Pub Date : 2024-03-01DOI: 10.1093/jsxmed/qdae002.137
N. Souayeh, H. Bettaieb, H. Rouis, C. Mbarki, N. Hsayaoui
Sexually transmitted infections (STIs) are a global health problem. Nursing and obstetrics students are the future workers whose role in health education and promotion is undeniable. Hence we became interested in evaluating their knowledge of STIs. The aim of our study was to assess the knowledge, attitude, and practice of nursing and midwifery students regarding sexually transmitted diseases. This was a prospective, cross-sectional, quantitative, and descriptive study, conducted in the Higher Institute of Nursing Sciences of Tunis (ISSIT) and the Higher Institute of Health Sciences and Techniques of Tunis (ESSTST) over the period of to months (March 1st, 2022 to April 30, 2022). The target population of our study included 568 students. The information was collected via a self-administered questionnaire. Our study population sample was mainly composed of women (72%) versus 28% men. The average age of our sample was 21 years old. The majority of students (95%) have already heard of STIs. The main source of information was the academic background of these students (79%), followed by the media (15%) and only 1% comes from the family circle. Students rated their knowledge as fairly good and good in 37% and 34% of cases, respectively. Only 5% admitted having very good knowledge and 2% with zero knowledge. For their knowledge of the modes of transmission of STIs: 98.4% retained vaginal penetration, 69.1% for anal penetration against 40.7% for oral sex. The best-known germ was the human immunodeficiency virus (HIV) (87.8%) followed closely by syphilis (82.9%). The least known agent was Neisseria Gonorrhoeae (Gonococcus), identified only in 28.4% of cases. 65% of the students recognized syphilis as a bacterial infection. However, 34.1% of students in the sample did not know that it can be associated with HIV infection. Most students (52.8%) had no information regarding HPV infection and only a minority of 18.7% knew that there is an HPV vaccine. 7% already had sex and the medium age of their first sexual intercourse was 18, With an average of 1.33 partners during the last 12 months. Only 2% of them had used a condom during their first sexual intercourse with a new partner. 43%had justified the nonuse of condoms with decreased feelings of pleasure, 29% get embarrassed to purchase it, 14%had some difficulties using it, and 14% did not use a condom because they simply wanted to get pregnant. 75%had the intention to use a condom during their first sexual intercourse while 25% did not. The knowledge of health students regarding sexually transmitted infections needs a boost in order to improve the involvement of awareness of the whole population. Besides, they are not taking the necessary measures to avoid sexually transmitted infections for multiple reasons and the lack of knowledge might be the main cause. No.
{"title":"(151) Knowledge, Attitude, and Practice of Nursing and Midwifery Students Regarding Sexually Transmitted Infections","authors":"N. Souayeh, H. Bettaieb, H. Rouis, C. Mbarki, N. Hsayaoui","doi":"10.1093/jsxmed/qdae002.137","DOIUrl":"https://doi.org/10.1093/jsxmed/qdae002.137","url":null,"abstract":"\u0000 \u0000 \u0000 Sexually transmitted infections (STIs) are a global health problem. Nursing and obstetrics students are the future workers whose role in health education and promotion is undeniable. Hence we became interested in evaluating their knowledge of STIs.\u0000 \u0000 \u0000 \u0000 The aim of our study was to assess the knowledge, attitude, and practice of nursing and midwifery students regarding sexually transmitted diseases.\u0000 \u0000 \u0000 \u0000 This was a prospective, cross-sectional, quantitative, and descriptive study, conducted in the Higher Institute of Nursing Sciences of Tunis (ISSIT) and the Higher Institute of Health Sciences and Techniques of Tunis (ESSTST) over the period of to months (March 1st, 2022 to April 30, 2022). The target population of our study included 568 students. The information was collected via a self-administered questionnaire.\u0000 \u0000 \u0000 \u0000 Our study population sample was mainly composed of women (72%) versus 28% men. The average age of our sample was 21 years old. The majority of students (95%) have already heard of STIs. The main source of information was the academic background of these students (79%), followed by the media (15%) and only 1% comes from the family circle. Students rated their knowledge as fairly good and good in 37% and 34% of cases, respectively. Only 5% admitted having very good knowledge and 2% with zero knowledge. For their knowledge of the modes of transmission of STIs: 98.4% retained vaginal penetration, 69.1% for anal penetration against 40.7% for oral sex. The best-known germ was the human immunodeficiency virus (HIV) (87.8%) followed closely by syphilis (82.9%). The least known agent was Neisseria Gonorrhoeae (Gonococcus), identified only in 28.4% of cases. 65% of the students recognized syphilis as a bacterial infection. However, 34.1% of students in the sample did not know that it can be associated with HIV infection. Most students (52.8%) had no information regarding HPV infection and only a minority of 18.7% knew that there is an HPV vaccine. 7% already had sex and the medium age of their first sexual intercourse was 18, With an average of 1.33 partners during the last 12 months. Only 2% of them had used a condom during their first sexual intercourse with a new partner. 43%had justified the nonuse of condoms with decreased feelings of pleasure, 29% get embarrassed to purchase it, 14%had some difficulties using it, and 14% did not use a condom because they simply wanted to get pregnant. 75%had the intention to use a condom during their first sexual intercourse while 25% did not.\u0000 \u0000 \u0000 \u0000 The knowledge of health students regarding sexually transmitted infections needs a boost in order to improve the involvement of awareness of the whole population. Besides, they are not taking the necessary measures to avoid sexually transmitted infections for multiple reasons and the lack of knowledge might be the main cause.\u0000 \u0000 \u0000 \u0000 No.\u0000","PeriodicalId":377411,"journal":{"name":"The Journal of Sexual Medicine","volume":"57 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140087233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-01DOI: 10.1093/jsxmed/qdae002.089
M. Savira, W. Atmoko
Ischemic priapism (IP) is a prolonged undesired erection that accounts for >95% of all priapism episodes. Like compartment syndrome, it is characterized by diminished corporal blood flow and can lead to corporal fibrosis, penile shortening, and refractory erectile dysfunction. Penile prosthesis (PP) implantation is the treatment option in IP to treat the priapic episode and to preserve erectile function. However, no standardization exists regarding the optimal timing of PP implantation surgery. The present review aims to systematically analyse the literature comparing early and delayed PP implantation in patients with IP. A systematic search on PubMed, Scopus, and EMBASE databases were searched from inception to July 1st, 2023 and followed by hand searching. All the steps were performed according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines. We assess the quality of evidence and the risk of bias in each included study. Three retrospective cohort studies comprising 199 subjects were included in this systematic review. All studies have different definitions of the timing of early PP implantation, ranging from within one week to ≤6 months from the onset of priapism. Despite different types of PP used, all studies agreed that early PP implantation results in lower intraoperative complications, such as corporeal perforation and urethral injury, greater preservation of penile length and girth, and a lower rate of prosthetic revision. On the other hand, the delayed insertion was linked to a longer surgical time because of challenges brought on by fibrotic tissue, with most of them also requiring a smaller cylinder. In regards to post-operative complication, the majority of studies demonstrated that delayed implantation would result in a higher rate of complication rate; however, one study demonstrated that early PP implantation had a higher likelihood of prosthesis erosion and infection, which was believed due to a higher rate of bacterial invasion during the earlier shunt surgeries. The majority of current evidence favours early penile prosthesis insertion in term of lower complication rate for IP, especially the intraoperative complication, for IP, compared to the delayed implantation. Nevertheless, better quality evidence is still needed from RCT to determine the exact timing for early implantation, patient selection, and the best penile prosthesis types. No.
