Pub Date : 2023-06-15DOI: 10.18231/j.jdpo.2023.023
Selvi Kalaivani, N. Siddaraju
Rosai-Dorfman disease (RDD) also known as sinus histiocytosis with massive lymphadenopathy is a rare disorder of histiocytes characterized histologically by intracellular engulfment of lymphocytes. It may occur in any age group, but is most commonly seen in children and young adults. It is characterized by painless, bilateral massive cervical lymphadenopathy. In approximately one-third of patients it can occur in a variety of extranodal sites where it can have abundant plasma cells and sclerosis. We present a rare case of RDD in a pregnant women who presented with unilateral cervical lymph node with features of RDD showing increase in plasma cells and sclerosis as seen in extranodal sites.
{"title":"Rosai-dorfman disease in pregnancy with rare presentations – A case report","authors":"Selvi Kalaivani, N. Siddaraju","doi":"10.18231/j.jdpo.2023.023","DOIUrl":"https://doi.org/10.18231/j.jdpo.2023.023","url":null,"abstract":"Rosai-Dorfman disease (RDD) also known as sinus histiocytosis with massive lymphadenopathy is a rare disorder of histiocytes characterized histologically by intracellular engulfment of lymphocytes. It may occur in any age group, but is most commonly seen in children and young adults. It is characterized by painless, bilateral massive cervical lymphadenopathy. In approximately one-third of patients it can occur in a variety of extranodal sites where it can have abundant plasma cells and sclerosis. We present a rare case of RDD in a pregnant women who presented with unilateral cervical lymph node with features of RDD showing increase in plasma cells and sclerosis as seen in extranodal sites.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125711540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-15DOI: 10.18231/j.jdpo.2023.015
Shugufta Shafi, Rakesh K Gupta, Rubeena Anjum, Mandeep Kaur
: The present study was aimed to determine the histopathological correlation in lesions of oral cavity in children aged 14 years and below received for diagnosis in the Oral Pathology Department of the Indira Gandhi Government Dental College Jammu, J&K. : The archives of the Department of Oral Pathology and Microbiology were retrospectively analyzed. Biopsy records of all oral lesions from pediatric patients, aged 0–14 years, from Department Of Oral and Maxillofacial Pathology & Oral Microbiology, Indira Gandhi Government Dental College Jammu, J&K, from 2011 to 2022 were considered. Descriptive statistical analysis and using computer software Pearson’s Chi‑square test was performed.: 36 biopsies (4.9%) belonged to pediatric population out of the total 727 biopsies that were received during the period. Females (64%) showed greater prevalence compared to males (36%). Affected age group seen were between10–14 years. The most common category of lesions diagnosed were cysts and the odontogenic tumors were the least seen. Mandible showed more predilection compared to maxilla in jaws which was most common location involved, followed by the gingiva, palate, lower lip and labial mucosa. On comparing the histopathological diagnosis, dentigerous cysts (22%) were the most common followed by radicular cysts (17%), fibrous hyperplasia (14%), pyogenic granuloma (11%), central giant cell granuloma (8%), hyperplasia of minor salivary glands (5.6%) and percentage of aneurysmal bone cyst, peripheral giant cell granuloma, peripheral ossifying fibroma, central ossifying fibroma, juvenile ossifying fibroma, cementoblastoma, ameloblastoma and necrotic bone all was equal (2.8%). A statistically significant association of age and gender was seen with the category of the lesion.:The lesions were more common in the mandible with a female predilection and in age group >10 years. The majority of oral and maxillofacial lesions detected in pediatric population were benign similar to the previous reports.
