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Ultrasonographic view of fluid bronchogram secondary to endobronchial obstruction: A case report 继发于支气管内梗阻的支气管积液声像图1例。
Q3 Medicine Pub Date : 2025-01-09 DOI: 10.1002/ajum.12418
Yash Kedia, Nitesh Gupta, Rohit Kumar

Background

Ultrasound has become an important aspect of emergency medicine due to its wide availability and portability for bedside investigations. Understanding some important ultrasound findings can aid in diagnosis and management.

Key findings

We present a case of a 65-year-old smoker who presented with shortness of breath and hemoptysis and was in respiratory failure upon arrival in the emergency department. Bedside ultrasound demonstrated a fluid bronchogram, aiding the diagnosis of lung collapse secondary to endobronchial obstruction.

Discussion

Fluid bronchograms are seen on CT chest and ultrasonography as linear images corresponding to dilated bronchus, filled with mucus, distal to an endobronchial obstruction. They are characterised by anechoic, tubular structures, suggestive of fluid filled bronchi, over the hypoechogenic pulmonary parenchyma, and can be differentiated from blood vessels by the lack of Doppler signal. Ultrasonographic image of fluid bronchogram is very unique and can help to detect collapse secondary to endobronchial obstruction using point-of-care ultrasonography in emergency.

背景:由于超声检查的广泛性和便携性,超声检查已成为急诊医学的一个重要方面。了解一些重要的超声检查结果有助于诊断和治疗:我们介绍了一例 65 岁吸烟者的病例,该患者因呼吸急促和咯血前来就诊,到达急诊科时已出现呼吸衰竭。床旁超声检查显示支气管积液,有助于诊断支气管内膜阻塞导致的肺塌陷:讨论:胸部 CT 和超声波检查发现的液性支气管图是支气管内膜阻塞远端扩张、充满粘液的线性图像。其特点是在低回声的肺实质上出现无回声的管状结构,提示支气管内充满液体,可通过缺乏多普勒信号与血管相鉴别。液性支气管的超声图像非常独特,有助于在急诊中利用护理点超声检查发现继发于支气管内阻塞的塌陷。
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引用次数: 0
Application of the 2023 World Heart Federation guidelines for the echocardiographic diagnosis of rheumatic heart disease 2023年世界心脏联合会指南在风湿性心脏病超声心动图诊断中的应用
Q3 Medicine Pub Date : 2025-01-09 DOI: 10.1002/ajum.12421
Jacqueline Williamson, Amelia McLeod, James Marangou, Bo Remenyi, Peter Morris, Gillian Whalley

Rheumatic heart disease remains prevalent in some regions of Australia and New Zealand. Echocardiography is the gold standard for detection and diagnosis using the 2023 World Heart Federation guidelines. The guidelines describe specific features of mitral and aortic valve morphology and define pathological regurgitation associated with RHD. The aim of this education piece was to assist cardiac sonographers and reporting specialists in the accurate detection, diagnosis, and classification of RHD findings. We present the echocardiographic features of RHD as defined by the 2023 WHF guidelines, including a poster summarising the individual criteria for diagnosis.