{"title":"(098) Does Early Implantation of Penile Prosthesis for Ischemic Priapism Associated with Decreased Complication Rate? A Systematic Review of Literature","authors":"M. Savira, W. Atmoko","doi":"10.1093/jsxmed/qdae002.089","DOIUrl":"https://doi.org/10.1093/jsxmed/qdae002.089","url":null,"abstract":"\u0000 \u0000 \u0000 Ischemic priapism (IP) is a prolonged undesired erection that accounts for >95% of all priapism episodes. Like compartment syndrome, it is characterized by diminished corporal blood flow and can lead to corporal fibrosis, penile shortening, and refractory erectile dysfunction. Penile prosthesis (PP) implantation is the treatment option in IP to treat the priapic episode and to preserve erectile function. However, no standardization exists regarding the optimal timing of PP implantation surgery.\u0000 \u0000 \u0000 \u0000 The present review aims to systematically analyse the literature comparing early and delayed PP implantation in patients with IP.\u0000 \u0000 \u0000 \u0000 A systematic search on PubMed, Scopus, and EMBASE databases were searched from inception to July 1st, 2023 and followed by hand searching. All the steps were performed according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines. We assess the quality of evidence and the risk of bias in each included study.\u0000 \u0000 \u0000 \u0000 Three retrospective cohort studies comprising 199 subjects were included in this systematic review. All studies have different definitions of the timing of early PP implantation, ranging from within one week to ≤6 months from the onset of priapism. Despite different types of PP used, all studies agreed that early PP implantation results in lower intraoperative complications, such as corporeal perforation and urethral injury, greater preservation of penile length and girth, and a lower rate of prosthetic revision. On the other hand, the delayed insertion was linked to a longer surgical time because of challenges brought on by fibrotic tissue, with most of them also requiring a smaller cylinder. In regards to post-operative complication, the majority of studies demonstrated that delayed implantation would result in a higher rate of complication rate; however, one study demonstrated that early PP implantation had a higher likelihood of prosthesis erosion and infection, which was believed due to a higher rate of bacterial invasion during the earlier shunt surgeries.\u0000 \u0000 \u0000 \u0000 The majority of current evidence favours early penile prosthesis insertion in term of lower complication rate for IP, especially the intraoperative complication, for IP, compared to the delayed implantation. Nevertheless, better quality evidence is still needed from RCT to determine the exact timing for early implantation, patient selection, and the best penile prosthesis types.\u0000 \u0000 \u0000 \u0000 No.\u0000","PeriodicalId":377411,"journal":{"name":"The Journal of Sexual Medicine","volume":"112 43","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140089409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-01DOI: 10.1093/jsxmed/qdae002.184
M. Mahdi, K. Khalafalla, M. Arafa, H. Elbardisi, A. Majzoub
Premature ejaculation (PE) is one of the most common sexual disorders that negatively impacts couple’s satisfaction. Varicocele on the other hand is a highly prevalent condition affecting men population. A higher incidence of PE is observed among patients with varicocele, which incited several authors to evaluate the possible correlation between varicocele and PE. Others went beyond that to investigate whether varicocele repair can lead to an improvement in PE. To systematically review the literature for all the studies exploring the relationship between PE and varicocele. A systemic review was performed utilizing (PRISMA) statement. The PubMed, Google scholar and Scopus databases were used to look for articles published up to June 2023 using the appropriate keywords. Articles reporting an association between the presence of varicocele and PE and exploring changes in ejaculation latency time after varicocele correction were included. Data including study design, sample size, varicocele details, PE diagnostic method, outcome measured and tools used to measure it were collected. The Newcastle-Ottawa scale was used for assessing the quality of the included studies. A total of eight studies were identified, two of them were retrospective and six were prospective. Intravaginal ejaculation latency time (IELT) was used as a diagnostic tool for PE in 5 studies, Premature Ejaculation Diagnostic Tool (PEDT) in 1 study, Chinese Index of Sexual Function for Premature Ejaculation-5 (CIPE-5) scores in 1 study, and subjective assessment in 2 studies. Two studies looked for the prevalence of PE among patients with and without varicocele. Both studies showed a significantly higher frequency of PE among varicocele patients. Whereas six studies evaluated the improvement in ejaculatory function after varicocelectomy; five of them revealed a statistically significant improvement. Quality check: only one study was of strong quality while the remaining 7 studies were of fair quality. Limited evidence suggests the presence of positive relation between varicocele and PE. The small number of studies and patients, lack of enough prospective clinical trials, short term follow up, heterogenous study design and absence or diversity in the diagnostic tools used prevent our ability to build strong evidence. For the purpose of supporting the relation and validate it, further prospective studies on a larger number of patients with long-term follow up are needed to reach a solid verdict. No.
