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The assessment of plantar pressure distribution in plantar fasciitis and its relationship with treatment success and fascial thickness 足底筋膜炎患者足底压力分布的评估及其与治疗成功和筋膜厚度的关系
Pub Date : 2023-09-22 DOI: 10.51271/kmj-0114
Aslıhan Ulusoy, Lale Cerrahoğlu, Şebnem Örgüç
Aim: Patients with plantar fasciitis modify their gait patterns due to the heel pain. We aimed to investigate whether there was a significant difference in the plantar pressure distribution after pain relief due to successful treatment response in plantar fasciitis. Methods: 49 patients diagnosed with chronic unilateral plantar fasciitis received a 3-week physical therapy intervention and home exercises. Visual analog scale, plantar pressure measurement by pedobarographic assessment and magnetic resonance imaging were performed before and 1 month after the intervention. At the 1-month follow up, participants were divided into 2 groups according to successful or poor response to treatment. The treatment's success criteria was defined as a percentage decrease in heel pain exceeding 60% compared to the baseline, assessed one month after the initiation of treatment. Results: A total of 44 subjects successfully completed the study. In group 1, characterized by successful responders, there were 24 subjects, while group 2, comprising poor responders, included 20 subjects. After treatment in group 1, the dynamic plantar pressure on the medial forefoot showed a significant increase (p = 0.015). However, there was no significant change in plantar pressure in the poor responders. Plantar fascia thickness correlated positively with thumb dynamic pressures (coronal p = 0.03 r = 0.434, sagittal r = 0.451 p = 0.02). Conclusion: The results suggest that fascial thickness and dynamic forefoot plantar pressures may be related. Medial forefoot plantar pressures increased as a result of gait restoration with significant pain reduction in adults.
目的:足底筋膜炎患者改变他们的步态模式,由于足跟疼痛。我们的目的是研究足底筋膜炎成功治疗后疼痛缓解后足底压力分布是否有显著差异。方法:对49例慢性单侧足底筋膜炎患者进行为期3周的物理治疗干预和家庭锻炼。在干预前和干预后1个月分别进行视觉模拟量表、足底压力测量、足压评估和磁共振成像。随访1个月,根据治疗效果好坏分为两组。治疗的成功标准定义为治疗开始一个月后,与基线相比,足跟疼痛减少的百分比超过60%。结果:44名受试者成功完成研究。第一组以成功应答者为特征,有24名受试者;第二组以不良应答者为特征,有20名受试者。1组治疗后,前足内侧的动态足底压力显著增加(p = 0.015)。然而,反应不良的患者足底压力无明显变化。足底筋膜厚度与拇指动压呈正相关(冠状面p = 0.03 r = 0.434,矢状面r = 0.451 p = 0.02)。结论:筋膜厚度与动态前足足底压力有关。在成人中,由于步态恢复和显著的疼痛减轻,内侧前足足底压力增加。
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引用次数: 0
Evaluation of drug use in patients over 65 years of age admitted to endocrinology outpatient clinic with beers criteria 65岁以上内分泌科门诊患者用药评价
Pub Date : 2023-06-26 DOI: 10.51271/kmj-0104
Sinem Gürcü, A. Kalkan
Aims: Multiple drug use creates a burden on both the individual and the health system. And this is often observed in advanced age patient groups. Various scales have been developed for the prevention of polypharmacy. We aimed to apply the Beers criteria used for this purpose in the prescriptions of patients who applied to the endocrinology outpatient clinic.Methods: 102 patients aged 65 years and over who applied to the endocrinology outpatient clinic for routine control and who had at least four drugs in their prescription were included in this study. Demographic data and drug use status of the patients were recorded and evaluated.Results: Of the 102 cases included in the study, 70 (68.6%) were women. The most common chronic pathology was diabetesmellitus in 83 (81.4%) cases. Inappropriate drug use was most common in endocrine system drugs. The prescriptions included in the study were evaluated according to the 2019 Beers criteria retrospectively and inappropriate drug use was detected in 42 prescriptions (41.2%).Conclusion: Considering the pharmacodynamic and pharmacokinetic properties of drugs that change with age, theimportance of polypharmacy and inappropriate drug use has emerged, and standardized scales have been created to evaluate this situation in elderly patients. In this study, insulins, proton pump inhibitors, and non-steroidal anti-inflammatory drugs seem to be the most commonly administered inappropriate drugs. Applying Beers criteria, one of the polypharmacy scales may be the right approach for a rational and effective treatment in the elderly.
