Pub Date : 2023-01-15DOI: 10.18231/j.jdpo.2022.066
Himachal Mishra, Manika Alexander
Hibernoma is a rare benign tumor that originates from brown fat. Hibernoma is thought to arise from areas containing residual brown fat like- the interscapular area, axilla, neck, chest, abdominal cavity, and retroperitoneum. The incidence of this rare tumor has very rarely been reported to occur over the forehead. Being a benign tumor, no association of malignant transformation or metastasis has been reported. A 23-year-old male presented with a complaint of a painless non-progressive swelling over the forehead for the past 6 months. On examination, the swelling was 2x2 cm, soft, mobile, non-tender, and non-pulsatile with no skin changes. FNAC did which shows sheets and clusters of adipocytes with abundant foamy cytoplasm and reported as “Hibernoma”. The patient has been asked to follow up and for the last 1 year, the tumor is still non-progressive with no pressure symptoms and hence has not undergone surgery. Hibernoma is a rare benign tumor of brown fat tissue which constitutes only 1.6% of benign lipomatous tumors but their actual prevalence is still unknown. This tumor very rarely may occur in the forehead area although incidence over the forehead has rarely been reported. Since this tumor is slow growing, painless non-progressive; it mostly presents as an asymptomatic tumor. It has to be included in the differential diagnosis of adipocyte-containing tumors to prevent false treatment.
{"title":"Hibernoma-A rare tumor on rare site","authors":"Himachal Mishra, Manika Alexander","doi":"10.18231/j.jdpo.2022.066","DOIUrl":"https://doi.org/10.18231/j.jdpo.2022.066","url":null,"abstract":"Hibernoma is a rare benign tumor that originates from brown fat. Hibernoma is thought to arise from areas containing residual brown fat like- the interscapular area, axilla, neck, chest, abdominal cavity, and retroperitoneum. The incidence of this rare tumor has very rarely been reported to occur over the forehead. Being a benign tumor, no association of malignant transformation or metastasis has been reported. A 23-year-old male presented with a complaint of a painless non-progressive swelling over the forehead for the past 6 months. On examination, the swelling was 2x2 cm, soft, mobile, non-tender, and non-pulsatile with no skin changes. FNAC did which shows sheets and clusters of adipocytes with abundant foamy cytoplasm and reported as “Hibernoma”. The patient has been asked to follow up and for the last 1 year, the tumor is still non-progressive with no pressure symptoms and hence has not undergone surgery. Hibernoma is a rare benign tumor of brown fat tissue which constitutes only 1.6% of benign lipomatous tumors but their actual prevalence is still unknown. This tumor very rarely may occur in the forehead area although incidence over the forehead has rarely been reported. Since this tumor is slow growing, painless non-progressive; it mostly presents as an asymptomatic tumor. It has to be included in the differential diagnosis of adipocyte-containing tumors to prevent false treatment.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117262221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-15DOI: 10.18231/j.jdpo.2022.060
Shilpa Mishra, R. Patkar, A. Neelakantan
Villous adenomas are known to occur in gastrointestinal tract; however, they are very rare in female genital tract. The pathogenesis is unclear but their origin from cloacal remnants has been hypothesized. Here we report a rare incidental case of primary villous adenoma with high grade dysplasia arising from vaginal vault in a 28-year-old female who presented with abnormal vaginal bleeding. The importance of reporting this lies in its pre-malignant behaviour and benign looking clinical appearance.
{"title":"Primary vaginal villous adenoma – A rare case report","authors":"Shilpa Mishra, R. Patkar, A. Neelakantan","doi":"10.18231/j.jdpo.2022.060","DOIUrl":"https://doi.org/10.18231/j.jdpo.2022.060","url":null,"abstract":"Villous adenomas are known to occur in gastrointestinal tract; however, they are very rare in female genital tract. The pathogenesis is unclear but their origin from cloacal remnants has been hypothesized. Here we report a rare incidental case of primary villous adenoma with high grade dysplasia arising from vaginal vault in a 28-year-old female who presented with abnormal vaginal bleeding. The importance of reporting this lies in its pre-malignant behaviour and benign looking clinical appearance.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123047885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-15DOI: 10.18231/j.jdpo.2022.059
Nidhi Rajendra, Subbaiah Ramanathan, V. Ashok, Srivalli BS
Fanconi anemia (FA) is a genetically heterogenous rare autosomal recessive disorder. Mutations in FANCA gene are the most frequent among FA patients accounting for 60-65%. FA is characterised by congenital malformations, progressive bone marrow failure (BMF) and increased risk of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). The risk of developing hematological abnormalities in FA patients is around 98% by 40 years of age. The risk of clonal cytogenetic abnormalities during BMF is around 67% by 30 years of age and risk of developing MDS or AML is 52% by 40 years of age. The frequent chromosomal abnormalities are 1q+, monosomy 7 and gains of 3q. Partial duplications/triplications of chromosome 1q are known to represent a nonrandom chromosomal anomaly in myeloid disorders.