{"title":"Histopathological correlation in oral biopsies in clinically diagnosed pediatric oral lesions: A 12-year institutional archival study","authors":"Shugufta Shafi, Rakesh K Gupta, Rubeena Anjum, Mandeep Kaur","doi":"10.18231/j.jdpo.2023.015","DOIUrl":"https://doi.org/10.18231/j.jdpo.2023.015","url":null,"abstract":": The present study was aimed to determine the histopathological correlation in lesions of oral cavity in children aged 14 years and below received for diagnosis in the Oral Pathology Department of the Indira Gandhi Government Dental College Jammu, J&K. : The archives of the Department of Oral Pathology and Microbiology were retrospectively analyzed. Biopsy records of all oral lesions from pediatric patients, aged 0–14 years, from Department Of Oral and Maxillofacial Pathology & Oral Microbiology, Indira Gandhi Government Dental College Jammu, J&K, from 2011 to 2022 were considered. Descriptive statistical analysis and using computer software Pearson’s Chi‑square test was performed.: 36 biopsies (4.9%) belonged to pediatric population out of the total 727 biopsies that were received during the period. Females (64%) showed greater prevalence compared to males (36%). Affected age group seen were between10–14 years. The most common category of lesions diagnosed were cysts and the odontogenic tumors were the least seen. Mandible showed more predilection compared to maxilla in jaws which was most common location involved, followed by the gingiva, palate, lower lip and labial mucosa. On comparing the histopathological diagnosis, dentigerous cysts (22%) were the most common followed by radicular cysts (17%), fibrous hyperplasia (14%), pyogenic granuloma (11%), central giant cell granuloma (8%), hyperplasia of minor salivary glands (5.6%) and percentage of aneurysmal bone cyst, peripheral giant cell granuloma, peripheral ossifying fibroma, central ossifying fibroma, juvenile ossifying fibroma, cementoblastoma, ameloblastoma and necrotic bone all was equal (2.8%). A statistically significant association of age and gender was seen with the category of the lesion.:The lesions were more common in the mandible with a female predilection and in age group >10 years. The majority of oral and maxillofacial lesions detected in pediatric population were benign similar to the previous reports.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124456920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-15DOI: 10.18231/j.jdpo.2023.016
Ripal J Shah, P. Prajapati, Disha A. Patel, V. Harimoorthy
Red Cells, Fresh Frozen Plasma (FFP) and Platelets (RDP/SDP) prepared from donors with group O may have high titers of anti-A, anti-B and/or anti-A,B antibodies. When such components given to non-group O patients, this high titre can result in haemolytic transfusion reactions (HTRs). Such group O donors are generally termed ‘high-titer group O donors. Significant amounts of ABO antigen being present on the platelet surface and anti-ABO iso-agglutinins being present in the donor’s plasma, Platelet transfusions need to take into account the issues. Although relatively rare, but acute intravascular haemolytic transfusion reaction has been caused by passive transfer of anti-A and anti-B antibodies, present in group O donors. This study aimed to identify the prevalence of high titre antibodies in group O donors. Thus, titre are performed in randomly selected group O donors from different gender and age group to identify best available source of products for Platelet and follow up transfusions.: Randomly selected 100 O blood group donors were included in the study. Samples from these donors were tested for ABO antibody (both IgM and IgG) titres using conventional tube technique at RT and 37°C at Indirect Antiglobulin phase. Statistical analysis was performed using two sample t-test and anova test.Donors included in the present study were mainly male (85%) donors. ABO antibody titres ranged from 0 to 2048. In the present study, Anti-B (IgG) titer is significantly higher than other antibodies in both genders. There are a large proportion of group O donors having high titres of antibodies and hence a routine pretransfusion screening for such antibodies can prevent the development of hemolytic transfusion reaction by issuing only low titre components for out of group transfusions. Each Blood Transfusion Service should establish a policy for testing and issue of group O platelets to non-O group recipient to avoid chances of development of adverse transfusion reaction.
