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Acute radiation sickness due to critical accidents at a nuclear production facility 因核生产设施发生重大事故而引起的急性辐射病
Q3 Health Professions Pub Date : 2023-05-04 DOI: 10.25016/2541-7487-2023-0-1-05-12
T. Azizova, M. B. Moseeva, K. Briks
Introduction. Nuclear accidents are rare, however, today they cannot be entirely excluded. Thereupon the wealth of global experience is of particular value for prediction of outcomes that potentially follow short-term exposures to ionizing radiation at high dose rates.The objective is to describe clinical simptoms and signs in workers exposed to acute gamma-neutron radiation.Methodology. This paper considers healths effects after radiation exposure due to a critical accident that happened on January, 2 1958 during operations with an experimental flask containing uranium nitrate solution at the Mayak PA. During accident four workers were exposed to short-term gamma-neutron radiation and subsequently suffered from acute radiation syndrome of different severity degree.Results and discussion.  Symptoms of the initial response, development of disorders in various organs and systems and the course of the acute radiation syndrome in exposed individuals are described.Conclusion. Multiple organs or tissues are involved in severe acute radiation syndrome at an early period after acute exposure, at that cardiovascular collapse is the most critical physiological state. Multiple organs or tissues failure in the longtrem period after acute exposure is a secondary manifestation both of the primary nonspecific response to radiation and specific radiation-induced direct damage of highly sensitive cells
介绍。核事故是罕见的,然而,今天它们不能被完全排除。因此,丰富的全球经验对于预测短期高剂量率电离辐射照射后可能出现的后果特别有价值。目的是描述暴露于急性γ -中子辐射的工人的临床症状和体征。本文考虑了1958年1月2日在Mayak PA使用装有硝酸铀溶液的实验烧瓶进行操作时发生的重大事故所造成的辐射暴露对健康的影响。在事故中,四名工人受到短期γ -中子辐射,随后患上不同程度的急性辐射综合征。结果和讨论。本文描述了受照者最初反应的症状、各器官和系统疾病的发展以及急性辐射综合征的过程。严重急性辐射综合征在急性照射后早期多器官或组织受累,其中心血管衰竭是最关键的生理状态。急性暴露后长期内多器官或组织功能衰竭是对辐射的原发性非特异性反应和特异性辐射引起的高敏感细胞直接损伤的继发性表现
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引用次数: 0
Study of road traffic injuries and deaths among the Federal Fire Service personnnel of the EMERCOM of Russia 对俄罗斯联邦消防委员会联邦消防人员道路交通伤亡情况的研究
Q3 Health Professions Pub Date : 2023-03-03 DOI: 10.25016/2541-7487-2022-0-4-66-75
E. V. Bobrinev, A. A. Kondashov, E. Udavtsova, V. Putin
Relevance. Road accidents are one of the main causes of death and injury among the EMERCOM of Russia personnel.The objective is to analyze the circumstances of road traffic occupational injuries and deaths of the Federal Fire Service (FFS) personnel of the EMERCOM of Russia within 2010 to 2021.Methods. The level of occupational injuries in road accidents from 2010 to 2021, depending on the type of transport, type of activity, day of the week and month of the year, was calculated for 10 thousand firefighters, the level of deaths in the line of duty - for 100 thousand firefighters. Arithmetic averages and their errors (M ± m) are presented.Results and discussion. The level of accident-caused injuries of the Russian EMERCOM FFS personnel was (1.52 ± 0.20) cases per 10 thousand people. The dynamics shows a decrease by 3.4 times in the statistics of injuries over 12 years. The rate of accident-caused deaths among the Russian EMERCOM FFS personnel was (2.06 ± 0.28) cases per 100 thousand people. The dynamics of the last two years demonstrates an increase in the statistics of injuries.The road accident injuries constitute 13.2% of the total number of industrial injuries among Russian firefighters. The rate of fatalities caused by road accidents is 25.8% of the total number of firefighters killed in the line of duty.Conclusion. The analysis of the circumstances of accident-caused injuries among the EMERCOM FFS personnel contributes to improved prevention of occupational firefighter injuries and reduces the on-duty firefighter death rate.