{"title":"Rare cytogenetic abnormalities in MDS evolving from fanconi anemia-A case report","authors":"Nidhi Rajendra, Subbaiah Ramanathan, V. Ashok, Srivalli BS","doi":"10.18231/j.jdpo.2022.059","DOIUrl":"https://doi.org/10.18231/j.jdpo.2022.059","url":null,"abstract":"Fanconi anemia (FA) is a genetically heterogenous rare autosomal recessive disorder. Mutations in FANCA gene are the most frequent among FA patients accounting for 60-65%. FA is characterised by congenital malformations, progressive bone marrow failure (BMF) and increased risk of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). The risk of developing hematological abnormalities in FA patients is around 98% by 40 years of age. The risk of clonal cytogenetic abnormalities during BMF is around 67% by 30 years of age and risk of developing MDS or AML is 52% by 40 years of age. The frequent chromosomal abnormalities are 1q+, monosomy 7 and gains of 3q. Partial duplications/triplications of chromosome 1q are known to represent a nonrandom chromosomal anomaly in myeloid disorders.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132798946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-15DOI: 10.18231/j.jdpo.2022.061
Sameer Kadam, Hoogar MB, A. Valand, Vaishali Bhonsale, Kirti Pardesi, Nakul Y. Sampat
: Actinomycosis of the oral cavity is not common, though actinomyces species often occur as normal commensals in the oral cavity. They gain entry into deep tissue to cause infection and consequent tissue damage whenever there is damage to the oral mucosa by injury or infection or neoplastic process. The case being discussed here is of a male, aged 62 years, who presented with an ulcero-proliferative lesion over left buccal mucosa. A punch biopsy was carried out on the lesion. Histopathology laboratory received three gray-white tissue pieces. Histological examination of the tissue pieces revealed features of moderately to poorly differentiated squamous cell carcinoma. Few colonies of radiating filamentous structures reminiscent of colonies of actinomyces species were noted. The sections were further stained with relevant stains for filamentous bacteria such as Periodic Acid Schiff (PAS) stain which confirmed the colonies of Actinomyces spp. The case being submitted here is an unique and relatively rare finding of concomitant squamous cell carcinoma and oral actinomycosis with only few cases being reported in publish English medical literature.
{"title":"Concomitant squamous cell carcinoma and actinomycosis—An unique and rare occurrence","authors":"Sameer Kadam, Hoogar MB, A. Valand, Vaishali Bhonsale, Kirti Pardesi, Nakul Y. Sampat","doi":"10.18231/j.jdpo.2022.061","DOIUrl":"https://doi.org/10.18231/j.jdpo.2022.061","url":null,"abstract":": Actinomycosis of the oral cavity is not common, though actinomyces species often occur as normal commensals in the oral cavity. They gain entry into deep tissue to cause infection and consequent tissue damage whenever there is damage to the oral mucosa by injury or infection or neoplastic process. The case being discussed here is of a male, aged 62 years, who presented with an ulcero-proliferative lesion over left buccal mucosa. A punch biopsy was carried out on the lesion. Histopathology laboratory received three gray-white tissue pieces. Histological examination of the tissue pieces revealed features of moderately to poorly differentiated squamous cell carcinoma. Few colonies of radiating filamentous structures reminiscent of colonies of actinomyces species were noted. The sections were further stained with relevant stains for filamentous bacteria such as Periodic Acid Schiff (PAS) stain which confirmed the colonies of Actinomyces spp. The case being submitted here is an unique and relatively rare finding of concomitant squamous cell carcinoma and oral actinomycosis with only few cases being reported in publish English medical literature.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127495118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-15DOI: 10.18231/j.jdpo.2022.062
Vallalkani KN, Sumithra A, H. Volga
Granulomatous gastritis (GG) is a subtype of chronic gastritis which may be infectious, non-infectious, or idiopathic in nature. For treating clinicians, granulomatous gastritis has always been a diagnostic challenge because of the same clinical and endoscopic features between Crohn’s disease and tuberculosis. A diagnosis can be reached only by the combination of histopathological examination with clinical and laboratory investigations. Several studies showed that granulomas are more common in the antrum and are generally located superficially within the gastric pit where the gastric bacteria H.pylori are seen, which can cause damage. We are reporting two rare cases of granulomatous gastritis associated with H.pylori in a 40-year-old male and a 43-year-old female with a negative family history of tuberculosis.
