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The Role of Stress in Recurrent Aphthous Stomatitis 应激在复发性口腔炎中的作用
Q4 Dentistry Pub Date : 2023-01-01 DOI: 10.1055/s-0043-1768062
N. Nurdiana, P. Ritonga, Pitu Wulandari
Abstract Objectives  This study aimed to determine the role of stress in recurrent aphthous stomatitis. Stress was examined with the Perceived Stress Scale and cortisol levels; meanwhile, recurrent aphthous stomatitis was assessed with the duration of the lesion. Materials and Methods  This was a cross-sectional analytical study conducted at Oral Medicine Installation, Universitas Sumatera Utara Dental Hospital, and Prodia Laboratory, Medan. The subjects were 50 patients with minor recurrent aphthous stomatitis, without systemic disease, who did not take systemic drugs or use orthodontic appliances. The diagnosis of recurrent aphthous stomatitis was established with anamnesis and clinical examination. Stress was examined by filling out the Perceived Stress Scale questionnaire and blood tests for serum cortisol levels. Statistical analysis  The data were analyzed using the Fisher test and Mann–Whitney U test. Results  This study showed no significant relationship between the Perceived Stress Scale category and recurrent aphthous stomatitis, with a p -value of 0.392. This study also showed no significant relationship between blood cortisol level and recurrent aphthous stomatitis with a p -value of 1.000. Conclusion  Stress may play an important role in recurrent aphthous stomatitis. However, this study did not show any difference in stress examined through the Perceived Stress Scale and cortisol levels based on the duration of recurrent aphthous stomatitis.
目的探讨应激在复发性口腔炎中的作用。用感知压力量表和皮质醇水平检测压力;同时,复发性口疮性口炎的评估与病变的持续时间。材料和方法本研究是在苏门答腊北方大学牙科医院口腔医学装置和棉兰Prodia实验室进行的一项横断面分析研究。研究对象为50例轻度复发性口腔炎患者,无全身性疾病,未服用全身性药物或使用正畸矫治器。通过记忆和临床检查确定复发性口疮性口炎的诊断。通过填写感知压力量表问卷和血清皮质醇水平的血液测试来检查压力。统计分析采用Fisher检验和Mann-Whitney U检验。结果感知压力量表类别与复发性口腔炎无显著相关,p值为0.392。本研究也显示血皮质醇水平与复发性口腔炎无显著关系,p值为1.000。结论应激可能在复发性口腔炎中起重要作用。然而,本研究并未显示通过感知压力量表和基于复发性口腔炎持续时间的皮质醇水平检查的压力有任何差异。
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引用次数: 0
Comparison of Mineral Trioxide Aggregate and Biodentine for Open Apex Management in Children with Nonvital Immature Permanent Teeth: A Systematic Review 矿物三氧化物聚集体和生物牙本质在儿童非生命性未成熟恒牙开放性根尖管理中的比较:系统评价
Q4 Dentistry Pub Date : 2022-09-29 DOI: 10.1055/s-0042-1750090
V. Ravindran, G. Jeevanandan, Madhulaxmi Marimuthu, Suman Panda, Ather Ahmed Syed, S. Vishwanathaiah, S. Khanagar, Prabhadevi C. Maganur
Tricalcium silicate cements have long been used in dentistry for management of open apex. Biodentine was introduced to overcome the disadvantages of mineral trioxide aggregate (MTA). The aim of this systematic review was to compare the success rates of biodentine and MTA as a material of choice for the management of open apex in children with nonvital immature permanent teeth. PubMed/Medline, Scopus, EMBASE, Cochrane, and Google Scholar were searched until November 30, 2021, with the search terms young permanent teeth, immature permanent teeth, open apex, MTA, and biodentine. Based on the inclusion criteria, the articles were selected following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and assessed for quality using a risk-of-bias assessment tool. The outcomes of the studies were qualitatively synthesized. A total of 379 studies were identified and after refinement only two studies met the eligibility criteria. Both the studies were performed in children with nonvital pulp status. One of the studies showed a clinical success of 91.66% for MTA and 100% for biodentine in revascularization cases while the other study showed 100% for both the materials in apexification cases. Radiographic success was 100% for both the materials at the end of the follow-up period in both the studies. Treatment modality can create heterogeneity that does not allow making a pooled conclusion for the two materials collectively, which is the case in this review where one study used revascularization, while the other used apexification. An overall high risk of bias was noticed for the selected studies. With high risk of bias and low quality of evidence, a strong definitive conclusion cannot be arrived at. Further studies with proper randomization and minimal risk of bias are required to provide a conclusive result. However, as per the included studies, biodentine can be a material of choice for revascularization while both MTA and biodentine can be used for apexification procedures.