的相关性。道路交通事故是造成俄罗斯应急部队人员伤亡的主要原因之一。目的是分析2010年至2021年俄罗斯EMERCOM联邦消防局(FFS)人员道路交通职业伤亡情况。根据交通工具类型、活动类型、一周中的哪一天和一年中的哪一个月,计算了2010年至2021年道路交通事故中职业伤害的水平,计算了1万名消防员的职业伤害水平,计算了10万名消防员因公死亡的水平。给出了算术平均值及其误差(M±M)。结果和讨论。俄罗斯EMERCOM FFS人员的意外伤害水平为(1.52±0.20)例/万人。这一动态表明,在过去12年里,伤病统计数据下降了3.4倍。俄罗斯紧急应急部队FFS人员的事故死亡率为每10万人(2.06±0.28)例。过去两年的动态表明了受伤数据的增加。道路交通事故伤害占俄罗斯消防员工伤总数的13.2%。道路交通事故造成的死亡率占消防员在执勤中死亡总人数的25.8%。对应急应急执行局FFS人员意外伤害情况的分析有助于改进对职业消防员伤害的预防,并降低值班消防员的死亡率。
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引用次数: 0
Prevalence of focal odontogenic infection in patients with class II malocclusion studying at Russian Ministry of Defense institutions of comprehensive education 俄罗斯国防部综合教育机构研究ⅱ类错颌患者局灶性牙源性感染的患病率
Q3 Health Professions Pub Date : 2023-03-03 DOI: 10.25016/2541-7487-2022-0-4-31-39
N. A. Sokolovich, A. A. Saunina, E. S. Mikhailova, I. Soldatov
Relevance. Caries and premature loss of teeth is among the causes of the development of malocclusion. Caries develops with greater frequency on proximal and occlusal surfaces of mandibular first molars, which increases the risk of periapical complications due to late diagnosis of tooth decay. Students of the Russian Ministry of Defense schools for comprehensive education belong to reserve units of law enforcement authorities, agencies and services. Therefore, prevention and sustaining their good health, including dental health, is a top priority.The paper objective is to evaluate the frequency of carious lesions of various surfaces of mandibular molars and their complications in students of educational institutions of the Ministry of Defense of Russia.Methods. We examined 30 first year students with class II malocclusion (K07.20 according to ICD-10) aged 11-12 years, using basic (clinical examination and probing) and additional (questionnaires, photo protocol, radiography) research methods. All patients underwent cone beam computed tomography (CBCT) in natural occlusion with a resolution of 17Ч15.Results and discussion. 45 % of the examined students revealed latent carious lesions of the enamel below the level of the equator, predominantly localized on the tooth medial surface. At the same time, carious lesions communicating with the tooth cavity in 60.9 % of cases were localized on the contact surfaces (Class II according to Black), in 39.1% - on the chewing surface (Class I according to Black). Periapical foci of destruction were found in 38.3 % of cases.Conclusion. When diagnosing and planning orthodontic treatment of malocclusion in students of the Russian Ministry of Defense institutions, it is important to refer the patient to CBCT in order to timely detect hidden carious lesions of the enamel below the equator and prevent the transition of uncomplicated caries into complicated cases.
的相关性。龋齿和牙齿过早脱落是导致错牙合发展的原因之一。在下颌第一磨牙的近端和咬合面发生龋齿的频率更高,由于龋齿的诊断较晚,这增加了根尖周围并发症的风险。俄罗斯国防部综合教育学校的学生属于执法机关、机构和服务的预备役单位。因此,预防和保持他们的健康,包括牙齿健康,是重中之重。本文的目的是评估俄罗斯国防部教育机构学生下颌磨牙各表面龋齿病变的发生率及其并发症。采用基础(临床检查和探探)和附加(问卷调查、摄影、x线摄影)的研究方法,对30名11-12岁的一年级II型错牙合(ICD-10 K07.20)学生进行了调查。所有患者在自然闭塞时均行锥束计算机断层扫描(CBCT),分辨率为17Ч15。结果和讨论。在接受检查的学生中,有45%的人在赤道以下的牙釉质上发现了潜在的龋病,主要集中在牙齿的中表面。同时,与牙腔相通的龋齿病变60.9%发生在接触面(Black分类为II类),39.1%发生在咀嚼面(Black分类为I类)。根尖周围病变发生率为38.3%。在俄罗斯国防部院校学生错牙合的诊断和规划正畸治疗时,建议患者进行CBCT检查,以便及时发现赤道以下牙釉质隐匿性龋齿病变,防止单纯龋齿向复杂病例过渡。
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引用次数: 0
Diagnostic significance of the level of short chain fatty acids and aminothiols in the EMERCOM of Russia response officers with risk factors for circulatory system diseases 短链脂肪酸和氨基硫醇水平在俄罗斯EMERCOM应对人员与循环系统疾病危险因素的诊断意义
Q3 Health Professions Pub Date : 2023-03-03 DOI: 10.25016/2541-7487-2022-0-4-104-111
I. Shantyr, G. G. Rodionov, S. Dudarenko, M. Sannikov, E. V. Svetkina, E. A. Kolobova, O. A. Ezhova, E. S. Saryan
Relevance. Individuals of stressful professions, including the emergency response officers (firefighters and rescuers) of the Ministry of Emergency Situations of Russia, are prone to the early onset of circulatory system diseases (CSD). At in-depth examinations the CSD detection rate in EMERCOM response officers is above 10%. Earlier studies report that CSD risk factors are widespread among EMERCOM of Russia response officers. Therefore, it is relevant to identify the predisposition to CSD as soon as possible in order to maintain good health and longevity among highly qualified professionals of the Ministry of Emergency Situations of Russia.The pathophysiological mechanism underlying progression of atherosclerosis affects complicated interactions between