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Suspected clopidogrel-associated hepatitis in a cat. 一只猫疑似患有氯吡格雷相关性肝炎。
IF 0.7 Q3 VETERINARY SCIENCES Pub Date : 2024-11-06 eCollection Date: 2024-07-01 DOI: 10.1177/20551169241278408
Astrid L Kamp, Washma Yousofzai, Hans S Kooistra, Giorgia Santarelli, Ingeborg M van Geijlswijk

Case summary: Acute hepatitis and liver damage are rare adverse effects of clopidogrel in humans. In veterinary medicine, clopidogrel is mainly prescribed in the treatment of feline patients with cardiomyopathies. Little is known regarding the safety and adverse effects of clopidogrel in this group of patients. The limited number of studies scarcely report adverse effects. In this case report, a 6-year-old male castrated crossbred cat with the hypertrophic cardiomyopathy phenotype had signs of acute hepatitis after 5 weeks of clopidogrel treatment.

Relevance and novel information: Evaluation of the case and review of the literature indicate that acute hepatitis might be a potential adverse effect of clopidogrel in feline patients. Therefore, hepatotoxicity should be taken into consideration when a feline patient shows clinical deterioration after the use of clopidogrel.

病例摘要:急性肝炎和肝损伤是氯吡格雷对人类的罕见不良反应。在兽医领域,氯吡格雷主要用于治疗患有心肌病的猫科动物患者。人们对氯吡格雷在这类患者中的安全性和不良反应知之甚少。数量有限的研究也很少报告其不良反应。在本病例报告中,一只患有肥厚型心肌病表型的 6 岁雄性阉割杂交猫在接受氯吡格雷治疗 5 周后出现急性肝炎症状:对该病例的评估和文献综述表明,急性肝炎可能是氯吡格雷对猫科动物患者的潜在不良反应。因此,当猫科动物患者在使用氯吡格雷后出现临床症状恶化时,应将肝毒性考虑在内。
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引用次数: 0
Use of intranasal povidone-iodine packing in the management of infectious rhinosinusitis in three cats. 使用聚维酮碘鼻内填料治疗三只猫的传染性鼻炎。
IF 0.7 Q3 VETERINARY SCIENCES Pub Date : 2024-11-05 eCollection Date: 2024-07-01 DOI: 10.1177/20551169241275303
Paul J Sorrentino, Sandra L MacArthur

Case series summary: Described are three cats diagnosed with rhinosinusitis secondary to Mycobacterium bouchedurhonense, Aspergillus species and Alternaria species, respectively. Medical records were retrospectively reviewed to identify cats with decreased nasal airflow and mucopurulent discharge that failed to improve on antibiotic therapy of 3 months or longer duration. Surgical debridement was followed by nasal packing using 5% povidone-iodine saturated umbilical tape, which was replaced at 24 h postoperatively. At 48 h postoperatively, the rhinotomy site was closed. Systemic therapy continued in the postoperative period. All cases were minimally responsive to previous medical management. History, signalment, clinical signs, diagnostic findings, treatment, and short- and long-term outcomes were retrieved. All cats were middle-aged with outdoor access and had clinical signs that commenced during the summer months. CT revealed turbinate destruction and soft tissue densities within the nasal passages. The otic apparatuses and calvaria were intact in all cats before surgery. A repeat CT examination revealed an improvement of the proliferative tissue identified in preoperative imaging in all cases. All cats achieved successful interruption of nasal discharge and restoration of nasal airflow with follow-up times of up to 16 months postoperatively.

Relevance and novel information: To the authors' knowledge, this is the first report of the use of intranasal povidone-iodine packing in cats for the management of infectious rhinosinusitis. Surgical debridement and intranasal packing in addition to systemic therapy were successful in restoring nasal airflow and resolving nasal discharge in all cats with long-term follow-up.

