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Least square-support vector machine based brain tumor classification system with multi model texture features 基于最小平方支持向量机的脑肿瘤分类系统与多模型纹理特征
IF 1.4 Q3 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2023-12-06 DOI: 10.3389/fams.2023.1324054
F. Khan, Yonis Gulzar, Shahnawaz Ayoub, Muneer Majid, Mohammad Shuaib Mir, Arjumand Bano Soomro
Radiologists confront formidable challenges when confronted with the intricate task of classifying brain tumors through the analysis of MRI images. Our forthcoming manuscript introduces an innovative and highly effective methodology that capitalizes on the capabilities of Least Squares Support Vector Machines (LS-SVM) in tandem with the rich insights drawn from Multi-Scale Morphological Texture Features (MMTF) extracted from T1-weighted MR images. Our methodology underwent meticulous evaluation on a substantial dataset encompassing 139 cases, consisting of 119 cases of aberrant tumors and 20 cases of normal brain images. The outcomes we achieved are nothing short of extraordinary. Our LS-SVM-based approach vastly outperforms competing classifiers, demonstrating its dominance with an exceptional accuracy rate of 98.97%. This represents a substantial 3.97% improvement over alternative methods, accompanied by a notable 2.48% enhancement in Sensitivity and a substantial 10% increase in Specificity. These results conclusively surpass the performance of traditional classifiers such as Support Vector Machines (SVM), Radial Basis Function (RBF), and Artificial Neural Networks (ANN) in terms of classification accuracy. The outstanding performance of our model in the realm of brain tumor diagnosis signifies a substantial leap forward in the field, holding the promise of delivering more precise and dependable tools for radiologists and healthcare professionals in their pivotal role of identifying and classifying brain tumors using MRI imaging techniques.
放射科医生在面对通过分析核磁共振成像图像对脑肿瘤进行分类的复杂任务时,面临着巨大的挑战。我们即将出版的手稿介绍了一种创新和高效的方法,该方法利用了最小二乘支持向量机(LS-SVM)的能力,以及从t1加权MR图像中提取的多尺度形态纹理特征(MMTF)中获得的丰富见解。我们的方法对包含139例病例的大量数据集进行了细致的评估,其中包括119例异常肿瘤和20例正常脑图像。我们取得的成果是非凡的。我们基于ls - svm的方法大大优于竞争对手的分类器,以98.97%的超高准确率证明了它的优势。这比其他方法提高了3.97%,灵敏度提高了2.48%,特异性提高了10%。这些结果在分类精度方面明显优于传统分类器,如支持向量机(SVM)、径向基函数(RBF)和人工神经网络(ANN)。我们的模型在脑肿瘤诊断领域的杰出表现标志着该领域的重大飞跃,为放射科医生和医疗保健专业人员提供更精确和可靠的工具,帮助他们在使用MRI成像技术识别和分类脑肿瘤的关键作用。
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引用次数: 0
Directionally weakened diffusion for image segmentation using active contours 利用主动轮廓进行定向弱化扩散图像分割
IF 1.4 Q3 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2023-12-05 DOI: 10.3389/fams.2023.1275588
Zhitao Wang, Nana Li, Quan Zhang, Jin Wei, Lei Zhang, Yuanquan Wang
The active contour model, also known as the snake model, is an elegant approach for image segmentation and motion tracking. The gradient vector flow (GVF) is an effective external force for active contours. However, the GVF model is based on isotropic diffusion and does not take the image structure into account. The GVF snake cannot converge to very deep concavities and blob-like concavities and fails to preserve weak edges neighboring strong ones. To address these limitations, we first propose the directionally weakened diffusion (DWD), which is anisotropic by incorporating the image structure in a subtle way. Using the DWD, a novel external force called directionally weakened gradient vector flow (DWGVF) is proposed for active contours. In addition, two spatiotemporally varying weights are employed to make the DWGVF robust to noise. The DWGVF snake has been assessed on both synthetic and real images. Experimental results show that the DWGVF snake provides much better results in terms of noise robustness, weak edge preserving, and convergence of various concavities when compared with the well-known GVF, the generalized GVF (GGVF) snake.