vasculature, immune system and lipid metabolism. Evidence shows that intestinal microbiome exacerbates all compound risk factors for atherosclerosis, both directly and indirectly, thus playing an important role in CSD development.Numerous studies revealed that elevated levels of plasma homocysteine and other aminothiols strongly correlate with manifestations of vascular dysfunction in atherosclerosis, coronary heart disease, myocardial infarction, stroke, and thrombosis, which makes it possible to isolate homocysteine as an independent risk factor for CSD progression.Our objective is to evaluate intestinal microbiome metabolism indicators and plasma aminothiols as early CVD risk markers in emergency response officers of the Ministry of Emergency Situations of Russia.Methodology. A comprehensive clinical and laboratory examination was performed in 96 emergency response male officers of the Russian Ministry of Emergency Situations at a regular medical check-up in the outpatient center of the Nikiforov Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia, St. Petersburg. The average age of response officers was (35.9 ± 0.8) years, with average work experience in the EMERCOM of Russia of (8.8 ± 0.5) years. All emergency response officers were split in 3 groups: group 1 included 56 practically healthy males, group 2 - 20 males with risk of CVD development, group 3 - 20 males with established CVD diagnosis. Chromatography with mass-spectrometric determination of short-chain fatty acids (SCFAs), trimethylamine N-oxide (TMAO) and aminothiols was performed in plasma samples from all examined patients.Results and analysis. TMAO level was elevated by 30 % in group 3 compared to group 1. Acetic acid level decrease by 32 % was found in group 2 and by 45 % in group 3 compared to group 1.Plasma valeric and butyric acids were decreased by 1.9 and 2.5 times respectively in group 3 compared to group 1, as well as by 2 times in group 3 compared to group 2. It was found that in group 3 cystine concentration was decreased by 30 % compared to group 1 and reduced glutathione was elevated by 2 times compared to group 2.Conclusion. The revealed changes in the level of SCFA, aminothiols and TMAO in emerge
的相关性。从事压力较大职业的个人,包括俄罗斯紧急情况部的应急官员(消防员和救援人员),容易早发循环系统疾病(CSD)。在深入调查中,紧急事故应急中心的人员对CSD的检出率超过10%。早期的研究报告称,CSD风险因素在俄罗斯应急军官中普遍存在。因此,有必要尽快查明易患慢性疾病的人,以便使俄罗斯紧急情况部的高素质专业人员保持健康和长寿。动脉粥样硬化的病理生理机制影响血管系统、免疫系统和脂质代谢之间复杂的相互作用。有证据表明,肠道微生物群直接或间接地加剧了动脉粥样硬化的所有复合危险因素,因此在CSD的发展中起着重要作用。大量研究表明,血浆同型半胱氨酸和其他氨基硫醇水平升高与动脉粥样硬化、冠心病、心肌梗死、卒中和血栓形成等血管功能障碍的表现密切相关,这使得同型半胱氨酸成为CSD进展的独立危险因素成为可能。我们的目的是评估肠道微生物代谢指标和血浆氨基硫醇作为俄罗斯紧急情况部应急反应官员的早期心血管疾病风险标志物。在圣彼得堡俄罗斯紧急情况部Nikiforov俄罗斯紧急和辐射医学中心门诊中心的定期体检中,对俄罗斯紧急情况部的96名男性应急官员进行了全面的临床和实验室检查。响应人员的平均年龄为(35.9±0.8)岁,在俄罗斯EMERCOM的平均工作经验为(8.8±0.5)年。所有应急响应人员被分为3组:1组包括56名实际健康的男性,2 - 20名有心血管疾病发展风险的男性,3 - 20名确诊为心血管疾病的男性。采用色谱-质谱法测定所有患者血浆样品中的短链脂肪酸(SCFAs)、三甲胺n -氧化物(TMAO)和氨基硫醇。结果和分析。与1组相比,3组TMAO水平升高30%。与1组相比,2组和3组的乙酸水平分别下降了32%和45%。3组血浆戊酸和丁酸分别比1组降低1.9倍和2.5倍,比2组降低2倍。结果发现,3组胱氨酸浓度比1组降低30%,还原性谷胱甘肽浓度比2组升高2倍。俄罗斯紧急情况部应急人员中SCFA、氨基硫醇和TMAO水平的变化表明代谢失衡,这扩大了我们对肠道微生物群与人体相互作用的认识。这对俄罗斯紧急情况部应急官员的CSD早期诊断、预防和纠正至关重要。
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引用次数: 0
Biochemical effects in deep-sea divers exposed to aquatic environmental factors 深海潜水者暴露于水生环境因子的生化效应
Q3 Health Professions Pub Date : 2023-03-03 DOI: 10.25016/2541-7487-2022-0-4-76-82
S. Bychkov, D. P. Zverev, I. Klenkov, A. M. Yarkov, Z. M. Israfilov
Relevance. Diving equipment and diving launch techniques witness continuous improvements, which allow individuals to more effectively perform various tasks underwater. A controlled electronic closed circuit rebreather has been used in amateur diving in our country for more than 20 years. It is therefore necessary to assess the biochemical effects in deep-sea divers wearing deep sea diving equipment to ensure its safety and functionality in professional diving and the activities of dedicated departmental structures.The objective is to assess the biochemical effects in deep-sea divers in controlled electronic closed circuit rebreather, with a similar level of intravascular decompression gas formation under the influence of aquatic environment factors.Methods. During the study, 9 blood biochemical parameters were evaluated using the Fujifilm DRI-CHEM NX500 apparatus in 6 divers before and after deep-sea descents. In total, 14 diving descents were performed in a controlled electronic closed circuit rebreather to depths from 60 to 100 m. Also, after each diving descent, the level of