Voprosy Prakticheskoi Pediatrii最新文献

{"title":"Assessment of spraying characteristics of two nasal sprays containing framycetin","authors":"S. Gribanova, V. Yankova, O. Gobyzov, M. Ryabov, A. Karpova, S. Kedik, I. Udyanskaya, V. Grigorieva, I. I. Krasnyuk (jr.), T. Slonskaya, A.A. Zhukova","doi":"10.20953/1817-7646-2022-2-109-116","DOIUrl":"https://doi.org/10.20953/1817-7646-2022-2-109-116","url":null,"abstract":"Objective. To compare spraying characteristics of two nasal sprays containing framycetin – Isofra and Tramicent Materials and methods. We used a silicone model of the nasal cavity (Koken Co. Ltd., Tokyo, Japan) to assess dose distribution of the drug inside the nose. Shadow photography was applied to analyze dynamic characteristics of spraying and the dispersed composition of spray particles. Results. Using a silicone model, we evaluated the dose distribution of the spray inside the nasal cavity. We compared dose distribution of two nasal sprays containing framycetin (Isofra and Tramicent) with full and half-full bottles. Shadow photography was applied to evaluate dynamic characteristics of these sprays, including total duration of spraying, duration of its individual phases, spraying angle, as well as dispersion characteristics, such as average particle size and particle size distributions. Conclusion. The experiments with a silicone nose model demonstrated that Isofra ensured a larger distribution area inside the nasal cavity compared to Terramycin, which suggests a better coverage of the nasal mucosa with Isofra. Comparison of dynamic spraying characteristics (including duration of spraying phases, spraying angle, and shape of the cone) between Isofra and Tramicent using shadow photography showed that Isofra ensured a more homogenous spraying coverage with fine particles. Comparison of the dispersion composition of the two sprays showed that most of the Isofra dose was sprayed with smaller drops than Tramicent, which indicates a better dispersion of Isofra. Our findings suggest that Isofra ensured high quality spraying and effective delivery of the medicine into the nasal cavity. Key words: framycetin, spray, silicone nose model, shadow photography, spray characteristics","PeriodicalId":38157,"journal":{"name":"Voprosy Prakticheskoi Pediatrii","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67742225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alternative anticonvulsants in neonatology","authors":"Vladimir Perfilyev, A. G. Miroshnichenko, V. Zhelev, E. V. Devald","doi":"10.20953/1817-7646-2022-4-76-83","DOIUrl":"https://doi.org/10.20953/1817-7646-2022-4-76-83","url":null,"abstract":"The approaches to pharmacotherapy of neonatal seizures are always empirical and vary across the globe. There is still no consensus on this issue because of the highly variable efficacy of anticonvulsants traditionally used in newborns. Currently, none of these drugs has sufficient evidence to make an unambiguous conclusion on their efficacy and safety. Therefore, the search for new anticonvulsants for newborns is highly relevant. This review aims to summarize existing literature surrounding anticonvulsants that can potentially be used in newborns. It discusses advantages and disadvantages, as well as their utility in neonatal care. It also summarizes the latest information on neonatal seizures and outlines future directions of research to create new therapeutic strategies for neonatal seizures. Key words: anticonvulsant, treatment, neonatal seizures, newborns, anticonvulsant therapy, anticonvulsants, seizures","PeriodicalId":38157,"journal":{"name":"Voprosy Prakticheskoi Pediatrii","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67747472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac and vegetative manifestations of long-COVID in children","authors":"E. Degtyareva, A. Gorelov, H. Simonovskaya, E. P. Isaeva, M. A. Kufa, M. Kantemirova, A.S. Aleksandrova, V. Barskiy, A.S. Zakrevskij","doi":"10.20953/1817-7646-2022-5-75-82","DOIUrl":"https://doi.org/10.20953/1817-7646-2022-5-75-82","url":null,"abstract":"Approximately 5–15% of children develop post-COVID-19 syndrome after SARS-CoV-2 infection, which manifests itself with various pathological symptoms for more than 12 weeks. Cardiovascular symptoms range from serious myocardial inflammation, manifestations of essential hypertension to signs of autonomic dysfunction with a tendency to hypersympathicotonia, which negatively affects the quality