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The Impact of Patient Characteristics on Total Hospital Cost in Patients Undergoing Coronary Artery Bypass Grafting 患者特征对冠状动脉搭桥术患者住院总费用的影响
Q3 Medicine Pub Date : 2025-01-01 DOI: 10.1016/j.jemep.2025.101072
J. Katsiroubas , J. Wong , K. Jonnalagadda , T.S. Guy

Introduction

Coronary artery bypass graft (CABG) is one of the most common surgeries in the United States, with an average cost around $40,000. However, the burden of these costs may fall unequally among patients of different demographic groups. The objective of this study is to characterize factors associated with increased total cost after coronary artery bypass graft surgery.

Methods

The Statewide Planning and Research Cooperative System (SPARCS) database for years 2017–2021 was queried to identify patients who had undergone CABG in New York State. Patient characteristics including gender, age, race, and All Patient Refined (APR) severity of illness (SOI), and risk of mortality (ROM) were analyzed. The Primary outcome was total cost. Data was analyzed using Student t-test and univariate analysis.

Results

Between 2017 and 2021, 38,344 patients, 76.6% male, underwent CABG in New York State. Race was documented identifying 67.0% White, 7.0% Black/African American, 0.7% multiracial, and 25.4% other. The mean length of stay (LOS) was 9.9 days. The average total hospital cost was $61,596.90. The average hospital cost for Black/African Americans was $71,683.12, 19.7% ($14,119.67) more than Whites, the lowest paying racial group (13.56 P < 0.05). Black/African Americans also had the longest average LOS of 11.7 days, compared to 9.6 days for white patients, 11.3 days for multi-racial patients and 10.3 days for those who identified as other. Univariate analysis exhibited factors associated with the top quartile of hospital cost (≥$68,608) for CABG included Black/ African American race (2.01 CI 0.61−0.78), LOS more than 6 days (9.68, CI 2.18–2.35), major APR severity of illness (5.55, CI 1.15–1.91) and extreme (28.09, CI 3.13–3.54) and major (5.28, CI 1.56–1.76) and extreme APR risk of mortality (16.9, CI 2.72–2.94).