intravascular decompression gas formation was assessed using ultrasonic location with the constant-wave Doppler effect.Results and Discussion. As a result of these studies, a significant increase in the values of transaminases (ALT, AST) and urea was established, associated with increased partial pressure of oxygen in hyperbaric aquatic environment. The results of the analysis revealed that indicators of the CNS oxygen intoxication correlated with K+ ions concentration and glucose levels; a correlation between Na+ ions and Cl- ions concentration was established, as well as the inverse relationship between the concentration of urea and creatinine and the level of intravascular decompression gas formation. It is noteworthy that a correlation was found between the level of intravascular decompression gas formation and the CNS oxygen intoxication, whereby an increase in the CNS oxygen intoxication leads to increased levels of intravascular decompression gas formation.Conclusion. The studied blood biochemical parameters did not go beyond the reference values and had slight individual variations, which confirms the safety of the technology of descents in diving breathing apparatus with a controlled electronic closed circuit rebreather at depths of more than 60 m. The results of the correlation analysis revealed changes in carbohydrate and water-electrolyte metabolism in the body of divers after a deep-sea descent due to the action of an increased partial pressure of oxygen and intravascular decompression gas formation.
的相关性。潜水设备和潜水发射技术不断改进,使个人能够更有效地在水下执行各种任务。电控闭路换气器在我国业余潜水中应用已有20多年的历史。因此,有必要评估佩戴深海潜水设备的深海潜水员的生化效应,以确保其在专业潜水和专门部门结构活动中的安全性和功能性。目的是评估深海潜水员在受控电子闭路换气器中,在类似水平的血管内减压气体形成下,在水生环境因素的影响下的生化效应。在研究中,采用富士DRI-CHEM NX500仪器对6名潜水者在深海潜水前后的9项血液生化指标进行了评价。在控制的电子闭路换气器中,总共进行了14次潜水,深度从60米到100米不等。此外,在每次潜水后,使用具有恒波多普勒效应的超声定位评估血管内减压气体形成水平。结果和讨论。这些研究的结果表明,转氨酶(ALT, AST)和尿素值的显著增加与高压水生环境中氧分压的增加有关。分析结果显示,CNS氧中毒指标与K+离子浓度和葡萄糖水平相关;Na+离子和Cl-离子浓度呈相关关系,尿素和肌酐浓度与血管内减压气体形成水平呈反比关系。值得注意的是,发现血管内减压气体形成水平与中枢神经系统氧中毒之间存在相关性,即中枢神经系统氧中毒的增加导致血管内减压气体形成水平的增加。所研究的血液生化参数均未超过参考值,且个体差异较小,证实了60 m以上深度使用受控电子闭路换气器潜水呼吸器下沉技术的安全性。相关性分析的结果揭示了深海潜水后潜水员体内碳水化合物和水电解质代谢的变化,这是由于氧气分压增加和血管内减压气体形成的作用。
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引用次数: 0
Prehospital care according to the principles of Damage Control Resuscitation in the conditions of modern warfare (literature review) 现代战争条件下基于损伤控制复苏原则的院前护理(文献综述)
Q3 Health Professions Pub Date : 2023-03-03 DOI: 10.25016/2541-7487-2022-0-4-55-65
Y. Shapkin, P. Seliverstov, N. Y. Stekolnikov, V. V. Ashevskiy
Relevance. Bleeding and hemorrhagic shock are the leading cause of potentially preventable deaths in combat casualties. The concept of pre-hospital injury control Remote Damage Control Resuscitation is becoming an integral part of care in the wounded with shock in the field. The significance of prehospital care provision according to the principles of Damage Control Resuscitation is increasing in future “multidomain battlefield”.The objective is to consider the effectiveness and features of prehospital care provision according to the principles of DCR in armed conflicts of the last two decades (in Afghanistan, Iraq, Africa, the Middle East).Methodology. A search was made for scientific articles in the PubMed database and the Scientific Electronic Library (eLIBRARY.ru), published from 2017 to 2022.Results and Discussion. Prehospital care according to the principles of Damage Control Resuscitation includes temporary arrest of bleeding, infusion therapy as part of hemostatic resuscitation and permissive hypotension, adequate respiratory support, prevention and elimination of hypothermia, and prompt evacuation to the stage of surgical care. Effective means to stop bleeding in combat casualties are modern hemostatic tourniquets, pelvic bandage, hemostatic dressings with koalin and chitosan. Resuscitation endovascular balloon occlusion of the aorta is recognized as a promising method for stopping internal bleeding. The basis of hemostatic resuscitation on the battlefield is the earlier transfusion of blood or its components in combination with the introduction of tranexamic acid and calcium preparations. Group O (I) whole blood with low titer anti-A and anti-B antibodies, lyophilized plasma and fibrinogen concentrate offer logistical advantages for combat use.Conclusion. Pre-hospital care according to the principles of Damage Control Resuscitation is effective and can significantly reduce mortality among those injured in combat operations.