早泄（PE）是最常见的性功能障碍之一，会对夫妻双方的满意度产生负面影响。精索静脉曲张则是影响男性人群的一种高发疾病。据观察，精索静脉曲张患者的早泄发生率较高，这促使一些学者对精索静脉曲张与早泄之间可能存在的相关性进行评估。还有一些学者进一步研究了精索静脉曲张修复术是否能改善 PE。 系统回顾所有探讨 PE 与精索静脉曲张关系的研究文献。 我们利用（PRISMA）声明进行了系统性回顾。利用 PubMed、Google scholar 和 Scopus 数据库，使用适当的关键词查找截至 2023 年 6 月发表的文章。其中包括报告精索静脉曲张与 PE 之间存在关联的文章，以及探讨精索静脉曲张矫正后射精潜伏时间变化的文章。收集的数据包括研究设计、样本大小、精索静脉曲张详情、精索静脉曲张诊断方法、测量结果和测量工具。纽卡斯尔-渥太华量表用于评估纳入研究的质量。 共确定了 8 项研究，其中 2 项为回顾性研究，6 项为前瞻性研究。5项研究使用阴道内射精潜伏时间（IELT）作为PE的诊断工具，1项研究使用早泄诊断工具（PEDT），1项研究使用中国早泄性功能指数-5（CIPE-5）评分，2项研究使用主观评估。两项研究调查了有精索静脉曲张和无精索静脉曲张患者的早泄发生率。两项研究均显示，精索静脉曲张患者的早泄发生率明显更高。六项研究对精索静脉曲张切除术后射精功能的改善情况进行了评估，其中五项研究显示射精功能的改善在统计学上有显著意义。质量检查：只有一项研究的质量较高，其余 7 项研究的质量一般。 有限的证据表明精索静脉曲张与 PE 之间存在正相关。由于研究和患者数量较少、缺乏足够的前瞻性临床试验、随访时间较短、研究设计不尽相同以及所使用诊断工具的缺乏或多样性，我们无法获得有力的证据。为了支持和验证这种关系，需要对更多患者进行进一步的前瞻性研究和长期随访，以得出可靠的结论。 不
{"title":"(207) Premature Ejaculation and Varicocele, are they Associated? Systematic Review","authors":"M. Mahdi, K. Khalafalla, M. Arafa, H. Elbardisi, A. Majzoub","doi":"10.1093/jsxmed/qdae002.184","DOIUrl":"https://doi.org/10.1093/jsxmed/qdae002.184","url":null,"abstract":"\u0000 \u0000 \u0000 Premature ejaculation (PE) is one of the most common sexual disorders that negatively impacts couple’s satisfaction. Varicocele on the other hand is a highly prevalent condition affecting men population. A higher incidence of PE is observed among patients with varicocele, which incited several authors to evaluate the possible correlation between varicocele and PE. Others went beyond that to investigate whether varicocele repair can lead to an improvement in PE.\u0000 \u0000 \u0000 \u0000 To systematically review the literature for all the studies exploring the relationship between PE and varicocele.\u0000 \u0000 \u0000 \u0000 A systemic review was performed utilizing (PRISMA) statement. The PubMed, Google scholar and Scopus databases were used to look for articles published up to June 2023 using the appropriate keywords. Articles reporting an association between the presence of varicocele and PE and exploring changes in ejaculation latency time after varicocele correction were included. Data including study design, sample size, varicocele details, PE diagnostic method, outcome measured and tools used to measure it were collected. The Newcastle-Ottawa scale was used for assessing the quality of the included studies.\u0000 \u0000 \u0000 \u0000 A total of eight studies were identified, two of them were retrospective and six were prospective. Intravaginal ejaculation latency time (IELT) was used as a diagnostic tool for PE in 5 studies, Premature Ejaculation Diagnostic Tool (PEDT) in 1 study, Chinese Index of Sexual Function for Premature Ejaculation-5 (CIPE-5) scores in 1 study, and subjective assessment in 2 studies. Two studies looked for the prevalence of PE among patients with and without varicocele. Both studies showed a significantly higher frequency of PE among varicocele patients. Whereas six studies evaluated the improvement in ejaculatory function after varicocelectomy; five of them revealed a statistically significant improvement. Quality check: only one study was of strong quality while the remaining 7 studies were of fair quality.\u0000 \u0000 \u0000 \u0000 Limited evidence suggests the presence of positive relation between varicocele and PE. The small number of studies and patients, lack of enough prospective clinical trials, short term follow up, heterogenous study design and absence or diversity in the diagnostic tools used prevent our ability to build strong evidence. For the purpose of supporting the relation and validate it, further prospective studies on a larger number of patients with long-term follow up are needed to reach a solid verdict.\u0000 \u0000 \u0000 \u0000 No.\u0000 \u0000","PeriodicalId":377411,"journal":{"name":"The Journal of Sexual Medicine","volume":" 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140091591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-01DOI: 10.1093/jsxmed/qdae002.168
D. Choucroun
We are experiencing a new profound societal transformation: the contraceptive crisis, attributed to the side-effects of hormonal contraception (since 2012) meets the rise of digital technologies. People seem to reject even the slightest risk of hormonal contraception, in favor of entrusting their intimitate data to online companies. But is the rejection of hormonal contraception really du to its iatrogenic risks? Hormonal contraception is 60 years old and its risks are not new and already known, and people don't hesitate to take far greater risks in all areas of their lives: sexual practices and encounters with strangers, sports activities, driving motor vehicles, tobacco, alcohol, etc... In view of this paradox, we will attempt to assess the advantages of digital contraception over medical contraception. Drawing up an inventory of scientific research on digital contraception Know the real reliability of digital contraception and menstruations trackers Know the real risks for health and the other risks of these trackers Using the information obtained, be able to communicate and inform users as objectively as possible Literature review on PubMed and Google Scholar for the last 12 months with the keywords: digital contraception, menstruations applications, period tracking applications, menstruations applications and data priv0acy. PubMed reports only six relevant studies about digital period trackers: these are concerned solely with the prospect of pregnancy or with the interest of data that might suggest a pathology such as Polycystic ovary syndrome, endometriosis or some other conditions. One study report that further research is needed to assess contents and its use. It is interesting to note that "data privacy" gives here no result, no result for "digital contraception" either. "Digital contraception" is still not a buzzword on Google Scholar" with only one relevant survey, and various research studies on period trackers report a lack of reliability in informations purporting to be scientific. What's most worrying is that the period trackers use external services for data storage with no guarantee of data protection. Literature reports that users are falsely reassured about their privacy by a non-human actor and are not aware that their data can be sold to mercantile companies. Little known consequences are also about ecology with the pollution of the data centers and about reproductive rights by monitoring periods of amenorrhea. There are many blinds spots for users when it comes to menstruations trackers, and it is surprising to see people trusting commercial device, about their health, without any independent scientific guarantee. Thus, we observe a loss of trust for health care providers and we have to understand the current situation in sexual and reproductive health: May be we have to ask not why don't people use medical contraception, but why do people use medical contraception? What are the key factors
