Pub Date : 2022-05-15DOI: 10.18231/j.jdpo.2022.021
S. S. Giri, Amar Kumar, Sneha Singh
Colorectal polyps are unusual growths of epithelial tissue projecting from the mucosaof the large bowel. This study aimed to evaluate the frequency of histological pattern of polyp among colorectal polypectomy specimen concerning age, sex, size, and site and histopathological features and associated dysplasia. The study was done in the Pathology department in collaboration with the Gastroenterology Department on 115 patients. Biopsy was processed and histopathological features were studied with presence or absence of dysplasia. Most patients had constipation (40.87%) followed by rectal bleeding (40.00%) followed by pain abdomen and anemia. Male patients were 76(66.08%) followed by 39(33.91%) female patients. Among male patients most are of age range of 50-59yr (18.42%) and in females were of age range of 60-69yr. (25.64%). Grossly most polyp are of pedunculated shape (74.78%) followed by ulcerated type (13.04%) and least was of sessile appearance (12.17%). Most polyp were found in left side (descending colon: 40.87%) followed by rectum, ascending colon, sigmoid colon and transverse colon with least with caecum. Most Polyps size < 1 cm (90.40%) followed by size of polyp > 1 cm (9.60%). Regarding the histopathological evaluation of polyp we have reported tubular adenoma (53.91%) followed by hyperplastic polyp (19.13%) followed by tubulovillous adenoma (13.04%). Most of the polyp showed no dysplasia (94.64%) and dysplasia if seen both in tubular adenoma and tubulovillous adenoma. Colonoscopy is the most important tool in the detection of colonic polyp because of premalignant nature.
{"title":"Study of clinico-pathological characteristics of colonic polyp seen at a tertiary care hospital in East India","authors":"S. S. Giri, Amar Kumar, Sneha Singh","doi":"10.18231/j.jdpo.2022.021","DOIUrl":"https://doi.org/10.18231/j.jdpo.2022.021","url":null,"abstract":"Colorectal polyps are unusual growths of epithelial tissue projecting from the mucosaof the large bowel. This study aimed to evaluate the frequency of histological pattern of polyp among colorectal polypectomy specimen concerning age, sex, size, and site and histopathological features and associated dysplasia. The study was done in the Pathology department in collaboration with the Gastroenterology Department on 115 patients. Biopsy was processed and histopathological features were studied with presence or absence of dysplasia. Most patients had constipation (40.87%) followed by rectal bleeding (40.00%) followed by pain abdomen and anemia. Male patients were 76(66.08%) followed by 39(33.91%) female patients. Among male patients most are of age range of 50-59yr (18.42%) and in females were of age range of 60-69yr. (25.64%). Grossly most polyp are of pedunculated shape (74.78%) followed by ulcerated type (13.04%) and least was of sessile appearance (12.17%). Most polyp were found in left side (descending colon: 40.87%) followed by rectum, ascending colon, sigmoid colon and transverse colon with least with caecum. Most Polyps size < 1 cm (90.40%) followed by size of polyp > 1 cm (9.60%). Regarding the histopathological evaluation of polyp we have reported tubular adenoma (53.91%) followed by hyperplastic polyp (19.13%) followed by tubulovillous adenoma (13.04%). Most of the polyp showed no dysplasia (94.64%) and dysplasia if seen both in tubular adenoma and tubulovillous adenoma. Colonoscopy is the most important tool in the detection of colonic polyp because of premalignant nature.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131272971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-15DOI: 10.18231/j.jdpo.2022.036
Shushruta Mohanty, Lipika Behera, M. Mohapatro, Deepika Mishra, Minati Dehury
{"title":"Incidental detection of chorangiosis of placenta – Letter to editor","authors":"Shushruta Mohanty, Lipika Behera, M. Mohapatro, Deepika Mishra, Minati Dehury","doi":"10.18231/j.jdpo.2022.036","DOIUrl":"https://doi.org/10.18231/j.jdpo.2022.036","url":null,"abstract":"","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121189956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-15DOI: 10.18231/j.jdpo.2022.030
S. Sachdev, S. K. Mehra, T. Chettiankandy, M. A. Sardar
The present case report comprises of an unusual presentation of oral malignant melanoma which occurred in the furcation area of maxillary right first molar. A clinician may not suspect a malignant neoplasm and the histopathological examination of the tissue may be missed out in such cases. Without any obvious clinical or radiological features, the lesion mimicked a periapical granuloma. The diagnosis was achieved after a thorough histopathological examination and extensive immunohistochemistry panel to rule out other similar histopathological entities.
