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2009 International Conference on Biomedical and Pharmaceutical Engineering最新文献

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Geometrical and texture features estimation of lung cancer and TB images using chest X-ray database 基于胸片数据库的肺癌和结核图像几何和纹理特征估计
Pub Date : 2009-12-01 DOI: 10.1504/IJBET.2011.040453
S. Patil, V. Udupi, C. D. Kane, A. Wasif, J. V. Desai, A. Jadhav
Early detection is the most promising way to enhance a patient's chance for survival of lung cancer. One of the most important tasks in medical image analysis is to detect the absence or presence of disease in an image, without having precise delineations of pathology available for training. A computer algorithm for nodule detection in chest radiographs is presented. The algorithm consists of four main steps: (i) image acquisition (ii) image pre-processing; (iii) nodule candidate detection; (iv) feature extraction. Algorithm is applied on two main types of lung cancer images, like Small-Cell, Non-Small-Cell type and as well as on TB database. Total 75 images are used (25 from each category) during experiment to estimate geometrical and texture features. Active Shape Model (ASM) technique is used for lung field segmentation. Gray Level Co-occurrence Matrix (GLCM) technique is used to estimate texture features.
早期发现是提高肺癌患者生存机会的最有希望的方法。医学图像分析中最重要的任务之一是检测图像中疾病的缺失或存在,而没有精确的病理描述可用于训练。提出了一种胸片结节检测的计算机算法。该算法包括四个主要步骤:(i)图像采集;(ii)图像预处理;(iii)结节候选检测;(iv)特征提取。该算法主要应用于两种类型的肺癌图像,如小细胞肺癌、非小细胞肺癌和结核病数据库。实验中总共使用了75张图像(每类25张)来估计几何和纹理特征。采用主动形状模型(ASM)技术进行肺场分割。灰度共生矩阵(GLCM)技术用于纹理特征的估计。
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引用次数: 32
A comparison analysis between partial least squares and Neural Network in non-invasive blood glucose concentration monitoring system 偏最小二乘法与神经网络在无创血糖监测系统中的比较分析
Pub Date : 2009-12-01 DOI: 10.1109/ICBPE.2009.5384079
Chuah Zheng Ming, P. Raveendran, Poh Sin Chew
A non-invasive blood glucose monitoring system with six laser diodes is used to obtain a total of 290 NIR spectra from the Oral Glucose Tolerance Test (OGTT) experiment with the participation of a healthy volunteer over 4 days. Each laser diode operates at the discrete wavelengths between 1500nm and 1800nm with the power of 6mW each. A comparative analysis using the Partial Least Squares (PLS) model and the Neural Network (NN) model is studied. The study shows that the NN model performs better than the PLS model due to the presence of nonlinearity in the collected data. The presence of the nonlinearity is tested by using the Durbin-Watson test.
在健康志愿者参与的为期4天的口服葡萄糖耐量试验(OGTT)实验中,使用了一个带有6个激光二极管的无创血糖监测系统,共获得290个近红外光谱。每个激光二极管的工作波长在1500nm和1800nm之间,每个功率为6mW。对偏最小二乘(PLS)模型和神经网络(NN)模型进行了对比分析。研究表明,由于所收集的数据中存在非线性,神经网络模型的性能优于PLS模型。采用Durbin-Watson检验来检验非线性的存在。
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引用次数: 6
Formulation and physical characterization of microemulsions containing isotretinoin 含异维甲酸微乳的配方及物理性质
Pub Date : 1900-01-01 DOI: 10.1109/ICBPE.2009.5384088
Suria Ramli, Benjamin P. Ross, I. Gentle
Physical properties of microemulsions containing tween80 as surfactant and tetraglycol as cosurfactant, were investigated for their potential to form microemulsion templates as drug delivery vehicles for isotretinoin. Bile salt was used as edge activator in skin permeation and surfactant protein B (SP-B1–25) may be helpful in drug delivery and reducing sebum level. All of the compounds used to formulate the microemulsions were pharmaceutically acceptable and biocompatible. The drug-containing systems were characterized in regard to their transdermal parameters. Physiologically well-tolerated and physically stable multiple-component systems were developed. The concentrations of surfactants and cosurfactants which are necessary to form stable systems were evaluated. Microemulsions were characterized using polarized light microscopy, photon correlation spectroscopy (PCS), electric conductivity and rheometry. The influence of isotretinoin on the physical parameters of the preparation was investigated.
以吐温80为表面活性剂,四甘醇为助表面活性剂的微乳液的物理性质,研究了它们作为异维a酸药物递送载体形成微乳液模板的潜力。胆汁盐被用作皮肤渗透的边缘激活剂,表面活性剂蛋白B (SP-B1-25)可能有助于药物传递和降低皮脂水平。所有用于配制微乳的化合物在药学上是可接受的和生物相容性的。对含药体系的透皮参数进行了表征。开发了生理耐受良好且物理稳定的多组分系统。对形成稳定体系所需的表面活性剂和助表面活性剂的浓度进行了评价。利用偏振光显微镜、光子相关光谱(PCS)、电导率和流变学对微乳进行了表征。考察了异维甲酸对制备物性参数的影响。
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引用次数: 6
Title pages 标题页
Pub Date : 1900-01-01 DOI: 10.14220/9783737006552.front
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引用次数: 0
期刊
2009 International Conference on Biomedical and Pharmaceutical Engineering
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