风湿性心脏病在澳大利亚和新西兰的一些地区仍然很普遍。超声心动图是使用2023年世界心脏联合会指南进行检测和诊断的金标准。该指南描述了二尖瓣和主动脉瓣形态的具体特征,并定义了与RHD相关的病理性反流。这篇教育文章的目的是帮助心脏超声医师和报告专家准确检测、诊断和分类RHD的发现。我们介绍了2023年WHF指南中定义的RHD的超声心动图特征,包括一张总结诊断标准的海报。
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引用次数: 0
Anatomy – The foundation of ultrasound imaging 解剖学-超声成像的基础。
Q3 Medicine Pub Date : 2024-12-26 DOI: 10.1002/ajum.12416
Gillian Whalley
<p>Ultrasound is <i>the</i> most accessible, and the most utilised, of all medical imaging. Miniaturisation has reduced the cost and the portability such that anatomical imaging is now available in places we would never have ventured in the past. Today, it is possible to image a growing fetus in the middle of desert with no wired electricity; or to image the chest of a sailor on a yacht in the middle of the ocean to identify whether they have a ruptured aortic aneurysm; or to determine the extent of internal bleeding of an injured soldier in the middle of a warzone; or to identify a child in a remote location that is suffering from rheumatic heart disease and needs life-preserving penicillin treatment. Diagnostic ultrasound should be available to everyone, and everywhere, but the image quality may not be the same, and we may be restricted to simple black and white anatomy.</p><p>Since my career with ultrasound began, we have moved from being able to image the anatomy in two dimensions with limited functional assessment, to three-dimensional moving images with blood flow measurement and tissue motion detection, to name but a few innovations. We use ultrasound beyond diagnosis, to predict prognosis and to plan treatment strategies, but the new wave of handheld transducers has brought us back to the beginning and reminds me that anatomy is key. The so much clinical information can be obtained from simple grey scale anatomical pictures. Anatomy remains the foundation of ultrasound imaging.</p><p>In this issue of AJUM, we are reminded that underlying anatomical knowledge is key to important clinical decisions. Ward <i>et al</i>.<span><sup>1</sup></span> use ultrasound to document the migration of the placental cord insertion during pregnancy and suggest that this should be routinely reported on antenatal ultrasound examinations.</p><p>Fenech <i>et al</i>.<span><sup>2</sup></span> present a detailed review article about anatomy and ultrasound appearances of femoral and saphenous veins, and their branches, and advocate for users to become familiar with the normal appearances in order that we may accurately identify abnormalities. The imaging of nerves is increasingly being utilised as a tool for nerve blockade. Ultrasound anatomical imaging is frequently used to assist procedures. and Zanfini <i>et al</i>.<span><sup>3</sup></span> present a series of over 500 intrathecal injections where ultrasound was used to help identity the injection site. Although intravenous access can be done without ultrasound imaging, would you want to ignore the benefits of improved precision with anatomical image guidance?</p><p>I, like many student sonographers, learned and refined my anatomical knowledge while looking at ultrasound images. I watch as newly qualified doctors remembering their anatomy as they look at an ultrasound screen. And increasingly, ultrasound is being applied in medical schools to supplement medical students' anatomy learning. Anatomy is the heart of
超声是所有医学成像中最容易获得、使用最多的。小型化降低了成本和便携性,使得解剖成像现在可以在我们过去从未冒险过的地方进行。今天,我们可以想象一个正在成长的胎儿在没有电线的沙漠中;或者在海洋中央的游艇上给水手的胸部拍照,以确定他们是否有破裂的主动脉瘤;或者在战区中确定受伤士兵的内出血程度;或者在偏远地区发现一个患有风湿性心脏病、需要青霉素治疗的孩子。诊断超声应该对每个人都可用,在任何地方,但图像质量可能不一样,我们可能仅限于简单的黑白解剖。自从我的超声职业生涯开始以来,我们已经从能够在有限的功能评估的二维解剖成像,发展到具有血流测量和组织运动检测的三维运动图像,仅举几例创新。我们在诊断之外使用超声波来预测预后和制定治疗策略,但新一波的手持换能器把我们带回到开始,提醒我解剖是关键。从简单的灰度解剖图像中可以获得如此多的临床信息。解剖学仍然是超声成像的基础。在本期《美国医学会杂志》中,我们被提醒,基础解剖学知识是重要临床决策的关键。Ward等人1使用超声记录妊娠期间胎盘脐带插入的移动,并建议这应在产前超声检查中常规报告。Fenech et al.2发表了一篇详细的关于股静脉和隐静脉及其分支的解剖和超声表现的综述文章,并提倡用户熟悉正常的外观,以便我们能够准确地识别异常。神经成像越来越多地被用作神经阻断的工具。超声解剖成像常用于辅助手术。和Zanfini等人3提出了一系列超过500次的鞘内注射,其中超声用于帮助识别注射部位。虽然静脉注射可以在没有超声成像的情况下进行,但你会想忽视解剖图像引导下提高精度的好处吗?我和许多学生超声医师一样,在看超声图像的过程中学习和完善了我的解剖学知识。我看着刚获得资格的医生在看超声波屏幕时记住他们的解剖结构。超声越来越多地应用于医学院,以补充医学生的解剖学学习。解剖是ASUM成员和AJUM读者每天使用超声的核心。
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引用次数: 0
Identifying enablers and barriers to teleultrasound use for remote settings: A scoping review 确定远程超声在偏远地区使用的促进因素和障碍:范围审查。
Q3 Medicine Pub Date : 2024-12-13 DOI: 10.1002/ajum.12415
Aubree Anderson, Rebecca G Theophanous

Introduction/Purpose

Teleultrasound connects expert point-of-care ultrasound (POCUS) users with remote community and rural sites. Evolving technologies including handheld devices, upgraded image quality, and the ability to transmit over low bandwidth connections increase POCUS education, accessibility, and clinical integration. Potential teleultrasound venues include low-resource settings, prehospital care, and austere environments (high altitudes, microgravity, conflict zones, etc.). This scoping review assesses current teleultrasound uses and identifies implementation enablers and barriers.

