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An agent-based multi-level model to study the spread of gonorrhea in different and interacting risk groups 一个基于agent的多层模型,用于研究淋病在不同和相互作用的风险群体中的传播
Q3 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2023-10-13 DOI: 10.3389/fams.2023.1241538
Paola Stolfi, Davide Vergni, Filippo Castiglione
Introduction Mathematical modeling has emerged as a crucial component in understanding the epidemiology of infectious diseases. In fact, contemporary surveillance efforts for epidemic or endemic infections heavily rely on mathematical and computational methods. This study presents a novel agent-based multi-level model that depicts the transmission dynamics of gonorrhea, a sexually transmitted infection (STI) caused by the bacterium Neisseria gonorrhoeae . This infection poses a significant public health challenge as it is endemic in numerous countries, and each year sees millions of new cases, including a concerning number of drug-resistant cases commonly referred to as gonorrhea superbugs or super gonorrhea. These drug-resistant strains exhibit a high level of resistance to recommended antibiotic treatments. Methods The proposed model incorporates a multi-layer network of agents' interaction representing the dynamics of sexual partnerships. It also encompasses a transmission model, which quantifies the probability of infection during sexual intercourse, and a within-host model, which captures the immune activation following gonorrhea infection in an individual. It is a combination of agent-based modeling, which effectively captures interactions among various risk groups, and probabilistic modeling, which enables a theoretical exploration of sexual network characteristics and contagion dynamics. Results Numerical simulations of the dynamics of gonorrhea infection using the complete agent-based model are carried out. In particular, some examples of possible epidemic evolution are presented together with an application to a real case study. The goal was to construct a virtual population that closely resembles the target population of interest. Discussion The uniqueness of this research lies in its objective to accurately depict the influence of distinct sexual risk groups and their interaction on the prevalence of gonorrhea. The proposed model, having interpretable and measurable parameters from epidemiological data, facilitates a more comprehensive understanding of the disease evolution.
数学建模已经成为理解传染病流行病学的一个重要组成部分。事实上,当代对流行病或地方性感染的监测工作严重依赖于数学和计算方法。本研究提出了一种新的基于agent的多层模型,描述了淋病的传播动力学,淋病是一种由淋病奈瑟菌引起的性传播感染(STI)。这种感染对公共卫生构成重大挑战,因为它在许多国家流行,每年出现数百万新病例,包括通常被称为淋病超级细菌或超级淋病的相当数量的耐药病例。这些耐药菌株对推荐的抗生素治疗表现出高度的耐药性。方法提出的模型结合了一个多层代理互动网络,代表了性伙伴关系的动态。它还包括一个传播模型,量化性交期间感染的可能性,以及一个宿主内模型,捕捉个体感染淋病后的免疫激活。它结合了基于agent的建模和概率建模,前者可以有效地捕捉各种风险群体之间的相互作用,后者可以从理论上探索性网络特征和传染动力学。结果采用基于完全主体的模型对淋病感染动力学进行了数值模拟。特别是,提出了一些可能的流行病演变的例子,并将其应用于实际案例研究。目标是构建一个与感兴趣的目标种群非常相似的虚拟种群。本研究的独特之处在于其目的是准确描述不同的性风险群体及其相互作用对淋病流行的影响。该模型具有可解释和可测量的流行病学数据参数,有助于更全面地了解疾病演变。
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引用次数: 0
Multilevel IRT models to explore heterogeneity in subjective financial knowledge at individual and regional levels: the Italian case 在个人和地区层面探索主观金融知识异质性的多层次IRT模型:意大利案例
Q3 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2023-10-04 DOI: 10.3389/fams.2023.1278146
Rosa Fabbricatore, Lucio Palazzo
Introduction Modern FinTech tools (e.g., instant payments, blockchain, roboadvisor) represent the new frontier of digital finance. Consequently, the evaluation of the knowledge level of the population about these topics is a crucial concern. In this context, several exogenous factors may influence individual differences in financial literacy. In particular, the territorial characteristics can have an impact on FinTech. In this work, we investigate individual heterogeneity in subjective financial knowledge in Italy, specifically focusing on modern FinTech tools, and exploring the differences at the individual and regional levels. Methods A sample of 598 Italian individuals from 10 different Italian regions was involved. A multilevel IRT model is performed to evaluate the level of FinTech individual knowledge and the differences according to Italian regions to account for the hierarchical structure of the data. Results Results reported a weak regional effect, revealing that heterogeneity in financial knowledge can be mainly attributed to individual characteristics. At the individual level, age, economic condition, knowledge of traditional financial objects and numeracy showed a significant effect. In addition, a scientific field of study and work have an impact on respondents' knowledge level. Discussion What is shown and discussed in this contribution can inspire policymakers' actions to increase financial literacy in the population. In particular, the obtained results imply that policymakers should improve the population's awareness of less popular FinTech tools and foster individuals' literacy about numbers and traditional financial tools, which proved to have a great influence in explaining FinTech knowledge differences.
