Pub Date : 2025-12-10DOI: 10.1016/j.abrep.2025.100649
Sojung Youn, Brian A. Anderson
Background
Abnormal attentional biases for tobacco cues have been observed in the dot-probe task. With a recent increase in electronic nicotine delivery systems (ENDS) use, researchers have investigated the effect of ENDS use on early and later stages of attentional bias. Studies have provided support for later-stage attentional biases among ENDS users but not an orienting bias, which may be difficult to detect with smaller sample sizes, and due to low reliability. The present study tested orienting bias among young adult ENDS users and nonusers to ENDS-related images using a modified dot-probe task.
Method
A total of 224 participants were assigned to an ENDS user group (n = 110) or a control group (n = 114) following their history of ENDS use. A modified version of the dot-probe task was used where a rotated target letter (“T”) appeared shortly after image (ENDS-related and neutral) offset, requiring a directional response.
Results
The ENDS group exhibited a significantly larger ENDS-related orienting bias compared to the control group in response time and accuracy. A habituation effect was also observed, with the ENDS-related attentional bias being restricted for the first epoch of trials. Consistent with previous studies, the ENDS-related attentional bias exhibited low internal reliability.
Conclusions
A significant but short-lived orienting bias towards ENDS-related cues in ENDS users was observed. Similar to other substances of abuse, ENDS use affects early-stage attentional processes. Our findings also suggest ways to more robustly measure such early-stage attentional biases in ENDS users.
{"title":"Orienting bias towards electronic nicotine delivery system (ENDS) cues","authors":"Sojung Youn, Brian A. Anderson","doi":"10.1016/j.abrep.2025.100649","DOIUrl":"10.1016/j.abrep.2025.100649","url":null,"abstract":"<div><h3>Background</h3><div>Abnormal attentional biases for tobacco cues have been observed in the dot-probe task. With a recent increase in electronic nicotine delivery systems (ENDS) use, researchers have investigated the effect of ENDS use on early and later stages of attentional bias. Studies have provided support for later-stage attentional biases among ENDS users but not an orienting bias, which may be difficult to detect with smaller sample sizes, and due to low reliability. The present study tested orienting bias among young adult ENDS users and nonusers to ENDS-related images using a modified dot-probe task.</div></div><div><h3>Method</h3><div>A total of 224 participants were assigned to an ENDS user group (<em>n</em> = 110) or a control group (<em>n</em> = 114) following their history of ENDS use. A modified version of the dot-probe task was used where a rotated target letter (“T”) appeared shortly after image (ENDS-related and neutral) offset, requiring a directional response.</div></div><div><h3>Results</h3><div>The ENDS group exhibited a significantly larger ENDS-related orienting bias compared to the control group in response time and accuracy. A habituation effect was also observed, with the ENDS-related attentional bias being restricted for the first epoch of trials. Consistent with previous studies, the ENDS-related attentional bias exhibited low internal reliability.</div></div><div><h3>Conclusions</h3><div>A significant but short-lived orienting bias towards ENDS-related cues in ENDS users was observed. Similar to other substances of abuse, ENDS use affects early-stage attentional processes. Our findings also suggest ways to more robustly measure such early-stage attentional biases in ENDS users.</div></div>","PeriodicalId":38040,"journal":{"name":"Addictive Behaviors Reports","volume":"23 ","pages":"Article 100649"},"PeriodicalIF":2.8,"publicationDate":"2025-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145737294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01DOI: 10.1016/j.abrep.2025.100642
Anna Westh Stenbro , Thomas Marcussen , David C. Hodgins , Thomas Tandrup Lamm , Lisbeth Frostholm
Background
Despite the availability of effective treatments for Gambling Disorder (GD), help-seeking remains low, and attrition rates are high. Internet-based cognitive behavioral therapy (iCBT) may address barriers to treatment access, but evidence comparing asynchronous iCBT with synchronous CBT (sCBT) is limited.
Objective
This study protocol outlines a non-inferiority randomized controlled trial (RCT) comparing the effectiveness of “SpilleFri” (SF), an asynchronous therapist-guided iCBT program, with individual sCBT delivered in-person or via video for adults with GD.
Methods
A total of 150 patients diagnosed with GD will be randomized to SF or sCBT. The primary outcome is change in GD severity, measured by the National Opinion Research Center DSM Screen for Gambling Problems (NODS), from baseline to three months post-treatment. Secondary outcomes include gambling behavior, psychological distress, relationship quality, and treatment process variables. Data will be collected at eight time points, including a 12-month follow-up. Non-inferiority will be tested using mixed linear models with a predefined margin of −2 NODS points. Process variables and moderators of treatment response will be explored.
Discussion
This trial addresses a critical gap in GD treatment research by directly comparing asynchronous and synchronous CBT formats. If SF proves non-inferior to sCBT, it could offer a scalable, flexible, and resource-efficient alternative for GD treatment. Findings may inform stepped-care models and broaden access to evidence-based interventions.
