Background: Thorax traumas form 20-25% of deaths resulting from trauma. In the young population, the most common reason for death resulting from trauma is thorax trauma. The investigation of blunt thorax trauma reveals that the most common reason in the young population is 'in-vehicle motor traffic accidents (IVMTA), while falls take the 1st place in the geriatric population. The relationship between the localization of rib fractures developing due to blunt thorax trauma and the resultant hemothorax, pneumothorax, or hemopneumothorax investigated, and results compared. Material and Method: Between the dates November 2018 and November 2019, thoracic computerized tomography views of a total of 81 patients who applied with blunt thorax trauma and rib fractures evaluated retrospectively. Rib fractures were divided into three as upper, middle and lower thoracic segments according to their localization. Results: The most common localization for rib fracture was the middle thoracic segment with 57 (70.3%) patients. The mean hospitalization period was 5.4 (range: 1-24) days. Additional pathological findings were hemothorax, pneumothorax, and hemopneumothorax in 20 (24.7%), 16 (19.8%), and 5 (6.2%) patients, respectively. Among thoracic segments where rib fractures encountered, the upper thoracic segment most commonly led to hemothorax and pneumothorax with 11 (32.3%) and 8 (23.5%) patients, respectively. Conclusion: The most common localization of rib fractures following blunt thorax trauma is the upper and middle thoracic segment. In the upper thoracic segment, emergency thorax surgery complications like hemothorax/pneumothorax follow posttraumatic rib fractures in the earlier term and are more common when compared to other segments. The segmental localization of rib fractures developing due to blunt thorax trauma is essential in terms of morbidities, and the decision of invasive or conservative treatment depends on this information.
{"title":"Localization of rib fractures following blunt thorax trauma and investigating the relationship between these and traumatic hemopneumothorax","authors":"S. Akboğa, Y. Akkas","doi":"10.51271/kmj-0069","DOIUrl":"https://doi.org/10.51271/kmj-0069","url":null,"abstract":" \u0000Background: Thorax traumas form 20-25% of deaths resulting from trauma. In the young population, the most common reason for death resulting from trauma is thorax trauma. The investigation of blunt thorax trauma reveals that the most common reason in the young population is 'in-vehicle motor traffic accidents (IVMTA), while falls take the 1st place in the geriatric population. The relationship between the localization of rib fractures developing due to blunt thorax trauma and the resultant hemothorax, pneumothorax, or hemopneumothorax investigated, and results compared.\u0000Material and Method: Between the dates November 2018 and November 2019, thoracic computerized tomography views of a total of 81 patients who applied with blunt thorax trauma and rib fractures evaluated retrospectively. Rib fractures were divided into three as upper, middle and lower thoracic segments according to their localization.\u0000Results: The most common localization for rib fracture was the middle thoracic segment with 57 (70.3%) patients. The mean hospitalization period was 5.4 (range: 1-24) days. Additional pathological findings were hemothorax, pneumothorax, and hemopneumothorax in 20 (24.7%), 16 (19.8%), and 5 (6.2%) patients, respectively. Among thoracic segments where rib fractures encountered, the upper thoracic segment most commonly led to hemothorax and pneumothorax with 11 (32.3%) and 8 (23.5%) patients, respectively.\u0000Conclusion: The most common localization of rib fractures following blunt thorax trauma is the upper and middle thoracic segment. In the upper thoracic segment, emergency thorax surgery complications like hemothorax/pneumothorax follow posttraumatic rib fractures in the earlier term and are more common when compared to other segments. The segmental localization of rib fractures developing due to blunt thorax trauma is essential in terms of morbidities, and the decision of invasive or conservative treatment depends on this information.","PeriodicalId":369732,"journal":{"name":"Kastamonu Medical Journal","volume":"18 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"113963934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Berkay Küçük, Gul Meral Kocabeyoglu, Sevil BALTACI ÖZEN, B. D. Kosovali, N. M. Mutlu, Esra YAKIŞIK ÇAKIR, Işıl Özkoçak Turan, Y. Bag, Abdullah Bulğurcu