病例系列摘要:描述了三只分别被诊断为继发于布氏分枝杆菌、曲霉菌和交替孢霉属的鼻炎的猫。我们对病历进行了回顾性审查,以确定哪些猫的鼻腔气流减弱并伴有粘液脓性分泌物,且在接受 3 个月或更长时间的抗生素治疗后病情仍未好转。手术清创后使用 5%聚维酮碘饱和脐带进行鼻腔填塞,术后 24 小时更换脐带。术后 48 小时,关闭鼻腔切开部位。术后继续进行全身治疗。所有病例均对之前的药物治疗反应轻微。对病史、信号、临床症状、诊断结果、治疗以及短期和长期疗效进行了检索。所有病猫均为中年,可在户外活动,临床症状始于夏季。CT 显示鼻甲受损,鼻腔内软组织密集。手术前,所有猫咪的耳道和颅骨都完好无损。复查 CT 发现,所有病例术前成像中发现的增生组织都有所改善。术后随访时间长达 16 个月,所有猫都成功阻断了鼻腔分泌物并恢复了鼻腔气流:据作者所知,这是首次报道在猫体内使用聚维酮碘填料治疗感染性鼻炎。除全身治疗外,手术清创和鼻内填塞成功地恢复了所有猫的鼻腔气流,并在长期随访中解决了猫流鼻涕的问题。
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引用次数: 0
Short-term severe polyuria responsive to vasopressin after hypoglycaemia and hypotension in a domestic shorthair cat. 一只家养短毛猫在低血糖和低血压后出现对血管加压素有反应的短期严重多尿。
IF 0.7 Q3 VETERINARY SCIENCES Pub Date : 2024-11-04 eCollection Date: 2024-07-01 DOI: 10.1177/20551169241283294
Federica Porcarelli, Carla Asorey Blazquez, Ferran Valls Sanchez, Elena Scarpante, Giacomo Stanzani

Case summary: An 8-month-old male neutered domestic shorthair cat presented for acute vomiting. Abdominal ultrasound examination revealed a jejunal foreign body, which was removed via enterotomy. Preoperatively, the patient was hypoglycaemic and, intraoperatively, a dopamine infusion was required to maintain a mean arterial pressure >60 mmHg. Despite glucose supplementation, the cat remained severely hypoglycaemic on recovery. Within 24 h postoperatively, despite euglycaemia and normalisation of the cardiovascular status, the patient developed progressive polyuria (up to 14 ml/kg/h). This was associated with neurological signs suggestive of diffuse brain disease, and absence of azotaemia or signs of overhydration. During the first 4 days of hospitalisation, any attempts to decrease intravenous fluid therapy were associated with hypotension, weight loss and clinical dehydration. Urine specific gravity (USG) during this time was in the range of 1.005-1.010 and failed to increase during fluid challenges. A presumptive diagnosis of central diabetes insipidus was made, and desmopressin (1 µg/cat SC) was administered on day 5 of hospitalisation. Consequently, the cat's urinary output decreased and his weight increased within 4 h. The patient required a total of four doses of desmopressin during hospitalisation, but no further doses since discharge. Urinary output on discharge was 3 ml/kg/h. Three months later, the cat's neurological signs and polyuria had completely resolved, and the USG was >1.050.

Relevance and novel information: In this case, a presumptive diagnosis of central diabetes insipidus was supported by clinical progression, neurological signs and the response to desmopressin. To our knowledge, this is the first report of reversible diabetes insipidus after diffuse brain injury secondary to hypotension and hypoglycaemia.

