Interdisciplinary Neurosurgery: Advanced Techniques and Case Management最新文献

{"title":"Prevalence of burnout syndrome in Brazilian neurosurgery residents: A nationwide questionnaire-based survey","authors":"Rhuann Pontes dos Santos Silva ,&nbsp;Isadora Gomes Mesquita ,&nbsp;Louise Makaren Oliveira ,&nbsp;Marcia Mitie Nagumo ,&nbsp;Julia Costa Justo ,&nbsp;Gabriela Fernandes de Oliveira Pessoa ,&nbsp;Eberval Gadelha ,&nbsp;Luis Alencar Borba ,&nbsp;Cleice Mara Goncalves Coelho ,&nbsp;Jonas Byk ,&nbsp;Juscimar Carneiro ,&nbsp;Otávio da Cunha Ferreira Neto ,&nbsp;José Marcus Rotta ,&nbsp;Wellingson Silva Paiva ,&nbsp;Robson Luis Oliveira de Amorim","doi":"10.1016/j.inat.2025.102160","DOIUrl":"10.1016/j.inat.2025.102160","url":null,"abstract":"<div><h3>Background</h3><div>Burnout syndrome (BS) is a significant issue among neurosurgery residents, resulting from chronic emotional and interpersonal stressors. Characterized by emotional exhaustion, depersonalization, and low personal accomplishment, BS can lead to decreased productivity, interpersonal relationships, and medical errors.</div></div><div><h3>Objective</h3><div>This study aims to analyze the prevalence of BS among Brazilian neurosurgery residents and identify associated factors.</div></div><div><h3>Methods</h3><div>We conducted a cross-sectional study using the Maslach Burnout Inventory (MBI) and questionnaires covering sociodemographic information, mental health, and job satisfaction.</div></div><div><h3>Results</h3><div>The study surveyed all Brazilian neurosurgery residency programs, with 118 out of 600 residents (19.6 %) responding. The prevalence of BS was 64.1 %, and 94.9 % had at least one high domain. Third-year residents exhibited the highest rate of burnout (79.2 %). Gender significantly influenced burnout rates, with males showing higher levels. Additionally, dissatisfaction with personal life and insufficient physical exercise were associated with increased likelihood of burnout. They also exhibited higher dissatisfaction with their academic productivity, time for study, and balance between professional and personal life. Suicidal ideation was reported by 16.1 % of residents but was not statistically associated with BS. Multivariate analysis showed that only male sex was an independent variable of having BS (OR 2.97 95CI 1.005–8.78, p = 0.049). Also, those with BS were less likely to choose neurosurgery again (OR 0.22 95CI 0.06–0.78, p = 0.02) or recommend it as a specialty (OR 0.32 95CI 0.11–0.93, p = 0.03)</div></div><div><h3>Conclusion</h3><div>This study highlights the high prevalence of BS among Brazilian neurosurgery residents, indicating a need for targeted interventions to address these stressors and improve resident well-being.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"43 ","pages":"Article 102160"},"PeriodicalIF":0.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145978164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of early surgical outcomes for posterior fossa lesions using the far lateral approach: Single-surgeon series from Vietnam","authors":"Duy Pham ,&nbsp;Son Tung Tran ,&nbsp;Le Minh Tien Nguyen ,&nbsp;Trong Hiep Nguyen ,&nbsp;Minh Quang Ngo ,&nbsp;Hung Manh Ngo","doi":"10.1016/j.inat.2025.102190","DOIUrl":"10.1016/j.inat.2025.102190","url":null,"abstract":"<div><h3>Background</h3><div>The Far Lateral Approach (FLA) is a neurosurgical access for lesions at the foramen magnum and lower clival regions, where the brainstem, cranial nerves IX-XII, and vertebral artery converge. This surgical approach allows safe access to lesions in the posterior fossa, both anterior and lateral to the brainstem, while minimizing tissue damage. Although widely reported worldwide, no data have been published in Vietnam.</div></div><div><h3>Objectives</h3><div>To evaluate the feasibility, safety, and surgical outcomes of the FLA in managing posterior fossa lesions from a single-surgeon series in Vietnam.</div></div><div><h3>Materials and methods</h3><div>This prospective cross-sectional study was conducted on seven patients who underwent microsurgery via the FLA for posterior fossa lesions between January 2022 and January 2025.</div></div><div><h3>Results</h3><div>The cohort included five women and two men, aged 30–64 years (mean 51.7 ± 14.5). Diagnoses included four meningiomas (two lower clival, two foramen magnum meningiomas), one neurinoma, one neurenteric cyst, and one vertebral artery aneurysm. All procedures were performed by the same surgical team following a standardized protocol. Gross total resection was achieved in all tumor cases. No major complications such as meningitis, hemiplegia, or perioperative mortality were observed. Minor complications included transient lower cranial nerve deficits (hoarseness, dysphagia) and cerebrospinal fluid (CSF) leakage, which resolved with conservative management.