的相关性。在战斗伤亡中,出血和失血性休克是本可预防的死亡的主要原因。院前损伤控制的概念、远程损伤控制复苏正在成为战地休克伤员护理的重要组成部分。在未来的“多域战场”中,根据损伤控制复苏原则提供院前护理的重要性日益增加。目的是根据过去二十年武装冲突(阿富汗、伊拉克、非洲、中东)中DCR的原则,考虑院前护理提供的有效性和特点。检索了PubMed数据库和科学电子图书馆(eLIBRARY.ru)中2017年至2022年发表的科学文章。结果和讨论。根据损害控制复苏原则进行的院前护理包括暂时止血、输液治疗作为止血复苏的一部分和允许性低血压、充分的呼吸支持、预防和消除体温过低,以及迅速转移到手术护理阶段。现代止血止血带、盆腔绷带、koalin和壳聚糖止血敷料是战斗伤员止血的有效手段。复苏血管内球囊阻断主动脉被认为是一种很有前途的止血方法。战场上止血复苏的基础是早期输血或其成分,并结合氨甲环酸和钙制剂的引入。具有低效价抗a、抗b抗体的O (I)型全血、冻干血浆和纤维蛋白原浓缩物为作战提供了后勤保障优势。根据损害控制复苏原则进行院前护理是有效的,可以显著降低战斗行动中受伤人员的死亡率。
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引用次数: 0
Assessment of risk susceptibility score in future rescue technicians 未来救援技术人员风险敏感性评分评估
Q3 Health Professions Pub Date : 2023-03-03 DOI: 10.25016/2541-7487-2022-0-4-112-117
A. Sokolovskaya, O. V. Kazaeva
The relevance of the paper is due to the growing need for qualified personnel in rescue teams qualified to effectively fulfill their professional duties, as well as due to modern trends to upgrade the system of secondary vocational education, which is bound to affect the training of future rescue technicians.The objective is to assess the risk preparedness among college students specializing in Emergency Protection within different courses of study.Methods. Individual risk preparedness assessment was carried out among 1st to 4th year college students utilizing the method by G. Schubert.Results and discussion. As a result of the study, significant difference in risk preparedness score was identified between 1st and 4th year students: 1st year students are less inclined to take risks compared to their 4th year fellows.Conclusion. Enrollment of new recruits requires that educational organizations exercise professional discretion and provide medical counseling throughout professional training across various disciplines to ensure that future rescuers successfully undergo professional adaptation, acquiring appropriate models of behavior and psychological risk preparedness from as early as their 1st academic year.