目的:多种药物使用对个人和卫生系统都造成负担。这在老年患者群体中经常观察到。为了预防多药,已经开发了各种量表。我们的目的是应用比尔斯标准用于这一目的的处方患者谁申请内分泌门诊诊所。方法:选取102例65岁及以上在内分泌科门诊进行常规对照且处方中至少有4种药物的患者作为研究对象。对患者的人口统计资料和用药情况进行记录和评价。结果:纳入研究的102例患者中,70例(68.6%)为女性。83例(81.4%)慢性病理以糖尿病为主。用药不当以内分泌系统类药物最为常见。按照2019年Beers标准对纳入研究的处方进行回顾性评价,发现42张处方(41.2%)存在用药不当。结论:考虑到药物的药效学和药代动力学特性随年龄的变化而变化,多重用药和不当用药的重要性已经显现出来,并建立了标准化的量表来评价老年患者的这种情况。在这项研究中,胰岛素、质子泵抑制剂和非甾体抗炎药似乎是最常见的不合适的药物。应用比尔斯标准,其中一种多药量表可能是合理有效治疗老年人的正确方法。
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引用次数: 0
Determination of hepatitis B and hepatitis C seroprevalence in pregnant women in the Kastamonu region, Turkey 土耳其Kastamonu地区孕妇乙型和丙型肝炎血清阳性率测定
Pub Date : 2023-06-26 DOI: 10.51271/kmj-0103
Enis Fuat Tüfekci, B. Çalışır, Melike Yaşar Duman, Ç. Kılınç
Aims: Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections during pregnancy have a risk of transmission to thenewborn. Therefore, pregnant women are routinely screened for HBV and HCV in many countries. This study aimed to reveal the seroprevalence of HBsAg, anti-HBs, and anti-HCV in pregnant women in the Kastamonu region and to compare the obtained data with the results of studies conducted in Turkey.Methods: Pregnant women who applied to Kastamonu Training and Research Hospital Microbiology laboratory betweenJanuary 2022 and January 2023 for HBsAg, anti-HBs, and anti-HCV tests were included in this study. The pregnant womenwere separated into two groups ?24 and >24 age groups. The tests were performed using the chemiluminescence microparticle immune assay method on the Abbott Architect i2000SR instrument, and the results were evaluated per the manufacturer’s instructions.Results: HBsAg, anti-HBs, and anti-HCV positivity were 0.5% (n=9/1712), 51.1% (n=874/1712), and 0.1% (n=2/1713),respectively. While there was no significant difference between age groups for HBsAg positivity (p>0.05), anti-HBs positivitywas found to be significantly higher in the ?24 age group than in the >24 age group (p=0.002).Conclusion: The results showed that HBsAg and anti-HCV positivity was lower than in most studies conducted in recent years in Turkey, and anti-HBs positivity was higher than in most studies. It is essential to continue routine HBV and HCV screening in pregnant women’s first follow-up and encourage anti-HBs-negative individuals to be vaccinated against HBV.
目的:怀孕期间乙型肝炎病毒(HBV)和丙型肝炎病毒(HCV)感染有传播给新生儿的风险。因此,在许多国家对孕妇进行了常规的乙肝和丙肝筛查。本研究旨在揭示Kastamonu地区孕妇血清中HBsAg、anti-HBs和anti-HCV的患病率,并将获得的数据与土耳其进行的研究结果进行比较。方法:选取2022年1月至2023年1月期间到Kastamonu培训研究医院微生物实验室进行HBsAg、anti-HBs和anti-HCV检测的孕妇为研究对象。这些孕妇被分成两组,分别是24岁和24岁。在雅培Architect i2000SR仪器上使用化学发光微粒免疫分析法进行测试,并根据制造商的说明对结果进行评估。结果:HBsAg、anti-HBs和anti-HCV阳性率分别为0.5% (n=9/1712)、51.1% (n=874/1712)和0.1% (n=2/1713)。HBsAg阳性在不同年龄组间无显著差异(p < 0.05),而抗- hbbs阳性在24岁年龄组明显高于24岁年龄组(p < 0.002)。结论:结果显示,HBsAg和anti-HCV阳性率低于土耳其近年来的大多数研究,而anti-HBs阳性率高于大多数研究。在孕妇的第一次随访中继续进行常规HBV和HCV筛查是至关重要的,并鼓励抗hbs阴性的个体接种HBV疫苗。
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引用次数: 0
Verifiying gastric tube placement using neck ultrasonography in mechanically ventilated patients in the intensive care unit 重症监护室机械通气患者颈部超声检查胃管放置的验证
Pub Date : 2023-06-26 DOI: 10.51271/kmj-0100
M. Dağdelen, İ. Ceylan, F. Kahveci
Aims: This study aimed to compare neck ultrasonography to chest X-ray—the gold standard technique—to evaluate the effectiveness in verifying gastric tube placement.Methods: This prospective study reported the data of the 39 mechanically ventilated patients in the intensive care unit. While inserting the gastric tube, a linear ultrasound probe was simultaneously used to visualize the esophagus in the left lateral region of the neck, and obscuration of the posterior esophageal wall was observed during passage of the tube. In addition, ultrasonography was used to detect “dynamic fogging” in the stomach, while auscultation was also used to determine the location of the tube. Chest X-ray images were captured from all patients included in the study.Results: Among 39 patients who had been enrolled in the study, three of them died before chest X-ray, the esophagus could not be visualized in 9 and the stomach could not be visualized in 4 using ultrasonography. The sensitivity, specificity, positive predictive value, negative predictive value of neck ultrasonography in verifying gastric tube placement were 69.7%, 66.7%, 95.8% and 16.7%, respectively and, 51.5%, 100%, 100% and 15.7%, respectively, for stomach ultrasonography.Conclusion: Visualization of gastric tube insertion in the esophagus using neck ultrasonography demonstrated various advantages including non-invasiveness, rapidity, and bedside technique availability, although it has lower sensitivity and specificity due to its operator-dependent nature.