活动轮廓模型,也称为蛇形模型,是一种用于图像分割和运动跟踪的优雅方法。梯度矢量流(GVF)是活动轮廓的有效外力。然而,梯度矢量流场模型是基于各向同性扩散的,没有考虑图像的结构。GVF蛇形不能收敛到非常深的凹坑和斑点状凹坑,并且不能保留强边缘附近的弱边缘。为了解决这些限制,我们首先提出了定向减弱扩散(DWD),它是通过微妙的方式结合图像结构的各向异性。在此基础上,提出了一种针对活动轮廓线的定向减弱梯度矢量流(DWGVF)外力。此外,采用两个时空变化权值,增强了DWGVF对噪声的鲁棒性。DWGVF蛇已经在合成和真实图像上进行了评估。实验结果表明,与通用GVF (GGVF)相比,DWGVF snake在噪声鲁棒性、弱边缘保持性和各种凹点收敛性方面都有较好的效果。
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引用次数: 0
Portfolio optimization and valuation capability of multi-factor models: an observational evidence from Dhaka stock exchange 多因素模型的投资组合优化和估值能力:来自达卡证券交易所的观察证据
IF 1.4 Q3 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2023-12-05 DOI: 10.3389/fams.2023.1271485
Md. Ahsan Kabir, Liping Yu, Sanjoy Kumar Sarker, Md. Nahiduzzaman, Tanmay Borman
The main goal of this study is to examine the return explanation strengths of the Carhart four-factor, the Fama–French three-factor, and the single-factor models in the context of the Bangladeshi stock market. We, therefore, reveal the risk-adjusted returns, test the valuation capability of multi-factor models, and estimate optimal portfolio weights of stocks listed in DSE under the DSE30 index. Our findings demonstrate that large capitalization firms that have low or medium book-to-market (B/M) ratios produce more concentrated returns than their counterparts, resulting in greater earnings per unit of total, systematic, and downside risks. Furthermore, we discover that each factorial value has an impressive capacity to explain the market excess returns; however, the influence of factor values on the cross-section of stock returns is somewhat contradictory. In particular, the momentum factor is unable to describe the cross-section excess returns, whereas the risk premium, size, and value factors have a significant impact on the cross-section excess returns. Finally, we find that a large-cap firm with a low B/M ratio is suitable for risk-seeking investors; in contrast, a small-cap firm with a low B/M ratio is appropriate for lower risk tolerance investors. Moreover, our empirical outcomes have noteworthy implications for private companies, investors, and policymakers.
本研究的主要目的是检验Carhart四因素模型、Fama-French三因素模型和单因素模型在孟加拉国股票市场背景下的收益解释优势。因此,我们揭示了风险调整后的收益,检验了多因素模型的估值能力,并估计了DSE30指数下DSE上市股票的最优投资组合权重。我们的研究结果表明,具有低或中等账面市值比(B/M)的大型资本公司比其同行产生更集中的回报,从而导致总、系统和下行风险的单位收益更高。此外,我们发现每个阶乘值都具有令人印象深刻的解释市场超额收益的能力;然而,因子值对股票收益横截面的影响是有些矛盾的。其中动量因子无法描述横截面超额收益,而风险溢价、规模和价值因子对横截面超额收益有显著影响。最后,我们发现低账面价值比的大盘股公司更适合风险寻求型投资者;相比之下,低账面价值比的小盘股公司适合风险承受能力较低的投资者。此外,我们的实证结果对私营企业、投资者和政策制定者具有重要意义。
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引用次数: 0
Federated statistical analysis: non-parametric testing and quantile estimation 联邦统计分析:非参数检验和分位数估计
Q3 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2023-11-13 DOI: 10.3389/fams.2023.1267034
Ori Becher, Mira Marcus-Kalish, David M. Steinberg
The age of big data has fueled expectations for accelerating learning. The availability of large data sets enables researchers to achieve more powerful statistical analyses and enhances the reliability of conclusions, which can be based on a broad collection of subjects. Often such data sets can be assembled only with access to diverse sources; for example, medical research that combines data from multiple centers in a federated analysis. However these hopes must be balanced against data privacy concerns, which hinder sharing raw data among centers. Consequently, federated analyses typically resort to sharing data summaries from each center. The limitation to summaries carries the risk that it will impair the efficiency of statistical analysis procedures. In this work, we take a close look at the effects of federated analysis on two very basic problems, non-parametric comparison of two groups and quantile estimation to describe the corresponding distributions. We also propose a specific privacy-preserving data release policy for federated analysis with the K -anonymity criterion, which has been adopted by the Medical Informatics Platform of the European Human Brain Project. Our results show that, for our tasks, there is only a modest loss of statistical efficiency.
