (97.0%) had at least one grade improvement 3 months after operation. During the follow-up period, 12 patients (41.7%) who underwent reconstruction with titanium mesh showed different degrees of subsidence in imaging, and 21 patients who used 3D printed artificial vertebral reconstruction did not exhibit prosthetic deposition. Chi-square test results of postoperative sink rate of the two methods was statistically different (χ2=10.313, P=0.013). Conclusion This preliminary report suggests the 3D-printed vertebral body has good biocompatibility and mechanical stability, which can be used for reconstruction after total en bloc spondylectomy. Key words: Spinal neoplasms; Spinal fusion; Prostheses and implants
目的评价全椎体切除后应用3d打印椎体重建胸腰椎的临床效果。方法2016年12月至2019年9月对33例脊柱肿瘤患者行全椎体切除术,其中男性25例,女性8例,平均年龄58.0岁,年龄范围15 ~ 76岁。病变部位包括:胸部29例,腰椎4例。手术节段为单节30例,2节2例,3节1例。肿瘤类型:原发恶性肿瘤6例,转移性肿瘤27例。术前Tomita评分为2-5分(平均3.9分),Tokuhashi评分为9-15分(平均11.1分)。将33例胸腰椎恶性肿瘤患者根据全脊柱切除时重建方式的不同分为两组,分别分为3D打印人工椎体重建组(21例,采用3D打印人工椎体进行前柱重建)和钛网重建组(12例,采用同种异体骨植入钛网进行重建)。主要观察指标为脊髓神经损伤程度及疼痛恢复程度、局部肿瘤控制率、假体下沉发生率。采用配对设计t检验比较术后24小时和3个月视觉模拟评分(VAS)与术前比较。结果所有病例均随访3 ~ 31个月。两组术中出血量(t=2.042, P>0.05)、手术时间(t=0.591, P>0.05)、术后引流量(t=0.118, P>0.05)比较,差异均无统计学意义。两组患者术前、术后24小时、术后3个月的视觉模拟评分(VAS)比较,差异无统计学意义(P<0.05)。31例(97.0%)患者术后3个月的Frankel评分至少有1级改善。随访期间,12例(41.7%)采用钛网重建的患者影像学表现出不同程度的下沉,21例采用3D打印人工椎体重建的患者未出现假体沉积。两种方法术后沉淀率的卡方检验结果差异有统计学意义(χ2=10.313, P=0.013)。结论本初步报告提示3d打印椎体具有良好的生物相容性和力学稳定性,可用于全椎体切除术后的重建。关键词:脊柱肿瘤;脊柱融合术;假体及植入物
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引用次数: 0
CT anatomical features of the distal humerus in healthy adults 健康成人肱骨远端CT解剖特征
Q4 Medicine Pub Date : 2020-02-01 DOI: 10.3760/CMA.J.ISSN.0253-2352.2020.03.005
Wenbo Yang, Zhe Wang, Qing Han, Zedi Yang, Youqiong Li, Qingsan Zhu, K. Cheng
Objective To study the anatomical features of the distal humerus in Chinese healthy adults. Methods A total of 121 cases of normal elbow joint CT images were selected from the picture archiving and communication system (PACS), and reconstructed and measured on the AW4.5 workstation. Coronal plane and horizontal plane were determined by flexion-extension (FE) axis and humeral shaft, while the sagittal plane was perpendicular to the FE axis. The angle between the axis of humerus medullary cavity and the FE axis of elbow (H-FE angle) was measured on the coronal plane. The capitellar height (CH), lateral trochlear height (LTH), trochlear height (TH) and medial trochlear height (MTH) were measured on four different sagittal planes. The capitellar width (CW), capitellar depth (CD), anterior lateral trochlear width (ALTW), posterior lateral trochlear width (PLTW), trochlear width (TW), anterior medial trochlear width (AMTW), posterior medial trochlear width (PMTW), trochlear depth (TD), anterior lateral trochlear depth (ALTD), posterior lateral trochlear depth (PLTD), anterior medial trochlear depth (AMTD), posterior medial trochlear depth (PMTD), and distal humeral width (W) were measured on the horizontal