病例摘要:一只 8 个月大的雄性阉割短毛猫因急性呕吐就诊。腹部超声波检查发现空肠异物,通过肠切开术将异物取出。术前患者血糖过低,术中需要输注多巴胺以维持平均动脉压大于 60 mmHg。尽管补充了葡萄糖,但猫咪恢复后仍然严重低血糖。术后 24 小时内,尽管出现了优格血症,心血管状况也恢复正常,但患者仍出现了进行性多尿(高达 14 毫升/千克/小时)。这与提示弥漫性脑部疾病的神经系统体征有关,但没有氮质血症或过度脱水的体征。在住院的头四天里,任何减少静脉输液治疗的尝试都会导致低血压、体重下降和临床脱水。在此期间,尿比重(USG)在 1.005-1.010 之间,在输液挑战中也没有增加。推测诊断为中枢性糖尿病,并在住院第 5 天给它注射了去氨加压素(1 µg/ 猫 SC)。结果,猫咪的尿量在 4 小时内减少了,体重也增加了。患者在住院期间总共需要注射四次去氨加压素,但出院后就没有再注射过。出院时的尿量为 3 毫升/千克/小时。三个月后,猫的神经症状和多尿症状完全消失,USG>1.050:在本病例中,临床进展、神经症状和对去氨加压素的反应支持了中枢性糖尿病的推定诊断。据我们所知,这是首例弥漫性脑损伤后继发低血压和低血糖导致的可逆性糖尿病。
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引用次数: 0
Tubulotrabecular adenocarcinoma of the nasopharynx operated by transoral and transpalatal approach in a cat. 在一只猫身上通过经口和经腭入路手术切除的鼻咽管状腺癌。
IF 0.7 Q3 VETERINARY SCIENCES Pub Date : 2024-10-24 eCollection Date: 2024-07-01 DOI: 10.1177/20551169241283542
Estelle Ferenczi, Chantal Ragetly

Case summary: A 10-year-old castrated male crossbreed Birman cat was presented for respiratory difficulties, nasal discharge, dysphagia and wheezing. An obstructive nasopharyngeal mass invading the caudoventral nasal cavity and the left sphenoid sinus was observed on a CT scan. Surgical treatment via a ventral rhinotomy and curettage was performed. Histopathology revealed an adenocarcinoma with tubulotrabecular architecture. The cat's clinical signs significantly improved postoperatively. After 10 months, a recurrence was documented and a second surgical procedure was performed that allowed the patient to live an additional 6 months without clinical signs and an overall survival time of 19 months after first presentation.

Relevance and novel information: This case report describes a nasopharyngeal adenocarcinoma treated by ventral rhinotomy in a cat. To our knowledge, there is only one other report describing this surgery on a nasal adenocarcinoma in a cat. The tomodensitometric, endoscopic and unusual histological appearance of the mass are reported. The prognosis after surgical removal of nasal adenocarcinomas in cats is only sparsely documented. This case demonstrates that ventral rhinotomy might be considered if first-line treatment is declined.

病例摘要:一只 10 岁的雄性阉割杂交比尔曼猫因呼吸困难、流鼻涕、吞咽困难和喘息而就诊。CT 扫描发现,鼻咽部有一个阻塞性肿块,侵入鼻腔尾腹部和左侧蝶窦。患者接受了鼻腔腹侧切开术和刮除术。组织病理学检查显示,这是一种具有管状结构的腺癌。术后猫咪的临床症状明显好转。10 个月后,患者的病情复发,于是进行了第二次手术,术后患者又存活了 6 个月,没有出现任何临床症状,总存活时间为 19 个月:本病例报告描述了在一只猫身上通过鼻腹部切除术治疗鼻咽腺癌的情况。据我们所知,目前仅有一份报告描述了猫鼻咽腺癌的这种手术。报告中介绍了肿块的断层密度测量、内窥镜和不寻常的组织学外观。关于猫鼻腔腺癌手术切除后的预后,文献记载很少。本病例表明,如果拒绝一线治疗,可以考虑进行鼻腹腔手术。
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引用次数: 0
Infraspinatus muscle necrosis in a cat with primary hyperaldosteronism. 一只患有原发性高醛固酮症的猫的冈下肌坏死。
IF 0.7 Q3 VETERINARY SCIENCES Pub Date : 2024-10-17 eCollection Date: 2024-07-01 DOI: 10.1177/20551169241282737
Go Otani, Hiroshi Ohta