Methods

Using the PRISMA-ScR checklist, PubMed, Embase, and Cochrane were searched on 16 August 2024 for teleultrasound studies. Two reviewers independently screened results and abstracted data using a data collection table. 165 articles met the following inclusion criteria: research studies describing teleultrasound, involving humans, including healthcare workers, with remote point-of-care or medical ultrasound use, in any setting, and in English.

Results

Teleultrasound studies were reported in most specialties and across all continents. Most were prospective (100 studies), review articles (27), or case studies (14). Study quality was variable, with 28 high quality, 77 moderate, 54 low, and 6 very low (GRADE assessment tool). Common themes that emerged include (1) type of image transmission method utilised, (2) remote provider training and curriculum development, (3) feedback methods between expert and novice users, (4) technologies and devices used, and (5) enablers and barriers to guide future teleultrasound implementation and training strategies.

Conclusion

Overall, the teleultrasound literature is heterogeneous in setting, design, and quality outcomes. As teleultrasound technology evolves and the use expands, future studies should standardise protocols and ensure image quality fidelity to optimise remote patient care.

介绍/用途:Teleultrasound将专家护理点超声(POCUS)用户与偏远社区和农村站点连接起来。包括手持设备、升级的图像质量和通过低带宽连接传输的能力在内的不断发展的技术增加了POCUS教育、可访问性和临床集成。潜在的远程超声场所包括低资源环境、院前护理和恶劣环境(高海拔、微重力、冲突地区等)。本范围审查评估了目前远程超声的使用,并确定了实施的推动因素和障碍。方法:使用PRISMA-ScR检查表,检索PubMed, Embase和Cochrane于2024年8月16日进行的远程超声研究。两名审稿人独立筛选结果并使用数据收集表提取数据。165篇文章符合以下纳入标准:描述远程超声的研究,涉及人类,包括卫生保健工作者,在任何环境下使用远程护理点或医疗超声,并以英语进行。结果:远程超声研究报告在大多数专业和所有大陆。大多数是前瞻性研究(100项研究)、综述性文章(27篇)或案例研究(14篇)。研究质量是可变的,28个高质量,77个中等质量,54个低质量,6个非常低质量(GRADE评估工具)。出现的共同主题包括(1)使用的图像传输方法类型,(2)远程提供者培训和课程开发,(3)专家和新手用户之间的反馈方法,(4)使用的技术和设备,以及(5)指导未来远程超声实施和培训策略的促成因素和障碍。结论:总体而言,远程超声文献在设置、设计和质量结果方面存在差异。随着远程超声技术的发展和应用的扩大,未来的研究应该标准化协议,确保图像质量的保真度,以优化远程患者护理。
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引用次数: 0
Ultrasound evaluation of peripheral intravenous catheter thrombus formation associated with intravenous flucloxacillin administration: A prospective observational pilot study 超声评价与氟氯西林静脉注射相关的外周静脉导管血栓形成:一项前瞻性观察性先导研究。
Q3 Medicine Pub Date : 2024-11-27 DOI: 10.1002/ajum.12414
Andrew C. Bulmer, Rachael Nightingale, Wenu Hewage, Gerben Keijzers, Peter J. Snelling

Purpose

The purpose of this study was to sonographically evaluate whether intravenous (IV) flucloxacillin administration was associated with an increased risk of peripheral intravenous catheter (PIVC) thrombus formation.

Methods

This observational study included participants enrolled as a convenience sample from a larger prospective study of patients with cellulitis receiving IV antibiotics in the emergency department. Point-of-care ultrasound was used to evaluate the PIVCs for thrombus formation after insertion and at specified timepoints after IV administration of antibiotic or saline solution through to discharge. The primary endpoint included the presence and length of the thrombus in proximity of the catheter tip.

Results

Between May 2021 and June 2022, 25 participants were enrolled and received either IV flucloxacillin (n = 10), other IV antibiotics (n = 8) or no IV antibiotics (control; n = 7). PIVC thrombus formation was sonographically detected in 100%, 67% and 17% of patients in flucloxacillin, other and control groups at 6–12 h (flucloxacillin vs. control; P = 0.015), with a mean length of 17.4 ± 8.1 (flucloxacillin vs. control; P = 0.46), 15.5 ± 13.4 (other vs. control; P = 0.73) and 7.3 ± 17.9 mm (control), respectively. Thrombus formation increased significantly in the flucloxacillin group over time (0–>12 h; P = 0.03) but did not increase in the other or control groups.