{"title":"(190) Digital Contraception: Effectiveness, Data Privacy, Reproductives Rights","authors":"D. Choucroun","doi":"10.1093/jsxmed/qdae002.168","DOIUrl":"https://doi.org/10.1093/jsxmed/qdae002.168","url":null,"abstract":"\u0000 \u0000 \u0000 We are experiencing a new profound societal transformation: the contraceptive crisis, attributed to the side-effects of hormonal contraception (since 2012) meets the rise of digital technologies. People seem to reject even the slightest risk of hormonal contraception, in favor of entrusting their intimitate data to online companies. But is the rejection of hormonal contraception really du to its iatrogenic risks? Hormonal contraception is 60 years old and its risks are not new and already known, and people don't hesitate to take far greater risks in all areas of their lives: sexual practices and encounters with strangers, sports activities, driving motor vehicles, tobacco, alcohol, etc... In view of this paradox, we will attempt to assess the advantages of digital contraception over medical contraception.\u0000 \u0000 \u0000 \u0000 Drawing up an inventory of scientific research on digital contraception Know the real reliability of digital contraception and menstruations trackers Know the real risks for health and the other risks of these trackers Using the information obtained, be able to communicate and inform users as objectively as possible\u0000 \u0000 \u0000 \u0000 Literature review on PubMed and Google Scholar for the last 12 months with the keywords: digital contraception, menstruations applications, period tracking applications, menstruations applications and data priv0acy.\u0000 \u0000 \u0000 \u0000 PubMed reports only six relevant studies about digital period trackers: these are concerned solely with the prospect of pregnancy or with the interest of data that might suggest a pathology such as Polycystic ovary syndrome, endometriosis or some other conditions. One study report that further research is needed to assess contents and its use. It is interesting to note that \"data privacy\" gives here no result, no result for \"digital contraception\" either. \"Digital contraception\" is still not a buzzword on Google Scholar\" with only one relevant survey, and various research studies on period trackers report a lack of reliability in informations purporting to be scientific. What's most worrying is that the period trackers use external services for data storage with no guarantee of data protection. Literature reports that users are falsely reassured about their privacy by a non-human actor and are not aware that their data can be sold to mercantile companies. Little known consequences are also about ecology with the pollution of the data centers and about reproductive rights by monitoring periods of amenorrhea.\u0000 \u0000 \u0000 \u0000 There are many blinds spots for users when it comes to menstruations trackers, and it is surprising to see people trusting commercial device, about their health, without any independent scientific guarantee. Thus, we observe a loss of trust for health care providers and we have to understand the current situation in sexual and reproductive health: May be we have to ask not why don't people use medical contraception, but why do people use medical contraception? What are the key factors ","PeriodicalId":377411,"journal":{"name":"The Journal of Sexual Medicine","volume":" 526","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140092373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-01DOI: 10.1093/jsxmed/qdae002.124
C. Krejčová, K. Klapilová, K. Bártová
Asexuality is usually defined as a lack of sexual attraction to others; however, asexuals may engage in sexual activity. Previous research has shown that asexuals are less likely to engage in sexual intercourse and masturbation than allosexuals. But information about detailed aspects of sexual behavior among asexuals is still scattered. The main aim of this study was to map the sexual behavior of asexual men and women. In addition, the usage and pleasurability of various sex positions in asexuals were explored. Participants were recruited in 2020 via a sociodemographic agency using computer-assisted web interviewing software. Stratified random sampling with quotas on Czech nationality, region, size of the place of residence, sex, age, and education was applied. A representative sample of 1,616 adult men (n = 806; 21–85 years; mage = 50.65; SD = 15.52) and women (n = 810; 20–91 years; mage = 50,62; SD = 16.15) answered questions about selected dimensions of sexual behavior in the last year. Approximately 2.1 % (n = 17) of men and 1.6 % (n = 13) of women indicated they were asexual. Preliminary results showed that asexual women had more sexual intercourse per month in the last year (7–10 vs. 4–6 occasions) compared to asexual men. Asexual women and men had the same average number of orgasms per month achieved during partner sexual activities with a long-term partner in the last year (2–3x). Asexual men had a stronger desire for sexual activity with a partner per month (7–10x vs. 4–6x), a higher number of masturbations per month and orgasms achieved during masturbation (2–3x vs. none), and a higher number of searches for erotic/pornographic materials per month in the last year (2–3x vs. none). Asexual women expressed a higher preference for sexual activities with a partner, whereas asexual men expressed a similar preference for sexual activities with a partner and masturbation. Based on median frequencies of sexual positions used in the last year, asexual women reported engaging in most penile-vaginal sexual positions (1–2x) but not sexual positions with oral-genital contact. Among asexual men, face-to-face/male above was the only reported sexual position used in the last year (1–2x). Asexual women and men reported face-to-face/male above, face-to-face/female above, and kneeling/rear entry as the most pleasurable sexual positions. Consistent with previous research, we found that asexuals may engage in sexual intercourse and masturbation. Asexual women were more likely to engage in sexual intercourse with various penile-vaginal sexual positions. In contrast, asexual men experienced stronger sexual desire and were more likely to engage in masturbation. No discrepancy was found in the rated pleasurability of several sexual positions. Thus, our results suggest that asexual women may prefer sexual activities with a partner, whereas asexual men may prefer autosexual activities. No.
{"title":"(136) Sexual Behavior among Asexual Men and Women in the Czech Population","authors":"C. Krejčová, K. Klapilová, K. Bártová","doi":"10.1093/jsxmed/qdae002.124","DOIUrl":"https://doi.org/10.1093/jsxmed/qdae002.124","url":null,"abstract":"\u0000 \u0000 \u0000 Asexuality is usually defined as a lack of sexual attraction to others; however, asexuals may engage in sexual activity. Previous research has shown that asexuals are less likely to engage in sexual intercourse and masturbation than allosexuals. But information about detailed aspects of sexual behavior among asexuals is still scattered.\u0000 \u0000 \u0000 \u0000 The main aim of this study was to map the sexual behavior of asexual men and women. In addition, the usage and pleasurability of various sex positions in asexuals were explored.\u0000 \u0000 \u0000 \u0000 Participants were recruited in 2020 via a sociodemographic agency using computer-assisted web interviewing software. Stratified random sampling with quotas on Czech nationality, region, size of the place of residence, sex, age, and education was applied. A representative sample of 1,616 adult men (n = 806; 21–85 years; mage = 50.65; SD = 15.52) and women (n = 810; 20–91 years; mage = 50,62; SD = 16.15) answered questions about selected dimensions of sexual behavior in the last year.\u0000 \u0000 \u0000 \u0000 Approximately 2.1 % (n = 17) of men and 1.6 % (n = 13) of women indicated they were asexual. Preliminary results showed that asexual women had more sexual intercourse per month in the last year (7–10 vs. 4–6 occasions) compared to asexual men. Asexual women and men had the same average number of orgasms per month achieved during partner sexual activities with a long-term partner in the last year (2–3x). Asexual men had a stronger desire for sexual activity with a partner per month (7–10x vs. 4–6x), a higher number of masturbations per month and orgasms achieved during masturbation (2–3x vs. none), and a higher number of searches for erotic/pornographic materials per month in the last year (2–3x vs. none). Asexual women expressed a higher preference for sexual activities with a partner, whereas asexual men expressed a similar preference for sexual activities with a partner and masturbation. Based on median frequencies of sexual positions used in the last year, asexual women reported engaging in most penile-vaginal sexual positions (1–2x) but not sexual positions with oral-genital contact. Among asexual men, face-to-face/male above was the only reported sexual position used in the last year (1–2x). Asexual women and men reported face-to-face/male above, face-to-face/female above, and kneeling/rear entry as the most pleasurable sexual positions.