Pub Date : 2019-02-01DOI: 10.16875/STEM.2019.20.1.213
Seung hee Jin
The present study aims to develop a flipped classroom (or flipped learning) plan using mobile collaborative learning in order to promote students’...
本研究旨在开发一套利用移动协同学习的翻转课堂(或翻转学习)计划，以促进学生的…
{"title":"초등영어 교육에서 문화간 의사소통 능력 향상을 위한 모바일 협력학습 기반 플립러닝 수업 방안","authors":"Seung hee Jin","doi":"10.16875/STEM.2019.20.1.213","DOIUrl":"https://doi.org/10.16875/STEM.2019.20.1.213","url":null,"abstract":"The present study aims to develop a flipped classroom (or flipped learning) plan using mobile collaborative learning in order to promote students’...","PeriodicalId":38955,"journal":{"name":"Open Stem Cell Journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89359346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-02-01DOI: 10.16875/stem.2019.20.1.1
노윤아
{"title":"혼돈/복잡성 이론(Chaos/Complexity Theory) 관점에 따른 영화 영어 학습에서의 ‘Interaction’ 연구","authors":"노윤아","doi":"10.16875/stem.2019.20.1.1","DOIUrl":"https://doi.org/10.16875/stem.2019.20.1.1","url":null,"abstract":"","PeriodicalId":38955,"journal":{"name":"Open Stem Cell Journal","volume":"220 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76500147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-02-01DOI: 10.16875/STEM.2019.20.1.69
주미란
This study exemplifies an English poetry class using movies where well-known poems are recited. It also investigates how the learners perceive the...
本研究以英语诗歌课为例，利用电影朗诵著名诗歌。它还调查了学习者如何感知……
{"title":"영화를 활용한 영시 수업 연구","authors":"주미란","doi":"10.16875/STEM.2019.20.1.69","DOIUrl":"https://doi.org/10.16875/STEM.2019.20.1.69","url":null,"abstract":"This study exemplifies an English poetry class using movies where well-known poems are recited. It also investigates how the learners perceive the...","PeriodicalId":38955,"journal":{"name":"Open Stem Cell Journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82206753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-02-01DOI: 10.16875/STEM.2019.20.1.119
J. Sung
The aim of this paper is to explore the benefits of and challenges to teacher collaboration in designing and implementing multimedia-assisted English...
本文的目的是探讨教师合作在设计和实施多媒体辅助英语教学中的好处和挑战。
{"title":"영어로 진행하는 멀티미디어 영문법 수업 설계와 실행을 위한 교사 협력 연구","authors":"J. Sung","doi":"10.16875/STEM.2019.20.1.119","DOIUrl":"https://doi.org/10.16875/STEM.2019.20.1.119","url":null,"abstract":"The aim of this paper is to explore the benefits of and challenges to teacher collaboration in designing and implementing multimedia-assisted English...","PeriodicalId":38955,"journal":{"name":"Open Stem Cell Journal","volume":"76 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74459892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-30DOI: 10.2174/1876893801805010047
M. Morsy, M. Hossain, A. Bagul
Normothermic Machine Perfusion (NMP) has been established in the field of solid organ transplantation for both liver and kidney allografts. The ability to perfuse organs at body temperature enables viability assessment as well as optimisation prior to implantation. A recent in vitro report of the use of Mesenchymal Stem Cells (MSCs) in the use of a normothermic lung perfusion circuit has raised the possibility of their use in solid organ transplantation. The aim of this short review is to outline the potential uses of bone marrow derived MSCs for their use in renal allograft ex vivo NMP. An overview is provided of current literature of NMP as well as theorised uses for MSCs.