Discussion

The administration of IV flucloxacillin appears to promote the formation of a PIVC thrombus visible on ultrasound, but the clinical implications are uncertain. Although the vast majority appear to be asymptomatic, they have the potential to become a precursor to thrombophlebitis and lead to early PIVC failure.

Conclusions

It was feasible to identify and measure PIVC thrombus sonographically. Ultrasound showed that IV flucloxacillin administration appeared to be associated with more frequent formation of PIVC thrombus, with these increasing in length over time. Further research is required to confirm these findings in larger studies and to identify any clinical implications of the findings.

目的:本研究旨在通过声像图评估静脉注射氟氯西林是否会增加外周静脉导管(PIVC)血栓形成的风险:这项观察性研究是从一项针对在急诊科接受静脉注射抗生素治疗的蜂窝组织炎患者的大型前瞻性研究中抽取的方便样本。在插入PIVC后,以及在静脉注射抗生素或生理盐水后至出院的特定时间点,采用床旁超声评估PIVC是否有血栓形成。主要终点包括导管尖端附近是否存在血栓以及血栓的长度:2021年5月至2022年6月期间,25名参与者接受了氟氯西林静脉注射(10人)、其他抗生素静脉注射(8人)或无抗生素静脉注射(对照组;7人)。声像图显示,氟氯西林组、其他组和对照组分别有100%、67%和17%的患者在6-12小时内发现PIVC血栓形成(氟氯西林组与对照组相比;P = 0.015),平均长度分别为17.4 ± 8.1(氟氯西林组与对照组相比;P = 0.46)、15.5 ± 13.4(其他组与对照组相比;P = 0.73)和7.3 ± 17.9毫米(对照组)。随着时间的推移,氟氯西林组的血栓形成明显增加(0->12 h;P = 0.03),但其他组和对照组的血栓形成没有增加:讨论:静脉注射氟氯西林似乎能促进超声波可见的PIVC血栓形成,但其临床意义尚不确定。尽管绝大多数血栓似乎没有症状,但它们有可能成为血栓性静脉炎的前兆,并导致 PIVC 早期失效:结论:用超声波识别和测量PIVC血栓是可行的。超声波显示,静脉注射氟氯西林似乎与PIVC血栓的频繁形成有关,而且这些血栓的长度会随着时间的推移而增加。要在更大规模的研究中证实这些发现,并确定这些发现的临床意义,还需要进一步的研究。
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引用次数: 0
Systematic review of musculoskeletal ultrasound learning methodologies 肌肉骨骼超声学习方法的系统综述。
Q3 Medicine Pub Date : 2024-10-21 DOI: 10.1002/ajum.12413
Amber J. Vogt, Robert Samuel Mayer

Introduction/Purpose

As the frequency and morbidity of musculoskeletal (MSK) disorders increase, the use of MSK ultrasound has become an important diagnostic and procedural tool. This has amplified the importance of quality MSK ultrasound training for medical professionals. This systematic review evaluated and compared peer-reviewed journal articles on learning methodologies for MSK ultrasound training.

Methods

Thirty-three articles met inclusion and exclusion criteria and were evaluated.

Results

Results showed a lack of randomised studies that compared learning methodologies.

Conclusion

There was wide variability of methodology used based on educational and institutional needs. Further randomised control trials need to be conducted to ascertain best educational practices.

简介/目的:随着肌肉骨骼(MSK)疾病的频率和发病率的增加,MSK超声的使用已成为重要的诊断和手术工具。这加强了对医疗专业人员进行高质量MSK超声培训的重要性。本系统综述评估和比较同行评议的关于MSK超声训练学习方法的期刊文章。方法:对33篇符合纳入和排除标准的文献进行评价。结果:结果显示缺乏比较学习方法的随机研究。结论:根据教育和机构的需要,使用的方法有很大的可变性。需要进行进一步的随机对照试验来确定最佳的教育实践。
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引用次数: 0
Ultrasound measurement of perirenal adipose tissue indicates cardiovascular disease, but standardisation is needed: A systematic review 超声测量肾周脂肪组织提示心血管疾病,但需要标准化:一项系统综述。
Q3 Medicine Pub Date : 2024-10-20 DOI: 10.1002/ajum.12407
Victoria J. A. Baumann, Richard Banati, Jillian L. Clarke

Introduction

In both highly industrialised and developing countries, obesity is reaching epidemic proportions and increasingly becoming a critical indicator of general morbidity, cardiovascular disease (CVD) and renal dysfunction. A promising trend in detection and management of obesity is the measurement of perirenal adipose tissue (PRAT), increasingly recognised as a metabolically active endocrine organ in itself. Its measurement by ultrasound is used increasingly to indicate visceral obesity and its clinical management. This review synthesises current techniques for measuring PRAT and its potential use as an indicator of CVD.

