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Slow Progressing Localized Tumor Like Pharyngeal Mass: What Is Your Diagnosis? 进展缓慢的局部肿瘤如咽部肿块:你的诊断是什么?
Pub Date : 2020-11-03 DOI: 10.33552/ojor.2020.04.000578
S. Touihmi
Introduction: Amyloidosis is an idiopathic disorder characterized by the extracellular deposition of normally soluble proteins in an abnormal fibrillar form. Pharyngeal involvement is rare. Case summary: 24 years old man consulted for chronic bilateral nasal obstruction, associated with upper dysphagia to solids. Nasal endoscopy found multiples masses involving the the pharynx. A cervical computed tomography (CT) scan of the neck had shown tissular heterogeneous process infiltrating the walls of the nasopharynx, oropharynx: soft palate, and the anterior wall of the hypopharynx. A direct laryngoscopy under general anesthesia was realized. The anatomopathological examination of the hypopharyngeal biopsy sample found amorphous acellular interstitial deposits, marked by Congo red, showing yellow-green apple birefringence under polarized light. Immunohistochemistry diagnosed type AL amyloidosis. The amyloidosis assessment to rule out systemic involvement showed no abnormalities. The patient did well over the next several months, but recurrence of the pharyngeal amyloid tumor necessitated additional conservative endoscopic excisions in the 7 months follow up. Discussion: Amyloidosis in the head and neck is a rare and benign condition that usually takes the form of localized amyloidosis, Pharyngeal involvement is rare. Clinical symptomatology and imaging are poorly specific for pharyngeal involvement, macroscopically, the diagnosis is anatomopathological. Given the rarity of this disease, it is essential to rule out systemic involvement. Amyloid tumors in the pharynx are difficult to treat and commonly recur despite surgical excision.
简介:淀粉样变性是一种特发性疾病,其特征是正常可溶性蛋白以异常纤维状形式在细胞外沉积。咽部受累很少见。病例总结:24岁男性,因慢性双侧鼻塞就诊,伴有上肢固体吞咽困难。鼻内窥镜检查发现多发性肿块累及咽部。颈部计算机断层扫描(CT)显示组织异质过程浸润鼻咽部、口咽部、软腭和下咽前壁。实现了全麻下直接喉镜检查。下咽活检标本解剖病理检查发现无定形脱细胞间质沉积,刚果红标记,偏振光下呈黄绿色苹果双折射。免疫组化诊断为AL型淀粉样变。排除全身累及的淀粉样变评估未见异常。在接下来的几个月里,患者的情况很好,但在7个月的随访中,咽淀粉样蛋白肿瘤复发,需要进行额外的保守内镜切除。讨论:头颈部淀粉样变是一种罕见的良性疾病,通常以局部淀粉样变的形式出现,很少累及咽部。临床症状和影像学对咽部受累特异性差,宏观上,诊断是解剖病理学。鉴于此病罕见,必须排除全身性累及。咽淀粉样蛋白肿瘤很难治疗,尽管手术切除,但通常会复发。
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引用次数: 0
The Incidence of Post-Septoplasty Complications Among Patients with Deviated Nasal Septum in Relation to Gender and Age 鼻中隔偏曲成形术后并发症与性别、年龄的关系
Pub Date : 2020-11-02 DOI: 10.33552/ojor.2020.04.000576
Abdulwahid S Al Qahtani
Background: A deviated septum can present at birth, becomes curved during growth, or can be traumatic due to nasal and facial injury. A deviated septum is usually asymptomatic, but sometimes may be present with difficulty breathing through the nose, nasal congestion, sinus infections, nosebleeds, sleep problems, headache, or postnasal drip. Many methods and guidelines have been scheduled to treat and manage acute nasal trauma; however, re-establishment of anatomical deformities and function is still a challenge. Septoplasty is the required surgical intervention for patients to relieve their nasal obstruction. Aim: To detect the incidence of post-septoplasty complications and their relationship with patients’ age and gender among cases with nasal septum deviation. Methodology: A retrospective Electronic record-based study was conducted. This study included patients diagnosed clinically with a deviated nasal septum (DNS) and have undergone surgical intervention (Septoplasty) at Khamis Mushait General Hospital. Data extracted included patients’ demographics and postoperative recorded complications. Results: The study included a total sample of 93 patients. Nasal obstruction was the commonest symptom among patients. As for postoperative complications, nasal obstruction represents nearly one-third of the cases followed by external nasal deformity, and smell disturbance. Conclusion: In conclusion, our study revealed that the only significant post-operative complication incidence in relation with both gender and age groups is a nasal deformity. Nasal obstruction is the most common postoperative complications recorded in general and among male and female patients as well as in all age groups although there is no significant relation to both gender and age groups. Large-scale researches should be conducted to give more understanding and further explanation.