硅酸三钙胶结剂长期应用于牙科治疗开尖。为了克服矿物三氧化物骨料(MTA)的缺点,引入了生物钛矿。本系统综述的目的是比较生物牙定和MTA作为治疗儿童非生命未成熟恒牙开尖的选择材料的成功率。PubMed/Medline、Scopus、EMBASE、Cochrane和谷歌Scholar检索到2021年11月30日,检索词为young恒牙、immature恒牙、open apex、MTA和biodentine。根据纳入标准,按照系统评价和荟萃分析指南的首选报告项目选择文章,并使用偏倚风险评估工具评估质量。对研究结果进行定性综合。共有379项研究被确定,经过改进后,只有两项研究符合资格标准。这两项研究都是在无牙髓状态的儿童中进行的。其中一项研究显示MTA在血运重建术中的临床成功率为91.66%,生物牙定在血运重建术中的临床成功率为100%,而另一项研究显示两种材料在根尖手术中的临床成功率均为100%。在两项研究的随访期结束时,两种材料的放射照相成功率均为100%。治疗方式可能产生异质性,无法对两种材料共同得出汇总结论,在本综述中,一项研究使用血运重建术,而另一项研究使用根尖化。在所选研究中发现总体偏倚风险较高。由于偏倚风险高,证据质量低,因此无法得出强有力的明确结论。进一步的研究需要适当的随机化和最小的偏倚风险来提供一个结论性的结果。然而,根据纳入的研究,生物牙牙定可以作为血运重建的选择材料,而MTA和生物牙牙定都可以用于根尖手术。
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引用次数: 2
Bruxism as a Consequence of Stress and Movement Disorders: Brief Review 磨牙症是压力和运动障碍的结果:简要回顾
Q4 Dentistry Pub Date : 2022-09-05 DOI: 10.1055/s-0042-1754374
A. Heboyan, M. Karobari, Abdullah Hamed Alwadaani, Anand Marya, Muhammad Sohail Zafar
Bruxism is considered to be an unusual repetitive movement syndrome, which is described as involuntary gnashing of teeth. The condition is classified as sleep bruxism (SB) and awake bruxism (AB). The objective of the study was to review the current literature on bruxism and its potential relation to stress and movement disorders. Factors causing bruxism are numerous. It has been found that people suffering from stress are more prone to the condition than healthy subjects. Awake bruxism is frequently observed in subjects with hyperkinetic movement disorders and it can be associated with anxiety, which involves the limbic part of the basal ganglia. However, further studies should be conducted to interpret the link more thoroughly.