Conclusion

The cost of coronary artery bypass grafting surgery is influenced by a variety of factors including race, APR severity score, mortality risk and length of stay.
冠状动脉旁路移植术(CABG)是美国最常见的手术之一,平均费用约为4万美元。然而,这些费用的负担在不同人口群体的患者中可能不平等。本研究的目的是表征冠状动脉搭桥手术后总成本增加的相关因素。方法查询2017-2021年全州规划与研究合作系统(SPARCS)数据库,以确定纽约州接受CABG的患者。分析患者特征,包括性别、年龄、种族、所有患者精炼(APR)疾病严重程度(SOI)和死亡风险(ROM)。主要结果是总成本。数据分析采用学生t检验和单变量分析。结果2017年至2021年期间,纽约州有38,344例患者(76.6%为男性)接受了CABG。种族被记录为67.0%白人,7.0%黑人/非裔美国人,0.7%多种族,25.4%其他。平均住院时间(LOS)为9.9天。平均总住院费用为61 596.90美元。黑人/非裔美国人的平均住院费用为71,683.12美元,比白人(13.56 P <;0.05)。黑人/非裔美国人的平均死亡时间最长,为11.7天,而白人患者为9.6天,多种族患者为11.3天,其他种族患者为10.3天。单因素分析显示,与CABG住院费用(≥68,608美元)最高四分位数相关的因素包括黑人/非裔美国人种族(2.01 CI 0.61−0.78)、LOS超过6天(9.68,CI 2.18—2.35)、APR严重程度(5.55,CI 1.15—1.91)和APR严重死亡风险(28.09,CI 3.13—3.54)和APR严重死亡风险(5.28,CI 1.56—1.76)(16.9,CI 2.72—2.94)。结论冠状动脉搭桥术费用受种族、APR严重程度评分、死亡风险和住院时间等多种因素影响。
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引用次数: 0
The US healthcare system facilitates medical conspiracy theories: A call to action 美国医疗体系助长了医疗阴谋论:行动呼吁
Q3 Medicine Pub Date : 2025-01-01 DOI: 10.1016/j.jemep.2025.101090
C. Bobier, J. Obeid
Medical conspiracy theories pose a public health risk and erode trust in healthcare providers. While research continues on the psychological, social, and evolutionary foundations of conspiratorial thinking, as well as on intervention strategies, less attention has been given to the role of healthcare system structures. This paper examines how the design and delivery of the U.S. healthcare system contribute to the spread of medical conspiracy theories. Using a two-pronged analytical framework, we (1) identify key features of the U.S. healthcare system and patient experience and (2) map these features onto known psychological and social drivers of conspiratorial beliefs. We argue that addressing medical conspiracy theories requires not only individual or community-level interventions but also structural reforms in healthcare. Researchers should therefore explore the feasibility and impact of systematic changes in mitigating conspiratorial thinking.
医学阴谋论对公众健康构成威胁,侵蚀了人们对医疗服务提供者的信任。虽然对阴谋思维的心理、社会和进化基础以及干预策略的研究仍在继续,但对医疗保健系统结构的作用的关注较少。本文探讨了美国医疗保健系统的设计和交付如何有助于医疗阴谋论的传播。使用双管齐下的分析框架,我们(1)确定美国医疗保健系统和患者体验的关键特征,(2)将这些特征映射到已知的阴谋论信念的心理和社会驱动因素。我们认为,解决医疗阴谋论不仅需要个人或社区层面的干预,还需要医疗保健的结构性改革。因此,研究者应该探索系统变革在减轻阴谋思想方面的可行性和影响。
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引用次数: 0
Shifting landscapes: Post-COVID-19 infectious disease focus in Vietnam 变化的景观:越南后covid -19传染病的焦点
Q3 Medicine Pub Date : 2025-01-01 DOI: 10.1016/j.jemep.2025.101083
N.X. Ha , A.M. Nguyen , R. Elsheikh , A.M. Makram , N.T. Huy
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引用次数: 0
Emerging infectious threats: first identification of reovirus cases in Bangladesh 新出现的传染性威胁:孟加拉国首次发现呼肠孤病毒病例
Q3 Medicine Pub Date : 2025-01-01 DOI: 10.1016/j.jemep.2025.101050
S. Jamil , S. Biswas , N. Ali , F. Ahmed
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引用次数: 0
Bioethical challenges and artificial intelligence, focus Quebec/France 生物伦理挑战和人工智能,聚焦魁北克/法国
Q3 Medicine Pub Date : 2025-01-01 DOI: 10.1016/j.jemep.2025.101058
O. Gout , M. Lacroix
The authors discuss the potential benefits of AI for the healthcare system. To do this, they consider the importance of ensuring the confidentiality of medical data, maintaining a patient-doctor relationship imbued with humanity, as well as liability remedies specific to stemming the potential abuses of AI.

Context

In the healthcare sector, both in France and in Canada, AI is expected to be a tool for transforming and democratising healthcare by improving its quality, safety and effectiveness. We therefore need to analyse the legal framework in place to ensure that these objectives are met.

Methodology

The question is addressed on the basis of a study of the rules through the diversity of their conception, their implementation by the courts (case law) and their analysis by the authors making up the doctrine.

Results/discussion

The authors discuss the potential benefits of AI for the healthcare system. To do this, they consider the importance of ensuring the confidentiality of medical data, maintaining a patient-doctor relationship imbued with humanity, as well as liability remedies specific to stemming the potential abuses of AI.