背景:鼻中隔偏曲可以在出生时出现,在生长过程中变得弯曲,或者由于鼻腔和面部损伤而造成的创伤。鼻中隔偏曲通常是无症状的,但有时可能表现为通过鼻子呼吸困难、鼻塞、鼻窦感染、流鼻血、睡眠问题、头痛或后鼻滴涕。许多方法和指南已经安排治疗和管理急性鼻外伤;然而,解剖畸形和功能的重建仍然是一个挑战。鼻中隔成形术是缓解鼻塞的必要手术干预。目的:探讨鼻中隔偏曲术后并发症的发生率及其与患者年龄、性别的关系。方法:采用回顾性电子记录研究。本研究纳入了临床诊断为鼻中隔偏曲(DNS)并在Khamis Mushait总医院接受手术干预(鼻中隔成形术)的患者。提取的数据包括患者的人口统计数据和术后记录的并发症。结果:本研究共纳入93例患者。鼻塞是患者最常见的症状。术后并发症以鼻塞占近三分之一,其次为外鼻畸形,嗅觉障碍。结论:我们的研究表明,在性别和年龄组中,唯一显著的术后并发症发生率是鼻畸形。鼻塞是一般情况下最常见的术后并发症,在男性和女性患者以及所有年龄组中都有记录,尽管性别和年龄组之间没有明显的相关性。需要进行大规模的研究来给予更多的理解和进一步的解释。
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引用次数: 0
Serious Airway Compromise in Rare Presentation of Posterior Tongue Base Abscess 罕见的后舌根脓肿导致严重气道损害
Pub Date : 2020-10-21 DOI: 10.33552/ojor.2020.03.000575
Mohamed E El-Amin
This is a rare case report of 37 years old lady presented with acute airway compromise after presenting a few times to the emergency department with worsening sore throat and been treated for tonsillitis. Patient oral examination was difficult due to severe trismus but no signs of tonsillitis. Naso-endoscopic examination showed severe swelling of the base of the tongue without any significant signs of recent trauma or other signs of the acute inflammatory process. Imaging showed large posterior tongue base abscess. Drainage of the abscess was achieved through the external approach. The patient recovered well and was discharged home on oral antibiotics. The condition was related to patent foramen caecum of small area which led to abscess formation due to canalisation of bacteria with no obvious source of trauma or oral infections.
这是一个罕见的病例报告,37岁的女士提出了急性气道妥协后,提出了几次的急诊科恶化喉咙痛和扁桃体炎治疗。患者口腔检查困难,因为严重的牙关,但没有扁桃体炎的迹象。鼻内窥镜检查显示舌底严重肿胀,没有任何近期创伤的明显迹象或其他急性炎症过程的迹象。影像学显示舌后基底大脓肿。通过外入路引流脓肿。患者恢复良好,经口服抗生素治疗出院。该病与小面积盲肠孔未闭有关,细菌管化导致脓肿形成,无明显外伤或口腔感染来源。
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引用次数: 0
How We Do It: The Hickey Technique for Removing A Foreign Object from the Nasal Cavity of A Child 我们如何做:从儿童鼻腔中去除异物的吻痕技术
Pub Date : 2020-10-15 DOI: 10.33552/ojor.2020.03.000574
M. Rashid
The removal of foreign bodies from the nose is a common task for emergency departments and otolaryngologists. It is most common in children and those with learning difficulties [1,2]. Intranasal foreign bodies are often benign but can cause nasal obstruction and irritation if not treated. Certain objects, such as button batteries and paired batteries, are locally destructive [3]. Management of foreign bodies generally starts with non-invasive methods such as positive pressure techniques, through instrumental removal and finally as a last resort to removal under a general anaesthetic [1,3]. Because of the cost and increased risk associated with a latter, there is a clear benefit to removing objects without recourse to theatre; but this can be difficult if the patient is an uncooperative child.