{"title":"An unusual presentation of oral malignant melanoma: Disguising as a periapical granuloma","authors":"S. Sachdev, S. K. Mehra, T. Chettiankandy, M. A. Sardar","doi":"10.18231/j.jdpo.2022.030","DOIUrl":"https://doi.org/10.18231/j.jdpo.2022.030","url":null,"abstract":"The present case report comprises of an unusual presentation of oral malignant melanoma which occurred in the furcation area of maxillary right first molar. A clinician may not suspect a malignant neoplasm and the histopathological examination of the tissue may be missed out in such cases. Without any obvious clinical or radiological features, the lesion mimicked a periapical granuloma. The diagnosis was achieved after a thorough histopathological examination and extensive immunohistochemistry panel to rule out other similar histopathological entities.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121734073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-15DOI: 10.18231/j.jdpo.2022.029
M. Mukherjee, Dhimoyee Ghatak, Asitava Deb Roy
Giant breast masses are of great concern as they have diagnostic as well as therapeutic challenges. Owing to the close morphological resemblance between giant fibroadenoma and Phyllodes tumor, here we are reporting a case of a young lady who was diagnosed with giant fibroadenoma clinically and by Fine Needle Aspiration Cytology (FNAC). Simple mastectomy was performed, and histopathology examination revealed a Giant Phyllodes. Thus, this report focuses on the rarity of the age of presentation, misleading clinical features and the diagnostic accuracy of FNAC compared to histopathology in differentiating these two close entities.
{"title":"Giant fibroadenoma and phyllodes tumour - A diagnostic conundrum","authors":"M. Mukherjee, Dhimoyee Ghatak, Asitava Deb Roy","doi":"10.18231/j.jdpo.2022.029","DOIUrl":"https://doi.org/10.18231/j.jdpo.2022.029","url":null,"abstract":"Giant breast masses are of great concern as they have diagnostic as well as therapeutic challenges. Owing to the close morphological resemblance between giant fibroadenoma and Phyllodes tumor, here we are reporting a case of a young lady who was diagnosed with giant fibroadenoma clinically and by Fine Needle Aspiration Cytology (FNAC). Simple mastectomy was performed, and histopathology examination revealed a Giant Phyllodes. Thus, this report focuses on the rarity of the age of presentation, misleading clinical features and the diagnostic accuracy of FNAC compared to histopathology in differentiating these two close entities.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129667309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-15DOI: 10.18231/j.jdpo.2022.033
K. Akhtar, F. Ekram, S. Usman, Lubna Fatma
Filariasis is a major public health problem in developing countries, and the diagnosis is conventionally made by demonstrating microfilariae in the peripheral blood smear. However, microfilariae have been incidentally detected in fine needle aspirates of various lesions in clinically unsuspected cases of filariasis with absence of microfilariae in the peripheral blood. Microfilariae in cytological smears of malignant neoplasms is a chance finding. Cytology can be an effective tool for detection of asymptomatic filariasis and malignancy, thus helping in disease eradication and mortality. There are reports of coexistence of microfilaria with Ewing’s sarcoma, squamous cell carcinoma of maxillary antrum and dentigerous cyst by different cytopathologists. Here we present a rare case of microfilariae in a cytological aspirate smear from left knee swelling with a malignant osteogenic tumor, osteosarcoma.