\u0000 \u0000 \u0000 \u0000 Consistent with previous research, we found that asexuals may engage in sexual intercourse and masturbation. Asexual women were more likely to engage in sexual intercourse with various penile-vaginal sexual positions. In contrast, asexual men experienced stronger sexual desire and were more likely to engage in masturbation. No discrepancy was found in the rated pleasurability of several sexual positions. Thus, our results suggest that asexual women may prefer sexual activities with a partner, whereas asexual men may prefer autosexual activities.\u0000 \u0000 \u0000 \u0000 No.\u0000","PeriodicalId":377411,"journal":{"name":"The Journal of Sexual Medicine","volume":" June","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140092689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-01DOI: 10.1093/jsxmed/qdae002.211
M. Abdel-Fattah, T. Alzahrani, M. Abdel-Fatah, M. Aljohani, A. Abolhasan, H. Eltholoth, A. Amer
Sperm retrieval in NOA patients remain to be the only hope for these patients for fatherhood using assisted reproductive techniques. Micro-TESE is the gold standard with the best retrieval rate. Microsurgical facilities are not available at every center and conventional TESE techniques are not standardized between different centers. Our aim is To improve the spermatogenic function of NOA patients to enable the appearance of sperm in their ejaculate or to improve the chances of a successful retrieval from the testis for ICSI and To optimize and standardize our conventional TESE technique Over last 7 years 94 cases of NOA patients were subjected to conventional TESE. We Exclude the cases of Obstructive Azoospermia, Cases with abnormal chromosomal analysis were referred for higher center for genetic counselling and diagnosis. Laboratory workup including at least two semen samples, hormonal valuation (FSH, LH, Prolactin, Testosterone) and chromosomal analysis (Karyotyping and Testing for Y chromosome micro-deletions. Pre-TESE medical Treatment: included Clomiphene citrate: 50 mg OD for 3–6 months, Anti-oxidant therapy (Vitamin E 200mg BID and Vitamin C, 1 gm, OD). 6 biopsies from each testis: upper pole 2(medial &Lateral), mid zone 2 (medial & Lateral), lower pole 2(medial &Lateral). Separate biopsy from each testis was sent for definitive histopathological correlation. Experienced embryologist attends each procedure examining each biopsy until sperms are retrieved. Samples taken were centrifuged and re-examined at lab for any missed sperm sperm retrieval was successful in 38patients (40.4%). All cases were done as day case No single case of wound infection or intra-testicular hematoma.Post-operative pain was tolerable and managed by paracetamol ±NSAID Negative cases for sperms were continued on higher dose of CC and referred for microTESE Though of low-evidence, empiric Pre-TESE enhancement of spermatogenesis should be attempted whenever possible and after proper patients counselling. This systematic anatomical approach for biopsies yielded high SRR compared to other conventional TESE. Exact localization of + ve testicular site and side If patient needed Re-do TESE for more sperms in the future. Although micro TESE remains to be the best modality for SR in NOA, in our hands and in canters without Micro-TESE facilities, applying this standardized technique with pre-operative hormonal manipulation yields accepted rate of sperm retrieval No.
{"title":"(244) Optimization of Sperm Retrieval in Non-Obstructive Azoospermic Patients using Conventional TESE","authors":"M. Abdel-Fattah, T. Alzahrani, M. Abdel-Fatah, M. Aljohani, A. Abolhasan, H. Eltholoth, A. Amer","doi":"10.1093/jsxmed/qdae002.211","DOIUrl":"https://doi.org/10.1093/jsxmed/qdae002.211","url":null,"abstract":"\u0000 \u0000 \u0000 Sperm retrieval in NOA patients remain to be the only hope for these patients for fatherhood using assisted reproductive techniques. Micro-TESE is the gold standard with the best retrieval rate. Microsurgical facilities are not available at every center and conventional TESE techniques are not standardized between different centers.\u0000 \u0000 \u0000 \u0000 Our aim is To improve the spermatogenic function of NOA patients to enable the appearance of sperm in their ejaculate or to improve the chances of a successful retrieval from the testis for ICSI and To optimize and standardize our conventional TESE technique\u0000 \u0000 \u0000 \u0000 Over last 7 years 94 cases of NOA patients were subjected to conventional TESE. We Exclude the cases of Obstructive Azoospermia, Cases with abnormal chromosomal analysis were referred for higher center for genetic counselling and diagnosis. Laboratory workup including at least two semen samples, hormonal valuation (FSH, LH, Prolactin, Testosterone) and chromosomal analysis (Karyotyping and Testing for Y chromosome micro-deletions. Pre-TESE medical Treatment: included Clomiphene citrate: 50 mg OD for 3–6 months, Anti-oxidant therapy (Vitamin E 200mg BID and Vitamin C, 1 gm, OD). 6 biopsies from each testis: upper pole 2(medial &Lateral), mid zone 2 (medial & Lateral), lower pole 2(medial &Lateral). Separate biopsy from each testis was sent for definitive histopathological correlation. Experienced embryologist attends each procedure examining each biopsy until sperms are retrieved. Samples taken were centrifuged and re-examined at lab for any missed sperm\u0000 \u0000 \u0000 \u0000 sperm retrieval was successful in 38patients (40.4%). All cases were done as day case No single case of wound infection or intra-testicular hematoma.Post-operative pain was tolerable and managed by paracetamol ±NSAID Negative cases for sperms were continued on higher dose of CC and referred for microTESE\u0000 \u0000 \u0000 \u0000 Though of low-evidence, empiric Pre-TESE enhancement of spermatogenesis should be attempted whenever possible and after proper patients counselling. This systematic anatomical approach for biopsies yielded high SRR compared to other conventional TESE. Exact localization of + ve testicular site and side If patient needed Re-do TESE for more sperms in the future. Although micro TESE remains to be the best modality for SR in NOA, in our hands and in canters without Micro-TESE facilities, applying this standardized technique with pre-operative hormonal manipulation yields accepted rate of sperm retrieval\u0000 \u0000 \u0000 \u0000 No.\u0000","PeriodicalId":377411,"journal":{"name":"The Journal of Sexual Medicine","volume":" December","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140092719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-01DOI: 10.1093/jsxmed/qdae002.111
W. Kinnaird, M. Kirby, P. Schartau, V. Jenkins, S. Allen, H. Payne