Case summary: Persistent and progressive weakness secondary to hypokalaemia, that is, hypokalaemic polymyopathy, is one of the most common clinical signs of primary hyperaldosteronism (PHA). Herein, we report a case of PHA with infraspinatus muscle necrosis. A 5-year-old castrated male domestic shorthair cat presented with a history of polyuria and polydipsia, decreased activity, staggering gait, difficulty in jumping and inward rotation of both forelimbs. Blood examination revealed hypokalaemia, increased serum creatinine kinase activity and high serum aldosterone concentration. Abdominal ultrasonography and CT revealed an enlarged right adrenal gland. Post-contrast thoracic CT showed peripheral contrast enhancement and a non-enhanced centre in the bilateral infraspinatus muscles. From the day of initial presentation, the cat was started on oral potassium replacement therapy. On day 17, the right adrenal gland was surgically resected and the left infraspinatus muscle was biopsied. Histopathological examination confirmed the presence of an adrenocortical adenoma in the right adrenal gland and necrosis of the muscle fibres in the left infraspinatus muscle. On day 29, all clinical signs had disappeared, and the serum potassium concentration, creatinine kinase activity and aldosterone concentration had normalised. On day 57, atrophy of the bilateral infraspinatus muscles was noted, but there was no evidence of any posture or gait abnormalities.

Relevance and novel information: To the authors' knowledge, this is the first report of possible infraspinatus muscle necrosis in a cat with PHA. It is also possible that the infrinatus muscle necrosis with hypokalaemic polymyopathy secondary to PHA was caused by compartment syndrome in the cat described here.

病例摘要:继发于低钾血症的持续性和进行性乏力,即低钾血症性多肌病,是原发性高醛固酮血症(PHA)最常见的临床表现之一。在此,我们报告了一例伴有冈下肌坏死的 PHA 病例。一只 5 岁的阉割雄性短毛猫出现多尿、多饮、活动减少、步态蹒跚、跳跃困难和双前肢内旋。血液检查显示该猫患有低钾血症,血清肌酸激酶活性升高,血清醛固酮浓度较高。腹部超声波和 CT 显示右侧肾上腺肿大。对比后胸部 CT 显示双侧冈下肌周围对比增强,中心无增强。从最初出现的那天起,猫就开始接受口服钾替代治疗。第 17 天,手术切除了右侧肾上腺,并对左侧冈下肌进行了活组织检查。组织病理学检查证实,右侧肾上腺存在肾上腺皮质腺瘤,左侧冈下肌肌纤维坏死。第 29 天,所有临床症状消失,血清钾浓度、肌酸激酶活性和醛固酮浓度恢复正常。第 57 天,发现双侧冈下肌萎缩,但没有任何姿势或步态异常的迹象:据作者所知,这是第一份关于患有 PHA 的猫可能出现冈下肌坏死的报告。在本报告中描述的这只猫中,冈下肌坏死和继发于 PHA 的低钾血症性多肌病也可能是由室间综合征引起的。
{"title":"Infraspinatus muscle necrosis in a cat with primary hyperaldosteronism.","authors":"Go Otani, Hiroshi Ohta","doi":"10.1177/20551169241282737","DOIUrl":"10.1177/20551169241282737","url":null,"abstract":"<p><strong>Case summary: </strong>Persistent and progressive weakness secondary to hypokalaemia, that is, hypokalaemic polymyopathy, is one of the most common clinical signs of primary hyperaldosteronism (PHA). Herein, we report a case of PHA with infraspinatus muscle necrosis. A 5-year-old castrated male domestic shorthair cat presented with a history of polyuria and polydipsia, decreased activity, staggering gait, difficulty in jumping and inward rotation of both forelimbs. Blood examination revealed hypokalaemia, increased serum creatinine kinase activity and high serum aldosterone concentration. Abdominal ultrasonography and CT revealed an enlarged right adrenal gland. Post-contrast thoracic CT showed peripheral contrast enhancement and a non-enhanced centre in the bilateral infraspinatus muscles. From the day of initial presentation, the cat was started on oral potassium replacement therapy. On day 17, the right adrenal gland was surgically resected and the left infraspinatus muscle was biopsied. Histopathological examination confirmed the presence of an adrenocortical adenoma in the right adrenal gland and necrosis of the muscle fibres in the left infraspinatus muscle. On day 29, all clinical signs had disappeared, and the serum potassium concentration, creatinine kinase activity and aldosterone concentration had normalised. On day 57, atrophy of the bilateral infraspinatus muscles was noted, but there was no evidence of any posture or gait abnormalities.</p><p><strong>Relevance and novel information: </strong>To the authors' knowledge, this is the first report of possible infraspinatus muscle necrosis in a cat with PHA. It is also possible that the infrinatus muscle necrosis with hypokalaemic polymyopathy secondary to PHA was caused by compartment syndrome in the cat described here.</p>","PeriodicalId":36588,"journal":{"name":"Journal of Feline Medicine and Surgery Open Reports","volume":"10 2","pages":"20551169241282737"},"PeriodicalIF":0.7,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11487503/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142476730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modified circumferential preputioplasty using a Keyes biopsy punch for treatment of type I phimosis in two kittens. 使用 Keyes 活检打孔器进行改良的包皮环切术,治疗两只小猫的 I 型包皮龟头炎。
IF 0.7 Q3 VETERINARY SCIENCES Pub Date : 2024-10-13 eCollection Date: 2024-07-01 DOI: 10.1177/20551169241277068
Beatrice Hertel, Victoria Roberts, Claire Deroy-Bordenave, Jessica Adamany, Rosario Vallefuoco

