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Psyche, soul and body: A scoping review on the Greek knowledge about the mental disorders in ancient imperial Rome 心灵、灵魂与身体:古希腊罗马帝国精神疾病知识的概览
Q3 Medicine Pub Date : 2025-01-01 DOI: 10.1016/j.jemep.2025.101082
L. Bottalico , L. Santacroce , S. Topi , I.A. Charitos
The sacred paleo medicine with superstitions and religious ceremonies, applied by shamans and magicians, not only in its organization but also in its therapeutic approach and its interpretative method was the first step for the therapy of mental illnesses. It was part of a mythological system, and its representatives were doctor-priests, who, slowly at the same time, collected clinical and semantic data, paving the way before Hippocrates. To investigate the evolution of such thoughts we extracted data from electronic data banks and ancient books from both public libraries and private collections. The texts of ancient medicine cover an extended period ranging from the “Iππoκρατικό Σώμα” (Corpus Hippocraticum) of the classical period (V-IV century BC) up to the authors of the late classical ages Roman Empire such as e.g., Aretaeus, Celsus, Galen, and others. This work aims to take a journey through the legacy of ancient Greek philosophy concerning the psyche that influenced medicine in Roman Classical age in its diagnosis and therapy for the mentally ill, thus laying the scientific foundations of modern neuropsychiatry.
迷信和宗教仪式的神圣古医学,由萨满和魔术师应用,不仅在其组织上,而且在其治疗方法和解释方法上,是治疗精神疾病的第一步。它是一个神话系统的一部分,它的代表是医生牧师,他们慢慢地收集临床和语义数据,为希波克拉底之前铺平了道路。为了研究这种思想的演变,我们从公共图书馆和私人收藏的电子数据库和古籍中提取了数据。古代医学的文本涵盖了一个很长的时期,从古典时期(公元前v - 4世纪)的“Iππoκρατικό Σώμα”(Corpus hippo克拉底文集)到古典时代晚期罗马帝国的作者,如阿雷泰乌斯、塞尔苏斯、盖伦等人。这项工作旨在通过古希腊哲学的精神遗产进行一次旅行,古希腊哲学对罗马古典时代的精神疾病的诊断和治疗产生了影响,从而奠定了现代神经精神病学的科学基础。
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引用次数: 0
Blockchain and homomorphic encryption for genomic and health data sharing: An ethical perspective 基因组和健康数据共享的区块链和同态加密:伦理观点
Q3 Medicine Pub Date : 2025-01-01 DOI: 10.1016/j.jemep.2025.101127
S.A. Ahmed , R. Hrzic

Background

Sharing genomic data is crucial for public health research, yet it poses significant privacy risks, necessitating innovative solutions to balance data accessibility with individual protection. This study investigates the ethical dimensions of a hybrid system integrating blockchain and homomorphic encryption for secure genomic data sharing in health contexts.

Methods

We conducted a literature review of studies in MEDLINE and Google Scholar, and used the eight peer-reviewed studies uncovered to construct an in-depth description of the hybrid system. We then assessed its performance in achieving public ethics objectives using a framework derived from published public health ethics principles pertaining to data sharing in public health. The evaluation involved conducting a thematic analysis of the information relevant to each objective from the published studies.

Results

We find that the hybrid system aligns well with tenets of public health ethics, including accountability, fairness, respect for persons, privacy, and public health goals, through mechanisms like transparent record-keeping, secure data access, and privacy-preserving computation. However, scalability poses a major challenge, hindered by computational overhead and insufficient stakeholder comprehension.