{"title":"Internet-based versus synchronous cognitive behavioral therapy for gambling disorder: Study protocol for a non-inferiority randomized controlled trial","authors":"Anna Westh Stenbro , Thomas Marcussen , David C. Hodgins , Thomas Tandrup Lamm , Lisbeth Frostholm","doi":"10.1016/j.abrep.2025.100642","DOIUrl":"10.1016/j.abrep.2025.100642","url":null,"abstract":"<div><h3>Background</h3><div>Despite the availability of effective treatments for Gambling Disorder (GD), help-seeking remains low, and attrition rates are high. Internet-based cognitive behavioral therapy (iCBT) may address barriers to treatment access, but evidence comparing asynchronous iCBT with synchronous CBT (sCBT) is limited.</div></div><div><h3>Objective</h3><div>This study protocol outlines a non-inferiority randomized controlled trial (RCT) comparing the effectiveness of “SpilleFri” (SF), an asynchronous therapist-guided iCBT program, with individual sCBT delivered in-person or via video for adults with GD.</div></div><div><h3>Methods</h3><div>A total of 150 patients diagnosed with GD will be randomized to SF or sCBT. The primary outcome is change in GD severity, measured by the National Opinion Research Center DSM Screen for Gambling Problems (NODS), from baseline to three months post-treatment. Secondary outcomes include gambling behavior, psychological distress, relationship quality, and treatment process variables. Data will be collected at eight time points, including a 12-month follow-up. Non-inferiority will be tested using mixed linear models with a predefined margin of −2 NODS points. Process variables and moderators of treatment response will be explored.</div></div><div><h3>Discussion</h3><div>This trial addresses a critical gap in GD treatment research by directly comparing asynchronous and synchronous CBT formats. If SF proves non-inferior to sCBT, it could offer a scalable, flexible, and resource-efficient alternative for GD treatment. Findings may inform stepped-care models and broaden access to evidence-based interventions.</div></div>","PeriodicalId":38040,"journal":{"name":"Addictive Behaviors Reports","volume":"22 ","pages":"Article 100642"},"PeriodicalIF":2.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145614591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-26DOI: 10.1016/j.abrep.2025.100645
Ong George Ngieng , Lucy Albertella , Ty Hayes , Antonio Verdejo-Garcia , Lukasz Walasek , Elliot A. Ludvig , Daniel Bennett
A common feature of contemporary sports-betting apps is ‘instant cash-out’, which allows users to settle a bet early in exchange for a discounted immediate payout. Despite high prevalence and links with gambling-related harm, relatively little is known about how personality traits associated with gambling, such as impulsivity, predict instant cash-out usage. To address this question, we recruited 145 general-population adult participants (69 men, 66 women, 10 non-binary or undisclosed; Mage = 36.3, SD = 10.7; participants resided in Australia, Canada, Ireland, New Zealand, the UK, or the USA) to complete five self-report questionnaires related to impulsivity, as well as the Problem Gambling Severity Index (PGSI), and a validated cognitive task measuring individual differences in cash-out frequency. We then assessed how cash-out frequency in the behavioral task was associated with both self-reported impulsivity and PGSI. We found that cash-out frequency was negatively correlated both with PGSI scores and with a number of impulsivity-related traits including Dysfunctional Impulsivity, Lack of Premeditation, Positive Urgency, Sensation Seeking, and Fun Seeking. An exploratory factor analysis revealed that higher scores on a latent ‘Dysfunctional Impulsivity’ factor were negatively associated with cash-out frequency overall, whereas higher scores on an ‘Inhibition and Inflexibility’ factor predicted higher cash-out frequency specifically for bets with a low win probability. Taken together, results suggest that instant cash-out may primarily appeal to less impulsive people and those with lower PGSI scores. This raises the possibility that instant cash-out may specifically facilitate increased gambling behaviors among people with less prior experience of gambling.
{"title":"Greater impulsivity is associated with a reduced propensity to cash out of bets","authors":"Ong George Ngieng , Lucy Albertella , Ty Hayes , Antonio Verdejo-Garcia , Lukasz Walasek , Elliot A. Ludvig , Daniel Bennett","doi":"10.1016/j.abrep.2025.100645","DOIUrl":"10.1016/j.abrep.2025.100645","url":null,"abstract":"<div><div>A common feature of contemporary sports-betting apps is ‘instant cash-out’, which allows users to settle a bet early in exchange for a discounted immediate payout. Despite high prevalence and links with gambling-related harm, relatively little is known about how personality traits associated with gambling, such as impulsivity, predict instant cash-out usage. To address this question, we recruited 145 general-population adult participants (69 men, 66 women, 10 non-binary or undisclosed; <em>M<sub>age</sub> =</em> 36.3, <em>SD</em> = 10.7; participants resided in Australia, Canada, Ireland, New Zealand, the UK, or the USA) to complete five self-report questionnaires related to impulsivity, as well as the Problem Gambling Severity Index (PGSI), and a validated cognitive task measuring individual differences in cash-out frequency. We then assessed how cash-out frequency in the behavioral task was associated with both self-reported impulsivity and PGSI. We found that cash-out frequency was negatively correlated both with PGSI scores and with a number of impulsivity-related traits including Dysfunctional Impulsivity, Lack of Premeditation, Positive Urgency, Sensation Seeking, and Fun Seeking. An exploratory factor analysis revealed that higher scores on a latent ‘Dysfunctional Impulsivity’ factor were negatively associated with cash-out frequency overall, whereas higher scores on an ‘Inhibition and Inflexibility’ factor predicted higher cash-out frequency specifically for bets with a low win probability. Taken together, results suggest that instant cash-out may primarily appeal to less impulsive people and those with lower PGSI scores. This raises the possibility that instant cash-out may specifically facilitate increased gambling behaviors among people with less prior experience of gambling.</div></div>","PeriodicalId":38040,"journal":{"name":"Addictive Behaviors Reports","volume":"23 ","pages":"Article 100645"},"PeriodicalIF":2.8,"publicationDate":"2025-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145625303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-20DOI: 10.1016/j.abrep.2025.100644
Tarik D. Goulbourne , Nathan Grant Smith , Ezemenari M. Obasi , Lorraine R. Reitzel
Purpose
Bisexual people experience bisexual-specific stressors (e.g., anti-bisexual discrimination, internalized binegativity) that impact health outcomes. Still, little research has explored relationships between bisexual-specific stressors and substance use. Additionally, distress tolerance is negatively associated with substance use in non-sexual-minority samples, but only one study has examined distress tolerance in sexual minorities, and none have examined its relations to substance use in bisexual samples. This study examined the indirect relationship between anti-bisexual discrimination and substance use through internalized binegativity, sexual orientation concealment, and distress tolerance.