Conclusion/outlook

While the regulations applicable to AI are considered to be relevant and appropriate for taking account of the various issues, particularly in terms of privacy and liability, it will be necessary to remain attentive to their implementation in order to ensure that the objectives are effectively achieved.
作者讨论了人工智能对医疗系统的潜在好处。为此,他们考虑了确保医疗数据保密、维持充满人性的医患关系以及为遏制人工智能的潜在滥用而专门制定的责任补救措施的重要性。在法国和加拿大的医疗保健行业,人工智能有望通过提高质量、安全性和有效性,成为医疗保健转型和民主化的工具。因此,我们需要分析现有的法律框架,以确保实现这些目标。方法论:通过对规则概念的多样性、法院(判例法)对规则的实施以及构成原则的作者对规则的分析来研究这些规则,从而解决这个问题。结果/讨论作者讨论了人工智能对医疗系统的潜在好处。为此,他们考虑了确保医疗数据保密、维持充满人性的医患关系以及为遏制人工智能的潜在滥用而专门制定的责任补救措施的重要性。结论/展望虽然适用于人工智能的法规被认为是相关和适当的,以考虑到各种问题,特别是在隐私和责任方面,但仍有必要继续关注其实施情况,以确保有效实现目标。
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引用次数: 0
The impact of United States’ withdrawal from the WHO on global health equity and pandemic preparedness 美国退出世卫组织对全球卫生公平和大流行病防范的影响
Q3 Medicine Pub Date : 2025-01-01 DOI: 10.1016/j.jemep.2025.101057
Y.B. Abdullahi , M.M. Ahmed
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引用次数: 0
The minor’s healthcare 未成年人的医疗保健
Q3 Medicine Pub Date : 2025-01-01 DOI: 10.1016/j.jemep.2025.101089
L. Sauvé
This article explores the regulation of children’s healthcare under French law, taking into consideration the role of parents, the welfare of the child, and the child’s autonomy. Parents primarily make healthcare decisions on behalf of their child’s, acting as representatives of the child’s best interests within the framework of parental authority. The level of consent required depends on the seriousness of the medical decision at hand; for everyday medical matters, one parent’s consent may suffice, while decisions involving the child’s physical well-being may necessitate consent from both parents. Despite the central role of parents, French law underscores that all parental decisions must prioritise the child’s welfare. Consequently, parents cannot make arbitrary decisions, and certain actions are mandatory, even if parents are unwilling to carry them out. Furthermore, in the past four decades, there has been a growing emphasis on children’s rights, prompting the French legislator to increasingly acknowledge children’s voices, especially in healthcare-related matters. Today, the legislator grants various rights to the child, such as the right to veto, the right to consent to decisions alongside their parents, and sometimes the right to act independently without consulting their parents. In sum, French legislation has aimed to strike a balance between recognising the child’s autonomy and the imperative of protecting them from their own decisions.
本文探讨了法国法律对儿童保健的规定,考虑到父母的作用、儿童的福利和儿童的自主权。父母主要代表孩子做出医疗保健决定,在父母权威的框架内代表孩子的最大利益。所要求的同意程度取决于当前医疗决定的严重性;对于日常医疗问题,父母一方的同意可能就足够了,而涉及儿童身体健康的决定可能需要父母双方的同意。尽管父母扮演着核心角色,但法国法律强调,父母的所有决定都必须优先考虑孩子的福利。因此,父母不能武断地做决定,某些行为是强制性的,即使父母不愿意执行它们。此外,在过去四十年中,越来越重视儿童权利,促使法国立法者日益承认儿童的声音,特别是在与保健有关的问题上。今天,立法者授予儿童各种权利,例如否决权,与父母一起同意决定的权利,有时还有不征求父母意见而独立行动的权利。总而言之,法国的立法旨在在承认儿童的自主权和保护他们不受自己决定的必要性之间取得平衡。
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引用次数: 0
Focus philosophy: Transgenderism, conceptual and ethical aspects 关注哲学:跨性别主义,概念和伦理方面
Q3 Medicine Pub Date : 2025-01-01 DOI: 10.1016/j.jemep.2025.101163
P. Le Coz

Context

Usually, a person’s identity is defined in terms of their physical characteristics. A “man” is someone who looks like a man; a “woman” is someone who looks like a woman. Our spontaneous criteria are a person’s physical appearance, silhouette and mannerisms. “Man” is a gender assigned to “males” based on physical features: XY karyotype, increased body hair and muscle mass, deeper voice, testosterone dominance, penis, testicles, sperm, etc. “Woman” is a gender assigned to “females” identifiable by a different set of traits: XX karyotype, breasts, estrogen dominance, vulva, clitoris, vagina, ovaries, etc. These different elements are now being debated and called into question in the case of gender dysphoria.

Methodology

The theme addressed here is analyzed from a philosophical and ethical perspective. Attention is paid both to the form, dealing with the notions of sex, gender, transgenderism or transexualism, and to the substance, by mobilizing philosophical and ethical principles that enable us to reflect on the notion of identity.