Aim: The Delta Neutrophil Index (DNI) shows the ratio of immature granulocytes in the circulation and increases in conditions of infection and inflammation. The aim of this study was to investigate the suitability of using DNI as a prognostic marker of mortality in COVID-19 patients in the Intensive Care Unit (ICU). Material and Method: This retrospective study included 316 patients followed up in the ICU with a diagnosis of COVID-19. A record was made for each patient of demographic data, laboratory values, clinical results and mortality status. All the data of the patients were evaluated and compared between the two groups of surviving and non-surviving patients. Results: Mortality developed in 181 (57.27%) patients. The Glasgow Coma Scale score was lower and the APACHE II and SOFA scores were higher in the mortality group than in the surviving group (p<0.001 for all). The creatinine, procalcitonin, white blood cell, neutrophil count, neutrophil-lymphocyte ratio, lactate, interleukin -6 and C-reactive protein values were statistically significantly higher in the mortality group. In the comparison of DNI between the groups, a statistically significant difference was only determined on day 3 (p=0.026). For the DNI examined on day 3, the AUC value was 0.574 and the cutoff value was 1.35% for the prediction of mortality. Conclusion: DNI, which is low cost and simple to use, can be considered safe for use in the prediction of mortality of ICU patients diagnosed with COVID-19. The monitoring of increasing or decreasing trends by keeping regular records can be considered important for the clinical course.
{"title":"Prognostic marker for mortality of COVID-19 patients in the intensive care unit: the delta neutrophil index","authors":"Berkay Küçük, Gul Meral Kocabeyoglu, Sevil BALTACI ÖZEN, B. D. Kosovali, N. M. Mutlu, Esra YAKIŞIK ÇAKIR, Işıl Özkoçak Turan, Y. Bag, Abdullah Bulğurcu","doi":"10.51271/kmj-0057","DOIUrl":"https://doi.org/10.51271/kmj-0057","url":null,"abstract":" \u0000Aim: The Delta Neutrophil Index (DNI) shows the ratio of immature granulocytes in the circulation and increases in conditions of infection and inflammation. The aim of this study was to investigate the suitability of using DNI as a prognostic marker of mortality in COVID-19 patients in the Intensive Care Unit (ICU).\u0000Material and Method: This retrospective study included 316 patients followed up in the ICU with a diagnosis of COVID-19. A record was made for each patient of demographic data, laboratory values, clinical results and mortality status. All the data of the patients were evaluated and compared between the two groups of surviving and non-surviving patients.\u0000Results: Mortality developed in 181 (57.27%) patients. The Glasgow Coma Scale score was lower and the APACHE II and SOFA scores were higher in the mortality group than in the surviving group (p<0.001 for all). The creatinine, procalcitonin, white blood cell, neutrophil count, neutrophil-lymphocyte ratio, lactate, interleukin -6 and C-reactive protein values were statistically significantly higher in the mortality group. In the comparison of DNI between the groups, a statistically significant difference was only determined on day 3 (p=0.026). For the DNI examined on day 3, the AUC value was 0.574 and the cutoff value was 1.35% for the prediction of mortality.\u0000Conclusion: DNI, which is low cost and simple to use, can be considered safe for use in the prediction of mortality of ICU patients diagnosed with COVID-19. The monitoring of increasing or decreasing trends by keeping regular records can be considered important for the clinical course.","PeriodicalId":369732,"journal":{"name":"Kastamonu Medical Journal","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132226765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Şahin Tekin, A. Kalkan, Hande Ece Kalkan, G. Yorulmaz
Aim: The diagnosis of thyrotoxicosis in the first trimester of pregnancy is peculiar due to the physiological changes that occur due to pregnancy. There are maternal and fetal adverse effects of hyperthyroidism on pregnancy. In this study, we aimed to evaluate the effect of thyrotoxicosis on newborn weight in pregnant women with gestational transient thyrotoxicosis or Graves' disease who were referred for thyrotoxicosis in the first trimester. Material and Method: Ninety-four pregnant women in the first trimester with subclinical or overt hyperthyroidism caused by gestational transient thyrotoxicosis or Graves’ disease and 30 healthy pregnant women in the same trimester were included in the study. The birth weights of their babies were compared. Results: Ninety of the patients reached delivery, and four with gestational transient thyrotoxicosis had abortus due to obstetric reasons. No statistical difference was found in terms of the birth weights of the babies in the comparison between the gestational transient thyrotoxicosis, Graves’ disease, and the control groups (p>0.05). Conclusion: In our study, neither gestational transient thyrotoxicosis nor Graves' disease was found to be associated with low birth weight. But since it is known that overt hyperthyroidism may be associated with low birth weight, pregnant women with hyperthyroidism should be followed carefully.