{"title":"Osteosarcoma with co-existent asymptomatic microfilaria-A rare cytological impression","authors":"K. Akhtar, F. Ekram, S. Usman, Lubna Fatma","doi":"10.18231/j.jdpo.2022.033","DOIUrl":"https://doi.org/10.18231/j.jdpo.2022.033","url":null,"abstract":"Filariasis is a major public health problem in developing countries, and the diagnosis is conventionally made by demonstrating microfilariae in the peripheral blood smear. However, microfilariae have been incidentally detected in fine needle aspirates of various lesions in clinically unsuspected cases of filariasis with absence of microfilariae in the peripheral blood. Microfilariae in cytological smears of malignant neoplasms is a chance finding. Cytology can be an effective tool for detection of asymptomatic filariasis and malignancy, thus helping in disease eradication and mortality. There are reports of coexistence of microfilaria with Ewing’s sarcoma, squamous cell carcinoma of maxillary antrum and dentigerous cyst by different cytopathologists. Here we present a rare case of microfilariae in a cytological aspirate smear from left knee swelling with a malignant osteogenic tumor, osteosarcoma.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129139238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-15DOI: 10.18231/j.jdpo.2022.025
M. Maurya, Manish Kumar, N. Akhtar
Alveolar soft part sarcoma (ASPS) is a very rare soft tissue tumor of unknown histogenesis and has propensity for recurrence and distant metastasis. It commonly occurs in the head neck region and on extremities in adolescents and young adults. Less number of cases have been reported in the scapular region so far. Till now, no definite treatment regime is available for ASPS; early diagnosis plays a pivotal role in its management and patient outcome. Here, we are presenting a case of 23 years old male presenting with a recurrent swelling in right scapular region. It was diagnosed as ASPS on the basis of radiology, histomorphology and immunohistochemistry.
摘要肺泡软组织肉瘤(Alveolar soft part sarcoma, ASPS)是一种非常罕见的软组织肿瘤，其组织起源不明，有复发及远处转移的倾向。它通常发生在头颈部和四肢的青少年和年轻人。到目前为止，在肩胛骨区域报告的病例较少。迄今为止，尚无明确的治疗方案;早期诊断在其管理和患者预后中起着关键作用。在这里，我们提出一个23岁的男性表现为复发性肿胀在右肩胛骨区域。经影像学、组织形态学及免疫组化检查，诊断为ASPS。
{"title":"Alveolar soft part sarcoma–presenting as an unusual scapular swelling- A rare case report","authors":"M. Maurya, Manish Kumar, N. Akhtar","doi":"10.18231/j.jdpo.2022.025","DOIUrl":"https://doi.org/10.18231/j.jdpo.2022.025","url":null,"abstract":"Alveolar soft part sarcoma (ASPS) is a very rare soft tissue tumor of unknown histogenesis and has propensity for recurrence and distant metastasis. It commonly occurs in the head neck region and on extremities in adolescents and young adults. Less number of cases have been reported in the scapular region so far. Till now, no definite treatment regime is available for ASPS; early diagnosis plays a pivotal role in its management and patient outcome. Here, we are presenting a case of 23 years old male presenting with a recurrent swelling in right scapular region. It was diagnosed as ASPS on the basis of radiology, histomorphology and immunohistochemistry.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129238023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-15DOI: 10.18231/j.jdpo.2022.027
K. Akhtar, Sadaf Abbas, A. Shams, Suhailar Rehman
Extrapulmonary tuberculosis is one of the major concern in developing countries. It presents with various clinical features, hence most of the times it is difficult to make diagnosis on the basis of single investigation. Multiple investigations should be done simultaneously for making appropriate diagnosis. We report a rare case of a 50 years old female, diagnosed as ovarian tuberculosis, who presented with complaints of dysmenorrhea, abnormal uterine bleeding and low grade fever for 4-6 months. Tuberculosis should always be kept in mind as the most common cause of granulomatous lesion in endemic regions.