磨牙症被认为是一种不寻常的重复运动综合征,被描述为不自主地咬牙切齿。这种情况分为睡眠性磨牙症(SB)和清醒性磨牙病(AB)。本研究的目的是回顾目前关于磨牙症及其与压力和运动障碍的潜在关系的文献。引起磨牙症的因素很多。研究发现,承受压力的人比健康人更容易出现这种情况。清醒磨牙症经常在运动障碍患者中观察到,它可能与焦虑有关,焦虑涉及基底神经节的边缘部分。然而,应该进行进一步的研究,以更彻底地解释这种联系。
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引用次数: 2
Role of Dietary Flavonoids in Preventing COVID-19 Infection and Other Infectious Diseases: A Mini Review 膳食黄酮类化合物在预防COVID-19感染和其他传染病中的作用:综述
Q4 Dentistry Pub Date : 2022-09-01 DOI: 10.1055/s-0042-1760102
Upasana Kumar, Roshan Zoha, Murali Venkata Rama Mohan Kodali, Komal Smriti, Vathsala Patil, Srikanth Gadicherla, Anupam Singh
Abstract Flavonoids are a large group of naturally occurring polyphenolic compounds that are almost universally present in various plant parts such as fruits, berries, leaves, and tubers. These compounds are synthesized in plants in reaction to environmental stressors such as microbial infections. The antioxidant properties in these flavonoids provide us with numerous health benefits. They can be extracted from said natural sources via methods such as maceration and boiling all the way to advanced methods such as microwaves and ultrasounds. Numerous studies have been conducted to research the protective role that flavonoids can play in preventing infectious diseases in humans. The present modalities of treating such infectious diseases rely solely on chemotherapeutic agents and adjunctive therapies such as palliative and supportive care. These chemotherapeutic agents, primarily antibiotics, cause a degeneration of our immunity and an increased susceptibly to several other diseases. Thus, it is crucial that our methods in dealing with infections focus on prevention. This can be achieved by strengthening our immune system, which is the primary line of defense against such diseases. Flavonoids can help boost our immunity, fight infections, and decrease the incidence of antibiotic resistance. Hence, these natural compounds are being largely studied and used as nutraceuticals to supplement our daily diet and successfully reduce the occurrence of major infectious diseases in our body.
摘要黄酮类化合物是一大类天然存在的多酚类化合物,几乎普遍存在于各种植物部位,如水果、浆果、叶子和块茎中。这些化合物是在植物中合成的,以应对环境压力,如微生物感染。这些黄酮类化合物的抗氧化特性为我们提供了许多健康益处。它们可以通过浸渍和煮沸等方法从上述天然来源中提取,一直到微波和超声波等先进方法。已经进行了大量的研究来研究黄酮类化合物在预防人类传染病中的保护作用。目前治疗此类传染病的方式仅依赖于化疗药物和辅助疗法,如姑息治疗和支持性护理。这些化疗药物,主要是抗生素,会导致我们的免疫力下降,并增加对其他几种疾病的易感性。因此,至关重要的是,我们处理感染的方法应侧重于预防。这可以通过加强我们的免疫系统来实现,而免疫系统是抵御此类疾病的主要防线。黄酮类化合物可以帮助提高我们的免疫力,对抗感染,并降低抗生素耐药性的发生率。因此,这些天然化合物正在被大量研究并用作营养品,以补充我们的日常饮食,并成功地减少我们身体中主要传染病的发生。
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引用次数: 0
The Heath of The Peri-Implant Phenotype after Immediate Insertion and Loading of One-Piece and Two-Piece Dental Implants in the Anterior Region. A Clinical and Cone-Beam Computed Tomographic Study 一件式和两件式牙种植体在前牙区即刻插入和加载后种植体周围表型的健康状况。临床和锥束计算机断层扫描研究
Q4 Dentistry Pub Date : 2022-09-01 DOI: 10.1055/s-0042-1760207
M. Assadawy, Ahamed Osama Rifaie
Abstract Objective  This study aimed to provide an inclusive comparison between the peri-implant phenotype of immediately placed in fresh extraction socket one-piece and two-piece implants with immediate loading in the anterior region. Materials and Methods  Twenty-two patients with a mean age of 36 ± 4.6 (4 males and 18 females)) were randomly allocated to the one-piece and the two-piece groups. Each patient had one immediate implant placement with immediate loading by provisional restorations. Gingival Index, Peri-implant Probing depth, Papilla Presence Index, and, Implant Quality Score were recorded at 3, 6, 9 months, and 18 months. Cone beam computerized tomography is utilized to assess peri-implant bone for 1 year. Statistical analysis  A two-sample t -test was used to compare the two groups. Results  Both groups showed similar clinical presentations. For group two, Gingival Index, Papilla Presence Index, Peri-implant Index, Implant Quality Score, and eri-implant bone level showed statistically significant improvement. Group one showed a non-significant increase in bone density. Conclusions  The peri-implant phenotype showed more predictable treatment outcomes in the context of health and esthetics in two-pieces than in one-piece.