{"title":"The effect of hyperthyroidism in the first trimester of pregnancy on low birth weight","authors":"M. Şahin Tekin, A. Kalkan, Hande Ece Kalkan, G. Yorulmaz","doi":"10.51271/kmj-0071","DOIUrl":"https://doi.org/10.51271/kmj-0071","url":null,"abstract":" \u0000Aim: The diagnosis of thyrotoxicosis in the first trimester of pregnancy is peculiar due to the physiological changes that occur due to pregnancy. There are maternal and fetal adverse effects of hyperthyroidism on pregnancy. In this study, we aimed to evaluate the effect of thyrotoxicosis on newborn weight in pregnant women with gestational transient thyrotoxicosis or Graves' disease who were referred for thyrotoxicosis in the first trimester.\u0000Material and Method: Ninety-four pregnant women in the first trimester with subclinical or overt hyperthyroidism caused by gestational transient thyrotoxicosis or Graves’ disease and 30 healthy pregnant women in the same trimester were included in the study. The birth weights of their babies were compared.\u0000Results: Ninety of the patients reached delivery, and four with gestational transient thyrotoxicosis had abortus due to obstetric reasons. No statistical difference was found in terms of the birth weights of the babies in the comparison between the gestational transient thyrotoxicosis, Graves’ disease, and the control groups (p>0.05).\u0000Conclusion: In our study, neither gestational transient thyrotoxicosis nor Graves' disease was found to be associated with low birth weight. But since it is known that overt hyperthyroidism may be associated with low birth weight, pregnant women with hyperthyroidism should be followed carefully.","PeriodicalId":369732,"journal":{"name":"Kastamonu Medical Journal","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131789474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aneurysm is defined as 50% enlargement of the normal diameter of the artery. The most common cause of true aneurysms is atherosclerosis. Pseudoaneurysms, on the other hand, occur as a result of the blood leaking from the tear in the arterial wall forming a thrombus formation and surrounding it with a fibrous capsule. In pseudoaneurysms, blood pools in a closed area. However, they may enlarge and rupture in the late period. Treatment options are thrombin injection, endovascular graft implantation, surgical ligation, and arterial bypass. In this case report, we present a patient with a stab wound to the axilla. Two years after the injury, a pseudoaneurysm developed in the left brachial artery. The pseudoaneurysm was treated with endovascular stent graft
{"title":"Closure of a pseudo aneurysm developed after trauma in the brachial artery with endovascular stent graft: A case report","authors":"B. Tamtekin, Güler Gülsen Ersoy, I. Dal","doi":"10.51271/kmj-0068","DOIUrl":"https://doi.org/10.51271/kmj-0068","url":null,"abstract":" \u0000Aneurysm is defined as 50% enlargement of the normal diameter of the artery. The most common cause of true aneurysms is atherosclerosis. Pseudoaneurysms, on the other hand, occur as a result of the blood leaking from the tear in the arterial wall forming a thrombus formation and surrounding it with a fibrous capsule. In pseudoaneurysms, blood pools in a closed area. However, they may enlarge and rupture in the late period. Treatment options are thrombin injection, endovascular graft implantation, surgical ligation, and arterial bypass. In this case report, we present a patient with a stab wound to the axilla. Two years after the injury, a pseudoaneurysm developed in the left brachial artery. The pseudoaneurysm was treated with endovascular stent graft","PeriodicalId":369732,"journal":{"name":"Kastamonu Medical Journal","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115856052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: Cohort studies have shown that syncope is one in four of the initial symptoms of acute pulmonary embolism. However, one in six patients who visit the emergency room for their first syncopal attack has acute pulmonary embolism. Additionally, the etiological relationship between acute pulmonary embolism and the possible prognostic impact of syncope on the early clinical course of a patient with acute pulmonary embolism remains unclear. Our research sought to detect the presence of pulmonary embolism and its contributing factors in syncope patients who were admitted to the emergency room. Material and Method: The study comprised 215 individuals who had syncope and were transported by ambulance to the emergency department between January 2020 and January 2021. The age bracket for inclusion was 18 to 75, and the presence of solitary syncope, regardless of its cause, was required. Additionally, there had to be no clinical signs of shock or hypotension, and/or absence of right ventricular dysfunction at presentation. Results: A total of 215 