of life of children. We report a case of subacute myocarditis in a patient with long-COVID after a low-symptomatic acute disease. This case illustrates high clinical significance of timely diagnosis of long-COVID using gadolinium-enhanced magnetic resonance imaging, which was performed in our country for the first time in pediatric practice. We developed criteria for early diagnosis of autonomic dysfunction specific for children and adolescents. We also developed treatment recommendations, including behavioral therapy, drug, and non-drug treatments. Key words: long-COVID, autonomic dysfunction, hypersympathicotonia, myocarditis, behavioral therapy, non-drug treatment","PeriodicalId":38157,"journal":{"name":"Voprosy Prakticheskoi Pediatrii","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67748204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative analysis of physical development indicators of adolescent boys in the 20th and 21st centuries (secular trend) on the model of the Republic of Dagestan","authors":"K. G. Kamalov, A. Arslanbekova, D.A. Arslanbekova, I. M. Magomedova","doi":"10.20953/1817-7646-2022-1-142-149","DOIUrl":"https://doi.org/10.20953/1817-7646-2022-1-142-149","url":null,"abstract":"The study of the physical development of adolescent population in the Republic of Dagestan is insufficient and attracts the attention of endocrinologists. A detailed examination of the features of physical development in this region could help to clarify the general patterns of acceleration or deceleration taking place in this territory of the Russian Federation. Objective. To conduct a comparative analysis of physical development indicators of adolescent boys during puberty in 1970-1990 with similar indicators of 2005-2010. Methods. The physical development of adolescents aged 11-17 years was examined in the mountain, foothill, and plain ecological and geographical zones of the Republic of Dagestan. Results. The physical development of boys aged 11-14 years in all ecological and geographical zones of the Republic of Dagestan in both groups was comparable (p > 0.05). Adolescents in the older age group of 15-16 years (group 1) outperformed their peers (group 2) by an average of 0.6-2.1%. From the age of 16, there was a “crossing” of the centile curves of physical development, and adolescents aged 16–17 years (group 2) already outperformed their peers (group 1) in all ecological and geographical zones of the Republic of Dagestan. This was most evident when comparing the physical development of the boys living in the foothill zone, where this difference was significant at 4.0-7.5% (p < 0.04) when comparing the two age groups (group 1 and 2). Final height by the end of puberty in adolescents in group 1 was in the range of 152.0 ± 2.7 cm and 163.0 ± 1.3 cm and in group 2 – 156.3 ± 0.7 cm and 167.7 ± 0.9 cm. Conclusion. The analysis and general secular trend of physical development indicators of adolescents at the turn of the 20th and 21st centuries on the model of the Republic of Dagestan showed that anthropometric parameters of adolescents in the Russian Federation demonstrate the presence of specific regional features – environmental, socio-economic, and anthropogenic. Key words: anthropometric data, Republic of Dagestan, retrospective indicators of adolescents, secular trend, comparative analysis, physical development","PeriodicalId":38157,"journal":{"name":"Voprosy Prakticheskoi Pediatrii","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67741129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expected effect of palivizumab on the reduction of infant mortality and hospitalizations rates due to respiratory syncytial virus infection","authors":"M. Zhuravleva, Yu. V. Gagarina, T. V. Marin, G. Asmolova, Yu. A. Sigova, I. Krsheminskaya, D. Ovsyannikov","doi":"10.20953/1817-7646-2022-2-55-64","DOIUrl":"https://doi.org/10.20953/1817-7646-2022-2-55-64","url":null,"abstract":"Objective. To assess the impact of preventive therapy with palivizumab against respiratory syncytial viral (RSV) infection on the indicator of the implementation of the Unified plan to achieve national goals of the Russian Federation and on the infant mortality rate. Patients and methods. Preterm infants born prior to 35 weeks gestation were considered as target population for immunization with palivizumab. We modeled an increase in palivizumab coverage to 25% by 2024 and calculated the expected number of deaths and