plane. The gender differences in measured parameters, correlations between data, and differences in H-FE angle from 90° were analyzed. Results In male, CH was 21.5± 1.3 mm, CW 17.5±1.1 mm, CD 10.8±0.9 mm, TW 25.1±2.2 mm, TH 17.3±1.5 mm, TD 17.5±1.4 mm, ALTW 7.7±1.2 mm, PLTW 12.5±1.6 mm, AMTW 12.4±1.6 mm, PMTW 9.8±2.0 mm, ALTD 10.0±0.8 mm, PLTD 16.3±1.4 mm, AMTD 12.9±1.4 mm, PMTD 13.2±1.4 mm, LTH 20.6±1.3 mm, MTH 25.0±2.4 mm, W 42.6±2.5 mm. The above parameters in female was 18.7±1.1 mm, 15.3±1.1 mm, 9.5±0.6 mm, 21.7±1.5 mm, 15.4±1.7 mm, 15.6±1.5 mm, 6.8±1.3 mm, 10.7±1.4 mm, 10.6±1.4 mm, 8.5±1.4 mm, 8.9±0.8 mm, 14.5±1.1 mm, 11.4±1.1 mm, 11.5±1.0 mm, 18.1±1.4 mm, 21.6±1.4 mm and 37.0±1.8 mm, respectively. All the above anatomical parameters in men were larger than those in women with statistically significant difference (P 0.05). All measurements except for the H-FE angle had a positive correlation with the articular width (0.335≤r≤0.928, P<0.05). The difference between the angle of the H-FE axis (87.6°±3.4°) and 90° was statistically significant (t=-7.287, P<0.05). Conclusion The size of the distal humerus in male is larger than that in female without difference in shape. Distal humerus width can be used as an indicator to measure the size of the distal humerus. The humeral shaft is more biased toward the radial side. Key words: Humerus; Arthroplasty, replacement, elbow; Prosthesis design; Morphology; Tomography, X-ray computed
目的探讨我国健康成人肱骨远端解剖特征。方法从图像存档与通信系统(PACS)中选取121例正常肘关节CT图像,在AW4.5工作站重建测量。冠状面和水平面由屈伸(FE)轴和肱骨轴确定,矢状面垂直于FE轴。在冠状面上测量肱骨髓腔轴线与肘关节FE轴夹角(H-FE角)。在4个不同矢状面上测量小头高度(CH)、外侧滑车高度(LTH)、滑车高度(TH)和内侧滑车高度(MTH)。在水平面上测量小头宽度(CW)、小头深度(CD)、前外侧滑车宽度(ALTW)、后外侧滑车宽度(PLTW)、滑车宽度(TW)、前内侧滑车宽度(AMTW)、后内侧滑车宽度(PMTW)、滑车深度(TD)、前外侧滑车深度(ALTD)、后外侧滑车深度(PLTD)、前内侧滑车深度(AMTD)、后内侧滑车深度(PMTD)、肱骨远端宽度(W)。分析了测量参数的性别差异、数据之间的相关性以及90°H-FE角度的差异。结果男性CH为21.5±1.3 mm, CW为17.5±1.1 mm, CD为10.8±0.9 mm, TW为25.1±2.2 mm, TH为17.3±1.5 mm, TD为17.5±1.4 mm, ALTW为7.7±1.2 mm, PLTW为12.5±1.6 mm, AMTW为12.4±1.6 mm, PMTW为9.8±2.0 mm, ALTD为10.0±0.8 mm, PLTD为16.3±1.4 mm, AMTD为12.9±1.4 mm, PMTD为13.2±1.4 mm, LTH为20.6±1.3 mm, MTH为25.0±2.4 mm, w42.6±2.5 mm。女性分别为18.7±1.1 mm、15.3±1.1 mm、9.5±0.6 mm、21.7±1.5 mm、15.4±1.7 mm、15.6±1.5 mm、6.8±1.3 mm、10.7±1.4 mm、10.6±1.4 mm、8.5±1.4 mm、8.9±0.8 mm、14.5±1.1 mm、11.4±1.1 mm、11.5±1.0 mm、18.1±1.4 mm、21.6±1.4 mm和37.0±1.8 mm。以上解剖参数男性均大于女性,差异有统计学意义(P < 0.05)。除H-FE角外,其余指标均与关节宽度呈正相关(0.335≤r≤0.928,P<0.05)。H-FE轴角度(87.6°±3.4°)与90°的差异有统计学意义(t=-7.287, P<0.05)。结论男性肱骨远端大小大于女性,但形态上无差异。肱骨远端宽度可作为衡量肱骨远端大小的指标。肱骨轴更偏向桡骨侧。关键词:肱骨;关节置换术、置换、肘关节;假体设计;形态;x线计算机断层扫描
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引用次数: 0
Arthroscopic fixation with figure of 8 suture versus ladder mesh suture for anterior cruciate ligament tibial avulsion fracture 关节镜下8字形缝合与梯网缝合治疗胫骨前交叉韧带撕脱骨折
Q4 Medicine Pub Date : 2020-02-01 DOI: 10.3760/CMA.J.ISSN.0253-2352.2020.03.003
Shi-jun Gao