现代金融科技工具(如即时支付、区块链、roboadvisor)代表了数字金融的新前沿。因此,评价人口对这些问题的知识水平是一个至关重要的问题。在这种背景下,几个外生因素可能会影响个人在金融素养方面的差异。特别是,地域特征会对金融科技产生影响。在这项工作中,我们调查了意大利主观金融知识的个体异质性,特别关注现代金融科技工具,并探讨了个人和地区层面的差异。方法对来自意大利10个不同地区的598名意大利人进行调查。采用多层IRT模型来评估金融科技个人知识水平和意大利各地区的差异,以解释数据的层次结构。结果金融知识的区域效应较弱,表明金融知识的异质性主要是由个体特征决定的。在个人层面上,年龄、经济状况、对传统金融对象的了解和计算能力表现出显著的影响。此外,科学的学习和工作领域对被调查者的知识水平也有影响。本书所展示和讨论的内容可以激励政策制定者采取行动,提高民众的金融知识素养。特别是,所获得的结果表明,政策制定者应该提高民众对不太受欢迎的金融科技工具的认识,培养个人对数字和传统金融工具的素养,这被证明对解释金融科技知识差异有很大的影响。
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引用次数: 0
Image segmentation using active contours with image structure adaptive gradient vector flow external force 图像分割利用活动轮廓与图像结构自适应梯度矢量流外力
Q3 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2023-10-04 DOI: 10.3389/fams.2023.1271296
Dong Wang, Xing Dang, Weijing Liu, Yuanquan Wang
Introduction Gradient vector flow (GVF) has been proven as an effective external force for active contours. However, its smoothness constraint does not take the image structure into account, such that the GVF diffusion is isotropic and cannot preserve weak edges well. Methods In this article, an image structure adaptive gradient vector flow (ISAGVF) external force is proposed for active contours. In the proposed ISAGVF model, the smoothness constraint is first reformulated in matrix form, and then the image structure tensor is incorporated. As the structure tensor characterizes the image structure well, the proposed ISAGVF model can be adaptive to image structure, and the ISAGVF snake performs well on weak edge preservation and deep concavity convergence while possessing some other desirable properties of the GVF snake, such as enlarged capture range and insensitivity to initialization. Results Experiments on synthetic and real images manifest these properties of the ISAGVF snake.
