Addictive Behaviors Reports最新文献_第2页

Social, Economic, and health risks among people who use Methamphetamine: Comparing three patterns of opioid Co-Use 甲基苯丙胺使用者的社会、经济和健康风险：比较阿片类药物共同使用的三种模式

IF 2.8 Q1 Psychology

Addictive Behaviors Reports

Pub Date : 2025-12-19 DOI: 10.1016/j.abrep.2025.100660

Kimberly Page , Mia Rae Kirk , Tristin Garcia , Haley Etchart , Benjamin Chase , Robert W. Harding , Jess Anderson , May McCarthy , Phillip Fiuty , Kathleen Reich , Kelly Mytinger , Olufemi Erinoso , Karla D. Wagner

Objectives

To examine how persons using different methamphetamine-opioid combinations differ with respect to social, risk, and health characteristics, and to identify patterns of vulnerability across simultaneous, sequential, and independent use.

Methods

414 people who use illicit drugs were surveyed, 384 of whom reported polydrug use involving methamphetamine, in Nevada and New Mexico between June 2022 and August 2023. Participants were classified into three mutually exclusive groups based on self-reported methamphetamine and opioid use patterns: simultaneous use (deliberately using both drugs together), sequential use (using both drugs but not deliberately using simultaneously), and independent use (using methamphetamine alone or with non-opioid drugs). Prevalence ratios were calculated to examine associations between use patterns and social, economic, health, and drug use characteristics.

Results

We identified three distinct use patterns: simultaneous (53.1%), sequential (17.7%), and independent (29.2%). Individuals in these risk groups exhibited differential social, economic, carceral, and health-related risk: those engaged in simultaneous showed higher vulnerability relative to people who use independently and sequentially. Healthcare engagement was associated with lower simultaneous use.

Conclusions

These findings suggest the need to support development of strategies to support transition from higher to lower-risk drug use patterns.

目的研究使用不同甲基苯丙胺-阿片类药物组合的人在社会、风险和健康特征方面的差异，并确定同时、连续和独立使用时的脆弱性模式。方法在2022年6月至2023年8月期间，对内华达州和新墨西哥州的414名使用非法药物的人进行了调查，其中384人报告使用包括甲基苯丙胺在内的多种药物。参与者根据自我报告的甲基苯丙胺和阿片类药物使用模式被分为三个相互排斥的组：同时使用（故意同时使用两种药物）、顺序使用（使用两种药物但不是故意同时使用）和独立使用（单独使用甲基苯丙胺或与非阿片类药物一起使用）。计算流行率以检查使用模式与社会、经济、健康和药物使用特征之间的关联。结果发现3种不同的使用模式：同时使用（53.1%）、顺序使用（17.7%）和独立使用（29.2%）。这些风险群体中的个体表现出不同的社会、经济、癌症和健康相关风险：与独立和顺序使用的人相比，同时使用的人表现出更高的脆弱性。医疗保健参与与较低的同时使用相关。结论这些发现表明，有必要支持制定策略，以支持从高风险药物使用模式向低风险药物使用模式的转变。

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引用次数: 0

Suicidal thoughts, problem gambling severity and utilisation of health care and social services: A population-based study in Finland 自杀念头、问题赌博严重程度和保健和社会服务的利用：芬兰的一项基于人口的研究

IF 2.8 Q1 Psychology

Addictive Behaviors Reports

Pub Date : 2025-12-19 DOI: 10.1016/j.abrep.2025.100658

Tiina Latvala , Maria Heiskanen , Virve Marionneau , Kalle Lind , Tanja Grönroos , Sari Castrén

Background

Persons harmed by problem gambling have an increased risk of suicide and suicidal thoughts. Social and health care services have an important role in recognising and supporting persons harmed by gambling problems and suicidal thoughts.

Methods

We analyse population-based survey data from the Healthy Finland survey of permanent Finnish residents aged 20 years or older (n = 28,154). We study associations between gambling and suicidal thoughts, and use of health care and social services among individuals engaged in gambling and experienced suicidal thoughts in the past year. The analysis uses χ² tests and logistic regression models.