Objective To compare the primary clinical results of arthroscopic figure of 8 suture and ladder mesh suture fixations in treating anterior cruciate ligament (ACL) tibial avulsion fractures. Methods From August 2013 to November 2016, a total of 37 patients with ACL tibial avulsion fracture who had closed epiphyses underwent arthroscopy. By the Meyers-McKeever-Zaricznyj classification, 10 cases were type II, 22 type III and 5 type IV. There were 25 cases in the figure of 8 suture fixation group with two No.2 high-strength sutures crossed to form a 8 figure to pull out and fix the fracture through the tibial tunnels, including 17 males and 8 females with an average age of 18.91±9.34 years (range 14-36 years). The ladder mesh suture fixation group with three No.2 high-strength sutures woven into a mesh to pull out and fix the fracture through the tibial tunnels had 12 cases, including 8 males and 4 females with an average age of 19.63±7.85 years (range 15-33 years). At the latest follow-up, the Lysholm and International Knee Documentation Committee (IKDC) scores were used to estimate knee joint function, while the Lachman test and Pivot-shift test were used to estimate knee joint instability. The operation duration, knee range of motion (ROM) and the number of case with flexion contracture were evaluated. Results All 37 cases were followed up. The average follow-up duration was 16.35±5.27 months (range 10-22 months) in figure of 8 suture fixation group and 14.06±7.18 months (range 10-21 months) in ladder mesh suture fixation group. In figure of 8 suture fixation group, the Lysholm and IKDC average scores were 95.86±5.74 and 90.53±4.61, respectively. However, they were 96.53±3.17 and 92.15±5.54 in ladder mesh suture fixation group with no significant difference between the two groups after operation (t=0.723, P=0.462; t=1.018, P=0.279). The percentage of negative Lachman test and Pivot-shift test in the figure of 8 suture group was 92% (23/25) . There was no significant difference in the negative rate in the ladder mesh suture fixation group 100% (12/12, χ2=0.904, P=0.265). The average operation duration of ladder mesh suture fixation group was 61.8±6.3 minutes, which was longer than that of figure of 8 suture fixation group 43.5±5.9 minutes (t=2.714, P=0.025). Flexion contracture of ≥5° occurred in 4 cases in the figure of 8 suture group and 0 case in the ladder mesh suture fixation group with significant difference between the two groups (χ2=0.450, P=0.032). Conclusion In treating ACL tibial avulsion fractures, arthroscopic figure of 8 suture fixation and ladder mesh suture fixation can achieve satisfied functional recovery and stability. The ladder mesh suture fixation can effectively achieve reduction of fracture fragments and knee flexion contracture. It may have more advantages in treating rotational type III and type IV comminuted fractures. However, some disadvantages in this technique, such as high technical requirements an