从鼻子里取出异物是急诊科和耳鼻喉科医生的一项常见任务。它在儿童和有学习困难的人群中最为常见[1,2]。鼻内异物通常是良性的,但如果不及时治疗,会引起鼻塞和刺激。某些物体,如纽扣电池和成对电池,具有局部破坏性[3]。异物的处理通常从非侵入性方法开始,如正压技术,通过器械取出,最后在全身麻醉下取出[1,3]。由于与后者相关的成本和风险增加,在不诉诸剧院的情况下移除物品显然有好处;但如果病人是一个不合作的孩子,这可能会很困难。
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引用次数: 0
Laryngeal Dystonia with Frequent Stridorous Attacks in Xeroderma Pigmentosum Type A, Would Early Tracheostomy Change the Outcome Case Report and Literature Review A型色斑性干皮病患者喉张力障碍伴频发性发作,早期气管切开术会改变预后吗
Pub Date : 2020-10-13 DOI: 10.33552/ojor.2020.03.000573
Hazim Aleid
Vocal folds dystonia and total vocal folds paralysis in Xeroderma Pigmentosum Type-A (XPA) are considered rare clinical entities that have been recently described in few case reports from the Japanese literature. We report an 11 years old boy with XPA and seizures and history of frequent emergency room (ER) visits to different local hospitals for recurrent inspiratory stridor which was treated as “croup” since the age of 10. The child was brought into our ER for the first time with recurrent, severe stridor and was admitted as a severe case of “croup”. He was treated for approximately two weeks with only minimal improvement. Laryngoscopy showed normal vocal cord appearance with no signs of inflammation. Shortly after discharge, he was re-admitted with stridor, which was noticed to be episodic, exacerbated by irritation, excitation and post oral feeding. Stridor subsides completely during sleep. Repeated laryngoscopy was performed to investigate other potential causes of stridor. Flexible rhino-laryngoscopy showed paradoxical vocal folds movement with glottic closure during inspiration and limited glottic opening upon expiration which is consistent with laryngeal dystonia. This case report represents the history, physical examination and the follow up findings in this XPA young boy with unusual presentation with stridor and rare association with vocal cord dystonia. Additionally, it raises the question of the validity of considering early tracheostomy in such cases to avoid repeated non-otherwise avoidable life-threatening stridorous attacks.
a型着色性干皮病(XPA)的声带张力障碍和全声带麻痹被认为是罕见的临床实体,最近在日本文献的少数病例报告中被描述。我们报告一名11岁男童,患有哮喘病并癫痫发作,并因反复吸气性喘鸣而频繁到不同地方医院就诊,自10岁起作为“群体”治疗。患儿首次就诊时伴有反复发作的严重喘鸣,作为重症“群”病例入院。他接受了大约两周的治疗,改善甚微。喉镜检查显示声带外观正常,无炎症征象。出院后不久,他再次入院,喘鸣,被注意到是间歇性的,加剧刺激,兴奋和口服喂养。在睡眠中喘鸣会完全消失。反复喉镜检查,以调查其他可能的原因喘鸣。柔性鼻喉镜检查显示吸气时声门关闭,呼气时声门打开有限,声带运动矛盾,与喉张力障碍一致。本病例报告报告了该病例的病史、体格检查和随访结果,该病例表现不寻常,伴有喘鸣和罕见的声带张力障碍。此外,它提出了在这种情况下考虑早期气管切开术以避免重复的非其他可避免的危及生命的发作的有效性问题。
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引用次数: 0
Endoscopic Septoplasty Versus Conventional Septoplasty: Study of 60 Cases 内镜下鼻中隔成形术与常规鼻中隔成形术60例对比研究
Pub Date : 2020-10-07 DOI: 10.33552/ojor.2020.03.000571
Islam Ma
Objective: Traditional surgeries of the nasal septum improve the nasal airway but recent development and advancement of the knowledge about endoscope has changed the treatment modality significantly. Endoscopic approach under good Illumination and magnification lessens the chance of injuring the vital structures and hence lessen the chance of complication. This study is done to compare the conventional method with endoscopic method. Method: Total 60 cases of deviated nasal septum, refractory to conservative medical treatment were randomly selected ÷d into 2 equal groups. 30 patients underwent endoscopic Septoplasty and 30 patients by conventional method. All of them were followed up for 6 months. Results: The age distribution was ranging from 16 to 60. Out of them 28 patients (93.33%) of endoscopic group and 25 patients (83.33%) on conventional group were relieved from symptom. In endoscopic Septoplasty group, along with Septoplasty functional endoscopic sinus surgery was carried out in 4 patients (13.33%). In conventional group 4 patients (16.67%) had intra and postoperative complications like excessive hemorrhage and septal perforation etc.7 patients (23.3%) of conventional Septoplasty group presented with recurrence or persistence of symptom within 6 months of surgery. Conclusion: Though conventional Septoplasty is widely practiced by most ENT surgeons till now, the endoscopic approach can be considered as a better alternative.