抽象目标 本研究旨在对直接放置在新鲜拔出套筒内的一体式和前部立即加载的两件式种植体的种植体周围表型进行包容性比较。材料和方法 22名患者,平均年龄36岁 ± 4.6(4名男性和18名女性)被随机分配到单件组和两件组。每个患者都有一个立即植入的位置,并通过临时修复立即加载。在3个月、6个月、9个月和18个月时记录牙龈指数、种植体周围探测深度、乳头存在指数和种植体质量评分。锥束计算机断层扫描用于评估种植体周围骨骼1年。统计分析 采用双样本t检验对两组患者进行比较。后果 两组患者的临床表现相似。对于第二组,牙龈指数、乳头存在指数、种植体周围指数、种植质量评分和eri种植体骨水平显示出统计学上显著的改善。第一组的骨密度没有显著增加。结论 种植体周围表型在健康和美学方面显示出比单件更可预测的治疗结果。
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引用次数: 0
Assessment of Knowledge and Self-Awareness about Temporomandibular Joint Disorders among Dental Students 口腔专业学生颞下颌关节疾病知识和自我意识评估
Q4 Dentistry Pub Date : 2022-09-01 DOI: 10.1055/s-0042-1759750
M. Najmuddin, A. Shabi, Amna M. Alqadi, Reema Moafa, Safeena Abdul Khader Saheb, Maisah A. Attafi, Fatimah B. Khormi, A. Alqadi, Haifa F. Bokamani, Abdullah J. Hakami
Abstract Objectives This Study Aimed To Find The Relationship Between Lack Of Knowledge And Self-Awareness About Temporomandibular Disorders (Tmds) And Their Signs And Symptoms Among Dental Students Of College Of Dentistry, Jazan University, Jazan, KSA. Materials and Methods  A self-administered structured questionnaire was used to assess the demographic variables, information regarding self-awareness and knowledge about TMDs among dental students. The data obtained were subjected to statistical analysis using the IBM SPSS version 20.0 software. Statistical Analysis  The data obtained were subjected to statistical analysis using the IBM SPSS version 20.0 software. Descriptive statistics, that is, frequencies and percentages were computed. The comparative analysis was done using Chi-square statistical analysis. Results  Out of 406 participants, 44.08% were male and 55.91% were female. Also, 329 were undergraduate students and 77 were interns. Almost a similar percentage of undergraduates and interns were suffering with trismus, articular sounds, pain, and arthralgia. Interns had more incidence of injuries of the head and neck, and had undergone orthodontic treatment, with a significant difference statistically ( p  < 0.05). A significant relation ( p  < 0.05) was observed between responses, with interns having better knowledge regarding investigations and treatment interventions. Conclusion  A direct relationship exists between the level of knowledge about temporomandibular joint (TMJ) and TMDs and self-awareness of its signs and symptoms. A thorough knowledge is required among the students to investigate, diagnose, and treat TMDs at early stages.