Methods
Bisexual adults aged 18–70 (M = 35, N = 97) were recruited locally and nationally, and reported experiences of anti-bisexual discrimination, internalized binegativity, sexual orientation concealment, distress tolerance, and substance use (i.e., 90-day marijuana and cocaine use, 30-day number of daily standard drinks, 30-day binge drinking).
Results
Anti-bisexual discrimination was significantly related to cocaine use indirectly through sexual orientation concealment and directly associated with internalized binegativity and sexual orientation concealment. There were also significant indirect effects for the relationship between anti-bisexual discrimination and cocaine use through internalized binegativity and for the relationship between anti-bisexual discrimination and alcohol use through internalized binegativity. Neither anti-bisexual discrimination nor internalized binegativity, sexual orientation concealment, or distress tolerance were significantly, directly associated with alcohol use, binge drinking, or marijuana use.
Conclusion
As the first study to examine the role of distress tolerance in the relationship between bisexual-specific minority stressors and substance use, the findings provide a novel contribution to the exploration of bisexual-specific health disparities and highlight a need for targeted clinical interventions.
目的双性恋者会经历双性恋特有的压力源(例如,对双性恋的歧视、内化的消极情绪),这些压力源会影响健康结果。然而,很少有研究探索双性恋特定压力源与药物使用之间的关系。此外,在非性少数样本中,痛苦耐受性与物质使用呈负相关,但只有一项研究调查了性少数群体的痛苦耐受性,而没有一项研究调查了双性恋样本中痛苦耐受性与物质使用的关系。本研究通过内化负性、性取向隐瞒性和痛苦耐受性来考察反双性恋歧视与物质使用之间的间接关系。方法招募18-70岁的成年双性恋者(M = 35, N = 97),报告其反双性恋歧视、内化双性恋消极、性取向隐藏性、痛苦耐受力和物质使用(即90天大麻和可卡因使用、30天每日标准饮酒量、30天酗酒)经历。结果反双性恋歧视与可卡因使用存在间接性取向隐瞒相关,与内化消极性和性取向隐瞒直接相关。反双性恋歧视与可卡因使用之间的关系通过内化的消极作用,以及反双性恋歧视与酒精使用之间的关系通过内化的消极作用,也存在显著的间接影响。对双性恋的歧视、内化的消极、性取向隐蔽性或痛苦容忍与酒精使用、酗酒或大麻使用都没有显著的直接关系。结论该研究首次探讨了双性恋特定少数群体应激源与物质使用之间的关系,为探索双性恋特定健康差异提供了新的贡献,并强调了有针对性的临床干预的必要性。
{"title":"The indirect effects of discrimination on substance use in bisexual adults through internalized binegativity, concealment, and distress tolerance","authors":"Tarik D. Goulbourne , Nathan Grant Smith , Ezemenari M. Obasi , Lorraine R. Reitzel","doi":"10.1016/j.abrep.2025.100644","DOIUrl":"10.1016/j.abrep.2025.100644","url":null,"abstract":"<div><h3>Purpose</h3><div>Bisexual people experience bisexual-specific stressors (e.g., anti-bisexual discrimination, internalized binegativity) that impact health outcomes. Still, little research has explored relationships between bisexual-specific stressors and substance use. Additionally, distress tolerance is negatively associated with substance use in non-sexual-minority samples, but only one study has examined distress tolerance in sexual minorities, and none have examined its relations to substance use in bisexual samples. This study examined the indirect relationship between anti-bisexual discrimination and substance use through internalized binegativity, sexual orientation concealment, and distress tolerance.</div></div><div><h3>Methods</h3><div>Bisexual adults aged 18–70 (M = 35, N = 97) were recruited locally and nationally, and reported experiences of anti-bisexual discrimination, internalized binegativity, sexual orientation concealment, distress tolerance, and substance use (i.e., 90-day marijuana and cocaine use, 30-day number of daily standard drinks, 30-day binge drinking).</div></div><div><h3>Results</h3><div>Anti-bisexual discrimination was significantly related to cocaine use indirectly through sexual orientation concealment and directly associated with internalized binegativity and sexual orientation concealment. There were also significant indirect effects for the relationship between anti-bisexual discrimination and cocaine use through internalized binegativity and for the relationship between anti-bisexual discrimination and alcohol use through internalized binegativity. Neither anti-bisexual discrimination nor internalized binegativity, sexual orientation concealment, or distress tolerance were significantly, directly associated with alcohol use, binge drinking, or marijuana use.</div></div><div><h3>Conclusion</h3><div>As the first study to examine the role of distress tolerance in the relationship between bisexual-specific minority stressors and substance use, the findings provide a novel contribution to the exploration of bisexual-specific health disparities and highlight a need for targeted clinical interventions.</div></div>","PeriodicalId":38040,"journal":{"name":"Addictive Behaviors Reports","volume":"23 ","pages":"Article 100644"},"PeriodicalIF":2.8,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145600656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-14DOI: 10.1016/j.abrep.2025.100643
Josefine Östh , Andreas Lundin , Peter Wennberg , Sven Andréasson , Anna-Karin Danielsson
Aim
Accurately measuring alcohol consumption remains a challenge. This study aimed to evaluate two app-based methods, one using drink-count logging and one using a breathalyzer, by comparing them to retrospective self-report (Timeline Followback, TLFB) and a biomarker of alcohol use (Phosphatidylethanol, PEth).