Results

Of persons harmed by problem gambling (PGSI score ≥ 8) 31 % had suicidal thoughts. Among persons harmed by problem gambling and having suicidal thoughts, utilization of health care and social services was more common compared to non-gamblers with suicidal thoughts. Individuals who engaged in gambling and experienced suicidal thoughts in the past year but had not utilized health care services were more often young, male, and excessive alcohol users. On the contrary, those who had used social services, engaged in gambling and had suicidal thoughts were experiencing more often long-term illnesses and severe psychological distress.

Conclusions

Suicidal thoughts are prevalent among persons harmed by problem gambling. Social and health service systems need to better recognise the association between gambling and co-occurrent suicidal thoughts. In addition, services need to be developed to offer effective treatment and support with high levels of integration.

受问题赌博伤害的人有更高的自杀和自杀念头的风险。社会和保健服务在确认和支持受赌博问题和自杀念头伤害的人方面发挥着重要作用。方法：我们分析来自健康芬兰调查的人口调查数据，调查对象为年龄在20岁及以上的芬兰永久居民（n = 28,154）。我们研究赌博与自杀念头之间的联系，以及在过去一年中参与赌博并有过自杀念头的个人使用医疗保健和社会服务的情况。分析采用χ2检验和逻辑回归模型。结果受问题赌博伤害者（PGSI评分≥8）中有自杀念头的占31%。在受到问题赌博伤害并有自杀念头的人中，与有自杀念头的非赌徒相比，利用医疗保健和社会服务更为普遍。在过去一年中从事赌博和有自杀念头但没有利用保健服务的个人往往是年轻人、男性和酗酒者。相反，那些使用过社会服务、从事赌博和有自杀念头的人往往患有长期疾病和严重的心理困扰。结论受问题赌博伤害的人群普遍存在自杀念头。社会和卫生服务系统需要更好地认识到赌博与同时发生的自杀念头之间的联系。此外，需要开发服务，以提供有效的治疗和支持，并实现高水平的整合。

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引用次数: 0

Consumption patterns and withdrawal symptoms in dual cannabis-tobacco users in Spain: Cross-sectional study 西班牙大麻-烟草双重使用者的消费模式和戒断症状：横断面研究

IF 2.8 Q1 Psychology

Addictive Behaviors Reports

Pub Date : 2025-12-17 DOI: 10.1016/j.abrep.2025.100656

Judith Saura , Marta Enríquez , Ariadna Feliu , Xavier Roca , Silvia Mondón , Pablo Barrio , Magalí Andreu , Lidia Segura , Montse Ballbè , Marcela Fu , Esteve Fernández , Cristina Martínez , DuCATA clinical group

Background

Cannabis use has increased worldwide, with over 188 million users annually. In Spain, past-year prevalence among people aged 15–64 is 10.6%. Dual use of cannabis and tobacco is common, increasing health risks and complicating cessation. This study examines consumption patterns and cannabis withdrawal severity among dual users undergoing treatment for cannabis use disorder (CUD).

Method

A cross-sectional study was conducted in substance use treatment programs in Catalonia, Spain. Participants were cannabis users initiating CUD treatment. A questionnaire collected sociodemographic data, cannabis and tobacco use characteristics (e.g., number of spliffs, tobacco amount), nicotine dependence, motivation to quit, and cannabis withdrawal symptoms. Hierarchical cluster analysis using Gower’s distance identified behavioral patterns among participants.

Results

Data from 94 participants seeking CUD treatment were included. Daily tobacco use was reported by 91.5%, with a mean Fagerström score of 4.2/10. Most participants (88.1%) co-used cannabis with tobacco, and 75.8% experienced cannabis withdrawal symptoms, with women reporting greater severity. Cluster analysis revealed two profiles: Cluster 1 (71.0%) included mostly older males with higher motivation to quit and fewer withdrawal symptoms; Cluster 2 (29.0%) was younger, more sex-balanced, and showed higher nicotine dependence, and more severe withdrawal symptoms.

Conclusions

Co-use of cannabis and tobacco is highly prevalent among individuals entering CUD treatment. Higher nicotine dependence is associated with more severe withdrawal symptoms. Older males with higher motivation and fewer withdrawal symptoms may have better prognosis, highlighting motivation as cessation predictor. Findings underscore the need to enhance motivation to quit both substances and integrated treatment.

Trial registration number. The DuCATA project has been registered at Clinicaltrials.gov under the identifier [NCT05512091].