摘要目的本研究旨在了解堪萨斯州贾赞市贾赞大学牙科学院牙科学生对颞下颌关节紊乱及其体征和症状缺乏知识和自我意识之间的关系。材料和方法 使用自行管理的结构化问卷来评估牙科学生的人口统计学变量、自我意识信息和TMDs知识。使用IBM SPSS 20.0版软件对获得的数据进行统计分析。统计分析 使用IBM SPSS 20.0版软件对获得的数据进行统计分析。描述性统计,即计算频率和百分比。比较分析采用卡方统计分析。后果 在406名参与者中,44.08%为男性,55.91%为女性。此外,329人为本科生,77人为实习生。几乎有相似比例的本科生和实习生患有牙痛、关节音、疼痛和关节痛。实习生的头颈部损伤发生率较高,并接受过正畸治疗,差异有统计学意义(p < 0.05) < 0.05),实习生对调查和治疗干预有更好的了解。结论 颞下颌关节(TMJ)和TMDs的知识水平与对其体征和症状的自我意识之间存在直接关系。学生需要掌握全面的知识,以便在早期阶段调查、诊断和治疗TMDs。
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引用次数: 0
Evaluation of the Masking Effect of Different Glass Ionomer Restorations following Silver Diamine fluoride and Potassium Iodide Application: An In Vitro Study 应用氟化二胺银和碘化钾后不同玻璃离子修复体遮蔽效应的评价:体外研究
Q4 Dentistry Pub Date : 2022-09-01 DOI: 10.1055/s-0042-1759753
R. Raafat, Mohamed Abuzaid, R. A. Abd ElAziz
Abstract Objectives  This is an in vitro study that aimed to evaluate the ability of different glass ionomer restorations to mask the discoloration produced following silver diamine fluoride (SDF) only and after potassium iodide (KI) application. Materials and Methods  Thirty-six extracted human adult posterior teeth were collected. Box-shaped cavities (4 × 2 × 2 mm 3 ) were prepared along the cementoenamel junction. Specimens were randomly divided into two major groups according to the materials applied under the restorations group (A) 38% silver diamine fluoride (SDF) followed by immediate application of potassium iodide (KI), group (B) 38% silver diamine fluoride (SDF) only. Each group was further subdivided according to the restorative material applied as follows ( n  = 6): subgroup (I) zirconia reinforced glass ionomer, subgroup (II) resin-modified glass ionomer restoration, and subgroup (III) high viscous glass ionomer restoration. Color assessment of all specimens was performed using a reflective spectrophotometer. Specimens' color was assessed color of normal dentin then assessed immediately after application of SDF (group A) and after application SDF + KI (group B) with the respective restorative material used. Statistical Analysis  Data showed parametric distribution and variance homogeneity and were analyzed using one-way analysis of variance followed by Tukey's post hoc test. Results  Intergroup comparisons showed that for SDF and SDF + KI samples, there was a significant difference between the different restorative materials ( p  < 0.001). For glass ionomer, SDF samples had significantly higher color change value than SDF + KI ( p  < 0.001), while for RMGI and zirconia reinforced glass ionomer, SDF + KI samples had significantly higher value ( p  < 0.001) although zirconia reinforced glass ionomer showed the least color change following SDF (6.00 ± 2.74). Conclusion  Within the limitations of this study, we could conclude that using zirconia reinforced glass ionomer could have a good masking effect on discoloration produced by SDF. While the resin-modified glass ionomer restoration showed more discoloration and darkening effect even after using of KI. Also, using KI in combination with SDF had a good masking effect on discoloration that produced by SDF.
抽象目标 这是一项体外研究,旨在评估不同玻璃离聚物修复体掩盖仅在氟化二胺银(SDF)和应用碘化钾(KI)后产生的变色的能力。材料和方法 采集了36颗已拔除的成人后牙。箱形空腔(4 × 2. × 2. mm3)。根据修复体下使用的材料,将标本随机分为两大组:(A)38%氟化二胺银(SDF),然后立即使用碘化钾(KI);(B)仅使用38%氟化二酰胺银(SDF。根据使用的修复材料,每组进一步细分如下(n = 6) :亚组(I)氧化锆增强玻璃离聚物,亚组(II)树脂改性玻璃离聚体修复体,和亚组(III)高粘性玻璃离聚剂修复体。使用反射式分光光度计对所有样品进行颜色评估。样品的颜色评估为正常牙本质的颜色,然后在施用SDF后立即评估(A组)和施用SDF后 + KI(B组),并使用相应的修复材料。统计分析 数据显示了参数分布和方差同质性,并使用单向方差分析和Tukey的事后检验进行分析。后果 组间比较显示,对于SDF和SDF + KI样品,不同修复材料之间有显著差异(p < 0.001)。对于玻璃离聚物,SDF样品的颜色变化值明显高于SDF + KI(p < 0.001),而对于RMGI和氧化锆增强玻璃离聚物,SDF + KI样本具有显著更高的值(p < 0.001),尽管氧化锆增强玻璃离聚物在SDF之后显示出最小的颜色变化(6.00 ± 2.74).结论 在本研究的限制范围内,我们可以得出结论,使用氧化锆增强玻璃离聚物可以对SDF产生的变色具有良好的掩蔽效果。树脂改性的玻璃离聚物修复体即使在使用KI后也表现出更多的变色和变暗效果。KI与SDF联合使用对SDF产生的变色有很好的掩蔽作用。
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引用次数: 0