Methods
Data were acquired from a randomized controlled trial involving alcohol-dependent adults (n = 110). Standard drinks, drinking days, and heavy drinking days reported via the drink-counting app or breathalyzer, were compared with TLFB data over the 12-week period using Lin’s concordance correlation coefficient (CCC). Correlation with PEth was assessed only at the 12-week mark, using Spearman’s rank correlation coefficient (rho) and Receiver Operating Characteristic (ROC) curves, reporting the area under the curve (AUC).
Results
Compared to app-based methods, TLFB consistently identified more drinking days and heavy drinking days. However, the drink-counting app’s estimates were still relatively close to TLFB and demonstrated strong agreement for drinking days across the different time intervals (CCC = 0.71–0.86). The drink-counting app also showed a strong correlation with PEth values for standard drinks and drinking days (rho = 0.74–0.78). In contrast, breathalyzer data generally showed weak agreement with both TLFB and PEth.
Conclusions
Although TLFB yielded more drinking and heavy drinking days, the drink-counting app showed strong agreement with TLFB and correlated closely with PEth levels, indicating good validity. In contrast, breathalyzer data showed weaker agreement, likely due to lower usage during drinking episodes. These findings suggest that drink-counting apps could provide a reliable tool for monitoring alcohol use, offering advantages over both retrospective reports and breathalyzer measures.
{"title":"Evaluating a drink-counting and a breathalyzer-coupled app for monitoring alcohol use: A comparison with timeline followback and peth biomarker","authors":"Josefine Östh , Andreas Lundin , Peter Wennberg , Sven Andréasson , Anna-Karin Danielsson","doi":"10.1016/j.abrep.2025.100643","DOIUrl":"10.1016/j.abrep.2025.100643","url":null,"abstract":"<div><h3>Aim</h3><div>Accurately measuring alcohol consumption remains a challenge. This study aimed to evaluate two app-based methods, one using drink-count logging and one using a breathalyzer, by comparing them to retrospective self-report (Timeline Followback, TLFB) and a biomarker of alcohol use (Phosphatidylethanol, PEth).</div></div><div><h3>Methods</h3><div>Data were acquired from a randomized controlled trial involving alcohol-dependent adults (n = 110). Standard drinks, drinking days, and heavy drinking days reported via the drink-counting app or breathalyzer, were compared with TLFB data over the 12-week period using Lin’s concordance correlation coefficient (CCC). Correlation with PEth was assessed only at the 12-week mark, using Spearman’s rank correlation coefficient (rho) and Receiver Operating Characteristic (ROC) curves, reporting the area under the curve (AUC).</div></div><div><h3>Results</h3><div>Compared to app-based methods, TLFB consistently identified more drinking days and heavy drinking days. However, the drink-counting app’s estimates were still relatively close to TLFB and demonstrated strong agreement for drinking days across the different time intervals (CCC = 0.71–0.86). The drink-counting app also showed a strong correlation with PEth values for standard drinks and drinking days (rho = 0.74–0.78). In contrast, breathalyzer data generally showed weak agreement with both TLFB and PEth.</div></div><div><h3>Conclusions</h3><div>Although TLFB yielded more drinking and heavy drinking days, the drink-counting app showed strong agreement with TLFB and correlated closely with PEth levels, indicating good validity. In contrast, breathalyzer data showed weaker agreement, likely due to lower usage during drinking episodes. These findings suggest that drink-counting apps could provide a reliable tool for monitoring alcohol use, offering advantages over both retrospective reports and breathalyzer measures.</div></div>","PeriodicalId":38040,"journal":{"name":"Addictive Behaviors Reports","volume":"22 ","pages":"Article 100643"},"PeriodicalIF":2.8,"publicationDate":"2025-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145519560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Despite the increasing clinical recognition of internet gaming disorder (IGD), treatment options remain scarce, and relapse rates are high. One major challenge is the pervasive presence of digital triggers that reinforce gaming behaviors, particularly through social media platforms, which are integral to gaming culture. Further research is needed on how gaming-related social media content affects gaming desire and physiological reactions because this topic remains understudied. This study investigated the effects of gaming-related social media videos on gaming desire and skin conductance response (SCR) in individuals with IGD and healthy controls (HCs) who casually play online games. While participants viewed gaming-related and neutral videos from social media, their gaming desire and SCR were assessed. Correlations between SCR and clinical variables were also examined. Notably, both groups exhibited increased gaming desire and SCR after viewing gaming-related videos compared with those after viewing neutral ones. Although self-reported gaming desire was comparable between groups, the SCR was significantly higher in the IGD group. In the HC group, SCR levels were positively correlated with gaming history. The dissociation between subjective and physiological outcomes may indicate implicit sensitization to gaming-related cues in IGD, suggesting that physiological reactivity could occur independently of self-reported cravings. Our findings can help elucidate the underlying mechanisms of IGD and highlight the need for further research on strategies aimed at managing gaming-related cue exposure in digital environments.