{"title":"Role of antibody screening in high titre group O donors","authors":"Ripal J Shah, P. Prajapati, Disha A. Patel, V. Harimoorthy","doi":"10.18231/j.jdpo.2023.016","DOIUrl":"https://doi.org/10.18231/j.jdpo.2023.016","url":null,"abstract":"Red Cells, Fresh Frozen Plasma (FFP) and Platelets (RDP/SDP) prepared from donors with group O may have high titers of anti-A, anti-B and/or anti-A,B antibodies. When such components given to non-group O patients, this high titre can result in haemolytic transfusion reactions (HTRs). Such group O donors are generally termed ‘high-titer group O donors. Significant amounts of ABO antigen being present on the platelet surface and anti-ABO iso-agglutinins being present in the donor’s plasma, Platelet transfusions need to take into account the issues. Although relatively rare, but acute intravascular haemolytic transfusion reaction has been caused by passive transfer of anti-A and anti-B antibodies, present in group O donors. This study aimed to identify the prevalence of high titre antibodies in group O donors. Thus, titre are performed in randomly selected group O donors from different gender and age group to identify best available source of products for Platelet and follow up transfusions.: Randomly selected 100 O blood group donors were included in the study. Samples from these donors were tested for ABO antibody (both IgM and IgG) titres using conventional tube technique at RT and 37°C at Indirect Antiglobulin phase. Statistical analysis was performed using two sample t-test and anova test.Donors included in the present study were mainly male (85%) donors. ABO antibody titres ranged from 0 to 2048. In the present study, Anti-B (IgG) titer is significantly higher than other antibodies in both genders. There are a large proportion of group O donors having high titres of antibodies and hence a routine pretransfusion screening for such antibodies can prevent the development of hemolytic transfusion reaction by issuing only low titre components for out of group transfusions. Each Blood Transfusion Service should establish a policy for testing and issue of group O platelets to non-O group recipient to avoid chances of development of adverse transfusion reaction.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129126924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-15DOI: 10.18231/j.jdpo.2023.017
Rachana Lakhe, Amrutraj Patil, R. Doshi, P. Doshi, Milind Kesarkhane, R. Nimbargi
Colorectal cancer is the third most common cancer in both men and women. Environmental and genetic factors play a role in the development of colorectal carcinomaThe majority of colorectal cancers are sporadic, with hereditary cancer syndrome accounting for 10% of cases. Precursor lesions like adenoma that transform into adenocarcinoma cause the majority of colorectal cancers. : A total of 72 of colorectal malignancies were studied for histopathological features. The histologic features were studied for site, grade, tumor -infiltrating lymphocytes, Crohn -like lymphocytic reaction, mucinous histology, signet ring cell histology, and medullary growth pattern.: The mean age of the patients was 59.52 ± 11.80 years with M:F 1.76:1. Light microscopy showed TILs in 16 (22.2%) patients, followed by mucinous areas in 5 (6.9%), crohn like lymphocytic reaction in 4 (5.6%) and signet ring morphology in 2 (2.8%) patients.This study concludes that colorectal carcinomas are more common in 5th and 6th decade of life with slight male preponderance. The most common malignant lesion being moderately differentiated adenocarcinomas. This study highlights age and gender prevalence, as well as histopathological characteristics of colorectal carcinomas in this demographic region .
{"title":"Spectrum of Colorectal Adenocarcinomas: A 4 year experience in a tertiary care centre from Western Maharashtra","authors":"Rachana Lakhe, Amrutraj Patil, R. Doshi, P. Doshi, Milind Kesarkhane, R. Nimbargi","doi":"10.18231/j.jdpo.2023.017","DOIUrl":"https://doi.org/10.18231/j.jdpo.2023.017","url":null,"abstract":"Colorectal cancer is the third most common cancer in both men and women. Environmental and genetic factors play a role in the development of colorectal carcinomaThe majority of colorectal cancers are sporadic, with hereditary cancer syndrome accounting for 10% of cases. Precursor lesions like adenoma that transform into adenocarcinoma cause the majority of colorectal cancers. : A total of 72 of colorectal malignancies were studied for histopathological features. The histologic features were studied for site, grade, tumor -infiltrating lymphocytes, Crohn -like lymphocytic reaction, mucinous histology, signet ring cell