hospitalizations that can be prevented using palivizumab. We also calculated targeted values of infant mortality reduction (for the entire country and individual regions) that can be achieved by increasing palivizumab coverage. Results. Annual increase of RSV prophylaxis coverage will prevent 49, 63 and 76 deaths in Russia in 2022, 2023, and 2024, respectively. This will ensure a 36.3%, 48.4%, and 60.5% reduction in infant mortality in 2022, 2023, and 2024, respectively, which will facilitate the achievement of targeted indicators specified in the National development goals of the Russian Federation. Moreover, it will prevent 904, 1142, and 1381 hospitalizations due to RSV in 2022, 2023, and 2024, respectively. Conclusion. Wider use of palivizumab will decrease the hospitalization rate and will facilitate the achievement of the targeted indicator ‘reduction of infant mortality’ within the Federal Project ‘Improvement of children's healthcare.’ Key words: infant mortality, preterm infants, palivizumab, prevention, respiratory syncytial virus infection","PeriodicalId":38157,"journal":{"name":"Voprosy Prakticheskoi Pediatrii","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67743395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pancreatitis in children with cystic fibrosis and preserved pancreatic exocrine function","authors":"A. Voronkova, E. Kondratyeva, E. Nikolaeva, E. Pasnova, I. R. Fatkhullina, N. Odinaeva","doi":"10.20953/1817-7646-2022-3-120-127","DOIUrl":"https://doi.org/10.20953/1817-7646-2022-3-120-127","url":null,"abstract":"The pancreas is one of the main organs affected by the dysfunction of the cystic fibrosis transmembrane conductance regulator (CFTR) protein. Pancreatitis can be a symptom of cystic fibrosis (CF) or a CFTR-related disorder. Genetic variants of the CFTR gene causing CF or having varying clinical significance are observed in 32–48% of patients. Approximately 20% of patients with mild genotypes are expected to develop pancreatitis. We report three cases of pancreatitis in children with CF and preserved pancreatic function. We focus on the challenges associated with the assessment of pancreatic insufficiency grade, suffering of children with recurrent acute and chronic pancreatitis, difficulties associated with the diagnosis and interpretation of laboratory parameters, problems of prognosis of pancreatitis development and progression in patients with pathogenic variants of the CFTR gene. Patients with mild pathogenic variants of the CFTR gene can have their pancreatic elastase-1 level reduced over time, which necessitates its annual monitoring. Patients with mild pathogenic variants should be routinely tested for pancreatic amylase, lipase, and diastase; and undergo examination using visualization methods. All CF patients require complete genotype verification to identify those with a mild genotype. Patients with recurrent pancreatitis should be checked for heterozygous pathogenic variants of the CFTR gene or CF verification. Key words: CFTR gene, cystic fibrosis, mild genotype, pancreas, pancreatitis, pancreatic elastase","PeriodicalId":38157,"journal":{"name":"Voprosy Prakticheskoi Pediatrii","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67744340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gut-bone axis: current concepts of interactions","authors":"A. Khavkin, V. Novikova, A. Vashura, T. Kovtun","doi":"10.20953/1817-7646-2022-5-66-74","DOIUrl":"https://doi.org/10.20953/1817-7646-2022-5-66-74","url":null,"abstract":"The discovery of the gut-bone axis promoted the development of treatment strategies aimed to preserve bone mineral density. Probiotics and probiotic complexes in combination with bone mineral matrix are gradually becoming a new treatment method for osteoporosis. This literature review aims to explore the role of gut microbiota in osteoclastogenesis, bone healing, mechanisms of its effects, and possible ways to modify the microbiota in order to improve bone metabolism. Key words: gut microbiota-bone axis, osteogenesis, osteoporosis, microbiota, nutritional support, baby formula, inulin","PeriodicalId":38157,"journal":{"name":"Voprosy Prakticheskoi Pediatrii","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67747247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Infants after artificial lung ventilation. New approaches to rehabilitation","authors":"P. V. Morozov, S.V. Novoseltsev","doi":"10.20953/1817-7646-2022-1-24-35","DOIUrl":"https://doi.org/10.20953/1817-7646-2022-1-24-35","url":null,"abstract":"Objective. To