大数据时代激发了人们对加速学习的期望。大数据集的可用性使研究人员能够实现更强大的统计分析,并提高结论的可靠性,这可以基于广泛的主题集合。这些数据集往往只能通过不同的来源来收集;例如,将来自多个中心的数据结合在一起进行联合分析的医学研究。然而,这些希望必须与数据隐私问题相平衡,这阻碍了中心之间共享原始数据。因此,联邦分析通常求助于共享来自每个中心的数据摘要。对摘要的限制有可能损害统计分析程序的效率。在这项工作中,我们仔细研究了联邦分析对两个非常基本的问题的影响,两组的非参数比较和描述相应分布的分位数估计。我们还提出了一种特定的隐私保护数据发布策略,该策略采用K -匿名标准进行联邦分析,该策略已被欧洲人脑项目的医学信息平台采用。我们的结果表明,对于我们的任务来说,统计效率只会有轻微的损失。
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引用次数: 0
Examining share repurchase executions: insights and synthesis from the existing literature 审查股票回购执行:从现有文献的见解和综合
Q3 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2023-11-08 DOI: 10.3389/fams.2023.1265254
Joerg Osterrieder, Michael Seigne
This literature review aims to address the critical knowledge gap in the field of share repurchase executions, a financial activity involving companies repurchasing trillions of dollars' worth of their own shares. The significance of understanding these mechanisms and their impact is underscored by their potential influence on the global economy. The paper employs a comprehensive analysis of existing literature, focusing on share repurchase mechanisms and motivations. It scrutinizes both open-market repurchases and Accelerated Share Repurchase contracts. Methodological approaches in current research, such as the use of partial differential equations and tree methods, are also evaluated. The review reveals that the execution phase of share repurchases remains largely unexplored. Unanswered questions persist about trading schedules, implications, costs, broker and corporate performance, and psychological effects of beating a buyback benchmark. Additionally, the review identifies significant limitations in current research methodologies. The paper advocates for the application and development of more advanced tools like machine learning and artificial intelligence to address these gaps. It also suggests potential areas for future research, including the role of technology in share repurchase execution, psychological factors influencing corporate buybacks, and the development of performance metrics for brokers and corporations. The review serves not only to highlight existing gaps in literature but also to suggest avenues for future research that could fundamentally enhance our understanding of share repurchase executions. JEL classification G1, G12, G14, G02, G4.