目的:本研究旨在比较颈部超声检查与胸部x线检查(金标准技术)对验证胃管放置的有效性。方法:本前瞻性研究报告重症监护病房39例机械通气患者的资料。在插入胃管的同时,使用线性超声探头显示颈部左侧食道,在胃管通过过程中观察到食管后壁的遮挡。此外,超声检查胃内“动态雾化”,听诊也用于确定管的位置。研究中所有患者的胸部x线图像均被采集。结果:纳入研究的39例患者中,有3例在胸部x线检查前死亡,9例食管不能显示,4例胃不能显示。颈部超声对验证胃管放置的敏感性、特异性、阳性预测值、阴性预测值分别为69.7%、66.7%、95.8%、16.7%;胃超声对验证胃管放置的敏感性、特异性、阳性预测值、阴性预测值分别为51.5%、100%、100%、15.7%。结论:颈部超声显示食管胃管插入具有无创、快速、床边技术可用性等优点,但由于其依赖于操作者,敏感性和特异性较低。
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引用次数: 0
The effect of prolonged intubation on ventilator associated pneumonia: endotracheal tube cuff is really steril or not? 延长插管对呼吸机相关性肺炎的影响:气管插管袖口是否真的无菌?
Pub Date : 2023-06-26 DOI: 10.51271/kmj-0099
D. Özdemir, S. Görgün, A. Çeçen, S. Alkan, Yavuz Çeçen, D. M. Mehel, Asude Ünal
Aims: Endotracheal tube (ETT) design, size, cuff material, cuff pressure, and intubation duration are critical in preventing nosocomial pneumonia. We aimed to evaluate the possible infection focus potential of ETT cuff and pilot balloon, particularly in prolonged intubated patients.Methods: A total number of 66 patients who underwent orotracheal intubation and received conventional mechanical ventilation more than 48 hours in the intensive care unit (ICU), were included in this prospective cohort study.Results:The mean duration of intubation was 10.36±4.82 days. Bacteriologically confirmed positive tracheal aspirate culture was 18.2% (n=12). The most frequent positive culture was detected inside of ETT lumen with a percentage of 83.3% (n=55) and followed by cuff (27.3%, n=18), pilot balloon (13.6%, n=9), respectively. It was documented that rates of lung infections were significantly increased after 14 days (p = 0.017) and rates of cuff positive cultures were significantly increased after 10 and 14 days of incubation (p= 0.001, p=0.004). The same type of bacteriological strains was identified from both pilot balloon (n=9) and ETT cuff (n=9), simultaneously. In the remaining 9-cuff positive patients pilot balloons were sterile and ETT lumens were positive culture with the same strains as identified from the cuff. There was a statistically significant positive correlation between the intubation duration and the number of infected ETT parts (p<0.001).Conclusion: ETT cuff was demonstrated to be a potential infection focus in the present study. In addition, it was observed that ETT cuff colonization increased in proportion to the intubation duration. We suggest changing ETT at appropriate time intervals in order to reduce ventilator-associated pneumonia in intubated patients.