本文的相关性是由于救援队伍对合格人员的需求日益增长,合格人员能够有效地履行其专业职责,以及现代中等职业教育体系升级的趋势,这必然会影响未来救援技术人员的培养。本研究的目的是评估不同专业紧急防护专业大学生的风险准备情况。采用G. Schubert的方法对一至四年级大学生进行个体风险准备评估。结果和讨论。研究结果表明,一年级学生和四年级学生在风险准备得分上存在显著差异:一年级学生比四年级学生更不愿意冒险。招收新兵要求教育机构行使专业自由裁量权,并在各个学科的专业培训过程中提供医疗咨询,以确保未来的救援人员早在第一学年就成功地进行专业适应,获得适当的行为模式和心理风险准备。
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引用次数: 0
Large-scale emergencies, risks of social and biomedical consequences in the leading countries and globally (2012—2021) 主要国家和全球的大规模突发事件、社会和生物医学后果风险(2012-2021年)
Q3 Health Professions Pub Date : 2023-03-03 DOI: 10.25016/2541-7487-2022-0-4-83-103
V. Evdokimov
Relevance: Large-scale emergencies (LSE) cause critical disruption in routine activities, while the elimination requires profound redeployment of workforce and resources.The objective is to analyse the dynamics and risks of large-scale emergencies, as well as their social and biomedical consequences in a few individual countries and globally over the past 10 years (2012-2021).Methods: The study is based on global large-scale emergency indicators as reported in the Emergency Events Database (EM-DAT: OFDA/CRED) [https://www.emdat.be/]. All emergencies are split in two generalized groups - natural (natural disasters) and man-made. Risks of social and biomedical consequences of emergencies were calculated for 1 million people (10-6). Medians, upper and lower quartiles for LSE indicators and their consequences (Me [q25; q75]) are specified. The data is dynamically presented as a set of polynomial trends of the 2nd order.Results and discussion. According to EM-DAT, 5533 large-scale emergencies were recorded worldwide in 2012-2021, including 3807 (67.2%) natural and 1814 (32.8%) man-made events. It turned out that the global risks of exposure to emergencies, death, injury (illness) and homelessness were higher in natural emergencies than in man-made ones. The origin of large-scale natural emergencies was as follows: geophysical - 301 (7.9 %), meteorological - 1238 (32.5 %), climatological -272 (7.1 %), hydrological - 1780 (46.9 %) and biological - 215 (5.6 %). Most of the victims were observed during hydrological emergencies, median - 34.8 million people or 0.45 % of the world's population. The most serious bio-medical consequences were observed in meteorological emergencies (risk of death 0.55 • 10-6, risk of injury or illness 2.38 • 10-6), social consequences were most serious in case of hydrological and meteorological emergencies (risk of homelessness 35,8 • 10-6 and 16.1 • 10-6 respectively), economic consequences were most serious in climatological and meteorological emergencies (average economic loss of 1 large scale emergency makes 1 billion 727 million and 1 billion 600 million USA dollars respectively). Large-scale man-made emergencies included 225 industry-related (13.1%), 1206 transport (70%) and 291 domestic (16.9 %) events. The most serious bio-medical consequences were observed in transport emergencies (risk of death 0.54 • 10-6, risk of injury or illness 0.25 • 10-6), social consequences were most serious in domestic emergencies (risk of homelessness 1.12 • 10-6). All large-scale emergencies included 648 (11.7 %) reported for Europe, 2281 (41.2 %) for Asia, 1167 (21.1 %) for the Americas, 1279 (23.1 %) for Africa and 158 (2.1 %) for Australia. As a rule, risks of biomedical and social consequences of large-scale emergencies in leading countries under consideration (China, Germany, India, Japan and the USA) were lower than global risks. Information on domestic large-scale emergencies obtained by Russian experts and EM-DAT staff requires fu