A Comparative Evaluation of Malocclusion and Associated Risk Factors in Patients Suffering with Temporomandibular Disorders: A Systematic Review and Meta-analysis of Observational Studies 颞下颌疾病患者错颌和相关危险因素的比较评价:观察性研究的系统回顾和荟萃分析
Q4 Dentistry Pub Date : 2022-09-01 DOI: 10.1055/s-0042-1759754
Anshul Trivedi, S. Agarwal, I. Gupta, Roma Goswami, Apoorva Mowar
Abstract An association of malocclusion as potent risk factor to temporomandibular disorders (TMDs) has been under question since ages. A systematic review and meta-analysis of case–control and cohort studies was performed following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses)guidelines to compare the prevalence of TMDs in subjects with malocclusion to patients with normocclusion. The study was registered on the PROSPERO database (identifier: CRD42022315863). An elaborate electronic database (PubMed, DOAJ, and Google Scholar) and manual search resulted in 325 articles, among which 7 and 3 articles were shortlisted for qualitative and quantitative review, respectively, for articles published from January 2000 until December 2021. A total of 4,183 participants were included in this review with age range of 5 to 75 years. New–Castle Ottawa tool was employed for quality assessment, while I 2 statistical value for meta-analysis was interpreted in accordance with the Cochrane Handbook for Systematic Reviews of Interventions. Fixed effect model was applied as, I 2  = 0. Pooled odds ratio with 95% confidence interval for all three studies was 14.64 [4.43, 48.36] suggesting that TMDs were 14.64 times more associated in patients with malocclusion (cases) than patients without malocclusion (controls). Within the limitations and fair quality of evidence of the current review and analysis, TMDs and associated symptoms are more prevalent in patients with malocclusion with or without more associated factors.
摘要:牙合错作为颞下颌疾病(TMDs)的潜在危险因素的相关性一直受到质疑。遵循PRISMA(系统评价和荟萃分析的首选报告项目)指南,对病例对照和队列研究进行了系统评价和荟萃分析,以比较错颌合患者和正常颌合患者的tmd患病率。该研究已在PROSPERO数据库中注册(标识符:CRD42022315863)。通过精心设计的电子数据库(PubMed、DOAJ和谷歌Scholar)和人工检索,共检索到325篇文章,其中2000年1月至2021年12月发表的文章分别有7篇和3篇入选定性和定量评审。这项综述共纳入了4183名参与者,年龄范围从5岁到75岁。质量评价采用New-Castle Ottawa工具,meta分析采用Cochrane Handbook for Systematic Reviews of Interventions进行解释。采用固定效应模型,i2 = 0。三项研究的合并优势比(95%可信区间)为14.64[4.43,48.36],表明错颌合患者(病例)与无错颌合患者(对照)的TMDs相关性为14.64倍。在目前综述和分析的证据的局限性和公平质量范围内,TMDs和相关症状在有或没有更多相关因素的错颌合患者中更为普遍。
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引用次数: 1
Quantification of Porphyromonas gingivalis Bacteria in Final Trimester of Pregnant Women According to Their Oral Health Status 根据孕妇口腔健康状况对妊娠晚期牙龈卟啉单胞菌的定量检测
Q4 Dentistry Pub Date : 2022-09-01 DOI: 10.1055/s-0042-1759755
R. I. Roestamadji, U. Tedjosasongko, Nuraini Indrastie, I. Diyatri, M. Surboyo, S. Sudarmo, Budi Santoso, N. Takahashi
Abstract Objective  Pregnant women are more at risk to suffer dental infection. Untreated dental infection during pregnancy can lead to more serious problems to mothers and their children, such as premature birth and low birth weight. This study aims to analyzed the relationship between oral hygiene status (OHI-S) and the expression of Porphyromonas gingivalis in third trimester pregnant women. Materials and Methods  This was an observational analytic study with a cross-sectional study design. Patients consisted of 37 final trimester pregnant women, divided into good OHI-S and fair OHI-S. The P. gingivalis expression was measured using real-time qPCR from the mucosal swab. Results  The P. gingivalis expression found no differences between good OHI-s and fair OHI-S ( p  = 0.557). Conclusion  Based on this study, although there was no significant difference in P. gingivalis expression in the final trimester based on their oral health status, oral health is considered important to be taken care of during pregnancy.
