Vision (Switzerland)最新文献

Optic Atrophy (OA) can be associated with the development of microcystic macular edema (MME) in the perifoveal retinal inner nuclear layer (INL). We aimed here to retrospectively determine the prevalence of MME in patients with non-glaucomatous OA in our tertiary ophthalmology department between 2015 and 2020. We then examined how MME affected the thicknesses of the different retinal layers and the differences in demographic and clinical characteristics between those patients who developed MME and those who did not. A total of 643 eyes (429 patients) were included (mean age 45.9 ± 17.8 years, 52% female). MME developed in 95 (15%) eyes and across all etiologies of OA except for toxic/nutritional causes, but the prevalence of MME varied between the different etiologies. The development of MME was associated with thinning of the ganglion cell layer (11.0 vs. 9.6 μm; p = 0.001) and the retinal nerve fiber layer (10.1 vs. 9.15 μm; p = 0.024), with INL thickening in the 3- and 6-mm diameter areas of the central fovea. Patients developing MME had significantly worse distance best-corrected visual acuity than those not developing MME (0.62 vs. 0.38 logMAR; p = 0.002). Overall, the presence of MME in OA cannot be used to guide the diagnostic work-up of OA.

Scene Perception and Event Comprehension Theory (SPECT) posits that understanding picture stories depends upon a coordination of two processes: (1) integrating new information into the current event model that is coherent with it (i.e., mapping) and (2) segmenting experiences into distinct event models (i.e., shifting). In two experiments, we investigated competing hypotheses regarding how viewers coordinate the mapping process of bridging inference generation and the shifting process of event segmentation by manipulating the presence/absence of Bridging Action pictures (i.e., creating coherence gaps) in wordless picture stories. The Computational Effort Hypothesis says that experiencing a coherence gap prompts event segmentation and the additional computational effort to generate bridging inferences. Thus, it predicted a positive relationship between event segmentation and explanations when Bridging Actions were absent. Alternatively, the Coherence Gap Resolution Hypothesis says that experiencing a coherence gap prompt generating a bridging inference to close the gap, which obviates segmentation. Thus, it predicted a negative relationship between event segmentation and the production of explanations. Replicating prior work, viewers were more likely to segment and generate explanations when Bridging Action pictures were absent than when they were present. Crucially, the relationship between explanations and segmentation was negative when Bridging Action pictures were absent, consistent with the Coherence Gap Resolution Hypothesis. Unexpectedly, the relationship was positive when Bridging Actions were present. The results are consistent with SPECT's assumption that mapping and shifting processes are coordinated, but how they are coordinated depends upon the experience of a coherence gap.

This study aimed to evaluate the clinical information revealed after cycloplegia and assess how age and non-cycloplegic refractive status influence the classification of types of refractive error, as well as the relationship between age and cycloplegia-induced changes in the power of refractive errors. We analysed the records of 472 non-population-based ophthalmology practice patients aged 3-28 years (mean ± SD: 9.1 ± 4.6). Cycloplegia was induced with one drop of cyclopentolate 1% in each eye, and eye refraction was measured 30 ± 5 min later using an objective autorefractometer. Cycloplegia induced a clinically significant (≥0.50 D) hyperopic shift in the spherical equivalent of 60.2% of participants and a myopic shift in 1%, resulting in a 34.1% increase in the frequency of participants with hyperopia, while the frequency of those with myopia and emmetropia decreased by 5.5% and 23.3%, respectively. The average spherical equivalent difference (mean ± SD) induced by cycloplegia was 0.72 ± 0.73 D, with the highest difference observed in the 3-5 years age group (1.18 ± 0.85 D). The differences in astigmatism power (p = 0.84) and astigmatism axis (p = 0.97) between non-cycloplegic and cycloplegic conditions were not statistically significant.

A comparison of the accuracy of intraocular lens (IOL) power calculation formulae, including SRK/T, HofferQ, Holladay 1, Haigis, MM, Barrett Universal II (BUII), Emmetropia Verifying Optical (EVO), and AS-OCT ray tracing, was performed. One hundred eyes implanted with either the Rayone EMV RAO200E (Rayner Intraocular Lenses Limited, Worthing, UK) or the Artis Symbiose (Cristalens Industrie, Lannion, France) IOL were included. Biometry was obtained using IOLMaster 700 (Carl Zeiss Meditec AG, Jena, Germany) and MS-39 AS-OCT (CSO, Firenze, Italy). Mean (MAE) and median (MedAE) absolute errors and percentage of eyes within ±0.25D, ±0.50D, ±0.75D, and ±1.00D of the target were compared, with ±0.75D considered a key metric. The highest percentage within ±0.75D was found with MM (96%) followed by the Haigis (94%) for the enhanced monofocal IOL. SRK/T (94%) had the highest percentage within ±0.75D, followed by Holladay 1, MM, BUII, and ray tracing (all 90%) for the multifocal IOL. No statistically significant difference in MAE was found with both IOLs. EVO showed the lowest MAE for the enhanced monofocal and ray tracing for the multifocal IOL. EVO and ray tracing showed the lowest MedAE for the two respective IOLs. A similar performance with high accuracy across formulae was found. MM and ray tracing appear to have similar accuracy to the well-established formulae and displayed a high percentage of eyes within ±0.75D.