histology, and medullary growth pattern.: The mean age of the patients was 59.52 ± 11.80 years with M:F 1.76:1. Light microscopy showed TILs in 16 (22.2%) patients, followed by mucinous areas in 5 (6.9%), crohn like lymphocytic reaction in 4 (5.6%) and signet ring morphology in 2 (2.8%) patients.This study concludes that colorectal carcinomas are more common in 5th and 6th decade of life with slight male preponderance. The most common malignant lesion being moderately differentiated adenocarcinomas. This study highlights age and gender prevalence, as well as histopathological characteristics of colorectal carcinomas in this demographic region .","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114051514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-15DOI: 10.18231/j.jdpo.2023.005
M. Lakhani, M. M. Shah, H. Parikh, G. Ramchandani, Kuldeep Pravinbhai Prajapati
CNS lesions have variety in an aetiology like infections, neoplastic, inflammatory and any vascular malformation. With advance in neuro-imaging we can early recognise and diagnose it. Majority of patients with CNS neoplasms present clinically with headache, vomiting and/or seizures confusing with non-neoplastic lesions. So to differentiate between neoplastic and non-neoplastic lesions histopathological examination which is gold standard is required.In period between January 2019 to April 2021, we have received total 69 CNS lesions biopsy and histopathological examination was done and they are classified according to WHO classification. All the data were collected retrospectively from Department of Pathology, Medical College, Baroda.Patient’s age ranged from 45 days to 72 years. Out of total 69 cases, there were 15 were non-neoplastic lesions and 54 were neoplastic lesions. Among neoplastic lesions, 50 cases were primary CNS tumors and 04 cases were metastatic tumors.Low grade CNS lesions were found to progress to high grade CNS tumours. Proper clinical history, neuroimaging study and exact histopathological diagnosis is essential to predict prognosis and treatment.
{"title":"A histopathological spectrum of central nervous system lesion: Tertiary care hospital","authors":"M. Lakhani, M. M. Shah, H. Parikh, G. Ramchandani, Kuldeep Pravinbhai Prajapati","doi":"10.18231/j.jdpo.2023.005","DOIUrl":"https://doi.org/10.18231/j.jdpo.2023.005","url":null,"abstract":"CNS lesions have variety in an aetiology like infections, neoplastic, inflammatory and any vascular malformation. With advance in neuro-imaging we can early recognise and diagnose it. Majority of patients with CNS neoplasms present clinically with headache, vomiting and/or seizures confusing with non-neoplastic lesions. So to differentiate between neoplastic and non-neoplastic lesions histopathological examination which is gold standard is required.In period between January 2019 to April 2021, we have received total 69 CNS lesions biopsy and histopathological examination was done and they are classified according to WHO classification. All the data were collected retrospectively from Department of Pathology, Medical College, Baroda.Patient’s age ranged from 45 days to 72 years. Out of total 69 cases, there were 15 were non-neoplastic lesions and 54 were neoplastic lesions. Among neoplastic lesions, 50 cases were primary CNS tumors and 04 cases were metastatic tumors.Low grade CNS lesions were found to progress to high grade CNS tumours. Proper clinical history, neuroimaging study and exact histopathological diagnosis is essential to predict prognosis and treatment.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128407075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-15DOI: 10.18231/j.jdpo.2023.003
S. Raj, Alka Yadav
Parasitic infection becomes an unsolved problem in using of automated instruments for urinalysis. Most common parasitic infections described in literature are Trichomonas vaginalis, Schistosoma hematobium and Microfilaria. Other rare organisms are Balantidium coli and Paramecium. The main purpose of this article is to raise the awareness in pathologists and clinicians on the importance of cytological evaluation of urine. This study was done to find the associations between the age and point prevalence of organisms in our zone in the last 6 years. Identification of parasites in centrifuged deposits of urine sediment is a relatively rare occurrence in clinical practice. A fairly wide morphological spectrum of parasites may be diagnosed through microscopic examination of centrifuged urine sediment. They may present with symptoms like pyuria, hematuria, diarrhoea, burning micturition, itching and morphological awareness helps in prompt and effective management in most cases.