Conclusions

Our results imply that while the hybrid system can support data sharing while safeguarding individual rights, its practical implementation is limited without addressing scalability. This study underscores the need to highlight scalability as a fundamental ethical principle in evaluating digital public health technologies.
共享基因组数据对公共卫生研究至关重要,但它带来了重大的隐私风险,需要创新的解决方案来平衡数据可访问性和个人保护。本研究探讨了整合区块链和同态加密的混合系统在健康环境下安全基因组数据共享的伦理维度。方法对MEDLINE和谷歌Scholar上的相关研究进行文献综述,并利用已发现的8篇同行评议研究对该混合系统进行深入描述。然后,我们使用与公共卫生数据共享相关的已发表的公共卫生伦理原则衍生的框架来评估其在实现公共卫生伦理目标方面的表现。评价涉及对已发表的研究报告中与每个目标有关的资料进行专题分析。结果我们发现,混合系统通过透明的记录保存、安全的数据访问和隐私保护计算等机制,很好地符合公共卫生伦理原则,包括问责制、公平、尊重个人、隐私和公共卫生目标。然而,可伸缩性带来了重大挑战,受到计算开销和涉众理解不足的阻碍。结论混合系统虽然可以在保障个人权利的同时支持数据共享,但其实际实施受到限制,没有解决可扩展性问题。这项研究强调,在评估数字公共卫生技术时,需要强调可扩展性是一项基本的伦理原则。
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引用次数: 0
Book review: “Rethinking Conscientious Objection in Health Care” by Alberto Giubilini, Udo Schuklenk, Francesca Minerva, and Julian Savulescu 书评:阿尔贝托·朱比利尼、乌多·舒克伦克、弗朗西斯卡·密涅瓦和朱利安·萨乌列斯库著的《重新思考医疗保健中的良心反对》
Q3 Medicine Pub Date : 2025-01-01 DOI: 10.1016/j.jemep.2025.101155
E.M. Torres
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引用次数: 0
End of life and death – dead body in Québec law 生与死的终结——尸体在死亡法中
Q3 Medicine Pub Date : 2025-01-01 DOI: 10.1016/j.jemep.2025.101135
M. Lacroix
The author will first deal with the moment of death, before discussing the status of human remains in Québec private law.
撰文人将首先讨论死亡的时刻,然后再讨论人类遗骸在瞿氏私法中的地位。
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引用次数: 0
Dispositional moral attribution and association avoidance: Explaining chronic Mpox stigma even after recovery 性格道德归因和联想回避:解释慢性m痘病耻感即使在康复后
Q3 Medicine Pub Date : 2025-01-01 DOI: 10.1016/j.jemep.2025.101151
S. Davoudpour , R.O. Salvador , M.G. Curtis , A.L. French , S.G. Hosek , G. Phillips II , P.A. Serrano

Background

Prior research indicates that disease-related stigma (e.g., mpox stigma) tends to perpetuate even after the conclusion of the infection. For instance, HIV stigma remains highly prevalent despite the proliferation of stigma-reducing public health initiatives and campaigns. Perpetuation of these stigmas, especially association avoidance well after recovery, has somewhat confounded scholars and public health officials alike. In this study, using the concept of dispositional moral attribution, we offer an explanation for this perpetuated stigma.

Methodology

We developed multiple logistic regression models using data from the mpox substudy of the Keeping it LITE study. This cross-sectional survey was conducted in Illinois, USA in September 2022 and collected the attitudes of 226 sexual minority individuals towards the 2022 mpox outbreak in Illinois.

Results/discussion

Findings indicate a significant positive relationship between moral attribution and association avoidance of those who have recovered from mpox. Individuals who believe those with mpox have participated in immoral activities are 4.5 times as likely to avoid association with those who recovered from mpox compared to those who do not associate mpox with immoral activities.