{"title":"Ovarian tuberculosis-A rare case report","authors":"K. Akhtar, Sadaf Abbas, A. Shams, Suhailar Rehman","doi":"10.18231/j.jdpo.2022.027","DOIUrl":"https://doi.org/10.18231/j.jdpo.2022.027","url":null,"abstract":"Extrapulmonary tuberculosis is one of the major concern in developing countries. It presents with various clinical features, hence most of the times it is difficult to make diagnosis on the basis of single investigation. Multiple investigations should be done simultaneously for making appropriate diagnosis. We report a rare case of a 50 years old female, diagnosed as ovarian tuberculosis, who presented with complaints of dysmenorrhea, abnormal uterine bleeding and low grade fever for 4-6 months. Tuberculosis should always be kept in mind as the most common cause of granulomatous lesion in endemic regions.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124749813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-15DOI: 10.18231/j.jdpo.2022.022
Hetal Patel, P. Prajapati, Ripal J Shah, V. Harimoorthy
Internal Quality Control (IQC) describes steps taken by the blood centre to ensure that tests are performed correctly and as per the guidelines. Primary goal of Quality Control is transfusion of safe quality of blood components to give optimal benefit to patients. The aim of study was to ensure supply of safe and efficient blood component to patients.Quality control of blood components prepared between December 2019 to November 2021 were included in our study. Monthly Quality control (QC) of the blood components were done as per the national guideline, 1% of total components prepared or minimum 4 units. Packed red cell units were evaluated for haematocrit, random donor platelet concentrates for yield and fresh frozen plasma (FFP) and cryoprecipitate were evaluated for volume, factor VIII and fibrinogen concentrations.A total of 1302 units were tested for IQC. The mean hematocrit of RBC was 58.8%. In PLT, mean yield was 6.9 × 10/cu mm. Mean factor VIII and fibrinogen levels were found to be 377 IU/bag and 851.60 mg/bag in FFP respectively. Mean factor VIII and fibrinogen levels were found to be 311.81 IU/bag and 1694.4 mg/bag in cryoprecipitate respectively.In the present era, Quality Control is very important step in maintaining quality of blood components and the quality objectives of the blood centre, so that we ensure most efficient blood transfusion to patient. The IQC of blood components at our blood centre is in overall compliance and met recommended national standards. Implementation of standard operating procedures, accomplishment of standard guidelines, proper documentation with regular audit and staff competencies can improve the quality performance of the transfusion services.
内部质量控制(IQC)描述了血液中心为确保按照指导方针正确进行检测而采取的步骤。输血质量控制的首要目标是保证血液成分的安全质量，使患者获得最佳的利益。本研究的目的是确保为患者提供安全有效的血液成分。2019年12月至2021年11月制备的血液成分的质量控制纳入我们的研究。每月按国家标准进行血液成分的质量控制(QC)，占总成分的1%或最少4单位。评估红细胞压积，随机供体血小板浓缩物的产量，评估新鲜冷冻血浆(FFP)和冷冻沉淀的体积，因子VIII和纤维蛋白原浓度。共有1302个单位进行了IQC测试。平均红细胞比容为58.8%。在PLT中，平均产量为6.9 × 10/cu mm, FFP中平均因子VIII和纤维蛋白原含量分别为377 IU/袋和851.60 mg/袋。冷冻沉淀中因子VIII和纤维蛋白原的平均水平分别为311.81 IU/袋和1694.4 mg/袋。在当今时代，质量控制是维持血液成分质量和血液中心质量目标的重要步骤，以确保最有效地向患者输血。血液中心血液成分的IQC总体符合国家推荐标准。实施标准操作程序、完成标准指导方针、定期审计的适当文件和工作人员的能力可提高输血服务的质量。
{"title":"Internal quality control of blood & blood components - Two years study at a standalone blood centre, Ahmedabad","authors":"Hetal Patel, P. Prajapati, Ripal J Shah, V. Harimoorthy","doi":"10.18231/j.jdpo.2022.022","DOIUrl":"https://doi.org/10.18231/j.jdpo.2022.022","url":null,"abstract":"Internal Quality Control (IQC) describes steps taken by the blood centre to ensure that tests are performed correctly and as per the guidelines. Primary goal of Quality Control is transfusion of safe quality of blood components to give optimal benefit to patients. The aim of study was to ensure supply of safe and efficient blood component to patients.Quality control of blood components prepared between December 2019 to November 2021 were included in our study. Monthly Quality control (QC) of the blood components were done as per the national guideline, 1% of total components prepared or minimum 4 units. Packed red cell units were evaluated for haematocrit, random donor platelet concentrates for yield and fresh frozen plasma (FFP) and cryoprecipitate were evaluated for volume, factor VIII and fibrinogen concentrations.A total of 1302 units were tested for IQC. The mean hematocrit of RBC was 58.8%. In PLT, mean yield was 6.9 × 10/cu mm. Mean factor VIII and fibrinogen levels were found to be 377 IU/bag and 851.60 mg/bag in FFP respectively. Mean factor VIII and fibrinogen levels were found to be 311.81 IU/bag and 1694.4 mg/bag in cryoprecipitate respectively.In the present era, Quality Control is very important step in maintaining quality of blood components and the quality objectives of the blood centre, so that we ensure most efficient blood transfusion to patient. The IQC of blood components at our blood centre is in overall compliance and met recommended national standards. Implementation of standard operating procedures, accomplishment of standard guidelines, proper documentation with regular audit and staff competencies can improve the quality performance of the transfusion services.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125168529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-15DOI: 10.18231/j.jdpo.2022.032