{"title":"Parasites observed in urine sediments: A learning from incidental rare species","authors":"S. Raj, Alka Yadav","doi":"10.18231/j.jdpo.2023.003","DOIUrl":"https://doi.org/10.18231/j.jdpo.2023.003","url":null,"abstract":"Parasitic infection becomes an unsolved problem in using of automated instruments for urinalysis. Most common parasitic infections described in literature are Trichomonas vaginalis, Schistosoma hematobium and Microfilaria. Other rare organisms are Balantidium coli and Paramecium. The main purpose of this article is to raise the awareness in pathologists and clinicians on the importance of cytological evaluation of urine. This study was done to find the associations between the age and point prevalence of organisms in our zone in the last 6 years. Identification of parasites in centrifuged deposits of urine sediment is a relatively rare occurrence in clinical practice. A fairly wide morphological spectrum of parasites may be diagnosed through microscopic examination of centrifuged urine sediment. They may present with symptoms like pyuria, hematuria, diarrhoea, burning micturition, itching and morphological awareness helps in prompt and effective management in most cases.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121032748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-15DOI: 10.18231/j.jdpo.2023.008
S. Raj
Umbilical tumours or lesions are rare; therefore, it is of outmost importance to navigate every umbilical nodule or growth cautiously. Only 10 cases have been reported to date. The present case has been diagnosed as congenital EIC in the umbilicus, the first time this has been reported in the archives.A 5 year old female child with umbilical nodular swelling since birth presented to the surgery OPD.A clinical diagnosis of "umbilical adenoma" was made. An excisional biopsy with abdominoplasty was done under general anaesthesia, and the specimen was submitted for HPE. On gross examination, we received an umbilical stump measuring 1 x 1 x 0.4 cm. A raised, firm nodular swelling was noted on the umbilical knot along with keratin debris. On cut, it showed a well-circumscribed, tiny gray-white nodule measuring 0.5 x 0.4 cm. On microscopic examination, a diagnosis of “Umbilical Epidermal Inclusion Cyst”was given.: Umbilical EIC is a rare entity that may present as an umbilical nodule and is detected in every age group with a female preponderance. Underlying etiopathogenesis can be congenital, idiopathic, or post-iatrogenic. Over 80% of the umbilical EIC is located above the fascia. The histopathological examination is the only modality that leads to an exact diagnosis and is considered the “gold standard” for detection of commonest cyst occurring in the rare site.
脐部肿瘤或病变罕见;因此，小心地检查每一个脐结节或生长是非常重要的。迄今仅报告了10例。本病例被诊断为先天性脐部EIC，这是首次在档案中报道。一名5岁女童出生后脐带结节性肿胀向外科OPD提出。临床诊断为“脐腺瘤”。在全身麻醉下进行切除活检和腹部成形术，并将标本提交HPE。在大体检查中，我们收到了1 x 1 x 0.4 cm的脐带残端。脐结处可见凸起、坚固的结节性肿胀，伴角蛋白碎片。切面可见一个界限分明的灰白色小结节，大小为0.5 x 0.4 cm。镜检诊断为“脐表皮包涵体囊肿”。脐带EIC是一种罕见的实体，可能表现为脐带结节，在每个年龄组中都可以检测到，以女性为主。潜在的发病机制可以是先天性的、特发性的或医后性的。超过80%的脐带EIC位于筋膜上方。组织病理学检查是导致准确诊断的唯一方式，被认为是在罕见部位发现最常见囊肿的“金标准”。
{"title":"Congenital umbilical epidermal inclusion cyst masquerading as raspberry tumor– A common cyst in rare site","authors":"S. Raj","doi":"10.18231/j.jdpo.2023.008","DOIUrl":"https://doi.org/10.18231/j.jdpo.2023.008","url":null,"abstract":"Umbilical tumours or lesions are rare; therefore, it is of outmost importance to navigate every umbilical nodule or growth cautiously. Only 10 cases have been reported to date. The present case has been diagnosed as congenital EIC in the umbilicus, the first time this has been reported in the archives.A 5 year old female child with umbilical nodular swelling since birth presented to the surgery OPD.A clinical diagnosis of \"umbilical adenoma\" was made. An excisional biopsy with abdominoplasty was done under general anaesthesia, and the specimen was submitted for HPE. On gross examination, we received an umbilical stump measuring 1 x 1 x 0.4 cm. A raised, firm nodular swelling was noted on the umbilical knot along with keratin debris. On cut, it showed a well-circumscribed, tiny gray-white nodule measuring 0.5 x 0.4 cm. On microscopic examination, a diagnosis of “Umbilical Epidermal Inclusion Cyst”was given.: Umbilical EIC is a rare entity that may present as an umbilical nodule and is detected in every age group with a female preponderance. Underlying etiopathogenesis can be congenital, idiopathic, or post-iatrogenic. Over 80% of the umbilical EIC is located above the fascia. The histopathological examination is the only modality that leads to an exact diagnosis and is considered the “gold standard” for detection of commonest cyst occurring in the rare site.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126033468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-15DOI: 10.18231/j.jdpo.2023.004