Conclusion

We conclude that chronic stigmatization, in the form of association avoidance, is more likely when the stigmatized status of an individual is presumed to be the result of their own immoral behavior. Destigmatization campaigns are encouraged to take this finding into account when framing their efforts.
先前的研究表明,与疾病相关的柱头(例如m痘柱头)甚至在感染结束后也会持续存在。例如,尽管减少污名的公共卫生倡议和运动激增,但对艾滋病毒的污名仍然非常普遍。这些耻辱的延续,尤其是在康复后很长一段时间内避免联想,在某种程度上让学者和公共卫生官员都感到困惑。在这项研究中,我们使用性格道德归因的概念,为这种长期存在的耻辱提供了一个解释。方法采用keep it LITE研究的mpox子研究数据建立了多个逻辑回归模型。本横断面调查于2022年9月在美国伊利诺伊州进行,收集226名性少数群体对2022年伊利诺伊州麻疹疫情的态度。结果/讨论研究结果表明,mpox恢复者的道德归因与联想回避之间存在显著的正相关。认为患有m痘的人参与过不道德活动的人避免与那些从m痘中康复的人交往的可能性是那些没有将m痘与不道德活动联系起来的人的4.5倍。我们的结论是,当一个人的污名化状态被认为是他们自己不道德行为的结果时,以联想回避的形式出现的慢性污名化更有可能发生。鼓励去污名化运动在制定其努力时考虑到这一发现。
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引用次数: 0
How vaccine-derived poliovirus has questioned the public health response to emerging infectious diseases 疫苗衍生脊髓灰质炎病毒如何质疑公共卫生对新发传染病的反应
Q3 Medicine Pub Date : 2025-01-01 DOI: 10.1016/j.jemep.2025.101152
A. Zarzeczny, P. Kahar, V. Weiss

Background

This review aims to explore the existence of poliovirus from the peak of epidemics to modern resurgences, understand its public health response in polio-endemic countries, and the influence of public perceptions of vaccine-derived polio on its eradication progress.

Methodology

A literature search was conducted using combinations of the search terms polio, eradication, vaccine-derived, global, resurgence, Covid-19, and vaccination. A total of 15 articles were included in the review.

Discussion

Polio has become overshadowed by recent health issues dominating the interest of public health agencies and the World Health Organization. Endemic countries struggle to eradicate polio as civil conflict, foreign distrust, and public health misinformation have produced a lack of political will to eradicate polio. Furthermore, the militarization of public health has caused eradication initiatives to lose their credibility and has painted humanitarian aid as an ulterior motive. Additionally, countries that are struggling to contain polio are suffering from resource shortages and new health issues prompted by the Covid-19 pandemic. As millions of immunizations were missed during the pandemic, there has been concern for a global uprising of polio following surges of polio cases in both endemic and polio-free countries. Although eradication programs in the past have emphasized the need for programs tailored to communities’ needs and a strong sense of global collaboration, this strategy has been poorly utilized by recent polio programs.

Conclusion

Efforts to eliminate polio go beyond acquiring the tools for eradication. Although effective interventions and screening procedures for polio exist, eradication cannot be achieved unless barriers to accessibility and poor political will are addressed. Given this, polio resurgences demand a change in the way polio is perceived by the public as well as a unified global commitment to eradicate polio.
本综述旨在探讨脊髓灰质炎病毒从流行高峰到现代死灰复燃的存在,了解脊髓灰质炎流行国家的公共卫生应对措施,以及公众对疫苗衍生脊髓灰质炎的认知对其根除进展的影响。方法结合脊髓灰质炎、根除、疫苗衍生、全球、死灰复燃、Covid-19和疫苗接种等搜索词进行文献检索。本综述共纳入15篇文章。最近,公共卫生机构和世界卫生组织关注的卫生问题给脊髓灰质炎蒙上了阴影。由于国内冲突、外国的不信任和公共卫生方面的错误信息,流行国家难以根除脊髓灰质炎,导致缺乏根除脊髓灰质炎的政治意愿。此外,公共卫生的军事化使根除倡议失去了信誉,并把人道主义援助描绘成别有用心的动机。此外,正在努力控制脊髓灰质炎的国家正遭受资源短缺和Covid-19大流行引发的新卫生问题的困扰。由于在大流行期间错过了数百万人的免疫接种,在流行和无脊髓灰质炎国家出现脊髓灰质炎病例激增之后,人们一直担心全球脊髓灰质炎会爆发。尽管过去的根除计划强调需要根据社区的需要和强烈的全球合作意识制定计划,但这一战略在最近的脊髓灰质炎计划中没有得到充分利用。结论消除脊髓灰质炎的努力不仅仅是获得根除工具。尽管存在有效的脊髓灰质炎干预措施和筛查程序,但除非解决无障碍障碍和政治意愿不佳的问题,否则无法实现根除。鉴于此,脊髓灰质炎的死灰复燃要求改变公众对脊髓灰质炎的看法,并要求全球对根除脊髓灰质炎作出统一承诺。
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引用次数: 0
Overcoming language barriers in pediatric clinical research: A qualitative study of researchers' views 克服儿科临床研究中的语言障碍:对研究者观点的定性研究
Q3 Medicine Pub Date : 2025-01-01 DOI: 10.1016/j.jemep.2025.101171
S. Chhina , S. Moreheart , J. Claydon , B. Udall , M. Sadarangani , H. Longstaff , A. Orth , Q. Doan