大麻的使用在世界范围内有所增加，每年有超过1.88亿人使用大麻。在西班牙，过去一年15-64岁人群的患病率为10.6%。大麻和烟草的双重使用很常见，增加了健康风险，并使戒烟复杂化。本研究调查了大麻使用障碍（CUD）治疗的双重使用者的消费模式和大麻戒断严重程度。方法对西班牙加泰罗尼亚地区的药物使用治疗方案进行横断面研究。参与者是开始CUD治疗的大麻使用者。问卷收集了社会人口统计数据、大麻和烟草使用特征（如吸食次数、烟草量）、尼古丁依赖、戒烟动机和大麻戒断症状。使用高尔距离的层次聚类分析确定了参与者之间的行为模式。结果纳入了94名寻求CUD治疗的参与者的数据。每天吸烟的比例为91.5%，平均Fagerström得分为4.2/10。大多数参与者（88.1%）同时使用大麻和烟草，75.8%的参与者出现过大麻戒断症状，其中女性报告的症状更严重。聚类分析显示两种情况：聚类1（71.0%）主要包括老年男性，戒烟动机较高，戒断症状较少；第2组（29.0%）更年轻，性别更平衡，尼古丁依赖程度更高，戒断症状更严重。结论大麻和烟草的双重使用在进入CUD治疗的个体中非常普遍。高度的尼古丁依赖与更严重的戒断症状相关。动机较高且戒断症状较少的老年男性可能预后较好，强调动机是戒烟的预测因素。研究结果强调，需要加强戒烟的动机和综合治疗。试验注册号。DuCATA项目已在Clinicaltrials.gov注册，注册号为[NCT05512091]。

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引用次数: 0

The association between fear of missing out and problematic smartphone use: A latent profile analysis of problematic social media use 害怕错过和有问题的智能手机使用之间的联系：对有问题的社交媒体使用的潜在特征分析

IF 2.8 Q1 Psychology

Addictive Behaviors Reports

Pub Date : 2025-12-17 DOI: 10.1016/j.abrep.2025.100655

Rocco Servidio , Paolo Soraci , Zsolt Demetrovics , Zsolt Horváth , Mark D. Griffiths

Problematic social media use (PSMU) has emerged as a societal and behavioral concern, especially among young adults. However, individual differences in symptom manifestation remain understudied. The present study adopted a person-centered approach to identify distinct profiles of PSMU and to examine the predictive roles of fear of missing out (FoMO), problematic smartphone use (PSU), age, and sex among a sample of 625 Italian university students aged 18 to 40 years (M = 25.31 years, SD = 5.85) who completed a self-report online survey. Using latent profile analysis (LPA) on a sample of Italian university students who use Instagram, five profiles were identified. Salience, tolerance, mood modification, withdrawal, and conflict symptoms sharply differentiated the high-risk with withdrawal symptom group from the other groups, supporting a cross-sectional pattern consistent with (but not demonstrating) a dimensional progression model. FoMO predicted high-risk with withdrawal symptoms and high-risk without withdrawal symptom membership, suggesting its role as an early vulnerability factor, whereas PSU strongly predicted high-risk with withdrawal symptoms classification. Sex differences also emerged, with females being more likely to belong to higher risk with withdrawal symptoms profiles. Analysis also indicated that younger participants were more at risk of belonging to the high-risk PSMU group. The findings offer nuanced insight into how psychological factors shape social online behavior and suggest tailored intervention strategies for users’ risk levels. However, the findings should be interpreted within the context of the Instagram social platform and the study’s sample-specific characteristics.

有问题的社交媒体使用（PSMU）已经成为一个社会和行为问题，尤其是在年轻人中。然而，症状表现的个体差异仍未得到充分研究。本研究采用以人为本的方法来确定PSMU的不同特征，并在625名18至40岁的意大利大学生（M = 25.31岁，SD = 5.85）中检查错过恐惧（FoMO），问题智能手机使用（PSU），年龄和性别的预测作用。通过对使用Instagram的意大利大学生样本进行潜在特征分析（LPA），确定了五种特征。显著性、耐受性、情绪改变、戒断和冲突症状显著地将高风险戒断症状组与其他组区分开来，支持与维度进展模型一致（但不证明）的横截面模式。FoMO预测有戒断症状的高风险和无戒断症状隶属的高风险，提示其作为早期脆弱性因素的作用，而PSU对有戒断症状分类的高风险具有较强的预测作用。性别差异也出现了，女性更有可能属于高风险的戒断症状。分析还表明，年轻的参与者属于高危PSMU组的风险更大。这些发现为心理因素如何影响社交网络行为提供了细致入微的见解，并为用户的风险水平提供了量身定制的干预策略。然而，这些发现应该在Instagram社交平台和研究样本特定特征的背景下进行解释。