Bharathi
To study the haemoglobin levels among middle aged working women in kancheepuram district tamilnadu To assess the haemoglobin levels in working women of age group ranging from 25 to 65 years using hemocue 301 analyser. To analyse the clinical signs and symptoms, grade the anemia and to find the association with nutritional and socio economic status of the participants. We studied the haemoglobin levels of 198 working women of age group ranging from 25 to 65 years using hemocue 301 analyser. Women were the residents of Kovur, Kancheepuram district, Tamilnadu.. Institutional ethical committee clearance was obtained. We assessed the Hb level in capillary blood by finger prick method using disposable single use sterile lancets. We observed that 31% of our study participants hemoglobin values less than 12g/dl. We observed that 14% of women had mild anemia, 16% had moderate anemia and 1% had severe anemia. Prevalence of anemia among working women is high in India. Haemoglobin status of women is influenced by their diet, working environment, socio economic status and other associated diseases. We emphasize through our study on routine screening women for anemia and Iron and Folate supplements should be given to them frequently .
{"title":"Study of haemoglobin levels among working women in Kancheepuram district Tamil Nadu","authors":"Bharathi","doi":"10.18231/j.jdpo.2023.004","DOIUrl":"https://doi.org/10.18231/j.jdpo.2023.004","url":null,"abstract":"To study the haemoglobin levels among middle aged working women in kancheepuram district tamilnadu To assess the haemoglobin levels in working women of age group ranging from 25 to 65 years using hemocue 301 analyser. To analyse the clinical signs and symptoms, grade the anemia and to find the association with nutritional and socio economic status of the participants. We studied the haemoglobin levels of 198 working women of age group ranging from 25 to 65 years using hemocue 301 analyser. Women were the residents of Kovur, Kancheepuram district, Tamilnadu.. Institutional ethical committee clearance was obtained. We assessed the Hb level in capillary blood by finger prick method using disposable single use sterile lancets. We observed that 31% of our study participants hemoglobin values less than 12g/dl. We observed that 14% of women had mild anemia, 16% had moderate anemia and 1% had severe anemia. Prevalence of anemia among working women is high in India. Haemoglobin status of women is influenced by their diet, working environment, socio economic status and other associated diseases. We emphasize through our study on routine screening women for anemia and Iron and Folate supplements should be given to them frequently .","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126544351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-15DOI: 10.18231/j.jdpo.2023.006
Kirtijit Chakma, Rashmi Kuswaha, G. Yadav, U. Singh, W. Ali, Ashutosh Kumar, S. Verma, N. Verma, T. Deori
Reticulocytes are immature, non-nucleated RBCs that still contain RNA. It provides useful information about the capacity of the bone marrow to synthesize and release red cells in response to anemia and helps to distinguish between decreased RBC production and enhanced peripheral destruction. A prospective study was done between thalassemia and iron deficiency anemia cases. The duration of the study was 1 year where 139 cases were included. In our study, a total of 139 patients are included out of which 94 cases were of Thalassemia and 45 cases of Iron deficiency anemia. Measurement of complete blood count (CBC) with reticulocyte fractions was done in the SYSMEX XN-550 system and for serum ferritin, Architect iSystem was used. This study demonstrates the cut-off value of IRF for detecting Thalassemia trait as 15.85-21.50%, IDA was >21.50% and for Thalassemia major it was < 15.85%. The LFR% optimum cut-off for detecting Thalassemia trait was estimated to be 83.1-84.2%, IDA <83.1%and for Thalassemia major it was > 84.2%. The MFR% optimum cut-off for detecting Thalassemia trait was estimated to be <12.9%, IDA was >13.25% and for Thalassemia major it was 12.9-13.25%. The HFR% optimum cut-off for detecting Thalassemia trait was estimated to be 2.4-5.3%, IDA was >5.3%and for Thalassemia major it was < 2.4%. The use of new hematological parameters and doing further comparative-based studies will help in differentiating various types of anemia and give knowledge of physiopathology of the underlying disease.