The physical and psychological health benefits of sexual activity are well documented. However, sexual needs in people with disabilities are often unrecognised and they are less likely to access professional support when problems arise. Almost all prostate cancer (PCa) treatments are associated with sexual side effects that can have negative effects on sexual well-being. To explore the impact disability has on PCa patients' experiences of sexual dysfunction and accessing support. An anonymous online survey was distributed to men with PCa in collaboration with the charity Prostate Cancer UK. Questions focused on participants’ experience of sexual dysfunction and the level of support they received. The focus of the current sub-analysis was on participants who self-reported any kind of disability. Chi-square testing was used for categorical variable analysis. 654 out of 893 adult participants (73.2%) reported having a diagnosis of prostate cancer. Of those 95 (14.5%) self-reported having a disability, 553 (84.6%) reported not having a disability, and 6 (0.9%) said they would ‘prefer not to say’. Physical and psychological sexual problems were common among men with self-reported disabilities, with more than 50% reporting sexual dysfunction in 9 out of 13 domains. They were more likely to report sexual dysfunction than men with no disability in 11 out of those 13 domains, reaching the level of significance in five of those (p<.05). [Fig 1] Sexual activity was rated as ‘fairly/very important’ by 77.9% (n=74) of men with a disability. Further, 60.0% (n=57) reported ‘sexual problems’ to be in their top three current concerns, the highest ranked concern from a list of 15 categories. There was no significant difference in these two results when compared with those for men who did not self-report a disability (p=.90 & p=.68). Despite this, men with a disability were significantly less likely to have discussed the sexual side effects of PCa treatment with a healthcare professional (HCP) (44.2% vs 65.3%, p<.05). Of the men who did discuss sexual side effects, only a minority in both groups were offered a referral on to a specialist clinic, with no significant difference between the groups (27.6% vs 29.9%, p=.71). Men with a disability reported lower levels of satisfaction in each of five statements assessing satisfaction with support for sexual side effects, reaching the level of significance in four (p<0.05) [Fig 2]. This study is the first to report on disability and men’s experience of sexual dysfunction associated with PCa. Our findings suggest wide-ranging physical and psychological sexual side effects are common and distressing among men with disabilities. Sexual activity is equally as important to men with disabilities but they are less likely to access support through HCPs. This results in high levels of dissatisfaction with care. The results suggest men with disabilities face additional barriers to accessing sexual s
{"title":"(122) Disability and Men’s Experience of Sexual Dysfunction Associated with Prostate Cancer","authors":"W. Kinnaird, M. Kirby, P. Schartau, V. Jenkins, S. Allen, H. Payne","doi":"10.1093/jsxmed/qdae002.111","DOIUrl":"https://doi.org/10.1093/jsxmed/qdae002.111","url":null,"abstract":"\u0000 \u0000 \u0000 The physical and psychological health benefits of sexual activity are well documented. However, sexual needs in people with disabilities are often unrecognised and they are less likely to access professional support when problems arise. Almost all prostate cancer (PCa) treatments are associated with sexual side effects that can have negative effects on sexual well-being.\u0000 \u0000 \u0000 \u0000 To explore the impact disability has on PCa patients' experiences of sexual dysfunction and accessing support.\u0000 \u0000 \u0000 \u0000 An anonymous online survey was distributed to men with PCa in collaboration with the charity Prostate Cancer UK. Questions focused on participants’ experience of sexual dysfunction and the level of support they received. The focus of the current sub-analysis was on participants who self-reported any kind of disability. Chi-square testing was used for categorical variable analysis.\u0000 \u0000 \u0000 \u0000 654 out of 893 adult participants (73.2%) reported having a diagnosis of prostate cancer. Of those 95 (14.5%) self-reported having a disability, 553 (84.6%) reported not having a disability, and 6 (0.9%) said they would ‘prefer not to say’. Physical and psychological sexual problems were common among men with self-reported disabilities, with more than 50% reporting sexual dysfunction in 9 out of 13 domains. They were more likely to report sexual dysfunction than men with no disability in 11 out of those 13 domains, reaching the level of significance in five of those (p<.05). [Fig 1] Sexual activity was rated as ‘fairly/very important’ by 77.9% (n=74) of men with a disability. Further, 60.0% (n=57) reported ‘sexual problems’ to be in their top three current concerns, the highest ranked concern from a list of 15 categories. There was no significant difference in these two results when compared with those for men who did not self-report a disability (p=.90 & p=.68). Despite this, men with a disability were significantly less likely to have discussed the sexual side effects of PCa treatment with a healthcare professional (HCP) (44.2% vs 65.3%, p<.05). Of the men who did discuss sexual side effects, only a minority in both groups were offered a referral on to a specialist clinic, with no significant difference between the groups (27.6% vs 29.9%, p=.71). Men with a disability reported lower levels of satisfaction in each of five statements assessing satisfaction with support for sexual side effects, reaching the level of significance in four (p<0.05) [Fig 2].\u0000 \u0000 \u0000 \u0000 This study is the first to report on disability and men’s experience of sexual dysfunction associated with PCa. Our findings suggest wide-ranging physical and psychological sexual side effects are common and distressing among men with disabilities. Sexual activity is equally as important to men with disabilities but they are less likely to access support through HCPs. This results in high levels of dissatisfaction with care. The results suggest men with disabilities face additional barriers to accessing sexual s","PeriodicalId":377411,"journal":{"name":"The Journal of Sexual Medicine","volume":"123 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140276358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-01DOI: 10.1093/jsxmed/qdae002.046
J. Kiesner, C. Bittoni
Research has shown that hormonal contraceptive (HC) use is associated with risk for vulvar pain [1] and vulvodynia [2,3]. Although some literature has focused on combined hormonal contraceptives (CHCs), Bouchard et al [2] found that risk was higher for those using high progestin potency HCs. In addition to increased risk associated with HC use, research also suggests that characteristics of the menstrual cycle (eg., premenstrual symptoms) are associated with risk for vulvodynia [4]. Test for associations between having a diagnosis of vulvodynia (including vestibulodynia) and experiencing vulvar/vaginal, psychological, and physical side effects from OC use. Test for differences in these associations across estroprogestinic OCs, progesterone only OCs, and OCs of an unknown composition (based on self-reports). A sample of 2199 females participated in a larger study on genito-pelvic pain and sexuality and provided data on both HC use and genito-pelvic pain. Efforts were made to recruit a heterogenous sample, with an oversampling of females with genito-pelvic pain. The dependent variable was a dichotomous variable of whether they had ever received a diagnosis of vulvodynia or vestibulodynia. Predictor variables were: ever used each type of OC (analyses conducted separately for estroprogestinic, progesterone only, and unknown type); and experiencing the following side effects associated with each OC type: vulvar pain (dichotomous), vaginal dryness (dichotomous), decreased sexual desire (dichotomous), affective symptoms (sum of dichotomous responses to: anxiety, nervousness, depression, anger, mood swings) and physical symptoms (sum of dichotomous responses to: cramps, back and joint pain, bloating, cellulite, breast discomfort). Three nominal logistic regression analyses were conducted (one for each OC), and a final nominal logistic regression was conducted combining the relevant predictors for each OC into one analysis. Of the 2199 participants, n=673 had never used OCs, n=827 had used them in the past, and n=699 were currently using them. Regarding vulvar/vaginal pain, n=1083 had no vulvar or vaginal pain, n=341 had only vulvar pain, n=194 had only vaginal pain, and n=581 both vulvar and vaginal pain. Finally, regarding diagnoses, n=582 (26%) had a diagnosis of vulvodynia/vestibulodynia (all types combined). Results from the nominal logistic regressions are presented in Tables 1 and 2. Findings of central importance are: having ever used any of the three categories of OCs was associated with increased risk for a diagnosis; vulvar pain and vaginal dryness were the only side effects of OCs that demonstrated a consistent association with increased risk of having a diagnosis; side effects of estroprogestinic OCs were the most strongly associated with increased risk of having a diagnosis; and the effects observed in the first three models remained significant even when all were included in the same final analysis (with the excep
{"title":"(050) Vulvodynia: Risk Associated with Vulvar/Vaginal, Psychological and Physical Side Effects of Oral Contraceptive Use","authors":"J. Kiesner, C. Bittoni","doi":"10.1093/jsxmed/qdae002.046","DOIUrl":"https://doi.org/10.1093/jsxmed/qdae002.046","url":null,"abstract":"\u0000 \u0000 \u0000 Research has shown that hormonal contraceptive (HC) use is associated with risk for vulvar pain [1] and vulvodynia [2,3]. Although some literature has focused on combined hormonal contraceptives (CHCs), Bouchard et al [2] found that risk was higher for those using high progestin potency HCs. In addition to increased risk associated with HC use, research also suggests that characteristics of the menstrual cycle (eg., premenstrual symptoms) are associated with risk for vulvodynia [4].\u0000 \u0000 \u0000 \u0000 Test for associations between having a diagnosis of vulvodynia (including vestibulodynia) and experiencing vulvar/vaginal, psychological, and physical side effects from OC use. Test for differences in these associations across estroprogestinic OCs, progesterone only OCs, and OCs of an unknown composition (based on self-reports).\u0000 \u0000 \u0000 \u0000 A sample of 2199 females participated in a larger study on genito-pelvic pain and sexuality and provided data on both HC use and genito-pelvic pain. Efforts were made to recruit a heterogenous sample, with an oversampling of females with genito-pelvic pain. The dependent variable was a dichotomous variable of whether they had ever received a diagnosis of vulvodynia or vestibulodynia. Predictor variables were: ever used each type of OC (analyses conducted separately for estroprogestinic, progesterone only, and unknown type); and experiencing the following side effects associated with each OC type: vulvar pain (dichotomous), vaginal dryness (dichotomous), decreased sexual desire (dichotomous), affective symptoms (sum of dichotomous responses to: anxiety, nervousness, depression, anger, mood swings) and physical symptoms (sum of dichotomous responses to: cramps, back and joint pain, bloating, cellulite, breast discomfort). Three nominal logistic regression analyses were conducted (one for each OC), and a final nominal logistic regression was conducted combining the relevant predictors for each OC into one analysis.\u0000 \u0000 \u0000 \u0000 Of the 2199 participants, n=673 had never used OCs, n=827 had used them in the past, and n=699 were currently using them. Regarding vulvar/vaginal pain, n=1083 had no vulvar or vaginal pain, n=341 had only vulvar pain, n=194 had only vaginal pain, and n=581 both vulvar and vaginal pain. Finally, regarding diagnoses, n=582 (26%) had a diagnosis of vulvodynia/vestibulodynia (all types combined). Results from the nominal logistic regressions are presented in Tables 1 and 2. Findings of central importance are: having ever used any of the three categories of OCs was associated with increased risk for a diagnosis; vulvar pain and vaginal dryness were the only side effects of OCs that demonstrated a consistent association with increased risk of having a diagnosis; side effects of estroprogestinic OCs were the most strongly associated with increased risk of having a diagnosis; and the effects observed in the first three models remained significant even when all were included in the same final analysis (with the excep","PeriodicalId":377411,"journal":{"name":"The Journal of Sexual Medicine","volume":"93 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140280601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-01DOI: 10.1093/jsxmed/qdae002.106
M. Savira, W. Atmoko
Erectile dysfunction (ED) is common health issues among men with increasing prevalence along with age. With the advancement of technology, the aim of therapy for ED is start to shift in reversing the pathology and not only relieving the symptoms. Platelet-rich plasma (PRP) are one of the regenerative modalities that has gained popularity in many medical disciplines. Many studies have been conducted that favour PRP in improving erectile function. However, no relevant meta-analysis of PRP have been performed to date. A single-arm meta-analysis were conducted to evaluate the outcome of PRP for the treatment of ED based on the data before and after the procedures. We systematically searched PubMed, Embase, Scopus in June 2023 to find the relevant articles based on the Preferred Reporting Items for Systematic Review and Meta-analysis statement. All randomized controlled trials (RCTs), observational, and case control studies in English with 10 or more subjects and a minimum of 1 month follow-up after PRP treatment reporting International Index of Erectile Function-Erectile Function (IIEF-EF) score were included. Pooled analysis on outcomes that were reported in at least 2 studies were performed using RevMan 5.4 and STATA18 with 95% confidence intervals (CIs). We also conduct heterogeneity test and a leave-one-out sensitivity analysis. A total of three RCTs, three observational studies and one case-control study, comprising 236 patients, were included from 183 studies identified. The pooled analysis showed that PRP injection significantly increased the IIEF-EF score by 3.87 (95% CI: 2.92, 4.83, p<0.00001), 3.01 (95% CI: 2.27, 3.74, p<0.0001), 3.29 (95% CI: 2.26, 4.32, p<0.00001), at 1, 3, and 6, months follow-up. Subgroup analysis of IIEF-EF based on the use of PDE5i in the protocol or during follow-up period also found the same finding result. The proportion of patient who met MCID after 6 months of follow of was 70% (95% CI: 59%, 80%). In term of penile hemodynamic, a significant improvement was found in peak systolic velocity and end diastolic velocity at the end-point of follow-up. On contrary, there was no significant improvement were found for IIEF score of intercourse satisfaction and overall satisfaction domain. The most common complication reported were transient subcutaneous bruising. Two cases reported a formation of painless plaque but no other major adverse events were reported. Consistent result was found after a leave-one-out sensitivity analysis. PRP is a promising restorative modality for ED with improvement in IIEF-EF score and penile hemodynamic. However, further studies and human trials are required to confirm the efficacy and durability of this novel treatment as well as to find out the best protocol of administration. No.