Case series summary: Medical records of two kittens diagnosed with type I phimosis were reviewed. Clinical signs on presentation, investigations, description of the surgical technique, and short- and long-term follow-up were reported. Type I phimosis was diagnosed in both kittens based on the clinical, radiographic and surgical exploration findings. Modified circumferential preputioplasty using 4 and 6 mm Keyes biopsy punches was performed by the same surgeon in each case. The biopsy punch was centred over the existing narrowed preputial orifice and rotated clockwise and anticlockwise to obtain a sharp circumferential cut through the skin and submucosa of predictable diameter. The underlying mucosa was resected with micro curved scissors and mucocutaneous apposition was achieved with simple interrupted sutures placed circumferentially. Minor protrusion of the tip of the penis was recorded in the short-term follow-up (2 weeks) but resolved on the long-term follow-up (10 and 72 months). No evidence of urinary tract infection, strictures or clinical signs associated with phimosis were recorded at long-term follow-up.

Relevance and novel information: This short case series describes the surgical correction of type I phimosis by circumferential preputioplasty implemented using a Keyes biopsy punch in two kittens. The technique described in this case series can be considered alongside other reported surgical techniques, and appears to provide a reliable, rapid and accurate removal of preputial skin in the two reported cases.

病例系列摘要:本文回顾了两只被诊断为 I 型包皮龟头炎的小猫的医疗记录。报告了发病时的临床症状、检查结果、手术技术描述以及短期和长期随访情况。根据临床、影像学和手术探查结果,两只小猫均被诊断为 I 型包皮龟头炎。每个病例都由同一名外科医生使用 4 毫米和 6 毫米 Keyes 活检穿刺针进行了改良的包皮环切术。活检穿刺器以现有狭窄的阴道前口为中心,顺时针和逆时针旋转,在皮肤和粘膜下形成直径可预测的锐利环形切口。用微型弯剪切除下层粘膜,然后用简单的间断缝合线沿周向缝合粘膜和皮肤。在短期随访(2 周)中记录到阴茎头有轻微突出,但在长期随访(10 个月和 72 个月)中症状消失。长期随访中未发现尿路感染、狭窄或与包皮过长相关的临床症状:这组简短的病例描述了使用 Keyes 活检打孔器对两只小猫进行包皮环切术矫正 I 型包皮过长。本病例系列中描述的技术可与其他已报道的手术技术一并考虑,在已报道的两个病例中,该技术似乎能可靠、快速、准确地切除包皮。
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引用次数: 0
Hypokalaemic myopathy associated with iatrogenic hypercorticism in a cat. 一只猫因先天性皮质功能亢进引起的低钾血症性肌病。
IF 0.7 Q3 VETERINARY SCIENCES Pub Date : 2024-10-10 eCollection Date: 2024-07-01 DOI: 10.1177/20551169241273571
Annamaria Tiozzo Ambrosi, Giorgia Lovato, Laura Pintore, Carolina Callegari, Alice Tamborini