Methods

We included clinical studies published between 2010 and 2023, investigating the current practice and use of specific ultrasonographic techniques and assessed the reliability and accuracy of included papers. The risk of bias was assessed using the Downs and Black Checklist, and the methodological quality examined using the Grade of Recommendations, Assessments, Development and Evaluation.

Results

It found, PRAT measures are predictive of CVD risk factors and the accuracy of ultrasound is comparable to CT and MRI, but there is no consistency in ultrasound technique. The lack of any randomised control trials and the use of 20 different non-standardised ultrasound techniques across the 21 studies resulted in inconsistent and imprecise clinical observations and interpretations, which decreased the overall quality of the studies.

Conclusion

This review found the inclusion of ultrasound measures in routine abdominal imaging potentially invaluable but demonstrates the need for standardisation of the perirenal fat ultrasound measuring technique to improve reproducibility and reliability.

导言:在高度发达的工业化国家和发展中国家,肥胖症都已达到流行病的程度,并日益成为全身发病率、心血管疾病 (CVD) 和肾功能障碍的重要指标。在肥胖症的检测和管理方面,一个很有前景的趋势是对肾周脂肪组织(PRAT)进行测量,因为人们越来越认识到,肾周脂肪组织本身就是一个代谢活跃的内分泌器官。通过超声波对其进行测量,越来越多地用于显示内脏肥胖及其临床管理。本综述总结了目前测量 PRAT 的技术及其作为心血管疾病指标的潜在用途:我们纳入了 2010 年至 2023 年间发表的临床研究,这些研究调查了特定超声波技术的当前实践和使用情况,并评估了纳入论文的可靠性和准确性。采用唐斯和布莱克检查表评估偏倚风险,采用推荐、评估、发展和评价等级检查方法学质量:研究发现,PRAT 测量可预测心血管疾病的风险因素,超声波的准确性与 CT 和 MRI 相当,但超声波技术并不一致。由于缺乏随机对照试验,21 项研究中使用了 20 种不同的非标准化超声技术,导致临床观察和解释不一致、不精确,从而降低了研究的整体质量:本综述认为,将超声测量纳入常规腹部成像具有潜在的价值,但需要对肾周脂肪超声测量技术进行标准化,以提高可重复性和可靠性。
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引用次数: 0
Ultrasound transducer disinfection for percutaneous procedures: A review of the evidence supporting guideline recommendations 经皮手术用超声换能器消毒:支持指南建议的证据综述
Q3 Medicine Pub Date : 2024-09-30 DOI: 10.1002/ajum.12408
Nathan Peters, Frances Williamson, Victoria Eley

Introduction/Purpose

There are varying international recommendations regarding the minimum level of disinfection required for ultrasound transducers used in percutaneous procedures. While some guidelines recommend high-level disinfection (HLD), others question the additional benefit this delivers over low-level disinfection (LLD).

Methods

This narrative review identifies current guidelines and evaluates the evidence used to support disinfection recommendations for ultrasound transducers used in percutaneous procedures. Thirteen guidelines were identified using a search encompassing PubMed, Embase, Scopus and Google from 1st January 2013 to 31st January 2024.

Results

No guidelines were supported by high-quality evidence, instead, guidelines relied upon: expert opinion through the application of national standards and infection control principles; consideration of recommendations from other published guidelines; and the incidence of infection from retrospective studies. Guidelines were uniformly supportive of using ultrasound transducer covers and sterile ultrasound gel during ultrasound-guided percutaneous procedures. However, the minimum recommended disinfection level was varied with seven guidelines recommending HLD, four LLD and two not specifying a level. Spaulding's classification was commonly used to support disinfection recommendations, however, the resultant wide variation in classification and subsequent recommendations suggest that its utility in accurately determining the minimum level of disinfection in this specific context is low.