Results/discussion

Society posits that gender identity (man, woman) is a matter of biological characteristics (male, female). From a transgender perspective however, a person’s true identity depends on their personal experience. Nobody is better placed to know whether a person is a man or a woman than the person themself, because gender arises from internal bodily experience. Contrary to conventional wisdom, a transgender individual doesn’t necessarily change sex but asserts a different gender from the one assigned to them by society based on biological criteria. Moral dilemmas arise from the moment the transgender person wishes to benefit from a treatment whose effects are dangerous and irreversible. In this case, decisions depend on the therapeutic alliance, physicians being obliged to not perform acts whose efficacy they consider doubtful. Interventions on a healthy body should only be considered if they are based on a firm will and reiterated over long time scale. They can only be covered by health insurance on the basis of a medical indication.

Conclusion/outlook

The issue of transgenderism is increasingly being raised in relation to children, an audience for whom caution is particularly important. Their brain is still developing and their desire may evolve so that they no longer feel out of step with their anatomical characteristics. According to the Hippocratic precept, in medicine it is important above all not to harm.
通常,一个人的身份是根据他们的身体特征来定义的。“男人”是指看起来像男人的人;“女人”是指看起来像女人的人。我们自发的标准是一个人的外表、轮廓和举止。“男人”是根据身体特征分配给“男性”的性别:XY核型,体毛和肌肉量增加,声音低沉,睾酮主导,阴茎,睾丸,精子等。“女人”是分配给“女性”的性别,通过一组不同的特征来识别:XX核型,乳房,雌激素主导,外阴,阴蒂,阴道,卵巢等。这些不同的因素现在正在被讨论,并在性别焦虑的情况下受到质疑。方法学这里讨论的主题是从哲学和伦理的角度分析的。我们既注意形式,处理性、性别、跨性别主义或易性主义的概念,也注意实质,通过调动使我们能够反思身份概念的哲学和伦理原则。结果/讨论社会认为性别认同(男人、女人)是生理特征(男性、女性)的问题。然而,从跨性别者的角度来看,一个人的真实身份取决于他们的个人经历。没有人比这个人自己更能知道一个人是男是女,因为性别来自于内在的身体体验。与传统观念相反,跨性别者并不一定要改变性别,而是主张一种不同于社会根据生理标准赋予他们的性别。当跨性别者希望从一种危险且不可逆转的治疗中获益时,道德困境就出现了。在这种情况下,决定取决于治疗联盟,医生有义务不执行他们认为疗效可疑的行为。对健康身体的干预,只有基于坚定的意志,并在很长一段时间内反复进行,才应予以考虑。他们只有在有医疗指征的情况下才能享受健康保险。结论/展望跨性别主义的问题越来越多地与儿童有关,对儿童群体来说,谨慎尤为重要。他们的大脑仍在发育,他们的欲望可能会进化,这样他们就不会再感到与他们的解剖学特征不一致。根据希波克拉底的格言,在医学上最重要的是不要伤害他人。
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引用次数: 0
How can euthanasia and assisted suicide regulation guarantee patient health and autonomy? Lesson from nine European countries 安乐死和协助自杀法规如何保障病人的健康和自主权?来自9个欧洲国家的教训
Q3 Medicine Pub Date : 2025-01-01 DOI: 10.1016/j.jemep.2025.101131
M. Gulino , M. Martelli , P. Ricci , S. Marinelli , G. Montanari Vergallo

Background

This paper aims to reflect on whether substantive limits should be implemented and what procedural rules should be introduced by legislators wishing to legalize euthanasia or assisted suicide (EAS) to guarantee health and autonomy of both the mentally ill and other patients.

Methodology

We analyzed and compared the rules of the nine European States (the Netherlands, Belgium, Luxembourg, Austria, Portugal, Spain, Italy, Switzerland and Germany) where EAS is lawful.

Discussion

The increase of countries that in the last years have implemented or introduced regulations on EAS leads us to think that: (a) substantive requirements should not be reduced, for example, allowing healthy people to access EAS; (b) substantive requirements must be ascertained through procedures that offer all of the guarantees of protection of the rights to life and self-determination provided for by the different regulations of the aforementioned countries, including, for example, clinical-psychological counselling to ensure autonomy of choice as well as preventive and ex-post control commission on compliance with substantive and procedural requirements. No law or ruling provided for the introduction of policies aimed at eliminating, before executing EAS, the socio-economic causes that led to the request to die.