patients were included in the study. The mean age was 57 years and 64% of the patients were female. Pulmonary CT angiography was performed in 37 of the patients. Ventilation-perfusion examination was performed on 2 patients. Pulmonary embolism was confirmed in 14 patients, including a lower segment pulmonary embolism. Pulmonary embolism was diagnosed in 7 of 17 patients with no history of active cancer and a previous history of thromboembolism. The prevalence of pulmonary embolism was similar as predicted by the Wells score or Pulmonary Embolism Rule–Out Criteria in patients with low and moderate clinical probability. Conclusion: The results of this study confirm that pulmonary embolism is rarely found in patients admitted to the emergency department with syncope. Althoughpulmonary embolismshould be considered as a differential diagnosis, it does not need to be evaluated in all patients. Otherwise, assessment can lead to false positive results and overtreatment, thereby increasing adverse events and healthcare costs.
{"title":"Pulmonary embolism prevalence in syncope patients brought to the emergency room by ambulance","authors":"Şükrü Yorulmaz, İ. Çeli̇k","doi":"10.51271/kmj-0074","DOIUrl":"https://doi.org/10.51271/kmj-0074","url":null,"abstract":" \u0000Aim: Cohort studies have shown that syncope is one in four of the initial symptoms of acute pulmonary embolism. However, one in six patients who visit the emergency room for their first syncopal attack has acute pulmonary embolism. Additionally, the etiological relationship between acute pulmonary embolism and the possible prognostic impact of syncope on the early clinical course of a patient with acute pulmonary embolism remains unclear. Our research sought to detect the presence of pulmonary embolism and its contributing factors in syncope patients who were admitted to the emergency room.\u0000Material and Method: The study comprised 215 individuals who had syncope and were transported by ambulance to the emergency department between January 2020 and January 2021. The age bracket for inclusion was 18 to 75, and the presence of solitary syncope, regardless of its cause, was required. Additionally, there had to be no clinical signs of shock or hypotension, and/or absence of right ventricular dysfunction at presentation.\u0000Results: A total of 215 patients were included in the study. The mean age was 57 years and 64% of the patients were female. Pulmonary CT angiography was performed in 37 of the patients. Ventilation-perfusion examination was performed on 2 patients. Pulmonary embolism was confirmed in 14 patients, including a lower segment pulmonary embolism. Pulmonary embolism was diagnosed in 7 of 17 patients with no history of active cancer and a previous history of thromboembolism. The prevalence of pulmonary embolism was similar as predicted by the Wells score or Pulmonary Embolism Rule–Out Criteria in patients with low and moderate clinical probability.\u0000Conclusion: The results of this study confirm that pulmonary embolism is rarely found in patients admitted to the emergency department with syncope. Althoughpulmonary embolismshould be considered as a differential diagnosis, it does not need to be evaluated in all patients. Otherwise, assessment can lead to false positive results and overtreatment, thereby increasing adverse events and healthcare costs.","PeriodicalId":369732,"journal":{"name":"Kastamonu Medical Journal","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131254906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Asu Özgültekin, A. Karayel, Seher Yanatma, O. Ekinci
Background: With its important properties, Vitamin C has been used in several diseases and sepsis. COVID-19 may cause sepsis, and therefore high dose Vitamin C has been integrated to the treatment protocols.Concerning the potential risk of oxalate nephropaty related with the use of long term or high dose Vitamin C, we retrospectively evaluated the COVID-19 patients treated with the high dose intravenous Vitamin C, in terms of kidney dysfunction. Material and Method: Critically ill COVID-19 patients who were given Vitamin C 45-50 gr/day/5 days (Group C, n=21), and the ones who did not (Group NC, n=22) along with the hydroxychloroquine- favipiravir treatment were compared in terms of developing renal dysfunction within the 15 days of ICU stay. Results: There were no difference in the development of renal dysfunction between the groups with and without Vitamin C treatment (p>0.05). But when the patients who had KDIGO stage 1 kidney damage on admission, and had worsening renal dysfunction during ICU stay were excluded, patients groups were more similar and the development of the renal failure was significantly more in Vitamin C group(p<0.05). Conclusion: We conclude that when administering high dose parenteral Vitamin C, kidney functions should be carefully assessed.