梯度矢量流(GVF)已被证明是一种有效的运动轮廓的外力。但其平滑性约束没有考虑图像结构,使得梯度矢量流场扩散是各向同性的,不能很好地保留弱边缘。方法针对活动轮廓,提出了一种图像结构自适应梯度矢量流(ISAGVF)外力。在该ISAGVF模型中,首先将平滑性约束重新表述为矩阵形式,然后引入图像结构张量。由于结构张量较好地表征了图像结构,因此所提出的ISAGVF模型能够自适应图像结构,ISAGVF蛇形具有较好的弱边缘保存和深凹性收敛性,同时具有GVF蛇形的一些优良特性,如较大的捕获范围和对初始化的不敏感。结果ISAGVF蛇在合成图像和真实图像上的实验证明了这些特性。
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引用次数: 0
Fractional-order projection of a chaotic system with hidden attractors and its passivity-based synchronization 含隐吸引子混沌系统的分数阶投影及其无源同步
Q3 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2023-09-26 DOI: 10.3389/fams.2023.1267664
Fernando E. Serrano, Jesus M. Munoz-Pacheco, Marco A. Flores
This paper presents the fractional-order projection of a chaotic system, which delivers a collection of self-excited and hidden chaotic attractors as a function of a single system parameter. Based on an integer-order chaotic system and the proposed transformation, the fractional-order chaotic system obtains when the divergence of integer and fractional vector fields flows in the same direction. Phase portraits, bifurcation diagrams, and Lyapunov exponents validate the chaos generation. Apart from these results, two passivity-based fractional control laws are designed effectively for the integer and fractional-order chaotic systems. In both cases, the synchronization schemes depend on suitable storage functions given by the fractional Lyapunov theory. Several numerical experiments confirm the proposed approach and agree well with the mathematical deductions.
本文给出了一个混沌系统的分数阶投影,它给出了一组自激和隐藏混沌吸引子作为单个系统参数的函数。基于整数阶混沌系统和所提出的变换,得到了整数和分数阶矢量场散度方向相同时的分数阶混沌系统。相肖像,分岔图,和李亚普诺夫指数验证混沌的产生。在此基础上,针对整数阶和分数阶混沌系统,设计了两种基于被动的分数阶控制律。在这两种情况下,同步方案依赖于分数李雅普诺夫理论给出的合适的存储函数。几个数值实验验证了所提出的方法,并与数学推导结果很好地吻合。
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引用次数: 0
Text classification in fair competition law violations using deep learning 基于深度学习的公平竞争法违规文本分类
Q3 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2023-09-22 DOI: 10.3389/fams.2023.1177081
Yinying Kong, Niangqiu Huang, Haodong Deng, Junwen Feng, Xingyi Liang, Weisi Lv, Jingyi Liu
Introduction Ensuring fair competition through manual review is a complex undertaking. This paper introduces the utilization of Long Short-Term Memory (LSTM) neural networks and TextCNN to establish a text classifier for classifying and reviewing normative documents. Methods The experimental dataset used consists of policy measure samples provided by the antitrust division of the Guangdong Market Supervision Administration. We conduct a comparative analysis of the performance of LSTM and TextCNN classification models. Results In three classification experiments conducted without an enhanced experimental dataset, the LSTM classifier achieved an accuracy of 95.74%, while the TextCNN classifier achieved an accuracy of 92.7% on the test set. Conversely, in three classification experiments utilizing an enhanced experimental dataset, the LSTM classifier demonstrated an accuracy of 96.36%, and the TextCNN classifier achieved an accuracy of 96.19% on the test set. Discussion The experimental results highlight the effectiveness of LSTM and TextCNN in classifying and reviewing normative documents. The superior accuracy achieved with the enhanced experimental dataset underscores the potential of these models in real-world applications, particularly in tasks involving fair competition review.