</div></div><div><h3>Conclusion</h3><div>The FLA is safe and effective for managing posterior fossa lesions at the foramen magnum and lower clival regions, and can be successfully applied in Vietnam. It provides wide exposure while preserving critical neurovascular structures, with favorable outcomes and manageable complications.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"43 ","pages":"Article 102190"},"PeriodicalIF":0.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145939394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical exposure to neurosurgery at medical school: The current medical student experience","authors":"Aled Lester ,&nbsp;Ronak Ved ,&nbsp;Gregor Ramage ,&nbsp;Stephen Greenwood ,&nbsp;Daniel Parry ,&nbsp;Paul Leach ,&nbsp;Phil Smith","doi":"10.1016/j.inat.2025.102185","DOIUrl":"10.1016/j.inat.2025.102185","url":null,"abstract":"<div><h3>Background</h3><div>Medical students may be placed at neurosurgical centres (NCs) or non-neurosurgical centres (non-NCs) during their undergraduate clinical neurosciences placements (CNP). Studies show varied exposure to neurosurgery among medical schools, but comparison of clinical exposure between students at neurosurgical centres and non-neurosurgical centres or its impact on their preparedness, is yet to be fully assessed.</div></div><div><h3>Methods</h3><div>A questionnaire was electronically distributed to medical students from Cardiff University in the United Kingdom, all of whom completed a clinical neurosciences placement. Recruitment was through email, social media, and in-person. Quantitative data were analysed using descriptive statistics and non-parametric tests, while qualitative data underwent thematic analysis.</div></div><div><h3>Results</h3><div>Forty responses were collected from medical students. Thirty-four (85.0 %) had their clinical neurosciences placement at a neurosurgical centre, and of these, twenty-four (70.6 %) had a neurosurgical rotation, half of which lasted ≤ two days. Significantly more participants at neurosurgical centres attended neurosurgical theatre compared to none at non-neurosurgical centres (54.8 % vs 0.0 %, p = 0.022). Significant differences were found in neurosurgical tutorials, small group teaching, case-based discussions, and simulations, with these opportunities being more commonly provided at neurosurgical centres. Three themes from the qualitative data supported the quantitative findings.</div></div><div><h3>Conclusion</h3><div>There is a difference in clinical exposure between students at neurosurgical centres and non- neurosurgical centres. Students at non-neurosurgical centres have fewer neurosurgical opportunities, potentially impacting their learning, examination performance, and clinical practice.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"43 ","pages":"Article 102185"},"PeriodicalIF":0.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145939390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of the treatment pathway and causes of delay in a young patient with spinal arteriovenous malformations: A case report","authors":"Guiying Liu ,&nbsp;Lifang Wen ,&nbsp;Yanyan Zhang ,&nbsp;Dan Zhao ,&nbsp;Ling Tang ,&nbsp;Xin Guan","doi":"10.1016/j.inat.2025.102159","DOIUrl":"10.1016/j.inat.2025.102159","url":null,"abstract":"<div><h3>Background</h3><div>Spinal arteriovenous malformations (SAVMs) are rare, Early insidious, non-specific symptoms cause diagnostic delay—higher in adolescents—leading to psychological distress, educational interruption, poor prognosis, and more. Timely intervention improves outcomes, but research on young patients’ pre-admission clinical trajectory is limited.</div></div><div><h3>Case presentation</h3><div>A 20-year-old male with 1-month lower limb weakness/numbness and sphincter disturbance was diagnosed with SAVMs. Initial low back pain was ignored due to his intense training but symptoms progressed to urinary/defecatory dysfunction. Spinal CT was normal, MRI showed T9-L3 abnormal signals and T8-T12 spinal cord edema. Even with worsening symptoms every day the time from the discovery of the symptoms to the acceptance of the correct treatment was 40 days.