背景:维生素C具有重要的特性，已被用于治疗多种疾病和败血症。COVID-19可能导致败血症，因此高剂量维生素C已被纳入治疗方案。针对长期或高剂量维生素C使用与草酸肾病的潜在风险，我们回顾性评估了高剂量静脉注射维生素C治疗的COVID-19患者的肾功能障碍。材料与方法:比较重症COVID-19患者在ICU住院15 d内，给予维生素C 45-50 gr/d /5 d (C组，n=21)与未给予维生素C 45-50 gr/d (NC组，n=22)并给予羟氯喹-法匹拉韦治疗的肾功能损害情况。结果:服用维生素C组与未服用维生素C组肾功能不全情况无显著差异(p>0.05)。但当排除入院时已发生KDIGO期肾损害、ICU住院期间肾功能恶化的患者时，患者组更相似，维生素C组肾功能衰竭的发生明显多于对照组(p<0.05)。结论:我们得出结论，在给予高剂量静脉注射维生素C时，应仔细评估肾功能。
{"title":"The effect of high-dose vitamin C on renal functions in COVID–19 patients","authors":"Asu Özgültekin, A. Karayel, Seher Yanatma, O. Ekinci","doi":"10.51271/kmj-0059","DOIUrl":"https://doi.org/10.51271/kmj-0059","url":null,"abstract":" \u0000Background: With its important properties, Vitamin C has been used in several diseases and sepsis. COVID-19 may cause sepsis, and therefore high dose Vitamin C has been integrated to the treatment protocols.Concerning the potential risk of oxalate nephropaty related with the use of long term or high dose Vitamin C, we retrospectively evaluated the COVID-19 patients treated with the high dose intravenous Vitamin C, in terms of kidney dysfunction.\u0000Material and Method: Critically ill COVID-19 patients who were given Vitamin C 45-50 gr/day/5 days (Group C, n=21), and the ones who did not (Group NC, n=22) along with the hydroxychloroquine- favipiravir treatment were compared in terms of developing renal dysfunction within the 15 days of ICU stay.\u0000Results: There were no difference in the development of renal dysfunction between the groups with and without Vitamin C treatment (p>0.05). But when the patients who had KDIGO stage 1 kidney damage on admission, and had worsening renal dysfunction during ICU stay were excluded, patients groups were more similar and the development of the renal failure was significantly more in Vitamin C group(p<0.05).\u0000Conclusion: We conclude that when administering high dose parenteral Vitamin C, kidney functions should be carefully assessed.","PeriodicalId":369732,"journal":{"name":"Kastamonu Medical Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127838980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ola Abuzaid, Şefika Akyol, Said Can Alcalı, Ekrem Ünal
Hemophagocytic lymphohistiocytosis should be considered in patients with persistent fever, hepatosplenomegaly, pancytopenia. Hypercytokinemia originated from genetic disorder effecting the cellular defects of cytotoxic T and natural killer lymphocyte activity is the underlying pathophysiology of the disorder. In this review we summarized the recent advances in the management of hemophagocytic lymphohistiocytosis.