通过人工审查确保公平竞争是一项复杂的工作。本文介绍了利用长短期记忆(LSTM)神经网络和TextCNN建立一个文本分类器,用于对规范性文件进行分类和审阅。方法实验数据集采用广东省市场监督管理局反垄断司提供的政策措施样本。我们对LSTM和TextCNN分类模型的性能进行了比较分析。结果在没有增强实验数据集的情况下进行的3次分类实验中,LSTM分类器的准确率为95.74%,TextCNN分类器在测试集上的准确率为92.7%。相反,在使用增强实验数据集的三个分类实验中,LSTM分类器在测试集上的准确率为96.36%,TextCNN分类器在测试集上的准确率为96.19%。实验结果突出了LSTM和TextCNN在规范文件分类和审查方面的有效性。通过增强的实验数据集获得的卓越准确性强调了这些模型在现实应用中的潜力,特别是在涉及公平竞争审查的任务中。
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引用次数: 0
Efficiency enhancement of the modified EWMA control method with conditional expected delay for change detection in processes 基于条件期望延迟的改进EWMA控制方法在过程变化检测中的效率提高
Q3 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2023-09-15 DOI: 10.3389/fams.2023.1268340
Nasrullah Khan, Muhammad Aslam, Mohammed Albassam
This study investigates the efficiency of a modified exponentially weighted moving average (EWMA) control method using conditional expected delay to improve its efficiency in detecting changes in a process over time. While the modified EWMA control method is commonly used for this purpose, it can sometimes experience delays in detecting changes. The proposed method aims to address this limitation by incorporating conditional expected delay. The study utilizes simulations to conduct a performance comparison between the modified EWMA control method and the conventional EWMA control, employing the metric of conditional expected delay. Simulation results demonstrate the modified EWMA control method with conditional expected delay in terms of accurately and rapidly detecting changes. Overall, this study concludes that the integration of conditional expected delay into the modified EWMA control method can increase its effectiveness in detecting changes in a process. This has significant practical implications for a variety of industries that require timely and accurate detection of changes to maintain product quality and optimize processes.
本文研究了一种改进的指数加权移动平均(EWMA)控制方法的效率,该方法使用条件期望延迟来提高其检测过程随时间变化的效率。虽然改进的EWMA控制方法通常用于此目的,但它有时会在检测变化时遇到延迟。提出的方法旨在通过合并条件预期延迟来解决这一限制。采用条件期望延迟度量,通过仿真对改进的EWMA控制方法与传统EWMA控制方法进行性能比较。仿真结果表明,基于条件期望延迟的改进EWMA控制方法能够准确、快速地检测变化。综上所述,本研究认为将条件期望延迟整合到改进的EWMA控制方法中可以提高其检测过程变化的有效性。这对于需要及时和准确地检测变化以保持产品质量和优化过程的各种行业具有重要的实际意义。
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引用次数: 0
Lagrangian motion magnification with double sparse optical flow decomposition 双稀疏光流分解的拉格朗日运动放大
Q3 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2023-09-14 DOI: 10.3389/fams.2023.1164491
Philipp Flotho, Cosmas Heiss, Gabriele Steidl, Daniel J. Strauss
Microexpressions are fast and spatially small facial expressions that are difficult to detect. Therefore, motion magnification techniques, which aim at amplifying and hence revealing subtle motion in videos, appear useful for handling such expressions. There are basically two main approaches, namely, via Eulerian or Lagrangian techniques. While the first one magnifies motion implicitly by operating directly on image pixels, the Lagrangian approach uses optical flow (OF) techniques to extract and magnify pixel trajectories. In this study, we propose a novel approach for local Lagrangian motion magnification of facial micro-motions. Our contribution is 3-fold: first, we fine tune the recurrent all-pairs field transforms (RAFT) for OFs deep learning approach for faces by adding ground truth obtained from the variational dense inverse search (DIS) for the OF algorithm applied to the CASME II video set of facial micro expressions. This enables us to produce OFs of facial videos in an efficient and sufficiently accurate way. Second, since facial micro-motions are both local in space and time, we propose to approximate the OF field by sparse components both in space and time leading to a double sparse decomposition. Third, we use this decomposition to magnify micro-motions in specific areas of the face, where we introduce a new forward warping strategy using a triangular splitting of the image grid and barycentric interpolation of the RGB vectors at the corners of the transformed triangles. We demonstrate the feasibility of our approach by various examples.