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引用次数: 0

Attachment Representations, emotion regulation Difficulties and behavioral addiction Risk: Testing a mediation model in undergraduate students 依恋表征、情绪调节困难与行为成瘾风险：大学生依恋表征、情绪调节困难与行为成瘾风险的中介模型检验

IF 2.8 Q1 Psychology

Addictive Behaviors Reports

Pub Date : 2025-12-17 DOI: 10.1016/j.abrep.2025.100657

Francesca Favieri , Giuseppe Forte , Maria Casagrande , Renata Tambelli

Behavioral addictions are increasingly common among adolescents and young adults, especially in the context of digital and compulsive behaviors. This study examined whether emotion dysregulation mediates the relationship between insecure attachment representations and behavioral addiction risk. A total of 418 undergraduate students (59.1 % female; M = 20.00, SD = 1.51; age range = 18–22 years) completed self-report measures on attachment style, emotion regulation, and behavioral addiction. Multiple regressions and mediation analyses were conducted. Results indicated that insecure attachment—particularly Preoccupation with Relationships and Need for Approval—was linked to greater behavioral addiction risk. This association was partly explained by emotion dysregulation, suggesting that difficulties in managing emotions heighten the impact of insecure attachment on maladaptive behaviors. These findings highlight the contribution of early relational vulnerabilities and emotion dysregulation deficits to behavioral addiction risk in emerging adulthood and suggest emotion regulation as a key target for prevention.

行为成瘾在青少年和年轻人中越来越普遍，尤其是在数字和强迫行为的背景下。本研究探讨情绪失调是否介导不安全依恋表征与行为成瘾风险之间的关系。共418名大学生（女生59.1%,M = 20.00, SD = 1.51，年龄18-22岁）完成了依恋类型、情绪调节和行为成瘾的自我报告测量。进行多元回归和中介分析。结果表明，不安全的依恋——尤其是对人际关系的关注和对认可的需求——与更大的行为成瘾风险有关。这种关联部分可以用情绪失调来解释，这表明管理情绪的困难会加剧不安全依恋对适应不良行为的影响。这些发现强调了早期关系脆弱性和情绪失调缺陷对成年早期行为成瘾风险的贡献，并表明情绪调节是预防的关键目标。

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引用次数: 0

Exploring the effects of cannabidiol on pain sensitivity using quantitative sensory testing among individuals receiving methadone or buprenorphine for opioid use disorder: an open-label, proof-of-concept study 在接受美沙酮或丁丙诺啡治疗阿片类药物使用障碍的个体中，使用定量感官测试探索大麻二酚对疼痛敏感性的影响：一项开放标签，概念验证研究

IF 2.8 Q1 Psychology

Addictive Behaviors Reports

Pub Date : 2025-12-14 DOI: 10.1016/j.abrep.2025.100654

Gabriel P.A. Costa , Rebecca Suh , Mehmet Sofuoglu , Joao P. De Aquino

While medications for opioid use disorder (MOUD) effectively treat opioid use disorder (OUD), concurrent pain management remains challenging. Cannabidiol (CBD) shows promise in both pain management and OUD treatment. This open-label, proof-of-concept study aimed to evaluate the safety and tolerability of cannabidiol (CBD) and explore its utility for pain sensitivity using quantitative sensory testing (QST) among individuals with co-occurring OUD and chronic pain. Seven individuals with OUD receiving methadone or buprenorphine and experiencing chronic pain completed three test sessions with ascending oral CBD doses (400 mg, 800 mg, 1200 mg). QST analyses for pain sensitivity showed no significant main effects of CBD dose or time but revealed a significant MOUD x CBD dose interaction for heat pain threshold and tolerance. Post-hoc comparisons indicated that participants receiving buprenorphine exhibited significantly higher heat threshold (400 mg) and heat tolerance (800 mg) compared to those receiving methadone. Descriptively, the 400 mg CBD dose was associated with the most favorable pain response patterns across several QST measures in the buprenorphine group. CBD was well-tolerated across all doses; no serious adverse events, changes in subjective effects, or adverse cognitive effects on verbal memory were reported. In conclusion, this pilot study offers preliminary indications that CBD’s impact on pain sensitivity varies by dose and MOUD type, notably with potential benefits at 400 mg for individuals on buprenorphine. Coupled with its demonstrated safety and tolerability, these findings support future larger, placebo-controlled randomized trials to confirm CBD’s therapeutic utility for pain in this population.