Conclusion

Without high-level evidence, using a risk-based assessment will likely remain fundamental to future guideline recommendations in determining the minimum disinfection level for an ultrasound transducer used in percutaneous procedures. This risk assessment must include the highest level of evidence available in addition to acknowledging the contribution of all steps taken to prevent infection during ultrasound-guided percutaneous procedures.

介绍/目的:关于经皮手术中使用的超声换能器所需的最低消毒水平,国际上有不同的建议。虽然一些指南建议采用高水平消毒(HLD),但也有人质疑这种方法比低水平消毒(LLD)带来的额外好处。方法:这篇叙述性综述确定了目前的指南,并评估了用于支持经皮手术中使用的超声换能器消毒建议的证据。从2013年1月1日至2024年1月31日,通过检索PubMed、Embase、Scopus和谷歌,确定了13份指南。结果:指南没有高质量的证据支持,指南依赖于专家意见,通过应用国家标准和感染控制原则;审议其他已公布的准则的建议;以及回顾性研究中感染的发生率。指南一致支持在超声引导的经皮手术中使用超声换能器盖和无菌超声凝胶。然而,建议的最低消毒水平各不相同,有7项指南建议使用HLD, 4项建议使用LLD,还有2项没有指定消毒水平。斯波尔丁的分类通常用于支持消毒建议,然而,由此产生的分类和随后的建议的广泛差异表明,在这种特定情况下,它在准确确定最低消毒水平方面的效用很低。结论:在没有高水平证据的情况下,在确定经皮手术中使用的超声换能器的最低消毒水平时,使用基于风险的评估可能仍然是未来指南建议的基础。这种风险评估必须包括现有的最高水平的证据,除了承认在超声引导的经皮手术中预防感染所采取的所有步骤的贡献。
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引用次数: 0
Klebsiella liver phlegmon mimicking a solid liver tumour 克雷伯氏菌肝痰模拟实体肝肿瘤。
Q3 Medicine Pub Date : 2024-09-30 DOI: 10.1002/ajum.12406
Martin Necas, Jereme Mitchell

Introduction

This case examines the sonographic and clinical challenge of diagnosing a Klebsiella pnumoniae pyogenic liver abscess with systemic metastatic infection.

Case Description

The patient in this case study is an 81-year-old man who presented with intermittent rigors. Following radiological and clinical assessments, a Klebsiella pnumoniae pyogenic liver abscess, with evidence of systemic metastatic infection, was diagnosed. Sonographic features of the liver abscess were atypical for a cystic lesion and instead appeared as a solid mass, raising the possibility of malignancy. Treatment of intravenous ceftriaxone infusions resulted in full resolution of the liver lesion.

Discussion

The discussion criticises the terminology when describing hepatic lesions, which result from a Klebsiella pnumoniae infection. The term hepatic phlegmon is appropriate when a liver lesion caused by bacterial infection demonstrates a solid appearance on radiologic imaging. The term hepatic abscess is appropriate in cases where liver lesions caused by bacterial infection demonstrate a fluid filled core on radiologic imaging. Differentiation of these terms is important when treating the underlying lesion as a phlegmon, in contrast to an abscess, cannot be drained because it contains no pus. The variable sonographic appearances of Klebsiella pnumoniae pyogenic abscesses were also examined. Despite reported sonographic appearances in the literature, none are sufficient to distinguish a pyogenic liver abscess from malignancy without further investigation.

Conclusion

Ultrasound operators should be aware of the variable sonographic appearances of a Klebsiella pnumoniae liver abscess and how these features, combined with non-homogenous terminology, can obfuscate the correct diagnosis.