</div></div><div><h3>Intervention</h3><div>The young man had endovascular embolization (DSA + EMB) at a tertiary hospital. Access to the right common femoral artery was gained via the Seldinger method, delivering embolic agents(N-butyl cyanoacrylate NBCA) into this vessel, control angiography confirmed a significant reduction in both blood flow velocity and volume within the malformed vasculature. Post-rehabilitation, 3-month follow-up showed normal walking, recovered defecation, Urinary Functionand improved neurological function (Aminoff &amp; Logue Scale changed from 7to 0.</div></div><div><h3>Conclusion</h3><div>Diagnostic delays stem from atypical symptoms, primary physicians’ limited experience, and poor early screening. Strategies like physician training, optimized diagnostics, and public education are recommended to improve timely SAVM care.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"43 ","pages":"Article 102159"},"PeriodicalIF":0.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145939474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A new thrombectomy method using proximal balloon-guided aspiration from the common carotid artery for internal carotid artery occlusion","authors":"Takuya Nakamura ,&nbsp;Yoshiki Hanaoka ,&nbsp;Satoshi Kitamura ,&nbsp;Jun-ichi Koyama ,&nbsp;Tetsuyoshi Horiuchi","doi":"10.1016/j.inat.2025.102186","DOIUrl":"10.1016/j.inat.2025.102186","url":null,"abstract":"<div><h3>Background and purpose</h3><div>Internal carotid artery (ICA) occlusion is associated with poor clinical outcomes due to high clot burden and complications. Although several devices such as aspiration catheters and stent retrievers have improved recanalization rates, they carry risks including vessel dissection, carotid-cavernous fistula, vessel perforation, and stent detachment. To address these, we developed a new thrombectomy method using a balloon-guided catheter aspiration from the common carotid artery (CCA) to achieve complete recanalization and minimize device-related complications.</div></div><div><h3>Material and methods</h3><div>We report five consecutive cases of ICA occlusion treated between October 2022 and November 2023 using proximal balloon-guided aspiration from the CCA. An 8F or 9F balloon guide catheter was positioned in the CCA, and proximal manual aspiration was performed following balloon inflation to achieve flow arrest and prevent clot migration. We evaluated puncture to recanalization time, modified TICI grade, and device-related complications.</div></div><div><h3>Results</h3><div>All cases achieved mTICI 2b or 3 recanalization without any device-related complications. Particularly, three of five cases achieved mTICI 3 recanalization in a single pass. One case experienced embolization to a new territory, which was associated with concomitant external carotid artery occlusion. The mean time from puncture to recanalization was 49.2 min.</div></div><div><h3>Conclusion</h3><div>Proximal balloon-guided aspiration from the CCA provides high recanalization rates for ICA occlusion. This method was simpler and faster, more cost-effective, and associated with lower complication risks than conventional mechanical thrombectomy. However, there is a risk of external carotid artery occlusion due to vascular collapse during aspiration. Further investigation is needed to clarify the potential risks and limitations of this method.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"43 ","pages":"Article 102186"},"PeriodicalIF":0.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145939472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hydatid cyst of the medulla oblongata: rare presentation and surgical management","authors":"Hanan Ghanem ,&nbsp;George Elian Makhoul ,&nbsp;Mohammad Eyad Takahji ,&nbsp;Rima Alassaad ,&nbsp;Laila Alhaj Hussaen ,&nbsp;Loulitta Nicola Melhem ,&nbsp;Saleem Mazen Aslan ,&nbsp;Mohamad Kadi","doi":"10.1016/j.inat.2026.102208","DOIUrl":"10.1016/j.inat.2026.102208","url":null,"abstract":"<div><h3>Background</h3><div>Hydatid disease is a zoonotic parasitic infection that typically involves the lungs and liver. Primary intracranial cysts, especially in the brainstem, are extremely rare and rarely reported. We present a complex case of a brainstem hydatid cyst in a patient with a history of aqueductal stenosis and ventriculoperitoneal shunt placement, successfully managed with surgical intervention.