Case summary: A 12-year-old castrated male domestic shorthair cat was referred for investigation of lethargy, hindlimb weakness with plantigrade stance and ventroflexion of the neck. The cat was fed a balanced diet and had received methylprednisolone acetate at a dose of 20 mg intramuscularly every 6 months for 6 years. On blood work, severe hypokalaemia and marked elevation of muscle enzymes were noticeable. The findings were suggestive of hypokalaemic myopathy. Urine fractional excretion of potassium (FEk) was moderately high (9.04%), and serum aldosterone was below the reference interval. An adrenocorticotropic hormone (ACTH) stimulation test was compatible with adrenal suppression. Upon hospitalisation, the patient was given intravenous (IV) Ringer lactate solution supplemented with potassium chloride and oral potassium citrate. The serum potassium concentration normalised by the fifth day of hospitalisation; therefore, IV potassium supplementation was suspended. The cat was discharged with oral potassium and the dose was gradually reduced over time. After 4 months, the cat was clinically normal; the serum potassium concentration remained within the normal range and the adrenal glands showed some response to ACTH stimulation. Potassium supplementation was therefore discontinued. One month later, the serum potassium concentration was still within normal limits and at the time of writing (7 months after presentation), no clinical signs had reoccurred.

Relevance and novel information: This report describes a case of hypokalaemic myopathy associated with iatrogenic hypercorticism in a cat. This condition was successfully treated with supplementation of potassium and a complete clinical remission was achieved within 4 months.

病例摘要:一只 12 岁的阉割雄性家养短毛猫因嗜睡、后肢无力、匍匐和颈部外翻而被转诊就医。该猫饮食均衡,6 年来一直服用醋酸甲泼尼龙,每 6 个月肌肉注射一次,剂量为 20 毫克。血液检查结果显示,该猫患有严重的低钾血症,肌酶明显升高。这些结果提示患者患有低血钾性肌病。尿钾排泄率(FEk)中等偏高(9.04%),血清醛固酮低于参考区间。促肾上腺皮质激素(ACTH)刺激试验与肾上腺抑制相符。入院后,患者接受了补充氯化钾的静脉注射(IV)林格乳酸盐溶液和口服枸橼酸钾。住院第五天,血清钾浓度恢复正常,因此暂停了静脉补钾。猫咪出院时口服了钾,并随着时间的推移逐渐减少了剂量。4 个月后,猫咪的临床症状恢复正常;血清钾浓度仍在正常范围内,肾上腺对促肾上腺皮质激素刺激也有一些反应。因此,钾补充剂被停止使用。一个月后,猫的血清钾浓度仍在正常范围内,在撰写本报告时(发病 7 个月后),临床症状没有再次出现:本报告描述了一例与先天性皮质功能亢进有关的低血钾性肌病。通过补充钾成功治疗了这种病症,并在 4 个月内实现了临床症状的完全缓解。
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引用次数: 0
First description of oesophageal melanoma in a cat and palliative treatment by endoscopic argon plasma coagulation laser. 首次描述猫的食道黑色素瘤并通过内窥镜氩等离子凝固激光进行姑息治疗。
IF 0.7 Q3 VETERINARY SCIENCES Pub Date : 2024-10-07 eCollection Date: 2024-07-01 DOI: 10.1177/20551169241277076
Riccardo Ferriani, Teresa Bruna Pagano, Enrico Bottero