目的:气管插管(ETT)的设计、尺寸、袖带材料、袖带压力和插管时间对预防院内肺炎至关重要。我们的目的是评估ETT袖带和导球囊可能的感染焦点潜力,特别是在长时间插管的患者中。方法:本前瞻性队列研究纳入重症监护病房(ICU)经口气管插管并接受常规机械通气超过48小时的患者66例。结果:平均插管时间为10.36±4.82 d。细菌学证实气管吸入培养阳性为18.2% (n=12)。最常见的阳性培养是ETT管腔内,占83.3% (n=55),其次是袖带(27.3%,n=18)和气囊(13.6%,n=9)。结果显示,14天后肺部感染率显著增加(p= 0.017), 10天和14天后袖带阳性培养率显著增加(p= 0.001, p=0.004)。同时从导球囊(n=9)和ETT袖口(n=9)中鉴定出相同类型的细菌菌株。在其余9例袖带阳性患者中,导球无菌,ETT管腔阳性培养,与袖带鉴定的菌株相同。插管时间与ETT感染件数呈显著正相关(p<0.001)。结论:ETT袖口是一种潜在的感染灶。此外,观察到ETT袖套定殖与插管时间成比例增加。我们建议在适当的时间间隔改变ETT,以减少插管患者的呼吸机相关性肺炎。
{"title":"The effect of prolonged intubation on ventilator associated pneumonia: endotracheal tube cuff is really steril or not?","authors":"D. Özdemir, S. Görgün, A. Çeçen, S. Alkan, Yavuz Çeçen, D. M. Mehel, Asude Ünal","doi":"10.51271/kmj-0099","DOIUrl":"https://doi.org/10.51271/kmj-0099","url":null,"abstract":"Aims: Endotracheal tube (ETT) design, size, cuff material, cuff pressure, and intubation duration are critical in preventing nosocomial pneumonia. We aimed to evaluate the possible infection focus potential of ETT cuff and pilot balloon, particularly in prolonged intubated patients.\u0000Methods: A total number of 66 patients who underwent orotracheal intubation and received conventional mechanical ventilation more than 48 hours in the intensive care unit (ICU), were included in this prospective cohort study.\u0000Results:The mean duration of intubation was 10.36±4.82 days. Bacteriologically confirmed positive tracheal aspirate culture was 18.2% (n=12). The most frequent positive culture was detected inside of ETT lumen with a percentage of 83.3% (n=55) and followed by cuff (27.3%, n=18), pilot balloon (13.6%, n=9), respectively. It was documented that rates of lung infections were significantly increased after 14 days (p = 0.017) and rates of cuff positive cultures were significantly increased after 10 and 14 days of incubation (p= 0.001, p=0.004). The same type of bacteriological strains was identified from both pilot balloon (n=9) and ETT cuff (n=9), simultaneously. In the remaining 9-cuff positive patients pilot balloons were sterile and ETT lumens were positive culture with the same strains as identified from the cuff. There was a statistically significant positive correlation between the intubation duration and the number of infected ETT parts (p<0.001).\u0000Conclusion: ETT cuff was demonstrated to be a potential infection focus in the present study. In addition, it was observed that ETT cuff colonization increased in proportion to the intubation duration. We suggest changing ETT at appropriate time intervals in order to reduce ventilator-associated pneumonia in intubated patients.","PeriodicalId":369732,"journal":{"name":"Kastamonu Medical Journal","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122922288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Splenic artery aneurysm rupture after using enoxaparin for COVID-19: is it a coincidence or complication? 依诺肝素治疗COVID-19后脾动脉瘤破裂:是巧合还是并发症?
Pub Date : 2023-06-26 DOI: 10.51271/kmj-0109
Özgür Önen, Y. Yıldız, Miraç Koç, Fatma Mutlu Kukul Güven
Splenic artery aneurysm is a rare and usually asymptomatic disease that is more common among women. It is usually diagnosed as a result of rupture during pregnancy. It may result in mortality if patients with rupture are not diagnosed and treated early. Although the endovascular method is the first choice in treatment, the surgical procedure can also be applied in hemodynamically unstable patients. In this report, we present a case of splenic artery aneurysm rupture that occurred due to the use of enoxaparin in a patient diagnosed with COVID-19 and followed up at home.
脾动脉瘤是一种罕见且通常无症状的疾病,多见于女性。它通常被诊断为怀孕期间破裂的结果。如果破裂患者不及早诊断和治疗,可能会导致死亡。虽然血管内方法是治疗的首选,但手术也可以应用于血流动力学不稳定的患者。在本报告中,我们报告了一例因使用依诺肝素而发生脾动脉瘤破裂的病例,该病例被诊断为COVID-19并在家中随访。
{"title":"Splenic artery aneurysm rupture after using enoxaparin for COVID-19: is it a coincidence or complication?","authors":"Özgür Önen, Y. Yıldız, Miraç Koç, Fatma Mutlu Kukul Güven","doi":"10.51271/kmj-0109","DOIUrl":"https://doi.org/10.51271/kmj-0109","url":null,"abstract":"Splenic artery aneurysm is a rare and usually asymptomatic disease that is more common among women. It is usually diagnosed as a result of rupture during pregnancy. It may result in mortality if patients with rupture are not diagnosed and treated early. Although the endovascular method is the first choice in treatment, the surgical procedure can also be applied in hemodynamically unstable patients. In this report, we present a case of splenic artery aneurysm rupture that occurred due to the use of enoxaparin in a patient diagnosed with COVID-19 and followed up at home.","PeriodicalId":369732,"journal":{"name":"Kastamonu Medical Journal","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116456296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of brain computed tomography results in pediatric traumas 评估脑计算机断层扫描结果在儿童创伤