</div></div><div><h3>Case presentation</h3><div>A 28-year-old woman with a history of aqueductal stenosis and prior ventriculoperitoneal shunt surgeries presented with an 18-month history of headache, dysarthria, dysphagia, ataxia, and dysmetria. Neurological examination confirmed cerebellar signs. A brain MRI revealed a well-defined cystic lesion in the medulla oblongata. Hydatid disease was suspected, even though serology and abdominal imaging were negative. The lesion was surgically treated using a modified PAIR (Puncture, Aspiration, Injection, and Re-aspiration) technique. The diagnosis of hydatid cyst was confirmed by histopathological examination. We have administered postoperative antiparasitic therapy, and the patient showed marked clinical improvement and a stable situation at six-month follow-up.</div></div><div><h3>Conclusion</h3><div>Our case describes the rare occurrence of a hydatid cyst in the brainstem. We emphasize the need to consider hydatid disease in the differential diagnosis of brainstem lesions, particularly in endemic regions, and underscore the diagnostic and therapeutic challenges associated with such unusual presentations.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"43 ","pages":"Article 102208"},"PeriodicalIF":0.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147419833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dural fistula visualized by intradural reflux of epidural blood patch − potential role of atlantoaxial hypermobility in intracranial hypotension","authors":"Issei Shimamura ,&nbsp;Eiichi Nakai ,&nbsp;Hitoshi Fukuda ,&nbsp;Tetsuya Ueba","doi":"10.1016/j.inat.2026.102240","DOIUrl":"10.1016/j.inat.2026.102240","url":null,"abstract":"<div><h3>Background</h3><div>Intracranial hypotension can occur at any age and commonly presents with orthostatic headache. Dural rupture is a major underlying cause; however, its precise pathophysiological mechanisms remain incompletely understood. Although cerebrospinal fluid (CSF) leakage may be detected by imaging, direct identification of the responsible fistula is often difficult. In particular, the relationship between mechanical stress and the morphology or extent of dural disruption has not been fully elucidated. The aim of this report is to present a rare case in which intrathecal reflux during an epidural blood patch allowed direct visualization of a cervical dural defect, providing insight into possible mechanisms of dural sac disruption in intracranial hypotension.</div></div><div><h3>Case Description</h3><div>A 56-year-old woman presented with progressive orthostatic headache. Brain MRI demonstrated bilateral chronic subdural hematomas, and lumbar puncture revealed an unmeasurably low CSF pressure, leading to a diagnosis of intracranial hypotension. She had no history of trauma but reported habitual prolonged smartphone use in the prone position with cervical hyperextension. CT myelography suggested CSF leakage at the C1/2 level.</div><div>A targeted epidural blood patch (EBP) was performed at C1/2 using autologous blood mixed with 10% iopamidol. Post-procedural CT revealed continuous contrast passage across the dura beneath the left posterior arch of C1, indicating intrathecal reflux through a focal dural fistula. Although the first EBP provided only partial symptomatic relief, the radiological findings strongly suggested a large dural defect at the same level. A second targeted EBP was therefore performed at C1/2, resulting in complete symptom resolution. Follow-up imaging confirmed spontaneous resolution of the chronic subdural hematomas.</div></div><div><h3>Conclusions</h3><div>This case suggests that repetitive or excessive cervical mechanical stress may induce focal detachment at the dural–osseous interface, resulting in dural fistula formation and intracranial hypotension. Direct visualization of intrathecal contrast reflux during EBP allowed precise localization of a rare atlantoaxial dural fistula. These findings provide insight into a potential cervical pathomechanism of intracranial hypotension and may help refine diagnostic and therapeutic strategies.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"43 ","pages":"Article 102240"},"PeriodicalIF":0.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147420730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microsurgical treatment of intracranial dural arteriovenous fistula and prognosis analysis","authors":"Lijiu Chen,&nbsp;Zhiqiang Yu,&nbsp;Cheng Qiu,&nbsp;Guangxu Zhang,&nbsp;Jinbing Zhao,&nbsp;Shengxue He","doi":"10.1016/j.inat.2025.102175","DOIUrl":"10.1016/j.inat.2025.102175","url":null,"abstract":"<div><h3>Objective</h3><div>To summarize and analyze the curative effect of 46 patients with intracranial dural arteriovenous fistula (DAVF) treated by microsurgery, explore the prognostic factors of DAVF, and summarize the skills and experience of surgical treatment.