微表情是一种快速且空间小的面部表情,很难被发现。因此,旨在放大并显示视频中细微动作的运动放大技术似乎对处理这种表情很有用。基本上有两种主要的方法,即通过欧拉或拉格朗日技术。第一种方法通过直接操作图像像素来隐式放大运动,而拉格朗日方法使用光流(OF)技术来提取和放大像素轨迹。在这项研究中,我们提出了一种新的面部微运动局部拉格朗日运动放大方法。我们的贡献有三个方面:首先,我们通过为应用于CASME II面部微表情视频集的OF算法添加从变分密集逆搜索(DIS)中获得的地面真值,对用于人脸的OFs深度学习方法的循环全对场变换(RAFT)进行微调。这使得我们能够高效且足够准确地制作面部视频的OFs。其次,由于面部微运动在空间和时间上都是局部的,我们提出通过空间和时间上的稀疏分量来近似OF场,从而实现双稀疏分解。第三,我们使用这种分解来放大面部特定区域的微运动,其中我们引入了一种新的前向扭曲策略,使用图像网格的三角形分裂和变换三角形角的RGB矢量的质心插值。我们用不同的例子来证明我们方法的可行性。
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引用次数: 0
Numerical treatment for mathematical model of farming awareness in crop pest management 农作物病虫害管理中农业意识数学模型的数值处理
IF 1.4 Q3 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2023-09-07 DOI: 10.3389/fams.2023.1208774
Nabeela Anwar, Iftikhar Ahmad, A. Kiani, M. Shoaib, M. Raja
The most important factor for increasing crop production is pest and pathogen resistance, which has a major impact on global food security. Pest management also emphasizes the need for farming awareness. A high crop yield is ultimately achieved by protecting crops from pests and raising public awareness of the devastation caused by pests. In this research, we aim to investigate the intricate impacts of nonlinear delayed systems for managing crop pest management (CPM) supervised by Ordinary Differential Equations (ODEs). Our focus will be on highlighting the intricate and often unpredictable relationships that occur over time among crops, pests, strategies for rehabilitation, and environmental factors. The nonlinear delayed CPM model incorporated the four compartments: crop biomass density [B(t)], susceptible pest density [S(t)], infected pest density [I(t)], and population awareness level [A(t)]. The approximate solutions for the four compartments B(t), S(t), I(t), and A(t) are determined by the implementation of sundry scenarios generated with the variation in crop biomass growth rate, rate of pest attacks, pest natural death rate, disease associated death rate and memory loss of aware people, by means of exploiting the strength of the Adams (ADS) and explicit Runge-Kutta (ERK) numerical solvers. Comparative analysis of the designed approach is carried out for the dynamic impacts of the nonlinear delayed CPM model in terms of numerical outcomes and simulations based on sundry scenarios.
提高作物产量的最重要因素是对害虫和病原体的抵抗力,这对全球粮食安全有重大影响。病虫害管理也强调了提高农业意识的必要性。通过保护作物免受害虫侵害和提高公众对害虫造成的破坏的认识,最终可以实现高产量。在本研究中,我们旨在研究非线性延迟系统对常微分方程(ODEs)监督下的作物病虫害管理(CPM)的复杂影响。我们的重点将是强调随着时间的推移,作物、害虫、恢复策略和环境因素之间发生的复杂且往往不可预测的关系。非线性延迟CPM模型包含四个部分:作物生物量密度[B(t)]、易感害虫密度[S(t。四个区室B(t)、S(t),I(t)和A(t)的近似解是通过实施随着作物生物量增长率、害虫攻击率、害虫自然死亡率、疾病相关死亡率和有意识的人的记忆力丧失的变化而产生的各种情景来确定的,利用Adams(ADS)和显式Runge-Kutta(ERK)数值求解器的优点。针对非线性延迟CPM模型的动态影响,从数值结果和基于各种场景的模拟两个方面对所设计的方法进行了比较分析。
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引用次数: 0
The regime-conversion method: a hybrid technique for simulating well-mixed chemical reaction networks 状态转换法:一种模拟混合良好的化学反应网络的混合技术
IF 1.4 Q3 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2023-09-07 DOI: 10.3389/fams.2023.1107441
Joshua C. Kynaston, Christian A. Yates, Anna V. F. Hekkink, Chris Guiver
There exist several methods for simulating biological and physical systems as represented by chemical reaction networks. Systems with low numbers of particles are frequently modeled as discrete-state Markov jump processes and are typically simulated via a stochastic simulation algorithm (SSA). An SSA, while accurate, is often unsuitable for systems with large numbers of individuals, and can become prohibitively expensive with increasing reaction frequency. Large systems are often modeled deterministically using ordinary differential equations, sacrificing accuracy and stochasticity for computational efficiency and analytical tractability. In this paper, we present a novel hybrid technique for the accurate and efficient simulation of large chemical reaction networks. This technique, which we name the regime-conversion method, couples a discrete-state Markov jump process to a system of ordinary differential equations by simulating a reaction network using both techniques simultaneously. Individual molecules in the network are represented by exactly one regime at any given time, and may switch their governing regime depending on particle density. In this manner, we model high copy-number species using the cheaper continuum method and low copy-number species using the more expensive, discrete-state stochastic method to preserve the impact of stochastic fluctuations at low copy number. The motivation, as with similar methods, is to retain the advantages while mitigating the shortfalls of each method. We demonstrate the performance and accuracy of our method for several test problems that exhibit varying degrees of inter-connectivity and complexity by comparing averaged trajectories obtained from both our method and from exact stochastic simulation.