本病例探讨肺炎克雷伯菌化脓性肝脓肿合并全身转移性感染的超声诊断和临床挑战。病例描述:本病例研究中的患者是一名81岁的男性,表现为间歇性僵硬。经过放射学和临床评估,诊断为肺炎克雷伯菌化脓性肝脓肿,伴有全身转移感染的证据。肝脓肿的超声特征不典型为囊性病变,而是表现为实性肿块,提高了恶性肿瘤的可能性。静脉注射头孢曲松治疗导致肝脏病变完全消退。讨论:讨论批评了描述由肺炎克雷伯菌感染引起的肝脏病变的术语。当由细菌感染引起的肝脏病变在放射影像上表现为实性时,称为肝性痰。当由细菌感染引起的肝脏病变在放射影像上表现为充满液体的核心时,称为肝脓肿。当将潜在病变视为痰时,区分这些术语是很重要的,与脓肿相反,脓肿不能排出,因为它不含脓。同时也检查了肺炎克雷伯菌化脓肿的各种超声表现。尽管有文献报道的超声表现,但没有一个足以区分化脓性肝脓肿和恶性肿瘤而不进一步调查。结论:超声操作人员应了解肺炎克雷伯菌肝脓肿的不同声像图表现,以及这些特征与不同质的术语如何混淆正确诊断。
{"title":"Klebsiella liver phlegmon mimicking a solid liver tumour","authors":"Martin Necas,&nbsp;Jereme Mitchell","doi":"10.1002/ajum.12406","DOIUrl":"10.1002/ajum.12406","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>This case examines the sonographic and clinical challenge of diagnosing a <i>Klebsiella pnumoniae</i> pyogenic liver abscess with systemic metastatic infection.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Description</h3>\u0000 \u0000 <p>The patient in this case study is an 81-year-old man who presented with intermittent rigors. Following radiological and clinical assessments, a <i>Klebsiella pnumoniae</i> pyogenic liver abscess, with evidence of systemic metastatic infection, was diagnosed. Sonographic features of the liver abscess were atypical for a cystic lesion and instead appeared as a solid mass, raising the possibility of malignancy. Treatment of intravenous ceftriaxone infusions resulted in full resolution of the liver lesion.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>The discussion criticises the terminology when describing hepatic lesions, which result from a <i>Klebsiella pnumoniae</i> infection. The term hepatic phlegmon is appropriate when a liver lesion caused by bacterial infection demonstrates a solid appearance on radiologic imaging. The term hepatic abscess is appropriate in cases where liver lesions caused by bacterial infection demonstrate a fluid filled core on radiologic imaging. Differentiation of these terms is important when treating the underlying lesion as a phlegmon, in contrast to an abscess, cannot be drained because it contains no pus. The variable sonographic appearances of <i>Klebsiella pnumoniae</i> pyogenic abscesses were also examined. Despite reported sonographic appearances in the literature, none are sufficient to distinguish a pyogenic liver abscess from malignancy without further investigation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Ultrasound operators should be aware of the variable sonographic appearances of a <i>Klebsiella pnumoniae</i> liver abscess and how these features, combined with non-homogenous terminology, can obfuscate the correct diagnosis.</p>\u0000 </section>\u0000 </div>","PeriodicalId":36517,"journal":{"name":"Australasian Journal of Ultrasound in Medicine","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143053398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of ultrasound imaging on patient management – Let's practice the evidence 超声波成像对患者管理的影响 - 让我们实践证据
Q3 Medicine Pub Date : 2024-09-25 DOI: 10.1002/ajum.12412
Gillian Whalley
<p>As a novice researcher, I worked with a cardiology professor who was driven by clinical evidence. Clinical trials were his bread and butter, and leading guideline writing groups became his passion. The most memorable take-home message for me was this: Before you do any test, a clinician should ask themselves, ‘Will this change management? And if so, how?’ A clinician should know what they will do if the test is positive or negative and be able to articulate that. Sadly, this is not always the case. And whilst it might be ‘nice to know’, the cost of confirmatory tests is certainly not insignificant.