</div></div><div><h3>Methods</h3><div>46 patients with DAVF admitted to the cerebrovascular disease Treatment Center of Nanjing Brain Hospital from March 2017 to September 2023 were retrospectively analyzed, and the curative effect was summarized. Gender, age, number of supplying arteries, cortical drainage veins, location of fistula and intracranial hemorrhage were selected as subvariables. Meanwhile, CT, MRI, DSA and prognostic follow-up data before discharge and 6 to 12 months after operation were collected for Logistic regression analysis.</div></div><div><h3>Results</h3><div>There were no deaths in 46 DAVF patients during the perioperative period, and 45 of them (97.83 %) reached the standard of imaging cure. The clinical symptoms of 42 cases (91.3 %) were significantly improved or disappeared, and the good prognosis rate (GOS ≥ 4 points) was 95.65 % (44/46).</div></div><div><h3>Conclusion</h3><div>Microsurgical treatment of DAVF can directly cut the fistula, with a high complete cure rate and a low recurrence rate. For patients with complex multiple fistula, intraoperative exploration and repeated application of ICG angiography can greatly reduce the risk of residual and recurrence, and effectively improve the prognosis of patients.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"43 ","pages":"Article 102175"},"PeriodicalIF":0.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145939389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rosai-Dorfman disease – Isolated intracranial localization: A case report and literature review","authors":"Kaloyan Ivanov ,&nbsp;Ivan Angelov ,&nbsp;Ridian Nedelko ,&nbsp;Deyan Dzhenkov","doi":"10.1016/j.inat.2025.102170","DOIUrl":"10.1016/j.inat.2025.102170","url":null,"abstract":"<div><div>Rosai-Dorfman Syndrome – Sinus histiocytosis is a benign disease with idiopathic etiology, primarily presenting with cervical lymphadenopathy and a febrile-intoxication syndrome but it can also affect other organs and systems such a skin, bones, orbit, central nervous system. Isolated intracranial localization is rare. It occurs more frequently in children and young adults but it can affect individuals of any age. In this article, we present a clinical case of a 67-year-old woman with a clinical picture of sudden-onset speech disturbances and a generalized tonic-clonic seizure. Imaging studies revealed an intracranial mass located in the left parietal region, appearing as a meningioma. Cytological and immunohistochemical examinations demonstrated an infiltrate of lymphocytes, plasma cells, and histiocytes expressing protein S-100 and CD68. Also described is the phenomenon of emperipolesis – the presence of intracytoplasmic lymphocytes within histiocytes.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"43 ","pages":"Article 102170"},"PeriodicalIF":0.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145939477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Two cases of rare multinodular vacuolated neuronal tumors (MVNT)","authors":"Ruijie Ma ,&nbsp;Zheng-Qing Hu ,&nbsp;Xiaoting Xing ,&nbsp;Dayong Xia","doi":"10.1016/j.inat.2025.102178","DOIUrl":"10.1016/j.inat.2025.102178","url":null,"abstract":"<div><div>Multinodular vacuolar neurocytoma (MVNT) is a relatively uncommon benign neuroepithelial tumor with fewer than 200 documented cases in the literature to date^1,9. The present report details two cases of frontal lobe MVNT. A 37-year-old female patient incidentally revealed a left frontal cingulate lesion (previously misdiagnosed as enlarged perivascular spaces [PVSs]), with no history of seizures, trauma, or family history of tumours. The second case study concerned a 53-year-old female patient with a two-year history of right frontal lobe lesions and a one-year history of seizures, which were controlled with oxcarbazepine. The two tumours exhibited typical MVNT imaging features: T1-weighted low signal intensity (lower than adjacent gray/white matter signal), T2-weighted high signal intensity (approaching cerebrospinal fluid signal), T2-FLAIR non-suppressed high signal intensity, and no contrast enhancement. No peritumoral edema or mass effect was observed. No peritumoral edema or mass effect. Follow-up (3–24 months) confirmed lesion stability. In this case report, we aim to raise awareness of the disease and avoid misdiagnosis and overtreatment.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"43 ","pages":"Article 102178"},"PeriodicalIF":0.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145978166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}