Case summary: An 11-year-old castrated male domestic shorthair cat presented with chronic regurgitation and weight loss. Despite a 2-month history of weight loss, regurgitation intensified over 4 weeks, occurring with every food intake, even on a semi-liquid diet. Physical examination revealed thinness and dehydration, and a focal oval mass was noted in the middle mediastinum on thoracic radiography. Oesophagoscopy identified a 6 cm neoformation almost completely obstructing the oesophageal lumen. Biopsies were taken and histopathology, positivity to melanoma triple cocktail and PNL-2 by immunohistochemistry led to the diagnosis of melanocytic neoplasm. Palliative debulking with argon plasma coagulation (APC) was performed, significantly improving the cat's quality of life for 2 months. The cat survived for 107 days after diagnosis.

Relevance and novel information: This case report describes the first report of melanocytic neoplasia originating from the oesophageal mucosa in a cat. In cats, melanomas outside the eyes are exceedingly rare and oesophageal neoplasms are exceptionally rare in veterinary medicine, particularly melanomas. The diagnosis relied on positive immunohistochemistry markers aligning with previous research. Treatment with APC emerged as a novel, potentially palliative approach, successfully alleviating regurgitation for 3 months. This underscores APC's potential in feline oesophageal neoplasia palliative care, which deserves further investigation in a broader feline cohort to confirm its efficacy. Overall, this report provides valuable insights into the diagnosis and treatment of oesophageal melanoma in cats.

病例摘要:一只 11 岁的阉割雄性短毛猫因长期反胃和体重减轻而就诊。尽管体重减轻已有 2 个月的历史,但反胃症状在 4 周内加剧,每次进食都会发生反胃,即使进食半流质食物也是如此。体格检查显示患者消瘦、脱水,胸部放射线检查发现中纵隔有一局灶性椭圆形肿块。食管镜检查发现,一个 6 厘米长的新生畸形几乎完全阻塞了食管腔。经过活检和组织病理学检查,黑色素瘤三联鸡尾酒和 PNL-2 免疫组化呈阳性,诊断为黑色素细胞瘤。采用氩等离子凝固术(APC)进行了姑息性剥离,显著改善了猫咪两个月的生活质量。该猫在确诊后存活了 107 天:本病例报告首次报道了猫食道粘膜黑色素细胞瘤。在猫科动物中,眼睛以外的黑色素瘤极为罕见,而食道肿瘤在兽医学中也极为罕见,尤其是黑色素瘤。诊断依据的是与以往研究一致的阳性免疫组化标记。使用 APC 治疗是一种新颖的、潜在的缓解方法,可成功缓解反流 3 个月。这凸显了 APC 在猫食道肿瘤姑息治疗中的潜力,值得在更广泛的猫群中进行进一步研究,以确认其疗效。总之,本报告为猫食道黑色素瘤的诊断和治疗提供了宝贵的见解。
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引用次数: 0
Successful correction of flat-chested kitten syndrome in two littermate kittens. 成功矫正了两只同窝幼猫的平胸症。
IF 0.7 Q3 VETERINARY SCIENCES Pub Date : 2024-09-26 eCollection Date: 2024-07-01 DOI: 10.1177/20551169241273665
Jasmine Fusi, Mara Bagardi, Jessica Bassi, Francesco Ferrari, Maria Cristina Veronesi