相关性:大规模突发事件(LSE)对日常活动造成严重干扰,而消除突发事件需要对劳动力和资源进行深刻的重新部署。其目标是分析过去10年(2012-2021年)在个别国家和全球范围内发生的大规模紧急情况的动态和风险,以及其社会和生物医学后果。方法:该研究基于紧急事件数据库(EM-DAT: OFDA/CRED) [https://www.emdat.be/]中报告的全球大规模紧急事件指标。所有紧急情况可分为两大类——自然灾害和人为灾害。对100万人计算了突发事件的社会和生物医学后果风险(10-6)。LSE指标的中位数、上、下四分位数及其后果(Me [q25;Q75])。数据动态地呈现为一组二阶多项式趋势。结果和讨论。EM-DAT数据显示,2012-2021年全球共发生5533起大规模突发事件,其中自然事件3807起(67.2%),人为事件1814起(32.8%)。结果表明,全球面临紧急情况、死亡、受伤(疾病)和无家可归的风险在自然紧急情况下高于人为紧急情况。大规模自然突发事件的成因依次为:地球物理301次(7.9%)、气象1238次(32.5%)、气候272次(7.1%)、水文1780次(46.9%)、生物215次(5.6%)。大多数受害者发生在水文紧急情况期间,中位数为3480万人,占世界人口的0.45%。气象紧急情况造成的生物医学后果最为严重(死亡风险0.55·10-6,受伤或患病风险2.38·10-6),水文和气象紧急情况造成的社会后果最为严重(无家可归风险分别为35、8·10-6和16.1·10-6)。气候和气象突发事件的经济后果最为严重(1次大规模突发事件的平均经济损失分别为17.27亿美元和16亿美元)。大型人为突发事件包括225起与工业有关的事件(13.1%),1206起(70%)和291起(16.9%)。在交通紧急情况下,生物医学后果最为严重(死亡风险0.54·10-6,受伤或生病风险0.25·10-6),在家庭紧急情况下,社会后果最为严重(无家可归风险1.12·10-6)。所有大规模突发事件中,欧洲报告发生648起(11.7%),亚洲报告发生2281起(41.2%),美洲报告发生1167起(21.1%),非洲报告发生1279起(23.1%),澳大利亚报告发生158起(2.1%)。通常,在考虑的主要国家(中国、德国、印度、日本和美国),大规模突发事件的生物医学和社会后果风险低于全球风险。俄罗斯专家和EM-DAT工作人员获得的关于国内大规模紧急情况的信息需要进一步同步。结论:计算出的指标可用于确定是否需要制定预防突发事件或将其后果降至最低的区域和全球措施。
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引用次数: 0
Prospects of Xenon Application in Functional Recovery and Rehabilitation of Patients Working in Extreme Occupational Environments 氙气在极端职业环境患者功能恢复与康复中的应用前景
Q3 Health Professions Pub Date : 2023-03-03 DOI: 10.25016/2541-7487-2022-0-4-40-54
I. Ushakov, A. O. Pyatibrat
Relevance. Professionals working in extreme environments (army officers, police officers, pilots, divers, firefighters, rescue workers, etc.) are susceptible to overstraining their functional reserves, causing occupational overexposure or even death. It is therefore pivotal to optimize the functional condition of individuals working in extreme occupational environment.The objective is to analyse the prospects for xenon medical application, including to promote functional optimization and occupational resilience in professionals working in extreme occupational environment.Methods. The authors studied the research papers published in the Russian Science Citation Index [https://elibrary.ru/] and PubMed [https://pubmed.ncbi.nlm.nih.gov] over the last decade.Results and Discussion. Current research analysis has revealed numerous investigations regarding xenon application in addiction medicine, treatment of post-traumatic stress disorders, and improvement of physiological reserve and occupational resilience, as well as in anesthesiology. Regrettably, our review of Russian and international publications has failed to answer the pivotal issue regarding pharmacological mechanisms behind xenon action. A few research papers hypothesized without evidence that ionotropic glutamate receptors (NMDA-receptors) might be involved in antinociceptive effects.Conclusion. Xenon is a promise and can be appropriately applied in the treatment and rehabilitation of individuals working in extreme occupational environments.
的相关性。在极端环境中工作的专业人员(军官、警察、飞行员、潜水员、消防员、救援人员等)很容易使他们的功能储备过度紧张,导致职业过度暴露甚至死亡。因此,优化在极端职业环境中工作的个体的功能状况是至关重要的。目的是分析氙在医学上的应用前景,包括促进极端职业环境下专业人员的功能优化和职业弹性。作者研究了过去十年在俄罗斯科学引文索引[https://elibrary.ru/]和PubMed [https://pubmed.ncbi.nlm.nih.gov]上发表的研究论文。结果和讨论。目前的研究分析显示,氙在成瘾药物、创伤后应激障碍的治疗、生理储备和职业恢复力的改善以及麻醉学方面的应用有许多研究。遗憾的是,我们对俄罗斯和国际出版物的回顾未能回答关于氙气作用背后的药理学机制的关键问题。一些研究论文在没有证据的情况下假设嗜离子性谷氨酸受体(nmda受体)可能参与抗伤害感受作用。氙是一个有希望的,可以适当地应用于在极端职业环境中工作的个人的治疗和康复。
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引用次数: 1
Significance of musculoskeletal and connective tissue parameters as health indicators in Federal Fire-Fighting Service officers of the State Fire-Fighting Service of the EMERCOM of Russia 肌肉骨骼和结缔组织参数作为健康指标在俄罗斯EMERCOM国家消防服务局联邦消防服务人员中的意义
Q3 Health Professions Pub Date : 2023-03-02 DOI: 10.25016/2541-7487-2022-0-4-05-30
S. Aleksanin, V. Evdokimov, V. Rybnikov