{"title":"Hemophagocytic lymphohistiocytosis: pouring gasoline on the cytokine storm","authors":"Ola Abuzaid, Şefika Akyol, Said Can Alcalı, Ekrem Ünal","doi":"10.51271/kmj-0036","DOIUrl":"https://doi.org/10.51271/kmj-0036","url":null,"abstract":"Hemophagocytic lymphohistiocytosis should be considered in patients with persistent fever, hepatosplenomegaly, pancytopenia. Hypercytokinemia originated from genetic disorder effecting the cellular defects of cytotoxic T and natural killer lymphocyte activity is the underlying pathophysiology of the disorder. In this review we summarized the recent advances in the management of hemophagocytic lymphohistiocytosis.","PeriodicalId":369732,"journal":{"name":"Kastamonu Medical Journal","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123308979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Colchicine is used in the treatment of many diseases. It should be used very carefully as the treatment dose and toxic dose are very close to each other and may lead to multiorgan failure. Although colchicine toxicity is usually seen in suicidal use, it may also occur when used in therapeutic doses. In this report, we present a case of a 70-year-old patient who used colchicine due to pericardial effusion over two months and died from multiorgan failure, to draw attention to colchicine toxicity due to using it in therapeutic doses.
{"title":"Multiorgan dysfunction due to colchicine","authors":"Miraç Koç, Hatice Karabulut, Özgür Önen, F. Akyel, Fatma Mutlu Kukul Güven","doi":"10.51271/kmj-0042","DOIUrl":"https://doi.org/10.51271/kmj-0042","url":null,"abstract":"Colchicine is used in the treatment of many diseases. It should be used very carefully as the treatment dose and toxic dose are very close to each other and may lead to multiorgan failure. Although colchicine toxicity is usually seen in suicidal use, it may also occur when used in therapeutic doses. In this report, we present a case of a 70-year-old patient who used colchicine due to pericardial effusion over two months and died from multiorgan failure, to draw attention to colchicine toxicity due to using it in therapeutic doses.","PeriodicalId":369732,"journal":{"name":"Kastamonu Medical Journal","volume":"4 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114093780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Tamtekin, Güler Gülsen Ersoy, Nurcan Ayabakan Eski, I. Dal
Aim: The aim of this study is to evaluate the results of 67 open heart surgeries performed in the first year in a new cardiovascular surgery clinic.Material and Method: Patients who underwent open heart surgery in our clinic between May 2021 and May 2022 were evaluated retrospectively. The hospitalization time, cross-clamp time, complications and mortality data of the patients were obtained retrospectively from the hospital database. In the analysis of the data, mean values were calculated for continuous variables, while percentage and frequency values were shown for categorical variables.Results: A total of 67 cases were included in the study. Isolated CABG surgery was performed on 44 patients with cardiopulmonary bypass (CPB). Isolated CABG surgery was performed on 3 patients without CPB (beating heart). CABG and mitral valve replacement (MVR) operations were performed simultaneously in two patients. MVR operation and tricuspid valve annuloplasty operations were performed simultaneously in two patients. MVR surgery was performed in four patients in isolation. Aortic valve replacement (AVR) operation was performed in 6 patients in isolation. Ascending aorta replacement was performed in three patients simultaneously with AVR operation. Bentall surgery was performed in two patients, and intra-cardiac tumor (myxoma) excision surgery was performed in one patient. Bleeding revision surgery was performed in one patient (1.5%) on the same day due to early bleeding and pericardial tamponade. Sternal dehiscence was observed in two patients in the late period (3%). Postoperative mortality was seen in a total of four patients (5.9%).Conclusion: As a result of our study, we determined that the surgeries performed in our newly opened cardiovascular clinic may have similar results to experienced clinics in terms of mortality and morbidity.