Pub Date : 2023-06-26 DOI: 10.51271/kmj-0106
Ertan Cömertpay, Sinan Oğuzhan Özsan, Ömer Yeşilyurt, O. Eroğlu, S. Vural, F. Coşkun
Aims: The use of brain computed tomography (CT) in the management of childhood head traumas is increasing everyday. However, due to the more prominent harmful effects of radiation caused by CT in children and the increase in healthexpenditures, rules have been settled to determine brain CT indications, especially in children with mild head trauma. The aim of this study is to contribute to the literature by sharing the demographic characteristics, clinical findings and Brain CT results of pediatric patients who admitted to the emergency department (ED) with head trauma.Methods: The study was conducted retrospectively in children who admitted to Kırıkkale University Hospital ED withhead trauma. The demographic characteristics of the patients, their complaints at admission, Glasgow coma score (GCS),examination findings, follow-up and treatment management in the ED, and brain CT results were recorded. Chi-square testwas used to compare the data. A value of p<0.05 was considered statistically significant.Results: 234 children with head trauma were included in the study. Mean age of the study group was: 9.13±6.36 /years and57.3% (n=134) were males. While 7.2% of the children were <2 years old, 92.8% of them were ?2 years old. Mean GCS was14.92±0.79. Falling from a height was the most common cause of head trauma with 30.8%, followed by falling from the same level with 21.8% and in-vehicle traffic accident with 18.4%. Headache (37.2%), nausea-vomiting (36.8%) and loss of consciousness (13.7%) were the three most common admission symptoms after head trauma. Headache was found to be significantly higher in the ?2 age group and nausea-vomiting in the <2 age group compared to the other group (p=0.006; p<0.001, respectively). While 97.9% of brain CT results were normal, the most common pathological finding was linear fracture (2.1%). In terms of brain CT results, no difference was found between children <2 years and ?2 years of age (p=0.527).Conclusion: Majority of the pediatric patients we evaluated in our study had minor head trauma, and most of the brain CTresults were normal. Headache, nausea, vomiting, and loss of consciousness were the three most common symptoms after head trauma. Nausea-vomiting was observed more frequently in children aged <2 years and headache was observed inchildren aged ?2 years after head trauma, compared to other age groups.
目的:脑计算机断层扫描(CT)在儿童颅脑外伤治疗中的应用日益增多。然而,由于CT对儿童造成的辐射危害更加突出以及医疗支出的增加,人们已经制定了确定脑CT适应症的规则,特别是在轻度头部创伤的儿童中。本研究的目的是通过分享急诊科(ED)收治的头部创伤儿童患者的人口学特征、临床表现和脑CT结果,为文献做出贡献。方法:回顾性分析Kırıkkale大学医院急诊科收治的头部外伤患儿。记录患者的人口学特征、入院时的主诉、格拉斯哥昏迷评分(GCS)、检查结果、急诊科随访和治疗管理以及脑CT结果。数据比较采用卡方检验。p<0.05为差异有统计学意义。结果:共纳入234例颅脑外伤患儿。研究组平均年龄为:9.13±6.36岁,男性占57.3% (n=134)。2岁以下儿童占7.2%,2岁以下儿童占92.8%。平均GCS为14.92±0.79。从高处坠落是导致头部外伤最常见的原因,占30.8%,其次是从同一高度坠落,占21.8%,车内交通事故占18.4%。头痛(37.2%)、恶心呕吐(36.8%)和意识丧失(13.7%)是颅脑外伤后最常见的入院症状。2岁以下年龄组的头痛和<2岁以下年龄组的恶心呕吐发生率明显高于其他组(p=0.006;分别为p < 0.001)。97.9%的脑CT结果正常,最常见的病理表现为线状骨折(2.1%)。在脑CT结果方面,<2岁和?2岁儿童无差异(p=0.527)。结论:在我们的研究中,我们评估的大多数儿童患者都有轻微的头部创伤,大多数脑部ct结果正常。头痛、恶心、呕吐和意识丧失是头部外伤后最常见的三种症状。与其他年龄组相比,2岁以下儿童出现恶心呕吐的频率更高,2岁以下儿童出现头痛的频率更高。
{"title":"Evaluation of brain computed tomography results in pediatric traumas","authors":"Ertan Cömertpay, Sinan Oğuzhan Özsan, Ömer Yeşilyurt, O. Eroğlu, S. Vural, F. Coşkun","doi":"10.51271/kmj-0106","DOIUrl":"https://doi.org/10.51271/kmj-0106","url":null,"abstract":"Aims: The use of brain computed tomography (CT) in the management of childhood head traumas is increasing every\u0000day. However, due to the more prominent harmful effects of radiation caused by CT in children and the increase in health\u0000expenditures, rules have been settled to determine brain CT indications, especially in children with mild head trauma. The aim of this study is to contribute to the literature by sharing the demographic characteristics, clinical findings and Brain CT results of pediatric patients who admitted to the emergency department (ED) with head trauma.