Case summary Two 18-day-old domestic shorthair kittens presented with dyspnoea, mild cyanosis, heart murmur, lung pattern, abnormal crawling and a marked dorsoventral flattening of the thorax. Deformity of the thoracic wall without pectus excavatum was diagnosed. Cardboard corsets tailored to each kitten were applied. This gave immediate respiratory relief, easing distress and pain. After 10 days, clinical and radiographic monitoring revealed normalisation of the shape of the chest wall with an improvement in general condition. At 6 months of age, clinical examination showed normal growth and development of both kittens, with a normal thoracic profile and shape also seen on radiographs. Relevance and novel information Data about flat-chested kitten syndrome and its aetiopathogenesis, treatment and outcome are scarce, but there is significant experience among breeders that is shared through online communities. High mortality rates are reported. The use of a cardboard splint appears to be novel in the published literature; in this case report, it proved to be a rapid and easy solution. For this reason, cardboard splints could be considered as a first approach for the clinical management of flat-chested kitten syndrome.

病例摘要 两只 18 天大的家养短毛猫出现呼吸困难、轻度发绀、心脏杂音、肺纹、异常爬行和胸廓明显背腹扁平。诊断结果为胸壁畸形,但没有开胸症。为每只小猫量身定制了纸板束腹带。这立即缓解了呼吸困难和疼痛。10 天后,临床和射线监测显示胸壁形状恢复正常,总体状况有所改善。6 个月大时,临床检查显示两只小猫的生长发育正常,X 光片也显示胸廓和形状正常。相关性和新信息 有关平胸幼猫综合症及其发病机制、治疗和结果的数据很少,但饲养者通过网络社区分享了大量经验。据报道,该病的死亡率很高。在已发表的文献中,使用纸板夹板似乎是一种新方法;在本病例报告中,事实证明这种方法既快速又简单。因此,纸板夹板可作为临床治疗扁胸幼猫综合症的首选方法。
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引用次数: 0
Lidocaine-saturated cotton tip applicator used for laryngeal desensitization resulting in an iatrogenic tracheobronchial foreign body in two cats. 用于喉部脱敏的利多卡因饱和棉尖涂抹器导致两只猫出现气管支气管异物。
IF 0.7 Q3 VETERINARY SCIENCES Pub Date : 2024-09-19 eCollection Date: 2024-07-01 DOI: 10.1177/20551169241273680
Kamila A Correa, Emily P Wheeler, Victoria S Miller, Meredith E 't Hoen

Case series summary: Two cats were referred to a veterinary teaching hospital with a cotton tip applicator (CTA) tracheobronchial foreign body (FB) after induction of anesthesia for an elective dental cleaning. In both cases, a lidocaine-saturated CTA, utilized to desensitize the larynx before endotracheal (ET) intubation, broke when introduced into the oropharynx and was subsequently aspirated into the tracheobronchial tree. Both CTAs were successfully removed bronchoscopically, and the cats survived with no short- or long-term complications noted.

Relevance and novel information: Utilizing a lidocaine-saturated CTA to facilitate ET intubation in cats is not well described, and information on the relative risks and benefits of this specific method for laryngeal desensitization is lacking. This retrospective case series is the first to describe a complication of this technique and successful treatment. These cases highlight the risk inherent to using a CTA to desensitize the feline larynx.

病例系列摘要:两只猫在进行选择性洗牙的麻醉诱导后,因发现气管支气管异物(FB)而被转诊到一家兽医教学医院。在这两个病例中,气管插管(ET)前用于喉部脱敏的利多卡因饱和 CTA 在进入口咽部时破裂,随后被吸入气管支气管树。两枚 CTA 均在支气管镜下成功取出,猫咪存活下来,未发现短期或长期并发症:利用利多卡因饱和的 CTA 为猫进行 ET 插管的描述并不详尽,也缺乏有关这种喉部脱敏特定方法的相对风险和益处的信息。本回顾性系列病例首次描述了这种技术的并发症和成功治疗。这些病例强调了使用 CTA 对猫喉部脱敏的固有风险。
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引用次数: 0
期刊
Journal of Feline Medicine and Surgery Open Reports
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