{"title":"An unusual visitant in gastric biopsy- A report of two rare cases","authors":"Vallalkani KN, Sumithra A, H. Volga","doi":"10.18231/j.jdpo.2022.062","DOIUrl":"https://doi.org/10.18231/j.jdpo.2022.062","url":null,"abstract":"Granulomatous gastritis (GG) is a subtype of chronic gastritis which may be infectious, non-infectious, or idiopathic in nature. For treating clinicians, granulomatous gastritis has always been a diagnostic challenge because of the same clinical and endoscopic features between Crohn’s disease and tuberculosis. A diagnosis can be reached only by the combination of histopathological examination with clinical and laboratory investigations. Several studies showed that granulomas are more common in the antrum and are generally located superficially within the gastric pit where the gastric bacteria H.pylori are seen, which can cause damage. We are reporting two rare cases of granulomatous gastritis associated with H.pylori in a 40-year-old male and a 43-year-old female with a negative family history of tuberculosis.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124260056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-15DOI: 10.18231/j.jdpo.2022.064
K. Akhtar, Saman Usmani, Fatma Lubna, Sarah Irfan
Chondrosarcoma is cartilage forming neoplasm which mostly occurs in pelvis, femur and humerous. Chondrosarcoma is rare in the foot and the involvement of phalanges is extremely rare. It is a malignant neoplasm which mimics various epiphysial tumors clinically and radiologically, so histopathology is the gold standard for confirming the diagnosis. We report an unusual case of Grade II Chondrosarcoma in a 60 years old male, who complained of swelling and pain in left great toe for the past two years, which clinically mimicked Osteoclastoma. Imprint smear from swelling in the left great toe showed scattered mononucleated to binucleated oval to plump to polygonal cells with coarse chromatin and moderate eosinophilic cytoplasm in a chondromyxoid background suggestive of malignancy with differentials of Osteosarcoma and Chondrosarcoma. Histomorphology with immunohistochemistry led to the confirmation of diagnosis of this tumor at a rare site.
{"title":"Chondrosarcoma of the great toe clinically mimicking osteoclastoma-An unusual presentation","authors":"K. Akhtar, Saman Usmani, Fatma Lubna, Sarah Irfan","doi":"10.18231/j.jdpo.2022.064","DOIUrl":"https://doi.org/10.18231/j.jdpo.2022.064","url":null,"abstract":"Chondrosarcoma is cartilage forming neoplasm which mostly occurs in pelvis, femur and humerous. Chondrosarcoma is rare in the foot and the involvement of phalanges is extremely rare. It is a malignant neoplasm which mimics various epiphysial tumors clinically and radiologically, so histopathology is the gold standard for confirming the diagnosis. We report an unusual case of Grade II Chondrosarcoma in a 60 years old male, who complained of swelling and pain in left great toe for the past two years, which clinically mimicked Osteoclastoma. Imprint smear from swelling in the left great toe showed scattered mononucleated to binucleated oval to plump to polygonal cells with coarse chromatin and moderate eosinophilic cytoplasm in a chondromyxoid background suggestive of malignancy with differentials of Osteosarcoma and Chondrosarcoma. Histomorphology with immunohistochemistry led to the confirmation of diagnosis of this tumor at a rare site.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127351809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-15DOI: 10.18231/j.jdpo.2022.054
S. Raj, Shristi Soni, D. Aden, Alka Yadav, Sameeksha Raj
Breast cancer is the most common malignancy in women, accounting for 14 % of all cancers in India; it accounts for < 1% of all cancer cases in men. Breast cancer is the leading cause of death worldwide. The study aims to assess the expression of p53 and Survivin in Fibroadenoma and Invasive carcinoma of no special type and its prognostic importance.A total number of 75 cases are included in the study, out of which 34 are reported by two histopathologists as invasive carcinoma NST (ductal) and 41 reported as Fibroadenoma. All the cases included in the study are females. Immunohistochemistry for p53 and Survivin performed in both the groups with positive and negative controls. Cytoplasmic or nuclear IHC expression for Survivin is considered to be positive. Whereas, nuclear positivity is considered for p53. A semi quantitative scoring system performed consisting of intensity and % of positive cells. The expression of Survivin and p53 is found to be high in IDC, 79% and 85% respectively. The correlation is found to be significant (p value = 0.002, Spearman Rho correlation). However, the expression of Survivin is seen in one third of all the cases of Fibroadenoma (37.5%) and p53 expression is expectedly low, seen in 12% cases. Over expression of Survivin in IDC patients compared to benign cases is found to be correlated with p53 expression. Though Survivin is likely to contribute to apoptosis resistance, its expression is found to confer resistance to chemotherapy and radiotherapy in IDC. Henceforth, Survivin over expression along with p53 in invasive breast carcinoma defining overall poor prognosis and low survival rates.