目的:传统的鼻中隔手术改善了鼻导气管,但近年来内窥镜知识的发展和进步使其治疗方式发生了显著变化。在良好的光照和放大条件下,内镜入路可减少损伤重要结构的机会,从而减少并发症的机会。本研究是为了比较常规方法和内镜方法。方法:将60例保守治疗难治性鼻中隔偏曲患者随机分为2组。内镜下鼻中隔成形术30例,常规成形术30例。随访6个月。结果:年龄分布在16 ~ 60岁之间。其中内镜组28例(93.33%)症状缓解,常规组25例(83.33%)症状缓解。内窥镜鼻中隔成形术组在鼻中隔成形术的同时,行功能性内窥镜鼻窦手术4例(13.33%)。常规组4例(16.67%)患者出现过多出血、鼻中隔穿孔等术中及术后并发症,常规鼻中隔成形术组7例(23.3%)患者术后6个月内出现复发或症状持续。结论:虽然常规鼻中隔成形术至今仍被大多数耳鼻喉科医生广泛采用,但内镜下鼻中隔成形术是一种更好的选择。
{"title":"Endoscopic Septoplasty Versus Conventional Septoplasty: Study of 60 Cases","authors":"Islam Ma","doi":"10.33552/ojor.2020.03.000571","DOIUrl":"https://doi.org/10.33552/ojor.2020.03.000571","url":null,"abstract":"Objective: Traditional surgeries of the nasal septum improve the nasal airway but recent development and advancement of the knowledge about endoscope has changed the treatment modality significantly. Endoscopic approach under good Illumination and magnification lessens the chance of injuring the vital structures and hence lessen the chance of complication. This study is done to compare the conventional method with endoscopic method. Method: Total 60 cases of deviated nasal septum, refractory to conservative medical treatment were randomly selected &divided into 2 equal groups. 30 patients underwent endoscopic Septoplasty and 30 patients by conventional method. All of them were followed up for 6 months. Results: The age distribution was ranging from 16 to 60. Out of them 28 patients (93.33%) of endoscopic group and 25 patients (83.33%) on conventional group were relieved from symptom. In endoscopic Septoplasty group, along with Septoplasty functional endoscopic sinus surgery was carried out in 4 patients (13.33%). In conventional group 4 patients (16.67%) had intra and postoperative complications like excessive hemorrhage and septal perforation etc.7 patients (23.3%) of conventional Septoplasty group presented with recurrence or persistence of symptom within 6 months of surgery. Conclusion: Though conventional Septoplasty is widely practiced by most ENT surgeons till now, the endoscopic approach can be considered as a better alternative.","PeriodicalId":365490,"journal":{"name":"Online Journal of Otolaryngology and Rhinology","volume":"184 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122351842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Hearing Loss Gene Panel Testing: Considerations for Clinical Practice 听力损失基因面板测试:临床实践的考虑
Pub Date : 2020-09-24 DOI: 10.33552/ojor.2020.03.000569
Alpana Kulkarni
Hearing loss gene panel testing has now been introduced into mainstream NHS (National Health Service) as genetic test which can be offered to families with child with hearing loss. Clinicians requesting this test need to have an understanding of its sensitivity, specificity of this test and its limitations and challenges. They also need to be aware of the ethical issues which may arise by undertaken this test and counsel families accordingly before requesting this test.