虽然阿片类药物使用障碍（mod）药物有效治疗阿片类药物使用障碍（OUD），但并发疼痛管理仍然具有挑战性。大麻二酚（CBD）在疼痛管理和OUD治疗中都显示出前景。这项开放标签的概念验证研究旨在评估大麻二酚（CBD）的安全性和耐受性，并通过定量感觉测试（QST）在并发OUD和慢性疼痛的个体中探索其对疼痛敏感性的效用。7名OUD患者接受美沙酮或丁丙诺啡治疗并经历慢性疼痛，完成了三次递增的口服CBD剂量（400毫克、800毫克、1200毫克）的测试。疼痛敏感性的QST分析显示，CBD剂量或时间没有显著的主要影响，但显示了mod与CBD剂量对热痛阈值和耐受性的显著相互作用。事后比较表明，与接受美沙酮治疗的参与者相比，接受丁丙诺啡治疗的参与者表现出明显更高的热阈值（400毫克）和耐热性（800毫克）。描述性地说，在丁丙诺啡组的几个QST测量中，400 mg CBD剂量与最有利的疼痛反应模式相关。CBD在所有剂量下都具有良好的耐受性；没有严重的不良事件、主观效应的改变或对言语记忆的不良认知影响的报道。总之，这项初步研究提供了初步迹象，表明CBD对疼痛敏感性的影响因剂量和mod类型而异，特别是对于服用丁丙诺啡的个体，400毫克的潜在益处。再加上其已证明的安全性和耐受性，这些发现支持未来更大规模的安慰剂对照随机试验，以确认CBD对这一人群疼痛的治疗效用。

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引用次数: 0

The mediating role of anxiety and depression symptoms in the relationship between ADHD symptoms and polysubstance use among French university students: the i-share study 焦虑和抑郁症状在法国大学生ADHD症状与多物质使用关系中的中介作用：i-share研究

IF 2.8 Q1 Psychology

Addictive Behaviors Reports

Pub Date : 2025-12-13 DOI: 10.1016/j.abrep.2025.100652

François A.M. Jean , Charline Galesne , Noelia Retuerto , Marie C. Navarro , Zeineb Azouz , Agathe Tabyaoui , Mélissa Macalli , Christophe Tzourio , Cédric Galéra

Introduction

Polysubstance use, depressive disorder, and anxiety disorder are frequent comorbidities in adults with ADHD. This study aimed to explore the mediation role of anxiety and depression symptoms in the association between ADHD symptoms and polysubstance use.

Methods

The study included 1675 French university students from February 2013 to July 2020 as part of the i-Share cohort. Time 1: ADHD symptoms were assessed using the Adult ADHD Self-Report Scale. Time 2: Anxiety and depression symptoms were evaluated using the State-Trait Anxiety Inventory-Y trait and the Patient Health Questionnaire-9, respectively. Time 3: Substance use was assessed through a self-reported questionnaire. We conducted a mediation analysis using structural equation modeling.

Results

The study included 1675 participants. At time 1, the level of ADHD symptoms was moderate (m: 10.66, sd: 3.99). At time 2, both anxiety (m: 47.11, sd: 10.57) and depression (m: 6.92, sd: 5.33) symptoms were moderate. At time 3, 93.49% (1566) of participants had used substances. The direct effect between ADHD factor and polysubstance use factor was of 1.66 (1.04–2.48). The indirect effects between ADHD factor and polysubstance use factor were through anxiety factor −0.68 (−1.15 to −0.37) and through depression factor −0.57 (−0.94 to −0.32). Although the mediation effects through anxiety and depression factors were negative, the total effect remained positive and significant (0.41 (0.27 to 0.59)).