\u0000Methods: The study was conducted retrospectively in children who admitted to Kırıkkale University Hospital ED with\u0000head trauma. The demographic characteristics of the patients, their complaints at admission, Glasgow coma score (GCS),\u0000examination findings, follow-up and treatment management in the ED, and brain CT results were recorded. Chi-square test\u0000was used to compare the data. A value of p<0.05 was considered statistically significant.\u0000Results: 234 children with head trauma were included in the study. Mean age of the study group was: 9.13±6.36 /years and\u000057.3% (n=134) were males. While 7.2% of the children were <2 years old, 92.8% of them were ?2 years old. Mean GCS was\u000014.92±0.79. Falling from a height was the most common cause of head trauma with 30.8%, followed by falling from the same level with 21.8% and in-vehicle traffic accident with 18.4%. Headache (37.2%), nausea-vomiting (36.8%) and loss of consciousness (13.7%) were the three most common admission symptoms after head trauma. Headache was found to be significantly higher in the ?2 age group and nausea-vomiting in the <2 age group compared to the other group (p=0.006; p<0.001, respectively). While 97.9% of brain CT results were normal, the most common pathological finding was linear fracture (2.1%). In terms of brain CT results, no difference was found between children <2 years and ?2 years of age (p=0.527).\u0000Conclusion: Majority of the pediatric patients we evaluated in our study had minor head trauma, and most of the brain CT\u0000results were normal. Headache, nausea, vomiting, and loss of consciousness were the three most common symptoms after head trauma. Nausea-vomiting was observed more frequently in children aged <2 years and headache was observed inchildren aged ?2 years after head trauma, compared to other age groups.","PeriodicalId":369732,"journal":{"name":"Kastamonu Medical Journal","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131171503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of perinephric fat stranding with CT severity scores and mortality in COVID-19 patients COVID-19患者肾周脂肪滞留与CT严重程度评分和死亡率的关系
Pub Date : 2023-06-26 DOI: 10.51271/kmj-0105
Burcu Akman, A. Kaya
Aims: To investigate the relationship between the presence of perinephric fat stranding (PFS) with three consecutive chest CT severity scores (CT-SS), mortality and intensive care unit admission in COVID-19 patients. Methods: This single-center retrospective study, included 457 (?18 years) COVID-19 patients with positive RT-PCR tests. A radiologist calculated three consecutive CT-SS for COVID-19 pneumonia using a visual scoring system ranging from 0 to 25 points. Grades of PFS on CTs were defined as none, mild, moderate or severe. Firstly, patients were divided into two groups, with and without PFS. The Association of PFS with demographic and laboratory data, CT-SS, and mortality rates were analyzed. We divided patients into four subgroups based on PFS grading and investigated temporal changes of mean CT-SS of three consecutive CTs in each PFS subgroup using a paired-sample test and Wilcoxon signed-rank test.Results: Patients with PFS were associated with older age (p<0.001) and had higher CT-SS (p=0.03). We found a particularly strong association between PFS and mortality (p<0.001) and intensive care unit admission (p=0.001). Statistical associations were found between PFS and elevated serum BUN (p=0.004), creatinine (p=0.007), CRP (p=0.02), and ferritin (p=0.005). In multivariate logistic regression analysis, older age was associated with 1.067-fold (p<=0.001), PFS 1.964-fold (p=0.007), elevated serum creatinine 3.630-fold (p=0.005) higher risks of mortality. In PFS subgroups other than severe, there were significant increases between the first and second CT-SS (p<0.001, p<0.001, p=0.003).Conclusion: Perinephric fat stranding is an important CT finding that can alert clinicians to the poor prognosis of COVID-19 patients in early periods.
目的:探讨COVID-19患者肾周脂肪搁浅(PFS)的存在与连续三次胸部CT严重程度评分(CT- ss)、死亡率和重症监护病房入住的关系。方法:本单中心回顾性研究纳入457例(?18岁)RT-PCR检测阳性的COVID-19患者。放射科医生使用0 ~ 25分的视觉评分系统,连续3次计算出COVID-19肺炎的CT-SS。ct上PFS的等级定义为无、轻度、中度和重度。首先将患者分为有PFS组和无PFS组。分析PFS与人口学和实验室数据、CT-SS和死亡率的关系。我们根据PFS分级将患者分为4个亚组,并使用配对样本检验和Wilcoxon符号秩检验研究每个PFS亚组连续3次ct的平均CT-SS的时间变化。结果:PFS患者与年龄相关(p<0.001), CT-SS较高(p=0.03)。我们发现PFS与死亡率(p<0.001)和重症监护病房入住(p=0.001)之间存在特别强的关联。PFS与血清BUN (p=0.004)、肌酐(p=0.007)、CRP (p=0.02)、铁蛋白(p=0.005)升高有统计学关联。多因素logistic回归分析显示,年龄越大,死亡风险增加1.067倍(p<=0.001), PFS升高1.964倍(p=0.007),血清肌酐升高3.630倍(p=0.005)。在非严重PFS亚组中,第一次和第二次CT-SS评分显著增加(p<0.001, p<0.001, p=0.003)。结论:肾周脂肪搁浅是一项重要的CT发现,可以早期提醒临床医生COVID-19患者预后不良。