Background

Limited English proficiency (LEP) can act as a barrier to equitable access to pediatric clinical research participation. This study examined researchers' perspectives on challenges and opportunities for including patients and families with LEP.

Methods

Semi-structured interviews were conducted with 26 researchers and hospital leaders at two hospitals in British Columbia, Canada. Interviews explored experiences offering research opportunities to populations with LEP and perceived barriers and facilitators. Thematic analysis was used to analyze interview transcripts.

Results

Five themes emerged: 1) lack of translation/interpretation resources; 2) unclear best practices; 3) doubts about translation quality; 4) low prioritization; 5) facilitators. Barriers existed at institutional and individual levels.

Conclusion

A comprehensive approach is needed to support equitable participation of patients with LEP in pediatric health research, including increased funding, cultural competence training, community partnerships, and language-inclusive design. Recognizing and addressing multi-level barriers can promote fully representative and equitable research participation for populations with LEP.
背景有限的英语水平(LEP)可能成为公平获得儿科临床研究参与的障碍。本研究考察了研究人员对包括LEP患者和家庭在内的挑战和机遇的看法。方法对加拿大不列颠哥伦比亚省两所医院的26名研究人员和医院领导进行半结构化访谈。访谈探讨了为LEP人群提供研究机会的经验,以及感知到的障碍和促进因素。访谈笔录采用专题分析。结果:1)翻译资源不足;2)最佳实践不明确;3)对翻译质量的质疑;4)优先级低;5)主持人。体制和个人两级都存在障碍。结论需要采取综合措施支持LEP患者公平参与儿科健康研究,包括增加资金、文化能力培训、社区合作和语言包容性设计。认识和解决多层次障碍可以促进LEP人群充分代表性和公平的研究参与。
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引用次数: 0
Bridging worlds: A case-series on cultural challenges for second-generation oncological adolescents with palliative care needs 弥合世界:第二代肿瘤青少年与姑息治疗需求的文化挑战的案例系列
Q3 Medicine Pub Date : 2025-01-01 DOI: 10.1016/j.jemep.2025.101177
A. Santini , A. Mercante , A. Marinetto , F. Benini
The role of the child and family’s cultural dimension in influencing healthcare experiences and outcomes has been increasingly recognized in pediatric palliative care (PPC). Therefore, a culturally sensitive project of care is essential to allow the person-centered, holistic, and tailored approach that characterizes PPC. However, this is not always easy.
Second-generation immigrants have a unique social and cultural background and may face numerous challenges in balancing their bicultural identity. This report explores the complexities associated with shared decision-making and individual care planning within the realm of PPC across diverse cultural contexts. It employs an illustrative case series to emphasize the need to build bridges between different cultures within which the young person lives and finds balance.
Serving as intermediaries for their families, they often endure uncomfortable and demanding roles, which results in a diminished awareness of their personal needs and concerns. Clinicians generally find it more effective to engage directly with the adolescent rather than with their parents, often presuming that the parents share values and beliefs similar to those of their child. However, such assumptions may overlook significant cultural and generational disparities.
Delivering comprehensive support to adolescents within these dynamics is imperative, as it assists them in managing their intricate roles and navigating cultural disparities. Concurrently, enhancing clinicians’ awareness of these dynamics is vital for promoting a more culturally competent approach to care. This discourse emphazises strategies for effective communication and bridging cultural differences, outlining implications for practice and policy in multicultural environments.
在儿童姑息治疗(PPC)中,儿童和家庭的文化维度在影响医疗保健经验和结果方面的作用日益得到认可。因此,一个具有文化敏感性的护理项目对于以人为本、整体和量身定制的PPC方法至关重要。然而,这并不总是那么容易。第二代移民具有独特的社会和文化背景,在平衡他们的双文化身份方面可能面临许多挑战。本报告探讨了在不同文化背景下PPC领域内与共同决策和个人护理计划相关的复杂性。它采用了一个说明性的案例系列来强调需要在不同的文化之间建立桥梁,年轻人在其中生活并找到平衡。作为家庭的中间人,她们经常忍受着不舒服和苛刻的角色,这导致她们对个人需求和关切的认识减少。临床医生通常发现,直接与青少年接触比与他们的父母接触更有效,他们通常假设父母与他们的孩子有着相似的价值观和信仰。然而,这种假设可能忽略了重要的文化和代际差异。在这些动态中向青少年提供全面支持是必不可少的,因为这有助于他们管理自己复杂的角色和应对文化差异。同时,提高临床医生对这些动态的认识对于促进更具文化竞争力的护理方法至关重要。本文强调有效沟通和弥合文化差异的策略,概述了在多元文化环境中实践和政策的含义。
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引用次数: 0
The ethics of exposure: Relational bioethics, responsibility, and systemic failure in psychiatry and mental healthcare 暴露的伦理:精神病学和精神保健中的关系生物伦理、责任和系统失败
Q3 Medicine Pub Date : 2025-01-01 DOI: 10.1016/j.jemep.2025.101189
P. Scognamiglio , D. Morena