Discussion

Anxiety factor and depression factor acted as negative and partial mediators in the association between ADHD factor and polysubstance use factor.

多物质使用、抑郁障碍和焦虑障碍是成人ADHD患者常见的合并症。本研究旨在探讨焦虑和抑郁症状在ADHD症状与多物质使用之间的中介作用。该研究纳入了2013年2月至2020年7月的1675名法国大学生，作为i-Share队列的一部分。时间1：使用成人ADHD自我报告量表评估ADHD症状。时间2：分别使用状态-特质焦虑量表- y和患者健康问卷-9评估焦虑和抑郁症状。时间3：通过自我报告的问卷来评估药物使用情况。我们使用结构方程模型进行了中介分析。结果该研究包括1675名参与者。在时间1时，ADHD症状水平为中度（m: 10.66, sd: 3.99）。在时间2时，焦虑（m: 47.11, sd: 10.57）和抑郁（m: 6.92, sd: 5.33）症状均为中度。在第3期，93.49%（1566人）的参与者使用过药物。ADHD因子与多物质使用因子的直接影响系数为1.66（1.04 ~ 2.48）。ADHD因子与多物质使用因子的间接影响分别为焦虑因子- 0.68（- 1.15 ~ - 0.37）和抑郁因子- 0.57（- 0.94 ~ - 0.32）。虽然焦虑和抑郁因素的中介作用为负，但总效应仍为正且显著（0.41(0.27 ~ 0.59)）。讨论焦虑因素和抑郁因素在ADHD因素与多物质使用因素之间起负向和部分中介作用。

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引用次数: 0

Reduced Environmental Stimulation Therapy (REST) in methamphetamine use disorder: a pilot study 减少环境刺激疗法（REST）在甲基苯丙胺使用障碍：一项试点研究

IF 2.8 Q1 Psychology

Addictive Behaviors Reports

Pub Date : 2025-12-13 DOI: 10.1016/j.abrep.2025.100651

Emily M. Choquette , McKenna Garland , Gregory Morrissey , Nicolas Wilzok , Raminta Wilson , Abhinita Premkumar , Jennifer L. Stewart , Sahib S. Khalsa

Existing treatments for methamphetamine use disorder (MUD) are suboptimal in addressing withdrawal and preventing relapse. Models of addiction have proposed that negative affect plays an influential role in drug craving and relapse. Although Reduced Environmental Stimulation Therapy (REST) has been associated with attenuated negative affect in other psychiatric conditions, it has not been examined as an intervention for MUD. To address this gap, the present study investigated the feasibility, tolerability, and safety of a single session of REST via floatation pool (pool-REST) in treatment-enrolled individuals with MUD. In a within-subject crossover design, participants (n = 78) consented to complete one session each of pool-REST and chair-REST, an active comparator controlling for the effects of simple relaxation and expectation. Feasibility was assessed via completion rate, tolerability via duration of REST utilization, and safety via adverse event incidence. Secondary outcomes were assessed via measurement of self-reported affect, interoceptive sensation, and degree of stimulant craving. 74 % of all recruited participants (n = 58) completed both REST sessions, which were well-tolerated. There were no serious adverse events and participants provided more frequent endorsements of positive versus negative experiences. Although both REST conditions showed significant decreases in ratings of stress/anxiety, negative affect, and stimulant craving, pool-REST was associated with greater increases in positive affect, cardiorespiratory interoceptive awareness, heart rate, and systolic blood pressure than chair-REST. These results demonstrate that REST sessions are feasible, well-tolerated, and safe in individuals with MUD. Randomized control trials are warranted to explore potential salutary effects of pool-REST on MUD remission and recovery.