{"title":"Association of perinephric fat stranding with CT severity scores and mortality in COVID-19 patients","authors":"Burcu Akman, A. Kaya","doi":"10.51271/kmj-0105","DOIUrl":"https://doi.org/10.51271/kmj-0105","url":null,"abstract":"Aims: To investigate the relationship between the presence of perinephric fat stranding (PFS) with three consecutive chest CT severity scores (CT-SS), mortality and intensive care unit admission in COVID-19 patients. \u0000Methods: This single-center retrospective study, included 457 (?18 years) COVID-19 patients with positive RT-PCR tests. A radiologist calculated three consecutive CT-SS for COVID-19 pneumonia using a visual scoring system ranging from 0 to 25 points. Grades of PFS on CTs were defined as none, mild, moderate or severe. Firstly, patients were divided into two groups, with and without PFS. The Association of PFS with demographic and laboratory data, CT-SS, and mortality rates were analyzed. We divided patients into four subgroups based on PFS grading and investigated temporal changes of mean CT-SS of three consecutive CTs in each PFS subgroup using a paired-sample test and Wilcoxon signed-rank test.\u0000Results: Patients with PFS were associated with older age (p<0.001) and had higher CT-SS (p=0.03). We found a particularly strong association between PFS and mortality (p<0.001) and intensive care unit admission (p=0.001). Statistical associations were found between PFS and elevated serum BUN (p=0.004), creatinine (p=0.007), CRP (p=0.02), and ferritin (p=0.005). In multivariate logistic regression analysis, older age was associated with 1.067-fold (p<=0.001), PFS 1.964-fold (p=0.007), elevated serum creatinine 3.630-fold (p=0.005) higher risks of mortality. In PFS subgroups other than severe, there were significant increases between the first and second CT-SS (p<0.001, p<0.001, p=0.003).\u0000Conclusion: Perinephric fat stranding is an important CT finding that can alert clinicians to the poor prognosis of COVID-19 patients in early periods.\u0000","PeriodicalId":369732,"journal":{"name":"Kastamonu Medical Journal","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123964752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ceftazidime/avibactam experience in tertiary hospital in Türkiye 头孢他啶/阿维巴坦在泰国三级医院的应用经验
Pub Date : 2023-06-26 DOI: 10.51271/kmj-0101
Alper Tahmaz, Ayşegül Şeremet Keskin
Aims: Real-life experience with ceftazidime/avibactam in the treatment of multidrug-resistant Klebsiella pneumoniae is still limited. This retrospective study aims to evaluate the efficacy of ceftazidime/avibactam in the treatment of critically ill patients with infections due to carbapenem-resistant pathogens.Methods: In our study, patients who were hospitalized in the ICUs of our hospital for more than three days between 01-01-2022 and 31-12-2022, who had only ceftazidime/avibactam susceptibility growth and were started on ceftazidime/avibactam treatment were retrospectively analyzed. 38 patients older than 18 years of age were included in the study.Results: Pneumonia was the most common cause of hospitalization in the ICU, followed by cerebrovascular events and internal diseases, respectively. The mean time from taking the culture samples to obtaining the laboratory results was 4.6 ±1.46 days. After the culture result was confirmed by the laboratory, the mean time between the patient's consultation by infection diseases specialist and initiation of treatment was 1.7±1.3 days. Patients received a mean of 10.6 ±4.63 days of CAZ-AVI treatment as monotherapy (57.9%) or combined therapy (42.1). Clinical response was obtained in 52.6% of the patients, and microbiological response was obtained in 63.2% of the patients. The 90-day all-cause mortality rate of patients receiving CAZ-AVI was 60.5% (n=23), and the mortality rate attributed to 14-day infection was 52.17%. Side effects developed in 18.4% of the patients. None of the developed side effects were such as to require discontinuation of treatment. There was no statistical difference in clinical response and microbiological response in patients receiving combination therapy and monotherapy. Mortality was significantly lower in patients receiving CAZ-AVI monotherapy (p<0.05). Conclusion: We attribute our low clinical success to the late initiation of treatment due to drug reimbursement criteria. Therefore, we think that CAZ-AVI treatment should be started empirically and as soon as possible. We think that our study is valuable in terms of showing that CAZ-AVI treatment should be given in empirical treatment.