{"title":"Psychophysiological response of individuals with internet gaming disorder to gaming content from social media","authors":"Daisuke Jitoku , Nanase Kobayashi , Yuka Fujimoto , Chenyu Qian , Shoko Okuzumi , Shisei Tei , Takehiro Tamura , Hidehiko Takahashi , Takefumi Ueno , Junya Fujino","doi":"10.1016/j.abrep.2025.100641","DOIUrl":"10.1016/j.abrep.2025.100641","url":null,"abstract":"<div><div>Despite the increasing clinical recognition of internet gaming disorder (IGD), treatment options remain scarce, and relapse rates are high. One major challenge is the pervasive presence of digital triggers that reinforce gaming behaviors, particularly through social media platforms, which are integral to gaming culture. Further research is needed on how gaming-related social media content affects gaming desire and physiological reactions because this topic remains understudied. This study investigated the effects of gaming-related social media videos on gaming desire and skin conductance response (SCR) in individuals with IGD and healthy controls (HCs) who casually play online games. While participants viewed gaming-related and neutral videos from social media, their gaming desire and SCR were assessed. Correlations between SCR and clinical variables were also examined. Notably, both groups exhibited increased gaming desire and SCR after viewing gaming-related videos compared with those after viewing neutral ones. Although self-reported gaming desire was comparable between groups, the SCR was significantly higher in the IGD group. In the HC group, SCR levels were positively correlated with gaming history. The dissociation between subjective and physiological outcomes may indicate implicit sensitization to gaming-related cues in IGD, suggesting that physiological reactivity could occur independently of self-reported cravings. Our findings can help elucidate the underlying mechanisms of IGD and highlight the need for further research on strategies aimed at managing gaming-related cue exposure in digital environments.</div></div>","PeriodicalId":38040,"journal":{"name":"Addictive Behaviors Reports","volume":"22 ","pages":"Article 100641"},"PeriodicalIF":2.8,"publicationDate":"2025-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145519535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-01DOI: 10.1016/j.abrep.2025.100640
Jennifer M. Belus , Morgan S. Anvari , Hongjie Ke , Kristen S. Regenauer , Tianzhou Ma , Bronwyn Myers , Lena S. Andersen , John A. Joska , Jessica F. Magidson
Background
Despite documented relationships between multiple forms of stigma and health outcomes, limited research has examined the effects of both HIV and alcohol stigmas on objectively measured alcohol use. Research is needed to better understand relationships between stigma and health outcomes to inform intervention efforts that reduce stigma.
Methods
Participants (N = 60) who met criteria for unhealthy alcohol use and suboptimal HIV medication adherence were recruited from two public HIV care sites in South Africa. Internalized alcohol stigma, enacted alcohol stigma, internalized HIV stigma and phosphatidylethanol [PEth] levels, an alcohol use biomarker, were assessed at baseline, and three- and six-months post-baseline. Participants were randomized to a peer-delivered behavioral intervention or enhanced treatment as usual (facilitated referral to a co-located substance use treatment program). A cross-lagged panel structural equation model with three mediators was used to test lagged effects of stigma on PEth outcomes and whether stigma mediated the effects of the peer intervention.
Results
Significant lagged effects were identified such that higher levels of enacted alcohol stigma and internalized HIV stigma at baseline separately predicted higher PEth levels at three-month follow-up. Higher levels of internalized alcohol stigma predicted higher PEth levels at six-month follow-up. No significant intervention effects were found on stigma (ps > 0.05). Stigma did not mediate the effect of the intervention.
Conclusions
Findings suggest that higher HIV and alcohol stigma predict greater alcohol use. Future research should explore how stigma reduction strategies can be incorporated into peer-delivered interventions and evaluate the effects of reducing stigma on health outcomes.