本文献综述旨在解决股票回购执行领域的关键知识缺口,股票回购执行是一项涉及公司回购价值数万亿美元的股票的金融活动。这些机制对全球经济的潜在影响凸显了理解这些机制及其影响的重要性。本文对现有文献进行了综合分析,重点研究了股票回购的机制和动机。它审查公开市场回购和加速股票回购合同。方法学方法在当前的研究,如使用偏微分方程和树的方法,也进行了评估。审查显示,股票回购的执行阶段在很大程度上仍未得到探索。有关交易时间表、影响、成本、经纪商和公司业绩,以及超过回购基准的心理影响等尚未解决的问题依然存在。此外,该综述还指出了当前研究方法的重大局限性。这篇论文提倡应用和开发更先进的工具,如机器学习和人工智能,以解决这些差距。本文还提出了未来研究的潜在领域,包括技术在股票回购执行中的作用,影响公司回购的心理因素,以及经纪人和公司绩效指标的发展。这篇综述不仅突出了文献中存在的差距,而且为未来的研究提供了途径,这些研究可以从根本上增强我们对股票回购执行的理解。JEL分类G1、G12、G14、G02、G4。
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引用次数: 0
Log-Kumaraswamy distribution: its features and applications Log-Kumaraswamy分布:特征与应用
Q3 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2023-10-31 DOI: 10.3389/fams.2023.1258961
Aliyu Ismail Ishaq, Ahmad Abubakar Suleiman, Hanita Daud, Narinderjit Singh Sawaran Singh, Mahmod Othman, Rajalingam Sokkalingam, Pitchaya Wiratchotisatian, Abdullahi Garba Usman, Sani Isah Abba
This article aimed to present a new continuous probability density function for a non-negative random variable that serves as an alternative to some bounded domain distributions. The new distribution, termed the log-Kumaraswamy distribution, could faithfully be employed to compete with bounded and unbounded random processes. Some essential features of this distribution were studied, and the parameters of its estimates were obtained based on the maximum product of spacing, least squares, and weighted least squares procedures. The new distribution was proven to be better than traditional models in terms of flexibility and applicability to real-life data sets.
本文旨在为非负随机变量提供一个新的连续概率密度函数,作为一些有界域分布的替代方案。新的分布,称为log-Kumaraswamy分布,可以忠实地用来与有界和无界随机过程竞争。研究了该分布的一些基本特征,并基于最大间距积、最小二乘法和加权最小二乘法得到了其估计参数。新的分布被证明在灵活性和对实际数据集的适用性方面优于传统模型。
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引用次数: 0
Modeling and bifurcation analysis of tuberculosis with the multidrug-resistant compartment incorporating chemoprophylaxis treatment 结合化学预防治疗的多药耐药区室肺结核的建模和分岔分析
Q3 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2023-10-31 DOI: 10.3389/fams.2023.1264201
Damtew Bewket Kitaro, Boka Kumsa Bole, Koya Purnachandra Rao
Tuberculosis is a major health problem that contributes significantly to infectious disease mortality worldwide. A new challenge for society that demands extensive work toward implementing the right control strategies for Tuberculosis (TB) is the emergence of drug-resistant TB. In this study, we developed a mathematical model to investigate the effect of chemoprophylaxis treatment on the transmission of tuberculosis with the drug-resistant compartment. An analysis of stabilities is performed along with an investigation into the possibility of endemic and disease-free equilibrium. The qualitative outcome of the model analysis shows that Disease Free Equilibrium (DFE) is locally asymptotically stable for R 0 < 1, but the endemic equilibrium becomes globally asymptotically stable for R 0 > 1. A bifurcation analysis was performed using the center manifold theorem, and it was found that the model shows evidence of forward bifurcation. Furthermore, the sensitivity analysis of the model was thoroughly carried out, and numerical simulation was also performed. This study showed that administering chemoprophylaxis treatment to individuals with latent infections significantly reduces the progression of exposed individuals to the infectious and drug-resistant classes, ultimately leading to a reduction in the transmission of the disease at large.