improve rehabilitation of infants who received respiratory support at birth. Patients and methods. This prospective comparative study was conducted in the Children's City Polyclinic No 13 of Yekaterinburg and included 131 infants who received different types of artificial lung ventilation (ALV) for some respiratory disorders. All patients were followed up by a pediatrician, neurologist, pulmonologist, and an infectious disease specialist; all of them received appropriate therapy. The experimental group comprised 99 infants who additionally received a course of osteopathic (manual) correction for 8–10 weeks, whereas the control group included 32 infants who received standard therapy only. Patients in the experimental and control groups were matched for all parameters. In addition to chest X-ray, all study participants underwent an assessment of their neurological, somatic, and biomechanical statuses. Osteopathic treatment (4 to 6 sessions lasting 30–40 minutes each) was performed by one osteopathic doctor. Statistical analysis was conducted using the SPSS Statistics.26 software; we calculated Pearson's linear correlation coefficient and used Fisher's exact test and McNemar's test. Differences were considered significant at p < 0.05. Results. Seventy-nine infants (79.8%) initially had both neurological and somatic disorders. Ten patients (10.1%) had either somatic disorders (such as labored nasal breathing, regurgitation, constipation, thermoregulation disorder) or neurological disorders (weather sensitivity, sleep disorders, delayed motor and/or neuropsychiatric development, impaired blood and cerebrospinal fluid dynamics) alone. We identified three groups of major somatic dysfunctions (SDs) in the biomechanical status: local (levels: С0–СI, sternum, thoracoabdominal diaphragm, sacrum); regional (cervical spine–level СII–СVI, laryngopharyngeal complex, lungs, abdominal cavity, skull); and global dysfunction of the dura mater. After treatment, the frequency of all neurological and somatic disorders, as well as the frequency of all SDs reduced in the experimental group (p < 0.001). Pathological changes on chest X-rays (elevated diaphragm, low mobility of the thoracic diaphragm, bullae, pleurodiaphragm atic adhesions, etc.) were detected in 89 patients (67.9%), including 66 infants from the experimental group (66.7%) and 23 infants from the control group (71.8%). Osteopathic (manual) treatment significantly reduced the number of patients with abdominal diaphragm dysfunction (56.6% vs. 26.3%), bullae (35.3% vs. 11.1%), and middle lobe syndrome (8.1% vs. 2%) (p < 0.001). The number of patients with thoracoabdominal diaphragm dysfunction in the control group did not change (n = 18; 56.2%). Positive radiological dynamics was observed in 90.9% of patients from the experimental group and 43.5% of patients from the control group. Moreover, only infants from the control group demonstrated negative radiological dynamics (17.4%). Conclusion. Newb","PeriodicalId":38157,"journal":{"name":"Voprosy Prakticheskoi Pediatrii","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67741667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of remission in children with systemic juvenile idiopathic arthritis receiving biologicals (tocilizumab and canakinumab): a cohort study","authors":"E. Krekhova, E. Alexeeva, T. Dvoryakovskaya, K. Isaeva, R. Denisova, A.L. Chomakhidze, O. Lomakina, A. Mamutova, A. Fetisova, M. Gautier, K. Chibisova, I. Kriulin, I. Tsulukiya","doi":"10.20953/1817-7646-2022-1-95-112","DOIUrl":"https://doi.org/10.20953/1817-7646-2022-1-95-112","url":null,"abstract":"Therapy with biologicals at the onset of systemic juvenile idiopathic arthritis (sJIA) ensures faster achievement of inactive disease or remission in more patients compared to standard treatment. Identification of predictors of early response to biologicals is necessary to increase treatment efficacy in children with sJIA. Objective. To develop a model for predicting treatment outcomes with different biologicals in sJIA patients. Materials and methods. We analyzed medical records of sJIA patients who received tocilizumab or canakinumab and were admitted to the Department of Rheumatology between July 2009 and February 2021. Predicted outcomes included inactive disease after 12 months of therapy with biologicals (according to C. Wallace criteria and JADAS71) and drug-free