{"title":"Effects of HIV and alcohol stigma on biomarker-confirmed alcohol use following a peer-delivered intervention in South Africa","authors":"Jennifer M. Belus , Morgan S. Anvari , Hongjie Ke , Kristen S. Regenauer , Tianzhou Ma , Bronwyn Myers , Lena S. Andersen , John A. Joska , Jessica F. Magidson","doi":"10.1016/j.abrep.2025.100640","DOIUrl":"10.1016/j.abrep.2025.100640","url":null,"abstract":"<div><h3>Background</h3><div>Despite documented relationships between multiple forms of stigma and health outcomes, limited research has examined the effects of both HIV and alcohol stigmas on objectively measured alcohol use. Research is needed to better understand relationships between stigma and health outcomes to inform intervention efforts that reduce stigma.</div></div><div><h3>Methods</h3><div>Participants (<em>N</em> = 60) who met criteria for unhealthy alcohol use and suboptimal HIV medication adherence were recruited from two public HIV care sites in South Africa. Internalized alcohol stigma, enacted alcohol stigma, internalized HIV stigma and phosphatidylethanol [PEth] levels, an alcohol use biomarker, were assessed at baseline, and three- and six-months post-baseline. Participants were randomized to a peer-delivered behavioral intervention or enhanced treatment as usual (facilitated referral to a co-located substance use treatment program). A cross-lagged panel structural equation model with three mediators was used to test lagged effects of stigma on PEth outcomes and whether stigma mediated the effects of the peer intervention.</div></div><div><h3>Results</h3><div>Significant lagged effects were identified such that higher levels of enacted alcohol stigma and internalized HIV stigma at baseline separately predicted higher PEth levels at three-month follow-up. Higher levels of internalized alcohol stigma predicted higher PEth levels at six-month follow-up. No significant intervention effects were found on stigma (<em>p</em>s > 0.05). Stigma did not mediate the effect of the intervention.</div></div><div><h3>Conclusions</h3><div>Findings suggest that higher HIV and alcohol stigma predict greater alcohol use. Future research should explore how stigma reduction strategies can be incorporated into peer-delivered interventions and evaluate the effects of reducing stigma on health outcomes.</div><div>Trial Registration: ClinicalTrials.gov NCT03529409.</div></div>","PeriodicalId":38040,"journal":{"name":"Addictive Behaviors Reports","volume":"22 ","pages":"Article 100640"},"PeriodicalIF":2.8,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145519534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-01DOI: 10.1016/j.abrep.2025.100639
Ayodeji Iyanda , Richard Adeleke , Omowunmi Iyanda
Background
Emergency room (ER) use reflects acute healthcare burden, but the roles of chronic health conditions (CHCs), substance use disorders (SUDs), drug use disorders (DUDs), and mental health conditions (MHCs) remain underexplored across populations.
Methods
Using nationally representative survey data (N = 226,838; weighted = 1,243,120,763), we applied survey-weighted logistic regression to examine predictors of ER visits. Covariates included CHCs, SUDs, DUDs, severity levels of these orders, MHCs, race/ethnicity, education, employment, residence, and body mass index.
Results
Adults with ≥ 1 CHC were more likely to visit the ER (OR = 1.72; 95 % CI: 1.60–1.85). DUD significantly increased ER use (OR = 1.70; 95 % CI: 1.54–1.88), while overall SUD was not significant after adjustment (OR = 1.05; 95 % CI: 0.98–1.12). Severe SUD elevated ER use even without CHCs (OR = 1.89; 95 % CI: 1.67–2.13). African Americans had higher odds of ER visits (OR = 1.28; 95 % CI: 1.21–1.36), and Native American/Alaska Natives were more likely to report DUD (OR = 1.55; 95 % CI: 1.31–1.82). Lower educational attainment (OR = 1.22; 95 % CI: 1.16–1.28) and unemployment (OR = 1.34; 95 % CI: 1.25–1.43) were linked to higher risks. MHCs predicted ER use (OR = 1.63; 95 % CI: 1.53–1.74) and substance-related disorders.
Conclusions
CHCs, DUD severity, and MHCs are strong predictors of ER utilization. Disparities among African Americans and Native American/Alaska Natives highlight the need for integrated care addressing chronic illness, behavioral health, and substance use—particularly for socioeconomically and racially marginalized groups.
{"title":"Compounding risks of chronic health conditions and substance use disorder on healthcare burden in the USA: Analysis of NSDUH data (2021–2023)","authors":"Ayodeji Iyanda , Richard Adeleke , Omowunmi Iyanda","doi":"10.1016/j.abrep.2025.100639","DOIUrl":"10.1016/j.abrep.2025.100639","url":null,"abstract":"<div><h3>Background</h3><div>Emergency room (ER) use reflects acute healthcare burden, but the roles of chronic health conditions (CHCs), substance use disorders (SUDs), drug use disorders (DUDs), and mental health conditions (MHCs) remain underexplored across populations.</div></div><div><h3>Methods</h3><div>Using nationally representative survey data (N = 226,838; weighted = 1,243,120,763), we applied survey-weighted logistic regression to examine predictors of ER visits. Covariates included CHCs, SUDs, DUDs, severity levels of these orders, MHCs, race/ethnicity, education, employment, residence, and body mass index.</div></div><div><h3>Results</h3><div>Adults with ≥ 1 CHC were more likely to visit the ER (OR = 1.72; 95 % CI: 1.60–1.85). DUD significantly increased ER use (OR = 1.70; 95 % CI: 1.54–1.88), while overall SUD was not significant after adjustment (OR = 1.05; 95 % CI: 0.98–1.12). Severe SUD elevated ER use even without CHCs (OR = 1.89; 95 % CI: 1.67–2.13). African Americans had higher odds of ER visits (OR = 1.28; 95 % CI: 1.21–1.36), and Native American/Alaska Natives were more likely to report DUD (OR = 1.55; 95 % CI: 1.31–1.82). Lower educational attainment (OR = 1.22; 95 % CI: 1.16–1.28) and unemployment (OR = 1.34; 95 % CI: 1.25–1.43) were linked to higher risks. MHCs predicted ER use (OR = 1.63; 95 % CI: 1.53–1.74) and substance-related disorders.</div></div><div><h3>Conclusions</h3><div>CHCs, DUD severity, and MHCs are strong predictors of ER utilization. Disparities among African Americans and Native American/Alaska Natives highlight the need for integrated care addressing chronic illness, behavioral health, and substance use—particularly for socioeconomically and racially marginalized groups.</div></div>","PeriodicalId":38040,"journal":{"name":"Addictive Behaviors Reports","volume":"22 ","pages":"Article 100639"},"PeriodicalIF":2.8,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145519561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-25DOI: 10.1016/j.abrep.2025.100638
Zachary Pierce-Messick , Kirsten E. Smith , Samuel F. Acuff , Derek D. Reed , David H. Epstein , Justin C. Strickland
Aims
Kratom products have increased in popularity in the United States due to their availability and their purported analgesic and stimulatory properties. We sought to examine if behavioral economic demand procedures widely used in addiction science would identify indicators of problematic kratom use and to evaluate the relative performance of differing demand approaches.