Computer vision is a powerful tool in medical image analysis, supporting the early detection and classification of eye diseases. Diabetic retinopathy (DR), a severe eye disease secondary to diabetes, accompanies several early signs of eye-threatening conditions, such as microaneurysms (MAs), hemorrhages (HEMOs), and exudates (EXs), which have been widely studied and targeted as objects to be detected by computer vision models. In this work, we tested the performances of the state-of-the-art YOLOv8 and YOLOv9 architectures on DR fundus features segmentation without coding experience or a programming background. We took one hundred DR images from the public MESSIDOR database, manually labelled and prepared them for pixel segmentation, and tested the detection abilities of different model variants. We increased the diversity of the training sample by data augmentation, including tiling, flipping, and rotating the fundus images. The proposed approaches reached an acceptable mean average precision (mAP) in detecting DR lesions such as MA, HEMO, and EX, as well as a hallmark of the posterior pole of the eye, such as the optic disc. We compared our results with related works in the literature involving different neural networks. Our results are promising, but far from being ready for implementation into clinical practice. Accurate lesion detection is mandatory to ensure early and correct diagnoses. Future works will investigate lesion detection further, especially MA segmentation, with improved extraction techniques, image pre-processing, and standardized datasets.

The aim of the study was to determine the normative data of the computerized DEM test for school-age children in Latvia. The study analyzed data on the performance (test execution time, duration, number of fixations, and number of errors) of 291 children while completing the computerized DEM test. Eye movement fixations were recorded with a Tobii Pro Fusion video-oculograph (250 Hz). According to the results of the study, the performance of the computerized DEM test is 77 %. For the study, 1 SD (one standard deviation) was chosen as a criterion for determining test norms. In the study, the norms of the computerized DEM test in Latvia were developed in class groups-from 1st to 6th grade (aged 7 to 12 years), the results were summarized in a table as the minimum performance values of the computerized DEM test.

Purpose: We aim to present a case of disseminated fusariosis that occurred in the setting of immunosuppression and presented with bilateral endogenous endophthalmitis, along with a literature review of Fusarium endophthalmitis, highlighting management strategies.

Observation: A 70-year-old male with acute myeloid leukemia who had recently undergone a bone marrow transplant noted bilateral floaters and decreased vision. He was found to have bilateral Fusarium endophthalmitis, with subsequent evidence of fungemia and fusariosis in his skin and joints. Despite aggressive local and systemic treatment, he succumbed to the disease. Endophthalmitis was initially stabilized with pars plana vitrectomy and intravitreal amphotericin and voriconazole until the patient transitioned to comfort measures. A review of 31 cases demonstrates that outcomes are poor and that the disease must be treated aggressively, often both systemically and surgically.

Conclusion: This case highlights the recalcitrance of Fusarium bacteremia and Fusarium endophthalmitis.

Previous research has shown that, like faces, words are processed either holistically or through the automatic representation of their parts combined. The automaticity assumed to underlie the holistic processing of words presupposes that individuals have a relatively low level of control over these processes. However, they may also be capable of learning from their environments whether processing words as a whole is the most efficient processing strategy-which would require at least some control over the corresponding processes. In fact, previous research supports this latter account in the context of the holistic processing of faces: when provided a task in which participants should ignore half of a stimuli (the irrelevant part) and pay selective attention to the other half (the target part), the participants become better at ignoring the irrelevant part when it is commonly misleading (i.e., this suggests a response that is different from that of the relevant part in the context of the task). In the present work, we extend these considerations to holistic word processing. Our results support a learned attentional account in the context of holistic word processing. When an irrelevant word part is systematically helpful for the judgment of a target word half, participants engage more in holistic processing (vs. when the irrelevant word half is misleading). This reflects an incidental statistical learning process in which individuals identify the irrelevant word half as either providing helpful or misleading information about the target half.

This study aims to explore the potential of a novel EYE ROLL device designed to facilitate guided vision relaxation exercises in an open space. A prospective study was performed on 89 participants who perform screenwork for at least four hours daily. All participants were randomly divided into three groups: a Control group with no exercising, a Manual group undertook manual vision relax ation exercises, and an Eyeroll group engaged in EYE ROLL device-assisted vision relaxation exercises. Each participant underwent three evaluations (an initial baseline assessment, a 4-week follow-up, and an 8-week follow-up) with four assessment tools: a comprehensive vision examination, an in-depth questionnaire, saccadic eye movement recordings, and objective accommodation measurements. There was a statistically significant decrease (35% and above) in complaint scores at the 4-week follow-up in both training groups. Although statistically insignificant, complaints continued to decrease after an 8-week period. No significant changes were observed in clinical or objective accommodative parameters. Some variation of visual functions was observed in all groups due to repeated measures. Vision relaxation exercises combined with proper vision ergonomics and working habits can reduce asthenopic complaints. The EYE ROLL device presents a promising tool for integrating these exercises into the working environment.

The purpose was to define the threshold of normal visual acuity (VA), mean monocular and binocular VA, and interocular difference in the uniform cohort of healthy four-year-old children. All the children were recruited from the Croatian National Registry of Early Amblyopia Detection database. LEA Symbols^® inline optotypes were used for VA testing at near and distance, binocularly and monocularly. The pass cut-off level was set to ≤0.1 logMAR. The final sample consisted of 58,712 four-year-old children. In total, 83.78% of the children had unremarkable results, and 16.22% of the children were referred to examination. Of those, 92% of the children were referred due to binocular, and 8% of the children due to monocular causes. The children referred due to binocular causes demonstrated a VA of 0.3 ± 0.24, while the children referred due to monocular causes 0.6 ± 0.21. The ROC curve analysis defined the uniform cut-off value for a normative VA of 0.78. We analyzed the largest uniform cohort of 58,712 children, and have determined normative data for binocular and monocular VA tested with gold standard logMAR chart in four-year-old children. The results presented here established no reasoning to further utilize historical protocols in testing VA in preschool children aged ≥ 4 years.