T. Pathak, J. Sharma, A. Sarma, Abhijit Talukdar, A. Kataki
Xanthogranulomatous cholecystitis (XGC)- a rare pathological entity of gall bladder, is characterized by marked inflammatory infiltrates of macrophages and foam cells with proliferative fibrosis of the gall bladder wall. Although it is a benign condition, its radiological picture and intra operative findings mimic gall bladder carcinoma- leading to misdiagnosis in most cases. We report a case of XGC in a middle-aged lady who presented with a lump in right hypochondrium. Computed Tomography (CT) scans of the abdomen was inconclusive for her. A CT-guided Fine Needle Aspiration Cytology (FNAC) was obtained, where findings were suggestive of XGC which was finally confirmed on histopathological examination of the cholecystectomy specimen. The characteristic cytologic features of XGC on FNAC in this case helped differentiate it from malignancy, thereby sparing the patient a morbid radical surgery. Preoperative FNAC and intraoperative frozen section are valuable tools for differential diagnosis of XGC and help guide the surgeon towards a correct surgical approach.
{"title":"Xanthogranulomatous cholecystitis - Mimicking carcinoma gall bladder","authors":"T. Pathak, J. Sharma, A. Sarma, Abhijit Talukdar, A. Kataki","doi":"10.18231/j.jdpo.2022.032","DOIUrl":"https://doi.org/10.18231/j.jdpo.2022.032","url":null,"abstract":"Xanthogranulomatous cholecystitis (XGC)- a rare pathological entity of gall bladder, is characterized by marked inflammatory infiltrates of macrophages and foam cells with proliferative fibrosis of the gall bladder wall. Although it is a benign condition, its radiological picture and intra operative findings mimic gall bladder carcinoma- leading to misdiagnosis in most cases. We report a case of XGC in a middle-aged lady who presented with a lump in right hypochondrium. Computed Tomography (CT) scans of the abdomen was inconclusive for her. A CT-guided Fine Needle Aspiration Cytology (FNAC) was obtained, where findings were suggestive of XGC which was finally confirmed on histopathological examination of the cholecystectomy specimen. The characteristic cytologic features of XGC on FNAC in this case helped differentiate it from malignancy, thereby sparing the patient a morbid radical surgery. Preoperative FNAC and intraoperative frozen section are valuable tools for differential diagnosis of XGC and help guide the surgeon towards a correct surgical approach.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126342645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-15DOI: 10.18231/j.jdpo.2022.023
Anupama Raj K, S. P P, J. Ramakrishnan, Mahamood Aseef
Metastatic foci situated in dermal or subcutaneous tissue without the involvement of overlying skin, between the closest lymph node and primary tumor is called in transit metastasis. Although in transit metastasis has been commonly described in malignant melanoma, there are rare cases of squamous cell carcinomas, presenting with the same. It is an uncommon form of metastasis through lymphatics and is found in immunocompromised individuals. We present a case report of squamous cell carcinoma, presenting in an elderly male, as multiple nodules beneath skin. With this case, we highlight the variety of forms of spread in cutaneous squamous cell carcinoma and its prognostic importance.
{"title":"In- transit metastasis: Case report of a rare phenomenon in primary cutaneous squamous cell carcinoma","authors":"Anupama Raj K, S. P P, J. Ramakrishnan, Mahamood Aseef","doi":"10.18231/j.jdpo.2022.023","DOIUrl":"https://doi.org/10.18231/j.jdpo.2022.023","url":null,"abstract":"Metastatic foci situated in dermal or subcutaneous tissue without the involvement of overlying skin, between the closest lymph node and primary tumor is called in transit metastasis. Although in transit metastasis has been commonly described in malignant melanoma, there are rare cases of squamous cell carcinomas, presenting with the same. It is an uncommon form of metastasis through lymphatics and is found in immunocompromised individuals. We present a case report of squamous cell carcinoma, presenting in an elderly male, as multiple nodules beneath skin. With this case, we highlight the variety of forms of spread in cutaneous squamous cell carcinoma and its prognostic importance.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130759531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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