Methods
Respondents with a lifetime history of kratom use (N = 117) completed two versions of a hypothetical kratom purchase task. The first version (“Quantity”) followed typical purchase task methods; respondents were asked how much kratom they would purchase across various prices. The second version (“Likelihood”) asked how likely respondents would be to purchase a single dose of kratom across the same price range. Logistic regression was used to determine the association of demand indices with the likelihood of meeting KUD criteria.
Results
For the Quantity version, higher demand intensity (OR = 2.16, p = 0.01) and lower demand elasticity (OR = 0.45, p = 0.01) were significantly associated with past year but not lifetime KUD (p’s > 0.10). For the Likelihood version, demand intensity, demand elasticity, and Pmax were not associated with KUD (p’s > 0.10); higher breakpoint was associated with past year, but not lifetime KUD (OR = 1.44, p = 0.04).
Conclusions
This study is the first to demonstrate that purchase tasks can quantify the reinforcing efficacy of kratom and emphasizes the temporal specificity of the association between purchase tasks and problem behaviors. These findings also suggest that demand indices from Quantity- and Likelihood-based tasks differentially relate to KUD, emphasizing the importance of task and outcome selection.
AimsKratom产品在美国越来越受欢迎,因为它们的可用性和所谓的镇痛和刺激特性。我们试图检验在成瘾科学中广泛使用的行为经济需求程序是否能识别出有问题的kratom使用指标,并评估不同需求方法的相对表现。方法117名有终生使用克拉通史的被调查者完成了两个版本的假设克拉通购买任务。第一个版本(“数量”)遵循典型的购买任务方法;受访者被问及他们会在不同的价格下购买多少克朗。第二个版本(“可能性”)询问受访者在相同价格范围内购买单剂量kratom的可能性有多大。使用逻辑回归来确定需求指数与满足KUD标准的可能性之间的关系。结果对于数量版本,较高的需求强度(OR = 2.16, p = 0.01)和较低的需求弹性(OR = 0.45, p = 0.01)与过去一年显著相关,而与终生KUD无关(p 's > 0.10)。对于可能性版本,需求强度,需求弹性和Pmax与KUD无关(p 's > 0.10);较高的断点与过去年份相关,但与终生KUD无关(OR = 1.44, p = 0.04)。结论本研究首次证明了购买任务可以量化问题行为的强化效果,并强调了购买任务与问题行为之间关联的时间特异性。这些发现还表明,基于数量和可能性的任务的需求指数与KUD的关系不同,强调了任务和结果选择的重要性。
{"title":"Association of behavioral economic demand for kratom with DSM-5 use disorder: quantity and likelihood-based demand approaches","authors":"Zachary Pierce-Messick , Kirsten E. Smith , Samuel F. Acuff , Derek D. Reed , David H. Epstein , Justin C. Strickland","doi":"10.1016/j.abrep.2025.100638","DOIUrl":"10.1016/j.abrep.2025.100638","url":null,"abstract":"<div><h3>Aims</h3><div>Kratom products have increased in popularity in the United States due to their availability and their purported analgesic and stimulatory properties. We sought to examine if behavioral economic demand procedures widely used in addiction science would identify indicators of problematic kratom use and to evaluate the relative performance of differing demand approaches.</div></div><div><h3>Methods</h3><div>Respondents with a lifetime history of kratom use (N = 117) completed two versions of a hypothetical kratom purchase task. The first version (“Quantity”) followed typical purchase task methods; respondents were asked how much kratom they would purchase across various prices. The second version (“Likelihood”) asked how likely respondents would be to purchase a single dose of kratom across the same price range. Logistic regression was used to determine the association of demand indices with the likelihood of meeting KUD criteria.</div></div><div><h3>Results</h3><div>For the Quantity version, higher demand intensity (OR = 2.16, <em>p</em> = 0.01) and lower demand elasticity (OR = 0.45, <em>p</em> = 0.01) were significantly associated with past year but not lifetime KUD (<em>p</em>’s > 0.10). For the Likelihood version, demand intensity, demand elasticity, and Pmax were not associated with KUD (<em>p</em>’s > 0.10); higher breakpoint was associated with past year, but not lifetime KUD (OR = 1.44, <em>p</em> = 0.04).</div></div><div><h3>Conclusions</h3><div>This study is the first to demonstrate that purchase tasks can quantify the reinforcing efficacy of kratom and emphasizes the temporal specificity of the association between purchase tasks and problem behaviors. These findings also suggest that demand indices from Quantity- and Likelihood-based tasks differentially relate to KUD, emphasizing the importance of task and outcome selection.</div></div>","PeriodicalId":38040,"journal":{"name":"Addictive Behaviors Reports","volume":"22 ","pages":"Article 100638"},"PeriodicalIF":2.8,"publicationDate":"2025-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145465134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-20DOI: 10.1016/j.abrep.2025.100634
Esra Sünkel, Alla Machulska, Marie Neubert, Tobias Stalder, Tim Klucken
Background