Relevance. The job of Federal Fire-Fighting Service (FFS) officers of the State Fire-Fighting Service of the EMERCOM of Russia is among the global top 10 occupations with evident risk of health functional reserves depletion, prevalence of early occupational diseases, injuries and even death. Traditionally, investigators focus on circulatory diseases and how they affect firefighters’ occupational health.The objective is to provide  research-based evidence showing that musculoskeletal and connective tissue parameters provide a reliable estimate of the health status in Russian Federal Fire-Fighting Service officers.Methodology. The authors analyzed the research papers included in the Russian Science Citation Index mostly within the last 10 years and the studies carried out at the Nikiforov Russian Center of Emergency and Radiation Medicine and at the All-Russian Research Institute for Fire Protection of the EMERCOM of Russia. Morbidity was calculated in ppm (‰), industrial injury and primary disability rates were estimated per 10,000 (×104), mortality (deaths) – per 100,000 (×105) people. The indicators dynamics was estimated based on dynamic sets of data applying the 2nd  order polynomial trend; the Pearson correlation coefficient was utilized to verify consistency of the trends.Results and analysis. In 2003–2015 the average annual incidence rate of cases with labor losses (across all ICD-10 chapters of diseases) among the EMERCOM Federal Fire Service officers was (407.0 ± 30.4) ‰ which was statistically significantly lower than among the Russian armed forces officers (508.5 ± 35.6) ‰ (p < 0.05); the number of lost workdays was higher, i.e. (5139 ± 402) and (4174 ± 123) ‰ respectively (p < 0.05). Consistency in the dynamics of case number, rate of lost workdays, and day/incident ratio among firefighters and military officers is low and negative, potentially due to the impact of different factors on lost workdays rate. Assuming the macrosocial factors are identical, organisational  and/or occupational factors could be the key contributors to labor losses. Rates of injuries, poisoning and other external impacts (chapter XIX in ICD-10), as well as musculoskeletal and connective tissue diseases (chapter XIII) play the leading  role in morbidity dynamics among firefighters. The mortality rate among the Russian EMERCOM FFS officers with chapter XIX injuries was 8.5 times lower than that among the Russian male population, although the population cohort was 2.5 times more numerous. Occupational injury rate of (14.66 ± 2.01) • 10–4 of injuries/(firefighter • year) and firefighter fatalities (8.53 ± 0.83) • 10–5 deaths/(firefighter • year) in 2006–2020 were statistically significantly lower than among economically active working male population  in Russia: (22.73 ± 2.8) • 10–4 (p < 0.01) and (13.23 ± 1.12) • 10–5 (p < 0.05) respectively. Considering the work schedule of firefighters, the annual amount of work in extreme environments was carried out within 6
的相关性。俄罗斯联邦消防委员会国家消防局联邦消防局官员的工作是全球十大职业之一,具有明显的健康功能储备枯竭、早期职业病流行、受伤甚至死亡风险。传统上,调查人员关注循环系统疾病及其如何影响消防员的职业健康。目的是提供基于研究的证据,表明肌肉骨骼和结缔组织参数为俄罗斯联邦消防服务人员的健康状况提供了可靠的估计。作者分析了俄罗斯科学引文索引(Russian Science Citation Index)收录的研究论文,主要是近10年来的研究论文,以及在Nikiforov俄罗斯急救和辐射医学中心和俄罗斯EMERCOM全俄消防研究所进行的研究。发病率以ppm(‰)计算,工伤和初级致残率估计为每10万人(×104),死亡率(死亡)-每10万人(×105)。采用二阶多项式趋势对动态数据集进行指标动态估计;利用Pearson相关系数验证趋势的一致性。结果和分析。2003-2015年,EMERCOM联邦消防人员(ICD-10所有章节疾病)的年均劳动损失病例发生率为(407.0±30.4)‰,低于俄罗斯武装部队军官(508.5±35.6)‰(p < 0.05);损失工作日数较高,分别为(5139±402)‰和(4174±123)‰(p < 0.05)。在消防员和军官中,案件数量、工作日损失率和日/事故率的动态一致性较低且为负值,这可能是由于不同因素对工作日损失率的影响。假设宏观社会因素是相同的,组织和/或职业因素可能是劳动力流失的关键因素。受伤、中毒和其他外部影响的比率(《国际疾病分类-10》第十九章)以及肌肉骨骼和结缔组织疾病(第十三章)在消防员的发病率动态中起主要作用。受第19章伤的俄军应急部队FFS军官的死亡率是俄军男性人口死亡率的8.5倍,尽管男性人口数量是男性人口的2.5倍。俄罗斯2006-2020年职业伤害率为(14.66±2.01)•10-4 /(消防员•年),消防员死亡人数为(8.53±0.83)•10-5 /(消防员•年),分别低于经济活动男性人口的(22.73±2.8)•10-4 (p < 0.01)和(13.23±1.12)•10-5 (p < 0.05),具有统计学意义。考虑到消防员的工作进度,极端环境下的年度工作量在6个月内完成;而灭火和消除其他紧急情况所造成的工业创伤,按12个月计算,至少应该增加一倍。俄罗斯联邦消防局雇员的初级残疾水平为(15.98±0.99)•10-4,即统计可靠地低于俄罗斯18-44岁工作人口(25.51±1.19)•10-4 (p < 0.001)。一方面,数据表明EMERCOM FFS员工的劳动设置和劳动保护是有效的,而另一方面,俄罗斯成年人口的残疾率仍然处于较高水平。虽然没有完全消除负面的职业影响(即疾病、伤害),但可以将其减少到最低限度。预防职业病,特别是创伤和肌肉骨骼疾病的早期发病,具有巨大的健康保护潜力,可确保应急管理机构FFS雇员的职业寿命。
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引用次数: 0
期刊
Medico-Biological and Socio-Psychological Issues of Safety in Emergency Situations
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