{"title":"Novel reticulocyte parameters in thalassemia and iron deficiency anemia","authors":"Kirtijit Chakma, Rashmi Kuswaha, G. Yadav, U. Singh, W. Ali, Ashutosh Kumar, S. Verma, N. Verma, T. Deori","doi":"10.18231/j.jdpo.2023.006","DOIUrl":"https://doi.org/10.18231/j.jdpo.2023.006","url":null,"abstract":"Reticulocytes are immature, non-nucleated RBCs that still contain RNA. It provides useful information about the capacity of the bone marrow to synthesize and release red cells in response to anemia and helps to distinguish between decreased RBC production and enhanced peripheral destruction. A prospective study was done between thalassemia and iron deficiency anemia cases. The duration of the study was 1 year where 139 cases were included. In our study, a total of 139 patients are included out of which 94 cases were of Thalassemia and 45 cases of Iron deficiency anemia. Measurement of complete blood count (CBC) with reticulocyte fractions was done in the SYSMEX XN-550 system and for serum ferritin, Architect iSystem was used. This study demonstrates the cut-off value of IRF for detecting Thalassemia trait as 15.85-21.50%, IDA was >21.50% and for Thalassemia major it was < 15.85%. The LFR% optimum cut-off for detecting Thalassemia trait was estimated to be 83.1-84.2%, IDA <83.1%and for Thalassemia major it was > 84.2%. The MFR% optimum cut-off for detecting Thalassemia trait was estimated to be <12.9%, IDA was >13.25% and for Thalassemia major it was 12.9-13.25%. The HFR% optimum cut-off for detecting Thalassemia trait was estimated to be 2.4-5.3%, IDA was >5.3%and for Thalassemia major it was < 2.4%. The use of new hematological parameters and doing further comparative-based studies will help in differentiating various types of anemia and give knowledge of physiopathology of the underlying disease.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133985143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-15DOI: 10.18231/j.jdpo.2023.012
N. Banerjee, Devmalya Banerjee, S. Bhattacharya, Sourav Sarkar, Nilay Biswas
Myofibroblasts were first detected in the granulation tissue and low-grade myofibroblastic sarcoma has now been recognized as a distinct entity. It has an indolent clinical course and distant metastasis is very rare. Hence surgical excision is the mainstay of the treatment. However, this tumor morphologically mimics other relatively high-grade soft tissue sarcomas, so distinguishing them is of utmost importance. Here we report, a 22-year-old young girl presented with neck pain and a slowly growing mass in the cervical paraspinal region. The patient was managed by wide local excision and the specimen was examined thoroughly. After considering all the features diagnosis of low-grade myofibroblastic sarcoma was offered.
{"title":"Low grade myofibroblastic sarcoma in paraspinal location: A case report with review of literature","authors":"N. Banerjee, Devmalya Banerjee, S. Bhattacharya, Sourav Sarkar, Nilay Biswas","doi":"10.18231/j.jdpo.2023.012","DOIUrl":"https://doi.org/10.18231/j.jdpo.2023.012","url":null,"abstract":"Myofibroblasts were first detected in the granulation tissue and low-grade myofibroblastic sarcoma has now been recognized as a distinct entity. It has an indolent clinical course and distant metastasis is very rare. Hence surgical excision is the mainstay of the treatment. However, this tumor morphologically mimics other relatively high-grade soft tissue sarcomas, so distinguishing them is of utmost importance. Here we report, a 22-year-old young girl presented with neck pain and a slowly growing mass in the cervical paraspinal region. The patient was managed by wide local excision and the specimen was examined thoroughly. After considering all the features diagnosis of low-grade myofibroblastic sarcoma was offered.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133775917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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