Background

This study examines the ethical, institutional, and legal factors influencing psychiatric care in Italy, highlighting how systemic fragmentation, chronic underfunding, and increasing medico-legal liability contribute to moral distress among clinicians and the adoption of defensive psychiatric practices. The objective is to assess the impact of these factors on both patient outcomes and the capacity of healthcare professionals to deliver effective and ethically sound care.

Methodology

Using a qualitative, narrative-based, and reflexive methodology, the paper draws on the testimonies of the authors and a series of anonymized clinical narratives, including but not limited to cases of suicide. These accounts were selected for their paradigmatic value in revealing structural dynamics, rather than for statistical representativeness. The analysis combines narrative ethics and relational bioethics to examine how systemic vulnerability manifests in everyday psychiatric practice.

Discussion

Fear of litigation and institutional abandonment can significantly influence clinical judgment, resulting in excessive control measures, procedural overreach, and emotional exhaustion among healthcare professionals. Defensive practices – such as over-hospitalization, over-prescription, and hyper-documentation – arise not from negligence but as adaptive responses to institutional fragility.

Perspectives

The study offers three key contributions. First, it recalls the One Health paradigm as the only viable framework for bringing together mental healthcare and institutional ethics, highlighting the need for interdependent and ethically sustainable systems of care. Second, it situates the Italian case within a broader reflection on the erosion of meaning in mental health practice within systems that demand total accountability without offering protection to their professionals. Finally, it calls for institutional architectures capable of sustaining both clinical presence and shared responsibility.
本研究考察了影响意大利精神科护理的伦理、制度和法律因素,强调了系统碎片化、长期资金不足和不断增加的医疗法律责任如何导致临床医生的道德困境和采用防御性精神科实践。目的是评估这些因素对患者结果和医疗保健专业人员提供有效和合乎道德的护理的能力的影响。方法:采用定性的、基于叙述的和反思性的方法,本文借鉴了作者的证词和一系列匿名的临床叙述,包括但不限于自杀病例。选择这些账户是因为它们在揭示结构动态方面的范例价值,而不是统计代表性。该分析结合了叙事伦理学和关系生命伦理学来研究系统脆弱性如何在日常精神病学实践中表现出来。对诉讼和机构遗弃的恐惧会显著影响临床判断,导致医疗保健专业人员控制措施过度、程序过度和情绪耗竭。防御性做法——如过度住院、过度处方和过度记录——并非源于疏忽,而是对制度脆弱性的适应性反应。该研究提供了三个关键贡献。首先,它回顾了“同一个健康”范式,认为这是将精神卫生保健和机构伦理结合在一起的唯一可行框架,强调需要建立相互依存和道德上可持续的护理系统。其次,它将意大利的案例置于一个更广泛的反思中,即在要求完全问责而不为其专业人员提供保护的系统中,精神卫生实践的意义受到侵蚀。最后,它需要能够维持临床存在和共同责任的机构架构。
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引用次数: 0
Care and support for the elderly in France: Major managerial challenges 对法国老年人的照顾和支持:主要的管理挑战
Q3 Medicine Pub Date : 2025-01-01 DOI: 10.1016/j.jemep.2025.101161
C. Pascal