{"title":"A new heart surgery clinic: results of 67 open heart surgery in the first year","authors":"B. Tamtekin, Güler Gülsen Ersoy, Nurcan Ayabakan Eski, I. Dal","doi":"10.51271/kmj-0040","DOIUrl":"https://doi.org/10.51271/kmj-0040","url":null,"abstract":"Aim: The aim of this study is to evaluate the results of 67 open heart surgeries performed in the first year in a new cardiovascular surgery clinic.Material and Method: Patients who underwent open heart surgery in our clinic between May 2021 and May 2022 were evaluated retrospectively. The hospitalization time, cross-clamp time, complications and mortality data of the patients were obtained retrospectively from the hospital database. In the analysis of the data, mean values were calculated for continuous variables, while percentage and frequency values were shown for categorical variables.Results: A total of 67 cases were included in the study. Isolated CABG surgery was performed on 44 patients with cardiopulmonary bypass (CPB). Isolated CABG surgery was performed on 3 patients without CPB (beating heart). CABG and mitral valve replacement (MVR) operations were performed simultaneously in two patients. MVR operation and tricuspid valve annuloplasty operations were performed simultaneously in two patients. MVR surgery was performed in four patients in isolation. Aortic valve replacement (AVR) operation was performed in 6 patients in isolation. Ascending aorta replacement was performed in three patients simultaneously with AVR operation. Bentall surgery was performed in two patients, and intra-cardiac tumor (myxoma) excision surgery was performed in one patient. Bleeding revision surgery was performed in one patient (1.5%) on the same day due to early bleeding and pericardial tamponade. Sternal dehiscence was observed in two patients in the late period (3%). Postoperative mortality was seen in a total of four patients (5.9%).Conclusion: As a result of our study, we determined that the surgeries performed in our newly opened cardiovascular clinic may have similar results to experienced clinics in terms of mortality and morbidity.","PeriodicalId":369732,"journal":{"name":"Kastamonu Medical Journal","volume":"128 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130468391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Deniz İncaman, Rumeysa Çolak, M. Çınar, A. Çalışır
Aim: Coronavirus disease is the third coronavirus infection defined in the world in the 21st century, after severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS).Material and Method: We planned to evaluate demographic characteristics retrospectively and present them to the literature with statistical data. The patients included in our study, positive PCR ( polymerase chain reaction) test, who is under treatment in the COVID-19 intensive care units of our hospital due to COVID-19 disease. Age, comorbid conditions, admission complaints, physical examination findings, acute phase reactants, tomography results, length of hospital stay, and treatments of these patients were scanned from the patient files.Results: Demographic characteristics were found to be similar to the literature, but there is not enough data in the literature about chronic drug use. Elderly age, cardiovascular diseases, and ıntensive care unit hospitalization were associated with mortality.Conclusion: The patient group who has a chronic disease and uses multiple drugs should be considered. We think that we contribute to the literature with this information in our study.
{"title":"Demographic features of patients followed up in COVID intensive care units during the pandemic period","authors":"Deniz İncaman, Rumeysa Çolak, M. Çınar, A. Çalışır","doi":"10.51271/kmj-0038","DOIUrl":"https://doi.org/10.51271/kmj-0038","url":null,"abstract":"Aim: Coronavirus disease is the third coronavirus infection defined in the world in the 21st century, after severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS).Material and Method: We planned to evaluate demographic characteristics retrospectively and present them to the literature with statistical data. The patients included in our study, positive PCR ( polymerase chain reaction) test, who is under treatment in the COVID-19 intensive care units of our hospital due to COVID-19 disease. Age, comorbid conditions, admission complaints, physical examination findings, acute phase reactants, tomography results, length of hospital stay, and treatments of these patients were scanned from the patient files.Results: Demographic characteristics were found to be similar to the literature, but there is not enough data in the literature about chronic drug use. Elderly age, cardiovascular diseases, and ıntensive care unit hospitalization were associated with mortality.Conclusion: The patient group who has a chronic disease and uses multiple drugs should be considered. We think that we contribute to the literature with this information in our study.","PeriodicalId":369732,"journal":{"name":"Kastamonu Medical Journal","volume":"132 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131579849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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