目的比较关节镜下8缝线与梯网缝线固定治疗前交叉韧带胫骨撕脱骨折的初步临床效果。方法2013年8月至2016年11月,对37例闭合性骨骺前交叉韧带胫骨撕脱骨折患者进行关节镜检查。根据Meyers-McKeever-Zaricznyj分类,II型10例,III型22例,IV型5例。8缝线固定组25例,两根2号高强度缝线交叉形成8字形,通过胫骨隧道拔出并固定骨折,其中男性17例,女性8例,平均年龄18.91±9.34岁(14-36岁)。梯网缝线固定组12例,其中男性8例,女性4例,平均年龄19.63±7.85岁(15-33岁)。在最新的随访中,Lysholm和国际膝关节文献委员会(IKDC)的评分被用于评估膝关节功能,而Lachman测试和Pivot移位测试被用于估计膝关节不稳定性。评估手术时间、膝关节活动范围(ROM)和屈曲挛缩病例数。结果37例均获得随访。8缝线固定组的平均随访时间为16.35±5.27个月(10-22个月),梯网缝线固定组为14.06±7.18个月(10-201个月)。在8缝线固定组中,Lysholm和IKDC的平均得分分别为95.86±5.74和90.53±4.61。梯网缝线固定组分别为96.53±3.17和92.15±5.54,两组术后差异无统计学意义(t=0.723,P=0.462;t=1.018,P=0.279),Lachman试验和Pivot shift试验阴性率在8缝线组中为92%(23/25)。梯网缝线固定组阴性率100%无显著性差异(12/12,χ2=0.904,P=0.265),比8缝线组延长43.5±5.9分钟(t=2.714,P=0.025)。8缝线组4例和梯网缝线固定组0例发生≥5°屈曲挛缩,两组差异有统计学意义(χ2=0.450,P=0.032),关节镜下8缝线固定和梯网缝线固定可以达到满意的功能恢复和稳定性。梯网缝合内固定可有效减少骨折碎片和膝关节屈曲挛缩。它在治疗III型和IV型旋转性粉碎性骨折方面可能更有优势。然而,必须考虑该技术的一些缺点,如技术要求高和操作时间长。关键词:关节镜检查;缝线;骨折内固定术;前交叉韧带
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引用次数: 0
Risk factors and clinical manifestations of head-neck wear in artificial hip joints 人工髋关节头颈磨损的危险因素及临床表现
Q4 Medicine Pub Date : 2020-02-01 DOI: 10.3760/CMA.J.ISSN.0253-2352.2020.03.007
Bo Li, Xing-yu Zhao, Yuan-Xin Cheng, Yu Han, W. Feng, Dongsong Li
At present, total hip arthroplasty (THA) is the primary treatment for hip diseases such as femoral head necrosis and developmental dysplasia of the hip. It has good effects in reducing pain and improving joint function. The appearance of modular hip prosthesis facilitates adjustment of limb length and femoral offset. However, the wear between the interface of hip prosthesis can lead to inflammatory pseudotumor, osteolysis and other adverse reactions. To explore the risk factors of wear between hip prosthesis interface is helpful to improve the design and manufacturing concept of the product, improve the product performance, help surgeons optimize the operation technology and reduce the impact of human factors on the wear of the prosthesis. Many literatures have reported the mechanism of wear between the head-acetabula interface of prosthesis. The mechanism of wear between the interfaces has been described relatively clearly. In addition to the head-acetabula interface, the wear between the head-neck interface is another major cause of unexplained pain around the joint and prosthesis loosening after hip replacement. Many factors affect head-neck wear. The design of prosthesis (such as prosthesis material and prosthesis taper), surgical technology (such as impact strength and prosthesis mismatch) and patient factors (such as age, gender and activity) have important impact on head-neck wear. Adverse reactions caused by head-neck wear have also been widely concerned. However, there is no considerable solution for wear prevention. Thus, we should optimize the design of prosthesis, improve the surgical technology, and guide the rehabilitation of patients to prevent wear. In order to improve the attention of joint surgeons, the present paper reviews the literatures and analyzes the risk factors of head-neck interface wear and the clinical manifestations caused by head-neck wear.