Alcohol and tobacco use are leading causes of preventable mortality and transdiagnostic risk factors for poor health, especially in comorbid mental disorders. Identification and treatment in German healthcare remain inadequate. The WHO ASSIST is a brief screening tool for substance use, but the German self-report version has not been systematically validated for alcohol and tobacco. Methods: In a psychotherapeutic outpatient sample (N = 553; mean age 34.9, SD = 13.4, range 18–74; 60 % female), we evaluated (i) concurrent, (ii) construct, (iii) discriminative validity, and (iv) diagnostic accuracy of the alcohol (ASSISTA) and tobacco (ASSISTT) subscales. Results: Regarding concurrent validity, ASSISTA strongly correlated with AUDIT and showed weak correlation with clinical judgement, whereas ASSISTT correlated with FTND but not with clinical judgement. Construct validity was demonstrated by acceptable internal consistency and small correlations with ICD-10 alcohol and tobacco diagnoses. Discriminative validity was good for both subscales. Diagnostic accuracy analyses indicated that optimal cutoff values were substantially lower than the manual thresholds (alcohol 3.5/8.5 vs. 11/27, tobacco 5.5 vs. 27). Discussion: Our results support the validity of the German ASSISTA/T subscales. Comparison with established measures highlights clinical utility. ASSISTT‘s lack of correlation with clinical judgement suggests smoking might be under-recognized without standardized screening. We propose empirically derived cutoff values to improve sensitivity for detecting clinically relevant substance use in outpatient psychotherapy settings.
背景:酒精和烟草使用是可预防死亡的主要原因,也是健康状况不佳的跨诊断风险因素,特别是在共病性精神障碍中。德国医疗机构的诊断和治疗仍然不足。世卫组织ASSIST是一种药物使用的简短筛查工具,但德国的自我报告版本尚未对酒精和烟草进行系统验证。方法:在一份心理治疗门诊样本中(N = 553,平均年龄34.9,SD = 13.4,范围18-74,60%为女性),我们评估了酒精(ASSISTA)和烟草(ASSISTT)亚量表的(i)同期、(ii)结构、(iii)判别效度和(iv)诊断准确性。结果:在并发效度方面,ASSISTA与AUDIT呈强相关,与临床判断呈弱相关,而ASSISTA与FTND呈不相关。结构效度通过可接受的内部一致性和与ICD-10酒精和烟草诊断的小相关性来证明。两个分量表的判别效度均较好。诊断准确性分析表明,最佳临界值大大低于手动阈值(酒精3.5/8.5 vs 11/27,烟草5.5 vs 27)。讨论:我们的研究结果支持德国ASSISTA/T量表的有效性。与既定措施的比较突出了临床效用。ASSISTT与临床判断缺乏相关性表明,如果没有标准化的筛查,吸烟可能被低估。我们提出经验推导的截止值,以提高灵敏度检测临床相关的物质使用在门诊心理治疗设置。
{"title":"Assessment of alcohol and tobacco use in psychotherapy: validation of the german self-report ASSIST alcohol and tobacco subscales in an outpatient setting","authors":"Esra Sünkel, Alla Machulska, Marie Neubert, Tobias Stalder, Tim Klucken","doi":"10.1016/j.abrep.2025.100634","DOIUrl":"10.1016/j.abrep.2025.100634","url":null,"abstract":"<div><h3>Background</h3><div>Alcohol and tobacco use are leading causes of preventable mortality and transdiagnostic risk factors for poor health, especially in comorbid mental disorders. Identification and treatment in German healthcare remain inadequate. The WHO ASSIST is a brief screening tool for substance use, but the German self-report version has not been systematically validated for alcohol and tobacco. Methods: In a psychotherapeutic outpatient sample (<em>N</em> = 553; mean age 34.9, <em>SD</em> = 13.4, range 18–74; 60 % female), we evaluated (i) concurrent, (ii) construct, (iii) discriminative validity, and (iv) diagnostic accuracy of the alcohol (ASSIST<sub>A</sub>) and tobacco (ASSIST<sub>T</sub>) subscales. Results: Regarding concurrent validity, ASSIST<sub>A</sub> strongly correlated with AUDIT and showed weak correlation with clinical judgement, whereas ASSIST<sub>T</sub> correlated with FTND but not with clinical judgement. Construct validity was demonstrated by acceptable internal consistency and small correlations with ICD-10 alcohol and tobacco diagnoses. Discriminative validity was good for both subscales. Diagnostic accuracy analyses indicated that optimal cutoff values were substantially lower than the manual thresholds (alcohol 3.5/8.5 vs. 11/27, tobacco 5.5 vs. 27). Discussion: Our results support the validity of the German ASSIST<sub>A/T</sub> subscales. Comparison with established measures highlights clinical utility. ASSIST<sub>T</sub>‘s lack of correlation with clinical judgement suggests smoking might be under-recognized without standardized screening. We propose empirically derived cutoff values to improve sensitivity for detecting clinically relevant substance use in outpatient psychotherapy settings.</div></div>","PeriodicalId":38040,"journal":{"name":"Addictive Behaviors Reports","volume":"22 ","pages":"Article 100634"},"PeriodicalIF":2.8,"publicationDate":"2025-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145361058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}