</p><p>When I trained in ultrasound, we still called it ‘diagnostic ultrasound’ to differentiate it from therapeutic ultrasound, but this also highlighted the immense and unique diagnostic properties of ultrasound. Increasingly, ultrasound is used to not only diagnose, but also to monitor and screen for conditions, as well as to aid in management and prognosis. While all of these are laudable uses, I still think it is helpful when we can link our imaging directly to change in management.</p><p>In this issue of AJUM, Smith and Mistry<span><sup>1</sup></span> present research documenting the impact of formal echocardiography (echo) on patient management in a small clinical audit of formal echos in their intensive care unit (ICU). Although half of the patients had critical findings found on formal echo, only 25% resulted in management change. Perhaps, the remainder of the critical findings were either already suspected, and therefore being treated; or had been anticipated. Indeed, it is possible that a point of care ultrasound (POCUS) had already given them some clinical cues, and thus, the formal echo was simply confirmatory. In a reasonable number of patients, the formal echo helped make the decision to proceed with palliation and this seems an entirely reasonable reason to do an extra imaging test.</p><p>Also, in the ICU setting, Xin <i>et al</i>.<span><sup>2</sup></span> report on the use of Tissue Doppler Imaging (TDI) of the diaphragm to optimise the timing of weaning from mechanical ventilation in ICU patients. Using TDI to measure the low velocity motion of heart muscle is fundamental to echocardiography, so the extension to the diaphragm seems a logical extension of practice. But a good idea still needs to be tested and shown to aid patient management. Innovation needs to be effective.</p><p>Innovation is a key part of medicine, and finding new applications for imaging is part of that. Lau <i>et al</i>.<span><sup>3</sup></span> applied shear wave elastography to patients in a case–control study comparing patients with COVID-19 with controls and found that patients with recent (<6 months) COVID-19 had increased liver stiffness. They were prompted to do the study after observing elevated liver enzymes in these patients. But as the authors point out, these may be transient changes, and data are needed to see whether these abnormalities are asso
作为一名研究新手,我曾与一位以临床证据为动力的心脏病学教授共事。临床试验是他的面包和黄油,而领导指南编写小组则是他的激情所在。他给我留下的最深刻的启示是这样的:在做任何试验之前,临床医生都应该问自己:'这会改变管理吗?如果会,如何改变?临床医生应该知道,如果检测结果呈阳性或阴性,他们会怎么做,并能清楚地表达出来。遗憾的是,情况并非总是如此。在我接受超声波培训时,我们仍称其为 "诊断性超声波",以区别于治疗性超声波,但这也凸显了超声波巨大而独特的诊断特性。越来越多的超声波不仅用于诊断,还用于监测和筛查疾病,以及辅助管理和预后。在本期的《AJUM》杂志上,Smith 和 Mistry1 介绍了一项研究,该研究记录了正规超声心动图(echo)对重症监护病房(ICU)正规超声检查的影响。虽然半数患者在正式回波检查中发现了危急病症,但只有 25% 的患者改变了治疗方案。也许,其余的重要发现要么是已经被怀疑,因此正在接受治疗;要么是早有预料。事实上,护理点超声检查(POCUS)可能已经给了他们一些临床线索,因此,正式回波检查只是确认而已。在一定数量的患者中,正式回声有助于做出继续姑息治疗的决定,这似乎是进行额外成像检测的一个完全合理的理由。此外,在重症监护病房环境中,Xin 等人2 报告了使用横膈膜组织多普勒成像(TDI)优化重症监护病房患者机械通气断流时机的情况。使用 TDI 测量心肌的低速运动是超声心动图的基础,因此扩展到膈肌似乎是顺理成章的做法。但是,一个好的想法仍然需要经过测试,并证明它能帮助患者进行管理。创新是医学的重要组成部分,而为成像技术寻找新的应用领域也是创新的一部分。刘(Lau)等人3在一项病例对照研究中对COVID-19患者和对照组患者进行了剪切波弹性成像比较,发现近期(6个月)COVID-19患者的肝脏硬度增加。他们是在观察到这些患者肝酶升高后才进行这项研究的。但正如作者所指出的,这些可能只是短暂的变化,还需要数据来确定这些异常是否与持续性肝损伤有关。关于肝脏的超声评估,衰减成像(ATI)是一种相对较新的超声技术,可对衰减进行定量评估,有助于评估肝脂肪变性或脂肪肝。Tan 等人4 介绍了他们对在同一天接受超声检查和肝活检的患者的数据,并得出结论:虽然 ATI 与脂肪变性的组织学分级密切相关,但放射科医生的定性印象实际上是组织学结果的最佳相关性。这是一个 ATI 无助于诊断的例子,同时也引出了一个问题:如果这些患者仍然要做肝活检,那么在超声检查中增加 ATI 真的有意义吗?这个问题的答案就是证据。当我开始超声波之旅的时候,诊断心脏瓣膜疾病的金标准是有创心导管检查。但是,具有前瞻性思维的临床科学家进行的创新研究提供了证据,因此超声心动图现在已成为量化心脏瓣膜疾病的黄金标准。虽然我认为我们为超声波找到了新的临床应用并使用了正在开发的新技术,但正如这些论文所做的那样,我们必须衡量这些技术的临床效果,这一点非常重要。如果新技术不能增加临床价值,我们就必须放弃,事实上,有些技术可能会造成伤害。成像技术为患者带来的额外临床益处应该是显而易见的,成像技术不应该被常规用作另一种确诊或安慰性检查。当然,在某些情况下,后者在临床上是完全合适的。探索新兴超声技术的临床应用具有重要作用;然而,正如这些论文所显示的,研究应包括这些技术作为独立检查的临床有效性,而不仅仅是确认性的保证。
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引用次数: 0
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Australasian Journal of Ultrasound in Medicine
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