听力损失基因小组测试现在已经被引入主流NHS(国民健康服务)作为基因测试,可以提供给有听力损失儿童的家庭。要求进行该检测的临床医生需要了解该检测的敏感性、特异性及其局限性和挑战。他们还需要意识到进行这项测试可能产生的道德问题,并在要求进行这项测试之前向家庭提供相应的咨询。
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引用次数: 0
Maxillary Alveolar Carcinoma: Risk of Recurrence and its Relation with Prognostic Indicators 上颌牙槽癌:复发风险及其与预后指标的关系
Pub Date : 2020-09-17 DOI: 10.33552/ojor.2020.03.000567
Zubair Durrani
Background: Maxillary Alveolar carcinoma is a relatively uncommon entity with occurrence reported between 3.5 to 10% of all oral cancers. Recurrence when occurs locally are particularly difficult to treat due to the close proximity of this region to the infratemporal fossa and the base of skull. There is also a debate when to perform elective neck dissection in these patients. Objectives: The aim of this study was to identify cases with recurrence and correlate its association with various prognostic factors and disease free survival in these patients. Methodology: Overall, 15 cases were identified with maxillary alveolar carcinomas that were treated between 2011 to 2015. Eight of these cases were Squamous cell carcinomas, 5 Adeno carcinomas and 2 Adenocystic carcinomas. T stages, N stage, grade of tumor, surgical margin involvement by the tumor, presence of perineural and lymphovascular invasion were identified as prognostic indicators. The chi-square and Pearson correlation tests were applied to analyze the association between recurrence and these prognostic factors. Results: Recurrence developed in 3 SCC (37.5%) and 1 ADC (20%) patient during the three years period following the treatment. Among the SCC patients, 2 recurrences were local and 1 regional. Recurrence was found to have a strong positive correlation with T stage (r=0.330, p=0.271), surgical margin involvement (r=0.575, p=0.566) and three years disease free survival (r=0.959, p=0.000). A weak positive correlation was also established with tumor grade (r=0.155, p=0.0613) and perineural invasion (r=0.149, p =0.725).
背景:上颌牙槽癌是一种相对罕见的疾病,据报道其发生率在所有口腔癌的3.5%至10%之间。局部复发尤其难以治疗,因为该区域靠近颞下窝和颅底。在这些患者中,何时进行选择性颈部清扫也存在争议。目的:本研究的目的是确定复发病例,并将其与这些患者的各种预后因素和无病生存相关联。方法:我们收集了2011 - 2015年间治疗的15例上颌牙槽癌患者。其中8例为鳞状细胞癌,5例为腺癌,2例为腺囊癌。T分期、N分期、肿瘤分级、肿瘤累及手术切缘、有无神经和淋巴血管浸润被确定为预后指标。应用卡方检验和Pearson相关检验分析复发率与这些预后因素之间的关系。结果:3例SCC(37.5%)和1例ADC(20%)患者在治疗后3年内复发。2例局部复发,1例区域性复发。复发与T分期(r=0.330, p=0.271)、手术缘受累(r=0.575, p=0.566)、3年无病生存率(r=0.959, p=0.000)呈正相关。与肿瘤分级(r=0.155, p=0.0613)和周围神经浸润(r=0.149, p= 0.725)呈弱正相关。
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引用次数: 0
Evaluation of Saccular Function with cVEMP In Patients with Systemic Lupus Erythematosus cemp评价系统性红斑狼疮患者的囊功能
Pub Date : 2020-09-14 DOI: 10.33552/ojor.2020.03.000565
Tuba Turkman
Introduction: Systemic lupus erythematosus (SLE) is a disease characterized by sensorineural hearing loss, tinnitus and vestibular disorders. Studies have shown that vestibular symptoms are quite common in patients with SLE. The aim of this study was to evaluate the relationship between cervical vestibular evoked myogenic potential (cVEMP) test and saccular dysfunction and the possible relationship between SLE and vertigo in patients with SLE. Materials and methods: Forty-six SLE patients (aged 18-40 years) and forty healthy volunteers (aged 20-40 years) were included in the study. Patients with SLE were questioned about their duration of the disease, hearing status and balance. Pure-tone audiometry, tympanometry and cVEMP tests were performed to all patients in SLE and control groups. Results: When P1 and N1 latencies were compared by the cVEMP in SLE and control groups, P1 and N1 latencies of the left and right ears of the SLE group were found to be significantly longer than the control group (p <0.05). In twenty-six SLE patients with vertigo, P1 and N1 latencies were significantly longer than patients with SLE without vertigo. There was also a significant relationship between vertigo and duration of the disease (p <0.05). It was found that the rates of saccular dysfunction were higher in patients with SLE. Conclusion: This study showed a strong association between the balance disorders and SLE which is an autoimmune disease. Patients with SLE had a higher rate of saccular dysfunction, and there was a significant relationship between duration of the disease and vertigo.