抽象目标 孕妇患牙齿感染的风险更大。怀孕期间未经治疗的牙齿感染会给母亲及其子女带来更严重的问题,如早产和低出生体重。本研究旨在分析妊娠晚期孕妇口腔卫生状况(OHI-S)与牙龈卟啉单胞菌表达之间的关系。材料和方法 这是一项采用横断面研究设计的观察性分析研究。患者包括37名妊娠晚期孕妇,分为良好OHI-S和一般OHI-S。使用来自粘膜拭子的实时qPCR测量牙龈卟啉单胞菌的表达。后果 牙龈卟啉单胞菌的表达在良好的OHI-s和正常的OHI-s之间没有差异(P = 0.557)。结论 根据这项研究,尽管根据口腔健康状况,牙龈卟啉单胞菌在妊娠晚期的表达没有显著差异,但口腔健康被认为是妊娠期间需要注意的重要问题。
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引用次数: 0
Polymorphic Variants across Population of the Growth Hormone Receptor with Mandible Prognathism: A Systematic Review 生长激素受体与下颌骨前突症的多态变异:一项系统综述
Q4 Dentistry Pub Date : 2022-09-01 DOI: 10.1055/s-0042-1759752
S. Sadputranto, A. Maskoen, A. Laviana, E. Sjamsudin
Abstract Genetic influences are critical for determining mandibular protrusion in class IIImalocclusion cases, and growth hormone receptors (GHRs) are thought to have an essential impact on craniofacial bone growth. This review aimed to assess the association between GHR gene polymorphism variants and mandibular morphology. Studies were extensively searched using PubMed and Google Scholar until December 2020. The study design according to PECOS was: P, class III malocclusion; E, GHR polymorphism; no polymorphism in C, GHR; O, linear dimensional changes in maxillary and mandibular measurements; and S, cross-sectional and case-control studies. Selected studies were of acceptable methodological quality on a 10-point scale. A preliminary search identified 107 studies; after excluding duplicate abstracts, 63 studies were screened. Nine studies were subsequently included in the systematic review. Conclusion Polymorphic variants at rs6180, rs6182, and rs6184 in the GHR gene were associated with condylion-gonion measures in Asians and Turks but not in Colombians and Egyptians.
摘要基因影响对确定III类错牙合病例的下颌前突至关重要,生长激素受体(GHRs)被认为对颅面骨生长有重要影响。本综述旨在评估GHR基因多态性变异与下颌形态之间的关系。在2020年12月之前,使用PubMed和Google Scholar对研究进行了广泛搜索。根据PECOS的研究设计为:P,III类错牙合;E、 GHR多态性;C、GHR无多态性;O、 上颌和下颌测量的线性尺寸变化;和S,横断面和病例对照研究。选定的研究在10分制上具有可接受的方法学质量。初步搜索确定了107项研究;排除重复摘要后,筛选出63项研究。9项研究随后被纳入系统综述。结论GHR基因rs6180、rs6182和rs6184多态性变异与亚洲人和土耳其人的髁突角测量有关,但与哥伦比亚人和埃及人无关。
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European Journal of General Dentistry
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