Perspective

The framework regulating EAS should be integrated with policies and measures to guarantee favorable family and socio-economic conditions, offer full access to palliative care, and allow free and equal decision-making.
本文旨在反思立法者是否应该实施实质性限制,以及应该引入哪些程序规则,以期使安乐死或协助自杀(EAS)合法化,以保障精神病患者和其他患者的健康和自主权。方法:我们分析并比较了EAS合法的九个欧洲国家(荷兰、比利时、卢森堡、奥地利、葡萄牙、西班牙、意大利、瑞士和德国)的规则。讨论过去几年来,越来越多的国家实施或引入了关于紧急医疗服务的法规,这使我们认为:(a)实质性要求不应降低,例如,允许健康的人获得紧急医疗服务;(b)必须通过程序确定实质性要求,这些程序提供上述国家不同条例所规定的保护生命权和自决权的一切保障,例如包括临床-心理咨询,以确保自主选择,以及预防和事后管制委员会遵守实质性和程序性要求。没有任何法律或裁决规定采取旨在在执行紧急安乐死之前消除导致请求死亡的社会经济原因的政策。缓和治疗框架应与政策和措施相结合,以保证有利的家庭和社会经济条件,提供充分的姑息治疗机会,并允许自由和平等的决策。
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引用次数: 0
Cadaver dissection and biohazard risks under the specter of bioethics 生物伦理下的尸体解剖和生物危害风险
Q3 Medicine Pub Date : 2025-01-01 DOI: 10.1016/j.jemep.2025.101126
M. Pettiti , L. Nogueira , L. Lupi , O. Hamel
The use of fresh, unembalmed specimens is an essential source for anatomy laboratories in France, and raises the preliminary question of the biological risks associated with their handling. In the context of anatomical work, this exposure is major and the risk concerns all recipients of cadavers: anatomists and researchers, as well as students and laboratory technicians, all of whom are required to handle a freshly deceased person. In view of this, we wondered if the regulations governing the body donation for scientific purposes, recently included in the French bioethics laws, have sufficiently taken this risk into account, and what is really the extent of this risk when we explore the literature.
Data on the prevalence of infections on anatomical models is disparate, dating back to the last century. The persistence of pathogen viability after death, as described in the literature, does not allow us to reach a scientific consensus on the absence of postmortem contagiousness. The lack of obligation to test bodies prior to anatomical work, despite the risks of accidental injury inherent in handling sharp objects or splashing
human fluids, could lead to infected bodies being made available, without the knowledge of users. The need to incorporate “biological risk prevention” measures linked to anatomical work into the bioethics laws that have governed body donations since 2021 should also be raised, given that the few studies in this field show a wide disparity in the way these risks are understood and managed. Finally, promoting studies to provide solid scientific evidence on the risks of post-mortem transmission of infectious diseases on bodies kept in cold storage for scientific and educational purposes should be encouraged, to provide a clear and definitive answer to the question of post-mortem contagiousness
使用新鲜的、未经防腐处理的标本是法国解剖学实验室的一个重要来源,并提出了与处理这些标本相关的生物风险的初步问题。在解剖工作的背景下,这种接触是主要的,风险涉及到所有尸体的接受者:解剖学家和研究人员,以及学生和实验室技术人员,他们都需要处理一个刚刚死去的人。鉴于此,我们想知道,最近纳入法国生物伦理法的关于科学目的的遗体捐赠的规定是否充分考虑到了这种风险,以及当我们研究文献时,这种风险的真正程度是什么。从上个世纪开始,解剖学模型上感染流行率的数据各不相同。正如文献中所描述的那样,死亡后病原体生存能力的持续存在,使我们无法就没有死后传染性达成科学共识。尽管处理尖锐物体或溅起人体体液固有的意外伤害风险,但没有义务在解剖工作之前对尸体进行检测,这可能导致在用户不知情的情况下提供受感染的尸体。鉴于该领域的少数研究表明,人们对这些风险的理解和管理方式存在很大差异,因此还应提出将与解剖工作相关的“生物风险预防”措施纳入2021年以来管理遗体捐赠的生物伦理法的必要性。最后,应鼓励促进研究,就为科学和教育目的而冷藏的尸体在死后传播传染病的风险提供确凿的科学证据,从而为死后传染问题提供明确和明确的答案
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引用次数: 0
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