系统性红斑狼疮(SLE)是一种以感音神经性听力损失、耳鸣和前庭功能障碍为特征的疾病。研究表明,前庭症状在SLE患者中相当常见。本研究的目的是评估颈椎前庭诱发肌源性电位(cemp)测试与SLE患者囊功能障碍的关系,以及SLE与眩晕之间的可能关系。材料与方法:纳入46例SLE患者(18-40岁)和40例健康志愿者(20-40岁)。SLE患者被询问病程、听力状况和平衡。对所有SLE患者和对照组进行纯音听力学、鼓室测量和cVEMP测试。结果:用cemp比较SLE组和对照组的P1、N1潜伏期,SLE组左右耳P1、N1潜伏期明显长于对照组(p <0.05)。在26例伴有眩晕的SLE患者中,P1和N1潜伏期明显长于无眩晕的SLE患者。眩晕与病程也有显著相关(p <0.05)。研究发现SLE患者的囊功能障碍发生率较高。结论:本研究显示平衡障碍与SLE(一种自身免疫性疾病)之间有很强的相关性。SLE患者有较高的囊功能障碍率,且病程与眩晕之间存在显著关系。
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引用次数: 0
Carcinoma Lower Lip: Shaving and Reconstruction under Local Anesthesia 下唇癌:局部麻醉下的刮除与重建
Pub Date : 2020-09-07 DOI: 10.33552/ojor.2020.03.000564
A. Islam
Md Ashraful Islam1*, Tareq Mohammed2, Md Sirajul Islam3, Md Aminul Islam4, Farid Uddin Milki5, ASM Lutfur Rahman6 and Nazmul Hossain Chowdhury7 1Professor and Head, Otolaryngology-Head & Neck Surgery, Bangladesh Medical College Hospital, Bangladesh 2Assistant Registrar ENT, Bangladesh Medical College Hospital, Bangladesh 3Junior Consultant ENT, Bangladesh Medical College Hospital, Bangladesh 4Registrar ENT, Bangladesh Medical College Hospital, Bangladesh 5Consultant ENT, Bangladesh Medical College Hospital, Bangladesh 6Resident Surgeon, Bangladesh Medical College Hospital, Bangladesh 7Assistant Registrar ENT, Bangladesh Medical College Hospital, Bangladesh
Ashraful Islam1*、Tareq Mohammed2、Sirajul Islam3、Aminul Islam4、Farid Uddin Milki5、ASM Lutfur Rahman6和Nazmul Hossain chowdhury教授兼孟加拉医学院医院耳鼻喉头颈外科主任、孟加拉医学院医院耳鼻喉科助理注册医师、孟加拉医学院医院耳鼻喉科助理注册医师、孟加拉医学院医院耳鼻喉科初级顾问医师、孟加拉医学院医院耳鼻喉科注册医师、孟加拉医学院医院耳鼻喉科5顾问医师、孟加拉国医学院医院,孟加拉国6住院外科医生,孟加拉国7孟加拉国医学院医院,孟加拉国耳鼻喉助理注册主任
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引用次数: 0
期刊
Online Journal of Otolaryngology and Rhinology
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