结核病是一个主要的健康问题,在很大程度上造成了全世界传染病的死亡。社会面临的一项新挑战是耐药结核病的出现,需要开展广泛工作以实施正确的结核病控制战略。在这项研究中,我们建立了一个数学模型来研究化学预防治疗对耐药室结核传播的影响。对稳定性进行分析,同时对地方性和无病平衡的可能性进行调查。模型分析的定性结果表明,无病平衡(DFE)在R = 0时是局部渐近稳定的。1,但地方性平衡在r0 >时变得全局渐近稳定;1. 利用中心流形定理进行了分岔分析,发现该模型具有正向分岔的证据。在此基础上,对模型进行了敏感性分析,并进行了数值模拟。这项研究表明,对潜伏感染的个体进行化学预防治疗可显著减少暴露于传染性和耐药类的个体的进展,最终导致总体上减少疾病的传播。
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引用次数: 0
Simulating time-to-event data under the Cox proportional hazards model: assessing the performance of the non-parametric Flexible Hazards Method 在Cox比例风险模型下模拟时间事件数据:评估非参数柔性风险方法的性能
Q3 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2023-10-30 DOI: 10.3389/fams.2023.1272334
Jennifer L. Delzeit, Devin C. Koestler
Numerous methods and approaches have been developed for generating time-to-event data from the Cox Proportional Hazards (CPH) model; however, they often require specification of a parametric distribution for the baseline hazard even though the CPH model itself makes no assumptions on the distribution of the baseline hazards. In line with the semi-parametric nature of the CPH model, a recently proposed method called the Flexible Hazards Method generates time-to-event data from a CPH model using a non-parametric baseline hazard function. While the initial results of this method are promising, it has not yet been comprehensively assessed with increasing covariates or against data generated under parametric baseline hazards. To fill this gap, we conducted a comprehensive study to benchmark the performance of the Flexible Hazards Method for generating data from a CPH model against parametric methods. Our results showed that with a single covariate and large enough assumed maximum time, the bias in the Flexible Hazards Method is 0.02 (with respect to the log hazard ratio) with a 95% confidence interval having coverage of 84.4%. This bias increases to 0.054 when there are 10 covariates under the same settings and the coverage of the 95% confidence interval decreases to 46.7%. In this paper, we explain the plausible reasons for this observed increase in bias and decrease in coverage as the number of covariates are increased, both empirically and theoretically, and provide readers and potential users of this method with some suggestions on how to best address these issues. In summary, the Flexible Hazards Method performs well when there are few covariates and the user wishes to simulate data from a non-parametric baseline hazard.
从Cox比例风险(CPH)模型中生成事件时间数据已经开发了许多方法和方法;然而,即使CPH模型本身没有对基线危害的分布做出假设,它们也经常需要对基线危害的参数分布进行说明。根据CPH模型的半参数性质,最近提出了一种称为柔性危害方法的方法,该方法使用非参数基线危害函数从CPH模型生成事件时间数据。虽然该方法的初步结果是有希望的,但尚未通过增加协变量或根据参数基线危险产生的数据对其进行全面评估。为了填补这一空白,我们进行了一项全面的研究,对柔性危害方法的性能进行基准测试,以从CPH模型中生成数据,并与参数方法进行比较。我们的结果表明,在单个协变量和足够大的假设最大时间下,灵活风险方法的偏差为0.02(相对于对数风险比),95%的置信区间覆盖率为84.4%。当相同设置下有10个协变量时,该偏差增加到0.054,95%置信区间的覆盖率下降到46.7%。在本文中,我们从经验和理论上解释了随着协变量数量的增加而观察到的偏倚增加和覆盖率下降的合理原因,并为读者和该方法的潜在用户提供了一些关于如何最好地解决这些问题的建议。总而言之,当协变量较少且用户希望从非参数基线风险中模拟数据时,柔性风险方法表现良好。
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引用次数: 0
A COVID-19 epidemic model with periodicity in transmission and environmental dynamics 具有传播周期和环境动力学的COVID-19流行病模型
Q3 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2023-10-24 DOI: 10.3389/fams.2023.1142625
Belthasara Assan, Farai Nyabadza
From the beginning of the outbreak of SARS-CoV-2 (COVID-19), South African data depicted seasonal transmission patterns, with infections rising in summer and winter every year. Seasonality, control measures, and the role of the environment are the most important factors in periodic epidemics. In this study, a deterministic model incorporating the influences of seasonality, vaccination, and the role of the environment is formulated to determine how these factors impact the epidemic. We analyzed the stability of the model, demonstrating that when R 0 < 1, the disease-free equilibrium is globally symptomatically stable, whereas R 0 > 1 indicates that the disease uniformly persists and at least one positive periodic solution exists. We demonstrate its application by using the data reported by the National Institute for Communicable Diseases. We fitted our mathematical model to the data from the third wave to the fifth wave and used a damping effect due to mandatory vaccination in the fifth wave. Our analytical and numerical results indicate that different efficacies for vaccination have a different influence on epidemic transmission at different seasonal periods. Our findings also indicate that as long as the coronavirus persists in the environment, the epidemic will continue to affect the human population and disease control should be geared toward the environment.