现有的甲基苯丙胺使用障碍（MUD）治疗在解决戒断和预防复发方面是次优的。成瘾模型提出，负面影响在药物渴求和复发中起着重要作用。虽然减少环境刺激疗法（REST）与其他精神疾病的负面情绪减轻有关，但尚未对其作为MUD的干预措施进行研究。为了解决这一差距，本研究调查了通过漂浮池（pool-REST）对治疗入组的MUD患者进行单次REST的可行性、耐受性和安全性。在受试者交叉设计中，参与者（n = 78）同意完成pool-REST和chair-REST各一个阶段，这是一个控制简单放松和期望影响的主动比较者。可行性通过完成率评估，耐受性通过REST使用时间评估，安全性通过不良事件发生率评估。次要结果通过测量自我报告的情感、内感受和兴奋剂渴望程度来评估。所有招募的参与者中有74% （n = 58）完成了两个REST会话，耐受性良好。没有严重的不良事件，参与者提供的积极体验比消极体验更频繁。尽管两种休息方式在压力/焦虑、负面影响和兴奋剂渴望方面的评分都显著降低，但池式休息与椅子式休息相比，在积极影响、心肺内感受性意识、心率和收缩压方面有更大的增加。这些结果表明REST会话在MUD患者中是可行的、耐受性良好且安全的。随机对照试验是有必要的，以探索池- rest对MUD缓解和恢复的潜在有益影响。

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引用次数: 0

Substance use treatment and overdose patterns in high and low social vulnerability counties: a trends analysis in New Jersey from 2014–2022 高和低社会脆弱性县的物质使用治疗和过量模式：2014-2022年新泽西州的趋势分析

IF 2.8 Q1 Psychology

Addictive Behaviors Reports

Pub Date : 2025-12-12 DOI: 10.1016/j.abrep.2025.100653

Sarah E. Cooper , Lara V. Fougnies , Alyssa M. Juntilla , Holly H. Lister , Katie Hilton , Jamey J. Lister

Introduction

This study investigates trends in substance use treatment admissions and overdose patterns across New Jersey counties from 2014 to 2022. Using the Social Vulnerability Index (SVI), we examined how county-level vulnerability differentiates treatment utilization and overdose outcomes.

Materials and Methods

We created a novel, longitudinal data set using data from multiple public sources. Data were obtained and analyzed for all 21 New Jersey counties. Outcome measures included substance use treatment admissions, opioid-specific treatment admissions, overdose deaths, and naloxone administration. Using the SVI, counties were categorized as either high (n = 10) or low (n = 11) social vulnerability. Data analyses were conducted using joinpoint analysis to identify trends over time and variation by social vulnerability status.

Results

Significant trends were identified regardless of social vulnerability status for all outcome measures, appearing as upward trends in initial segments and flat or declining trends in latter segments. High vulnerability (compared to low vulnerability) counties demonstrated greater Annual Percentage Change (APC) magnitudes for all outcome measures in the initial segment, similar APCs in the latter segment, and had higher baseline rates and peak rates.

Conclusions

Findings demonstrate that county-level social vulnerability status is associated with substance use treatment admissions and overdose patterns. Specifically, high vulnerability counties exhibit consistently higher rates of substance use treatment admissions, naloxone administrations, and overdose deaths. This pattern highlights a need for expanded substance use services along the continuum of care for vulnerable areas and the viability of SVI status as a useful and simple tool for targeting service expansion efforts.

本研究调查了2014年至2022年新泽西州各县药物使用治疗入院和过量模式的趋势。使用社会脆弱性指数（SVI），我们研究了县级脆弱性如何区分治疗利用和过量结果。材料和方法我们使用来自多个公共来源的数据创建了一个新颖的纵向数据集。获得并分析了新泽西州所有21个县的数据。结果测量包括药物使用治疗入院、阿片类药物特异性治疗入院、过量死亡和纳洛酮给药。使用SVI，县被划分为高（n = 10）或低（n = 11）社会脆弱性。数据分析采用连接点分析，以确定随时间变化的趋势和社会脆弱性状况的变化。结果无论社会脆弱性状况如何，在所有结果测量中都发现了显著的趋势，在初始阶段呈上升趋势，在后期阶段呈持平或下降趋势。高脆弱性县（与低脆弱性县相比）在初始阶段的所有结果测量中显示出更大的年百分比变化（APC）幅度，在后一阶段的APC相似，并且具有更高的基线率和峰值率。结论县级社会脆弱性状况与药物使用治疗入院和过量用药模式相关。具体来说，高脆弱性县一贯表现出较高的药物使用治疗入院率、纳洛酮用药率和过量死亡率。这一模式突出表明，需要在对脆弱地区的连续护理过程中扩大药物使用服务，并突出表明，将特殊受害人地位作为针对扩大服务努力的有用和简单的工具是可行的。