{"title":"Exploring the Role of Mesenchymal Stem Cells During Normothermic Organ Perfusion: A New Paradigm to Enhance Outcome Following Allograft Transplantation","authors":"M. Morsy, M. Hossain, A. Bagul","doi":"10.2174/1876893801805010047","DOIUrl":"https://doi.org/10.2174/1876893801805010047","url":null,"abstract":"\u0000 \u0000 Normothermic Machine Perfusion (NMP) has been established in the field of solid organ transplantation for both liver and kidney allografts. The ability to perfuse organs at body temperature enables viability assessment as well as optimisation prior to implantation.\u0000 \u0000 \u0000 \u0000 A recent in vitro report of the use of Mesenchymal Stem Cells (MSCs) in the use of a normothermic lung perfusion circuit has raised the possibility of their use in solid organ transplantation. The aim of this short review is to outline the potential uses of bone marrow derived MSCs for their use in renal allograft ex vivo NMP. An overview is provided of current literature of NMP as well as theorised uses for MSCs.\u0000","PeriodicalId":38955,"journal":{"name":"Open Stem Cell Journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68150563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-23DOI: 10.2174/1876893801805010031
B. Chatterji, Godiwala Mehvash, Sunder Roma
According to WHO, 285 million people are visually impaired out of which, 39 million are classified as blind and the remaining 246 million people have low vision which comprises of moderate vision impairment and severe vision impairment. Therapies to treat major disorders leading to visual impairment like Age-related Macular Degeneration (AMD), Stargardt’s Disease (STGD), Retinitis Pigmentosa (RP) and corneal scarring are required.In the last decade, many advances have been made to treat these disorders using stem cell therapy. For corneal damage by accidental burns, scarring or limbal stem cell deficiencies which can lead to partial or total blindness, are treated with a risky intervention like keratoplasty. To overcome issues like graft rejection caused by keratoplasty as well as have a better outcome, limbal stem cell therapy has been introduced. Similarly, Retinal Pigment Epithelium (RPE) is a supporting tissue essential in nutrient transport, production of growth factors, phagocytosis of the photoreceptors and retinol cycling.Degeneration of this monolayer causes many diseases that have no prevailing treatment; however, research is being carried out to replace this simple epithelial monolayer primarily with an autologous source of cells and currently using stem cells. This review discusses the advances made in the field of ocular stem cell therapy with regards to development, cultivation and novel methods used to deliver these cells to replace the corneal and retinal epithelium as a new standard for treatment.
{"title":"Ocular Stem Cells to Treat Retinal and Corneal Disorders","authors":"B. Chatterji, Godiwala Mehvash, Sunder Roma","doi":"10.2174/1876893801805010031","DOIUrl":"https://doi.org/10.2174/1876893801805010031","url":null,"abstract":"According to WHO, 285 million people are visually impaired out of which, 39 million are classified as blind and the remaining 246 million people have low vision which comprises of moderate vision impairment and severe vision impairment. Therapies to treat major disorders leading to visual impairment like Age-related Macular Degeneration (AMD), Stargardt’s Disease (STGD), Retinitis Pigmentosa (RP) and corneal scarring are required.In the last decade, many advances have been made to treat these disorders using stem cell therapy. For corneal damage by accidental burns, scarring or limbal stem cell deficiencies which can lead to partial or total blindness, are treated with a risky intervention like keratoplasty. To overcome issues like graft rejection caused by keratoplasty as well as have a better outcome, limbal stem cell therapy has been introduced. Similarly, Retinal Pigment Epithelium (RPE) is a supporting tissue essential in nutrient transport, production of growth factors, phagocytosis of the photoreceptors and retinol cycling.Degeneration of this monolayer causes many diseases that have no prevailing treatment; however, research is being carried out to replace this simple epithelial monolayer primarily with an autologous source of cells and currently using stem cells. This review discusses the advances made in the field of ocular stem cell therapy with regards to development, cultivation and novel methods used to deliver these cells to replace the corneal and retinal epithelium as a new standard for treatment.","PeriodicalId":38955,"journal":{"name":"Open Stem Cell Journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43701019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-23DOI: 10.2174/1876893801805010014