remission (without biologicals) for at least 6 months. Potential predictors comprised patient demographic and clinical characteristics, such as sJIA activity, CHAQ index, concomitant therapy, treatment outcomes after 1 and 3 months of therapy, etc. (115 parameters in total). Independent predictors were chosen using multivariate binary logistic regression. Results. This study included 250 patients receiving tocilizumab and 73 patients receiving canakinumab. After 12 months of tocilizumab therapy, 179 patients (76%) achieved inactive disease according to C. Wallace criteria and 170 patients (72%) achieved remission according to JADAS71 index. Drug-free remission (for at least 6 months without biologicals) was registered in 51 patients (20%) from the tocilizumab group. In the canakinumab group, inactive disease according to C. Wallace criteria, remission according to JADAS71, and drug-free remission were achieved in 58 (79%), 58 (79%), and 10 (14%) patients, respectively. Duration of morning stiffness at sJIA onset, dynamics of the duration of morning stiffness after 1 and 3 months of treatment, disease activity evaluated by a physician using the 100-mm visual analog scale (VAS) after one month of therapy, and patientreported overall well-being evaluated using VAS after 3 months of therapy were found to be the predictors of achieving remission according to C. Wallace criteria in the tocilizumab group. The following factors were significantly associated with remission according to JADAS71 index: duration of morning stiffness at sJIA onset and upon treatment initiation, VAS score evaluated by a physician after 1 and 3 months, and number of painful joints after 3 months. We also found several predictors of achieving drug-free remission, including lymphocyte count at disease onset, therapy with glucocorticoids (GCs) and its duration by the time of biological initiation, ESR upon treatment initiation, 50% improvement according to ACR pediatric criteria after 1 month, administration of systemic GCs after 1 month, ESR dynamics by 3 months, and number of joints with limited motion after 3 months. In the canakinumab group, the following factors were associated with remission according to C.Wa","PeriodicalId":38157,"journal":{"name":"Voprosy Prakticheskoi Pediatrii","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67742190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute hemorrhagic edema of infancy","authors":"P. Ostadrahimi, M. Sheikh, Elham Safaryzadeh","doi":"10.20953/1817-7646-2022-2-164-166","DOIUrl":"https://doi.org/10.20953/1817-7646-2022-2-164-166","url":null,"abstract":"Acute hemorrhagic edema of childhood, also called acute hemorrhagic edema of infancy (AHEI) or Finkelstein-Seidlmayer disease is a vasculitis of small blood vessels. The etiology of the disease is unknown, but various reports in the literature indicate precursor triggers including a preceding infectious disease. This article presents a clinical observation of an 8-month-old boy with ecchymotic skin lesions on legs and ears as well as genital edema, with a history of mild upper respiratory infection two weeks before referral. Laboratory findings were normal. After a few days, he was discharged without particular treatment. Despite the low prevalence of this disease, it is important to consider it during examinations due to the clinical nature of the diagnosis. Based on clinical and laboratory findings, a diagnosis of AHEI was made. We decided not to perform any therapy, and after about two weeks lesions had a self-limited resolution. The child was monitored clinically for about six months, and he did not present any relapse of the disease during the follow-up period. This patient was admitted to the hospital, underwent important laboratory tests, and was evaluated by multiple subspecialty services prior to diagnosis. While keeping in mind more worrisome diagnoses, physicians should consider the diagnosis of AHEI in well-appearing young children with purpuric lesions on the face and ears and non-pitting edema of the extremities. Awareness and early recognition of AHEI may prevent hospital admission, invasive workup, and parental and physician concern. Key words: acute hemorrhagic edema of infancy, Finkelstein-Seidlmayer disease, vasculitis","PeriodicalId":38157,"journal":{"name":"Voprosy Prakticheskoi Pediatrii","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67742786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}