{"title":"Survivin and p53 expression in benign and malignant lesions of breast","authors":"S. Raj, Shristi Soni, D. Aden, Alka Yadav, Sameeksha Raj","doi":"10.18231/j.jdpo.2022.054","DOIUrl":"https://doi.org/10.18231/j.jdpo.2022.054","url":null,"abstract":"Breast cancer is the most common malignancy in women, accounting for 14 % of all cancers in India; it accounts for < 1% of all cancer cases in men. Breast cancer is the leading cause of death worldwide. The study aims to assess the expression of p53 and Survivin in Fibroadenoma and Invasive carcinoma of no special type and its prognostic importance.A total number of 75 cases are included in the study, out of which 34 are reported by two histopathologists as invasive carcinoma NST (ductal) and 41 reported as Fibroadenoma. All the cases included in the study are females. Immunohistochemistry for p53 and Survivin performed in both the groups with positive and negative controls. Cytoplasmic or nuclear IHC expression for Survivin is considered to be positive. Whereas, nuclear positivity is considered for p53. A semi quantitative scoring system performed consisting of intensity and % of positive cells. The expression of Survivin and p53 is found to be high in IDC, 79% and 85% respectively. The correlation is found to be significant (p value = 0.002, Spearman Rho correlation). However, the expression of Survivin is seen in one third of all the cases of Fibroadenoma (37.5%) and p53 expression is expectedly low, seen in 12% cases. Over expression of Survivin in IDC patients compared to benign cases is found to be correlated with p53 expression. Though Survivin is likely to contribute to apoptosis resistance, its expression is found to confer resistance to chemotherapy and radiotherapy in IDC. Henceforth, Survivin over expression along with p53 in invasive breast carcinoma defining overall poor prognosis and low survival rates.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123485587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-15DOI: 10.18231/j.jdpo.2022.055
S. Khan, Y. Momin, A. Gosavi, A. Waje
The human appendix is a supposedly funtionless organ, but can cause morbidity and mortality because it is likely to be infected. Acute Appendicitis being the most common surgical emergency. Appendicectomy specimens from suspected acute appendicitis often appear macroscopically normal but histological analysis reveal a more sinister underlying pathology.A three year study was performed to determine the incidence of various non-neoplastic and neoplastic lesions of appendix. To study the histopathology of various lesions of appendix.It is a retrospective study for a period of three years at Tertiary care hospital. The histopathological reports and clinical details were collected and slides were reviewed and evaluated. Special stains were used wherever required.The study included 1092 cases of lesions of appendix. The commonest lesion was chronic non-specific appendicitis (48.27%) followed by acute appendicitis with (47.80%). Other non neoplastic lesions found were fibrous obliteration of appendix (2.10%), chronic appendicitis with Enterobius vermicularis infestation (0.83), tuberculosis (0.18), xanthogranulomatous appendicitis (0.09%) and amoebic appendicitis (0.09%). Neoplastic lesions seen were low grade mucinous neoplasm (0.18) and serrated adenoma (0.09). Chronic non-specific appendicitis is the commonest appendiceal lesion. The various lesions of appendix clinically present as acute or chronic appendicitis but histology reveals the true nature of the lesion and hence remains the gold standard method.