目前,全髋关节置换术(THA)是治疗股骨头坏死和髋关节发育不良等髋关节疾病的主要方法。它在减轻疼痛和改善关节功能方面有很好的效果。模块化髋关节假体的出现便于调整肢体长度和股骨偏移。然而,髋关节假体界面之间的磨损会导致炎性假瘤、骨溶解等不良反应。探讨髋关节假体界面磨损的危险因素,有助于提高产品的设计和制造理念,提高产品性能,帮助外科医生优化手术技术,减少人为因素对假体磨损的影响。许多文献报道了假体头-髋臼界面磨损的机理。界面之间的磨损机制已经被相对清楚地描述。除了头-髋臼界面外,头-颈界面之间的磨损是髋关节置换术后关节周围不明原因疼痛和假体松动的另一个主要原因。许多因素会影响头颈磨损。假体的设计(如假体材料和假体锥度)、手术技术(如冲击强度和假体不匹配)和患者因素(如年龄、性别和活动)对头颈部磨损有重要影响。头颈部磨损引起的不良反应也受到广泛关注。然而,对于磨损预防,没有相当大的解决方案。因此,我们应该优化假体的设计,提高手术技术,指导患者的康复,防止磨损。为了提高关节外科医生的重视程度,本文对文献进行了综述,分析了头颈部界面磨损的危险因素以及头颈部磨损引起的临床表现。
{"title":"Risk factors and clinical manifestations of head-neck wear in artificial hip joints","authors":"Bo Li, Xing-yu Zhao, Yuan-Xin Cheng, Yu Han, W. Feng, Dongsong Li","doi":"10.3760/CMA.J.ISSN.0253-2352.2020.03.007","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0253-2352.2020.03.007","url":null,"abstract":"At present, total hip arthroplasty (THA) is the primary treatment for hip diseases such as femoral head necrosis and developmental dysplasia of the hip. It has good effects in reducing pain and improving joint function. The appearance of modular hip prosthesis facilitates adjustment of limb length and femoral offset. However, the wear between the interface of hip prosthesis can lead to inflammatory pseudotumor, osteolysis and other adverse reactions. To explore the risk factors of wear between hip prosthesis interface is helpful to improve the design and manufacturing concept of the product, improve the product performance, help surgeons optimize the operation technology and reduce the impact of human factors on the wear of the prosthesis. Many literatures have reported the mechanism of wear between the head-acetabula interface of prosthesis. The mechanism of wear between the interfaces has been described relatively clearly. In addition to the head-acetabula interface, the wear between the head-neck interface is another major cause of unexplained pain around the joint and prosthesis loosening after hip replacement. Many factors affect head-neck wear. The design of prosthesis (such as prosthesis material and prosthesis taper), surgical technology (such as impact strength and prosthesis mismatch) and patient factors (such as age, gender and activity) have important impact on head-neck wear. Adverse reactions caused by head-neck wear have also been widely concerned. However, there is no considerable solution for wear prevention. Thus, we should optimize the design of prosthesis, improve the surgical technology, and guide the rehabilitation of patients to prevent wear. In order to improve the attention of joint surgeons, the present paper reviews the literatures and analyzes the risk factors of head-neck interface wear and the clinical manifestations caused by head-neck wear.","PeriodicalId":36405,"journal":{"name":"中华骨科杂志","volume":"40 1","pages":"178-185"},"PeriodicalIF":0.0,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46103308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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中华骨科杂志
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