N. Bigdeli, G. D. Peppo, C. Karlsson, Maria Lennerås, R. Strehl, J. Hyllner, A. Lindahl
Despite recent advances in culture techniques for undifferentiated human Embryonic Stem Cells (hESCs), further improvements are required to facilitate research and translation of these cells in clinical settings. We have previously derived hESC lines that can be cultured in their undifferentiated state on regular plastic culture dishes, without the need for feeder cells or other coating supports, denoted Matrix-Free Growth hESCs (MFG-hESCs). In this study, we further characterize and compare MFG-hESCs to hESCs in order to understand the molecular differences responsible for the unique ability of MFG-hESCs. Microarray analysis demonstrated that MFG-hESCs highly resemble feeder-cultured hESCs in global gene expression profile. Two identified groups of genes with differential expression were those encoding for ribosomal proteins and attachment proteins, such as the RGD (Arg-Gly-Asp)-associated proteins. Real-time PCR and flow cytometry corroborated the microarray results. Culture of MFG-hESCs in the presence of RGD peptides resulted in decreased attachment ability compared to cells cultured in the presence of RGES (Arg-Gly-Asp-Ser) peptides. This study demonstrates that MFG-hESC lines overexpress cell attachment proteins but retain the typical characteristics of undifferentiated feeder-cultured hESCs. The ability to culture high-quality pluripotent stem cells in feeder- and matrix-free conditions creates a new opportunities for their large-scale manufacturing for experimental research and translational applications.
{"title":"Upregulation of Adhesion Molecules Sustains Matrix-Free Growth of Human Embryonic Stem Cells","authors":"N. Bigdeli, G. D. Peppo, C. Karlsson, Maria Lennerås, R. Strehl, J. Hyllner, A. Lindahl","doi":"10.2174/1876893801805010014","DOIUrl":"https://doi.org/10.2174/1876893801805010014","url":null,"abstract":"\u0000 \u0000 Despite recent advances in culture techniques for undifferentiated human Embryonic Stem Cells (hESCs), further improvements are required to facilitate research and translation of these cells in clinical settings. We have previously derived hESC lines that can be cultured in their undifferentiated state on regular plastic culture dishes, without the need for feeder cells or other coating supports, denoted Matrix-Free Growth hESCs (MFG-hESCs).\u0000 \u0000 \u0000 \u0000 In this study, we further characterize and compare MFG-hESCs to hESCs in order to understand the molecular differences responsible for the unique ability of MFG-hESCs.\u0000 \u0000 \u0000 \u0000 Microarray analysis demonstrated that MFG-hESCs highly resemble feeder-cultured hESCs in global gene expression profile. Two identified groups of genes with differential expression were those encoding for ribosomal proteins and attachment proteins, such as the RGD (Arg-Gly-Asp)-associated proteins. Real-time PCR and flow cytometry corroborated the microarray results. Culture of MFG-hESCs in the presence of RGD peptides resulted in decreased attachment ability compared to cells cultured in the presence of RGES (Arg-Gly-Asp-Ser) peptides.\u0000 \u0000 \u0000 \u0000 This study demonstrates that MFG-hESC lines overexpress cell attachment proteins but retain the typical characteristics of undifferentiated feeder-cultured hESCs. The ability to culture high-quality pluripotent stem cells in feeder- and matrix-free conditions creates a new opportunities for their large-scale manufacturing for experimental research and translational applications.\u0000","PeriodicalId":38955,"journal":{"name":"Open Stem Cell Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49121716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-01DOI: 10.16875/stem.2018.19.4.91
임주영
{"title":"Utilizing Flipped Learning in the English Language Classroom: A Study on a Movie, Love Actually-Based Curriculum","authors":"임주영","doi":"10.16875/stem.2018.19.4.91","DOIUrl":"https://doi.org/10.16875/stem.2018.19.4.91","url":null,"abstract":"","PeriodicalId":38955,"journal":{"name":"Open Stem Cell Journal","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74601637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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