The diagnosis of sarcoidosis is challenging, especially if the patient has concomitant infectious symptoms. Furthermore, the overlap of immune-mediated and infectious pathologies is not uncommon.
Objective
To report a rare case of association between tuberculosis and sarcoidosis.
Materials and methods
Description of the clinical characteristics of a patient who presented with sarcoidosis superimposed on tuberculosis.
Results
The case of a 29-year-old man with ocular, cutaneous, and systemic symptoms is described. Uveitis and chronic non-caseating granulomatous findings were diagnosed in the skin, lungs, and lymph nodes. Suspicion of tuberculosis led to positive molecular biology tests only in the lymph node biopsy. An overlap of sarcoidosis and tuberculosis was determined, and combined treatment with glucocorticoids and anti-tuberculosis agents was initiated, resulting in improvement of the patient.
Conclusions
Sarcoidosis and tuberculosis share characteristics from their aetiology to clinical manifestations, posing a challenge in clinical differentiation. Cases have been documented where both diseases overlap in the same patient.
{"title":"Convergencia clínica: un caso excepcional de sarcoidosis y tuberculosis con múltiples manifestaciones orgánicas. Reporte de caso","authors":"Néstor Correa-González , María Claudia Díaz , Keyla Jemihah Triana Ángel , María Daniela Polania , Natalia Remolina Murillo , Pilar Alarcón Robles","doi":"10.1016/j.rcreu.2024.01.004","DOIUrl":"10.1016/j.rcreu.2024.01.004","url":null,"abstract":"<div><h3>Introduction</h3><div>The diagnosis of sarcoidosis is challenging, especially if the patient has concomitant infectious symptoms. Furthermore, the overlap of immune-mediated and infectious pathologies is not uncommon.</div></div><div><h3>Objective</h3><div>To report a rare case of association between tuberculosis and sarcoidosis.</div></div><div><h3>Materials and methods</h3><div>Description of the clinical characteristics of a patient who presented with sarcoidosis superimposed on tuberculosis.</div></div><div><h3>Results</h3><div>The case of a 29-year-old man with ocular, cutaneous, and systemic symptoms is described. Uveitis and chronic non-caseating granulomatous findings were diagnosed in the skin, lungs, and lymph nodes. Suspicion of tuberculosis led to positive molecular biology tests only in the lymph node biopsy. An overlap of sarcoidosis and tuberculosis was determined, and combined treatment with glucocorticoids and anti-tuberculosis agents was initiated, resulting in improvement of the patient.</div></div><div><h3>Conclusions</h3><div>Sarcoidosis and tuberculosis share characteristics from their aetiology to clinical manifestations, posing a challenge in clinical differentiation. Cases have been documented where both diseases overlap in the same patient.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"32 1","pages":"Pages 95-102"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140399070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.1016/j.rcreu.2024.01.007
Elías Gonzalo Forero Illera , Andrés Ricardo Fernández Aldana , Daniel Gerardo Fernández Ávila , Edwin Antonio Jáuregui Cuartas , Gloria Vásquez , Monique Chalem , Wilson Bautista Molano
{"title":"Consenso para la gestión de riesgo en la prescripción de terapias biológicas o de antirreumáticos sintéticos con blanco dirigido: Asociación Colombiana de Reumatología 2023","authors":"Elías Gonzalo Forero Illera , Andrés Ricardo Fernández Aldana , Daniel Gerardo Fernández Ávila , Edwin Antonio Jáuregui Cuartas , Gloria Vásquez , Monique Chalem , Wilson Bautista Molano","doi":"10.1016/j.rcreu.2024.01.007","DOIUrl":"10.1016/j.rcreu.2024.01.007","url":null,"abstract":"","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"32 1","pages":"Pages 56-68"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143133938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.1016/j.rcreu.2024.11.001
Jorge Alberto Cortés
{"title":"Riesgo de tuberculosis en pacientes con inmunosupresión: en búsqueda de una vieja conocida","authors":"Jorge Alberto Cortés","doi":"10.1016/j.rcreu.2024.11.001","DOIUrl":"10.1016/j.rcreu.2024.11.001","url":null,"abstract":"","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"32 1","pages":"Pages 1-2"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143133946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}