{"title":"(117) Is Platelet-Rich Plasma Effective and Safe for Managing Erectile Dysfunction? A Meta-Analysis of Before-After Data from Clinical Studies","authors":"M. Savira, W. Atmoko","doi":"10.1093/jsxmed/qdae002.106","DOIUrl":"https://doi.org/10.1093/jsxmed/qdae002.106","url":null,"abstract":"\u0000 \u0000 \u0000 Erectile dysfunction (ED) is common health issues among men with increasing prevalence along with age. With the advancement of technology, the aim of therapy for ED is start to shift in reversing the pathology and not only relieving the symptoms. Platelet-rich plasma (PRP) are one of the regenerative modalities that has gained popularity in many medical disciplines. Many studies have been conducted that favour PRP in improving erectile function. However, no relevant meta-analysis of PRP have been performed to date.\u0000 \u0000 \u0000 \u0000 A single-arm meta-analysis were conducted to evaluate the outcome of PRP for the treatment of ED based on the data before and after the procedures.\u0000 \u0000 \u0000 \u0000 We systematically searched PubMed, Embase, Scopus in June 2023 to find the relevant articles based on the Preferred Reporting Items for Systematic Review and Meta-analysis statement. All randomized controlled trials (RCTs), observational, and case control studies in English with 10 or more subjects and a minimum of 1 month follow-up after PRP treatment reporting International Index of Erectile Function-Erectile Function (IIEF-EF) score were included. Pooled analysis on outcomes that were reported in at least 2 studies were performed using RevMan 5.4 and STATA18 with 95% confidence intervals (CIs). We also conduct heterogeneity test and a leave-one-out sensitivity analysis.\u0000 \u0000 \u0000 \u0000 A total of three RCTs, three observational studies and one case-control study, comprising 236 patients, were included from 183 studies identified. The pooled analysis showed that PRP injection significantly increased the IIEF-EF score by 3.87 (95% CI: 2.92, 4.83, p<0.00001), 3.01 (95% CI: 2.27, 3.74, p<0.0001), 3.29 (95% CI: 2.26, 4.32, p<0.00001), at 1, 3, and 6, months follow-up. Subgroup analysis of IIEF-EF based on the use of PDE5i in the protocol or during follow-up period also found the same finding result. The proportion of patient who met MCID after 6 months of follow of was 70% (95% CI: 59%, 80%). In term of penile hemodynamic, a significant improvement was found in peak systolic velocity and end diastolic velocity at the end-point of follow-up. On contrary, there was no significant improvement were found for IIEF score of intercourse satisfaction and overall satisfaction domain. The most common complication reported were transient subcutaneous bruising. Two cases reported a formation of painless plaque but no other major adverse events were reported. Consistent result was found after a leave-one-out sensitivity analysis.\u0000 \u0000 \u0000 \u0000 PRP is a promising restorative modality for ED with improvement in IIEF-EF score and penile hemodynamic. However, further studies and human trials are required to confirm the efficacy and durability of this novel treatment as well as to find out the best protocol of administration.\u0000 \u0000 \u0000 \u0000 No.\u0000","PeriodicalId":377411,"journal":{"name":"The Journal of Sexual Medicine","volume":"28 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140269169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-01DOI: 10.1093/jsxmed/qdae002.081
B. T. Aujo, N. Nakasujja, A. Turiho, J. L. Gumikiriza, O. Kakaire
Sexual dysfunction is very distressing to women of reproductive age. Hormonal contraceptives (HC) are often reported to be highly associated with sexual dysfunction. The occurrence of female sexual dysfunction (FSD) varies across African regions however, the literature is scanty. This study, therefore aimed to assess the psychological distress (PD) and coping mechanisms of women with sexual dysfunction using hormonal contraceptives at Kawempe Hospital (KH). To determine the prevalence of psychological distress among women with sexual dysfunction using hormonal contraceptives at Kawempe Hospital To examine the factors associated with psychological distress among women with sexual dysfunction using hormonal contraceptives at Kawempe Hospital To evaluate the coping mechanisms of women with sexual dysfunction using hormonal contraceptives at Kawempe Hospital The study was cross-sectional and conducted by a female team at the family planning clinic of KH. Participants were sexually active females aged 18 to 50 years, who had used HCs for at least six months, and had a positive FSD score below 26.55 on the female sexual function index. PD was assessed using the Kessler Psychological Distress Scale K-6, with a score over 13 indicating PD. Coping mechanisms were determined using the SexFlex scale. The data was analyzed using proportions, means, chi-squares and logistic regression to determine characteristics associated with PD at a significance level of 0.05. Of the 401 individuals screened, 288 who had positive FSD scores were enrolled. The average age of the participants was 28.8 years, and 46.18% used implants for contraception. The prevalence of PD was 55.56%, with 28.47% using reflexive-only coping mechanisms, 24.35% using approach-only mechanisms, 13.19% using both, and 63.19% using neither. Being married (AOR=0.45) and breastfeeding (AOR=0.41) were negatively associated with PD, while using injectables (AOR=7.43), implants (AOR=5.17), levonorgestrel IUD (AOR=4.17), having relationship dissatisfaction (AOR=4.65), and sexual pain (AOR=2.60) were positively associated with PD. PD was prevalent among women with FSD using HCs at Kawempe Hospital and associated with modifiable characteristics. It is recommended that health workers regularly screen for PD among women with FSD using HCs and provide education on malleable characteristics, such as breastfeeding and relationship satisfaction. No.
{"title":"(089) Psychological Distress and Coping Mechanisms among Women with Sexual Dysfunction Using Hormonal Contraceptives at Kawempe Hospital - A Cross-sectional Study","authors":"B. T. Aujo, N. Nakasujja, A. Turiho, J. L. Gumikiriza, O. Kakaire","doi":"10.1093/jsxmed/qdae002.081","DOIUrl":"https://doi.org/10.1093/jsxmed/qdae002.081","url":null,"abstract":"\u0000 \u0000 \u0000 Sexual dysfunction is very distressing to women of reproductive age. Hormonal contraceptives (HC) are often reported to be highly associated with sexual dysfunction. The occurrence of female sexual dysfunction (FSD) varies across African regions however, the literature is scanty. This study, therefore aimed to assess the psychological distress (PD) and coping mechanisms of women with sexual dysfunction using hormonal contraceptives at Kawempe Hospital (KH).\u0000 \u0000 \u0000 \u0000 To determine the prevalence of psychological distress among women with sexual dysfunction using hormonal contraceptives at Kawempe Hospital To examine the factors associated with psychological distress among women with sexual dysfunction using hormonal contraceptives at Kawempe Hospital To evaluate the coping mechanisms of women with sexual dysfunction using hormonal contraceptives at Kawempe Hospital\u0000 \u0000 \u0000 \u0000 The study was cross-sectional and conducted by a female team at the family planning clinic of KH. Participants were sexually active females aged 18 to 50 years, who had used HCs for at least six months, and had a positive FSD score below 26.55 on the female sexual function index. PD was assessed using the Kessler Psychological Distress Scale K-6, with a score over 13 indicating PD. Coping mechanisms were determined using the SexFlex scale. The data was analyzed using proportions, means, chi-squares and logistic regression to determine characteristics associated with PD at a significance level of 0.05.\u0000 \u0000 \u0000 \u0000 Of the 401 individuals screened, 288 who had positive FSD scores were enrolled. The average age of the participants was 28.8 years, and 46.18% used implants for contraception. The prevalence of PD was 55.56%, with 28.47% using reflexive-only coping mechanisms, 24.35% using approach-only mechanisms, 13.19% using both, and 63.19% using neither. Being married (AOR=0.45) and breastfeeding (AOR=0.41) were negatively associated with PD, while using injectables (AOR=7.43), implants (AOR=5.17), levonorgestrel IUD (AOR=4.17), having relationship dissatisfaction (AOR=4.65), and sexual pain (AOR=2.60) were positively associated with PD.\u0000 \u0000 \u0000 \u0000 PD was prevalent among women with FSD using HCs at Kawempe Hospital and associated with modifiable characteristics. It is recommended that health workers regularly screen for PD among women with FSD using HCs and provide education on malleable characteristics, such as breastfeeding and relationship satisfaction.\u0000 \u0000 \u0000 \u0000 No.\u0000","PeriodicalId":377411,"journal":{"name":"The Journal of Sexual Medicine","volume":"24 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140270585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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