从SARS-CoV-2 (COVID-19)爆发开始,南非的数据描述了季节性传播模式,每年夏季和冬季感染人数都在上升。季节性、控制措施和环境的作用是造成周期性流行病的最重要因素。在这项研究中,制定了一个包含季节性、疫苗接种和环境作用影响的确定性模型,以确定这些因素如何影响流行病。我们分析了模型的稳定性,证明当R 0 <1、无病平衡是全局症状稳定的,而R 0 >1表示疾病均匀持续存在,且至少存在一个正周期解。我们通过使用国家传染病研究所报告的数据来演示其应用。我们将我们的数学模型拟合到从第三波到第五波的数据中,并使用了由于第五波强制接种疫苗而产生的阻尼效应。我们的分析和数值结果表明,不同的疫苗接种效果对不同季节的疫情传播有不同的影响。我们的研究结果还表明,只要冠状病毒在环境中持续存在,疫情就会继续影响人口,疾病控制应以环境为导向。
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引用次数: 1
Chi-square test for imprecise data in consistency table 一致性表中不精确数据的卡方检验
Q3 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2023-10-19 DOI: 10.3389/fams.2023.1279638
Muhammad Aslam, Florentin Smarandache
In this paper, we propose the introduction of a neutrosophic chi-square-test for consistency, incorporating neutrosophic statistics. Our aim is to modify the existing chi-square -test for consistency in order to analyze imprecise data. We present a novel test statistic for the neutrosophic chi-square -test for consistency, which accounts for the uncertainties inherent in the data. To evaluate the performance of the proposed test, we compare it with the traditional chi-square -test for consistency based on classical statistics. By conducting a comparative analysis, we assess the efficiency and effectiveness of our proposed neutrosophic chi-square -test for consistency. Furthermore, we illustrate the application of the proposed test through a numerical example, demonstrating how it can be utilized in practical scenarios. Through this implementation, we aim to provide empirical evidence of the improved performance of our proposed test when compared to the traditional chi-square-test for consistency based on classical statistics. We anticipate that the proposed neutrosophic chi-square -test for consistency will outperform its classical counterpart, offering enhanced accuracy and reliability when dealing with imprecise data. This advancement has the potential to contribute significantly to the field of statistical analysis, particularly in situations where data uncertainty and imprecision are prevalent.
在本文中,我们建议引入中性卡方检验来检验一致性,并结合中性统计学。我们的目的是修改现有的卡方检验的一致性,以便分析不精确的数据。我们提出了一种新的中性卡方一致性检验统计量,它解释了数据中固有的不确定性。为了评估所提出的检验的性能,我们将其与基于经典统计的传统卡方一致性检验进行了比较。通过进行比较分析,我们评估了我们提出的中性卡方一致性检验的效率和有效性。此外,我们通过一个数值例子说明了所提出的测试的应用,展示了如何在实际场景中使用它。通过这种实现,我们的目标是提供经验证据,证明与基于经典统计的传统卡方一致性检验相比,我们提出的检验的性能有所提高。我们预计,提出的中性卡方一致性检验将优于其经典对口检验,在处理不精确数据时提供更高的准确性和可靠性。这一进展有可能对统计分析领域作出重大贡献,特别是在数据普遍不确定和不精确的情况下。
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引用次数: 0
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