存在几种用于模拟以化学反应网络为代表的生物和物理系统的方法。具有低粒子数的系统通常被建模为离散状态马尔可夫跳跃过程,并且通常通过随机模拟算法(SSA)来模拟。SSA虽然准确,但通常不适用于具有大量个体的系统,并且随着反应频率的增加,其成本可能会高得令人望而却步。大型系统通常使用常微分方程进行确定性建模,为了计算效率和分析的可处理性,牺牲了精度和随机性。在本文中,我们提出了一种新的混合技术,用于精确有效地模拟大型化学反应网络。这种技术,我们称之为状态转换方法,通过同时使用这两种技术模拟反应网络,将离散状态马尔可夫跳跃过程耦合到常微分方程组。网络中的单个分子在任何给定时间都由一个区域表示,并且可以根据粒子密度切换其控制区域。通过这种方式,我们使用更便宜的连续体方法对高拷贝数物种进行建模,使用更昂贵的离散状态随机方法对低拷贝数物种建模,以保持低拷贝数下随机波动的影响。与类似方法一样,动机是保留每种方法的优势,同时减少不足。我们通过比较从我们的方法和精确随机模拟中获得的平均轨迹,证明了我们的方法对几个测试问题的性能和准确性,这些测试问题表现出不同程度的相互连通性和复杂性。
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引用次数: 0
Parameter-uniformly convergent numerical scheme for singularly perturbed delay parabolic differential equation via extended B-spline collocation 基于扩展b样条配置的奇摄动时滞抛物型微分方程参数一致收敛的数值格式
IF 1.4 Q3 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2023-09-07 DOI: 10.3389/fams.2023.1255672
Zerihun Ibrahim Hassen, G. Duressa
This paper presents a parameter-uniform numerical method to solve the time dependent singularly perturbed delay parabolic convection-diffusion problems. The solution to these problems displays a parabolic boundary layer if the perturbation parameter approaches zero. The retarded argument of the delay term made to coincide with a mesh point and the resulting singularly perturbed delay parabolic convection-diffusion problem is approximated using the implicit Euler method in temporal direction and extended cubic B-spline collocation in spatial orientation by introducing artificial viscosity both on uniform mesh. The proposed method is shown to be parameter uniform convergent, unconditionally stable, and linear order of accuracy. Furthermore, the obtained numerical results agreed with the theoretical results.
本文提出了一种求解时变奇摄动时滞抛物型对流扩散问题的参数一致数值方法。如果扰动参数接近零,则这些问题的解显示出抛物线边界层。在时间方向上使用隐式Euler方法,在空间方向上使用扩展的三次B样条配置,通过在均匀网格上引入人工粘性,来近似使延迟项与网格点重合的延迟自变量和由此产生的奇摄动延迟抛物型对流扩散问题。结果表明,该方法参数一致收敛,无条件稳定,精度为线性阶。数值计算结果与理论计算结果基本一致。
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引用次数: 0
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Frontiers in Applied Mathematics and Statistics
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