{"title":"Histopathological study of lesions of appendix","authors":"S. Khan, Y. Momin, A. Gosavi, A. Waje","doi":"10.18231/j.jdpo.2022.055","DOIUrl":"https://doi.org/10.18231/j.jdpo.2022.055","url":null,"abstract":"The human appendix is a supposedly funtionless organ, but can cause morbidity and mortality because it is likely to be infected. Acute Appendicitis being the most common surgical emergency. Appendicectomy specimens from suspected acute appendicitis often appear macroscopically normal but histological analysis reveal a more sinister underlying pathology.A three year study was performed to determine the incidence of various non-neoplastic and neoplastic lesions of appendix. To study the histopathology of various lesions of appendix.It is a retrospective study for a period of three years at Tertiary care hospital. The histopathological reports and clinical details were collected and slides were reviewed and evaluated. Special stains were used wherever required.The study included 1092 cases of lesions of appendix. The commonest lesion was chronic non-specific appendicitis (48.27%) followed by acute appendicitis with (47.80%). Other non neoplastic lesions found were fibrous obliteration of appendix (2.10%), chronic appendicitis with Enterobius vermicularis infestation (0.83), tuberculosis (0.18), xanthogranulomatous appendicitis (0.09%) and amoebic appendicitis (0.09%). Neoplastic lesions seen were low grade mucinous neoplasm (0.18) and serrated adenoma (0.09). Chronic non-specific appendicitis is the commonest appendiceal lesion. The various lesions of appendix clinically present as acute or chronic appendicitis but histology reveals the true nature of the lesion and hence remains the gold standard method.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131981887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-15DOI: 10.18231/j.jdpo.2022.057
Geethamala K, M. Jadhav, Sneha K, Nirmala BL, R. Haravi, Shirish Patil
Sinonasal and pharyngeal mass lesion of Extraskeletal Ewing sarcomas (EEWSs) are extremely rare. Herein we present a case of EEWSs of ethmoid sinus extending into nasal and pharyngeal spaces mimicking as angiofibroma clinically. Histopathological examination in conjunction with immunohistochemistry puzzled out the diagnostic dilemma.
{"title":"Sino-nasal and pharyngeal mass- Immunohistochemistry cuts the gordian knot","authors":"Geethamala K, M. Jadhav, Sneha K, Nirmala BL, R. Haravi, Shirish Patil","doi":"10.18231/j.jdpo.2022.057","DOIUrl":"https://doi.org/10.18231/j.jdpo.2022.057","url":null,"abstract":"Sinonasal and pharyngeal mass lesion of Extraskeletal Ewing sarcomas (EEWSs) are extremely rare. Herein we present a case of EEWSs of ethmoid sinus extending into nasal and pharyngeal spaces mimicking as angiofibroma clinically. Histopathological examination in conjunction with immunohistochemistry puzzled out the diagnostic dilemma.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131911134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-15DOI: 10.18231/j.jdpo.2022.065
S. Sachdev, Kavita Wadde, Asha Chowdhar, Prachi Mathe
Odontogenic myxoma (OM) is a rare benign odontogenic tumor characterized by stellate and spindle-shaped cells dispersed in an abundant myxoid extracellular matrix. The bony invasion by the tumor imparts a characteristic ‘soap bubble’, ‘honeycomb’, or ‘tennis racquet’ radiographic appearance to the lesion. The decision of adopting a conservative or radical approach also depends on various factors such as location, size, and duration of the lesion, and age, gender, and expectations of the patient. Therefore, adequate treatment planning is crucial for the management of cases of OM and varies on an individual basis. The present case report described the management of a case of unusually large OM occurring in a 31-year-old Indian female in the mandibular anterior region crossing the midline.
{"title":"Characteristic yet unusual presentation of an odontogenic myxoma in the anterior mandible","authors":"S. Sachdev, Kavita Wadde, Asha Chowdhar, Prachi Mathe","doi":"10.18231/j.jdpo.2022.065","DOIUrl":"https://doi.org/10.18231/j.jdpo.2022.065","url":null,"abstract":"Odontogenic myxoma (OM) is a rare benign odontogenic tumor characterized by stellate and spindle-shaped cells dispersed in an abundant myxoid extracellular matrix. The bony invasion by the tumor imparts a characteristic ‘soap bubble’, ‘honeycomb’, or ‘tennis racquet’ radiographic appearance to the lesion. The decision of adopting a conservative or radical approach also depends on various factors such as location, size, and duration of the lesion, and age, gender, and expectations of the patient. Therefore, adequate treatment planning is crucial for the management of cases of OM and varies on an individual basis. The present case report described the management of a case of unusually large OM occurring in a 31-year-old Indian female in the mandibular anterior region crossing the midline.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131480821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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