目的:头孢他啶/阿维巴坦治疗耐多药肺炎克雷伯菌的实际经验仍然有限。本回顾性研究旨在评价头孢他啶/阿维巴坦治疗碳青霉烯耐药病原菌感染的危重患者的疗效。方法:回顾性分析2022年1月1日至2022年12月31日期间在我院icu住院3天以上、仅头孢他啶/阿维巴坦敏感性增长并开始头孢他啶/阿维巴坦治疗的患者。38名年龄大于18岁的患者被纳入研究。结果:肺炎是ICU最常见的住院原因,脑血管事件次之,内科疾病次之。从采集培养样品到获得实验室结果的平均时间为4.6±1.46天。培养结果经实验室确认后,患者就诊于感染性疾病专科医师至开始治疗的平均时间为1.7±1.3天。患者接受CAZ-AVI单药治疗(57.9%)或联合治疗(42.1%)的平均时间为10.6±4.63天。52.6%的患者获得临床反应,63.2%的患者获得微生物反应。CAZ-AVI患者90天全因死亡率为60.5% (n=23), 14天感染死亡率为52.17%。18.4%的患者出现了副作用。未出现任何需要停止治疗的副作用。联合治疗和单药治疗患者的临床反应和微生物反应无统计学差异。接受CAZ-AVI单药治疗的患者死亡率显著降低(p<0.05)。结论:我们将低临床成功率归因于药物报销标准导致的治疗开始较晚。因此,我们认为应尽快开始经验性治疗CAZ-AVI。我们认为我们的研究在表明CAZ-AVI治疗应该在经验治疗方面是有价值的。
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引用次数: 0
Antibiotic susceptibility of staphylococcus aureus strains isolated from various clinical specimens in a tertiary hospital 某三级医院不同临床标本分离金黄色葡萄球菌菌株的药敏分析
Pub Date : 2023-06-26 DOI: 10.51271/kmj-0098
Ali Öztürk, Nurnehir Baltacı Bozkurt, Tuğba Avan Mutlu
Aims: Staphylococcus aureus infection rates, which are the cause of infections, have rapidly risen in both hospitals and society, constituting a concern. In this study, it was aimed to examine the antibiotic susceptibility of S. aureus strains isolated from patients treated in a tertiary state hospital for four years.Methods: A retrospective analysis was performed on S. aureus strains (n=584) identified from clinical samples delivered to the medical microbiology laboratory of Niğde Ömer Halisdemir University Training and Research Hospital for bacterial culture between 2016 and 2019. The isolates were identified by standard laboratory procedure. VITEK 2 automated system (bioMerieux, France) was used to identification and antibiotic susceptibilities of evaluate the strains.Results: Strains were most commonly isolated from wound swab (n=173) and blood culture (n=107). While the highest resistance rate was observed against Erythromycin (n=232), the least amikacin (n=16) resistant strain was determined. Vancomycin and teicoplanin resistance was not observed.Conclusion: Multi-drug resistance and MRSA resistance still exist today. The absence of vancomycin and teicoplanin resistance, in addition to the low level of trimethoprim-sulfamethoxazole resistance, is encouraging. This information about S. aureus's susceptibility may be helpful in determining how to administer antibiotics.
目的:金黄色葡萄球菌的感染率是引起感染的原因,在医院和社会中都迅速上升,令人担忧。在这项研究中,目的是检查从三级国立医院治疗四年的患者分离的金黄色葡萄球菌菌株的抗生素敏感性。方法:回顾性分析2016 - 2019年送到Niğde Ömer Halisdemir大学培训与研究医院医学微生物实验室进行细菌培养的临床样品中鉴定出的金黄色葡萄球菌菌株(n=584株)。采用标准实验室程序对分离株进行鉴定。采用VITEK 2自动化系统(bioMerieux, France)对菌株进行鉴定和药敏评价。结果:伤口拭子(173例)和血培养(107例)中分离到的细菌最多。对红霉素耐药率最高(n=232),对阿米卡星耐药率最低(n=16)。未见万古霉素和替可普兰耐药。结论:目前仍存在耐多药和MRSA耐药。除了甲氧苄啶-磺胺甲恶唑的低水平耐药性外,没有万古霉素和替柯planin耐药性,这是令人鼓舞的。这些关于金黄色葡萄球菌敏感性的信息可能有助于决定如何使用抗生素。
{"title":"Antibiotic susceptibility of staphylococcus aureus strains isolated from various clinical specimens in a tertiary hospital","authors":"Ali Öztürk, Nurnehir Baltacı Bozkurt, Tuğba Avan Mutlu","doi":"10.51271/kmj-0098","DOIUrl":"https://doi.org/10.51271/kmj-0098","url":null,"abstract":"Aims: Staphylococcus aureus infection rates, which are the cause of infections, have rapidly risen in both hospitals and society, constituting a concern. In this study, it was aimed to examine the antibiotic susceptibility of S. aureus strains isolated from patients treated in a tertiary state hospital for four years.\u0000Methods: A retrospective analysis was performed on S. aureus strains (n=584) identified from clinical samples delivered to the medical microbiology laboratory of Niğde Ömer Halisdemir University Training and Research Hospital for bacterial culture between 2016 and 2019. The isolates were identified by standard laboratory procedure. VITEK 2 automated system (bioMerieux, France) was used to identification and antibiotic susceptibilities of evaluate the strains.\u0000Results: Strains were most commonly isolated from wound swab (n=173) and blood culture (n=107). While the highest resistance rate was observed against Erythromycin (n=232), the least amikacin (n=16) resistant strain was determined. Vancomycin and teicoplanin resistance was not observed.\u0000Conclusion: Multi-drug resistance and MRSA resistance still exist today. The absence of vancomycin and teicoplanin resistance, in addition to the low level of trimethoprim-sulfamethoxazole resistance, is encouraging. This information about S. aureus's susceptibility may be helpful in determining how to administer antibiotics.","PeriodicalId":369732,"journal":{"name":"Kastamonu Medical Journal","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125871130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Kastamonu Medical Journal
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