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引用次数: 0

Associations between substance use treatment and ketamine use: A hypothesis-generating analysis 药物使用治疗和氯胺酮使用之间的联系：一种假设生成分析

IF 2.8 Q1 Psychology

Addictive Behaviors Reports

Pub Date : 2025-12-10 DOI: 10.1016/j.abrep.2025.100650

Fares Qeadan, Shanti O’Neil

Background

Ketamine is increasingly used in clinical settings for mental health and pain management, yet its misuse poses public health risks. While prior studies have examined ketamine trends, few have explored its use among individuals receiving treatment for substance use disorders (SUD).

Methods

Using 2021–2023 data from the National Survey on Drug Use and Health (NSDUH), we analyzed the association between past-year ketamine use and receipt of SUD treatment among U.S. residents aged 12 and older. Stratified analyses by substance type and use category (use, misuse, and disorder) were conducted using adjusted logistic regression models.

Results

Among 173,808 participants who reported substance use, 3.19 % received past-year treatment and 0.26 % reported past-year ketamine use. Ketamine use was more common among those in treatment (1.39 %) than not (0.22 %). Across SUD strata, treatment was associated with higher odds of ketamine use, including alcohol SUD (aOR = 2.73; 95 % CI: 1.58–4.71), marijuana SUD (2.32; 1.34–4.02), inhalant SUD (5.22; 1.96–13.94), methamphetamine SUD (5.10; 2.08–12.48), pain reliever SUD (2.62; 1.16–5.90), and opioid SUD (2.76; 1.23–6.18). Among misuse strata, associations included pain relievers (2.69; 1.40–5.16), opioids (3.13; 1.71–5.74), and psychotherapeutics (2.09; 1.21–3.62). Among use strata, treatment was associated with higher odds for cigarettes, alcohol, marijuana, heroin, PCP, DMT/AMT/FOXY, methamphetamine, pain relievers, tranquilizers, and stimulants.

Conclusions

Past-year treatment is a marker of elevated ketamine exposure across multiple substance domains. Findings are hypothesis-generating and underscore the need for clinical screening, patient education on unsupervised ketamine risks, and research clarifying timing, intent, and outcomes of ketamine use in SUD populations.

氯胺酮越来越多地用于心理健康和疼痛管理的临床环境，但其滥用构成公共卫生风险。虽然先前的研究已经检查了氯胺酮的趋势，但很少有人探索其在接受物质使用障碍治疗的个体中的使用。方法利用美国国家药物使用与健康调查（NSDUH）的2021-2023年数据，分析美国12岁及以上居民过去一年氯胺酮使用与接受SUD治疗的关系。采用调整后的logistic回归模型对物质类型和使用类别（使用、误用和障碍）进行分层分析。结果在报告药物使用的173,808名参与者中，3.19%的人在过去一年中接受过治疗，0.26%的人在过去一年中使用过氯胺酮。氯胺酮在治疗中的使用（1.39%）比未使用（0.22%）更为常见。在整个SUD层中，治疗与氯胺酮使用的高发生率相关，包括酒精SUD （aOR = 2.73; 95% CI: 1.58-4.71）、大麻SUD（2.32; 1.34-4.02）、吸入剂SUD（5.22; 1.96-13.94）、甲基苯丙胺SUD（5.10; 2.08-12.48）、止痛药SUD（2.62; 1.16-5.90）和阿片类药物SUD（2.76; 1.23-6.18）。在滥用人群中，相关因素包括止痛药（2.69;1.40-5.16）、阿片类药物（3.13;1.71-5.74）和精神治疗药物（2.09;1.21-3.62）。在使用人群中，治疗与香烟、酒精、大麻、海洛因、PCP、DMT/AMT/FOXY、甲基苯丙胺、止痛药、镇定剂和兴奋剂的几率较高相关。结论过去一年的治疗是氯胺酮暴露在多个物质领域升高的标志。研究结果是假设的产生，强调了临床筛查的必要性，对患者进行无监督氯胺酮风险的教育，以及澄清氯胺酮在SUD人群中使用的时间、意图和结果的研究。

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引用次数: 0