Background

France, like many other developed countries, is experiencing a significant demographic transition marked by an ageing population. This shift has resulted in a growing demand for care and support services for older people. In response, the French government has implemented several policy measures, including the promotion of home-based care and the development of coordination support systems, in an effort to maintain autonomy and contain costs.

Objectives

This article aims to identify and analyze the main managerial challenges that elderly care institutions and services in France must address to adapt to the changing healthcare and social landscape.

Methods

The analysis is based on a selective review of recent French official reports and peer-reviewed scientific publications related to elderly care policies, service organization, and workforce management.

Findings

Five major managerial challenges are identified:
- Strategic human resources management – The sector faces severe workforce shortages, particularly among nurses and care workers, due to low pay, difficult working conditions, and limited career prospects.
- Operations management and planning – Rising costs associated with increasing care needs, real estate expenses, and regulatory requirements necessitate enhanced efficiency and procurement strategies.
- Organizational memory – High staff turnover risks eroding institutional know-how and calls for procedural reinforcement to sustain quality and safety in care delivery.
- Care pathways – While public authorities seek greater coordination and integration of health and social services, operationalising this ambition remains difficult due to institutional fragmentation, ambiguous responsibilities, and a lack of shared tools and data.
- Transportation and mobility – The limited mobility of frail older adults complicates their access to healthcare and support services. This challenge is exacerbated by rising energy costs and environmental policies aimed at reducing car travel, which constrain traditional models of transportation. While e-health solutions offer promising alternatives to in-person care, their deployment requires a broader reconfiguration of service delivery models and associated economic structures.

Conclusion

Elderly care services in France must navigate multiple structural and operational challenges to adapt to demographic and systemic changes. Addressing these issues requires strategic investment in workforce development, service coordination, and innovation in care delivery mechanisms.
与许多其他发达国家一样,法国正在经历以人口老龄化为标志的重大人口转型。这一转变导致对老年人护理和支助服务的需求日益增长。作为回应,法国政府实施了若干政策措施,包括促进家庭护理和发展协调支持系统,以保持自主权和控制成本。本文旨在确定和分析法国老年护理机构和服务必须解决的主要管理挑战,以适应不断变化的医疗保健和社会景观。方法分析是基于最近法国官方报告和同行评议的科学出版物的选择性审查,涉及老年护理政策,服务组织和劳动力管理。战略人力资源管理-由于低工资、艰苦的工作条件和有限的职业前景,该行业面临严重的劳动力短缺,特别是护士和护理工作者。-运营管理和规划-随着护理需求、房地产费用和监管要求的增加,成本不断上升,需要提高效率和采购策略。-组织记忆-高人员流动率有侵蚀机构知识的风险,需要加强程序,以维持护理服务的质量和安全。-护理途径-虽然公共当局寻求加强卫生和社会服务的协调和整合,但由于机构分散、责任模糊以及缺乏共享的工具和数据,实现这一目标仍然很困难。-交通和流动性-体弱老年人的流动性有限,使他们难以获得保健和支助服务。不断上涨的能源成本和旨在减少汽车出行的环境政策加剧了这一挑战,而汽车出行限制了传统的交通方式。虽然电子保健解决方案为面对面护理提供了有希望的替代方案,但它们的部署需要更广泛地重新配置服务提供模式和相关的经济结构。结论法国的老年护理服务必须应对多种结构和运营挑战,以适应人口和体制的变化。解决这些问题需要在劳动力发展、服务协调和护理提供机制创新方面进行战略投资。
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引用次数: 0
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Ethics, Medicine and Public Health
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